phenobarbital and lithocholic acid

phenobarbital has been researched along with lithocholic acid in 19 studies

Research

Studies (19)

Timeframe	Studies, this research(%)	All Research%
pre-1990	13 (68.42)	18.7374
1990's	2 (10.53)	18.2507
2000's	4 (21.05)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Stiehl, A	1
Hayes, JD; Percy-Robb, IW; Strange, RC	1
Drew, R; Priestly, BG	1
Czygan, P; Fröhling, W; Kommerell, B; Stiehl, A	1
Ast, E; Czygan, P; Fröhling, W; Kommerell, B; Stiehl, A	1
Bonorris, GG; Chung, A; Coyne, MJ; Goldstein, LI; Lahana, D; Schoenfield, LJ	1
Sturdevant, RA	1
Fujimoto, JM; Olson, JR; Peterson, RE	1
Denda, A; Hasegawa, K; Kitazawa, S; Konishi, Y; Maruyama, H; Tamura, K; Tsujiuchi, T; Tsutsumi, M	1
Holsztynska, EJ; Iscan, M; Lester, R; Radominska, A; Waxman, DJ; Zimniak, P	1
Kinugasa, T; Kobayashi, H; Konishi, Y; Makino, T; Obara, T; Takahashi, S; Ura, H	1
Björkhem, I; Danielsson, H; Wikvall, K	1
Schoenfield, LJ	1
Selye, H	1
Chapman, BA; Pattinson, NR	1
Beilke, LD; Besselsen, DG; Cheng, Q; Cherrington, NJ; Kulkarni, S; Slitt, AL	1
Aleksunes, LM; Beger, RD; Beilke, LD; Besselsen, DG; Cherrington, NJ; Holland, RD; Klaassen, CD	1
Aleksunes, LM; Beilke, LD; Besselsen, DG; Cherrington, NJ; Dvorak, K; Klaassen, CD; Olson, ER	1

Reviews

3 review(s) available for phenobarbital and lithocholic acid

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
Disturbances of bile acid metabolism in cholestasis. Clinics in gastroenterology, 1977, Volume: 6, Issue:1 Topics: Bile Acids and Salts; Bile Ducts; Cholestasis; Cholestyramine Resin; Deoxycholic Acid; Disease Models, Animal; Female; Glucuronates; Hepatitis; Humans; Ligation; Lithocholic Acid; Liver; Liver Cirrhosis; Male; Phenobarbital; Pregnancy; Pregnancy Complications; Sterols; Sulfates	1977
Medical therapy for gallstones. Gastroenterology, 1974, Volume: 67, Issue:4 Topics: Administration, Oral; Bile; Bile Acids and Salts; Bilirubin; Calcium; Chemical and Drug Induced Liver Injury; Chenodeoxycholic Acid; Cholelithiasis; Cholesterol; Humans; Lithocholic Acid; Liver; Phenobarbital; United States	1974

Trials

1 trial(s) available for phenobarbital and lithocholic acid

Article	Year
Treatment of gallstones with chenodeoxycholic acid and phenobarbital. The New England journal of medicine, 1975, Mar-20, Volume: 292, Issue:12 Topics: Adult; Aged; Bile; Biopsy; Chenodeoxycholic Acid; Cholelithiasis; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Lipids; Lithocholic Acid; Liver; Liver Function Tests; Male; Middle Aged; Phenobarbital	1975

