phenobarbital and indomethacin

phenobarbital has been researched along with indomethacin in 70 studies

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199036 (51.43)18.7374
1990's8 (11.43)18.2507
2000's17 (24.29)29.6817
2010's9 (12.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Lüllmann, H; Timmermans, PB; Weikert, GM; Ziegler, A1
Strassburg, CP; Tukey, RH1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Caron, G; Ermondi, G1
Carrupt, PA; Martel, S; Ottaviani, G2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dittgen, M; Kala, H; Zessin, G1
Bell, MA; Brooks, PM; Buchanan, WW; Mason, DI1
Fujihira, E; Sandeman, VA; Whitehouse, MW1
Dittgen, M; Kala, H; Schmollack, W2
Assandri, A; Perazzi, A1
Klaassen, CD1
Autret, E; Laugier, J; Nasr, C; Saliba, E; Suc, AL1
Awad, JA; Badr, KF; Burk, RF; Kato, T; Morrow, JD; Roberts, LJ; Takahashi, K1
Cheymol, G; Lebot, M; Poirier, JM1
Morales, WJ1
Ment, LR1
Fedchenko, LG; Neĭmark, EZ; Stegniĭ, AS1
Volpe, JJ1
Duncan, CC; Ehrenkranz, RA; Ment, LR1
Hirose, M; Inoue, T; Ito, N; Masuda, A; Tsuda, H1
Perlman, JM; Volpe, JJ1
DeAngelo, AB; Guion, C; Pereira, MA; Savage, RE1
Kauffman, RE1
Aranda, JV; Beharry, K; Clozel, M1
Bisschop, A; Uijtewaal, B; van Rooijen, LA1
Kusenbach, G; Reinhardt, D1
Forsberg, JG; Hillbertz-Nilsson, K1
Aramphongphan, A; Kobayashi, S; Kurata, N; Kuroiwa, Y; Oguchi, K; Tanaka, E; Yasuhara, H1
Selye, H; Szabo, S; Taché, Y1
Cockrill, BL; Platt, DS1
Behrman, HR; Greep, RO; Orczyk, GP1
Chernish, SM; Crabtree, R; Gruber, CM; Helleberg, L; Ridolfo, AS; Rodda, BE; Rubin, A; Warrick, P; Wolen, RL1
Koch, Y; Lindner, HR; Tsafriri, A1
Brown, JK; De Cato, L; Malone, MH1
Klinger, W; Reinicke, C1
Becker, B; Klutho, L; Koloms, BA; Krupin, T; Webb, G1
Duwe, K; Kuhnz, W; Nau, H; Wittfoht, W1
Kuhnz, W; Luck, W; Nau, H; Wegener, S1
Andreis, PG; Armato, U; Romano, F1
Hobara, N; Watanabe, A1
Zenk, KE1
Dahlgren, N; Siesjö, BK1
Budíková, M; Hajdúch, M; Jezdinská, V; Weigl, E; Zpĕvácková, L1
Kuwabara, Y; Watanabe, A1
Idaewor, PE; Isah, AO; Omogbai, EK; Ozolua, RI1
Chiang, N; Clària, J; Gaya, J; Pueyo, G; Romano, M; Serhan, CN; Titos, E1
Ekekezie, II; Mundy, DC; Okah, FA1
Chen, HW; Li, CC; Lii, CK; Liu, KL; Yang, JJ1
Emilova, Z; Garnizov, T; Kalaĭdzhieva, M; Slŭncheva, B; Vakrilova, L1
Levene, M1
Iijima, M1
McCrea, HJ; Ment, LR1
Cha, DS; Jeon, H; Park, HJ1

Reviews

12 review(s) available for phenobarbital and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antenatal therapy to minimize neonatal intraventricular hemorrhage.
    Clinical obstetrics and gynecology, 1991, Volume: 34, Issue:2

    Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; Infant, Newborn; Phenobarbital; Pregnancy; Prenatal Care; Risk Factors; Vitamin K

1991
Intraventricular hemorrhage of the preterm neonate: prevention studies.
    Mead Johnson Symposium on Perinatal and Developmental Medicine, 1988, Issue:33

