phenobarbital and midazolam

phenobarbital has been researched along with midazolam in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.53)	18.7374
1990's	13 (16.46)	18.2507
2000's	27 (34.18)	29.6817
2010's	24 (30.38)	24.3611
2020's	13 (16.46)	2.80

Authors

Authors	Studies
Beck, WT; Schuetz, EG; Schuetz, JD	1
Topliss, JG; Yoshida, F	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Breimer, DD; de Boer, AG; van Hoogdalem, E	1
Gil-Salú, JL; Gómez-Cárdenas, E; Gonzàlez-Darder, JM; Guerrero, M; Segura-Pastor, D	1
Andrews, JS; Bortolotto, ZA; Bressler, K; Calderazzo-Filho, LS; Cavalheiro, EA; Löschmann, PA; Turski, L	1
Franceschetti, S; Hamon, B; Heinemann, U; Konnerth, A; Yaari, Y	1
Kolis, SJ; Sasso, GJ; Schwartz, MA; Warinsky, D; Williams, TH; Woo, GK	1
García-Teno, M; González-Darder, JM	1
Deshpande, JK; Gregory, DF; Tobias, JD	1
Steinhoff, BJ; Stodieck, SR	1
Cascino, GD	1
Burke, AL	1
Francischi, JN; Pesquero, SM; Salgado, JV; Santana, MA; Tatsuo, MA; Yokoro, CM	1
Aminoff, MJ	1
Dreier, JP; Heinemann, U; Zhang, CL	1
Bleck, TP	2
Fiallos, MR; Hanhan, UA; Orlowski, JP	1
Bijsterbosch, MK; Commandeur, JN; Hoen, PA; van Berkel, TJ; Vermeulen, NP	1
Fukumizu, M; Hanaoka, S; Mimaki, M; Miyamoto, T; Sasaki, M; Sudoh, A; Sugai, K	1
Claassen, J; Hirsch, LJ	1
Rekling, JC	1
Sykes, N; Thorns, A	1
Al Riyami, K; Chacko, A; Javed, H; Koul, R	1
Fujikawa, Y; Fukumizu, M; Hanaoka, S; Kaga, M; Sasaki, M; Sugai, K	1
Binnie, CD; Boylan, GB; Chorley, G; Farrer, K; Fox, GF; Morton, M; Pressler, RM; Rennie, JM	1
Castro Conde, JR; Doménech Martínez, E; González Campo, C; Hernández Borges, AA; Perera Soler, R	1
Walker, M	1
Al-Roomi, K; Krishnan, PR; Prasad, K; Sequeira, R	2
Malmgren, K	1
Iwaki, H; Iwakiri, K; Kaneshiro, Y; Masada, T; Oda, Y; Ohashi, H; Takaoka, K	1
Liyanage, UA; Wanigasinghe, J	1
Chen, J; Cohen, N; Nadkarni, A; Orsini, J	1
deCaen, AR; Duff, J; Joffe, AR; Kolski, H	1
Jackson, AC	1
Gulati, S; Lodha, R; Raj, D	1
Hayashi, M; Shou, M; Skiles, GL; Xu, Y; Zhou, Y	1
Aribogan, A; Arslan, G; Eker, HE; Yalcin Cok, O	1
Bos, AF; Brouwer, OF; Roze, E; Ter Horst, HJ; van der Heide, MJ; van der Veere, CN	1
Arai, Y; Higuchi, H; Maeda, S; Miyawaki, T; Shimada, M; Tomoyasu, Y	1
de Vries, LS; Hellström-Westas, L; van Rooij, LG	1
Yamanouchi, H	1
Hirose, S; Ihara, Y; Ishii, A; Izumi, T; Maeda, T; Sekiguchi, K; Shimizu, M	1
Al-Roomi, K; Krishnan, PR; Prasad, M; Sequeira, R	1
Djuric, M; Jankovic, B; Kravljanac, R; Pekmezovic, T	1
Hammann, F; Haschke, M; Krähenbühl, S; Kummer, O	1
Bidegain, M; Cotten, CM; Edwards, LE; Hornik, CD; Hutchison, LB; Smith, PB	1
Niquet, J; Suchomelova, L; Torolira, D; Wasterlain, CG	1
Baba, M; Beringer, A; Harris, N; Mellor, C; Rogers, R; Sharples, P; Taylor, K	1
El-Dib, M; Soul, JS	1
Chakrabarty, B; Gulati, S; Jauhari, P; Lodha, R; Sankar, J; Sondhi, V	1
Chen, J; Hu, Y; Jiang, L; Lan, X; Xie, L	1
Allegaert, K; Smits, A; van den Anker, JN	1
Cools, F; de Haan, TR; Dijk, PH; Dijkman, KP; Egberts, TCG; Favié, LMA; Groenendaal, F; Huitema, ADR; Nuytemans, DHGM; Rademaker, CMA; Rijken, M; Simons, SHP; van Bel, F; van den Broek, MPH; van der Lee, JH; van Heijst, A; van Straaten, HLM; Zecic, A; Zonnenberg, IA	1
Bakker, M; Kleinig, P; Patel, C; Tait, P	1
Ala-Kurikka, T; Gailus, B; Hampel, P; Johne, M; Kaila, K; Löscher, W; Römermann, K; Theilmann, W	1
Bacon, M; Chatterjee, F; Lampariello, S; Venkateswaran, R; Wood, H; Yoong, M; Zombori, L	1
Chuck, CC; Claassen, J; Han, EJ; Madsen, TE; Martin, TJ; Reznik, ME	1
Ben-Ari, Y; Delpire, E	1
Lumley, LA; Marrero-Rosado, B; Niquet, J; Rossetti, F; Schultz, CR; Stone, MF; Wasterlain, CG	1
