phenobarbital has been researched along with lamotrigine in 104 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 16 (15.38) | 18.2507 |
| 2000's | 35 (33.65) | 29.6817 |
| 2010's | 45 (43.27) | 24.3611 |
| 2020's | 8 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Alexander, MS; Edafiogho, IO; Farrar, VA; Kolen, KR; Moore, JA; Rankin, GO; Scott, KR; Sims, LD; Stables, JP; Tonnu, AD | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Bianucci, AM; Calderone, V; Coi, A; Massarelli, I; Testai, L | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Karcz, T; Karolak-Wojciechowska, J; Kieć-Kononowicz, K; Kuder, K; Latacz, G; Schwed, JS; Stark, H; Łażewska, D | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Patsalos, PN; Sander, JW | 1 |
| Jones, SR; Ramachandran, S; Underhill, S | 1 |
| Boreus, L; Eriksson, AS; Hoppu, K; Nergårdh, A | 1 |
| Jürgens, U; May, TW; Rambeck, B | 1 |
| Berlinghieri, MC; David, E; De Sarro, GB; Dominijanni, A; Elia, M; Gulletta, E; Musumeci, SA | 1 |
| Anderson, GD | 1 |
| Chapman, MS; Lewis, LD; Zug, KA | 1 |
| Dutton, J; Higgins, G; Hughes, A; Roberts, NB | 1 |
| Hildebrandt, J; Paulus, W; Tergau, F; Wischer, S; Ziemann, U | 1 |
| Chen, C; Cox, E; Fiedler-Kelly, J; Grasela, TH; Risner, ME; Womble, GP | 1 |
| Böttiger, Y; Ståhle, L; Svensson, JO | 1 |
| Carvill, S; Cassidy, G; Clarke, D | 1 |
| Buoni, S; Fois, A; Grosso, S | 1 |
| Brodie, MJ | 1 |
| Albani, F; Baruzzi, AA; Contin, M; Riva, R | 1 |
| Carwile, ST; Husain, AM; Miller, PP; Radtke, RA | 1 |
| Jufer, RA; Levine, B; Smialek, JE | 1 |
| Aberg, LE; Bäckman, M; Kirveskari, E; Santavuori, P | 1 |
| Harden, CL | 1 |
| Malkiewicz, IM; Neuman, MG; Shear, NH | 1 |
| Carvalho, D; Lanças, FM; Queiroz, ME; Silva, SM | 1 |
| Albani, F; Avoni, P; Baruzzi, A; Contin, M; Riva, R | 1 |
| De Sarro, A; De Sarro, G; Di Paola, ED; Ferreri, G; Fischer, W | 1 |
| Fedrowitz, M; Löscher, W; Potschka, H | 1 |
| Baraban, SC; Barbaro, NM; Smyth, MD | 1 |
| Rekling, JC | 1 |
| Claycamp, HG; Lathers, CM; Schraeder, PL | 1 |
| Meussen-Elholm, ET; Olsen, CM; Røste, LS; Taubøll, E | 1 |
| Chiarelli, F; Cutarella, R; Giannuzzi, R; Latini, G; Morgese, G; Trotta, D; Verrotti, A | 1 |
| Papp, Z; Török, L | 1 |
| Mishchenko, AL; Morozov, GV; Semenova, NV; Slastenko, OA | 1 |
| Bode-Böger, SM; Martens-Lobenhoffer, J | 1 |
| Messenheimer, J; Mockenhaupt, M; Schlingmann, J; Tennis, P | 1 |
| Bodhankar, SL; Patil, KM | 1 |
| Cantú, MD; Carrilho, E; Lacerda, CA; Lanças, FM; Queiroz, ME; Toso, DR | 1 |
| Cooper, C; Feely, M; Hay, A; Kemp, S; Wild, H | 1 |
| Ben-Ezra, J; Massey, GV; Riley, RS; Russell, EC; Williams, DC | 1 |
| Gale, K; Katz, I; Kim, J; Kondratyev, A | 1 |
| Edelbroek, PM; Vermeij, TA | 1 |
| Rajna, P | 1 |
| Arvieux, C; Coquerel, N; Michelet, C; Nesseler, N; Polard, E; Tattevin, P | 1 |
| Ben-Ari, Y; Franco, V; Jorquera, I; Manent, JB; Perucca, E; Represa, A | 1 |
| Błaszczyk, B; Chrościńska-Krawczyk, M; Czuczwar, SJ; Jankiewicz, K | 1 |
| Bidlack, JM; Morris, HH | 1 |
| Alla, P; Bounolleau, P; de Greslan, T; Fournier, B; Ouologem, M; Renard, JL; Ricard, D; Sallansonnet-Froment, M; Taillia, H | 1 |
| Aguglia, U; Belcastro, V; Caccamo, D; Calabresi, P; Ciampa, C; Costa, C; Gorgone, G; Ientile, R; Marciani, MG; Oteri, G; Pisani, F; Pisani, LR; Striano, P; Striano, S | 1 |
