phenobarbital has been researched along with indomethacin in 70 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 36 (51.43) | 18.7374 |
1990's | 8 (11.43) | 18.2507 |
2000's | 17 (24.29) | 29.6817 |
2010's | 9 (12.86) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A | 1 |
Strassburg, CP; Tukey, RH | 1 |
Duffy, EM; Jorgensen, WL | 1 |
Topliss, JG; Yoshida, F | 1 |
Caron, G; Ermondi, G | 1 |
Carrupt, PA; Martel, S; Ottaviani, G | 2 |
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Sen, S; Sinha, N | 1 |
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Dittgen, M; Kala, H; Zessin, G | 1 |
Bell, MA; Brooks, PM; Buchanan, WW; Mason, DI | 1 |
Fujihira, E; Sandeman, VA; Whitehouse, MW | 1 |
Dittgen, M; Kala, H; Schmollack, W | 2 |
Assandri, A; Perazzi, A | 1 |
Klaassen, CD | 1 |
Autret, E; Laugier, J; Nasr, C; Saliba, E; Suc, AL | 1 |
Awad, JA; Badr, KF; Burk, RF; Kato, T; Morrow, JD; Roberts, LJ; Takahashi, K | 1 |
Cheymol, G; Lebot, M; Poirier, JM | 1 |
Morales, WJ | 1 |
Ment, LR | 1 |
Fedchenko, LG; Neĭmark, EZ; Stegniĭ, AS | 1 |
Volpe, JJ | 1 |
Duncan, CC; Ehrenkranz, RA; Ment, LR | 1 |
Hirose, M; Inoue, T; Ito, N; Masuda, A; Tsuda, H | 1 |
Perlman, JM; Volpe, JJ | 1 |
DeAngelo, AB; Guion, C; Pereira, MA; Savage, RE | 1 |
Kauffman, RE | 1 |
Aranda, JV; Beharry, K; Clozel, M | 1 |
Bisschop, A; Uijtewaal, B; van Rooijen, LA | 1 |
Kusenbach, G; Reinhardt, D | 1 |
Forsberg, JG; Hillbertz-Nilsson, K | 1 |
Aramphongphan, A; Kobayashi, S; Kurata, N; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H | 1 |
Selye, H; Szabo, S; Taché, Y | 1 |
Cockrill, BL; Platt, DS | 1 |
Behrman, HR; Greep, RO; Orczyk, GP | 1 |
Chernish, SM; Crabtree, R; Gruber, CM; Helleberg, L; Ridolfo, AS; Rodda, BE; Rubin, A; Warrick, P; Wolen, RL | 1 |
Koch, Y; Lindner, HR; Tsafriri, A | 1 |
Brown, JK; De Cato, L; Malone, MH | 1 |
Klinger, W; Reinicke, C | 1 |
Becker, B; Klutho, L; Koloms, BA; Krupin, T; Webb, G | 1 |
Duwe, K; Kuhnz, W; Nau, H; Wittfoht, W | 1 |
Kuhnz, W; Luck, W; Nau, H; Wegener, S | 1 |
Andreis, PG; Armato, U; Romano, F | 1 |
Hobara, N; Watanabe, A | 1 |
Zenk, KE | 1 |
Dahlgren, N; Siesjö, BK | 1 |
Budíková, M; Hajdúch, M; Jezdinská, V; Weigl, E; Zpĕvácková, L | 1 |
Kuwabara, Y; Watanabe, A | 1 |
Idaewor, PE; Isah, AO; Omogbai, EK; Ozolua, RI | 1 |
Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E | 1 |
Ekekezie, II; Mundy, DC; Okah, FA | 1 |
Chen, HW; Li, CC; Lii, CK; Liu, KL; Yang, JJ | 1 |
Emilova, Z; Garnizov, T; Kalaĭdzhieva, M; Slŭncheva, B; Vakrilova, L | 1 |
Levene, M | 1 |
Iijima, M | 1 |
McCrea, HJ; Ment, LR | 1 |
Cha, DS; Jeon, H; Park, HJ | 1 |
12 review(s) available for phenobarbital and indomethacin
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antenatal therapy to minimize neonatal intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; Infant, Newborn; Phenobarbital; Pregnancy; Prenatal Care; Risk Factors; Vitamin K | 1991 |
Intraventricular hemorrhage of the preterm neonate: prevention studies.
Topics: Animals; Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Ethamsylate; Humans; Incidence; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital; Risk Factors; Vitamin E | 1988 |
Intraventricular hemorrhage in the premature infant--current concepts. Part II.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Combined Modality Therapy; Echoencephalography; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Prognosis; Vitamin E | 1989 |
Intraventricular hemorrhage of the preterm neonate: prevention studies.
Topics: Animals; Benzenesulfonates; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital; Vitamin E | 1988 |
Prevention of neonatal intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Cerebrovascular Circulation; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Vitamin E | 1987 |
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Pancuronium; Phenobarbital; Risk; Vitamin E | 1986 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline | 1981 |
Minimising neonatal brain injury: how research in the past five years has changed my clinical practice.
Topics: Animals; Birth Injuries; Brain Diseases; Dexamethasone; Disease Models, Animal; Ethamsylate; Humans; Hypocapnia; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Lung Diseases; Phenobarbital | 2007 |
[Judicial judgment for severe adverse drug reaction (ADR)].
Topics: Clinical Competence; Humans; Indomethacin; Liability, Legal; Malpractice; Phenobarbital; Referral and Consultation; Stevens-Johnson Syndrome | 2007 |
The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Coagulants; Cyclooxygenase Inhibitors; Factor VIIa; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital | 2008 |
4 trial(s) available for phenobarbital and indomethacin
Article | Year |
---|---|
Intraventricular hemorrhage of the preterm neonate: prevention studies.
Topics: Animals; Benzenesulfonates; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital; Vitamin E | 1988 |
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Pancuronium; Phenobarbital; Risk; Vitamin E | 1986 |
A profile of the physiological disposition and gastro-intestinal effects of fenoprofen in man.
Topics: Administration, Oral; Adult; Age Factors; Animals; Anti-Inflammatory Agents; Aspirin; Biotransformation; Child; Clinical Trials as Topic; Drug Interactions; Gastrointestinal Diseases; Humans; Indomethacin; Injections, Intravenous; Phenobarbital; Phenyl Ethers; Phenylpropionates; Placebos; Protein Binding; Rats | 1974 |
[Prevention of brain hemorrhage in infants with low and extremely low birth weight and infants treated with surfactants. Late observation].
Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Drug Therapy, Combination; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Phenobarbital; Pulmonary Surfactants; Risk Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial | 2006 |
56 other study(ies) available for phenobarbital and indomethacin
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.
Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors | 1980 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water | 2006 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
[Drug liberation from imbedded forms with a polyacrylate base].
Topics: Acrylates; Chemistry, Pharmaceutical; Citrates; Creatinine; Delayed-Action Preparations; Diffusion; Indomethacin; Medazepam; Niacinamide; Phenacetin; Phenobarbital | 1977 |
Interactions of anti-rheumatic drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Furosemide; Humans; Indomethacin; Phenobarbital | 1977 |
Pathobiodynamics: reduction in hepatic and intestinal ligandin (glutathione-S-transferase) levels in rats with severe acute and chronic inflammation.
Topics: Animals; Arthritis; Arthritis, Experimental; Copper; Cytosol; Glutathione Transferase; Indomethacin; Intestine, Small; Liver; Male; Phenobarbital; Phenylbutazone; Rats; Sulfhydryl Compounds; Sulfobromophthalein | 1979 |
[Production of drug-containing pearl polymerisates on the basis of ternary polyacrylates].
Topics: Acrylates; Dosage Forms; Drug Compounding; Indomethacin; Meprobamate; Methacrylates; Phenobarbital; Polymers | 1977 |
Competition between diftalone and other drugs for the binding site(s) on human serum albumin.
Topics: Acetaminophen; Aspirin; Binding Sites; Dexamethasone; Drug Interactions; Humans; Indomethacin; Phenobarbital; Phenylbutazone; Phthalazines; Protein Binding; Pyridazines; Serum Albumin; Temperature; Tolbutamide; Warfarin | 1976 |
Studies on the mechanism of spironolactone protection against indomethacin toxicity.
Topics: Animals; Bile; Depression, Chemical; Enzyme Induction; In Vitro Techniques; Indomethacin; Male; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Time Factors | 1976 |
[The preparation of drug-containing bead polymerizates on polyacrylate bases].
Topics: Acrylates; Chemistry, Pharmaceutical; Croton Oil; Indomethacin; Medazepam; Meprobamate; Nitrazepam; Phenobarbital; Polymers | 1976 |
Perinatal pharmacology and cerebral blood flow.
Topics: Arteries; Blood Flow Velocity; Caffeine; Carbon Dioxide; Cerebrovascular Circulation; Drug Combinations; Fatty Alcohols; Humans; Indomethacin; Infant, Newborn; Partial Pressure; Phenobarbital; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1992 |
Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation.
Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Indomethacin; Isoniazid; Lipid Peroxides; Male; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Thioacetamide | 1992 |
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Least-Squares Analysis; Mefenamic Acid; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Sensitivity and Specificity; Valproic Acid | 1992 |
[Treatment of vertebrogenic lumbosacral radiculitis and lumbar ischialgia by transcutaneous-cavitary electrophoresis of drugs].
Topics: Administration, Rectal; Adult; Aminopyrine; Back Pain; Colon, Sigmoid; Dexamethasone; Diphenhydramine; Dipyrone; Drug Therapy, Combination; Female; Humans; Indomethacin; Iontophoresis; Lumbosacral Region; Male; Middle Aged; Phenobarbital; Prednisolone; Procaine; Radiculopathy | 1989 |
Effects of simultaneous treatment with various chemicals on BHA-induced development of rat forestomach hyperplasia--complete inhibition by diethylmaleate in a 5-week feeding study.
Topics: Aminocaproic Acid; Animals; Body Weight; Butylated Hydroxyanisole; Dexamethasone; Diet; Diterpenes; Drug Interactions; Eating; Indomethacin; Liver; Male; Maleates; Organ Size; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Retinyl Esters; Stomach; Vitamin A | 1987 |
Studies on the mechanism of action of chloroform stimulation of rat hepatic ornithine decarboxylase (ODC).
Topics: Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chloroform; Cytosol; Female; Indomethacin; Injections, Intravenous; Liver; Male; Maleates; Ornithine Decarboxylase; Phenobarbital; Propranolol; Rats; Rats, Inbred F344; Reserpine; Stimulation, Chemical | 1987 |
Indomethacin metabolism in liver microsomes during postnatal development in the rat.
Topics: Aging; Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Enzyme Induction; In Vitro Techniques; Indomethacin; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1986 |
Inhibition by indomethacin and 5,8,11,14-eicosatetraynoic acid of the induction of rat hepatic ornithine decarboxylase by the tumor promoters phenobarbital and 12-O-tetradecanoylphorbol-13-acetate in vivo.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Drug Interactions; Enzyme Induction; Fatty Acids, Unsaturated; Female; Indomethacin; Liver; Ornithine Decarboxylase; Phenobarbital; Rats; Tetradecanoylphorbol Acetate | 1987 |
[Peculiarities of drug therapy in childhood].
Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone; Drug Therapy; Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Receptors, Drug; Theophylline; Tissue Distribution | 1986 |
Estrogen effects on sister chromatid exchanges in mouse uterine cervical and kidney cells.
Topics: Animals; Benzoflavones; Cells, Cultured; Cervix Uteri; Diethylstilbestrol; Dose-Response Relationship, Drug; Estradiol; Female; Indomethacin; Kidney; Mice; Mice, Inbred Strains; Phenobarbital; Pregnancy; Sister Chromatid Exchange | 1985 |
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator.
Topics: Animals; Antipyrine; Half-Life; Indomethacin; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione | 1985 |
Interruption of pregnancy by various steroids.
Topics: Abortion, Induced; Anabolic Agents; Animals; Cholesterol; Dehydroepiandrosterone; Dexamethasone; Digitoxin; Estradiol; Ethylestrenol; Female; Indomethacin; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnenolone; Progesterone; Rats; Spironolactone; Steroids; Triamcinolone | 1971 |
Biochemical changes in rat liver in response to treatment with drugs and other agents. I. Effects of anticonvulsant, anti-inflammatory, hypocholesterolaemic and adrenergic beta-blocking agents.
Topics: Acetanilides; Aminopyrine; Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Anticonvulsants; Barbiturates; Body Weight; Butyrates; Cytochromes; Cytoplasm; Electron Transport; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Microsomes; Organ Size; Oxidoreductases; Phenobarbital; Phenylbutazone; Phenytoin; Phosphogluconate Dehydrogenase; Propranolol; Proteins; Rats; Sympatholytics | 1969 |
Effect of synthetic gonadotrophin-releasing hormone (Gn-RH) on ovulation blockade by aspirin and indomethacin.
Topics: Adrenal Glands; Animals; Aspirin; Depression, Chemical; Drug Interactions; Female; Gonadotropins, Equine; Hypothalamus; Indomethacin; Luteinizing Hormone; Organ Size; Ovulation; Ovum; Phenobarbital; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Prostaglandins; Radioimmunoassay; Rats; Time Factors; Uterus | 1972 |
Ovulation rate and serum LH levels in rats treated with indomethacin or prostaglandin E2.
Topics: Animals; Depression, Chemical; Estrus; Female; Indomethacin; Injections, Intraperitoneal; Injections, Subcutaneous; Luteinizing Hormone; Ovulation; Ovum; Phenobarbital; Pregnancy; Prostaglandins; Radioimmunoassay; Rats; Stimulation, Chemical; Time Factors | 1973 |
Effects of benzoquinolizine homologues on proliferative and exudative inflammation.
Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Body Weight; Carrageenan; Catecholamines; Chlorpromazine; Dose-Response Relationship, Drug; Edema; Exudates and Transudates; Food Deprivation; Hydrocortisone; Indomethacin; Inflammation; Male; Organ Size; Phenobarbital; Phenylbutazone; Quinolizines; Rats; Reserpine; Tetrabenazine; Water Deprivation | 1974 |
Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Benzyl Compounds; Enzyme Induction; Flufenamic Acid; Hexobarbital; In Vitro Techniques; Indazoles; Indomethacin; Liver; Male; Mefenamic Acid; Methylamines; Methyltransferases; Microsomes, Liver; Organ Size; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Salicylamides; Salicylates; Sleep; Sodium Salicylate | 1971 |
Increased intraocular pressure and hyperthermia following administration of substance P into rabbit third ventricle.
Topics: Acetazolamide; Animals; Aqueous Humor; Body Temperature; Dose-Response Relationship, Drug; Fever; Indomethacin; Injections, Intraventricular; Intraocular Pressure; Phenobarbital; Phentolamine; Rabbits; Substance P | 1982 |
Microscale ultrafiltration technique for determining free drug in 50-microL serum samples.
Topics: Animals; Chloramphenicol; Diazepam; Furosemide; Humans; Indomethacin; Infant; Infant, Newborn; Microchemistry; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ultrafiltration; Valproic Acid | 1984 |
Serum protein binding of diazepam, desmethyldiazepam, furosemide, indomethacin, warfarin, and phenobarbital in human fetus, mother, and newborn infant.
Topics: Blood Proteins; Diazepam; Fatty Acids, Nonesterified; Female; Fetal Blood; Furosemide; Humans; Indomethacin; Infant, Newborn; Maternal-Fetal Exchange; Nordazepam; Phenobarbital; Pregnancy; Protein Binding; Warfarin | 1983 |
The tumor promoters TPA, phenobarbital, and nafenopin and the prostaglandins of A, E, and F series overcome the G1/S block imposed by extracellular calcium deprivation on neonatal rat hepatocytes.
Topics: Animals; Calcium; Carcinogens; Cell Cycle; Cells, Cultured; DNA Replication; Female; Hormones; Imidazoles; Indomethacin; Liver; Male; Nafenopin; Phenobarbital; Prostaglandins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1984 |
Altered pharmacodynamics of 1-(2-tetrahydrofuryl)-5-fluorouracil by pretreatment of rats with phenobarbital, indomethacin, diclofenac sodium and carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Diclofenac; Female; Fluorouracil; Indomethacin; Microsomes, Liver; Phenobarbital; Phenylacetates; Rats; Tegafur; Time Factors | 1980 |
Effects of indomethacin on cerebral blood flow and oxygen consumption in barbiturate-anesthetized Normocapnic and hypercapnic rats.
Topics: Anesthetics; Animals; Brain; Cerebrovascular Circulation; Hypercapnia; Indomethacin; Nitrous Oxide; Oxygen; Oxygen Consumption; Phenobarbital; Rats; Rats, Inbred Strains | 1981 |
Some biochemical characteristics of the early phase of immunomodulation.
Topics: Adjuvants, Immunologic; Animals; Female; Geotrichum; Indomethacin; Luminescent Measurements; Mice; Phagocytosis; Phenobarbital; Polysaccharides; Propionibacterium acnes; Serum Albumin, Bovine | 1994 |
Hyperammonemia induced in rats by inhalation anesthesia with ether.
Topics: Ammonia; Anesthesia, Inhalation; Animals; Carbon Tetrachloride; Ether; Indomethacin; Liver; Male; Phenobarbital; Rats; Rats, Wistar | 1994 |
Some studies on the rodenticidal action of indomethacin.
Topics: Administration, Oral; Animals; Bile Ducts; Body Weight; Cholestyramine Resin; Diazepam; Drug Interactions; Female; Indomethacin; Lethal Dose 50; Male; Peptic Ulcer Perforation; Phenobarbital; Rats; Rats, Wistar; Rodent Control; Rodenticides; Stomach Ulcer; Toxicity Tests | 1999 |
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2 | 1999 |
Combining phenobarbital and indomethacin to improve early neonatal outcomes in the extremely low birth weight infant.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Therapy, Combination; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight; Intracranial Hemorrhages; Logistic Models; Phenobarbital; Pregnancy; Pregnancy Outcome; Retrospective Studies | 2005 |
n-6 and n-3 polyunsaturated fatty acids down-regulate cytochrome P-450 2B1 gene expression induced by phenobarbital in primary rat hepatocytes.
Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Arachidonic Acid; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2B1; Dinoprostone; Docosahexaenoic Acids; Down-Regulation; Enzyme Inhibitors; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Gene Expression; Hepatocytes; Indomethacin; L-Lactate Dehydrogenase; Male; Phenobarbital; Rats; Rats, Sprague-Dawley | 2006 |
Antinociceptive and hypnotic properties of Celastrus orbiculatus.
Topics: Acetic Acid; Animals; Celastrus; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Hypnotics and Sedatives; Indomethacin; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Phenobarbital; Plant Extracts; Plants, Medicinal; Reaction Time; Sleep; Time Factors; Tramadol | 2011 |