phenobarbital and folic acid

phenobarbital has been researched along with folic acid in 92 studies

Research

Studies (92)

Timeframe	Studies, this research(%)	All Research%
pre-1990	77 (83.70)	18.7374
1990's	5 (5.43)	18.2507
2000's	4 (4.35)	29.6817
2010's	5 (5.43)	24.3611
2020's	1 (1.09)	2.80

Authors

Authors	Studies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Fedotova, OI; Frol'kis, AV	1
Nuttall, FQ; Shafer, RB	1
Rising, TJ	1
Bérubé, L; Botez, MI; Labrecque, R; Peyronnard, JM	1
Kelly, D; Reed, B; Scott, J; Weir, D	1
Bill, P; Buchanan, N; Eyberg, C; Fernandes Costa, F; Moodley, GP; Strickwold, B	1
Saunders, J; Wickramasinghe, SN; Williams, G	1
Cameron, JD; Eastham, RD; Jancar, J	1
Aderet, NB; Biale, Y; Lewenthal, H	1
Chen, CP; Wagner, C	1
Chadwick, D; Chanarin, I; Jenner, P; Reynolds, EH	1
Battino, M; Bovina, C; Formiggini, G; Marchetti, M; Sassi, S	1
Bovina, C; Formiggini, G; Marchetti, M; Sassi, S	1
Forth, W; Overhoff, H; Strugala, GJ	1
Bailey, LB; Cerda, JJ; Collins, CS; Hillier, S; Wilder, BJ	1
Bovina, C; Formiggini, G; Marchetti, M; Marchi-Marchetti, M	3
Baylis, EM; Crowley, JM; Marks, V; Preece, JM; Sylvester, PE	1
Reynolds, EH	4
Duchen, L; Harris, R; Marsden, CD; Parsons, V; Reynolds, EH	1
Matthews, DM; Reynolds, EH	1
Chanarin, I; Matthews, DM; Reynolds, EH	1
Fehling, C; Jägerstad, M; Lindstrand, K; Westesson, AK	1
Leary, PM	1
Kiorboe, E; Plum, CM	1
Taguchi, H	2
Eisen, AA; Sherwin, AL; Woods, JF	1
Fenton, GM; Laundy, M; Reynolds, EH; Slavin, BN	1
Hollatz, R; Tempel, K	1
Hilgartner, MW; Kutt, H; Solomon, GE	1
Spector, RG	2
Gallagher, BB; Glass, D; Mattson, RH; Reynolds, EH	1
Gallagher, BB; Mattson, RH; Reynolds, EH	1
Racusen, LC; Smith, DB	1
Baxter, MG; Miller, AA; Webster, RA	1
Henriksen, O; Loyning, Y	1
Heischkeil, R	1
Belsham, A; Higgins, G; Hutt, SJ; Jackson, PM	1
Jensen, ON; Olesen, OV	3
Burns, DG; Spray, GH	1
Kolodziej, A; Radomska, M; Wierzbowska, A	1
Davis, RE; Woodliff, HJ	1
Johnson, AL; Preece, J; Reynolds, EH	1
Bracchetti, A; Giannì, E	1
Hommes, OR; Houben, PF; Knaven, PJ	1
Pritchard, JA; Scott, DE; Whalley, PJ	1
Miller, DR	1
Gordon, N	1
Dyer, AM; Hill, R; Rowan, RM; Taylor, WO	1
Hosokawa, K; Kugoh, T	1
Carl, GF; Smith, DB	1
Bardy, AH; Granström, ML; Hiilesmaa, VK; Teramo, K	1
Billings, RE	1
Blair, JA; Guest, AE; Pheasant, AE; Saleh, AM	1
Richens, A	1
Boldarov, AI; Gvirtsman, LE; Maĭzelis, MIa; Vaĭntrub, MIa; Zabludovskiĭ, AL	1
Evans, MA	1
Bailey, LB; Enneking-Ivey, O; Gawley, L; Hananian, J; Hurd, R	1
Ravakhah, K; West, BC	1
Botez, MI; Botez, T; Lalonde, R; Ross-Chouinard, A	1
Eguchi, T; Fujita, N; Kishi, T; Ueda, K	1
Fiehn, W; Kohl, B; Rieser, PA; Ringleb, P; Schwaninger, M; Walter-Sack, I; Winter, R	1
Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE	1
CHANARIN, I; LAIDLAW, J; LOUGHRIDGE, LW; MOLLIN, DL	1
ULMER, F	1
CHALMERS, JN; HORSFIELD, GI	1
KLIPSTEIN, FA	1
LAUTER, WM	1
ANAND, MP	1
RYDER, RJ	1
HANSEN, HA; NORDQVIST, P; SOURANDER, P	1
DEVERDIER, CH; HAMFELT, A; KILLANDER, A; MALERS, E	1
Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE	1
Aguglia, U; Belcastro, V; Caccamo, D; Calabresi, P; Ciampa, C; Costa, C; Gorgone, G; Ientile, R; Marciani, MG; Oteri, G; Pisani, F; Pisani, LR; Striano, P; Striano, S	1
Alexander, JM; Wilson, KL	1
Biliaminu, SA; N Adeboye, MA; Ojuawo, A; Omefe, PN	1