| Argikar, UA; Larson, EE; Remmel, RP; Senekeo-Effenberger, K; Tukey, RH | 1 |
| Cumbo, E; Ligori, LD | 1 |
| Berger, I; Saada, A; Segal, I; Shmueli, D | 1 |
| Forcelli, PA; Gale, K; Janssen, MJ; Stamps, LA; Sweeney, C; Vicini, S | 1 |
| Lang, SY; Shi, XB; Tian, HJ; Wang, RF; Wang, XQ; Yang, F | 1 |
| Genton, P; Velizarova, R | 1 |
| Calabrò, G; De Sarro, G; Gallelli, L; Siniscalchi, A; Tolotta, GA | 1 |
| Espinosa, AG; García, VF; González, YR; Machado, RA; Melendrez, D; Rodríguez, YQ | 1 |
| Crespel, A; Gelisse, P; Genton, P; Pageaux, GP; Velizarova, R | 1 |
| de Rijke, YB; van Toor, H; Visser, TJ; Visser, WE | 1 |
| Acree, WE; Jouyban, A; Panahi-Azar, V; Shayanfar, A; Soleymani, J; York, P; Yousefi, BH | 1 |
| Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Tomson, T; Vajda, F | 2 |
| Mukhin, KIu; Sivkova, SN; Zaĭkova, FM | 1 |
| Phinney, KW; Tai, SS; Yeh, CY | 1 |
| Kotov, AS; Rudakova, IG | 1 |
| Carapella, CM; Dinapoli, L; Fabi, A; Maschio, M; Pace, A; Pompili, A; Sperati, F; Vidiri, A | 1 |
| Alexander, JM; Wilson, KL | 1 |
| Alves, G; Falcão, A; Fortuna, A; Rocha, M; Serralheiro, A | 1 |
| Chiarelli, F; Cofini, M; Scaparrotta, A; Tiboni, GM; Verrotti, A | 1 |
| Brandt, C; Löscher, W | 1 |
| Alves, G; Falcão, A; Ferreira, A; Fortuna, A; Francisco, J; Oliveira, P; Rodrigues, M; Rosado, L; Rosado, P | 1 |
| Golubović, B; Jovanović, M; Kovačević, SV; Martinović, Ž; Miljković, B; Prostran, M; Vučićević, K | 1 |
| Cheong, J; Lau, C; Watson, H | 1 |
| Abbasi, B; Asadi, M; Dadfarnia, S; Haji Shabani, AM | 1 |
| Jimeno, FJ; Manso, G; Ordoñez, L; Salgueiro, E | 1 |
| Beaud, N; Borggraefe, I; Budde, J; Debus, O; Ensslen, M; Geis, T; Gilbert, M; Haeussler, M; Hahn, A; Hehr, U; Heiming, R; Herbst, SM; Kurlemann, G; Morgner, R; Morris-Rosendahl, DJ; Muelleder, K; Philippi, H; Proepper, CR; Ross, S; Schuierer, G; Strobl-Wildemann, G; von Gersdorff, G; Vosschulte, P | 1 |
| Abe, S; Azuma, Y; Ishihara, N; Ito, Y; Itomi, K; Kidokoro, H; Kojima, S; Kurahashi, H; Kurahashi, N; Maruyama, K; Natsume, J; Negoro, T; Okumura, A; Suzuki, M; Takeuchi, T; Tsuji, T; Watanabe, K; Yamada, K; Yamamoto, H | 1 |
| Bártfai, G; Devosa, I; Szok, D; Vanya, M | 1 |
| Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS | 1 |
| Liu, J; Wang, LN; Wang, YP; Wu, LY | 2 |
| Marson, AG; Nevitt, SJ; Sudell, M; Tudur Smith, C; Weston, J | 2 |
| Battaglia, A; Carey, JC; Ho, KS; Lortz, A; Markham, LM; Newcomb, T; Olson, LM; Sheng, X; Twede, H; Wassman, ER; Weng, C | 1 |
| Kondrat-Wróbel, MW; Łuszczki, JJ | 1 |
| Battino, D; Bonizzoni, E; Craig, J; Lindhout, D; Perucca, E; Sabers, A; Thomas, SV; Tomson, T; Vajda, F | 1 |
| Hosohata, K; Inada, A; Iwanaga, K; Niinomi, I; Oyama, S; Wakabayashi, T | 1 |
| Goji, A; Imoto, I; Ito, H; Kagami, S; Kohmoto, T; Mori, K; Mori, T; Toda, Y | 1 |
| Barker-Haliski, M; Knox, KM; Koneval, Z; Memon, A; White, HS; Zierath, DK | 1 |
| Beier, CP; Gesche, J; Hjalgrim, H; Rubboli, G | 1 |
| Demir, O; Kaplan, YC | 1 |
| Liu, J; Wang, LN | 1 |
| Afshar Mogaddam, MR; Farajzadeh, MA; Jouyban, A; Khosrowshahi, EM; Nemati, M; Tuzen, M | 1 |
| Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R | 1 |
| Jiang, W; Jiang, Y; Ma, L; Shi, X; Song, C; Wang, Y; Xia, L; Zhang, Y; Zhao, J | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
