phenobarbital and lacosamide

phenobarbital has been researched along with lacosamide in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.57)18.2507
2000's4 (14.29)29.6817
2010's16 (57.14)24.3611
2020's7 (25.00)2.80

Authors

AuthorsStudies
Choi, D; Kohn, H; Stables, JP1
Kohn, H; LeTiran, A; Stables, JP1
Kohn, H; Morieux, P; Stables, JP1
Cotten, SW; Eyers, C; Gaskell, SJ; Kohn, H; Liu, R; Morieux, P; Park, KD; Reamtong, O; Salomé, C; Stables, JP1
DeMarco, E; Kohn, H; Morieux, P; Park, KD; Salomé, C; Salomé-Grosjean, E; Stables, JP; Swendiman, R1
Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP1
Kohn, H; Morieux, P; Park, KD; Salomé, C; Stables, JP1
De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Valade, A1
De Ryck, M; Kaminski, R; King, AM; Kohn, H; Salomé, C; Salomé-Grosjean, E; Stables, JP; Valade, A1
De Ryck, M; Kaminski, R; King, AM; Kohn, H; Stables, JP; Valade, A1
Chodkowski, A; Dawidowski, M; Herold, F; Kleps, J; Szulczyk, P; Wilczek, M1
Baruah, PK; De Ryck, M; Dinsmore, J; Kaminski, R; King, AM; Kohn, H; Provins, L; Salomé, C1
Dustrude, ET; Khanna, R; Kohn, H; Lee, H; Park, KD; Wilson, SM; Yang, XF1
Chońska, J; Dawidowski, M; Mika, W; Turło, J1
Cummins, TR; Dustrude, ET; Khanna, R; Kohn, H; Torregrosa, R; Yang, XF1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Errington, AC; Lees, G; Stöhr, T1
Bastin, ML; Cook, AM; Oyler, DR; Smetana, KS1
Andres-Mach, M; Chmielewski, J; Florek-Luszczki, M; Kondrat-Wrobel, MW; Luszczki, JJ; Patrzylas, P; Szpringer, M; Zagaja, M; Zaluska, K1
Kondrat-Wróbel, MW; Łuszczki, JJ1
Gaínza-Lein, M; Lamb, N; Loddenkemper, T; Sánchez Fernández, I1
Araki, Y; Fukushima, Y; Imai, K; Kagawa, Y; Takahashi, Y; Terada, K; Yamamoto, Y1
Amigoni, A; Bertozzi, V; Biscalchin, G; Bonardi, CM; Sartori, S; Tona, C1
Andres-Mach, M; Lemieszek, MK; Raszewski, G; Szala-Rycaj, J; Szewczyk, A; Zagaja, A; Zagaja, M1
Pavuluri, S; Schmidt, CM; Situ-Kcomt, M; Snehal, I; Taraschenko, O; Zhou, DJ1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T1
García-Peñas, JJ; González-Alguacil, E; Soto-Insuga, V1
Czabanka, M; Kieslich, M; Merker, M; Purwien, L; Ronellenfitsch, MW; Rosenow, F; Schubert-Bast, S; Strzelczyk, A; Willems, LM1

Reviews

6 review(s) available for phenobarbital and lacosamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antiepileptic dosing for critically ill adult patients receiving renal replacement therapy.
    Journal of critical care, 2016, Volume: 36

    Topics: Acetamides; Acute Kidney Injury; Amines; Anticonvulsants; Carbamates; Critical Illness; Cyclohexanecarboxylic Acids; Dibenzazepines; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lacosamide; Lamotrigine; Levetiracetam; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Renal Dialysis; Renal Replacement Therapy; Seizures; Topiramate; Triazines; Valproic Acid; Zonisamide

2016
Meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus.
    Neurology, 2019, 05-14, Volume: 92, Issue:20

    Topics: Anticonvulsants; Benzodiazepines; Cost-Benefit Analysis; Decision Support Techniques; Humans; Lacosamide; Levetiracetam; Phenobarbital; Phenytoin; Status Epilepticus; Treatment Failure; Valproic Acid

2019
Movement disorders associated with antiseizure medications: A systematic review.
    Epilepsy & behavior : E&B, 2022, Volume: 131, Issue:Pt A

    Topics: Anticonvulsants; Humans; Lacosamide; Movement Disorders; Phenobarbital; Valproic Acid

2022
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide

2022
[Paediatric status epilepticus].
    Revista de neurologia, 2022, 10-16, Volume: 75, Issue:8

