Compounds > phenobarbital

phenobarbital and lauric acid

phenobarbital has been researched along with lauric acid in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's4 (44.44)18.2507
2000's3 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET1
Gibson, GG; Orton, TC; Tamburini, PP1
Alterman, MA; Chaurasia, CS; Hanzlik, RP; Lu, P1
Alayrac, C; Durst, F; Mioskowski, C; Pinot, F; Salaün, JP1
Bookstaff, RC; Minnema, D; Murphy, VA; Parkinson, A; Sanzgiri, U; Skare, JA1
Fisher, MB; Guan, X; Koop, DR; Lang, DH; Rettie, AE; Zheng, YM1
Benveniste, I; Blée, E; Kandel, S; Morant, M; Pinot, F; Werck-Reichhart, D1
Draper, A; Leonard, N; Ogilvie, BW; Parkinson, A1

Reviews

1 review(s) available for phenobarbital and lauric acid

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

8 other study(ies) available for phenobarbital and lauric acid

ArticleYear
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
    Molecular pharmacology, 1985, Volume: 28, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin

1985
Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid).
    The Biochemical journal, 1982, Apr-01, Volume: 203, Issue:1

    Topics: Animals; Benzphetamine; Catalysis; Clofibrate; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Enzyme Induction; Kinetics; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1982
Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation.
    Biochemical and biophysical research communications, 1995, Sep-25, Volume: 214, Issue:3

    Topics: Animals; Clofibrate; Cytochrome P-450 Enzyme System; Enzyme Induction; Gas Chromatography-Mass Spectrometry; Hydroxylation; Isoenzymes; Lauric Acids; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Sprague-Dawley; Recombinant Fusion Proteins; Structure-Activity Relationship

1995
New cytochrome P450-dependent reactions from wheat: terminal and sub-terminal hydroxylation of oleic acid by microsomes from naphthalic acid anhydride and phenobarbital induced wheat seedlings.
    Biochemical and biophysical research communications, 1994, Jan-28, Volume: 198, Issue:2

    Topics: Cytochrome P-450 Enzyme System; Hydroxylation; Lauric Acids; Microsomes; Naphthalenes; Oleic Acid; Oleic Acids; Phenobarbital; Pyrones; Triticum

1994
Effects of doxylamine succinate on thyroid hormone balance and enzyme induction in mice.
    Toxicology and applied pharmacology, 1996, Volume: 141, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme System; Doxylamine; Enzyme Induction; Female; Histamine H1 Antagonists; Hydroxylation; Lauric Acids; Male; Mice; Microsomes, Liver; Phenobarbital; Testosterone; Thyroid Hormones

1996
Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid.
    Chemico-biological interactions, 1998, Mar-12, Volume: 110, Issue:1-2

    Topics: Acetone; Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Carcinogens; Catalysis; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Enzyme Induction; Fatty Acids, Monounsaturated; Gas Chromatography-Mass Spectrometry; Isoenzymes; Lauric Acids; Microsomes, Liver; NADP; Phenobarbital; Rabbits; Rifampin; Stereoisomerism

1998
Cloning, functional expression, and characterization of CYP709C1, the first sub-terminal hydroxylase of long chain fatty acid in plants. Induction by chemicals and methyl jasmonate.
    The Journal of biological chemistry, 2005, Oct-28, Volume: 280, Issue:43

    Topics: Acetates; Blotting, Northern; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cloning, Molecular; Cyclopentanes; Cytochrome P-450 Enzyme System; DNA, Complementary; Dose-Response Relationship, Drug; Fatty Acids; Gas Chromatography-Mass Spectrometry; Gene Library; Genome, Plant; Kinetics; Lauric Acids; Microsomes; Models, Chemical; Naphthalenes; Oxylipins; Phenobarbital; Plant Proteins; Stearic Acids; Substrate Specificity; Time Factors; Triticum

2005
On the mechanism of hepatocarcinogenesis of benzodiazepines: evidence that diazepam and oxazepam are CYP2B inducers in rats, and both CYP2B and CYP4A inducers in mice.
    Drug metabolism reviews, 2006, Volume: 38, Issue:1-2

    Topics: Animals; Benzodiazepines; Blotting, Western; Body Weight; Carcinogens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diazepam; Hypnotics and Sedatives; Immunohistochemistry; Isoenzymes; Lauric Acids; Liver Neoplasms; Male; Mice; Microsomes, Liver; Nitrophenols; Organ Size; Oxazepam; Phenobarbital; Rats; Rats, Sprague-Dawley

2006