21 review(s) available for phenobarbital and lamotrigine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 1994 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Population pharmacokinetics of lamotrigine adjunctive therapy in adults with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Primidone; Randomized Controlled Trials as Topic; Retrospective Studies; Triazines | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
[Effects of antiepileptic drugs on mood of people with epilepsy].
Topics: Affect; Anticonvulsants; Antidepressive Agents; Carbamazepine; Depressive Disorder; Epilepsy; Fructose; Humans; Lamotrigine; Mood Disorders; Oxcarbazepine; Patient Compliance; Phenobarbital; Psychometrics; Topiramate; Triazines; Vigabatrin | 2007 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K | 2013 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabilities; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2014 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide | 2016 |
Treatment of epilepsy for people with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anticonvulsants; Cognition; Depression; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Phenobarbital; Piracetam; Randomized Controlled Trials as Topic; Triazines | 2016 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Treatment of epilepsy for people with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anticonvulsants; Cognition; Depression; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Phenobarbital; Secondary Prevention | 2018 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2021 |
Treatment of epilepsy for people with Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Anticonvulsants; Cognition; Depression; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Phenobarbital; Randomized Controlled Trials as Topic; Secondary Prevention | 2021 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
10 trial(s) available for phenobarbital and lamotrigine
| Article | Year |
|---|---|
Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Lamotrigine; Male; Phenobarbital; Treatment Outcome; Triazines; Valproic Acid | 1996 |
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Triazines; Valproic Acid | 1996 |
Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Electric Stimulation; Ethanol; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lorazepam; Male; Motor Cortex; Neural Inhibition; Phenobarbital; Transcranial Magnetic Stimulation; Triazines; Vigabatrin | 1998 |
Lamotrigine in typical absence epilepsy.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Clonazepam; Drug Resistance; Electroencephalography; Epilepsy, Absence; Female; Humans; Lamotrigine; Male; Phenobarbital; Triazines | 1999 |
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid | 1999 |
Epilepsy and antiepileptic drug therapy in juvenile neuronal ceroid lipofuscinosis.
Topics: Adolescent; Adult; Age of Onset; Anticonvulsants; Child; Child, Preschool; Clonazepam; Comorbidity; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Finland; Follow-Up Studies; Humans; Lamotrigine; Male; Neuronal Ceroid-Lipofuscinoses; Phenobarbital; Treatment Outcome; Triazines; Valproic Acid | 2000 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
Factors associated with poor control in partial complex epilepsy.