Reviews

5 review(s) available for phenobarbital and folic acid

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Anticonvulsants, folic acid, and epilepsy. Lancet (London, England), 1973, Jun-16, Volume: 1, Issue:7816 Topics: Anemia, Macrocytic; Animals; Anticonvulsants; Blood-Brain Barrier; Chemical Phenomena; Chemistry; Epilepsies, Partial; Epilepsy; Folic Acid; Humans; Leucovorin; Mice; Phenobarbital; Phenytoin; Primidone; Rabbits; Rats; Seizures	1973
Cerebrospinal folate levels in epileptics and their response to folate therapy. Nutrition reviews, 1974, Volume: 32, Issue:3 Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12	1974
Osteomalacia and anticonvulsant drugs. Nutrition reviews, 1971, Volume: 29, Issue:2 Topics: Alkaline Phosphatase; Anticonvulsants; Calcium; Epilepsy; Folic Acid; Humans; Liver; Osteomalacia; Phenobarbital; Phenytoin; Primidone; Vitamin D	1971
Seizures and intracranial hemorrhage. Obstetrics and gynecology clinics of North America, 2013, Volume: 40, Issue:1 Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K	2013

Trials

6 trial(s) available for phenobarbital and folic acid

Article	Year
Influence of folic acid on blood-phenytoin levels. Lancet (London, England), 1971, Jan-09, Volume: 1, Issue:7689 Topics: Adult; Anticonvulsants; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenobarbital; Phenytoin; Primidone	1971
Folate therapy in epilepsy. A controlled study. Archives of neurology, 1973, Volume: 29, Issue:2 Topics: Clinical Trials as Topic; Cognition; Epilepsy; Evaluation Studies as Topic; Folic Acid; Humans; Leucovorin; Personality; Phenobarbital; Phenytoin; Primidone; Psychological Tests	1973
Cerebrospinal folate levels in epileptics and their response to folate therapy. Nutrition reviews, 1974, Volume: 32, Issue:3 Topics: Anticonvulsants; Blood-Brain Barrier; Clinical Trials as Topic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Tetrahydrofolates; Vitamin B 12	1974
Perceptual-motor behaviour in relation to blood phenobarbitone level: a preliminary report. Developmental medicine and child neurology, 1968, Volume: 10, Issue:5 Topics: Adult; Blood Cell Count; Blood Pressure; Clinical Trials as Topic; Electroencephalography; Female; Folic Acid; Humans; Male; Motor Activity; Perception; Phenobarbital; Placebos; Speech; Vitamin B 12	1968
Subnormal serum folate due to anticonvulsive therapy. A double-blind study of the effect of folic acid treatment in patients with drug-induced subnormal serum folates. Archives of neurology, 1970, Volume: 22, Issue:2 Topics: Adult; Anticonvulsants; Clinical Trials as Topic; Epilepsy; Erythrocyte Count; Female; Folic Acid; Hematocrit; Hemoglobinometry; Humans; Male; Phenobarbital; Phenytoin; Placebos; Primidone	1970
Thiamine and folate treatment of chronic epileptic patients: a controlled study with the Wechsler IQ scale. Epilepsy research, 1993, Volume: 16, Issue:2 Topics: Adult; Brain; Double-Blind Method; Drug Therapy, Combination; Education; Electroencephalography; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thiamine; Vitamin B 12; Wechsler Scales	1993