    Topics: Animals; Cerebral Hemorrhage; Cerebral Ventricles; Clinical Trials as Topic; Ethamsylate; Humans; Incidence; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital; Risk Factors; Vitamin E

1988
Intraventricular hemorrhage in the premature infant--current concepts. Part II.
    Annals of neurology, 1989, Volume: 25, Issue:2

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Combined Modality Therapy; Echoencephalography; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Prognosis; Vitamin E

1989
Intraventricular hemorrhage of the preterm neonate: prevention studies.
    Seminars in perinatology, 1988, Volume: 12, Issue:4

    Topics: Animals; Benzenesulfonates; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital; Vitamin E

1988
Prevention of neonatal intraventricular hemorrhage.
    Clinical neuropharmacology, 1987, Volume: 10, Issue:2

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Cerebrovascular Circulation; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital; Vitamin E

1987
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
    The Journal of pediatrics, 1986, Volume: 108, Issue:2

    Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Pancuronium; Phenobarbital; Risk; Vitamin E

1986
An overview of perinatal clinical pharmacology.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline

1981
Minimising neonatal brain injury: how research in the past five years has changed my clinical practice.
    Archives of disease in childhood, 2007, Volume: 92, Issue:3

    Topics: Animals; Birth Injuries; Brain Diseases; Dexamethasone; Disease Models, Animal; Ethamsylate; Humans; Hypocapnia; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Lung Diseases; Phenobarbital

2007
[Judicial judgment for severe adverse drug reaction (ADR)].
    Arerugi = [Allergy], 2007, Volume: 56, Issue:11

    Topics: Clinical Competence; Humans; Indomethacin; Liability, Legal; Malpractice; Phenobarbital; Referral and Consultation; Stevens-Johnson Syndrome

2007
The diagnosis, management, and postnatal prevention of intraventricular hemorrhage in the preterm neonate.
    Clinics in perinatology, 2008, Volume: 35, Issue:4

    Topics: Cerebral Hemorrhage; Cerebral Ventricles; Coagulants; Cyclooxygenase Inhibitors; Factor VIIa; Humans; Ibuprofen; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital

2008

Trials

4 trial(s) available for phenobarbital and indomethacin

ArticleYear
Intraventricular hemorrhage of the preterm neonate: prevention studies.
    Seminars in perinatology, 1988, Volume: 12, Issue:4

    Topics: Animals; Benzenesulfonates; Brain; Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Phenobarbital; Vitamin E

1988
Therapeutic interventions to prevent intracerebral hemorrhage in preterm infants.
    The Journal of pediatrics, 1986, Volume: 108, Issue:2

    Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Clinical Trials as Topic; Ethamsylate; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Pancuronium; Phenobarbital; Risk; Vitamin E

1986
A profile of the physiological disposition and gastro-intestinal effects of fenoprofen in man.
    Current medical research and opinion, 1974, Volume: 2, Issue:9

    Topics: Administration, Oral; Adult; Age Factors; Animals; Anti-Inflammatory Agents; Aspirin; Biotransformation; Child; Clinical Trials as Topic; Drug Interactions; Gastrointestinal Diseases; Humans; Indomethacin; Injections, Intravenous; Phenobarbital; Phenyl Ethers; Phenylpropionates; Placebos; Protein Binding; Rats

1974
[Prevention of brain hemorrhage in infants with low and extremely low birth weight and infants treated with surfactants. Late observation].
    Akusherstvo i ginekologiia, 2006, Volume: 45, Issue:3

    Topics: Cerebral Hemorrhage; Cerebrovascular Circulation; Drug Therapy, Combination; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Infant, Very Low Birth Weight; Phenobarbital; Pulmonary Surfactants; Risk Factors; Treatment Outcome; Ultrasonography, Doppler, Transcranial

2006

Other Studies

56 other study(ies) available for phenobarbital and indomethacin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Accumulation of drugs by guinea pig isolated atria. Quantitative correlations.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:5

