phenobarbital has been researched along with diethyl maleate in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (78.57) | 18.7374 |
| 1990's | 6 (21.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hermanson, R; Högberg, J; Moldéus, P; Orrenius, S; Reed, DJ; Thor, J | 1 |
| Gullberg, D; Högberg, J; Rubin, K; Stenius, U | 1 |
| Giri, SN; Siegel, DM | 1 |
| Braide, SA | 1 |
| Dalich, GM; Larson, RE | 1 |
| Hirose, M; Inoue, T; Ito, N; Masuda, A; Tsuda, H | 1 |
| Farber, JL; Kyle, ME; Nakae, D; Serroni, A | 1 |
| DeAngelo, AB; Guion, C; Pereira, MA; Savage, RE | 1 |
| Flory, W; Henk, WG; Turk, MA | 1 |
| Brandt, I; Klasson-Wehler, E; Lund, BO | 1 |
| Bianco, MT; Di Simplicio, P; Naldini, A | 1 |
| Gillette, JR; Greene, KE; Lau, SS; Monks, TJ | 1 |
| Anundi, I; Dawson, JR; Moldéus, P; Norbeck, K | 1 |
| Buckpitt, AR; Pong, RS; Whyte, WL | 1 |
| Chakrabarti, S; Law, FC | 1 |
| Elovaara, E; Heinonen, T; Legraverend, C; Uusvuori, R; Zitting, A | 1 |
| Clark, JD; Hatch, RC; Jain, AV; Weiss, R | 2 |
| Egashira, T; Kuroiwa, Y; Yamamoto, T; Yoshida, T | 1 |
| Bechtold, MM; Bruenner, U; Gee, DL; Tappel, AL | 1 |
| Mackenroth, T; Siegers, CP; Younes, M | 1 |
| Anders, MW; Stevens, JL | 2 |
| Berg, IE; Chaturvedi, AK; Rao, NG | 1 |
| Barros, AR; Comendador, MA; Sierra, LM | 1 |
| Barrenscheen, M; Doehmer, J; Glatt, HR; Goeptar, AR; Groot, EJ; Seidel, A; te Koppele, JM; Vermeulen, NP; Wölfel, C | 1 |
| Dijkstra, M; Havinga, R; Kuipers, F; Smit, EP; Vonk, RJ | 1 |
| Timbrell, JA; Waterfield, CJ | 1 |
28 other study(ies) available for phenobarbital and diethyl maleate
| Article | Year |
|---|---|
Metabolic activation and hepatotoxicity. Toxicity of bromobenzene in hepatocytes isolated from phenobarbital-and diethylmaleate-treated rats.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Biotransformation; Bromobenzenes; Coenzyme A; Female; Glutathione; Kinetics; Liver; Male; Maleates; NAD; Phenobarbital; Rats | 1978 |
gamma-Glutamyltranspeptidase-positive rat hepatocytes are protected from GSH depletion, oxidative stress and reversible alterations of collagen receptors.
Topics: Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cells, Cultured; Collagen; Diethylnitrosamine; Diquat; Female; gamma-Glutamyltransferase; Glutathione; Hydrogen Peroxide; Hydroquinones; Ketones; Kinetics; Liver; Maleates; Phenobarbital; Rats; Receptors, Cell Surface; Receptors, Collagen; Selenium; Sodium Selenite; Vitamin K | 1990 |
Role of mixed-function oxidases and non-protein sulfhydryl content in [14C]-2-chloro-4-acetotoluidide binding to liver and kidney in starlings.
Topics: Animals; Birds; Carbon Radioisotopes; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glutathione; Kidney; Liver; Male; Maleates; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Pyridines; Sulfhydryl Compounds; Toluidines | 1990 |
A requirement for low concentration of hepatic glutathione for induction of gammaglutamyltransferase by phenobarbitone.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Induction; gamma-Glutamyltransferase; Glutathione; Kinetics; Liver; Male; Maleates; Phenobarbital; Rats; Rats, Inbred Strains | 1989 |
A comparative study of the hepatotoxicity of monochlorobenzene in the rainbow trout (Salmo gairdnerii) and the Sprague-Dawley rat.
Topics: Alanine Transaminase; Animals; Benzoflavones; beta-Naphthoflavone; Chlorobenzenes; Glutathione; Liver; Male; Maleates; Necrosis; Neurons; Phenobarbital; Protein Binding; Rats; Rats, Inbred Strains; Salmonidae; Species Specificity; Time Factors; Trout | 1985 |
Effects of simultaneous treatment with various chemicals on BHA-induced development of rat forestomach hyperplasia--complete inhibition by diethylmaleate in a 5-week feeding study.
