phenobarbital and diethylhexyl phthalate

phenobarbital has been researched along with diethylhexyl phthalate in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199010 (35.71)18.7374
1990's12 (42.86)18.2507
2000's3 (10.71)29.6817
2010's3 (10.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aoki, T; Hakoi, K; Ito, N; Kato, T; Ozaki, K; Sato, K; Tsuda, H; Uwagawa, S; Yamaguchi, S1
Carter, HW; Carter, JH; Daniel, FB; DeAngelo, AB; Potter, CL; Richmond, RE1
Dirven, HA; Jongeneelen, FJ; Noordhoek, J; Peters, JG; van den Broek, PH1
Maruyama, H; Tanaka, T; Williams, GM1
Appelkvist, EL; Dallner, G; Kalén, A1
Büsser, MT; Lutz, WK1
Waalkes, MP; Ward, JM1
DeAngelo, AB; Garrett, CT; Irwin, D; Queral, AE1
Anderson, LM; Diwan, BA; Hagiwara, A; Lindsey, K; Ward, JM1
Diwan, BA; Hu, H; Ohshima, M; Rice, JM; Schuller, HM; Ward, JM1
DeAngelo, AB; Garrett, CT; Queral, AE1
Lynch, P; Ohshima, M; Riggs, C; Ward, JM1
Schuller, HM; Ward, JM1
Chojnacki, T; Dallner, G; Edlund, C1
Creasia, D; Lynch, P; Rice, JM; Riggs, C; Ward, JM1
Carls, N; Schiestl, RH1
Knights, KM; Roberts, BJ1
Devor, DE; Henneman, JR; Ward, JM; Weghorst, CM1
Cattley, RC; Glover, SE1
Gunz, D; Lutz, WK; Shephard, SE1
Fung, KY; Krewski, D; Lutz, WK; Shephard, S; Zhu, Y1
Mock, DM; Mock, NI; Wang, KS1
Goodman, JI1
Ackley, DC; Isenberg, JS; Kamendulis, LM; Klaunig, JE; Lington, AW; McKee, RH; Pugh, G; Smith, JH1
Goyak, KM; Johnson, MC; Omiecinski, CJ; Strom, SC1
Aleksunes, LM; Corton, JC; George, MH; Klaassen, CD; Ren, H; Vallanat, B; Wood, C1
Abounassif, M; Al-Majed, A; Alrabiah, H; Mostafa, GA1
Abe, J; Kimura, K; Maeda, M; Ogata, K; Utsumi, T; Yamaguchi, T1

Reviews

2 review(s) available for phenobarbital and diethylhexyl phthalate

ArticleYear
Statistical analysis of the lacI transgenic mouse mutagenicity assay.
    Mutation research, 1997, Mar-04, Volume: 374, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Bacterial Proteins; Computer Simulation; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Escherichia coli Proteins; Heptachlor; Lac Repressors; Liver; Mice; Mice, Transgenic; Models, Genetic; Mutagenicity Tests; Phenobarbital; Repressor Proteins; Urinary Bladder

1997
Characterization of peroxisome proliferator-activated receptor alpha--independent effects of PPARalpha activators in the rodent liver: di-(2-ethylhexyl) phthalate also activates the constitutive-activated receptor.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 113, Issue:1

    Topics: Animals; Clofibrate; Constitutive Androstane Receptor; Diethylhexyl Phthalate; Gene Expression Profiling; Gene Expression Regulation; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligonucleotide Array Sequence Analysis; Peroxisome Proliferators; Phenobarbital; Plasticizers; PPAR alpha; Pregnane X Receptor; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription, Genetic; Valproic Acid

2010

Other Studies

26 other study(ies) available for phenobarbital and diethylhexyl phthalate

ArticleYear
Effects of modifying agents on conformity of enzyme phenotype and proliferative potential in focal preneoplastic and neoplastic liver cell lesions in rats.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:11

    Topics: Adenosine Triphosphatases; Animals; Bromodeoxyuridine; Cell Division; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Ethoxyquin; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutathione Transferase; Isoenzymes; Liver Neoplasms, Experimental; Male; Phenobarbital; Phenotype; Precancerous Conditions; Rats; Rats, Inbred F344; Tumor Cells, Cultured

