phenobarbital and hydrazine

phenobarbital has been researched along with hydrazine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199032 (86.49)18.7374
1990's4 (10.81)18.2507
2000's0 (0.00)29.6817
2010's1 (2.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glen, RC; Lowe, R; Mitchell, JB1
Danisman, A; Diehl, B; Habs, M; Schmähl, D1
Timbrell, JA1
Alleva, FR; Alleva, JJ; Lipien, MW1
Brand, LM; Harper, AE1
Niederland, TR1
Albano, E; Botti, B; Tomasi, A; Vannini, V1
Ishizawa, M; Noda, A; Noda, H; Ohno, K; Sendo, T1
Bufalari, A; Cavaliere, A; Vitali, R1
Lauterburg, BH; Mitchell, JR; Smith, CV; Todd, EL1
Goto, S; Hsu, KY; Noda, A; Noda, H; Ohno, K; Sendo, T1
Behrens, BC; Bryan, GT; Ichikawa, M; Wang, CY1
De la Torre, JC; Kawanaga, HM; Mullan, S1
Mansuy, D; Nastainczyk, W; Ullrich, V1
Prough, RA; Reed, DJ; Wittkop, JA2
Cates, NR1
Fairchild, MD; Sterman, MB1
Roberts, E; Simonsen, DG1
Aebi, H; Baggiolini, M; Dewald, B1
Azar, A; Shillito, FH; Thomas, AA1
Kolber-Postepska, B1
Baggiolini, M; Bickel, MH; Messiha, FS1
Timbrell, JA; Woodward, KN1
Hines, RN; Nelson, RE; Prough, RA; Sieg, MS; Wiebkin, P1
Bahri, AK; Chiang, CS; Timbrell, JA2
Asano, T; Nakajima, A; Shimada, O; Yasuda, H1
Albano, E; Clot, P; Comoglio, A; Iannone, A; Ingelman-Sundberg, M; Tomasi, A1
Bandou, R; Goromaru, T; Kiwada, H; Maeda, H; Matsuki, Y1
Jenner, AM; Timbrell, JA1
Horie, Y; Karbowski, M; Kurono, C; Nishizawa, Y; Soji, T; Wakabayashi, T1
GIARMAN, NJ; SCHANBERG, SM1
OHTSUKI, I; OZAWA, H1
MOORE, KE1
LEVI, R; MAYNERT, EW1
KANG, CH; MINARD, FN; MUSHAHWAR, IK1

Reviews

1 review(s) available for phenobarbital and hydrazine

ArticleYear
The role of metabolism in the hepatotoxicity of isoniazid and iproniazid.
    Drug metabolism reviews, 1979, Volume: 10, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cobalt; Humans; Hydrazines; Iproniazid; Isoniazid; Phenobarbital

1979

Other Studies

36 other study(ies) available for phenobarbital and hydrazine

ArticleYear
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Experimental investigations on the influence upon the chemical carcinogenesis. IIIrd communication: studies with 1,2-dimethylhydrazine.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, May-03, Volume: 86, Issue:1

    Topics: Animals; BCG Vaccine; Diet; Dimethylhydrazines; Ear Neoplasms; Female; Hydrazines; Immunosuppressive Agents; Intestinal Neoplasms; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Phenobarbital; Rats; Serum Albumin; Tretinoin

1976
Use of vaginal concretions of calcium carbonate to detect ovulation in hamsters.
    Laboratory animal science, 1976, Volume: 26, Issue:1

    Topics: Animals; Calcium Carbonate; Cricetinae; Estrus; Female; Gonadotropins, Pituitary; Hydrazines; Ovulation; Ovulation Detection; Ovum; Phenobarbital; Pregnancy; Pseudopregnancy; Vagina

1976
DL-alpha-Hydrazinoimidazolylpropionic acid: an irreversible inhibitor of hepatic histidine ammonia-lyase in vivo.
    Archives of biochemistry and biophysics, 1976, Volume: 177, Issue:1

    Topics: Ammonia-Lyases; Animals; Histidine; Histidine Ammonia-Lyase; Hydrazines; Kinetics; Liver; Male; Organ Specificity; Phenobarbital; Rats; Structure-Activity Relationship