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy, Complex Partial; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Phenobarbital; Predictive Value of Tests; Prospective Studies; Recurrence; Risk Factors; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Levetiracetam, lamotrigine, and phenobarbital in patients with epileptic seizures and Alzheimer's disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Anticonvulsants; Case-Control Studies; Cognition Disorders; Cross-Sectional Studies; Double-Blind Method; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Mental Status Schedule; Middle Aged; Neuropsychological Tests; Phenobarbital; Piracetam; Time Factors; Treatment Outcome; Triazines | 2010 |
[Efficacy of treatment of focal forms of epilepsy in children with antiepileptic drugs of different generations].
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Female; Fructose; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Phenobarbital; Topiramate; Treatment Outcome; Triazines | 2011 |
73 other study(ies) available for phenobarbital and lamotrigine
| Article | Year |
|---|---|
Synthesis and anticonvulsant activity of enaminones. 3. Investigations on 4'-, 3'-, and 2'-substituted and polysubstituted anilino compounds, sodium channel binding studies, and toxicity evaluations.
Topics: Animals; Anticonvulsants; Batrachotoxins; Kidney; Liver; Male; Mice; Rats; Rats, Inbred F344; Sodium Channels; Structure-Activity Relationship | 1995 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Identification of "toxicophoric" features for predicting drug-induced QT interval prolongation.
Topics: Amino Acid Sequence; Heart; Humans; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Subunits; Sequence Alignment; Structure-Activity Relationship; Trans-Activators; Transcriptional Regulator ERG | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Chlorophenoxy aminoalkyl derivatives as histamine H(3)R ligands and antiseizure agents.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Humans; Ligands; Male; Mice; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Histamine H3; Seizures; Structure-Activity Relationship | 2016 |
Measurement of lamotrigine under conditions measuring phenobarbitone, phenytoin, and carbamazepine using reversed-phase high-performance liquid chromatography at dual wavelengths.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamotrigine; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Triazines | 1994 |
Does antiepileptic therapy affect immune response?
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid | 1998 |
Lamotrigine and phenobarbitone-associated hypersensitivity syndrome: resolution without corticosteroids.
Topics: Aged; Anticonvulsants; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Lamotrigine; Lip Diseases; Phenobarbital; Triazines | 1998 |
The incorporation of lamotrigine into the routine automated sequential trace enrichment of dialysates assay of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Triazines | 1998 |
Lamotrigine drug interactions in a TDM material.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Triazines; Valproic Acid | 1999 |
The management of epilepsy in a hospital for people with a learning disability.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Utilization; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Hospitals, Psychiatric; Humans; Lamotrigine; Learning Disabilities; Male; Middle Aged; Phenobarbital; Triazines; United Kingdom; Vigabatrin | 1999 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Lamotrigine distribution in two postmortem cases.
Topics: Adult; Anticonvulsants; Drug Overdose; Female; Gas Chromatography-Mass Spectrometry; Humans; Lamotrigine; Middle Aged; Phenobarbital; Suicide; Tissue Distribution; Triazines | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Survival; Chemistry, Clinical; Child; Cohort Studies; Coloring Agents; Drug Hypersensitivity; Family Health; Female; HIV Seropositivity; Humans; Lamotrigine; Lymphocytes; Male; Mice; Microsomes, Liver; Middle Aged; Mitochondria; Phenobarbital; Phenytoin; Sensitivity and Specificity; Succinate Dehydrogenase; Sulfadiazine; Sulfamethoxazole; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Triazines; Trimethoprim; Trypan Blue | 2000 |
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Lamotrigine; Phenobarbital; Phenytoin; Primidone; Triazines | 2002 |
Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Atenolol; Body Temperature; Carbamazepine; Epilepsy, Reflex; Female; Lamotrigine; Male; Metoprolol; Mice; Mice, Inbred DBA; Motor Activity; Phenobarbital; Propanolamines; Propranolol; Stereoisomerism; Triazines; Valproic Acid | 2002 |
P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cerebral Cortex; Drug Resistance, Multiple; Epilepsy; Extracellular Space; Felbamate; Female; Lamotrigine; Microdialysis; Phenobarbital; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar; Triazines; Up-Regulation; Verapamil | 2002 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Clinical pharmacology of topiramate versus lamotrigine versus phenobarbital: comparison of efficacy and side effects using odds ratios.
Topics: Anticonvulsants; Costs and Cost Analysis; Dose-Response Relationship, Drug; Epilepsy; Fructose; Humans; Lamotrigine; Odds Ratio; Phenobarbital; Topiramate; Triazines | 2003 |
Antiepileptic drugs inhibit cell growth in the human breast cancer cell line MCF7.