1992
Quantitative image cytometry of hepatocytes expressing gamma-glutamyl transpeptidase and glutathione S-transferase in diethylnitrosamine-initiated rats treated with phenobarbital and/or phthalate esters.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1992, Volume: 40, Issue:8

    Topics: Animals; Biomarkers, Tumor; Carcinogens; Diethylhexyl Phthalate; Diethylnitrosamine; gamma-Glutamyltransferase; Glutathione Transferase; Histocytochemistry; Image Processing, Computer-Assisted; Immunoenzyme Techniques; Liver; Male; Phenobarbital; Phthalic Acids; Rats; Rats, Inbred F344

1992
Microsomal lauric acid hydroxylase activities after treatment of rats with three classical cytochrome P450 inducers and peroxisome proliferating compounds.
    Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12

    Topics: Adipates; Animals; Aroclors; Body Weight; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Enzyme Induction; Male; Methylcholanthrene; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Nafenopin; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains

1992
Effects of the peroxisome proliferator di(2-ethylhexyl)phthalate on enzymes in rat liver and on carcinogen-induced liver altered foci in comparison to the promoter phenobarbital.
    Toxicologic pathology, 1990, Volume: 18, Issue:2

    Topics: 2-Acetylaminofluorene; Adenosine Triphosphate; Alkaline Phosphatase; Animals; Cell Transformation, Neoplastic; Diethylhexyl Phthalate; gamma-Glutamyltransferase; Glucose-6-Phosphatase; Histocytochemistry; Liver; Liver Neoplasms; Male; Microbodies; Phenobarbital; Phthalic Acids; Rats; Rats, Inbred F344

1990
The effects of inducers of the endoplasmic reticulum, peroxisomes and mitochondria on the amounts and synthesis of ubiquinone in rat liver subcellular membranes.
    Chemico-biological interactions, 1990, Volume: 73, Issue:2-3

    Topics: Animals; Cholesterol, Dietary; Cholestyramine Resin; Chromatography, High Pressure Liquid; Clofibrate; Diethylhexyl Phthalate; Diethylnitrosamine; Dolichols; Endoplasmic Reticulum; Intracellular Membranes; Liver; Methylcholanthrene; Mevalonic Acid; Microbodies; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Ubiquinone

1990
Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters.
    Carcinogenesis, 1987, Volume: 8, Issue:10

    Topics: Adipates; Aflatoxin B1; Aflatoxins; Aldrin; Animals; Benzidines; Biological Availability; Carbon Tetrachloride; Carcinogens; Cell Division; Circadian Rhythm; DDT; Diethylhexyl Phthalate; DNA; DNA Replication; Female; Hexachlorocyclohexane; Isomerism; Liver; Liver Neoplasms; Male; Mice; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Thioacetamide

1987
Induction of hepatic metallothionein in male B6C3F1 mice exposed to hepatic tumor promoters: effects of phenobarbital, acetaminophen, sodium barbital, and di(2-ethylhexyl) phthalate.
    Toxicology and applied pharmacology, 1989, Sep-01, Volume: 100, Issue:2

    Topics: Acetaminophen; Animals; Barbital; Cadmium; Carcinogens; Chromatography, Gel; Cytosol; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Liver; Male; Metallothionein; Mice; Phenobarbital; Phthalic Acids; Zinc

1989
Phosphorylation of specific rat plasma membrane proteins during promotion of gamma-glutamyl transpeptidase-positive hepatic foci and inhibition by di(2-ethylhexyl)phthalate.
    Cancer research, 1985, Volume: 45, Issue:6

    Topics: Animals; Chlorine; Diethylhexyl Phthalate; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Membrane Proteins; Molecular Weight; Phenobarbital; Phosphorylation; Phthalic Acids; Precancerous Conditions; Prohibitins; Protein Kinases; Rats; Rats, Inbred Strains

1985
The chronic hepatic or renal toxicity of di(2-ethylhexyl) phthalate, acetaminophen, sodium barbital, and phenobarbital in male B6C3F1 mice: autoradiographic, immunohistochemical, and biochemical evidence for levels of DNA synthesis not associated with car
    Toxicology and applied pharmacology, 1988, Volume: 96, Issue:3

    Topics: Acetaminophen; Animals; Autoradiography; Barbital; Barbiturates; Diethylhexyl Phthalate; DNA; Immunohistochemistry; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Phenobarbital; Phthalic Acids; Thymidine Kinase