1976
[Enzyme induction in the liver].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1976, Volume: 36, Issue:3-4

    Topics: Animals; Enzyme Induction; Humans; Hydrazines; Liver; Microsomes, Liver; Oxidoreductases, O-Demethylating; Phenobarbital; Rabbits

1976
Detection of free radical intermediates in the oxidative metabolism of carcinogenic hydrazine derivatives.
    Toxicologic pathology, 1987, Volume: 15, Issue:2

    Topics: Animals; Biotransformation; Carcinogens; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrazines; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains

1987
Relationship between oxidative metabolites of hydrazine and hydrazine-induced mutagenicity.
    Toxicology letters, 1986, Volume: 31, Issue:2

    Topics: Animals; Escherichia coli; Hydrazines; Male; Metyrapone; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains

1986
Carcinogenicity and cocarcinogenicity test of phenobarbital sodium in adult BALB/c mice.
    Tumori, 1986, Apr-30, Volume: 72, Issue:2

    Topics: Animals; Cocarcinogenesis; Female; Hydrazines; Liver Neoplasms, Experimental; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Phenobarbital

1986
Oxidation of hydrazine metabolites formed from isoniazid.
    Clinical pharmacology and therapeutics, 1985, Volume: 38, Issue:5

    Topics: Acetylation; Adult; Carbon Dioxide; Carbon Radioisotopes; Female; Humans; Hydrazines; Isoniazid; Liver; Male; Oxidation-Reduction; Phenobarbital

1985
Effects of rifampicin and phenobarbital on the fate of isoniazid and hydrazine in vivo in rats.
    Toxicology letters, 1985, Volume: 25, Issue:3

    Topics: Acetylation; Animals; Drug Interactions; Hydrazines; Isoniazid; Liver; Male; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Rifampin

1985
Nitroreduction of 5-nitrofuran derivatives by rat liver xanthine oxidase and reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase.
    Biochemical pharmacology, 1974, Dec-15, Volume: 23, Issue:24

    Topics: Acetamides; Allylisopropylacetamide; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Cytochrome c Group; Cytochrome Reductases; Cytosol; Dialysis; Electron Transport; Female; Hydrazines; In Vitro Techniques; Liver; Methylcholanthrene; Microsomes, Liver; Milk; NADP; Nitrofurans; Nitrofurantoin; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Thiazoles; Xanthine Oxidase

1974
Seizure susceptibility after manipulation of brain serotonin.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood-Brain Barrier; Brain; Drug Antagonism; Fenclonine; Hydrazines; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Serotonin

1970
The mechanism of halothane binding to microsomal cytochrome P450.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 285, Issue:4

    Topics: Animals; Azo Compounds; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Ethylamines; Halothane; Hydrazines; Ligands; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Spectrophotometry

1974
Oxidative demethylation of N-methylhydrazines by rat liver microsomes.
    Archives of biochemistry and biophysics, 1969, Volume: 134, Issue:2

    Topics: Animals; Azo Compounds; Bile Acids and Salts; Carbon Monoxide; Cytochromes; Formaldehyde; Hot Temperature; Hydrazines; In Vitro Techniques; Lipase; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen Consumption; Pancreatic Juice; Phenobarbital; Proadifen; Rats

1969
Effects of psychoactive drugs on sperm motility.
    Research communications in chemical pathology and pharmacology, 1970, Volume: 1, Issue:2

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Anura; Calcium; Carbohydrates; Cell Movement; Chlordiazepoxide; Chlorpromazine; Depression, Chemical; Dextroamphetamine; Glutamates; Glutathione; Hydrazines; Lipids; Magnesium; Male; Phenobarbital; Phenothiazines; Piperidones; Rana pipiens; Spermatozoa; Sulfoxides; Tranylcypromine; Trifluoperazine

1970
1,1-dimethylhydrazine effects on central excitatory and inhibitory mechanisms in cats. AMRL-TR-65-142.
    AMRL-TR. Aerospace Medical Research Laboratories (U.S.), 1965

    Topics: Animals; Behavior; Brain; Cats; Chlorpromazine; Dextroamphetamine; Diencephalon; Electric Stimulation; Hydrazines; Phenobarbital; Reticular Formation; Telencephalon