Topics: Anticonvulsants; Breast Neoplasms; Cell Division; Cell Line, Tumor; Drug Screening Assays, Antitumor; Estrogens; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Protein Binding; Receptors, Estrogen; Triazines; Valproic Acid | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Middle Aged; Phenobarbital; Phenytoin; Platelet Aggregation; Psychotropic Drugs; Thrombocytopenia; Triazines; Valproic Acid | 2004 |
Determination of levetiracetam in human plasma with minimal sample pretreatment.
Topics: Anticonvulsants; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Epilepsy; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Piracetam; Primidone; Triazines | 2005 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Triazines | 2005 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines | 2006 |
Psychological factors and use of antiepileptic drugs: pilot work using an objective measure of adherence.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Anxiety; Culture; Depression; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Internal-External Control; Lamotrigine; Male; Middle Aged; Patient Compliance; Phenobarbital; Sick Role; Surveys and Questionnaires; Triazines | 2007 |
Translocation-positive acute myeloid leukemia associated with valproic acid therapy.
Topics: Acute Disease; Anticonvulsants; Cell Differentiation; Cell Division; Child, Preschool; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 8; Clone Cells; Cocarcinogenesis; Drug Therapy, Combination; Epilepsy, Absence; Female; Humans; Isoxazoles; Lamotrigine; Leukemia, Myeloid; Levetiracetam; Neoplastic Stem Cells; Oncogene Proteins, Fusion; Phenobarbital; Piracetam; Translocation, Genetic; Triazines; Valproic Acid; Zonisamide | 2008 |
Effects of lamotrigine alone and in combination with MK-801, phenobarbital, or phenytoin on cell death in the neonatal rat brain.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Cerebral Cortex; Corpus Striatum; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Female; Lamotrigine; Male; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Sex Factors; Thalamus; Triazines | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Aseptic meningitis associated with lamotrigine: report of two cases.
Topics: Acquired Immunodeficiency Syndrome; Adult; Anticonvulsants; Blood; Blood Chemical Analysis; Cerebrospinal Fluid; Diagnosis, Differential; Female; Fever; Humans; Lamotrigine; Male; Meningitis, Aseptic; Meningitis, Bacterial; Meningitis, Viral; Phenobarbital; Triazines; Valproic Acid | 2007 |
Antiepileptic drugs and brain maturation: fetal exposure to lamotrigine generates cortical malformations in rats.
Topics: Animals; Anticonvulsants; Brain; Cell Count; Cell Movement; Dose-Response Relationship, Drug; Female; Fructose; Hippocampus; Immunohistochemistry; Lamotrigine; Levetiracetam; Litter Size; Malformations of Cortical Development; Neurons; Phenobarbital; Piracetam; Pregnancy; Rats; Rats, Wistar; Teratogens; Topiramate; Triazines; Weight Gain | 2008 |
Phenobarbital withdrawal seizures may occur over several weeks before remitting: human data and hypothetical mechanism.
Topics: Anticonvulsants; Data Collection; Female; Humans; Lamotrigine; Levetiracetam; Middle Aged; Phenobarbital; Piracetam; Seizures; Substance Withdrawal Syndrome; Time Factors; Triazines | 2009 |
[Anticonvulsant hypersensitivity syndrome and lamotrigine-associated anticonvulsant hypersensitivity syndrome].
Topics: Adult; Aged; Anticonvulsants; Bipolar Disorder; Drug Eruptions; Drug Hypersensitivity; Eosinophilia; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Fever; Humans; Lamotrigine; Male; Phenobarbital; Syndrome; Triazines | 2009 |
Hyperhomocysteinemia in epileptic patients on new antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Enzyme Induction; Epilepsy; Female; Folic Acid; Fructose; Genotype; Humans; Hyperhomocysteinemia; Lamotrigine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxcarbazepine; Phenobarbital; Polymorphism, Genetic; Topiramate; Triazines; Vitamin B 12 | 2010 |
Studies on induction of lamotrigine metabolism in transgenic UGT1 mice.