1988
Tumor-initiating and promoting activities of di(2-ethylhexyl) phthalate in vivo and in vitro.
    Environmental health perspectives, 1986, Volume: 65

    Topics: Adenoma; Animals; Carcinogens; Carcinoma; Cell Transformation, Neoplastic; Cells, Cultured; Diethylhexyl Phthalate; Diethylnitrosamine; Female; Liver Neoplasms, Experimental; Male; Mice; Phenobarbital; Phthalic Acids; Plasticizers; Rats; Skin Neoplasms

1986
Inhibition of phenobarbital and dietary choline deficiency promoted preneoplastic lesions in rat liver by environmental contaminant di(2-ethylhexyl)phthalate.
    Cancer letters, 1984, Volume: 23, Issue:3

    Topics: Animals; Choline Deficiency; Diet; Diethylhexyl Phthalate; gamma-Glutamyltransferase; Liver Neoplasms; Male; Phenobarbital; Phthalic Acids; Precancerous Conditions; Prohibitins; Rats; Rats, Inbred Strains

1984
Di(2-ethylhexyl)phthalate but not phenobarbital promotes N-nitrosodiethylamine-initiated hepatocellular proliferative lesions after short-term exposure in male B6C3F1 mice.
    Cancer letters, 1984, Volume: 24, Issue:1

    Topics: Animals; Cocarcinogenesis; Diethylhexyl Phthalate; Diethylnitrosamine; Liver; Liver Neoplasms; Lung; Male; Mice; Mice, Inbred Strains; Phenobarbital; Phthalic Acids

1984
Quantitative electron microscopic analysis of changes in peroxisomes and endoplasmic reticulum induced in mice during hepatocarcinogenesis by diethylnitrosamine promoted by di(2-ethylhexyl)phthalate or phenobarbital.
    Journal of experimental pathology, 1984,Fall, Volume: 1, Issue:4

    Topics: Animals; Diethylhexyl Phthalate; Diethylnitrosamine; Endoplasmic Reticulum; Liver Neoplasms, Experimental; Male; Mice; Microbodies; Microscopy, Electron; Mitochondria, Liver; Phenobarbital; Phthalic Acids

1984
Separation of dolichol and dolichyl-P in microsomal and lysosomal compartments of hepatocytes.
    Biochemical and biophysical research communications, 1983, Sep-30, Volume: 115, Issue:3

    Topics: Animals; Diethylhexyl Phthalate; Diethylnitrosamine; Diterpenes; Dolichol Phosphates; Dolichols; Kinetics; Liver; Lysosomes; Male; Microsomes, Liver; Phenobarbital; Polyisoprenyl Phosphates; Rats; Rats, Inbred Strains

1983
Dissimilar patterns of promotion by di(2-ethylhexyl)phthalate and phenobarbital of hepatocellular neoplasia initiated by diethylnitrosamine in B6C3F1 mice.
    Carcinogenesis, 1983, Volume: 4, Issue:8

    Topics: Adenoma; Animals; Carcinogens; Diethylhexyl Phthalate; Diethylnitrosamine; Drug Synergism; Hyperplasia; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Phthalic Acids

1983
Evaluation of the yeast DEL assay with 10 compounds selected by the International Program on Chemical Safety for the evaluation of short-term tests for carcinogens.
    Mutation research, 1994, Volume: 320, Issue:4

    Topics: Acrylonitrile; Benzene; Carcinogens; Chromosome Deletion; Diethylhexyl Phthalate; Diethylstilbestrol; Hempa; Mutagenicity Tests; Phenobarbital; Saccharomyces cerevisiae; Safrole; Toluidines

1994
Differential induction of rat hepatic microsomal and peroxisomal long-chain and nafenopin-CoA ligases by clofibric acid and di-(2-ethylhexyl)phthalate.
    Xenobiotica; the fate of foreign compounds in biological systems, 1995, Volume: 25, Issue:5

    Topics: Acyl Coenzyme A; Animals; Clofibric Acid; Coenzyme A Ligases; Diethylhexyl Phthalate; In Vitro Techniques; Male; Microbodies; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Repressor Proteins; Saccharomyces cerevisiae Proteins