    Topics: Animals; Chemistry, Pharmaceutical; Electric Stimulation; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Myocardium; Pharmaceutical Preparations; Protein Binding; Serum Albumin; Solubility; Time Factors

1980
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
    Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13

    Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water

2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
[Drug liberation from imbedded forms with a polyacrylate base].
    Die Pharmazie, 1977, Volume: 32, Issue:12

    Topics: Acrylates; Chemistry, Pharmaceutical; Citrates; Creatinine; Delayed-Action Preparations; Diffusion; Indomethacin; Medazepam; Niacinamide; Phenacetin; Phenobarbital

1977
Interactions of anti-rheumatic drugs.
    Agents and actions. Supplements, 1977, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Interactions; Furosemide; Humans; Indomethacin; Phenobarbital

1977
Pathobiodynamics: reduction in hepatic and intestinal ligandin (glutathione-S-transferase) levels in rats with severe acute and chronic inflammation.
    Biochemical medicine, 1979, Volume: 22, Issue:2

    Topics: Animals; Arthritis; Arthritis, Experimental; Copper; Cytosol; Glutathione Transferase; Indomethacin; Intestine, Small; Liver; Male; Phenobarbital; Phenylbutazone; Rats; Sulfhydryl Compounds; Sulfobromophthalein

1979
[Production of drug-containing pearl polymerisates on the basis of ternary polyacrylates].
    Die Pharmazie, 1977, Volume: 32, Issue:3

    Topics: Acrylates; Dosage Forms; Drug Compounding; Indomethacin; Meprobamate; Methacrylates; Phenobarbital; Polymers

1977
Competition between diftalone and other drugs for the binding site(s) on human serum albumin.
    Medical biology, 1976, Volume: 54, Issue:3

    Topics: Acetaminophen; Aspirin; Binding Sites; Dexamethasone; Drug Interactions; Humans; Indomethacin; Phenobarbital; Phenylbutazone; Phthalazines; Protein Binding; Pyridazines; Serum Albumin; Temperature; Tolbutamide; Warfarin

1976
Studies on the mechanism of spironolactone protection against indomethacin toxicity.
    Toxicology and applied pharmacology, 1976, Volume: 38, Issue:1

    Topics: Animals; Bile; Depression, Chemical; Enzyme Induction; In Vitro Techniques; Indomethacin; Male; Phenobarbital; Pregnenolone Carbonitrile; Rats; Spironolactone; Time Factors

1976
[The preparation of drug-containing bead polymerizates on polyacrylate bases].
    Die Pharmazie, 1976, Volume: 31, Issue:11

    Topics: Acrylates; Chemistry, Pharmaceutical; Croton Oil; Indomethacin; Medazepam; Meprobamate; Nitrazepam; Phenobarbital; Polymers

1976
Perinatal pharmacology and cerebral blood flow.
    Biology of the neonate, 1992, Volume: 62, Issue:4

    Topics: Arteries; Blood Flow Velocity; Caffeine; Carbon Dioxide; Cerebrovascular Circulation; Drug Combinations; Fatty Alcohols; Humans; Indomethacin; Infant, Newborn; Partial Pressure; Phenobarbital; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants

1992
Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation.
    The Journal of clinical investigation, 1992, Volume: 90, Issue:6

    Topics: Acetaminophen; Alanine Transaminase; Animals; Carbon Tetrachloride; Indomethacin; Isoniazid; Lipid Peroxides; Male; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Thioacetamide

1992
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
    Therapeutic drug monitoring, 1992, Volume: 14, Issue:4

    Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Least-Squares Analysis; Mefenamic Acid; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Sensitivity and Specificity; Valproic Acid

1992
[Treatment of vertebrogenic lumbosacral radiculitis and lumbar ischialgia by transcutaneous-cavitary electrophoresis of drugs].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1989, Volume: 89, Issue:12

    Topics: Administration, Rectal; Adult; Aminopyrine; Back Pain; Colon, Sigmoid; Dexamethasone; Diphenhydramine; Dipyrone; Drug Therapy, Combination; Female; Humans; Indomethacin; Iontophoresis; Lumbosacral Region; Male; Middle Aged; Phenobarbital; Prednisolone; Procaine; Radiculopathy