Topics: Animals; Anticonvulsants; Chromatography, High Pressure Liquid; Enzyme Induction; Female; GABA Modulators; Gas Chromatography-Mass Spectrometry; Glucuronosyltransferase; Hepatocytes; Humans; Kinetics; Lamotrigine; Male; Metabolic Clearance Rate; Mice; Mice, Transgenic; Microsomes, Liver; Peroxisome Proliferator-Activated Receptors; Peroxisome Proliferators; Phenobarbital; Pregnenolone Carbonitrile; Pyrimidines; Triazines | 2009 |
The effect of antiepileptic drugs on mitochondrial activity: a pilot study.
Topics: Adenosine Triphosphate; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electron Transport; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Epilepsy; Humans; Lamotrigine; Leukocytes; Mitochondria; Oxidation-Reduction; Phenobarbital; Phosphorylation; Pilot Projects; Signal Transduction; Time Factors; Triazines | 2010 |
Therapeutic strategies to avoid long-term adverse outcomes of neonatal antiepileptic drug exposure.
Topics: Animals; Animals, Newborn; Anticonvulsants; Corpus Striatum; Female; Humans; Lamotrigine; Mental Processes; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Receptors, GABA; Reflex; Synaptic Transmission; Triazines | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Fructose; Humans; Lamotrigine; Phenobarbital; Secondary Prevention; Status Epilepticus; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Weight Gain | 2010 |
Phenobarbital/Lamotrigine coadministration-induced blood dyscrasia in a patient with epilepsy.
Topics: Adult; Anticonvulsants; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Leukopenia; Phenobarbital; Thrombocytopenia; Triazines | 2010 |
Suicidal risk and suicide attempts in people treated with antiepileptic drugs for epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Comorbidity; Depressive Disorder; Electroencephalography; Epilepsy; Female; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Prohibitins; Risk Factors; Suicidal Ideation; Suicide; Suicide, Attempted; Triazines; Young Adult | 2011 |
Valproate treatment after liver transplant in a patient with Lennox-Gastaut syndrome.
Topics: Anticonvulsants; Chemical and Drug Induced Liver Injury; Electroencephalography; Female; Fructose; Humans; Immunosuppressive Agents; Intellectual Disability; Lamotrigine; Lennox Gastaut Syndrome; Liver Function Tests; Liver Transplantation; Phenobarbital; Seizures; Spasms, Infantile; Topiramate; Triazines; Valproic Acid; Young Adult | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Solubility prediction of drugs in mixed solvents using partial solubility parameters.
Topics: Clonazepam; Computer Simulation; Diazepam; Ethanol; Ibuprofen; Kinetics; Lamotrigine; Models, Molecular; Numerical Analysis, Computer-Assisted; Pharmaceutical Preparations; Phenobarbital; Propylene Glycol; Solubility; Solvents; Technology, Pharmaceutical; Temperature; Triazines; Water | 2011 |
Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Registries; Triazines; Valproic Acid | 2011 |
Development and validation of a reference measurement procedure for certification of phenytoin, phenobarbital, lamotrigine, and topiramate in human serum using isotope-dilution liquid chromatography/tandem mass spectrometry.
Topics: Anticonvulsants; Chromatography, Reverse-Phase; Fructose; Humans; Indicator Dilution Techniques; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Reference Standards; Sensitivity and Specificity; Solid Phase Extraction; Tandem Mass Spectrometry; Topiramate; Triazines | 2011 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
Effect of pregabalin add-on treatment on seizure control, quality of life, and anxiety in patients with brain tumour-related epilepsy: a pilot study.
Topics: Adult; Aged; Anticonvulsants; Anxiety; Benzodiazepines; Brain Neoplasms; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Fructose; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Pilot Projects; Piracetam; Pregabalin; Quality of Life; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plas
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Humans; Lamotrigine; Limit of Detection; Linear Models; Phenobarbital; Phenytoin; Reproducibility of Results; Triazines | 2013 |
Seizure control and treatment changes in pregnancy: observations from the EURAP epilepsy pregnancy registry.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Lamotrigine; Phenobarbital; Pregnancy; Pregnancy Complications; Registries; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2013 |
Antiepileptic efficacy of lamotrigine in phenobarbital-resistant and -responsive epileptic rats: a pilot study.
Topics: Animals; Anticonvulsants; Electric Stimulation; Electroencephalography; Epilepsy; Female; Lamotrigine; Phenobarbital; Pilot Projects; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Time Factors; Triazines | 2014 |
Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine.