1995
Promotion of hepatocellular foci and adenomas by di(2-ethylhexyl) phthalate and phenobarbital in C3H/HeNCr mice following exposure to N-nitrosodiethylamine at 15 days of age.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 45, Issue:7

    Topics: Adenoma, Liver Cell; Animals; Diethylhexyl Phthalate; Diethylnitrosamine; Disease Models, Animal; Female; Incidence; Liver Neoplasms; Male; Mice; Mice, Inbred C3H; Phenobarbital

1994
Elevated 8-hydroxydeoxyguanosine in hepatic DNA of rats following exposure to peroxisome proliferators: relationship to carcinogenesis and nuclear localization.
    Carcinogenesis, 1993, Volume: 14, Issue:12

    Topics: Animals; Body Weight; Carcinogens; Cell Nucleus; Clofibric Acid; Diethylhexyl Phthalate; DNA; Guanosine; Liver; Male; Microbodies; Organ Size; Phenobarbital; Pyrimidines; Rats; Rats, Inbred F344

1993
Can nongenotoxic carcinogens be detected with the lacI transgenic mouse mutation assay?
    Environmental and molecular mutagenesis, 1993, Volume: 21, Issue:3

    Topics: Animals; beta-Galactosidase; Carcinogens; Diethylhexyl Phthalate; Female; Genes, Regulator; Genetic Markers; Heptachlor; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Mutagenicity Tests; Phenobarbital

1993
Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats.
    The Journal of nutrition, 1997, Volume: 127, Issue:11

    Topics: Analysis of Variance; Animals; Anticonvulsants; Biotin; Biotransformation; Carbamazepine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Clofibrate; Dehydroepiandrosterone; Dexamethasone; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Male; Microbodies; Phenobarbital; Phenytoin; Radiometry; Rats; Rats, Sprague-Dawley; Steroids

1997
Operational reversibility is a key aspect of carcinogenesis.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 64, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Diethylhexyl Phthalate; Gap Junctions; Humans; Liver; Mice; Phenobarbital

2001
Reversibility and persistence of di-2-ethylhexyl phthalate (DEHP)- and phenobarbital-induced hepatocellular changes in rodents.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 64, Issue:2

    Topics: Animals; Body Weight; Cell Communication; Cell Transformation, Neoplastic; Diet; Diethylhexyl Phthalate; DNA Replication; Fatty Acids; Gap Junctions; Liver; Male; Mice; Mice, Inbred Strains; Oxidation-Reduction; Peroxisomes; Phenobarbital; Phthalic Acids; Rats; Rats, Inbred F344

2001
Expression profiling of interindividual variability following xenobiotic exposures in primary human hepatocyte cultures.
    Toxicology and applied pharmacology, 2008, Sep-01, Volume: 231, Issue:2

    Topics: Cells, Cultured; Chlorodiphenyl (54% Chlorine); Diethylhexyl Phthalate; Gene Expression Profiling; Gene Expression Regulation; Genome, Human; Hepatocytes; Humans; Phenobarbital; Reproducibility of Results; Xenobiotics

2008
Ionophore-based potentiometric PVC membrane sensors for determination of phenobarbitone in pharmaceutical formulations.
    Acta pharmaceutica (Zagreb, Croatia), 2016, Dec-01, Volume: 66, Issue:4

    Topics: Anticonvulsants; beta-Cyclodextrins; Biosensing Techniques; Calibration; Chemistry, Pharmaceutical; Diethylhexyl Phthalate; gamma-Cyclodextrins; Hydrogen-Ion Concentration; Indicators and Reagents; Ionophores; Limit of Detection; Membrane Potentials; Membranes, Artificial; Pharmaceutical Solutions; Phenobarbital; Plasticizers; Polyvinyl Chloride; Quaternary Ammonium Compounds; Reproducibility of Results; Tablets

2016
The effects on the endocrine system under hepatotoxicity induction by phenobarbital and di(2-ethylhexyl)phthalate in intact juvenile male rats.
    The Journal of toxicological sciences, 2019, Volume: 44, Issue:7

    Topics: Animals; Animals, Newborn; Anticonvulsants; Cytochrome P-450 Enzyme System; Diethylhexyl Phthalate; Endocrine System; Glucuronosyltransferase; Liver; Male; Phenobarbital; Plasticizers; Rats, Sprague-Dawley; Testosterone; Thyroid Gland; Time Factors

2019