Other Studies

82 other study(ies) available for phenobarbital and folic acid

Article	Year
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
[Effect of various drugs on membrane digestion]. Klinicheskaia meditsina, 1979, Volume: 57, Issue:7 Topics: Aminophylline; Depression, Chemical; Digestion; Ephedrine; Folic Acid; Humans; Intestinal Mucosa; Jejunum; Levodopa; Nandrolone; Phenobarbital; Prednisolone; Prenylamine; Stimulation, Chemical; Sulfasalazine	1979
Calcium and folic acid absorption in patients taking anticonvulsant drugs. The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:06 Topics: Adult; Aged; Calcium; Cholecalciferol; Epilepsy; Folic Acid; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Rickets; Time Factors	1975
Effects of hepatic microsomal enzyme inducers of the endogenous substrates vitamin D3 and folate in rat. Biochemical pharmacology, 1979, Volume: 28, Issue:1 Topics: Animals; Anticonvulsants; Body Weight; Cholecalciferol; Enzyme Induction; Folic Acid; Formiminoglutamic Acid; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Phenylbutyrates; Rats; Urea	1979
Relapsing neuropathy, cerebral atrophy and folate deficiency. A close association. Applied neurophysiology, 1979, Volume: 42, Issue:3 Topics: Atrophy; Brain Diseases; Edema; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Diseases; Jejunum; Middle Aged; Paralysis; Phenobarbital; Primidone; Radial Nerve; Restless Legs Syndrome; Syndrome	1979
Effect of anticonvulsant drugs on the rate of folate catabolism in mice. The Journal of clinical investigation, 1979, Volume: 64, Issue:4 Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Female; Folic Acid; Male; Mice; Phenobarbital; Phenytoin; Pteroylpolyglutamic Acids	1979
Serum levels of anticonvulsants and haematological sequelae in black epileptics. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1977, Apr-09, Volume: 51, Issue:15 Topics: Adolescent; Adult; Aged; Black People; Child; Child, Preschool; Drug Combinations; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone	1977
Effects of anticonvulsant drugs on the synthesis of DNA and protein by human bone marrow cells in vitro. Scandinavian journal of haematology, 1976, Volume: 17, Issue:4 Topics: Bone Marrow; Bone Marrow Cells; DNA; Folic Acid; Humans; Leucine; Leucovorin; Phenobarbital; Phenytoin; Protein Biosynthesis; Thymidine	1976
Red cell folate and macrocytosis during long-term anticonvulsant therapy in non-anaemic mentally. Retarded epileptics. The British journal of psychiatry : the journal of mental science, 1975, Volume: 126 Topics: Dose-Response Relationship, Drug; Epilepsy; Erythrocytes; Erythrocytes, Abnormal; Female; Folic Acid; Folic Acid Deficiency; Hematocrit; Humans; Intellectual Disability; Male; Phenobarbital; Time Factors; Yeast, Dried	1975
Congenital malformations due to anticonvulsive drugs. Obstetrics and gynecology, 1975, Volume: 45, Issue:4 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adult; Anencephaly; Anticonvulsants; Birth Order; Cleft Lip; Cleft Palate; Epilepsy; Female; Fetal Death; Folic Acid; Folic Acid Antagonists; Hemorrhage; Humans; Infant, Newborn; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Trimethadione	1975
Folate transport in the choroid plexus. Life sciences, 1975, May-15, Volume: 16, Issue:10 Topics: Animals; Biological Transport; Choroid Plexus; Dinitrophenols; Folic Acid; In Vitro Techniques; Kinetics; Oxygen; Phenobarbital; Phenytoin; Probenecid; Sodium; Swine; Tetrahydrofolates	1975
Folate and monoamine metabolism in epilepsy. Journal of the neurological sciences, 1975, Volume: 26, Issue:4 Topics: Adolescent; Adult; Anticonvulsants; Biogenic Amines; Epilepsy; Erythrocytes; Folic Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenobarbital; Phenytoin; Primidone; Vitamin B 12	1975
Changes in hepatic folylpolyglutamate pattern in phenobarbitone-treated rats. Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12 Topics: Animals; Chromatography, High Pressure Liquid; Folic Acid; Injections, Intraperitoneal; Liver; Male; Phenobarbital; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains	1990
Liver cytosolic protein-bound folates in phenobarbitone-treated rats. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1987, Volume: 57, Issue:4 Topics: Animals; Carrier Proteins; Chromatography, Gel; Cytosol; Folate Receptors, GPI-Anchored; Folic Acid; Liver; Male; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Receptors, Cell Surface	1987