Babl, FE; Borland, ML; Dalziel, SR; Emeto, TI; Furyk, JS; George, S; Hearps, SJ; O'Brien, S; Phillips, N; Riney, K; Watt, K; Wilson, C	1
Brunner, KR; Capuano, S; Crosno, K; Fuhler, NA; Ikonomidou, C; Larson, S; Mejia, AF; Noguchi, KK; Simmons, HA; Wang, SH	1
Criscione, R; Falsaperla, R; Marino, S; Pisani, F; Praticò, A; Ruggieri, M; Sortino, V	1
Johne, M; Löscher, W; Welzel, B	1
Feeney, ME; Steiling, K	1
Banzi, R; Bruschettini, M; Calevo, MG; Ley, D; Paraskevas, T; Romantsik, O; Stróżyk, A	1
Czabanka, M; Kieslich, M; Merker, M; Purwien, L; Ronellenfitsch, MW; Rosenow, F; Schubert-Bast, S; Strzelczyk, A; Willems, LM	1

Reviews

21 review(s) available for phenobarbital and midazolam

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs. Clinical pharmacokinetics, 1991, Volume: 21, Issue:1 Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid	1991
Palliative care: an update on "terminal restlessness". The Medical journal of Australia, 1997, Jan-06, Volume: 166, Issue:1 Topics: Anti-Anxiety Agents; Anticonvulsants; Antipsychotic Agents; Clonazepam; Delirium; Diazepam; Humans; Midazolam; Palliative Care; Phenobarbital; Psychomotor Agitation; Terminal Care	1997
Management of status epilepticus. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1998, Volume: 25, Issue:1 Topics: Anticonvulsants; Electroencephalography; Humans; Midazolam; Phenobarbital; Practice Guidelines as Topic; Status Epilepticus	1998
Management approaches to prolonged seizures and status epilepticus. Epilepsia, 1999, Volume: 40 Suppl 1 Topics: Anticonvulsants; Benzodiazepines; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Treatment Outcome	1999
Status epilepticus. Pediatric clinics of North America, 2001, Volume: 48, Issue:3 Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Midazolam; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid	2001
The current state of treatment of status epilepticus. Current neurology and neuroscience reports, 2002, Volume: 2, Issue:4 Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Electroencephalography; Female; GABA Modulators; Humans; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus; Treatment Outcome; Valproic Acid	2002
Status epilepticus: an evidence based guide. BMJ (Clinical research ed.), 2005, Sep-24, Volume: 331, Issue:7518 Topics: Anticonvulsants; Chronic Disease; Critical Care; Drug Administration Routes; Emergency Treatment; Evidence-Based Medicine; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Prognosis; Randomized Controlled Trials as Topic; Referral and Consultation; Status Epilepticus	2005
Anticonvulsant therapy for status epilepticus. The Cochrane database of systematic reviews, 2005, Oct-19, Issue:4 Topics: Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus	2005
Anticonvulsant therapy for status epilepticus. British journal of clinical pharmacology, 2007, Volume: 63, Issue:6 Topics: Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus	2007
Intensive care unit management of patients with status epilepticus. Epilepsia, 2007, Volume: 48 Suppl 8 Topics: Anesthesia, General; Anticonvulsants; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Humans; Intensive Care Units; Levetiracetam; Midazolam; Patient Care Management; Phenobarbital; Piracetam; Propofol; Status Epilepticus	2007
Propofol infusion syndrome: case report and literature review. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2009, May-15, Volume: 66, Issue:10 Topics: Adult; Anesthetics, Intravenous; Drug Administration Schedule; Exanthema; Female; Hepatomegaly; Humans; Hypnotics and Sedatives; Midazolam; Phenobarbital; Propofol; Risk Factors; Syndrome; Tachycardia, Sinus	2009
