Compounds > phenobarbital

phenobarbital and methoxsalen

phenobarbital has been researched along with methoxsalen in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chambers, MA; Gelboin, HV; Gerber, N; Hilliard, JB; Mays, DC; Park, SS; Wong, DD1
Gerber, N; Hilliard, JB; Mays, DC; Wong, DD1
Gerber, N; Guiler, RC; Hecht, S; Mays, DC; Rogers, SL; Sharp, DE1
DICKEY, RF; HARTMAN, DL1
Florek-Luszczki, M; Glensk, M; Glowniak, K; Luszczki, JJ; Pyrka, D; Skalicka-Wozniak, K; Zagaja, M1

Reviews

1 review(s) available for phenobarbital and methoxsalen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for phenobarbital and methoxsalen

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Bioactivation of 8-methoxypsoralen and irreversible inactivation of cytochrome P-450 in mouse liver microsomes: modification by monoclonal antibodies, inhibition of drug metabolism and distribution of covalent adducts.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Antibodies, Monoclonal; Benzoflavones; beta-Naphthoflavone; Binding Sites; Cells, Cultured; Cysteine; Cytochrome P-450 Enzyme System; Flavonoids; Lysine; Male; Methoxsalen; Mice; Microsomes, Liver; Phenobarbital

1990
Activation of 8-methoxypsoralen by cytochrome P-450. Enzyme kinetics of covalent binding and influence of inhibitors and inducers of drug metabolism.
    Biochemical pharmacology, 1989, May-15, Volume: 38, Issue:10

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 Enzyme System; Kinetics; Methoxsalen; Microsomes, Liver; Phenobarbital; Protein Binding; Pyridines; Rats; Rats, Inbred Strains

1989
In vitro metabolism of 8-methoxypsoralen.
    Proceedings of the Western Pharmacology Society, 1984, Volume: 27

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; In Vitro Techniques; Kinetics; Male; Methoxsalen; Mice; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains

1984
PHOTODERMATITIS INDUCED BY DRUGS. II. PHOTODERMATITIS MEDICAMENTOSA.
    Skin, 1964, Volume: 3

    Topics: Anti-Bacterial Agents; Benzoates; Chlorothiazide; Diphenhydramine; Drug Eruptions; Estrogens; Geriatrics; Humans; Hypoglycemic Agents; Metals; Methoxsalen; Pharmacology; Phenobarbital; Phenothiazines; Phenylbutazone; Photosensitivity Disorders; Porphyrins; Procaine; Quinine; Riboflavin; Salicylates; Stilbamidines; Sulfonamides; Sunburn; Toxicology

1964
Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
    Fitoterapia, 2015, Volume: 105

    Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Male; Methoxsalen; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid

2015