Bidirectional transfer and tissue accumulation of folic acid by rat intestine in vitro. Digestion, 1985, Volume: 32, Issue:4 Topics: Animals; Biological Transport; Colon; Duodenum; Female; Folic Acid; Ileum; Intestinal Mucosa; Jejunum; Kinetics; Phenobarbital; Rats; Rats, Inbred Strains; Sulfasalazine; Temperature; Tritium	1985
Red blood cell uptake of supplemental folate in patients on anticonvulsant drug therapy. The American journal of clinical nutrition, 1988, Volume: 48, Issue:6 Topics: Adult; Anticonvulsants; Erythrocytes; Folic Acid; Food, Fortified; Humans; Male; Phenobarbital; Phenytoin	1988
The time course of [3H]PteGlu uptake and its incorporation into pteroylpolyglutamates in liver of phenobarbitone treated rats. Pharmacological research communications, 1985, Volume: 17, Issue:2 Topics: Animals; Folic Acid; Liver; Male; Phenobarbital; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains; Time Factors	1985
Myopathy associated with anticonvulsant osteomalacia. British medical journal, 1973, Dec-01, Volume: 4, Issue:5891 Topics: Adult; Anticonvulsants; Back Pain; Depression; Electroencephalography; Electromyography; Ergocalciferols; Female; Folic Acid; Hemoglobins; Humans; Intelligence; Microscopy, Electron; Muscular Diseases; Osteomalacia; Paralysis; Phenobarbital; Phenytoin; Thiazines; Vitamin D	1973
Gastrointestinal function in anticonvulsant megaloblastic anaemia. Lancet (London, England), 1966, Jan-22, Volume: 1, Issue:7430 Topics: Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Vitamin B 12	1966
Effects of folic acid on the mental state and fit-frequency of drug-treated epileptic patients. Lancet (London, England), 1967, May-20, Volume: 1, Issue:7499 Topics: Adolescent; Adult; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Follow-Up Studies; Humans; Male; Mental Health; Middle Aged; Phenobarbital; Phenytoin; Primidone	1967
Neuropsychiatric aspects of anticonvulsant megaloblastic anaemia. Lancet (London, England), 1968, Feb-24, Volume: 1, Issue:7539 Topics: Acetazolamide; Adult; Anemia, Macrocytic; Epilepsy; Female; Folic Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychophysiologic Disorders; Thiazines; Vitamin B 12	1968
The effect of anticonvulsant therapy upon the absorption of folates. Clinical science, 1973, Volume: 44, Issue:6 Topics: Adult; Aged; Anticonvulsants; Biological Assay; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Lacticaseibacillus casei; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone	1973
Folate studies in underprivileged children with epilepsy. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Nov-24, Volume: 47, Issue:46 Topics: Anticonvulsants; Biological Assay; Child; Child, Preschool; Epilepsy; Euglena; Folic Acid; Hematocrit; Hemoglobins; Humans; Lacticaseibacillus casei; Leukocyte Count; Phenobarbital; Phenytoin; Primidone; Vitamin B 12	1973
Megaloblastic anaemia developing during treatment of epilepsy. Acta medica Scandinavica. Supplementum, 1966, Volume: 445 Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Blood; Epilepsy; Folic Acid; Hemoglobins; Humans; Huntington Disease; In Vitro Techniques; Male; Phenobarbital	1966
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. I. Clinical and nutritional study on megalobastic anemia due to anticonvulsants. Acta medicinae Okayama, 1971, Volume: 25, Issue:5 Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Diet; Epilepsy, Temporal Lobe; Folic Acid; Folic Acid Deficiency; Food Analysis; Humans; Male; Phenobarbital; Phenytoin	1971
Clinical and experimental studies on folic acid deficiency due to anticonvulsants. 2. Investigations on patients receiving anticonvulsants and experimental study on the effect of diphenylhydantoin on the absorption of folic acid in rats. Acta medicinae Okayama, 1971, Volume: 25, Issue:5 Topics: Adolescent; Adult; Animals; Anticonvulsants; Cell Nucleus; Depression, Chemical; Epithelial Cells; Female; Folic Acid; Folic Acid Deficiency; Humans; Intestinal Absorption; Intestine, Small; Iron; Kidney; Leukocyte Count; Liver; Male; Middle Aged; Mouth Mucosa; Neutrophils; Phenobarbital; Phenytoin; Primidone; Rats; Tritium; Vitamin B 12	1971