Treatment of neonatal seizures. Seminars in fetal & neonatal medicine, 2013, Volume: 18, Issue:4 Topics: Animals; Anticonvulsants; Brain; Child Development; Drug Resistance; Epilepsy; Humans; Infant, Newborn; Infant, Premature; Lidocaine; Midazolam; Neurogenesis; Neurons; Neuroprotective Agents; Phenobarbital; Premature Birth; Seizures; Severity of Illness Index	2013
[Treatment of status epilepticus]. Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:5 Topics: Anesthesia, General; Diazepam; Drug Administration Routes; Evidence-Based Medicine; Humans; Hypothermia, Induced; Intensive Care Units; Midazolam; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Propofol; Status Epilepticus; Thiopental; Time Factors	2014
Anticonvulsant therapy for status epilepticus. The Cochrane database of systematic reviews, 2014, Sep-10, Issue:9 Topics: Anticonvulsants; Diazepam; Humans; Injections, Intravenous; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus	2014
Seizure management in children requiring palliative care: a review of current practice. BMJ supportive & palliative care, 2020, Volume: 10, Issue:3 Topics: Anticonvulsants; Child; Child, Preschool; England; Female; Humans; Infant; Infusions, Intravenous; Male; Midazolam; Palliative Care; Phenobarbital; Retrospective Studies; Seizures; Terminal Care; Treatment Outcome	2020
The use of phenobarbital and other anti-seizure drugs in newborns. Seminars in fetal & neonatal medicine, 2017, Volume: 22, Issue:5 Topics: Anticonvulsants; Fructose; Humans; Hypothermia, Induced; Infant, Newborn; Lidocaine; Midazolam; Phenobarbital; Seizures; Topiramate; Treatment Outcome	2017
High dose phenobarbitone coma in pediatric refractory status epilepticus; a retrospective case record analysis, a proposed protocol and review of literature. Brain & development, 2018, Volume: 40, Issue:4 Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clinical Protocols; Coma; Drug Resistance; Female; Humans; Infant; Male; Midazolam; Phenobarbital; Retrospective Studies; Status Epilepticus	2018
Palliative sedation: A safety net for the relief of refractory and intolerable symptoms at the end of life. Australian journal of general practice, 2019, Volume: 48, Issue:12 Topics: Aged; Analgesics; Conscious Sedation; Dehydration; Dyspnea; Humans; Hydromorphone; Hypnotics and Sedatives; Male; Methotrimeprazine; Midazolam; Multiple Myeloma; Multiple Organ Failure; Pain; Palliative Care; Phenobarbital; Propofol; Psychomotor Agitation; Sepsis; Terminal Care	2019
Efficacy of the anti-seizure medications in acute symptomatic neonatal seizures caused by stroke. A systematic review. Acta bio-medica : Atenei Parmensis, 2022, 12-16, Volume: 93, Issue:6 Topics: Anticonvulsants; Bumetanide; Epilepsy; Humans; Infant, Newborn; Infant, Newborn, Diseases; Levetiracetam; Lidocaine; Midazolam; Phenobarbital; Stroke	2022
Pharmacological pain and sedation interventions for the prevention of intraventricular hemorrhage in preterm infants on assisted ventilation - an overview of systematic reviews. The Cochrane database of systematic reviews, 2023, 08-11, Volume: 8 Topics: Acetaminophen; Analgesics, Opioid; Cerebral Hemorrhage; Female; Heroin; Humans; Ibuprofen; Infant, Newborn; Infant, Premature; Midazolam; Pain; Perinatal Death; Phenobarbital; Respiration, Artificial; Systematic Reviews as Topic	2023

Trials

4 trial(s) available for phenobarbital and midazolam

Article	Year
