phenobarbital and methylprednisolone

phenobarbital has been researched along with methylprednisolone in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199011 (39.29)18.7374
1990's5 (17.86)18.2507
2000's7 (25.00)29.6817
2010's5 (17.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gaito, JM; Miner, PB1
Byrd, A; Finn, A; Levin, VA; Stearns, J; Weinkam, RJ1
Katz, FH; Stjernholm, MR1
Ali, A; Qureshi, IA1
Sekihara, H1
Golladay, ES; Seibert, JJ; Slezak, JW1
Goldbach, M; Phillips, MJ; Roberts, EA; Spielberg, SP1
Hiley, CR; Nichols, AJ; Wilson, AC1
Barker, CF; Brayman, KL; Choti, MA; Naji, A; Nakamura, J; Shaw, LM1
Bartoszek, M; Brenner, AM; Szefler, SJ1
Marin, GA; Montoya, CA; Senior, JR; Sierra, JL1
Shiba, DA; Weinkam, RJ1
Andrews, F; Brenner, M; Ellis, EF; Jusko, WJ; Rose, JQ; Spector, SL; Szefler, SJ; Yurchak, AM1
Chiang, YH; Chiou, TL; Lin, SZ; Song, WS1
WOOLF, CR1
BANKER, GS; WOLFSON, BB1
Finch, CK; Jones, R; Mostella, J; Pieroni, R1
Iwaki, H; Iwakiri, K; Kaneshiro, Y; Masada, T; Oda, Y; Ohashi, H; Takaoka, K1
Adachi, A; Chihara, K; Hino, Y; Ibusuki, C; Kimura, K; Nakamura, S; Suematsu, N; Takahashi, N; Takata, M1
Behniafard, N; Nafei, Z; Shefai, F1

Reviews

1 review(s) available for phenobarbital and methylprednisolone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for phenobarbital and methylprednisolone

ArticleYear
Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:4

    Topics: Adolescent; Anticonvulsants; Asthma; Biological Availability; Carbamazepine; Child; Half-Life; Humans; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Research Design

1987
Evaluation of corticosteroid and exchange-transfusion treatment of acute yellow-phosphorus intoxication.
    The New England journal of medicine, 1971, Jan-21, Volume: 284, Issue:3

    Topics: Adolescent; Adult; Child; Exchange Transfusion, Whole Blood; Female; Glucocorticoids; Hepatic Encephalopathy; Humans; Liver; Liver Function Tests; Male; Methylprednisolone; Middle Aged; Neomycin; Phenobarbital; Phosphorus; Poisoning; Prospective Studies; Salts; Suicide

1971

Other Studies

25 other study(ies) available for phenobarbital and methylprednisolone

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Bile flow in response to pharmacologic agents. Hepatic DNA as a reference standard.
    Biochemical pharmacology, 1979, Apr-01, Volume: 28, Issue:7

    Topics: Animals; Bile; Body Weight; DNA; Ethinyl Estradiol; Liver; Male; Methylcholanthrene; Methylprednisolone; Organ Size; Phenobarbital; Rats

1979
The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 208, Issue:1

    Topics: Alkylating Agents; Animals; Biotransformation; Brain Neoplasms; Carmustine; Dexamethasone; Drug Interactions; In Vitro Techniques; Kinetics; Liver; Lomustine; Male; Methylprednisolone; Neoplasms, Experimental; Nitrosourea Compounds; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344

1979
Effects of diphenylhydantoin, phenobarbital, and diazepam on the metabolism of methylprednisolone and its sodium succinate.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:5

    Topics: Adult; Diazepam; Female; Half-Life; Humans; Liver; Male; Metabolic Clearance Rate; Methylprednisolone; Phenobarbital; Phenytoin; Sodium; Succinates

1975
Benzoyl-CoA ligase activity in the liver and kidney cortex of weanling guinea pigs treated with various inducers: relationship with hippurate synthesis and carnitine levels.
    Developmental pharmacology and therapeutics, 1992, Volume: 18, Issue:1-2

    Topics: Animals; Benzoates; Benzoic Acid; Body Weight; Carnitine; Coenzyme A Ligases; Guinea Pigs; Hippurates; Kidney; Liver; Methylprednisolone; Organ Size; Phenobarbital; Sodium Salicylate

1992
[Drug enhancement of cortisol and glucocorticoid metabolism].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Apr-10, Volume: 81, Issue:4

    Topics: Adrenal Insufficiency; Drug Interactions; Ephedrine; Half-Life; Humans; Hydrocortisone; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Rifampin

1992
Intractable cholangitis due to conduit obstruction.
    The Journal of the Arkansas Medical Society, 1990, Volume: 87, Issue:3

    Topics: Anti-Bacterial Agents; Biliary Atresia; Child; Cholangitis; Clinical Protocols; Humans; Methylprednisolone; Phenobarbital; Portoenterostomy, Hepatic; Postoperative Complications; Radionuclide Imaging

1990
Phenobarbital hepatotoxicity in an 8-month-old infant.
    Journal of hepatology, 1990, Volume: 10, Issue:2

    Topics: Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Infant; Lymphocytes; Male; Methylprednisolone; Phenobarbital; Phenytoin