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation. Neurology, 1974, Volume: 24, Issue:5 Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked Potentials; Female; Folic Acid; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Reaction Time; Reflex, Monosynaptic; Sural Nerve; Time Factors; Vitamin B 12	1974
Iatrogenic disorders in epilepsy. Modern trends in neurology, 1970, Volume: 5, Issue:0 Topics: Adrenal Insufficiency; Anemia, Macrocytic; Animals; Anticonvulsants; Cats; Cerebellar Diseases; Drug Therapy, Combination; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Hypothyroidism; Metabolic Diseases; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Rats; Rickets; Seizures	1970
Serum immunoglobulins in epilepsy. Journal of the neurological sciences, 1974, Volume: 23, Issue:3 Topics: Adult; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Folic Acid; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Male; Phenobarbital; Phenytoin; Primidone	1974
[Induction effects in the mouse under the influence of polyanions]. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 210, Issue:1 Topics: Aniline Compounds; Animals; Carbon Radioisotopes; Dactinomycin; DNA; Enzyme Induction; Female; Folic Acid; In Vitro Techniques; Kidney; Mice; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Orotic Acid; Phenobarbital; Phenylalanine; Polysaccharides; Protein Biosynthesis; RNA; Sulfuric Acids	1974
Phenobarbital-induced coagulation defects in cats. Neurology, 1974, Volume: 24, Issue:10 Topics: Alanine Transaminase; Animals; Animals, Newborn; Blood Coagulation; Blood Coagulation Disorders; Cats; Depression, Chemical; Dose-Response Relationship, Drug; Drug Interactions; Factor V Deficiency; Factor VII; Factor VII Deficiency; Female; Folic Acid; Hemophilia A; Hypoprothrombinemias; Liver; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Rats; Vitamin K	1974
Effects of formyl tetrahydrofolic acid and noradrenaline on the oxygen consumption of rat brain synaptosome-mitochondrial preparations. British journal of pharmacology, 1972, Volume: 44, Issue:2 Topics: Acetylcholine; Animals; Cerebral Cortex; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Folic Acid; Histamine; Isoproterenol; Kinetics; Leucovorin; Microsomes; Models, Structural; Norepinephrine; Oxygen Consumption; Phenobarbital; Prochlorperazine; Rats; Synaptosomes	1972
Clinical conference: megaloblastic anemia associated with anticonvulsant drugs. Journal of the Tennessee Medical Association, 1972, Volume: 65, Issue:9 Topics: Adult; Anemia, Macrocytic; Anticonvulsants; Female; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone	1972
Relationships between serum and cerebrospinal fluid anticonvulsant drug and folic acid concentrations in epileptic patients. Neurology, 1972, Volume: 22, Issue:8 Topics: Adult; Chromatography, Gas; Epilepsy; Female; Folic Acid; Humans; Male; Phenobarbital; Phenytoin; Primidone	1972
Folate metabolism and the anticonvulsant efficacy of phenobarbital. Archives of neurology, 1973, Volume: 28, Issue:1 Topics: Animals; Disease Models, Animal; Flurothyl; Folic Acid; Folic Acid Deficiency; Male; Phenobarbital; Rats; Seizures; Vitamin B 12	1973
Some studies on the convulsant action of folic acid. British journal of pharmacology, 1973, Volume: 48, Issue:2 Topics: Alkaloids; Animals; Auditory Threshold; Cerebral Ventricles; Dioxoles; Electroshock; Folic Acid; Folic Acid Antagonists; Glutamates; Injections; Injections, Intravenous; Isoquinolines; Mice; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Seizures; Strychnine	1973
[Editorial: Antiepileptic agents--folic acid]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Jun-30, Volume: 93, Issue:18 Topics: Anemia, Macrocytic; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Vitamin B 12	1973
[Antimetabolites of folic acid metabolism with chemotherapeutic activity against rodent malaria (Plasmodium vinckei)]. Zeitschrift fur Tropenmedizin und Parasitologie, 1973, Volume: 24, Issue:4 Topics: Aminopterin; Animals; Cycloheximide; Female; Folic Acid; Folic Acid Antagonists; Hydantoins; Malaria; Male; Methotrexate; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Plasmodium; Primidone; Pyrimethamine; Thalidomide; Triamterene	1973