Eight-year study of childhood status epilepticus: midazolam infusion in management and outcome. Journal of child neurology, 2002, Volume: 17, Issue:12 Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Female; GABA Modulators; Humans; Infant; Infusions, Intravenous; Injections, Intravenous; Male; Midazolam; Phenobarbital; Phenytoin; Status Epilepticus; Treatment Outcome	2002
Second-line anticonvulsant treatment of neonatal seizures: a video-EEG monitoring study. Neurology, 2004, Feb-10, Volume: 62, Issue:3 Topics: Anticonvulsants; Clonazepam; Drug Resistance; Electroencephalography; Epilepsy; Female; Humans; Infant, Newborn; Lidocaine; Male; Midazolam; Phenobarbital; Psychomotor Disorders; Treatment Failure; Video Recording	2004
Midazolam in neonatal seizures with no response to phenobarbital. Neurology, 2005, Mar-08, Volume: 64, Issue:5 Topics: Age Factors; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Epilepsy, Benign Neonatal; GABA Modulators; Humans; Infant, Newborn; Midazolam; Phenobarbital; Retrospective Studies; Seizures; Treatment Outcome	2005
Children on phenobarbital monotherapy requires more sedatives during MRI. Paediatric anaesthesia, 2011, Volume: 21, Issue:10 Topics: Anesthetics, Dissociative; Anticonvulsants; Child; Child, Preschool; Conscious Sedation; Double-Blind Method; Epilepsy; Female; Humans; Hypnotics and Sedatives; Infant; Ketamine; Magnetic Resonance Imaging; Male; Midazolam; Phenobarbital; Prospective Studies; Recovery Room	2011

Other Studies

54 other study(ies) available for phenobarbital and midazolam

Article	Year
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. Molecular pharmacology, 1996, Volume: 49, Issue:2 Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, Northern; Cell Line; Clotrimazole; Colonic Neoplasms; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dexamethasone; DNA Primers; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Midazolam; Mixed Function Oxygenases; Molecular Sequence Data; Multigene Family; Phenobarbital; Phenytoin; Polymerase Chain Reaction; Rifampin; Tumor Cells, Cultured; Verapamil	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development. Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Intrathecal antiepileptic drugs in experimental epilepsy. Stereotactic and functional neurosurgery, 1991, Volume: 57, Issue:3 Topics: Animals; Anticonvulsants; Catheters, Indwelling; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Hemodynamics; Infusions, Parenteral; Male; Midazolam; Phenobarbital; Rats; Rats, Inbred Strains; Valproic Acid	1991
Substantia nigra regulates action of antiepileptic drugs. Brain research, 1990, Jun-18, Volume: 520, Issue:1-2 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Ethosuximide; Male; Microinjections; Midazolam; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra; Trimethadione	1990
Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slices. Brain research, 1985, Jan-28, Volume: 325, Issue:1-2 Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Cell Membrane Permeability; Epilepsy; Hippocampus; In Vitro Techniques; Ion Channels; Midazolam; Phenobarbital; Phenytoin; Rats; Valproic Acid	1985
Biotransformation of [14C]midazolam in the rat in vitro and in vivo. Xenobiotica; the fate of foreign compounds in biological systems, 1981, Volume: 11, Issue:6 Topics: Animals; Benzodiazepines; Bile; Biotransformation; Liver; Male; Midazolam; Models, Biological; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Tissue Distribution	1981
Anticonvulsant effect of intraventricular antiepileptic drugs. Experimental study. Neurological research, 1995, Volume: 17, Issue:3 Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Epilepsy; Injections, Intraventricular; Male; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid	1995
Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit. Intensive care medicine, 1994, Volume: 20, Issue:7 Topics: Child; Female; Fentanyl; Humans; Iatrogenic Disease; Infant; Lorazepam; Male; Methadone; Midazolam; Phenobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders	1994
Temporary abolition of seizure activity by flumazenil in a case of valproate-induced non-convulsive status epilepticus. Seizure, 1993, Volume: 2, Issue:3 Topics: Adult; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Evoked Potentials; Female; Flumazenil; Humans; Midazolam; Phenobarbital; Seizures; Status Epilepticus; Valproic Acid	1993
Generalized convulsive status epilepticus. Mayo Clinic proceedings, 1996, Volume: 71, Issue:8 Topics: Adolescent; Adult; Aged; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy, Generalized; Humans; Isoflurane; Midazolam; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus	1996
Hyperalgesic effect induced by barbiturates, midazolam and ethanol: pharmacological evidence for GABA-A receptor involvement. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 1997, Volume: 30, Issue:2 Topics: Animals; Barbiturates; Central Nervous System Depressants; Ethanol; GABA Antagonists; GABA Modulators; Hyperalgesia; Male; Midazolam; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Thiopental	1997
Phenytoin, phenobarbital, and midazolam fail to stop status epilepticus-like activity induced by low magnesium in rat entorhinal slices, but can prevent its development. Acta neurologica Scandinavica, 1998, Volume: 98, Issue:3 Topics: Animals; Anticonvulsants; Carbamazepine; Culture Techniques; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Entorhinal Cortex; Magnesium; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Status Epilepticus	1998
Midazolam is a phenobarbital-like cytochrome p450 inducer in rats. The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:3 Topics: Animals; Anti-Anxiety Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Hypnotics and Sedatives; Male; Midazolam; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Sprague-Dawley; RNA, Messenger	2001
[Non-intravenous high-dose phenobarbital therapy for status epilepticus refractory to continuous infusion of midazolam or pentobarbital: report of three cases]. No to hattatsu = Brain and development, 2002, Volume: 34, Issue:1 Topics: Adult; Anticonvulsants; Child, Preschool; Electroencephalography; Female; Humans; Infant; Infusions, Intravenous; Male; Midazolam; Pentobarbital; Phenobarbital; Status Epilepticus	2002
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation. Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3 Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid	2003
Sedative use in the last week of life and the implications for end-of-life decision making. Archives of internal medicine, 2003, Feb-10, Volume: 163, Issue:3 Topics: Adult; Aged; Anticonvulsants; Decision Making; Delirium; Double Effect Principle; Ethics, Clinical; Ethics, Medical; Female; Humans; Hypnotics and Sedatives; Male; Methotrimeprazine; Midazolam; Middle Aged; Palliative Care; Phenobarbital; Propofol; Status Epilepticus; Survival Analysis; Terminal Care; Time Factors; United States	2003
[Three cases with severe motor and intellectual disabilities presenting the severest condition caused by prolonged non-convulsive status epilepticus]. No to hattatsu = Brain and development, 2003, Volume: 35, Issue:1 Topics: Child, Preschool; Disabled Children; Disease Progression; Electroencephalography; Female; Humans; Infusions, Intravenous; Male; Midazolam; Phenobarbital; Psychomotor Disorders; Severity of Illness Index; Status Epilepticus; Thiopental; Vitamin B 6	2003
[Management of status epilepticus]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2005, Volume: 105, Issue:10 Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child; Diazepam; Drug Therapy, Combination; Electroencephalography; Humans; Infant; Infant, Newborn; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Prognosis; Propofol; Randomized Controlled Trials as Topic; Status Epilepticus	2005
Increased hepatic cytochrome P4503A activity decreases the risk of developing steroid-induced osteonecrosis in a rabbit model. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2008, Volume: 26, Issue:1 Topics: Anesthetics, Intravenous; Animals; Antifungal Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Enzyme Induction; Excitatory Amino Acid Antagonists; Female; Femur Head Necrosis; Glucocorticoids; Incidence; Itraconazole; Liver; Methylprednisolone; Midazolam; Phenobarbital; Prevalence; Rabbits; Risk Factors	2008
Audit of treatment of convulsive status epilepticus. The Ceylon medical journal, 2008, Volume: 53, Issue:3 Topics: Anticonvulsants; Child; Diazepam; Humans; Midazolam; Paraldehyde; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Status Epilepticus	2008
A 10-month-old infant with reversible findings of brain death. Pediatric neurology, 2009, Volume: 41, Issue:5 Topics: Brain; Brain Death; Drowning; Electroencephalography; Excitatory Amino Acid Antagonists; GABA Modulators; Humans; Infant; Male; Midazolam; Near Drowning; Phenobarbital; Time Factors; Treatment Outcome	2009
Therapy of rabies encephalitis. Biomedica : revista del Instituto Nacional de Salud, 2009, Volume: 29, Issue:2 Topics: Adolescent; Amantadine; Animals; Antibodies, Neutralizing; Antibodies, Viral; Antiviral Agents; Chiroptera; Clinical Protocols; Combined Modality Therapy; Deep Sedation; Electroencephalography; Encephalitis, Viral; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Midazolam; Phenobarbital; Rabies; Rabies virus; Ribavirin	2009
Status epilepticus. Indian journal of pediatrics, 2011, Volume: 78, Issue:2 Topics: Anticonvulsants; Benzodiazepines; Child; Clinical Protocols; Fructose; GABA Modulators; Humans; Ketamine; Levetiracetam; Midazolam; Pentobarbital; Phenobarbital; Phenytoin; Piracetam; Propofol; Status Epilepticus; Thiopental; Topiramate; Valproic Acid	2011
Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Midazolam; Nifedipine; Phenobarbital; Rifampin; Simvastatin; Substrate Specificity	2011
Long-term neurological outcome of term-born children treated with two or more anti-epileptic drugs during the neonatal period. Early human development, 2012, Volume: 88, Issue:1 Topics: Anticonvulsants; Apgar Score; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Lidocaine; Logistic Models; Male; Midazolam; Phenobarbital; Prognosis; Risk Factors; Treatment Outcome	2012
Effects of midazolam and phenobarbital on brain oxidative reactions induced by pentylenetetrazole in a convulsion model. Immunopharmacology and immunotoxicology, 2012, Volume: 34, Issue:2 Topics: Animals; Brain; Cerebral Cortex; Disease Models, Animal; Gene Expression; Heme Oxygenase-1; Hippocampus; Hypothalamus; Male; Malondialdehyde; Mice; Midazolam; Oxidation-Reduction; Pentylenetetrazole; Phenobarbital; Seizures; Treatment Outcome	2012