1990
Effects of phenobarbitone and 6-methylprednisolone pretreatment on pressure/flow relations in the superior mesenteric and iliac arterial beds of the rat.
    The Journal of pharmacy and pharmacology, 1985, Volume: 37, Issue:3

    Topics: Animals; Blood Pressure; Iliac Artery; In Vitro Techniques; Liver; Liver Circulation; Male; Methylprednisolone; Organ Size; Perfusion; Phenobarbital; Rats; Rats, Inbred Strains; Regional Blood Flow; Splanchnic Circulation

1985
The effect of phenobarbital and methylprednisolone on the biotransformation of cyclosporine in the rat.
    Transplantation proceedings, 1988, Volume: 20, Issue:2 Suppl 2

    Topics: Animals; Biotransformation; Chromatography, High Pressure Liquid; Cyclosporins; Female; Male; Methylprednisolone; Phenobarbital; Rats; Sex Factors

1988
The in vivo cytotoxic activity of procarbazine and procarbazine metabolites against L1210 ascites leukemia cells in CDF1 mice and the effects of pretreatment with procarbazine, phenobarbital, diphenylhydantoin, and methylprednisolone upon in vivo procarba
    Cancer chemotherapy and pharmacology, 1983, Volume: 11, Issue:2

    Topics: Animals; Drug Interactions; Leukemia L1210; Male; Methylprednisolone; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Procarbazine

1983
Steroid-specific and anticonvulsant interaction aspects of troleandomycin-steroid therapy.
    The Journal of allergy and clinical immunology, 1982, Volume: 69, Issue:5

    Topics: Asthma; Dose-Response Relationship, Drug; Drug Interactions; Humans; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Troleandomycin

1982
Combined treatment with nicardipine, phenobarbital, and methylprednisolone ameliorates vasogenic brain edema.
    Acta neurochirurgica. Supplementum, 1994, Volume: 60

    Topics: Animals; Blood Proteins; Blood-Brain Barrier; Brain Edema; Brain Injuries; Drug Therapy, Combination; Evans Blue; Free Radicals; Injections, Intraperitoneal; Inulin; Lipid Peroxidation; Methylprednisolone; Nicardipine; Parietal Lobe; Phenobarbital; Rats; Rats, Sprague-Dawley; Water-Electrolyte Balance

1994
DRUGS IN THE TREATMENT OF ASTHMA.
    Canadian Medical Association journal, 1964, Jul-11, Volume: 91

    Topics: Adrenocorticotropic Hormone; Aerosols; Aminophylline; Anti-Bacterial Agents; Asthma; Child; Ephedrine; Epinephrine; Hydrocortisone; Isoproterenol; Methylprednisolone; Paraldehyde; Phenobarbital; Prednisolone; Prednisone; Tetracycline; Theophylline; Toxicology; Triamcinolone

1964
SOLUBILIZATION AND EVALUATION OF POLY-N-VINYL-5-METHYL-2-OXAZOLIDINONE BARBITURATE SYSTEMS.
    Journal of pharmaceutical sciences, 1965, Volume: 54

    Topics: Barbiturates; Chemistry, Pharmaceutical; Cimetidine; Diphenhydramine; Drug Combinations; Ibuprofen; Ketanserin; Methylprednisolone; Oxazoles; Oxazolidinones; Phenobarbital; Povidone; Research; Solubility

1965
Anticonvulsant hypersensitivity syndrome: treatment with corticosteroids and intravenous immunoglobulin.
    Southern medical journal, 2004, Volume: 97, Issue:3

    Topics: Adult; Anticonvulsants; Cross Reactions; Drug Hypersensitivity; Female; Glucocorticoids; Humans; Immunoglobulins, Intravenous; Methylprednisolone; Phenobarbital; Phenytoin; Prednisone; Syndrome

2004
Increased hepatic cytochrome P4503A activity decreases the risk of developing steroid-induced osteonecrosis in a rabbit model.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2008, Volume: 26, Issue:1

    Topics: Anesthetics, Intravenous; Animals; Antifungal Agents; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Enzyme Induction; Excitatory Amino Acid Antagonists; Female; Femur Head Necrosis; Glucocorticoids; Incidence; Itraconazole; Liver; Methylprednisolone; Midazolam; Phenobarbital; Prevalence; Rabbits; Risk Factors

2008
[Case report; drug-induced hypersensitivity syndrome following meningoencephalitis associated with human herpes virus-6].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2013, Oct-10, Volume: 102, Issue:10

    Topics: Aged; Antiviral Agents; Biomarkers; Cytokines; Diagnosis, Differential; DNA, Viral; Drug Hypersensitivity Syndrome; Ganciclovir; Herpesvirus 6, Human; Humans; Lymphocyte Activation; Male; Meningoencephalitis; Methylprednisolone; Phenobarbital; Prednisolone; Pulse Therapy, Drug; T-Lymphocytes; Valproic Acid; Virus Activation

2013
Antiepileptic Hypersensitivity Syndrome to Phenobarbital: A Case Report.
    Iranian journal of allergy, asthma, and immunology, 2019, Oct-23, Volume: 18, Issue:5

    Topics: Anticonvulsants; Child, Preschool; Drug Hypersensitivity Syndrome; Female; Humans; Immunoglobulins, Intravenous; Methylprednisolone; Phenobarbital

2019