1989
Effects of simultaneous treatment with various chemicals on BHA-induced development of rat forestomach hyperplasia--complete inhibition by diethylmaleate in a 5-week feeding study.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Aminocaproic Acid; Animals; Body Weight; Butylated Hydroxyanisole; Dexamethasone; Diet; Diterpenes; Drug Interactions; Eating; Indomethacin; Liver; Male; Maleates; Organ Size; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Retinyl Esters; Stomach; Vitamin A

1987
Studies on the mechanism of action of chloroform stimulation of rat hepatic ornithine decarboxylase (ODC).
    Research communications in chemical pathology and pharmacology, 1987, Volume: 58, Issue:1

    Topics: Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chloroform; Cytosol; Female; Indomethacin; Injections, Intravenous; Liver; Male; Maleates; Ornithine Decarboxylase; Phenobarbital; Propranolol; Rats; Rats, Inbred F344; Reserpine; Stimulation, Chemical

1987
Indomethacin metabolism in liver microsomes during postnatal development in the rat.
    Biology of the neonate, 1986, Volume: 50, Issue:2

    Topics: Aging; Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Enzyme Induction; In Vitro Techniques; Indomethacin; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains

1986
Inhibition by indomethacin and 5,8,11,14-eicosatetraynoic acid of the induction of rat hepatic ornithine decarboxylase by the tumor promoters phenobarbital and 12-O-tetradecanoylphorbol-13-acetate in vivo.
    Carcinogenesis, 1987, Volume: 8, Issue:1

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Drug Interactions; Enzyme Induction; Fatty Acids, Unsaturated; Female; Indomethacin; Liver; Ornithine Decarboxylase; Phenobarbital; Rats; Tetradecanoylphorbol Acetate

1987
[Peculiarities of drug therapy in childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:11

    Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone; Drug Therapy; Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Receptors, Drug; Theophylline; Tissue Distribution

1986
Estrogen effects on sister chromatid exchanges in mouse uterine cervical and kidney cells.
    Journal of the National Cancer Institute, 1985, Volume: 75, Issue:3

    Topics: Animals; Benzoflavones; Cells, Cultured; Cervix Uteri; Diethylstilbestrol; Dose-Response Relationship, Drug; Estradiol; Female; Indomethacin; Kidney; Mice; Mice, Inbred Strains; Phenobarbital; Pregnancy; Sister Chromatid Exchange

1985
The effect of indomethacin on hepatic drug-oxidizing capacity in the rat: trimethadione and antipyrine metabolism as an indicator.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9

    Topics: Animals; Antipyrine; Half-Life; Indomethacin; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxazoles; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione

1985
Interruption of pregnancy by various steroids.
    Fertility and sterility, 1971, Volume: 22, Issue:11

    Topics: Abortion, Induced; Anabolic Agents; Animals; Cholesterol; Dehydroepiandrosterone; Dexamethasone; Digitoxin; Estradiol; Ethylestrenol; Female; Indomethacin; Oxandrolone; Phenobarbital; Prednisolone; Pregnancy; Pregnenolone; Progesterone; Rats; Spironolactone; Steroids; Triamcinolone

1971
Biochemical changes in rat liver in response to treatment with drugs and other agents. I. Effects of anticonvulsant, anti-inflammatory, hypocholesterolaemic and adrenergic beta-blocking agents.
    Biochemical pharmacology, 1969, Volume: 18, Issue:2

    Topics: Acetanilides; Aminopyrine; Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Anticonvulsants; Barbiturates; Body Weight; Butyrates; Cytochromes; Cytoplasm; Electron Transport; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Microsomes; Organ Size; Oxidoreductases; Phenobarbital; Phenylbutazone; Phenytoin; Phosphogluconate Dehydrogenase; Propranolol; Proteins; Rats; Sympatholytics

1969
Effect of synthetic gonadotrophin-releasing hormone (Gn-RH) on ovulation blockade by aspirin and indomethacin.
    Prostaglandins, 1972, Volume: 1, Issue:4