Exacerbation of benign familial neonatal epilepsy induced by massive doses of phenobarbital and midazolam. Pediatric neurology, 2014, Volume: 51, Issue:2 Topics: Electroencephalography; Epilepsy, Benign Neonatal; Female; GABA Modulators; Humans; Midazolam; Phenobarbital; Seizures	2014
Etiology, clinical course and response to the treatment of status epilepticus in children: A 16-year single-center experience based on 602 episodes of status epilepticus. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2015, Volume: 19, Issue:5 Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Infusions, Intravenous; Male; Midazolam; Phenobarbital; Retrospective Studies; Seizures; Status Epilepticus	2015
Reduction of hyperbilirubinemia with hypericum extract (St. John's Wort) in a patient with Crigler-Najjar syndrome type II. British journal of clinical pharmacology, 2016, Volume: 81, Issue:5 Topics: Adult; Area Under Curve; Bilirubin; Crigler-Najjar Syndrome; Cytochrome P-450 CYP3A; Enzyme Induction; Female; GABA Modulators; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Hypericum; Midazolam; Phenobarbital; Plant Extracts; Pregnane X Receptor; Receptors, Steroid; Young Adult	2016
A case of infant delirium in the neonatal intensive care unit. Journal of neonatal-perinatal medicine, 2017, Volume: 10, Issue:1 Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Cardiac Catheterization; Cyclohexanecarboxylic Acids; Delirium; Deprescriptions; Dexmedetomidine; Diazepam; Female; Fentanyl; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Premature; Intensive Care Units, Neonatal; Methadone; Midazolam; Phenobarbital; Postoperative Complications; Pregnancy; Respiration, Artificial; Respiratory Distress Syndrome, Newborn; Risperidone	2017
Phenobarbital and midazolam increase neonatal seizure-associated neuronal injury. Annals of neurology, 2017, Volume: 82, Issue:1 Topics: Animals; Apoptosis; Brain; Cell Count; Female; Male; Midazolam; Neurons; Phenobarbital; Rats; Status Epilepticus	2017
Nonconvulsive status epilepticus after cessation of convulsive status epilepticus in pediatric intensive care unit patients. Epilepsy & behavior : E&B, 2018, Volume: 82 Topics: Administration, Intravenous; Adolescent; Cerebral Cortex; Child; Child, Preschool; Electroencephalography; Female; Follow-Up Studies; Humans; Infant; Intensive Care Units, Pediatric; Male; Midazolam; Phenobarbital; Propofol; Retrospective Studies; Status Epilepticus	2018
Phenobarbital Increases Midazolam Clearance in Neonates Treated with Hypothermia: Do We Really Need to Know? Neonatology, 2019, Volume: 116, Issue:2 Topics: Anticonvulsants; Asphyxia Neonatorum; Drug Therapy, Combination; Humans; Hypothermia, Induced; Infant, Newborn; Metabolic Clearance Rate; Midazolam; Phenobarbital	2019
Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia. Neonatology, 2019, Volume: 116, Issue:2 Topics: Anticonvulsants; Asphyxia Neonatorum; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypothermia, Induced; Hypoxia-Ischemia, Brain; Infant, Newborn; Male; Metabolic Clearance Rate; Midazolam; Phenobarbital; Practice Guidelines as Topic; Prospective Studies	2019
Phenobarbital and midazolam suppress neonatal seizures in a noninvasive rat model of birth asphyxia, whereas bumetanide is ineffective. Epilepsia, 2021, Volume: 62, Issue:4 Topics: Animals; Animals, Newborn; Anticonvulsants; Asphyxia Neonatorum; Bumetanide; Disease Models, Animal; Female; Hypnotics and Sedatives; Male; Midazolam; Phenobarbital; Rats; Rats, Wistar; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Treatment Outcome	2021
