phenobarbital has been researched along with methoxyflurane in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (91.11) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (6.67) | 29.6817 |
| 2010's | 1 (2.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Furukawa, T; Karashima, D; Shigematsu, A; Takahashi, S | 1 |
| Levine, SD; Schlondorff, D; Weber, H | 1 |
| Blitt, CD; Brown, BR; Gandolfi, AJ; Sipes, IG; Wright, BJ | 1 |
| Anderson, DK; Heisey, SR; Ringer, RK | 1 |
| Caughey, GH; Kosek, JC; Mazze, RI; Rice, SA | 1 |
| Hitt, BA; Mazze, RI | 2 |
| Authier, L; Brodeur, J; Côté, MG; Geadah, D; Paquin, P; Yamauchi, M | 1 |
| Greenstein, LR; Hitt, BA; Mazze, RI | 1 |
| Adler, L; Brown, BR; Thompson, MF | 1 |
| Canova-Davis, E; Chiang, JY; Waskell, L | 1 |
| Eger, EI; Johnson, BH; Koblin, DD; Konopka, K; Waskell, L | 1 |
| Ahnefeld, FW; Beneke, G; Gostomzyk, JG; Paulini, K | 2 |
| Halsey, MJ | 1 |
| Bischoff, S; Pollard, H; Schwartz, JC | 1 |
| Clarke, KW; Hall, LW | 1 |
| Kunz, W; Schaude, G; Thomas, C | 1 |
| Fink, BR; Kenny, GE; Simpson, WE | 1 |
| Cousins, MJ; Hitt, BA; Mazze, RI | 1 |
| Cousins, MJ; Hitt, BA; Kosek, JC; Love, FV; Mazze, RI | 1 |
| Cousins, MJ; Mazze, RI | 1 |
| Van Dyke, RA | 2 |
| Brown, BR; Colella, JJ; Son, SL | 1 |
| Takahashi, S | 1 |
| Fiserova-Bergerova, V | 1 |
| Berman, ML; Bochantin, J; Hagler, K; Lowe, HJ | 1 |
| Korten, K; Van Dyke, RA | 1 |
| Van Dyke, RA; Wood, CL | 1 |
| Barr, GA; Cousins, MJ; Hitt, BA; Kosek, JC; Mazze, RI | 1 |
| Brown, BR; Sagalyn, AM | 1 |
| Bischoff, D; Dreyer, C; Göthert, M | 1 |
| Albert, DM; Bullock, JD | 1 |
| Furukawa, T; Shigematsu, A; Takahashi, S | 1 |
| Döring, HJ; Olbrisch, RR | 2 |
| Dooley, JR; Mazze, RI; Rice, SA | 1 |
| Poppers, PJ | 1 |
| Baden, JM; Mazze, RI; Rice, SA | 1 |
| Mackenroth, T; Siegers, CP; Younes, M | 1 |
| Kharasch, ED; Liggitt, HD; Park, SB; Schroeder, JL; Sheffels, P; Whittington, D | 1 |
4 review(s) available for phenobarbital and methoxyflurane
| Article | Year |
|---|---|
Methoxyflurane metabolism.
Topics: Anesthesia, Inhalation; Biotransformation; Humans; Kidney; Kinetics; Methoxyflurane; Phenobarbital | 1976 |
Renal toxicity of anaesthetics: with specific reference to the nephrotoxicity of methoxyflurane.
Topics: Acid-Base Equilibrium; Acute Kidney Injury; Adjuvants, Anesthesia; Biotransformation; Enzyme Induction; Fluorides; Humans; Hydrogen-Ion Concentration; Kidney; Kidney Concentrating Ability; Methoxyflurane; Oxalates; Phenobarbital; Prospective Studies; Time Factors | 1973 |
Biotransformation of volatile anaesthetics with special emphasis on the role of metabolism in the toxicity of anaesthetics.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Biotransformation; Chloroform; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethyl Ethers; Halothane; Humans; Kidney; Liver; Liver Circulation; Methoxyflurane; Oxalates; Phenobarbital; Rats | 1973 |
Hepatic drug metabolism and anesthesia.
