phenobarbital and dicumarol

phenobarbital has been researched along with dicumarol in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (90.48)	18.7374
1990's	3 (7.14)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (2.38)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Edds, GT; Himes, JA; Silvestri, R	1
Berman, ML	1
Kutt, H	2
Darnis, F	1
Lai, CM; Levy, G; Yacobi, A	1
Levy, G; Slattery, JT; Yacobi, A	1
Eisenbrandt, LL; Husain, S; Wosilait, WD	1
Livingston, S; Pauli, LL; Pruce, I	1
Crow, JW; Gibaldi, M; Levy, G	2
Mehendale, HM; Utley, WS	1
Amanuma, T; Denda, A; Kurokawa, Y; Maruyama, H; Murata, Y; Nakae, D; Sai, KM; Tang, Q; Tsujiuchi, T; Tsutsumi, M	1
Greim, H	1
Kato, R; Oshima, T; Takahashi, A	1
Dean, RR; Karim, A; Radzialowski, FM; Ranney, RE	1
Greene, FE; Page, JG; Passananti, GT; Vesell, ES	1
Passananti, GT; Vessell, ES	1
Browne, R; Possley, L; Zaroslinski, J	1
Edds, GT; Himes, JA; Shetty, SN	2
La Du, BN	1
Christensen, F	1
Jatlow, P	1
Welch, RM	1
Kutt, H; Penry, JK	1
Dickhaus, DW; Goss, JE	1
Corn, M; Rockett, JF	1
Burns, JJ; Conney, AH	2
Christensen, LK; Hansen, JM; Kristensen, M; Skovsted, L	1
Cucinell, SA; Dayton, PG; Odessky, L; Weiss, M	1
Cucinell, SA; Dayton, PG; Perel, JM; Weiss, M	1
Martin, YC	1
Estabrook, RW; Greim, H; Remmer, H; Schenkman, J	1
Conney, AH	1
Burns, JJ	2
Hom, FS; Miskel, JJ	1
Grant, MH; Li, SJ; Rodgers, EH	1
BURNS, JJ; CONNEY, AH; CUCINELL, SA; KOSTER, R	1

Reviews

6 review(s) available for phenobarbital and dicumarol

Article	Year
Biochemical and genetic factors regulating dilantin metabolism in man. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Aminosalicylic Acids; Animals; Ataxia; Cats; Chlordan; Cycloserine; DDT; Dicumarol; Disulfiram; Enzyme Induction; Female; Genetics, Medical; Humans; Intestinal Absorption; Isoniazid; Kinetics; Liver Diseases; Male; Metabolism; Microsomes, Liver; Nystagmus, Pathologic; Pedigree; Pharmacogenetics; Phenobarbital; Phenytoin; Rats; Thiazines	1971
Utility of clinical chemical determinations of drug concentrations in biological fluids. Clinical chemistry, 1971, Volume: 17, Issue:9 Topics: Adult; Allopurinol; Antipyrine; Ataxia; Chemistry, Clinical; Chromatography, Gas; Coffee; Desipramine; Dicumarol; Drug Antagonism; Drug Synergism; Ethanol; Female; Fluorometry; Half-Life; Humans; Iatrogenic Disease; Male; Mental Disorders; Metabolism; Methods; Middle Aged; Morphine; Nortriptyline; Nystagmus, Pathologic; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Pregnancy; Smoking; Spectrophotometry; Twins; Ultraviolet Rays	1971
Pharmacogenetics: defective enzymes in relation to reactions to drugs. Annual review of medicine, 1972, Volume: 23 Topics: Acetylation; Cholinesterases; Coumarins; Dicumarol; Dose-Response Relationship, Drug; Female; Genetic Code; Genetic Diseases, Inborn; Glucosephosphate Dehydrogenase Deficiency; Humans; Isoniazid; Male; Metabolism, Inborn Errors; Pharmacogenetics; Phenacetin; Phenobarbital; Phenytoin; Succinylcholine	1972
Usefulness of blood levels of antiepileptic drugs. Archives of neurology, 1974, Volume: 31, Issue:5 Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines	1974
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY. The American journal of medicine, 1964, Volume: 37 Topics: Animals; Benzopyrenes; Cyclizine; Dicumarol; Diphenhydramine; Dogs; Drug Therapy; Enzyme Induction; Enzymes; Glutethimide; Hexobarbital; Liver; Meprobamate; Metabolism; Pharmacology; Phenobarbital; Phenylbutazone; Phenytoin; Probenecid; Rats; Research; Tolbutamide; Toxicology; Zoxazolamine	1964
THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM. Seminars in hematology, 1964, Volume: 1 Topics: Aminopyrine; Chloramphenicol; Coumarins; Dicumarol; Humans; Metabolism; Pharmaceutical Preparations; Pharmacology; Phenacetin; Phenobarbital; Phenylbutazone	1964

