phenobarbital and hydroxyzine

phenobarbital has been researched along with hydroxyzine in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199019 (63.33)18.7374
1990's2 (6.67)18.2507
2000's3 (10.00)29.6817
2010's6 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Caron, G; Ermondi, G1
Abraham, MH; Acree, WE; Ibrahim, A1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Rossum, JM; Yih, TD1
Cavellat, JF; Lepoittevin, L; Merlin, G; Mylonas, J; Turcant, A1
Marcy, R; Quermonne, MA1
Wiśniewski, K1
Wilson, WS1
Clark, DB; Critchley, EM; Wikler, A1
Kaniike, K; Kurogochi, Y1
Arnold, K; Gerber, N1
Patterson, A; Walker, BE1
Rubinstein, E; Whitcomb, NJ1
Ban, TA; Jarrold, L; Sterlin, C1
Forsythe, WI; Redmond, A1
Molinengo, L; Ricci-Gamalero, S1
Beard, JD; Knott, DH1
Ibrahim, I; Sulman, FG; Weller, CP1
Elliott, RC; Quilliam, JP1
Aston, R; Roberts, VL1
Dordain, G; Goulon, M; Lévy-Alcover, MA; Nouailhat, F1
Carlson, RK; Little, TL; Tielke, VM1
Born, JD; Brichant, JF; Hans, P; Lamy, M; Pieron, F; Pieyns, P1

Reviews

1 review(s) available for phenobarbital and hydroxyzine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for phenobarbital and hydroxyzine

ArticleYear
Clinical effectiveness of commonly used oral bronchodilators in asthmatic children.
    Annals of allergy, 1973, Volume: 31, Issue:12

    Topics: Administration, Oral; Adolescent; Asthma; Bronchodilator Agents; Child; Child, Preschool; Clinical Trials as Topic; Ephedrine; Female; Humans; Hydroxyzine; Male; Phenobarbital; Placebos; Respiration; Theophylline

1973
The place of doxepin among the anxiolytic-sedative drugs.
    Current therapeutic research, clinical and experimental, 1972, Volume: 14, Issue:4

    Topics: Adult; Analysis of Variance; Antidepressive Agents; Chlordiazepoxide; Clinical Trials as Topic; Demography; Dibenzoxepins; Evaluation Studies as Topic; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Meprobamate; Middle Aged; Neurotic Disorders; Phenobarbital; Psychiatric Status Rating Scales

1972

Other Studies

27 other study(ies) available for phenobarbital and hydroxyzine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Peculiar pharmacokinetics of brallobarbital as a source of complications in Vesparax intoxication.
    Xenobiotica; the fate of foreign compounds in biological systems, 1976, Volume: 6, Issue:6

    Topics: Administration, Oral; Animals; Barbiturates; Drug Combinations; Half-Life; Hydroxyzine; Injections, Intravenous; Kinetics; Liver; Male; Perfusion; Phenobarbital; Rats; Secobarbital; Sleep

1976
[Responsibility of psychotropic drugs in road accidents].
    Presse medicale (Paris, France : 1983), 1991, Mar-09, Volume: 20, Issue:9

    Topics: Accidents, Traffic; Adolescent; Adult; Aged; Aged, 80 and over; Benzodiazepines; Ethanol; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Male; Middle Aged; Phenobarbital; Pyridines; Zolpidem

1991
An improved method for studying the psychogalvanic reaction in mice and its inhibition by psycholeptic drugs. Comparison with the effects of other pharmacological agents.
    Psychopharmacologia, 1974, Feb-06, Volume: 34, Issue:4

    Topics: Adrenergic alpha-Antagonists; Animals; Benactyzine; Chlordiazepoxide; Chlorpromazine; Diazepam; Female; Galvanic Skin Response; Haloperidol; Hydroxyzine; Hypnotics and Sedatives; Male; Meprobamate; Methaqualone; Methotrimeprazine; Mice; Muscle Relaxants, Central; Neuromuscular Nondepolarizing Agents; Nitrazepam; Parasympatholytics; Pentobarbital; Phenobarbital; Phenothiazines; Thioridazine; Tranquilizing Agents; Trifluperidol

1974
[The studies on "nonspecific transport effect" of insulin].
    Roczniki Akademii Medycznej im. Juliana Marchlewskiego w Bialymstoku. Suplement, 1968, Volume: 20

    Topics: Adenosine Triphosphatases; Animals; Biological Transport; Brain Chemistry; Cell Membrane Permeability; Chlorpromazine; Diabetes Mellitus, Experimental; Drug Synergism; Hydroxyzine; Insulin; Isoniazid; Phenobarbital; Rats; Reserpine

1968
The effects of phenobarbitone, leptazol, dexamphetamine, iproniazid, imipramine, LSD, chlorpromazine, reserpine and hydroxyzine on the in vivo levels of adenine nucleotides and phosphocreatine in the rat brain.
    British journal of pharmacology, 1969, Volume: 36, Issue:3

    Topics: Adenine Nucleotides; Adenosine Triphosphatases; Animals; Brain Chemistry; Chlorpromazine; Dextroamphetamine; Hydroxyzine; Imipramine; Iproniazid; Lysergic Acid Diethylamide; Male; Pentylenetetrazole; Phenobarbital; Phosphocreatine; Rats; Reserpine

1969
An adult form of acanthocytosis.
    Transactions of the American Neurological Association, 1967, Volume: 92

    Topics: Abetalipoproteinemia; Adult; Ataxia; Diazepam; Female; Haloperidol; Humans; Huntington Disease; Hydroxyzine; Male; Phenobarbital; Phenytoin; Trihexyphenidyl