Topics: Acute Kidney Injury; Anesthetics; Aryl Hydrocarbon Hydroxylases; Biphenyl Compounds; Carcinogens; Cytochrome P-450 Enzyme System; Enzyme Induction; Fluorides; Halothane; Humans; Liver; Methoxyflurane; Methylcholanthrene; Phenobarbital | 1980 |
41 other study(ies) available for phenobarbital and methoxyflurane
| Article | Year |
|---|---|
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Formaldehyde formation as a metabolite of methoxyflurane.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Formaldehyde; Haplorhini; Male; Methoxyflurane; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Rabbits; Rats | 1977 |
Inhibition of adenylate cyclase by general anesthetics in toad urinary bladder.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Animals; Bufo marinus; Cell Membrane Permeability; Cyclic AMP; Female; Methohexital; Methoxyflurane; Phenobarbital; Urinary Bladder | 1979 |
Pulmonary biotransformation of methoxyflurane: an in-vitro study in the rabbit.
Topics: Animals; Biotransformation; Cytochrome c Group; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Female; Halothane; Lung; Male; Methoxyflurane; Microsomes; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rabbits | 1979 |
Effects of anesthetics and cerebrospinal fluid potassium and calcium concentrations on the chicken cardiovascular system.
Topics: Anesthesia, Inhalation; Animals; Blood Pressure; Calcium; Cerebral Ventricles; Chickens; Female; Heart Rate; Methoxyflurane; Perfusion; Phenobarbital; Potassium | 1975 |
Effect of phenytoin (DPH) treatment on methoxyflurane metabolism in rats.
Topics: Anesthetics; Animals; Drug Interactions; Enflurane; Ethers; Fluorides; Hydrocarbons, Fluorinated; In Vitro Techniques; Isoflurane; Kidney; Kinetics; Liver; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Phenytoin; Rats | 1979 |
Effect of enzyme induction on nephrotoxicity of halothane-related compounds.
Topics: Anesthetics; Animals; Biotransformation; Enflurane; Environmental Exposure; Enzyme Induction; Fluorides; Halothane; Humans; Isoflurane; Kidney Diseases; Methoxyflurane; Phenobarbital; Rats | 1977 |
Influence of phenobarbital pretreatment on methoxyflurane and sodium fluoride nephropathy in Fischer 344 Rats.
Topics: Animals; Fluorides; Kidney Diseases; Male; Methoxyflurane; Phenobarbital; Rats; Rats, Inbred F344 | 1976 |
Metabolism in vitro of enflurane, isoflurane, and methoxyflurane.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Chemical Phenomena; Chemistry; Enzyme Induction; Ethers; Hydrocarbons, Fluorinated; Hydrocarbons, Halogenated; In Vitro Techniques; Methoxyflurane; Methyl Ethers; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred F344 | 1975 |
Kinetics of methoxyflurane biotransformation with reference to substrate inhibition.
Topics: Anesthesia, Inhalation; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Induction; Fluorides; In Vitro Techniques; Kinetics; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344 | 1976 |
Obligatory role of cytochrome b5 in the microsomal metabolism of methoxyflurane.
Topics: Animals; Cytochrome b Group; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Dealkylation; Immunoglobulin G; Male; Methoxyflurane; Microsomes, Liver; NAD; Phenobarbital; Rabbits | 1985 |
I-653 resists degradation in rats.
Topics: Anesthetics; Animals; Biotransformation; Desflurane; Drug Interactions; Ethanol; Fluorides; Halothane; Isoflurane; Methoxyflurane; Phenobarbital; Rats; Rats, Inbred Strains | 1988 |
[Alteration of the liver after application of phenobarbital and methoxyflurane (penthrane) (author's transl)].
Topics: Animals; Liver; Male; Methoxyflurane; Organ Size; Phenobarbital; Proteins; Rats; RNA | 1972 |
The metabolic breakdown of inhalation anaesthetics and their clinical implications.
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Disulfiram; Dogs; Ethers; Halothane; Humans; Kidney; Liver; Methoxyflurane; Phenobarbital; Time Factors | 1973 |
Decreased histamine synthesis in the rat brain by hypnotics and anaesthetics.
Topics: Anesthetics; Animals; Brain; Chloral Hydrate; Histamine; Hypnotics and Sedatives; Male; Methoxyflurane; Pentobarbital; Phenobarbital; Rats; Tritium | 1973 |
Spectral analysis as a method of quantitative interpretation of Doppler-shift signals.
Topics: Angiography; Animals; Benzene Derivatives; Blood Flow Velocity; Cardiac Output; Doppler Effect; Dye Dilution Technique; Halothane; Hexamethonium Compounds; Horses; Methoxyflurane; Phenobarbital; Physical Phenomena; Physics; Pulmonary Artery; Rheology; Sheep; Spectrum Analysis; Transducers; Ultrasonics; Ultrasonography | 1974 |
[The effect of phenobarbital and halogenated hydrocarbons on nitrosamine carcinogenesis].
