phenobarbital and iproniazid

phenobarbital has been researched along with iproniazid in 29 studies

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199020 (68.97)18.7374
1990's2 (6.90)18.2507
2000's2 (6.90)29.6817
2010's5 (17.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Valla, D1
Timbrell, JA1
Gillette, JR; Mitchell, JR; Snodgrass, WR1
Horigan, E; King, CT; Wilk, AL1
Wilson, WS1
Bilodeau, F1
Dhasmana, KM; Fokker, WA; Spilker, BA1
Nefedova, ZV; Rudzit, EA; Terekhina, AI1
Calderoni, FJ; Mitoma, C; Neubauer, SE; Tagg, JS; Tanabe, M; Yasuda, D1
Burba, JV1
Buchel, L; Liblau, L; Murawsky, M; Prioux-Guyonneau, M1
Aston, R; Roberts, VL1
Gray, WD; Rauh, CE1
Barros, AR; Comendador, MA; Sierra, LM1
Bandou, R; Goromaru, T; Kiwada, H; Maeda, H; Matsuki, Y1
GIARMAN, NJ; SCHANBERG, SM1
FELDMAN, RS; LEWIS, E1
SCHENKER, S; WARREN, KS1
LIBERSON, WT1
MOORE, KE1
HEINONEN, J1
BENIGNO, P; PALAZZOADRIANO, M1

Reviews

2 review(s) available for phenobarbital and iproniazid

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The role of metabolism in the hepatotoxicity of isoniazid and iproniazid.
    Drug metabolism reviews, 1979, Volume: 10, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cobalt; Humans; Hydrazines; Iproniazid; Isoniazid; Phenobarbital

1979

Other Studies

27 other study(ies) available for phenobarbital and iproniazid

ArticleYear
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
[Hepatic metabolism of foreign substances. Enzymatic hydroxylation system of hepatic microsomes and of cytochrome P-450].
    Medecine & chirurgie digestives, 1978, Volume: 7, Issue:3

    Topics: Anticoagulants; Benzopyrenes; Biotransformation; Cytochrome P-450 Enzyme System; Epoxy Compounds; Ethanol; Humans; Hydroxylation; Iproniazid; Isoniazid; Liver; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Pharmaceutical Preparations; Phenobarbital

1978
The role of biotransformation in chemical-induced liver injury.
    Environmental health perspectives, 1976, Volume: 15

    Topics: Acetaminophen; Animals; Biotransformation; Bromobenzenes; Chemical and Drug Induced Liver Injury; Cricetinae; Furosemide; Glutathione; Guinea Pigs; Humans; In Vitro Techniques; Iproniazid; Isoniazid; Liver Diseases; Methylcholanthrene; Mice; Phenobarbital; Rats

1976
Fetal outcome from prolonged versus acute drug administration in the pregnant rat.
    Advances in experimental medicine and biology, 1972, Volume: 27

    Topics: Abnormalities, Drug-Induced; Aminopropionitrile; Animals; Cleft Palate; Collagen; Demyelinating Diseases; Drug Synergism; Female; Fetus; Gestational Age; Iproniazid; Lathyrism; Maternal-Fetal Exchange; Monoamine Oxidase Inhibitors; Pargyline; Phenobarbital; Piperazines; Pregnancy; Rats

1972
The effects of phenobarbitone, leptazol, dexamphetamine, iproniazid, imipramine, LSD, chlorpromazine, reserpine and hydroxyzine on the in vivo levels of adenine nucleotides and phosphocreatine in the rat brain.
    British journal of pharmacology, 1969, Volume: 36, Issue:3

    Topics: Adenine Nucleotides; Adenosine Triphosphatases; Animals; Brain Chemistry; Chlorpromazine; Dextroamphetamine; Hydroxyzine; Imipramine; Iproniazid; Lysergic Acid Diethylamide; Male; Pentylenetetrazole; Phenobarbital; Phosphocreatine; Rats; Reserpine

1969
Effects of stimulants of the central nervous system on the pyridoxal phosphate content of the rat brain.
    Journal of neurochemistry, 1965, Volume: 12, Issue:7

    Topics: Amphetamine; Animals; Brain; Central Nervous System Stimulants; Injections, Intraperitoneal; Iproniazid; Kidney; Liver; Muscles; Phenobarbital; Pyridoxal Phosphate; Rats; Seizures; Semicarbazides

1965
Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cordotomy; Diazoxide; Electric Stimulation; Ergotamine; Guanethidine; Hydrochlorothiazide; Iproniazid; Male; Mecamylamine; Methyldopa; Pargyline; Phenobarbital; Rats; Reserpine; Sympathetic Nervous System; Thiocyanates; Trimethaphan

1972
[Participation of liver microsome enzyme systems in the metabolism of penicillin].
    Farmakologiia i toksikologiia, 1972, Volume: 35, Issue:4

    Topics: Animals; Biotransformation; Hexobarbital; Iproniazid; Microsomes, Liver; Muscles; Penicillins; Phenobarbital; Rabbits; Rats

1972
Effects of various chemical agents on drug metabolism and cholesterol biosynthesis.
    Biochemical pharmacology, 1968, Volume: 17, Issue:7

    Topics: Acetanilides; Acetates; Aminopyrine; Animals; Anticholesteremic Agents; Benzopyrenes; Carbon Isotopes; Chloramphenicol; Cholesterol; Depression, Chemical; Drug Synergism; Ethers; Ethylamines; Hexobarbital; Insecticides; Iproniazid; Liver; Male; Mevalonic Acid; Microsomes; Nitrophenols; Phenobarbital; Proadifen; Rabbits; Rats; Sleep; Time Factors

1968
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
    Canadian journal of biochemistry, 1968, Volume: 46, Issue:4

    Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione

1968
[Influence of pyschotropic substances on variations of total plasma free fatty acids in constrained rats].
    Archives des sciences physiologiques, 1969, Volume: 23, Issue:3

    Topics: Animals; Chlorpromazine; Depression, Chemical; Dextromoramide; Fatty Acids, Nonesterified; Female; Hypothermia; Iproniazid; Peptic Ulcer; Phenobarbital; Rats; Stress, Physiological

1969
The effect of drugs on vibration tolerance.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:2

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Hydroxyzine; In Vitro Techniques; Iproniazid; Lung; Mephenesin; Meprobamate; Mice; Morphine; Mortality; Pentobarbital; Phenobarbital; Phenoxybenzamine; Reserpine; Serotonin; Stress, Physiological; Vibration

1965
The anticonvulsant action of inhibitors of carbonic anhydrase: relation to endogenous amines in brain.
    The Journal of pharmacology and experimental therapeutics, 1967, Volume: 155, Issue:1

    Topics: Animals; Brain Chemistry; Carbonic Anhydrase Inhibitors; Dopamine; Iproniazid; Male; Methazolamide; Mice; Norepinephrine; Phenobarbital; Phenytoin; Reserpine; Serotonin

1967
Acrolein genotoxicity in Drosophila melanogaster. III. Effects of metabolism modification.
    Mutation research, 1994, Volume: 321, Issue:3

    Topics: Acrolein; Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Drosophila melanogaster; Female; Glutathione; Imidazoles; Iproniazid; Male; Maleates; Mutagenicity Tests; Mutation; Phenobarbital

1994
Effects of ascorbic acid on iproniazid-induced hepatitis in phenobarbital-treated rats.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:8

    Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Hydrazines; Iproniazid; Kinetics; Liver; Liver Function Tests; Male; Phenobarbital; Rats; Rats, Wistar

1994
Drug-induced alterations of the sub-cellular distribution of 5-hydroxytryptamine (serotonin) in rat's brain.
    Biochemical pharmacology, 1962, Volume: 9

    Topics: Animals; Brain; Chlorpromazine; Dihydroxyphenylalanine; Hydrazines; Hypnotics and Sedatives; Imipramine; Iproniazid; Lysergic Acid Diethylamide; Phenobarbital; Rats; Reserpine; Serotonin

1962
Response differences of psychotropic drugs in rats during chronic anxiety states.
    Journal of neuropsychiatry, 1962, Volume: 3(Suppl 1)

    Topics: Animals; Anxiety; Chlordiazepoxide; Chlorpromazine; Conditioning, Classical; Conditioning, Psychological; Convulsive Therapy; Dextroamphetamine; Electricity; Electroconvulsive Therapy; Iproniazid; Meprobamate; Phenobarbital; Psychotropic Drugs; Rats; Reserpine

1962
DRUGS RELATED TO THE EXACERBATION OR AMELIORATION OF HEPATIC COMA AND THEIR EFFECTS ON AMMONIA TOXICITY.
    Clinical science, 1963, Volume: 25

    Topics: Acetazolamide; Ammonia; Ammonium Chloride; Arginine; Chlorothiazide; Cortisone; Formaldehyde; Glutamates; Hepatic Encephalopathy; Hydrogen-Ion Concentration; Iproniazid; Mice; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Research; Toxicology; Tryptophan

1963
INTERACTION OF MOTIVATIONAL AND DRUG EFFECTS IN ANIMAL BEHAVIOR RESEARCH.
    The Journal of nervous and mental disease, 1964, Volume: 138

    Topics: Animals; Avoidance Learning; Behavior, Animal; Chlordiazepoxide; Chlorpromazine; Electricity; Guinea Pigs; Humans; Iproniazid; Meprobamate; Motivation; Phenobarbital; Psychopharmacology; Rats; Research; Reserpine

1964
THE ROLE OF ENDOGENOUS NOREPINEPHRINE IN THE TOXICITY OF D-AMPHETAMINE IN AGGREGATED MICE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 144

    Topics: Atropine; Brain Chemistry; Bretylium Compounds; Chlorpromazine; Dextroamphetamine; Hydrazines; Iproniazid; Isoproterenol; Metabolism; Metaraminol; Mice; Myocardium; Norepinephrine; Pharmacology; Phenobarbital; Phenoxybenzamine; Research; Reserpine; Scopolamine; Toxicology

1964
THE EFFECT OF DRUGS ON THE DURATION OF TOXIC SYMPTOMS CAUSED BY SUBLETHAL DOSES OF LOCAL ANESTHETICS. AN EXPERIMENTAL STUDY ON MICE.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Anesthetics; Anesthetics, Local; Barbiturates; Bemegride; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Ethionine; Iproniazid; Isoniazid; Lidocaine; Mepivacaine; Meprobamate; Mice; Nikethamide; Pentobarbital; Pharmacology; Phenobarbital; Research; Toxicology

1964
[ON POTENTIATION OF THE EFFECTS OF BARBITURATES BY CYSTEAMINE (BETA-MERCAPTOETHYLAMINE)].
    Archives internationales de pharmacodynamie et de therapie, 1964, Sep-01, Volume: 151

    Topics: Barbiturates; Cell Respiration; Central Nervous System; Cysteamine; Iproniazid; Liver; Mitochondria; Monoamine Oxidase; Nervous System; Pharmacology; Phenobarbital; Rabbits; Rats; Research; Respiration; Serotonin; Thiopental

1964