Trials

1 trial(s) available for phenobarbital and dicumarol

Article	Year
Increased bishydroxycoumarin requirements in patients receiving phenobarbital. The New England journal of medicine, 1965, Nov-11, Volume: 273, Issue:20 Topics: Adult; Aged; Blood Coagulation Tests; Clinical Trials as Topic; Coronary Disease; Dicumarol; Humans; Male; Middle Aged; Phenobarbital	1965

Other Studies

35 other study(ies) available for phenobarbital and dicumarol

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Repeated oral administration of coumaphos in sheep: interactions of coumaphos with bishydroxycoumarin, trichlorfon, and phenobarbital sodium. American journal of veterinary research, 1975, Volume: 36, Issue:3 Topics: Acetylcholinesterase; Administration, Oral; Animals; Cholinesterase Inhibitors; Coumaphos; Dicumarol; Drug Interactions; Erythrocytes; Female; Injections, Intraperitoneal; Injections, Intravenous; Insecticides; Phenobarbital; Prothrombin Time; Sheep; Sheep Diseases; Trichlorfon	1975
Significance of enzyme induction to clinical anesthesia. Clinical anesthesia, 1975, Volume: 11, Issue:1 Topics: Anesthetics; Animals; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Dicumarol; Enzyme Induction; Humans; Kidney; Liver; Microsomes; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Phenobarbital	1975
Interactions of antiepileptic drugs. Epilepsia, 1975, Volume: 16, Issue:2 Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines	1975
[Liver metabolism of drugs (author's transl)]. MMW, Munchener medizinische Wochenschrift, 1976, Jun-18, Volume: 118, Issue:25 Topics: Adult; Animals; Anticonvulsants; Biotransformation; Calcium; Child; Cushing Syndrome; Dicumarol; Drug Synergism; Enzyme Induction; Humans; Infant, Newborn; Jaundice; Kinetics; Liver; Microsomes, Liver; Mitochondria, Liver; Pharmaceutical Preparations; Phenobarbital; Phenylbutazone; Phosphorus; Porphyrias; Protein Binding; Species Specificity; Vitamin D	1976
Relationship between dicumarol distribution and the effect of enzyme induction on dicumarol elimination in rats. The Journal of pharmacology and experimental therapeutics, 1976, Volume: 199, Issue:1 Topics: Animals; Dicumarol; Enzyme Induction; Kidney; Kinetics; Liver; Male; Phenobarbital; Rats	1976
Comparative pharmacokinetics of coumarin anticoagulants XXIV: Effect of treatment with phenobarbital on serum protein binding of warfarin and dicumarol in rats. Journal of pharmaceutical sciences, 1977, Volume: 66, Issue:7 Topics: Animals; Blood Proteins; Dicumarol; Kinetics; Male; Phenobarbital; Protein Binding; Rats; Warfarin	1977
Excretion of 14C-dicumarol or its metabolites in the bile of rats during choleresis. Proceedings of the Western Pharmacology Society, 1978, Volume: 21 Topics: Animals; Bile; Cholagogues and Choleretics; Cholic Acids; Dicumarol; Female; Phenobarbital; Rats	1978
The medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity. Pediatric annals, 1979, Volume: 8, Issue:4 Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Carbamazepine; Child; Dicumarol; Digitoxin; Drug Interactions; Female; Humans; Male; Oxacillin; Phenobarbital; Phenytoin; Pregnancy; Vitamin D	1979
Comparative pharmacokinetics of coumarin anticoaglulants XLI: Effect of phenobarbital on systemic availability of orally administered dicumarol in rats. Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:8 Topics: Administration, Oral; Animals; Biological Availability; Dicumarol; Drug Interactions; Kinetics; Male; Phenobarbital; Rats	1979