    Topics: Adrenal Glands; Animals; Aspirin; Depression, Chemical; Drug Interactions; Female; Gonadotropins, Equine; Hypothalamus; Indomethacin; Luteinizing Hormone; Organ Size; Ovulation; Ovum; Phenobarbital; Pituitary Gland; Pituitary Hormone-Releasing Hormones; Prostaglandins; Radioimmunoassay; Rats; Time Factors; Uterus

1972
Ovulation rate and serum LH levels in rats treated with indomethacin or prostaglandin E2.
    Prostaglandins, 1973, Volume: 3, Issue:4

    Topics: Animals; Depression, Chemical; Estrus; Female; Indomethacin; Injections, Intraperitoneal; Injections, Subcutaneous; Luteinizing Hormone; Ovulation; Ovum; Phenobarbital; Pregnancy; Prostaglandins; Radioimmunoassay; Rats; Stimulation, Chemical; Time Factors

1973
Effects of benzoquinolizine homologues on proliferative and exudative inflammation.
    European journal of pharmacology, 1974, Volume: 26, Issue:1

    Topics: Adrenal Glands; Animals; Anti-Inflammatory Agents; Body Weight; Carrageenan; Catecholamines; Chlorpromazine; Dose-Response Relationship, Drug; Edema; Exudates and Transudates; Food Deprivation; Hydrocortisone; Indomethacin; Inflammation; Male; Organ Size; Phenobarbital; Phenylbutazone; Quinolizines; Rats; Reserpine; Tetrabenazine; Water Deprivation

1974
Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver.
    Biochemical pharmacology, 1971, Volume: 20, Issue:7

    Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Benzyl Compounds; Enzyme Induction; Flufenamic Acid; Hexobarbital; In Vitro Techniques; Indazoles; Indomethacin; Liver; Male; Mefenamic Acid; Methylamines; Methyltransferases; Microsomes, Liver; Organ Size; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Salicylamides; Salicylates; Sleep; Sodium Salicylate

1971
Increased intraocular pressure and hyperthermia following administration of substance P into rabbit third ventricle.
    Experimental eye research, 1982, Volume: 34, Issue:3

    Topics: Acetazolamide; Animals; Aqueous Humor; Body Temperature; Dose-Response Relationship, Drug; Fever; Indomethacin; Injections, Intraventricular; Intraocular Pressure; Phenobarbital; Phentolamine; Rabbits; Substance P

1982
Microscale ultrafiltration technique for determining free drug in 50-microL serum samples.
    Clinical chemistry, 1984, Volume: 30, Issue:6

    Topics: Animals; Chloramphenicol; Diazepam; Furosemide; Humans; Indomethacin; Infant; Infant, Newborn; Microchemistry; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ultrafiltration; Valproic Acid

1984
Serum protein binding of diazepam, desmethyldiazepam, furosemide, indomethacin, warfarin, and phenobarbital in human fetus, mother, and newborn infant.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:3-4

    Topics: Blood Proteins; Diazepam; Fatty Acids, Nonesterified; Female; Fetal Blood; Furosemide; Humans; Indomethacin; Infant, Newborn; Maternal-Fetal Exchange; Nordazepam; Phenobarbital; Pregnancy; Protein Binding; Warfarin

1983
The tumor promoters TPA, phenobarbital, and nafenopin and the prostaglandins of A, E, and F series overcome the G1/S block imposed by extracellular calcium deprivation on neonatal rat hepatocytes.
    Prostaglandins, leukotrienes, and medicine, 1984, Volume: 13, Issue:3

    Topics: Animals; Calcium; Carcinogens; Cell Cycle; Cells, Cultured; DNA Replication; Female; Hormones; Imidazoles; Indomethacin; Liver; Male; Nafenopin; Phenobarbital; Prostaglandins; Rats; Rats, Inbred Strains; Tetradecanoylphorbol Acetate

1984
Altered pharmacodynamics of 1-(2-tetrahydrofuryl)-5-fluorouracil by pretreatment of rats with phenobarbital, indomethacin, diclofenac sodium and carbon tetrachloride.
    Pharmacology, 1980, Volume: 21, Issue:5