1965
Further toxicologic studies of acute hydrazine toxicity in mice. SAM-TR-66-89.
    [Technical report] SAM-TR. USAF School of Aerospace Medicine, 1966

    Topics: Analgesics; Animals; Bromides; Hydrazines; Hypnotics and Sedatives; Mice; Phenobarbital

1966
N-demethylation of p-(N1-methylhydrazion methyl)-N-isopropyl benzamide (procarbazine), a cytostatically active methylhydrazine derivative, in the intact rat and in the isolated perfused rat liver.
    Biochemical pharmacology, 1969, Volume: 18, Issue:9

    Topics: Animals; Benzoates; Carbon Dioxide; Carbon Isotopes; Hydrazines; Liver; Male; Methylation; Methylcholanthrene; Oxidation-Reduction; Perfusion; Phenobarbital; Proadifen; Rats

1969
Pyridoxine and phenobarbital as treatment for aerozine-50 toxicity.
    Aerospace medicine, 1970, Volume: 41, Issue:1

    Topics: Animals; Fossil Fuels; Hydrazines; Hydrochloric Acid; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Phenobarbital; Pyridoxine

1970
Further evidene on the nature of microsomal metabolism of procarbazine and related alkyhydrazines.
    Archives of biochemistry and biophysics, 1970, Volume: 140, Issue:2

    Topics: Animals; Benzoates; Carbon Monoxide; Cytochromes; Enzyme Induction; Hydrazines; Male; Methylcholanthrene; Microsomes, Liver; Nitrogen; Oxidoreductases; Oxygen; Phenobarbital; Proadifen; Rats; Sheep; Swine; Trypsin

1970
[Creatine kinase activity in myocardial infarct].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1965, Dec-06, Volume: 20, Issue:49

    Topics: Creatine Kinase; Humans; Hydrazines; In Vitro Techniques; Myocardial Infarction; Phenobarbital

1965
Demethylation in vivo of Natulan, a tumour-inhibiting methylhydrazine derivative.
    Experientia, 1965, Jun-15, Volume: 21, Issue:6

    Topics: Animals; Antineoplastic Agents; Carbon Dioxide; Hydrazines; Liver; Male; Mice; Phenobarbital; Rats

1965
Acetylhydrazine hepatotoxicity: the role of covalent binding.
    Toxicology, 1984, Feb-14, Volume: 30, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Hydrazines; Liver Diseases; Macromolecular Substances; Male; Necrosis; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Subcellular Fractions

1984
Inhibition of metabolism-mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma (line P815) cells.
    Biochemical pharmacology, 1982, Sep-15, Volume: 31, Issue:18

    Topics: Animals; Biotransformation; Cell Survival; Cells, Cultured; Coumarins; Cyclophosphamide; Hydrazines; Liver; Male; Mast-Cell Sarcoma; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Sarcoma, Experimental

1982
Acetylhydrazine hepatotoxicity.
    Toxicology and applied pharmacology, 1981, Sep-30, Volume: 60, Issue:3

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Hydrazines; Isoniazid; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Rifampin

1981
Cerebral protective effect and radical scavenging action.
    Journal of neurochemistry, 1981, Volume: 37, Issue:4

    Topics: Animals; Ascorbic Acid; Biphenyl Compounds; Brain; Dimethyl Sulfoxide; Hydrazines; Imidazoles; Indicators and Reagents; Lipid Peroxides; Male; Mitochondria; Mitochondria, Liver; Pentobarbital; Phenobarbital; Picrates; Rats; Rats, Inbred Strains

1981
Factors affecting acetylhydrazine hepatotoxicity.
    Advances in experimental medicine and biology, 1981, Volume: 136 Pt B

    Topics: Animals; Cytochrome P-450 Enzyme System; Hydrazines; Isoniazid; Liver; Male; Necrosis; Phenobarbital; Rats; Rats, Inbred Strains

1981
Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1).
    Biochimica et biophysica acta, 1995, Apr-13, Volume: 1243, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Enzyme Induction; Ethanol; Free Radicals; Humans; Hydrazines; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Oxidoreductases, N-Demethylating; Phenobarbital; Pyridines; Rats; Rats, Sprague-Dawley; Spin Labels