    Topics: Adult; Anesthetics; Anticonvulsants; Benzodiazepines; Child; Epilepsy; Humans; Ketamine; Lacosamide; Levetiracetam; Lidocaine; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Topiramate; Valproic Acid

2022

Other Studies

22 other study(ies) available for phenobarbital and lacosamide

ArticleYear
Synthesis and anticonvulsant activities of N-Benzyl-2-acetamidopropionamide derivatives.
    Journal of medicinal chemistry, 1996, Apr-26, Volume: 39, Issue:9

    Topics: Acetamides; Animals; Anticonvulsants; Benzylamines; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism

1996
Design and evaluation of affinity labels of functionalized amino acid anticonvulsants.
    Journal of medicinal chemistry, 2002, Oct-10, Volume: 45, Issue:21

    Topics: Affinity Labels; Amino Acids; Animals; Anticonvulsants; Electroshock; Isothiocyanates; Mice; Radioligand Assay; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship

2002
Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives.
    Bioorganic & medicinal chemistry, 2008, Oct-01, Volume: 16, Issue:19

    Topics: Acetamides; Animals; Anticonvulsants; Binding Sites; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship

2008
Lacosamide isothiocyanate-based agents: novel agents to target and identify lacosamide receptors.
    Journal of medicinal chemistry, 2009, Nov-12, Volume: 52, Issue:21

    Topics: Acetamides; Animals; Anticonvulsants; Brain; In Vitro Techniques; Intercellular Signaling Peptides and Proteins; Isothiocyanates; Lacosamide; Male; Mice; Mice, Inbred ICR; Nerve Tissue Proteins; Proteome; Seizures; Serine; Stereoisomerism; Structure-Activity Relationship

2009
Synthesis and anticonvulsant activities of (R)-N-(4'-substituted)benzyl 2-acetamido-3-methoxypropionamides.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Acetamides; Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroshock; Hippocampus; Kindling, Neurologic; Male; Mice; Molecular Structure; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Serine; Structure-Activity Relationship

2010
Merging the structural motifs of functionalized amino acids and alpha-aminoamides: compounds with significant anticonvulsant activities.
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Acetamides; Alanine; Amides; Amino Acids; Animals; Anticonvulsants; Benzylamines; Drug Evaluation, Preclinical; Lacosamide; Mice; Pain; Rats; Seizures; Structure-Activity Relationship; Treatment Outcome

2010
The structure-activity relationship of the 3-oxy site in the anticonvulsant (R)-N-benzyl 2-acetamido-3-methoxypropionamide.
    Journal of medicinal chemistry, 2010, Aug-12, Volume: 53, Issue:15

    Topics: Acetamides; Animals; Anticonvulsants; Electroshock; Hydrophobic and Hydrophilic Interactions; Lacosamide; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship

2010
Primary amino acid derivatives: compounds with anticonvulsant and neuropathic pain protection activities.
    Journal of medicinal chemistry, 2011, Jul-14, Volume: 54, Issue:13

    Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Convulsants; Electroshock; Formaldehyde; Male; Mice; Neuralgia; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship

2011
Primary amino acid derivatives: substitution of the 4'-N'-benzylamide site in (R)-N'-benzyl 2-amino-3-methylbutanamide, (R)-N'-benzyl 2-amino-3,3-dimethylbutanamide, and (R)-N'-benzyl 2-amino-3-methoxypropionamide provides potent anticonvulsants with pain
    Journal of medicinal chemistry, 2011, Oct-13, Volume: 54, Issue:19

    Topics: Amino Acids; Analgesics; Animals; Anticonvulsants; Butyrates; Male; Mice; Neuralgia; Pain Measurement; Propionates; Rats; Rats, Sprague-Dawley; Seizures; Stereoisomerism; Structure-Activity Relationship

2011
Defining the structural parameters that confer anticonvulsant activity by the site-by-site modification of (R)-N'-benzyl 2-amino-3-methylbutanamide.
    Journal of medicinal chemistry, 2011, Oct-13, Volume: 54, Issue:19

    Topics: Aminobutyrates; Animals; Anticonvulsants; Male; Mice; Rats; Rats, Sprague-Dawley; Seizures; Solubility; Stereoisomerism; Structure-Activity Relationship

2011
Synthesis and anticonvulsant activity of novel 2,6-diketopiperazine derivatives. Part 1: perhydropyrrole[1,2-a]pyrazines.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:10

    Topics: Animals; Anticonvulsants; Diketopiperazines; Electroshock; Epilepsy; Humans; Male; Mice; Models, Molecular; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Sodium Channel Blockers; Sodium Channels