Folate deficiency and anticonvulsant drugs. British medical journal, 1972, Apr-15, Volume: 2, Issue:5806 Topics: Animals; Enzyme Induction; Female; Folic Acid; Folic Acid Deficiency; Liver; Male; Oxidoreductases; Phenobarbital; Phenytoin; Rats; Transferases	1972
[Hematological control in the treatment of epilepsy]. Neurologia i neurochirurgia polska, 1971, Volume: 5, Issue:3 Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Child; Epilepsy; Female; Folic Acid; Hematologic Diseases; Hematopoietic System; Humans; Hydantoins; Leukopenia; Male; Middle Aged; Phenobarbital; Primidone	1971
Folic acid deficiency in patients receiving anticonvulsant drugs. The Medical journal of Australia, 1971, Nov-20, Volume: 2, Issue:21 Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Middle Aged; Phenobarbital	1971
Folic acid concentrations in cerebrospinal fluid in relation to anticonvulsant drugs and cerebral atrophy. Acta psychiatrica Scandinavica, 1971, Volume: 47, Issue:2 Topics: Adult; Anticonvulsants; Atrophy; Brain Diseases; Epilepsy; Female; Folic Acid; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenytoin; Pneumoencephalography	1971
Influence of folic acid on noradrenaline stimulation of rat brain synaptosomes. British journal of pharmacology, 1971, Volume: 43, Issue:2 Topics: Animals; Brain; Epinephrine; Fluorouracil; Folic Acid; Folic Acid Antagonists; In Vitro Techniques; Nerve Endings; Norepinephrine; Oxygen Consumption; Phenobarbital; Rats; Synaptic Vesicles; Synaptosomes	1971
Folate metabolism in epileptic and psychiatric patients. Journal of neurology, neurosurgery, and psychiatry, 1971, Volume: 34, Issue:6 Topics: Adult; Antidepressive Agents; Epilepsy; Erythrocytes; Female; Folic Acid; Folic Acid Deficiency; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Phenothiazines; Phenytoin; Vitamin B 12	1971
[Contribution to the pathogenesis of gingival hypertrophy due to diphenylhydantoin in experiments on animals]. Minerva stomatologica, 1968, Volume: 17, Issue:6 Topics: Anemia; Animals; Drug Synergism; FIGLU Test; Folic Acid; Gingival Hypertrophy; Phenobarbital; Phenytoin; Rats	1968
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q. Epilepsia, 1971, Volume: 12, Issue:3 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Phenobarbital; Phenytoin; Primidone; Prognosis	1971
Maternal folate deficiency and pregnancy wastage. IV. Effects of folic acid supplements, anticonvulsants, and oral contraceptives. American journal of obstetrics and gynecology, 1971, Feb-01, Volume: 109, Issue:3 Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Anemia, Macrocytic; Anemia, Sickle Cell; Anemia, Sideroblastic; Anticonvulsants; Birth Weight; Contraceptives, Oral; Drug Antagonism; Epilepsy; Female; Fetus; Folic Acid; Folic Acid Antagonists; Folic Acid Deficiency; Hemoglobinometry; Humans; Hypertension; Infant Mortality; Infant, Newborn; Infant, Premature; Iron; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications	1971
Serum folate deficiency in children receiving anticonvulsant therapy. Pediatrics, 1968, Volume: 41, Issue:3 Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Child; Child, Preschool; Epilepsy; Erythrocyte Count; Folic Acid; Folic Acid Deficiency; Hematocrit; Hemoglobinometry; Humans; Phenobarbital; Phenytoin	1968
Folic acid deficiency from anticonvulsant therapy. Developmental medicine and child neurology, 1968, Volume: 10, Issue:4 Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Male; Mental Processes; Phenobarbital; Phenytoin; Primidone; Protein Biosynthesis	1968
Mental effects of anticonvulsants, and folic acid metabolism. Brain : a journal of neurology, 1968, Volume: 91, Issue:2 Topics: Age Factors; Anemia, Macrocytic; Anticonvulsants; Brain; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Intellectual Disability; Male; Mental Disorders; Peripheral Nerves; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Sex Factors; Spinal Cord; Vitamin B 12	1968
Folic acid and anticonvulsive drugs. Archives of neurology, 1969, Volume: 21, Issue:2 Topics: Adolescent; Adult; Anticonvulsants; Epilepsy; Erythrocyte Count; Female; FIGLU Test; Folic Acid; Folic Acid Deficiency; Hematocrit; Humans; Male; Middle Aged; Neutrophils; Phenobarbital; Phenytoin; Primidone; Psychotic Disorders; Vitamin B 12	1969