Topics: Aminocaproic Acid; Animals; Body Weight; Butylated Hydroxyanisole; Dexamethasone; Diet; Diterpenes; Drug Interactions; Eating; Indomethacin; Liver; Male; Maleates; Organ Size; Phenobarbital; Polychlorinated Biphenyls; Rats; Rats, Inbred F344; Retinyl Esters; Stomach; Vitamin A | 1987 |
1,3-(2-Chloroethyl)-1-nitrosourea potentiates the toxicity of acetaminophen both in the phenobarbital-induced rat and in hepatocytes cultured from such animals.
Topics: Acetaminophen; Acetone; Carmustine; Cell Survival; Deferoxamine; Drug Synergism; Enzyme Induction; Glutathione; Liver; Male; Maleates; Methylcholanthrene; Phenobarbital; Phenylenediamines | 1988 |
Studies on the mechanism of action of chloroform stimulation of rat hepatic ornithine decarboxylase (ODC).
Topics: Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Chloroform; Cytosol; Female; Indomethacin; Injections, Intravenous; Liver; Male; Maleates; Ornithine Decarboxylase; Phenobarbital; Propranolol; Rats; Rats, Inbred F344; Reserpine; Stimulation, Chemical | 1987 |
Chemical modulation of 3-methylindole toxicosis in mice: effect on bronchiolar and olfactory mucosal injury.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bronchi; Epithelium; Female; Flavonoids; Glutathione; Indoles; Male; Maleates; Mice; Mice, Inbred C57BL; Mixed Function Oxygenases; Nasal Mucosa; Phenobarbital; Piperonyl Butoxide; Proadifen; Sex Factors; Skatole | 1986 |
o,p'-DDD in the mouse lung: selective uptake, covalent binding and effect on drug metabolism.
Topics: Adipose Tissue; Adrenal Glands; Aminopyrine; Animals; Autoradiography; Benzoflavones; beta-Naphthoflavone; DDT; Dose-Response Relationship, Drug; Isomerism; Liver; Lung; Maleates; Metyrapone; Mice; Mice, Inbred C57BL; Mitotane; Phenobarbital; Pulmonary Alveoli | 1986 |
[Relation between glutathione and cytoplasmic protein sulfhydryl groups in the rat: a rapid procedure for analytical determination].
Topics: Animals; Carbon Tetrachloride Poisoning; Cytoskeletal Proteins; Glutathione; Hydrocarbons, Iodinated; Liver; Maleates; Methods; Phenobarbital; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1984 |
Detection and half-life of bromobenzene-3,4-oxide in blood.
Topics: Animals; Bromobenzenes; Half-Life; Male; Maleates; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
The effectiveness of N-acetylcysteine in isolated hepatocytes, against the toxicity of paracetamol, acrolein, and paraquat.
Topics: Acetaminophen; Acetone; Acetylcysteine; Acrolein; Aldehydes; Amino Acids; Animals; Cell Survival; Chemical and Drug Induced Liver Injury; Glutathione; Liver; Male; Maleates; Paraquat; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Glutathione and glutathione S-transferases in the urinary bladder of different species.
Topics: Animals; Aroclors; Chlorodiphenyl (54% Chlorine); Cricetinae; Female; Glutathione; Glutathione Transferase; Guinea Pigs; Humans; In Vitro Techniques; Liver; Maleates; Phenobarbital; Rabbits; Rats; Species Specificity; Urinary Bladder | 1984 |
Effects of drug and chemical pretreatments on biliary excretion of phenylcyclohexene in the rat.
Topics: Animals; Bile; Cyclohexanes; Enzyme Induction; Glutathione; Kinetics; Male; Maleates; Methylcholanthrene; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Inbred Strains; Time Factors | 1984 |
DNA binding of [14C]styrene in isolated rat hepatocytes.
Topics: Animals; Carbon Radioisotopes; Cattle; DNA; In Vitro Techniques; Kinetics; Liver; Magnetic Resonance Spectroscopy; Male; Maleates; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Styrene; Styrenes; Thymus Gland | 1984 |
Effect of enzyme inducers and inhibitors and glutathione precursor and depleter on induced acute aflatoxicosis in rabbits.