Comparative pharmacokinetics of coumarin anticoagulants. XLII: Effect of phenobarbital on systemic availability of orally administered dicumarol in rats with ligated bile ducts. Journal of pharmaceutical sciences, 1979, Volume: 68, Issue:10 Topics: Animals; Bile Ducts; Biological Availability; Dicumarol; Drug Interactions; Gastrointestinal Motility; Intestinal Absorption; Kinetics; Male; Phenobarbital; Rats; Time Factors	1979
Phenobarbital-induced cytoprotective mechanisms in menadione metabolism: the role of glutathione reductase and DT-diaphorase. The International journal of biochemistry, 1990, Volume: 22, Issue:9 Topics: Animals; Carmustine; Cell Survival; Dicumarol; Drug Interactions; Glutathione Reductase; Kinetics; Liver; Male; NAD(P)H Dehydrogenase (Quinone); Phenobarbital; Quinone Reductases; Rats; Rats, Inbred Strains; Superoxides; Vitamin K	1990
Induction of 8-hydroxydeoxyguanosine but not initiation of carcinogenesis by redox enzyme modulations with or without menadione in rat liver. Carcinogenesis, 1991, Volume: 12, Issue:4 Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Body Weight; Cytochrome Reductases; Deoxyguanosine; Dicumarol; DNA; DNA Damage; gamma-Glutamyltransferase; Glutathione; Iron; Ketones; Liver; Liver Neoplasms, Experimental; Male; NAD(P)H Dehydrogenase (Quinone); Necrosis; Neoplasms, Experimental; Organ Size; Oxidation-Reduction; Phenobarbital; Quinone Reductases; Rats; Rats, Inbred F344; Time Factors; Vitamin K	1991
[Therapeutic possibilities using the induction of drug reducing enzymes]. Deutsche medizinische Wochenschrift (1946), 1970, Oct-23, Volume: 95, Issue:43 Topics: Animals; Dicumarol; Electron Transport Complex IV; Enzyme Induction; Enzyme Therapy; Extracellular Space; Histocytochemistry; Humans; Hyperbilirubinemia; Liver; Metabolic Diseases; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; Pharmaceutical Preparations; Phenobarbital; Plasma	1970
Characteristics of nitro reduction of the carcinogenic agent, 4-nitroINOLONE N-oxide. Biochemical pharmacology, 1970, Volume: 19, Issue:1 Topics: Alcohol Oxidoreductases; Animals; Benzoates; Carcinogens; Dicumarol; Flavin Mononucleotide; In Vitro Techniques; Liver; Male; Methylcholanthrene; Microsomes, Liver; NADP; Nitrobenzenes; Oxidation-Reduction; Oxides; Oxidoreductases; Oxygen; Phenobarbital; Quinolines; Rats; Time Factors	1970
Disopyramide phosphate: pharmacokinetic and pharmacologic relationships of a new antiarrhythmic agent. Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 191, Issue:1 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Computers; Dicumarol; Dogs; Electrocardiography; Enzyme Induction; Female; Half-Life; Humans; In Vitro Techniques; Injections, Intravenous; Intestinal Absorption; Kinetics; Male; Methyltransferases; Models, Biological; Muscle Contraction; Phenobarbital; Phosphates; Pyridines; Rats	1971
Genetic control of drug levels and of the induction of drug-metabolizing enzymes in man: individual variability in the extent of allopurinol and nortriptyline inhibition of drug metabolism. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Adult; Allopurinol; Aniline Compounds; Animals; Antipyrine; Coffee; Cytochromes; Dicumarol; Ethanol; Female; Half-Life; Humans; Kinetics; Male; Mathematics; Metabolism; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Morphinans; Nortriptyline; Oxidoreductases; Pharmacogenetics; Phenobarbital; Phenylbutazone; Pregnancy; Rats; Smoking; Statistics as Topic; Tea; Twins; White People	1971