Case of tuberous sclerosis and haemorrhagic retinopathy (with fundus photographs). British medical journal, 1967, Nov-18, Volume: 4, Issue:5576 Topics: Adult; Amphetamine; Anemia, Macrocytic; Female; Folic Acid; Fundus Oculi; Humans; Phenobarbital; Phenytoin; Photography; Retinal Hemorrhage; Seizures; Tuberous Sclerosis	1967
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy. Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:3 Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12	1983
Effect of chronic phenobarbital treatment on folates and one-carbon enzymes in the rat. Biochemical pharmacology, 1984, Nov-01, Volume: 33, Issue:21 Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase (FADH2); Alcohol Oxidoreductases; Animals; Brain; Folic Acid; Glycine Hydroxymethyltransferase; Liver; Male; Methionine Adenosyltransferase; Methyltransferases; Phenobarbital; Rats; Rats, Inbred Strains; Transferases	1984
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome. British medical journal (Clinical research ed.), 1983, Aug-27, Volume: 287, Issue:6392 Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications	1983
Interactions between folate metabolism, phenytoin metabolism, and liver microsomal cytochrome P450. Drug-nutrient interactions, 1984, Volume: 3, Issue:1 Topics: Animals; Diet; Folic Acid; Folic Acid Deficiency; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains	1984
Effects of phenobarbitone and phenytoin on folate catabolism in the rat. Biochemical pharmacology, 1983, Nov-01, Volume: 32, Issue:21 Topics: Animals; Chemical Phenomena; Chemistry; Feces; Folic Acid; Kidney; Liver; Male; Phenobarbital; Phenytoin; Rats	1983
Pteroylpolyglutamates in liver of phenobarbitone-treated rats. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1983, Volume: 53, Issue:4 Topics: Animals; Folic Acid; Liver; Male; Phenobarbital; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains	1983
Effect of phenobarbitone on folic acid metabolism in the rat. Pharmacological research communications, 1984, Volume: 16, Issue:5 Topics: Animals; Folic Acid; Kidney; Liver; Male; Phenobarbital; Pteroylpolyglutamic Acids; Rats; Rats, Inbred Strains	1984
Pharmacokinetics of anticonvulsant drugs. Acta neurologica Scandinavica. Supplementum, 1980, Volume: 80 Topics: Anticonvulsants; Binding, Competitive; Brain; Carbamazepine; Drug Interactions; Drug Tolerance; Epilepsy; Folic Acid; Humans; Kinetics; Phenobarbital; Phenytoin; Protein Binding; Tissue Distribution; Valproic Acid	1980
[Radioimmunologic study of the plasma concentrations of folic acid and various antiepileptic preparations during the treatment of epileptic patients]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1983, Volume: 83, Issue:6 Topics: Adolescent; Adult; Anticonvulsants; Benzamidines; Drug Therapy, Combination; Epilepsy; Female; Folic Acid; Humans; Male; Phenobarbital; Phenytoin; Radioimmunoassay	1983
Effects of anticonvulsants and methotrexate on calcium disposition. Naunyn-Schmiedeberg's archives of pharmacology, 1980, Volume: 315, Issue:1 Topics: Animals; Anticonvulsants; Calcium; Calcium Radioisotopes; Folic Acid; Intestinal Absorption; Male; Methotrexate; Mice; Phenobarbital; Phenytoin	1980
Folic acid and vitamin D status of young children receiving minimal anticonvulsant drug therapy. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1981, Volume: 51, Issue:4 Topics: Alkaline Phosphatase; Calcium; Child, Preschool; Female; Folic Acid; Hematocrit; Humans; Male; Nutritional Physiological Phenomena; Nutritional Requirements; Phenobarbital; Phenytoin; Phosphorus; Seizures; Vitamin D	1981
Case report: subacute combined degeneration of the spinal cord from folate deficiency. The American journal of the medical sciences, 1995, Volume: 310, Issue:5 Topics: Adult; Erythrocyte Transfusion; Folic Acid; Folic Acid Deficiency; Humans; Male; Phenobarbital; Spinal Cord Diseases	1995
Mechanism for reduction of serum folate by antiepileptic drugs during prolonged therapy. Journal of the neurological sciences, 1997, Volume: 145, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Demography; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Isoxazoles; Male; Phenobarbital; Time Factors; Valproic Acid; Zonisamide	1997
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment. Epilepsia, 1999, Volume: 40, Issue:3 Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency	1999