Topics: Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Hepatocellular; Drug Synergism; Halothane; Hemangioendothelioma; Hydrocarbons, Halogenated; Kidney; Liver; Liver Neoplasms; Lung; Methoxyflurane; Mice; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Spleen; Stomach | 1969 |
Anesthetic potency compared with intensity of effect on oxygen consumption in monolayer cultures.
Topics: Amobarbital; Anesthetics; Anesthetics, Local; Animals; Barbiturates; Chloroform; Culture Techniques; Dibucaine; Ethers; Ethyl Ethers; Halothane; Lidocaine; Methohexital; Methoxyflurane; Mice; Oxygen Consumption; Phenobarbital; Prilocaine; Procaine; Secobarbital; Tetracaine; Thiamylal; Thiopental | 1968 |
Effect of enzyme induction with phenobarbital on the in vivo and in vitro defluorination of isoflurane and methoxyflurane.
Topics: Animals; Enzyme Induction; Ethers; Fluorides; Fluorine; Hydrocarbons, Fluorinated; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors | 1974 |
The etiology of methoxyflurane nephrotoxicity.
Topics: Animals; Fluorides; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Liver; Male; Methoxyflurane; Microscopy, Electron; Mitochondria; Mitochondrial Swelling; Osmolar Concentration; Oxalates; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1974 |
The effect of phenobarbitone on the metabolism of methoxyflurane to oxalic acid in the rat.
Topics: Analysis of Variance; Animals; Biotransformation; Creatinine; Enzyme Induction; Liver; Male; Methoxyflurane; Oxalates; Phenobarbital; Rats; Spectrophotometry | 1972 |
[Effect of inhalational anesthetics on hepatic microsomal enzymes (oxidative drug metabolizing enzymes)].
Topics: Anesthesia, Inhalation; Anesthetics; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Halothane; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Rats | 1972 |
[Studies in rats following mulitple single and combined administration of phenobarbitone and methoxyflurane (Penthrane). Gas chromatographic, biochemical and electron-microscopical studies].
Topics: Animals; Endoplasmic Reticulum; Liver; Male; Methoxyflurane; Microscopy, Electron; Mitochondria, Liver; Mitochondrial Swelling; Organ Size; Phenobarbital; Proteins; Rats; RNA | 1973 |
Changes of fluoride content in bone: an index of drug defluorination in vivo.
Topics: Anesthetics; Animals; Biotransformation; Body Weight; Bone and Bones; Chlorine; Drug Interactions; Ethanol; Ethers; Female; Fluoridation; Fluorides; Fluorine; Furans; Halothane; Hydrocarbons, Halogenated; Lethal Dose 50; Male; Methoxyflurane; Methyl Ethers; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Pregnancy; Proadifen; Rats; Time Factors | 1973 |
Uptake and elimination of methoxyflurane as influenced by enzyme induction in the rat.
Topics: Anesthesia, Inhalation; Animals; Chlorine; Drug Interactions; Enzyme Induction; Fluorides; Kidney; Liver; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Proadifen; Radioisotopes; Rats; Time Factors | 1973 |
Acute interaction of drugs. I. The effect of volatile anesthetics on the kinetics of aniline hydroxylase and aminopyrine demethylase in rat hepatic microsomes.
Topics: Aminopyrine N-Demethylase; Anesthetics; Aniline Compounds; Animals; Chloroform; Enzyme Induction; Ethyl Ethers; Halothane; In Vitro Techniques; Kinetics; Male; Methoxyflurane; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Rats | 1973 |
Metabolism of methoxyflurane: release of inorganic fluoride in human and rat hepatic microsomes.
Topics: Animals; Biotransformation; Chlorine; Enzyme Induction; Fluorides; Formaldehyde; Humans; Hydrogen-Ion Concentration; Male; Methoxyflurane; Methylcholanthrene; Microsomes, Liver; Nitrous Oxide; Phenobarbital; Rats; Tetracycline | 1973 |
A comparison of the renal effects and metabolism of enflurane and methoxyflurane in Fischer 344 rats.
Topics: Anesthetics; Animals; Blood Gas Analysis; Enzyme Induction; Fluorides; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Kidney; Kidney Concentrating Ability; Male; Methoxyflurane; Methyl Ethers; Microscopy, Electron; Osmolar Concentration; Phenobarbital; Potassium; Rats; Rats, Inbred Strains; Sodium; Statistics as Topic; Time Factors; Vasopressins | 1974 |
Hepatic microsomal enzyme induction by inhalation anesthetics: mechanism in the rat.