Effect of subacute administration of methaqualone, phenobarbital and glutethimide on plasma levels of bishydroxycoumarin. Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 195, Issue:1 Topics: Administration, Oral; Animals; Depression, Chemical; Dicumarol; Enzyme Induction; Glutethimide; Injections, Intraperitoneal; Male; Methaqualone; Microsomes; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors	1972
Effect of phenobarbital on bishydroxycoumarin plasma concentrations and hypoprothrombinemic responses in sheep. American journal of veterinary research, 1972, Volume: 33, Issue:4 Topics: Administration, Oral; Animals; Dicumarol; Drug Interactions; Female; Hypoprothrombinemias; Injections, Intraperitoneal; Injections, Intravenous; Liver; Microsomes; Phenobarbital; Poisoning; Prothrombin Time; Sheep; Sheep Diseases; Time Factors	1972
Enzyme induction in sheep: effects of phenobarbital on in vivo and in vitro drug metabolism. American journal of veterinary research, 1972, Volume: 33, Issue:5 Topics: Anesthesia; Aniline Compounds; Animals; Antipyrine; Cytochromes; Dicumarol; Enzyme Induction; Female; Formaldehyde; Half-Life; Hexobarbital; Metabolic Clearance Rate; Microsomes, Liver; Pentobarbital; Phenobarbital; Phenols; Proteins; Sheep; Sleep; Sulfobromophthalein; Time Factors	1972
Metabolism of dicoumarol by liver microsomes from untreated and phenobarbital treated rats. Biochemical pharmacology, 1972, Sep-01, Volume: 21, Issue:17 Topics: Animals; Atmosphere; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Dicumarol; Male; Microsomes, Liver; Mitochondria, Liver; NAD; NADP; Phenobarbital; Proteins; Rats; Rats, Inbred Strains; Time Factors	1972
Ultraviolet spectrophotometric analysis of barbiturates: evaluation of potential interferences. American journal of clinical pathology, 1973, Volume: 59, Issue:2 Topics: Acetaminophen; Barbiturates; Chlorothiazide; Chlorpropamide; Dicumarol; Humans; Methods; Nicotinic Acids; Oxyphenbutazone; Phenacetin; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Salicylates; Spectrophotometry, Ultraviolet; Sulfamethoxazole; Sulfinpyrazone; Sulfisoxazole; Theobromine; Theophylline; Warfarin	1973
Drug-protein binding: a method for studying the interactions of drugs with bishydroxycoumarin (dicoumarol) in dogs. Annals of the New York Academy of Sciences, 1973, Nov-26, Volume: 226 Topics: Allopurinol; Animals; Antipyrine; Blood Coagulation; Dicumarol; Dogs; Drug Interactions; Drug Synergism; Enzyme Induction; Half-Life; Liver; Methods; Oxidoreductases; Phenobarbital; Phenylbutazone; Protein Binding; Prothrombin Time; Time Factors; Tolbutamide	1973
Inhibition of bishydroxycoumarin activity by phenobarbital. The Medical annals of the District of Columbia, 1965, Volume: 34, Issue:12 Topics: Adult; Dicumarol; Female; Humans; Male; Phenobarbital; Prothrombin Time	1965
Enzyme stimulation and inhibition in the metabolism of drugs. Proceedings of the Royal Society of Medicine, 1965, Volume: 58, Issue:11 Part 2 Topics: Animals; Dicumarol; Dogs; Enzymes; Liver; Pharmaceutical Preparations; Phenobarbital; Rats	1965
Dicoumarol-induced diphenylhydantoin intoxication. Lancet (London, England), 1966, Jul-30, