phenobarbital has been researched along with methimazole in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (44.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Alexander, WD; Evered, DC; Lees, JF; Lewis, M | 1 |
| Crile, G; Gilliland, PF; Ibarra, JD; Peake, RL; Petty, FC; Roberts, JW | 1 |
| Zbinden, G | 1 |
| Benes, L; Stefek, M; Zelník, V | 1 |
| Hanzlik, RP; Traiger, GJ; Vyas, KP | 1 |
| Kuroiwa, Y; Yamada, Y; Yamamoto, T; Yoshida, T | 1 |
| Kammerer, RC; Lampe, MA | 1 |
| Alexander, WD; Lees, JF | 2 |
| Kallee, E | 1 |
| Bohner, J; Kallee, E; Mallet, D; Secker, KH; Wahl, R | 1 |
| Jefcoate, CR; Larsen, MC | 1 |
| Ganem, LG; Jefcoate, CR | 1 |
| Anderson, A; Ganem, LG; Jefcoate, CR; Trottier, E | 1 |
| Inoue, Y; Kurata, Y; Makinodan, F; Tanaka, K; Wako, Y | 1 |
| Bergström, U; Brittebo, EB; Fernández, EL; Franzén, A; Lang, M; Piras, E; Raffalli-Mathieu, F | 1 |
| Damani, LA; Nnane, IP | 1 |
| Fukuda, T; Ohara, A; Sumida, K; Suzuki, N; Yamada, F | 1 |
1 review(s) available for phenobarbital and methimazole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
24 other study(ies) available for phenobarbital and methimazole
| Article | Year |
|---|---|
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Role of TSH in the changes in thyroidal metabolism of [35S]methimazole in phenobarbital and thyroxine-treated rats.
Topics: Animals; Methimazole; Phenobarbital; Rats; Rats, Inbred Strains; Thyroid Gland; Thyrotropin; Thyroxine | 1977 |
Treatment of hyperthyroidism. Panel discussion.
Topics: Adolescent; Adult; Child; Female; Guanethidine; Humans; Hyperthyroidism; Iodine Radioisotopes; Male; Methimazole; Phenobarbital; Propranolol; Propylthiouracil; Reserpine; Thyroidectomy | 1975 |
Evaluation of thyroid gland activity by hormone assays and flow cytometry in rats.
Topics: Animals; Antithyroid Agents; Cell Cycle; Flow Cytometry; Male; Methimazole; Phenobarbital; Phenylenediamines; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine | 1988 |
N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent: the role of flavin-containing monooxygenase.
Topics: Animals; Anti-Arrhythmia Agents; Flavins; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Male; Methimazole; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Oxygen; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains | 1989 |
Effect of inhibitors of alpha-naphthylisothiocyanate-induced hepatotoxicity on the in vitro metabolism of alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Aminopyrine; Animals; Bilirubin; Biotransformation; Chromatography, Gas; Ditiocarb; Ethionamide; Hyperbilirubinemia; Imidazoles; Kinetics; Male; Methimazole; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Thiocyanates | 1985 |
Metabolism of deprenyl, a selective monoamine oxidase (MAO) B inhibitor in rat: relationship of metabolism to MAO-B inhibitory potency.
Topics: Amphetamine; Animals; Chromatography, Gas; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxylation; In Vitro Techniques; Male; Methamphetamine; Methimazole; Methylcholanthrene; Microsomes, Liver; Monoamine Oxidase Inhibitors; Phenethylamines; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Selegiline | 1986 |
Cytochrome P-450 dependent binding of methapyrilene to DNA in vitro.
Topics: Acetylcysteine; Aminopyridines; Animals; Biotransformation; Cattle; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; DNA; Methapyrilene; Methimazole; Metyrapone; Microsomes, Liver; NADP; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Proadifen; Rats; Safrole | 1987 |
Effect of phenobarbitone on metabolism of methimazole.
Topics: Animals; Drug Interactions; Humans; Male; Methimazole; Phenobarbital; Rats; Sulfur Isotopes; Thyroid Gland | 1973 |
[Therapy of thyroid crises].