1995
Effects of ascorbic acid on iproniazid-induced hepatitis in phenobarbital-treated rats.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:8

    Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Hydrazines; Iproniazid; Kinetics; Liver; Liver Function Tests; Male; Phenobarbital; Rats; Rats, Wistar

1994
Influence of inducers and inhibitors of cytochrome P450 on the hepatotoxicity of hydrazine in vivo.
    Archives of toxicology, 1994, Volume: 68, Issue:6

    Topics: Acetone; Adenosine Triphosphate; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutathione; Hydrazines; Isoniazid; Liver; Male; Phenobarbital; Piperonyl Butoxide; Rats; Rats, Sprague-Dawley; Triglycerides

1994
Induction of megamitochondria by some chemicals inducing oxidative stress in primary cultured rat hepatocytes.
    Biochimica et biophysica acta, 1997, Nov-30, Volume: 1349, Issue:3

    Topics: Animals; Bromobenzenes; Cell Survival; Cells, Cultured; Cycloheximide; Cytochrome P-450 Enzyme System; Erythromycin; Free Radicals; Hydrazines; Hydrogen Peroxide; Lipid Peroxides; Liver; Male; Malondialdehyde; Microscopy, Confocal; Microscopy, Electron; Mitochondria, Liver; Oxidative Stress; Phenobarbital; Protein Synthesis Inhibitors; Rats; Rats, Wistar

1997
Drug-induced alterations of the sub-cellular distribution of 5-hydroxytryptamine (serotonin) in rat's brain.
    Biochemical pharmacology, 1962, Volume: 9

    Topics: Animals; Brain; Chlorpromazine; Dihydroxyphenylalanine; Hydrazines; Hypnotics and Sedatives; Imipramine; Iproniazid; Lysergic Acid Diethylamide; Phenobarbital; Rats; Reserpine; Serotonin

1962
[PHARMACOLOGICAL STUDIES ON GUANETHIDINE DERIVATIVES. II. EFFECTS OF SOME DRUGS ON HYPOTENSIVE ACTION OF GUANETHIDINE AND (2-(HEXAHYDRO-1-AZEPINYL)ETHYL)GUANIDINE SULFATE].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1964, Volume: 84

    Topics: Antihypertensive Agents; Blood Pressure; Chloralose; Cocaine; Epinephrine; Guanethidine; Guanidine; Hydrazines; Norepinephrine; Pentobarbital; Pharmacology; Phenobarbital; Rats; Research; Reserpine; Secobarbital; Sympathomimetics; Thiopental; Tyramine; Urethane

1964
THE ROLE OF ENDOGENOUS NOREPINEPHRINE IN THE TOXICITY OF D-AMPHETAMINE IN AGGREGATED MICE.
    The Journal of pharmacology and experimental therapeutics, 1964, Volume: 144

    Topics: Atropine; Brain Chemistry; Bretylium Compounds; Chlorpromazine; Dextroamphetamine; Hydrazines; Iproniazid; Isoproterenol; Metabolism; Metaraminol; Mice; Myocardium; Norepinephrine; Pharmacology; Phenobarbital; Phenoxybenzamine; Research; Reserpine; Scopolamine; Toxicology

1964
THE SUBCELLULAR LOCALIZATION OF BRAIN-STEM NOREPINEPHRINE AND 5-HYDROXYTRYPTAMINE IN STRESSED RATS.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Brain Stem; Electricity; Electrons; Hydrazines; Microscopy; Microscopy, Electron; Microscopy, Electron, Scanning Transmission; Neurochemistry; Norepinephrine; Pharmacology; Phenobarbital; Rats; Research; Serotonin; Stress, Physiological

1964
THE EFFECT OF PERIODIC CONVULSIONS INDUCED BY 1,1-DIMETHYLHYDRAZINE ON THE GLYCOGEN OF RAT BRAIN.
    Journal of neurochemistry, 1965, Volume: 12

    Topics: Brain; Brain Chemistry; Dimethylhydrazines; Glycogen; Hydrazines; Pharmacology; Phenobarbital; Phosphotransferases; Pyridoxine; Rats; Research; Seizures; Toxicology

1965