Severe cortical damage associated with COVID-19 case report. Seizure, 2021, Volume: 84 Topics: Acute Kidney Injury; Adolescent; Airway Extubation; Anticonvulsants; Blood Coagulation Disorders; Bone Marrow Failure Disorders; Brain Diseases; Brain Edema; C-Reactive Protein; COVID-19; De Lange Syndrome; Disease Progression; Electroencephalography; Epilepsy; Female; Ferritins; Humans; Influenza B virus; Influenza, Human; Levetiracetam; Magnetic Resonance Imaging; Midazolam; Necrosis; Phenobarbital; Pseudomonas Infections; Respiration, Artificial; Rhabdomyolysis; SARS-CoV-2; Seizures; Sepsis; Systemic Inflammatory Response Syndrome; Tachycardia, Ventricular	2021
Statewide Emergency Medical Services Protocols for Status Epilepticus Management. Annals of neurology, 2021, Volume: 89, Issue:3 Topics: Administration, Intranasal; Administration, Rectal; Adult; Anticonvulsants; Benzodiazepines; Child; Cross-Sectional Studies; Diazepam; Emergency Medical Services; Humans; Injections, Intramuscular; Injections, Intravenous; Levetiracetam; Lorazepam; Midazolam; Phenobarbital; Practice Guidelines as Topic; Status Epilepticus; United States	2021
Phenobarbital, midazolam, bumetanide, and neonatal seizures: The devil is in the details. Epilepsia, 2021, Volume: 62, Issue:4 Topics: Animals; Anticonvulsants; Bumetanide; Epilepsy; Humans; Midazolam; Phenobarbital; Prohibitins; Seizures; Solute Carrier Family 12, Member 2	2021
Combination of antiseizure medications phenobarbital, ketamine, and midazolam reduces soman-induced epileptogenesis and brain pathology in rats. Epilepsia open, 2021, Volume: 6, Issue:4 Topics: Animals; Anticonvulsants; Brain; Drug Therapy, Combination; Ketamine; Midazolam; Phenobarbital; Rats; Soman	2021
Status Epilepticus Australasian Registry for Children: A pilot prospective, observational, cohort study of paediatric status epilepticus. Emergency medicine Australasia : EMA, 2022, Volume: 34, Issue:5 Topics: Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Cohort Studies; Female; Humans; Levetiracetam; Male; Midazolam; Phenobarbital; Phenytoin; Pilot Projects; Prospective Studies; Registries; Seizures; Status Epilepticus	2022
Mild hypothermia fails to protect infant macaques from brain injury caused by prolonged exposure to Antiseizure drugs. Neurobiology of disease, 2022, Volume: 171 Topics: Animals; Brain; Brain Injuries; Humans; Hypothermia; Hypothermia, Induced; Infant; Infant, Newborn; Lead; Macaca mulatta; Midazolam; Phenobarbital; Sevoflurane	2022
Bumetanide potentiates the anti-seizure and disease-modifying effects of midazolam in a noninvasive rat model of term birth asphyxia. Epilepsy & behavior : E&B, 2023, Volume: 142 Topics: Animals; Anticonvulsants; Asphyxia; Asphyxia Neonatorum; Bumetanide; Epilepsy; Humans; Infant, Newborn; Midazolam; Phenobarbital; Rats; Seizures; Solute Carrier Family 12, Member 2; Term Birth	2023
Successful management of suspected propofol dependence with phenobarbital in an adult patient with COVID-19. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2023, 09-22, Volume: 80, Issue:19 Topics: Adult; COVID-19; Dexmedetomidine; Fentanyl; Humans; Hypertension; Hypnotics and Sedatives; Male; Midazolam; Middle Aged; Phenobarbital; Propofol	2023
Trends and Differences in Status Epilepticus Treatment of Children and Adults Over 10 Years: A Comparative Study of Medical Records (2012-2021) from a University Hospital in Germany. CNS drugs, 2023, Volume: 37, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Child; Female; Hospitals, University; Humans; Lacosamide; Levetiracetam; Male; Medical Records; Midazolam; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid	2023