phenobarbital and metallothionein

phenobarbital has been researched along with metallothionein in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's5 (41.67)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chan, HM; Cherian, MG; Tabarrok, R; Tamura, Y1
Min, KS; Onosaka, S; Tanaka, K; Terano, Y1
Ariyoshi, T; Arizono, K; Hasegawa, H; Matsumoto, H1
Della Porta, G; Dragani, TA; Manenti, G1
Waalkes, MP; Ward, JM1
Atkins, LM; Fody, EP; Gale, GR; Smith, AB; Walker, EM1
Cagen, SZ; Klaassen, CD1
Bars, RG; Henderson, CJ; Parker, MG; Smith, G; White, R; Wolf, CR1
Santoni-Rugiu, E; Thorgeirsson, SS1
Sanders, S; Thorgeirsson, SS1
Chakraborty, T; Chatterjee, A; Chatterjee, M; Saralaya, MG1
Chakraborty, T; Chatterjee, A; Chatterjee, M; Damodaran, S; Rana, A; Srivastawa, S1

Other Studies

12 other study(ies) available for phenobarbital and metallothionein

ArticleYear
The relative importance of glutathione and metallothionein on protection of hepatotoxicity of menadione in rats.
    Chemico-biological interactions, 1992, Sep-28, Volume: 84, Issue:2

    Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Calcium; Chemical and Drug Induced Liver Injury; Cytosol; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Metallothionein; Methionine Sulfoximine; Phenobarbital; Potassium; Rats; Rats, Sprague-Dawley; Sulfates; Vitamin K; Zinc; Zinc Sulfate

1992
Induction of metallothionein synthesis by menadione or carbon tetrachloride is independent of free radical production.
    Toxicology and applied pharmacology, 1992, Volume: 113, Issue:1

    Topics: Animals; Carbon Tetrachloride; Free Radicals; Lipid Peroxidation; Liver; Male; Metallothionein; Mice; Phenobarbital; Vitamin E; Vitamin K

1992
Effects of surfactants on the contents of metallothionein, heme and hemoproteins and on the activities of heme oxygenase and drug-metabolizing enzymes in rats pretreated with phenobarbital or beta-naphthoflavone.
    Bulletin of environmental contamination and toxicology, 1991, Volume: 46, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Liver; Male; Metallothionein; Mixed Function Oxygenases; Phenobarbital; Proteins; Rats; Rats, Inbred Strains; Surface-Active Agents; Zinc

1991
Effects of phenobarbital and 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene on differentiated functions in mouse liver.
    Chemico-biological interactions, 1987, Volume: 64, Issue:1-2

    Topics: Animals; Cell Differentiation; Female; gamma-Glutamyltransferase; Glucocorticoids; Glucose-6-Phosphatase; Liver; Metallothionein; Mice; Mice, Inbred C3H; Phenobarbital; Pyridines; RNA; Transcription, Genetic; Tyrosine Transaminase

1987
Induction of hepatic metallothionein in male B6C3F1 mice exposed to hepatic tumor promoters: effects of phenobarbital, acetaminophen, sodium barbital, and di(2-ethylhexyl) phthalate.
    Toxicology and applied pharmacology, 1989, Sep-01, Volume: 100, Issue:2

    Topics: Acetaminophen; Animals; Barbital; Cadmium; Carcinogens; Chromatography, Gel; Cytosol; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Liver; Male; Metallothionein; Mice; Phenobarbital; Phthalic Acids; Zinc

1989
Effects of acetaminophen on cadmium metabolism in mice.
    Toxicology and applied pharmacology, 1986, Volume: 82, Issue:2

    Topics: Acetaminophen; Animals; Body Burden; Cadmium; Chromatography, Gel; Cysteine; Feces; Kidney; Liver; Male; Metallothionein; Mice; Phenobarbital

1986
Binding of glutathione-depleting agents to metallothionein.
    Toxicology and applied pharmacology, 1980, Jun-30, Volume: 54, Issue:2

    Topics: Alkylation; Animals; Cytosol; Glutathione; In Vitro Techniques; Inactivation, Metabolic; Iodoacetates; Liver; Male; Metalloproteins; Metallothionein; Phenobarbital; Rats; Zinc

1980
1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene, an extremely potent modulator of mouse hepatic cytochrome P-450 gene expression.
    The Biochemical journal, 1993, Feb-01, Volume: 289 ( Pt 3)

    Topics: Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Gene Expression Regulation, Enzymologic; Liver; Male; Metallothionein; Mice; Mice, Inbred DBA; Microsomes, Liver; Oxazines; Phenobarbital; Protein Biosynthesis; Proteins; Pyridines; Recombinant Fusion Proteins; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Transcription, Genetic; Transfection

1993
Transgenic mouse models in carcinogenesis: interaction of c-myc with transforming growth factor alpha and hepatocyte growth factor in hepatocarcinogenesis.
    British journal of clinical pharmacology, 1996, Volume: 42, Issue:1

    Topics: Albumins; Animals; Disease Models, Animal; Female; Genes, myc; Hepatocyte Growth Factor; Liver Neoplasms, Experimental; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Phenobarbital; Transforming Growth Factor alpha

1996
Promotion of hepatocarcinogenesis by phenobarbital in c-myc/TGF-alpha transgenic mice.
    Molecular carcinogenesis, 2000, Volume: 28, Issue:3

    Topics: Animals; Apoptosis; bcl-X Protein; Carcinogens; Cell Transformation, Neoplastic; Crosses, Genetic; Genes, myc; Genes, Synthetic; Genetic Predisposition to Disease; Humans; Liver Neoplasms, Experimental; Metallothionein; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neoplasm Proteins; Phenobarbital; Precancerous Conditions; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor alpha; Transgenes

2000
Chemopreventive effect of vanadium in a rodent model of chemical hepatocarcinogenesis: reflections in oxidative DNA damage, energy-dispersive X-ray fluorescence profile and metallothionein expression.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2006, Volume: 11, Issue:7

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cell Transformation, Neoplastic; Chemoprevention; Deoxyguanosine; Diethylnitrosamine; Disease Models, Animal; DNA Damage; Elements; Liver; Liver Neoplasms, Experimental; Male; Metallothionein; Phenobarbital; Rats; Rats, Sprague-Dawley; Spectrometry, X-Ray Emission; Vanadium

2006
Cell proliferation and hepatocarcinogenesis in rat initiated by diethylnitrosamine and promoted by phenobarbital: potential roles of early DNA damage and liver metallothionein expression.
    Life sciences, 2007, Jul-19, Volume: 81, Issue:6

    Topics: Animals; Antimetabolites; Bromodeoxyuridine; Carcinogens; Cell Proliferation; Copper; Diethylnitrosamine; DNA Damage; DNA Helicases; Ki-67 Antigen; Liver; Liver Neoplasms; Male; Metallothionein; Phenobarbital; Rats; Rats, Sprague-Dawley; Spectrophotometry, Atomic; Zinc

2007