Other Studies

15 other study(ies) available for phenobarbital and lithocholic acid

Article	Year
Identification of two lithocholic acid-binding proteins. Separation of ligandin from glutathione S-transferase B. The Biochemical journal, 1979, Sep-01, Volume: 181, Issue:3 Topics: Animals; Carrier Proteins; Chromatography, Ion Exchange; Cytosol; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Glutathione Transferase; Lithocholic Acid; Liver; Male; Peptide Fragments; Phenobarbital; Rats	1979
Failure of hypoactive hypertrophic smooth endoplasmic reticulum to produce cholestasis in rats. Toxicology and applied pharmacology, 1978, Volume: 45, Issue:1 Topics: Animals; Cholestasis; Cobalt; Endoplasmic Reticulum; Hypertrophy; Lithocholic Acid; Liver Function Tests; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats	1978
Induction and activation of rat liver microsomal bile salt glucuronyltransferase. Biochimica et biophysica acta, 1976, Sep-24, Volume: 444, Issue:2 Topics: Animals; Chenodeoxycholic Acid; Cholic Acids; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Hexosyltransferases; Lithocholic Acid; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Phenobarbital; Polyethylene Glycols; Rats	1976
[Induction and activation of bile acid glucuronyl transferase in rat liver microsomes]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 1 Topics: Animals; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Lithocholic Acid; Microsomes, Liver; Phenobarbital; Polyethylene Glycols; Rats	1976
Medical treatment of gallstones. Southern medical journal, 1975, Volume: 68, Issue:1 Topics: Animals; Arteriosclerosis; Bile; Chenodeoxycholic Acid; Cholelithiasis; Cholestasis; Cholesterol; Diarrhea; Humans; Lipid Metabolism; Lithocholic Acid; Liver; Macaca mulatta; Phenobarbital; Phosphatidylcholines; Placebos	1975
Measurement and alteration of the capacity of the distended biliary tree in the rat. Toxicology and applied pharmacology, 1976, Volume: 36, Issue:2 Topics: Animals; Biliary Tract; Body Weight; Cricetinae; Guinea Pigs; Lithocholic Acid; Liver; Male; Mannitol; Organ Size; Phenobarbital; Pressure; Rabbits; Rats; Time Factors	1976
Enhanced preneoplastic liver lesion development under 'selection pressure' conditions after administration of deoxycholic or lithocholic acid in the initiation phase in rats. Carcinogenesis, 1990, Volume: 11, Issue:8 Topics: Animals; Body Weight; Deoxycholic Acid; gamma-Glutamyltransferase; Glutathione Transferase; Lithocholic Acid; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344	1990
Distinct forms of cytochrome P-450 are responsible for 6 beta-hydroxylation of bile acids and of neutral steroids. The Biochemical journal, 1991, Apr-01, Volume: 275 ( Pt 1) Topics: Androstenedione; Animals; Bile Acids and Salts; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Hydroxylation; Lithocholic Acid; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344; Rats, Inbred Strains; Steroid Hydroxylases; Steroids	1991
Effects of phenobarbital and secondary bile acids on liver, gallbladder, and pancreas carcinogenesis initiated by N-nitrosobis (2-hydroxypropyl)amine in hamsters. Journal of the National Cancer Institute, 1986, Volume: 76, Issue:5 Topics: Adenoma, Bile Duct; Animals; Bile Acids and Salts; Cocarcinogenesis; Cricetinae; Deoxycholic Acid; Eating; Gallbladder Neoplasms; Lithocholic Acid; Liver Neoplasms, Experimental; Male; Mesocricetus; Nitrosamines; Organ Size; Pancreatic Neoplasms; Phenobarbital; Polyps	1986
Hydroxylations of bile acids by reconstituted systems from rat liver microsomes. The Journal of biological chemistry, 1974, Oct-25, Volume: 249, Issue:20 Topics: Animals; Bile Acids and Salts; Carbon Radioisotopes; Cattle; Chenodeoxycholic Acid; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Deoxycholic Acid; Drug Stability; Erythrocytes; Female; Freezing; Lithocholic Acid; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Phenobarbital; Phosphatidylcholines; Rats; Sex Factors; Superoxide Dismutase; Taurine; Time Factors; Tritium; Ultracentrifugation	1974
Prevention by catatoxic steroids of lithocholic acid-induced biliary concrements in the rat. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1972, Volume: 141, Issue:2 Topics: Animals; Bile Acids and Salts; Body Weight; Common Bile Duct; Female; Gallstones; Jaundice; Lithocholic Acid; Liver; Nitriles; Phenobarbital; Phenytoin; Prednisolone; Propionates; Rats; Steroids; Thyroxine; Triamcinolone; Triiodothyronine	1972
Lithocholate detoxification and biliary secretion in the rat. Biochemistry international, 1984, Volume: 9, Issue:2 Topics: Animals; Bile; Catalysis; Cytosol; Glutathione Transferase; Inactivation, Metabolic; Lithocholic Acid; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Taurocholic Acid	1984
Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis. Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 102, Issue:1 Topics: Animals; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis, Intrahepatic; Cytoprotection; Disease Models, Animal; Lithocholic Acid; Liver; Male; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Multidrug Resistance-Associated Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Dependent; Phenobarbital; Protective Agents; Pyrazines; Pyridines; RNA, Messenger; Symporters; Thiones; Thiophenes; Time Factors; Up-Regulation	2008
Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice. Drug metabolism and disposition: the biological fate of chemicals, 2009, Volume: 37, Issue:5 Topics: Animals; Bile Acids and Salts; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Constitutive Androstane Receptor; DNA; DNA-Binding Proteins; Lithocholic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Oligonucleotide Probes; Phenobarbital; Pyridines; Receptors, Cytoplasmic and Nuclear; RNA; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Transcription Factors	2009
Decreased apoptosis during CAR-mediated hepatoprotection against lithocholic acid-induced liver injury in mice. Toxicology letters, 2009, Jul-10, Volume: 188, Issue:1 Topics: Animals; Apoptosis; bcl-X Protein; Caspase 3; Cholestasis, Intrahepatic; Constitutive Androstane Receptor; Cytoprotection; Disease Models, Animal; Lithocholic Acid; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myeloid Cell Leukemia Sequence 1 Protein; Phenobarbital; Pregnenolone Carbonitrile; Proto-Oncogene Proteins c-bcl-2; Pyrazines; Pyridines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thiones; Thiophenes; Transcription Factors	2009