Topics: Anesthesia, Inhalation; Animals; Biotransformation; Body Weight; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Enzyme Induction; Ethyl Ethers; Female; Liver; Male; Methoxyflurane; Microsomes, Liver; Organ Size; Phenobarbital; Proteins; Rats; Starvation; Triglycerides | 1974 |
Effects of methoxyflurane anesthesia on adrenal medullary catecholamine secretion: inhibition of spontaneous secretion and secretion evoked by splanchnic-nerve stimulation.
Topics: Acid-Base Equilibrium; Adrenal Medulla; Anesthesia, Inhalation; Animals; Blood Pressure; Catecholamines; Electric Stimulation; Epinephrine; Halothane; Hemodynamics; Methoxyflurane; Norepinephrine; Oxygen; Phenobarbital; Splanchnic Nerves | 1974 |
Generalized oxalosis with retinal involvement following methoxyflurane anesthesia.
Topics: Acute Kidney Injury; Anesthesia, General; Biopsy; Calcium; Humans; Kidney; Male; Metabolic Diseases; Methoxyflurane; Microscopy, Electron; Middle Aged; Oxalates; Pentobarbital; Phenobarbital; Retina; Retinal Diseases; Time Factors | 1974 |
[Mixed function oxidation and lipid peroxidation in the liver microsomes--in relationship with metabolism of anesthetics].
Topics: Animals; Halothane; In Vitro Techniques; Lipid Metabolism; Methoxyflurane; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats | 1974 |
[Electrocorticogram, steady potential of the brain and energy-rich phosphate fractions of the cerebral cortex during anesthetic overdosage, ischemia and cyanide poisoning].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Anesthetics; Animals; Cerebral Cortex; Chloral Hydrate; Chlorobutanol; Cyanides; Depression, Chemical; Electroencephalography; Ethers; Female; Guinea Pigs; Hexobarbital; Ischemia; Male; Membrane Potentials; Methoxyflurane; Pentobarbital; Phenobarbital; Phosphates; Phosphocreatine; Propanidid; Rats; Urethane | 1970 |
[Behavior of energy-rich phosphates in the cerebral cortex during elimination of electrical activity by high doses of various anesthetics].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Blood Pressure; Cats; Cerebral Cortex; Chloral Hydrate; Electroencephalography; Electrophysiology; Guinea Pigs; Heart Rate; Hexobarbital; Methoxyflurane; Pentobarbital; Phenobarbital; Phenylacetates; Phosphates; Phosphocreatine; Rats; Respiration, Artificial; Urethane | 1968 |
Metabolism of volatile anesthetics. 3. Induction of microsomal dechlorinating and ether-cleaving enzymes.
Topics: Animals; Carbon Dioxide; Enzyme Induction; Halothane; In Vitro Techniques; Liver; Methoxyflurane; Methylcholanthrene; Microsomes; Phenobarbital; Rats | 1966 |
Metabolism by rat hepatic microsomes of fluorinated ether anesthetics following ethanol consumption.
Topics: Anesthetics; Animals; Cytochrome P-450 Enzyme System; Energy Intake; Enflurane; Ethanol; Ethers; Male; Methoxyflurane; Methyl Ethers; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344; Sevoflurane | 1983 |
Deuterated methoxyflurane anesthesia and renal function in Fischer 344 rats.
Topics: Anesthesia; Animals; Deuterium; Enzyme Induction; Fluorides; Kidney; Kidney Diseases; Male; Methoxyflurane; Phenobarbital; Rats; Rats, Inbred F344 | 1982 |
[Inhibition and acceleration of the metabolism of enflurane and methoxyflurane in rats (author's transl)].
Topics: Animals; DDT; Dimethyl Sulfoxide; Drug Interactions; Enflurane; Ethanol; Half-Life; Male; Maleates; Methoxyflurane; Phenobarbital; Rats; Rifampin | 1981 |
New insights into the mechanism of methoxyflurane nephrotoxicity and implications for anesthetic development (part 1): Identification of the nephrotoxic metabolic pathway.
Topics: Anesthetics, Inhalation; Animals; Biotransformation; GABA Modulators; Kidney Diseases; Kidney Function Tests; Liver; Male; Methoxyflurane; Phenobarbital; Rats; Rats, Inbred F344 | 2006 |