1967
[Effect of psychotropic drugs on the K + -dependent phosphatase activity in guinea pig brain microsomes].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1972, Volume: 68, Issue:1

    Topics: Amitriptyline; Animals; Antidepressive Agents; Brain; Chlordiazepoxide; Chlorpromazine; Desipramine; Diazepam; Guinea Pigs; Histamine; Hydroxyzine; Imipramine; Meprobamate; Microsomes; Morphine; Nialamide; Phenelzine; Phenobarbital; Phenoxybenzamine; Phosphoric Monoester Hydrolases; Pilocarpine; Potassium; Procaine; Reserpine; Tranquilizing Agents

1972
The effect of diphenyl-piperazine compounds and other agents on diphenylhydantoin, zoxazolamine and hexobarbital metabolism.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 164, Issue:1

    Topics: Animals; Benzopyrenes; Cyclizine; DDT; Diphenhydramine; Endoplasmic Reticulum; Hexobarbital; Humans; Hydroxyzine; Liver; Male; Meclizine; Methylcholanthrene; Mice; Microscopy, Electron; Phenethylamines; Phenobarbital; Phenytoin; Piperazines; Trifluoperazine; Zoxazolamine

1968
Induction of cleft palate in mice by tranquilizers and barbiturates.
    Teratology, 1974, Volume: 10, Issue:2

    Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Cleft Palate; Diazepam; Female; Hydroxyzine; Maternal-Fetal Exchange; Mice; Mice, Inbred A; Mice, Inbred C3H; Pentobarbital; Phenobarbital; Pregnancy; Teratogens; Tranquilizing Agents

1974
Enuresis and spontaneous cure rate. Study of 1129 enuretis.
    Archives of disease in childhood, 1974, Volume: 49, Issue:4

    Topics: Adolescent; Adult; Age Factors; Aged; Atropine; Child; Child, Preschool; Diuretics; Enuresis; Epinephrine; Female; Follow-Up Studies; Humans; Hydroxyzine; Male; Phenobarbital; Psychotherapy; Sex Factors; Urination; Urine; Urography

1974
The "staircase maze" and the "simple staircase" in the analysis of the psychopharmacological action of CNS depressants.
    Pharmacology, 1970, Volume: 4, Issue:3

    Topics: Analgesics; Animals; Barbiturates; Behavior, Animal; Central Nervous System; Chlorpromazine; Hydroxyzine; Hypnotics and Sedatives; Meperidine; Methadone; Morphine; Paraldehyde; Pentobarbital; Phenobarbital; Rats; Reserpine; Tranquilizing Agents

1970
Diagnosis and therapy of acute withdrawal from alcohol.
    Current psychiatric therapies, 1970, Volume: 10

    Topics: Acute Disease; Adult; Alcoholism; Anti-Bacterial Agents; Anticonvulsants; Carbohydrate Metabolism; Chloral Hydrate; Deficiency Diseases; Electrolytes; Female; Humans; Hydroxyzine; Hypnotics and Sedatives; Hypoglycemia; Male; Paraldehyde; Phenobarbital; Phenothiazines; Psychoses, Alcoholic; Substance Withdrawal Syndrome; Water-Electrolyte Balance

1970
Analgesic profile of tranquillizers in multiple screening tests in mice.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1

    Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents

1968
Centrally-active drugs and the discharge rate of spontaneously occurring action potentials in the superior cervical trunk of the cat.
    British journal of pharmacology, 1968, Volume: 34, Issue:3

    Topics: Action Potentials; Animals; Cats; Ganglia, Autonomic; Hydroxyzine; Perphenazine; Phenobarbital

1968
The effect of drugs on vibration tolerance.
    Archives internationales de pharmacodynamie et de therapie, 1965, Volume: 155, Issue:2

    Topics: Animals; Chlordiazepoxide; Chlorpromazine; Dextroamphetamine; Hydroxyzine; In Vitro Techniques; Iproniazid; Lung; Mephenesin; Meprobamate; Mice; Morphine; Mortality; Pentobarbital; Phenobarbital; Phenoxybenzamine; Reserpine; Serotonin; Stress, Physiological; Vibration

1965
[Toxic coma with autonomic sideration, with a favorable outcome].
    Revue neurologique, 1967, Volume: 116, Issue:4

    Topics: Adult; Amobarbital; Body Temperature; Brain; Cardiovascular System; Chlorpromazine; Coma; Diazepam; Dysautonomia, Familial; Electroencephalography; Female; Humans; Hydroxyzine; Imipramine; Male; Meprobamate; Methotrimeprazine; Middle Aged; Neurologic Manifestations; Phenelzine; Phenobarbital; Poisoning; Respiratory System; Secobarbital; Thioridazine; Tranquilizing Agents

1967
Stability of methadone pain cocktails.
    American journal of hospital pharmacy, 1982, Volume: 39, Issue:4

    Topics: Amitriptyline; Drug Combinations; Drug Stability; Hydroxyzine; Methadone; Phenobarbital

1982
Elevated plasma alpha 1-acid glycoprotein levels: lack of connection to resistance to vecuronium blockade induced by anticonvulsant therapy.
    Journal of neurosurgical anesthesiology, 1997, Volume: 9, Issue:1

    Topics: Adult; Alprazolam; Anticonvulsants; Atropine; Biomarkers; Carbamazepine; Drug Interactions; Drug Resistance; Humans; Hydroxyzine; Hypnotics and Sedatives; Middle Aged; Neuromuscular Nondepolarizing Agents; Neurosurgery; Orosomucoid; Phenobarbital; Phenytoin; Vecuronium Bromide

1997