2011
Synthesis, anticonvulsant activity, and neuropathic pain-attenuating activity of N-benzyl 2-amino-2-(hetero)aromatic acetamides.
    Bioorganic & medicinal chemistry, 2012, Jun-01, Volume: 20, Issue:11

    Topics: Acetamides; Amino Acids; Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Male; Mice; Mice, Inbred Strains; Molecular Structure; Neuralgia; Seizures; Structure-Activity Relationship

2012
(Biphenyl-4-yl)methylammonium chlorides: potent anticonvulsants that modulate Na+ currents.
    Journal of medicinal chemistry, 2013, Jul-25, Volume: 56, Issue:14

    Topics: Ammonium Compounds; Animals; Anticonvulsants; Biphenyl Compounds; Male; Methylamines; Mice; Rats; Rats, Sprague-Dawley; Sodium Channels

2013
Novel fluorinated pyrrolo[1,2-a]pyrazine-2,6-dione derivatives: synthesis and anticonvulsant evaluation in animal models of epilepsy.
    Bioorganic & medicinal chemistry, 2014, Oct-01, Volume: 22, Issue:19

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Epilepsy; Halogenation; Hydrocarbons, Fluorinated; Male; Mice; Molecular Structure; Pentylenetetrazole; Pilocarpine; Pyrazines; Pyrroles; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship

2014
Chimeric derivatives of functionalized amino acids and α-aminoamides: compounds with anticonvulsant activity in seizure models and inhibitory actions on central, peripheral, and cardiac isoforms of voltage-gated sodium channels.
    Bioorganic & medicinal chemistry, 2015, Jul-01, Volume: 23, Issue:13

    Topics: Acetamides; Administration, Oral; Amides; Amino Acids; Animals; Anticonvulsants; Cerebral Cortex; Electroshock; HEK293 Cells; Humans; Injections, Intraperitoneal; Male; Mice; Neurons; Patch-Clamp Techniques; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels

2015
Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetamides; Animals; Anticonvulsants; Carbamazepine; Convulsants; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Female; In Vitro Techniques; Lacosamide; Male; Membrane Potentials; Patch-Clamp Techniques; Phenobarbital; Picrotoxin; Potassium Channel Blockers; Prohibitins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Visual Cortex

2006
Effects of arachidonyl-2'-chloroethylamide (ACEA) on the protective action of various antiepileptic drugs in the 6-Hz corneal stimulation model in mice.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Acetamides; Animals; Anticonvulsants; Arachidonic Acids; Avoidance Learning; Benzodiazepines; Clobazam; Cornea; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy, Complex Partial; Lacosamide; Levetiracetam; Male; Mice; Muscle Strength; Nipecotic Acids; Phenobarbital; Phenylmethylsulfonyl Fluoride; Piracetam; Psychomotor Performance; Receptor, Cannabinoid, CB1; Tiagabine; Valproic Acid

2017
Isobolographic additivity among lacosamide, lamotrigine and phenobarbital in a mouse tonic-clonic seizure model.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2018, Volume: 27, Issue:7

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Epilepsy; Lacosamide; Lamotrigine; Male; Mice; Phenobarbital; Seizures

2018
Therapeutic Monitoring of Lacosamide in Japanese Patients With Epilepsy: Clinical Response, Tolerability, and Optimal Therapeutic Range.
    Therapeutic drug monitoring, 2020, Volume: 42, Issue:5

    Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Lacosamide; Male; Phenobarbital; Phenytoin; Sodium Channel Blockers

2020
Efficacy of lacosamide in neonatal-onset super-refractory status epilepticus: a case report.
    Epileptic disorders : international epilepsy journal with videotape, 2021, Aug-01, Volume: 23, Issue:4

    Topics: Anticonvulsants; Humans; Infant, Newborn; Lacosamide; Phenobarbital; Seizures; Status Epilepticus

2021
Influence of Umbelliferone on the Anticonvulsant and Neuroprotective Activity of Selected Antiepileptic Drugs: An In Vivo and In Vitro Study.
    International journal of molecular sciences, 2022, Mar-23, Volume: 23, Issue:7

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Lacosamide; Mice; Phenobarbital; Seizures; Umbelliferones

2022
Trends and Differences in Status Epilepticus Treatment of Children and Adults Over 10 Years: A Comparative Study of Medical Records (2012-2021) from a University Hospital in Germany.
    CNS drugs, 2023, Volume: 37, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Child; Female; Hospitals, University; Humans; Lacosamide; Levetiracetam; Male; Medical Records; Midazolam; Middle Aged; Phenobarbital; Phenytoin; Propofol; Status Epilepticus; Valproic Acid

2023