Topics: Aspirin; Ergoloid Mesylates; Fever; Fructose; Humans; Iodine; Magnesium; Meperidine; Methimazole; Phenobarbital; Pneumonia; Prednisolone; Promethazine; Thyroid Crisis; Vitamin B 12 | 1974 |
[Thyrotoxic crisis: symptoms and therapy (author's transl)].
Topics: Adult; Aged; Ascorbic Acid; Body Temperature; Contrast Media; Female; First Aid; Germany, West; Humans; Iodides; Iodine; Male; Methimazole; Middle Aged; Phenobarbital; Prednisolone; Tachycardia; Thyroid Crisis; Triiodothyronine | 1973 |
The effect of phenobarbital on the metabolism of methinazole in the rat.
Topics: Animals; Biotransformation; Half-Life; Liver; Male; Methimazole; Oxidation-Reduction; Phenobarbital; Rats; Sulfur Radioisotopes; Thyroid Gland; Time Factors | 1974 |
Phenobarbital induction of CYP2B1, CYP2B2, and CYP3A1 in rat liver: genetic differences in a common regulatory mechanism.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Hypophysectomy; Male; Methimazole; Microsomes, Liver; Mixed Function Oxygenases; Orchiectomy; Ovariectomy; Phenobarbital; Rats; Rats, Inbred F344; Rats, Inbred WF; Sex Characteristics; Species Specificity; Steroid Hydroxylases; Testosterone | 1995 |
Endocrine factors modulate the phenobarbital-mediated induction of cytochromes P450 and phase II enzymes in a similar strain-dependent manner.
Topics: Animals; Blotting, Western; Cytochrome P-450 Enzyme System; Diet; DNA Probes; Endocrine Glands; Enzyme Induction; Female; Hormone Antagonists; Hypnotics and Sedatives; Inactivation, Metabolic; Isoenzymes; Male; Methimazole; Phenobarbital; Radioimmunoassay; Rats; Rats, Inbred F344; Rats, Wistar; Species Specificity; Thyroid Hormones | 1998 |
Phenobarbital induction of CYP2B1/2 in primary hepatocytes: endocrine regulation and evidence for a single pathway for multiple inducers.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hormones; Liver; Methimazole; Mitotane; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Rats, Inbred WF; Species Specificity; Steroid Hydroxylases; Thyroid Hormones | 1999 |
Thyroid hyperactivity induced by methimazole, spironolactone and phenobarbital in marmosets (Callithrix jacchus): histopathology, plasma thyroid hormone levels and hepatic T4 metabolism.
Topics: Animals; Anticonvulsants; Antithyroid Agents; Biopsy; Callithrix; Cytochrome P-450 Enzyme System; Immunohistochemistry; Liver; Male; Methimazole; Microscopy, Electron; Mineralocorticoid Receptor Antagonists; Phenobarbital; Radioimmunoassay; Spironolactone; Thyroid Diseases; Thyroid Gland; Thyroxine; Triiodothyronine | 2000 |
Cell-specific expression of CYP2A5 in the mouse respiratory tract: effects of olfactory toxicants.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Environmental Pollutants; Enzyme Induction; Female; Immunohistochemistry; In Situ Hybridization; Male; Methimazole; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Nasolacrimal Duct; Nitriles; Olfactory Mucosa; Phenobarbital; Pyrazoles; Respiratory System; Salivary Glands | 2003 |
Determination of the sulphoxides and sulphones of three simple sulphides in rat urine: effects of phenobarbitone, beta-naphthoflavone and methimazole.
Topics: Animals; beta-Naphthoflavone; Chlorobenzenes; Chromatography, Gas; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Male; Methimazole; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Rats; Rats, Wistar; Sulfides; Sulfones; Sulfoxides | 2005 |
Specific alteration of gene expression profile in rats by treatment with thyroid toxicants that inhibit thyroid hormone synthesis.
Topics: Animals; Antithyroid Agents; Enzyme Induction; Gene Expression Profiling; Iodide Peroxidase; Liver; Male; Methimazole; Microarray Analysis; Phenobarbital; Propylthiouracil; Rats, Wistar; Thyroid Gland; Thyroid Hormones; Transcriptome | 2018 |