Topics: Anticonvulsants; Carbamazepine; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dibenzazepines; Drug Monitoring; Epoxy Compounds; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Quality Control; Reproducibility of Results; Triazines | 2014 |
Nonlinear mixed effects modelling approach in investigating phenobarbital pharmacokinetic interactions in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Phenobarbital; Topiramate; Triazines; Valproic Acid | 2015 |
Poor neonatal adaptation following in-utero exposure to quetiapine and lamotrigine.
Topics: Adult; Antipsychotic Agents; Bipolar Disorder; Female; Humans; Hypothyroidism; Infant, Newborn; Infant, Newborn, Diseases; Lamotrigine; Maternal-Fetal Exchange; Phenobarbital; Pregnancy; Pregnancy Complications; Quetiapine Fumarate; Substance Withdrawal Syndrome; Triazines | 2015 |
Simultaneous extraction and quantification of lamotrigine, phenobarbital, and phenytoin in human plasma and urine samples using solidified floating organic drop microextraction and high-performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Lamotrigine; Limit of Detection; Liquid Phase Microextraction; Organic Chemicals; Osmolar Concentration; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Microextraction; Solvents; Temperature; Triazines | 2015 |
Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Pharmacovigilance; Phenobarbital; Spain; Stevens-Johnson Syndrome; Triazines; Valproic Acid; Young Adult | 2015 |
LIS1-associated classic lissencephaly: A retrospective, multicenter survey of the epileptogenic phenotype and response to antiepileptic drugs.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Adolescent; Adult; Anticonvulsants; Brain; Child; Child, Preschool; Classical Lissencephalies and Subcortical Band Heterotopias; Drug Resistant Epilepsy; Electroencephalography; Female; Humans; Infant; Lamotrigine; Male; Microtubule-Associated Proteins; Phenobarbital; Phenotype; Retrospective Studies; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin; Young Adult | 2016 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide | 2016 |
A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf-Hirschhorn syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clobazam; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Quality of Life; Seizures; Topiramate; Wolf-Hirschhorn Syndrome; Young Adult | 2018 |
Isobolographic additivity among lacosamide, lamotrigine and phenobarbital in a mouse tonic-clonic seizure model.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Epilepsy; Lacosamide; Lamotrigine; Male; Mice; Phenobarbital; Seizures | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
Adverse Cutaneous Drug Reactions Associated with Old- and New- Generation Antiepileptic Drugs Using the Japanese Pharmacovigilance Database.
Topics: Anticonvulsants; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Exanthema; Female; Humans; Japan; Lamotrigine; Male; Pharmacovigilance; Phenobarbital; Retrospective Studies; Stevens-Johnson Syndrome; Zonisamide | 2019 |
A 16q22.2-q23.1 deletion identified in a male infant with West syndrome.
Topics: Anticonvulsants; Chromosomes, Human, Pair 16; Epilepsy; Humans; Infant; Intellectual Disability; Lamotrigine; Male; Phenobarbital; Seizures; Sequence Deletion; Spasms, Infantile; Valproic Acid | 2019 |
Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.
Topics: Animals; Animals, Outbred Strains; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Cornea; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistant Epilepsy; Electroshock; Kindling, Neurologic; Lamotrigine; Levetiracetam; Locomotion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Open Field Test; Phenobarbital; Seizures; Treatment Outcome; Valproic Acid | 2020 |
Risk factors of paradoxical reactions to anti-seizure medication in genetic generalized epilepsy.
Topics: Adult; Anticonvulsants; Epilepsy, Generalized; Humans; Lamotrigine; Levetiracetam; Myoclonic Epilepsy, Juvenile; Phenobarbital; Retrospective Studies; Risk Factors; Seizures; Valproic Acid; Zonisamide | 2021 |
pH-induced homogeneous liquid-liquid microextraction method based on new switchable deep eutectic solvent for the extraction of three antiepileptic drugs from breast milk.
Topics: Anticonvulsants; Epilepsy; Female; Humans; Hydrogen-Ion Concentration; Lamotrigine; Liquid Phase Microextraction; Milk, Human; Phenobarbital; Phenytoin; Solvents | 2021 |
Effects of antiepileptic drugs polytherapy on pregnancy outcomes in women with epilepsy: An observation study in northwest China.
Topics: Anticonvulsants; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Male; Phenobarbital; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Registries; Topiramate; Valproic Acid | 2022 |