    Topics: Animals; Carbon Tetrachloride; Diclofenac; Female; Fluorouracil; Indomethacin; Microsomes, Liver; Phenobarbital; Phenylacetates; Rats; Tegafur; Time Factors

1980
Effects of indomethacin on cerebral blood flow and oxygen consumption in barbiturate-anesthetized Normocapnic and hypercapnic rats.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1981, Volume: 1, Issue:1

    Topics: Anesthetics; Animals; Brain; Cerebrovascular Circulation; Hypercapnia; Indomethacin; Nitrous Oxide; Oxygen; Oxygen Consumption; Phenobarbital; Rats; Rats, Inbred Strains

1981
Some biochemical characteristics of the early phase of immunomodulation.
    Acta Universitatis Palackianae Olomucensis Facultatis Medicae, 1994, Volume: 137

    Topics: Adjuvants, Immunologic; Animals; Female; Geotrichum; Indomethacin; Luminescent Measurements; Mice; Phagocytosis; Phenobarbital; Polysaccharides; Propionibacterium acnes; Serum Albumin, Bovine

1994
Hyperammonemia induced in rats by inhalation anesthesia with ether.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1994, Volume: 194, Issue:3

    Topics: Ammonia; Anesthesia, Inhalation; Animals; Carbon Tetrachloride; Ether; Indomethacin; Liver; Male; Phenobarbital; Rats; Rats, Wistar

1994
Some studies on the rodenticidal action of indomethacin.
    Drug and chemical toxicology, 1999, Volume: 22, Issue:4

    Topics: Administration, Oral; Animals; Bile Ducts; Body Weight; Cholestyramine Resin; Diazepam; Drug Interactions; Female; Indomethacin; Lethal Dose 50; Male; Peptic Ulcer Perforation; Phenobarbital; Rats; Rats, Wistar; Rodent Control; Rodenticides; Stomach Ulcer; Toxicity Tests

1999
Hepatocytes are a rich source of novel aspirin-triggered 15-epi-lipoxin A(4).
    The American journal of physiology, 1999, Volume: 277, Issue:5

    Topics: Animals; Aspirin; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Activation; Excitatory Amino Acid Antagonists; Gene Expression Regulation, Enzymologic; Hydroxyeicosatetraenoic Acids; Ibuprofen; Indomethacin; Isoenzymes; Lipoxins; Liver; Male; Membrane Proteins; Phenobarbital; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; RNA, Messenger; Sulfonamides; Thromboxane B2

1999
Combining phenobarbital and indomethacin to improve early neonatal outcomes in the extremely low birth weight infant.
    American journal of perinatology, 2005, Volume: 22, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Therapy, Combination; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infant, Very Low Birth Weight; Intracranial Hemorrhages; Logistic Models; Phenobarbital; Pregnancy; Pregnancy Outcome; Retrospective Studies

2005
n-6 and n-3 polyunsaturated fatty acids down-regulate cytochrome P-450 2B1 gene expression induced by phenobarbital in primary rat hepatocytes.
    The Journal of nutritional biochemistry, 2006, Volume: 17, Issue:10

    Topics: Adenylyl Cyclase Inhibitors; Alprostadil; Animals; Arachidonic Acid; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2B1; Dinoprostone; Docosahexaenoic Acids; Down-Regulation; Enzyme Inhibitors; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Gene Expression; Hepatocytes; Indomethacin; L-Lactate Dehydrogenase; Male; Phenobarbital; Rats; Rats, Sprague-Dawley

2006
Antinociceptive and hypnotic properties of Celastrus orbiculatus.
    Journal of ethnopharmacology, 2011, Oct-11, Volume: 137, Issue:3

    Topics: Acetic Acid; Animals; Celastrus; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Hypnotics and Sedatives; Indomethacin; Male; Mice; Mice, Inbred ICR; Naloxone; Narcotic Antagonists; Pain; Pain Measurement; Pain Threshold; Phenobarbital; Plant Extracts; Plants, Medicinal; Reaction Time; Sleep; Time Factors; Tramadol

2011