Topics: Acute Disease; Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; Carcinogens; Chlorides; Cobalt; Cysteine; Enzyme Induction; Enzyme Inhibitors; Glutathione; Goats; Liver; Male; Maleates; Microsomes, Liver; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Rabbits; Rats; Stanozolol | 1982 |
Effect of adrenalectomy, pretreatment with SKF 525-A, phenobarbital and diethyl maleate on the acute toxicity of fenitrothion in male rats.
Topics: Adrenalectomy; Animals; Cholinesterases; Fenitrothion; Glutathione; In Vitro Techniques; Male; Maleates; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1983 |
Carbon tetrachloride-mediated expiration of pentane and chloroform by the intact rat: the effects of pretreatment with diethyl maleate, SKF-525A and phenobarbital.
Topics: Animals; Carbon Tetrachloride; Chloroform; Drug Interactions; Glutathione; Lipid Peroxides; Male; Maleates; Pentanes; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1982 |
Toxicologic study of carboxyatractyloside (active principle in cocklebur--Xanthium strumarium) in rats treated with enzyme inducers and inhibitors and glutathione precursor and depletor.
Topics: Animals; Atractyloside; Benzoflavones; beta-Naphthoflavone; Cobalt; Cysteine; Glycosides; Kidney Tubules; Lethal Dose 50; Liver; Male; Maleates; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Plants, Toxic; Rats; Rats, Inbred Strains; Stanozolol | 1982 |
[Inhibition and acceleration of the metabolism of enflurane and methoxyflurane in rats (author's transl)].
Topics: Animals; DDT; Dimethyl Sulfoxide; Drug Interactions; Enflurane; Ethanol; Half-Life; Male; Maleates; Methoxyflurane; Phenobarbital; Rats; Rifampin | 1981 |
Effect of cysteine, diethyl maleate, and phenobarbital treatments on the hepatotoxicity of [1H]chloroform.
Topics: Alanine Transaminase; Animals; Biotransformation; Chloroform; Cysteine; Liver; Male; Maleates; Phenobarbital; Phosgene; Rats; Rats, Inbred Strains | 1981 |
Metabolism of haloforms to carbon monoxide. IV. studies on the reaction mechanism in vivo.
Topics: Animals; Carbon Monoxide; Carcinogens; Chloroform; Cysteine; Deuterium; Hydrocarbons, Brominated; Male; Maleates; Phenobarbital; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines; Trihalomethanes | 1981 |
The role of hepatic microsomal enzymes in the modulation of phencyclidine-induced toxicity.
Topics: Animals; Body Weight; Cysteine; Eating; Lethal Dose 50; Liver; Male; Maleates; Methylcholanthrene; Mice; Microsomes, Liver; Pentobarbital; Phencyclidine; Phenobarbital; Proadifen | 1981 |
Acrolein genotoxicity in Drosophila melanogaster. III. Effects of metabolism modification.
Topics: Acrolein; Animals; Biotransformation; Cytochrome P-450 Enzyme Inhibitors; Drosophila melanogaster; Female; Glutathione; Imidazoles; Iproniazid; Male; Maleates; Mutagenicity Tests; Mutation; Phenobarbital | 1994 |
The cytotoxicity of mitomycin C and adriamycin in genetically engineered V79 cell lines and freshly isolated rat hepatocytes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cell Death; Cells, Cultured; Cricetinae; Cricetulus; Cyclophosphamide; Cytochrome P-450 Enzyme System; Dihydroxydihydrobenzopyrenes; Doxorubicin; Enzyme Induction; Enzyme Inhibitors; Fibroblasts; L-Lactate Dehydrogenase; Liver; Male; Maleates; Metyrapone; Mitomycin; Phenobarbital; Rats; Rats, Wistar; Transfection | 1995 |
The role of glutathione in bile secretion of endogenous trace elements in rats.
Topics: Animals; Bile; Bromine; Calcium; Copper; Ethanol; Glutathione; Iron; Liver; Male; Maleates; Manganese; Molybdenum; Phenobarbital; Potassium; Rats; Rats, Wistar; Regression Analysis; Spectrometry, X-Ray Emission; Zinc | 1993 |
Changes in taurine as an indicator of hepatic dysfunction and biochemical perturbations. Studies in vivo and in vitro.
Topics: Animals; Biomarkers; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cells, Cultured; Clenbuterol; Galactosamine; Glutathione; Ketones; Liver; Liver Diseases; Male; Maleates; Necrosis; Phenobarbital; Rats; Rats, Sprague-Dawley; Taurine; Thioacetamide | 1996 |