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs. Acta neurologica Scandinavica, 2000, Volume: 101, Issue:4 Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12	2000
Megaloblastic anaemia due to phenobarbitone; the convulsant action of therapeutic doses of folic acid. British medical journal, 1960, Apr-09, Volume: 1, Issue:5179 Topics: Anemia; Anemia, Megaloblastic; Convulsants; Folic Acid; Phenobarbital; Tracheophyta	1960
[The modification of flicker fusion frequency in man by phenylpyrrolidinopentane, Katovit, caffeine and phenylethylbarbituric acid]. Die Medizinische Welt, 1961, Dec-23, Volume: 51 Topics: Ascorbic Acid; Caffeine; Flicker Fusion; Folic Acid; Humans; Male; Phenobarbital; Pyrrolidines; Sympathomimetics; Vitamin B Complex; Vitamins	1961
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT THERAPY. The Practitioner, 1963, Volume: 191 Topics: Amobarbital; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Barbiturates; Epilepsy; Folic Acid; Humans; Metabolism; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12	1963
SUBNORMAL SERUM FOLATE AND MACROCYTOSIS ASSOCIATED WITH ANTICONVULSANT DRUG THERAPY. Blood, 1964, Volume: 23 Topics: Anemia; Anemia, Macrocytic; Anticonvulsants; Biological Assay; Blood Chemical Analysis; Enterococcus faecalis; Epilepsy; Folic Acid; Folic Acid Antagonists; Humans; Lactobacillus; Phenobarbital; Phenytoin; Primidone; Toxicology; Vitamin B 12	1964
OLD AND STILL GOOD. The Journal of the Florida Medical Association. Florida Medical Association, 1964, Volume: 51 Topics: Alkaloids; Aspirin; Digitalis; Digitalis Glycosides; Folic Acid; Hypnotics and Sedatives; Iron; Opium; Pharmacology; Phenobarbital; Rauwolfia; Thyroid Hormones; Vitamin B Complex	1964
IATROGENIC MEGALOBLASTIC ANAEMIA WITH NEUROLOGICAL COMPLICATIONS. Scottish medical journal, 1964, Volume: 9 Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Brain Diseases; Cysticercosis; Drug Therapy; Epilepsy; Folic Acid; Humans; Iatrogenic Disease; Phenobarbital; Phenytoin; Primidone; Spinal Cord; Toxicology; Vitamin B 12	1964
HAEMORRHAGE ASSOCIATED WITH THROMBOCYTOPENIA IN MEGALOBLASTIC ANAEMIA. Journal of the Irish Medical Association, 1964, Volume: 55 Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Blood Platelet Disorders; Drug Therapy; Epilepsy; Female; Folic Acid; Hemorrhage; Humans; Phenobarbital; Pregnancy; Pregnancy Complications; Pregnancy Complications, Hematologic; Primidone; Thrombocytopenia; Toxicology; Vitamin B 12	1964
MEGALOBLASTIC ANEMIA AND NEUROLOGIC DISTURBANCES COMBINED WITH FOLIC ACID DEFICIENCY. OBSERVATIONS ON AN EPILEPTIC PATIENT TREATED WITH ANTICONVULSANTS. Acta medica Scandinavica, 1964, Volume: 176 Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Avitaminosis; Barbiturates; Brain Diseases; Central Nervous System Diseases; Cerebellar Diseases; Drug Therapy; Epilepsy; Folic Acid; Folic Acid Deficiency; Humans; Neurologic Manifestations; Pathology; Phenobarbital; Phenytoin; Spinal Cord; Spinal Nerves; Toxicology; Trimethadione	1964
MEGALOBLASTIC ANAEMIA ASSOCIATED WITH ANTICONVULSANT DRUGS: STUDIES ON A CASE WITH FOUR RELAPSES. Acta medica Scandinavica, 1965, Volume: 177 Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Anticonvulsants; Drug Therapy; Electrophoresis; Epilepsy; FIGLU Test; Folic Acid; Folic Acid Deficiency; Humans; Phenobarbital; Phenytoin; Primidone; Recurrence; Toxicology; Urine	1965
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins. Epilepsy research, 2008, Volume: 82, Issue:1 Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency	2008
Hyperhomocysteinemia in epileptic patients on new antiepileptic drugs. Epilepsia, 2010, Volume: 51, Issue:2 Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Enzyme Induction; Epilepsy; Female; Folic Acid; Fructose; Genotype; Humans; Hyperhomocysteinemia; Lamotrigine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxcarbazepine; Phenobarbital; Polymorphism, Genetic; Topiramate; Triazines; Vitamin B 12	2010
Serum folate levels in children with epilepsy seen in a tertiary health care facility in north central Nigeria. Nigerian journal of clinical practice, 2022, Volume: 25, Issue:10 Topics: Anticonvulsants; Carbamazepine; Child; Cross-Sectional Studies; Delivery of Health Care; Epilepsy; Folic Acid; Humans; Nigeria; Phenobarbital; Quality of Life; Valproic Acid	2022