Compounds > phenobarbital

phenobarbital and medroxyprogesterone

phenobarbital has been researched along with medroxyprogesterone in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's0 (0.00)18.2507
2000's3 (18.75)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Rautio, A; Saarni, HU; Sotaniemi, EA; Stenbäck, F; Stengård, J1
Saarni, HU; Sotaniemi, EA; Stengård, JH1
Kärki, NT; Keinänen, K; Saarni, HU; Sotaniemi, EA; Stenbäck, F; Stengård, JH1
Quan, L; Riley, S; Rowe, J; Sadoff, L1
Altman, K; Gordon, GG; Southren, AL; Vittek, J; Wilker, S1
Meyer, RK; Ying, SY1
Pelkonen, RO; Puukka, M; Sotaniemi, EA1
Kärki, NT; Rautio, A; Saarni, HU; Sotaniemi, EA1
Stengård, JH1
Arranto, AJ; Keinänen, K; Kerola, T; Saarni, HU; Sotaniemi, EA; Stengård, JH; Sutinen, S1
Arranto, AJ; Rautio, A; Sotaniemi, EA1
Luoma, PV; Pelkonen, RO; Rautio, A; Sotaniemi, EA1

Reviews

1 review(s) available for phenobarbital and medroxyprogesterone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for phenobarbital and medroxyprogesterone

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Reversibility of rat liver cirrhosis by medroxyprogesterone acetate.
    Toxicologic pathology, 1989, Volume: 17, Issue:1 Pt 1

    Topics: Animals; Carbon Tetrachloride Poisoning; Immunohistochemistry; Liver; Liver Cirrhosis, Experimental; Male; Medroxyprogesterone; Microscopy, Electron; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains

1989
Medroxyprogesterone acetate (MPA) enhances liver NADPH-generating enzyme activities in normal rats.
    General pharmacology, 1988, Volume: 19, Issue:3

    Topics: Animals; Glucosephosphate Dehydrogenase; Isocitrate Dehydrogenase; Liver; Malate Dehydrogenase; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; NADP; NADPH-Ferrihemoprotein Reductase; Organ Size; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains

1988
Medroxyprogesterone acetate and phenobarbital induce NADPH producing enzyme activities in rats with a chemical liver injury.
    Research communications in chemical pathology and pharmacology, 1985, Volume: 50, Issue:1

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chemical and Drug Induced Liver Injury; Dimethylnitrosamine; Enzyme Induction; Glucose-6-Phosphatase; Isocitrate Dehydrogenase; Malate Dehydrogenase; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; NADP; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Rats, Inbred Strains

1985
New endocrine observations in a male patient with choriocarcinoma.
    Oncology, 1974, Volume: 29, Issue:3

    Topics: Adult; Brain Neoplasms; Cerebrospinal Fluid Proteins; Choriocarcinoma; Cyclophosphamide; Dactinomycin; Dexamethasone; Diagnostic Errors; Estradiol; Humans; Hydrocortisone; Lung Neoplasms; Luteinizing Hormone; Male; Medroxyprogesterone; Methotrexate; Neoplasm Metastasis; Phenobarbital; Testosterone; Vincristine

1974
Induction of hepatic testosterone A-ring reductase by medroxyprogesterone acetate.
    Endocrinology, 1972, Volume: 90, Issue:5

    Topics: 17-Ketosteroids; Adrenal Glands; Androstanes; Animals; Carbon Isotopes; Castration; Chromatography, Paper; Chromatography, Thin Layer; Dactinomycin; Enzyme Induction; Fasting; Hydrocortisone; Liver; Male; Medroxyprogesterone; Microsomes, Liver; Oxidoreductases; Phenobarbital; Progesterone; Rats; Spectrophotometry; Testosterone; Time Factors

1972
Effect of steroids on neuropharmacologic blockade of ovulation in pregnant mare's serum (PMS)-primed immature rats.
    Endocrinology, 1969, Volume: 84, Issue:6

    Topics: 17-alpha-Hydroxypregnenolone; Androstanes; Androsterone; Animals; Depression, Chemical; Desoxycorticosterone; Estradiol; Estrone; Female; Gonadotropins, Equine; Hydrocortisone; Hydroxyprogesterones; Luteinizing Hormone; Medroxyprogesterone; Organ Size; Ovulation; Phenobarbital; Progesterone; Rats

1969
Measurement of hepatic drug-metabolizing enxyme activity in man. Comparison of three different assays.
    European journal of clinical pharmacology, 1980, Volume: 17, Issue:4

    Topics: Adult; Aged; Antipyrine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Glucaric Acid; Hepatitis; Histamine H1 Antagonists; Humans; Liver; Liver Cirrhosis; Male; Medroxyprogesterone; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Prednisolone; Rifampin

1980
Disposition of medroxyprogesterone acetate and drug metabolism activity.
    Research communications in chemical pathology and pharmacology, 1983, Volume: 39, Issue:2

    Topics: Animals; Brain; Inactivation, Metabolic; Intestinal Mucosa; Liver; Lung; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains

1983
A comparison of the effects of phenobarbital and medroxyprogesterone acetate on drug and glucose metabolism in rats with chemical liver injury.
    Research communications in chemical pathology and pharmacology, 1984, Volume: 46, Issue:1

    Topics: Animals; Dimethylnitrosamine; Glucose; Liver; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains

1984
Hepatic glucose-6-phosphatase activity in non-insulin dependent diabetics. Effect of enzyme-inducing drugs.
    Acta medica Scandinavica, 1984, Volume: 215, Issue:4

    Topics: Aged; Antipyrine; Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Enzyme Induction; Female; Glipizide; Glucose-6-Phosphatase; Humans; Liver; Liver Glycogen; Male; Medroxyprogesterone; Medroxyprogesterone Acetate; Microsomes, Liver; Middle Aged; Phenobarbital

1984
Pericellular collagen in alcoholics with liver cirrhosis.
    Research communications in chemical pathology and pharmacology, 1982, Volume: 35, Issue:1

    Topics: Adult; Antipyrine; Collagen; Humans; Liver; Liver Cirrhosis, Alcoholic; Male; Medroxyprogesterone; Metabolic Clearance Rate; Middle Aged; Phenobarbital

1982
Treatment of alcoholic cirrhosis with enzyme inducers.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:5

    Topics: Adult; Aged; Enzyme Induction; Female; Humans; Liver; Liver Cirrhosis, Alcoholic; Male; Medroxyprogesterone; Middle Aged; Pharmaceutical Preparations; Phenobarbital; Serum Albumin

1980