phenobarbital and ethacrynic acid

phenobarbital has been researched along with ethacrynic acid in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's2 (11.11)18.2507
2000's6 (33.33)29.6817
2010's3 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Seixas, FA1
Clifton, G; Kaplowitz, N; Wallin, JD1
Clifton, G; Kaplowitz, N1
Watkins, JB1
Arias, IM; Fleischner, G; Gatmaitan, Z; Habig, WH; Jakoby, WB; Pabst, MJ1
Greenberger, NJ; Thomas, FB1
Alicino, JF; Hess, SM; Michel, IM; Weinryb, I1
Avner, DL; Berenson, MM1
Cheung, SW; Inaba, T; Shibasaki, M; Shimoda, K; Someya, T; Takahashi, S1
Azémar, B; Beaune, P; El Adlouni, C; Pfohl-Leszkowicz, A; Pinelli, E; Zaoui, D1
Girard, JP; Gnassia-Barelli, M; Hoarau, P; Romeo, M1
Gupta, S; Rathaur, S1

Reviews

2 review(s) available for phenobarbital and ethacrynic acid

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

16 other study(ies) available for phenobarbital and ethacrynic acid

ArticleYear
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Drug/alcohol interactions: avert potential dangers.
    Geriatrics, 1979, Volume: 34, Issue:10

    Topics: Aged; Aging; Alcohol Drinking; Alcoholism; Antidepressive Agents, Tricyclic; Aspirin; California; Diabetic Coma; Drug Interactions; Ethacrynic Acid; Ethanol; Female; Humans; Male; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Washington

1979
The effect of phenobarbital, probenecid and diethyl maleate on the pharmaco-kinetics and biliary excretion of ethacrynic acid in the rat.
    The Journal of pharmacology and experimental therapeutics, 1978, Volume: 205, Issue:2

    Topics: Animals; Bile; Cytosol; Ethacrynic Acid; Glutathione Transferase; Kidney; Kinetics; Liver; Male; Maleates; Metabolic Clearance Rate; Phenobarbital; Probenecid; Protein Binding; Rats

1978
The glutathione S-transferases of the small intestine in the rat.
    Cancer research, 1977, Volume: 37, Issue:3

    Topics: Animals; Benzopyrenes; Carcinogens; Enzyme Induction; Epoxy Compounds; Ethacrynic Acid; Fasting; Glutathione Transferase; Inactivation, Metabolic; Intestine, Small; Kidney; Liver; Male; Methylcholanthrene; Nitrobenzenes; Phenobarbital; Rats

1977
Effect of microsomal enzyme inducing agents on hepatic biotransformation in cotton rats (Sigmodon hispidus): comparison to that in Sprague-Dawley rats.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 98, Issue:2-3

    Topics: Animals; Arylsulfotransferase; Biotransformation; Cytochrome P-450 Enzyme System; Dinitrochlorobenzene; Enzyme Induction; Ethacrynic Acid; Female; Glucuronosyltransferase; Glutathione Transferase; Liver; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Sulfobromophthalein; Sulfotransferases

1991
The identity of glutathione S-transferase B with ligandin, a major binding protein of liver.
    Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:10

    Topics: Animals; Bilirubin; Binding, Competitive; Carrier Proteins; Enzyme Activation; Epitopes; Ethacrynic Acid; Glutathione; Indocyanine Green; Kinetics; Ligands; Liver; Methane; Nitrobenzenes; Phenobarbital; Protein Binding; Rats; Transferases

1974
Biliary excretion of 3 H-digitoxin: modification by bile salts and phenobarbital.
    The Journal of laboratory and clinical medicine, 1973, Volume: 81, Issue:2

    Topics: Animals; Bile; Bile Acids and Salts; Digitoxin; Ethacrynic Acid; Female; Phenobarbital; Rats; Taurocholic Acid; Tritium

1973
Effects of barbiturate derivatives, sulfhydryl reagents, and oxidizing agents on the activity of adenylate cyclase from guinea pig heart and lung.
    Archives of biochemistry and biophysics, 1971, Volume: 146, Issue:2

    Topics: Adenylyl Cyclase Inhibitors; Alloxan; Amobarbital; Animals; Barbiturates; Ethacrynic Acid; Guinea Pigs; Heart Ventricles; Lung; Male; Mephobarbital; Myocardium; Organomercury Compounds; Pentobarbital; Phenobarbital; Pulmonary Alveoli; Pyrrolidinones; Secobarbital; Sulfhydryl Reagents

1971
Effect of choleretics on canalicular transport of protoporphyrin in the rat liver.
    The American journal of physiology, 1982, Volume: 242, Issue:4

    Topics: Animals; Bile; Bile Ducts; Dehydrocholic Acid; Ethacrynic Acid; Liver; Perfusion; Phenobarbital; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Taurocholic Acid

1982
Carbonyl reduction of timiperone in human liver cytosol.
    Pharmacology & toxicology, 1998, Volume: 83, Issue:4

    Topics: Alcohol Oxidoreductases; Antipsychotic Agents; Butyrophenones; Chromatography, High Pressure Liquid; Cytosol; Enzyme Inhibitors; Ethacrynic Acid; Fomepizole; Haloperidol; Humans; In Vitro Techniques; Liver; Phenobarbital; Pyrazoles; Vitamin K

1998
Phenobarbital increases DNA adduct and metabolites formed by ochratoxin A: role of CYP 2C9 and microsomal glutathione-S-transferase.
    Environmental and molecular mutagenesis, 2000, Volume: 35, Issue:2

    Topics: Animals; Antimutagenic Agents; Aryl Hydrocarbon Hydroxylases; Bronchi; Cytochrome P-450 Enzyme System; DNA Adducts; Epithelial Cells; Ethacrynic Acid; Glutathione Transferase; Humans; Kidney; Microsomes; Ochratoxins; Phenobarbital; Rabbits; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases

2000
Differential induction of glutathione S-transferases in the clam Ruditapes decussatus exposed to organic compounds.
    Environmental toxicology and chemistry, 2001, Volume: 20, Issue:3

    Topics: Animals; Antibody Specificity; Benzo(a)pyrene; Bivalvia; Blotting, Western; Cytosol; Dichloroethylenes; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Ethacrynic Acid; Excitatory Amino Acid Antagonists; Glutathione Transferase; Immunoblotting; Organic Chemicals; Phenobarbital

2001
Filarial glutathione S-transferase: its induction by xenobiotics and potential as drug target.
    Acta biochimica Polonica, 2005, Volume: 52, Issue:2

    Topics: Animals; Butylated Hydroxyanisole; Dactinomycin; Diethylcarbamazine; Dinitrochlorobenzene; Electrophoresis, Polyacrylamide Gel; Ellagic Acid; Enzyme Activation; Ethacrynic Acid; Female; Glutathione Transferase; Phenobarbital; Setaria Nematode; Substrate Specificity

2005