phenobarbital has been researched along with lomustine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Byrd, A; Finn, A; Levin, VA; Stearns, J; Weinkam, RJ | 1 |
| May, HE; Reed, DJ | 1 |
| Boose, R; May, HE; Reed, DJ | 1 |
| Ahmed, AE; Boor, PJ; Costanzi, J; el-Azhary, R; Grissom, M; Haque, A | 1 |
| Hoag, G; Rozdilsky, B; Sima, AA | 1 |
| Potter, DW; Reed, DJ | 1 |
| Ahmed, AE; el-Azhary, RA | 1 |
| Bloom, ML; Muller, PJ; Tator, CH | 1 |
| Siemann, DW | 1 |
| Litterst, CL | 1 |
| Lin, HS; Weinkam, RJ | 1 |
| Bloom, M; Muller, PJ; Tator, CH | 1 |
1 review(s) available for phenobarbital and lomustine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
14 other study(ies) available for phenobarbital and lomustine
| Article | Year |
|---|---|
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
The effect of phenobarbital pretreatment on the antitumor activity of 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU), 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) and 1-(2-chloroethyl)-3-(2,6-dioxo-3-piperidyl-1-nitrosourea (PCNU), and on the plasma p
Topics: Alkylating Agents; Animals; Biotransformation; Brain Neoplasms; Carmustine; Dexamethasone; Drug Interactions; In Vitro Techniques; Kinetics; Liver; Lomustine; Male; Methylprednisolone; Neoplasms, Experimental; Nitrosourea Compounds; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344 | 1979 |
Alkylation and carbamoylation intermediates from the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-1.
Topics: Acetates; Alkylation; Animals; Carbamates; Carbocysteine; Dicarboxylic Acids; Ethane; Ethylene Chlorohydrin; Halogens; Hydroxylation; Isomerism; Lomustine; Male; Methylcholanthrene; Microsomes; Nitrosourea Compounds; Phenobarbital; Rats; Sulfides | 1975 |
Microsomal monooxygenation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Synthesis and identification of cis and trans monohydroxylated products.
Topics: Animals; Antineoplastic Agents; Carbon Monoxide; Hydroxylation; Lomustine; Male; Methylcholanthrene; Microsomes, Liver; Nitrosourea Compounds; Oxidation-Reduction; Phenobarbital; Rats; Stereoisomerism | 1975 |
Studies on the mechanism of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-induced hepatotoxicity. II. Biochemical and morphological characterization of the injury and its prevention by phenobarbital.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Bile; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Ethylmorphine-N-Demethylase; Glucuronosyltransferase; Hyperbilirubinemia; Liver Diseases; Lomustine; Male; Phenobarbital; Rats | 1987 |
Astroblastoma revisited: a report of three cases.
Topics: Adult; Aged; Astrocytoma; Brain Neoplasms; Combined Modality Therapy; Electroencephalography; Female; Histocytochemistry; Humans; Immunochemistry; Lomustine; Male; Middle Aged; Phenobarbital; Seizures; Tomography, X-Ray Computed | 1986 |
Involvement of FMN and phenobarbital cytochrome P-450 in stimulating a one-electron reductive denitrosation of 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea catalyzed by NADPH-cytochrome P-450 reductase.
Topics: Anaerobiosis; Animals; Biotransformation; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Flavin Mononucleotide; Kinetics; Lomustine; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitrosourea Compounds; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
Heme metabolism in liver and spleen of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU)-treated rats.
Topics: 5-Aminolevulinate Synthetase; Animals; Heme; Heme Oxygenase (Decyclizing); Liver; Lomustine; Male; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains; Spleen | 1984 |
Use of phenobarbital and high doses of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in the treatment of brain tumor-bearing mice.
Topics: Animals; Brain Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Drug Interactions; Female; Lethal Dose 50; Lomustine; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosourea Compounds; Phenobarbital | 1983 |
Effect of pretreatment with phenobarbital or SKF 525A on the toxicity and antitumor activity of lomustine.
Topics: Animals; Female; Lomustine; Mice; Mice, Inbred C3H; Nitrosourea Compounds; Phenobarbital; Proadifen; Sarcoma, Experimental | 1983 |
Prolonged depression of hepatic microsomal drug metabolism and hemoprotein levels following a single dose of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU).
Topics: Animals; Cytochrome P-450 Enzyme System; Depression, Chemical; Hemeproteins; In Vitro Techniques; Lomustine; Male; Microsomes, Liver; Mixed Function Oxygenases; Nitrosourea Compounds; Phenobarbital; Rats; Time Factors | 1981 |
Metabolism of 1,3-bis(2-chloroethyl)-1-nitrosourea by rat hepatic microsomes.
Topics: Animals; Carmustine; In Vitro Techniques; Kinetics; Lomustine; Male; Microsomes, Liver; NADP; Phenobarbital; Rats; Rats, Inbred F344 | 1981 |
The effect of phenobarbital on the toxicity and tumoricidal activity of CCNU in a murine brain tumor model.
Topics: Animals; Brain Neoplasms; Drug Therapy, Combination; Ependymoma; Female; Lomustine; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nitrosourea Compounds; Phenobarbital | 1980 |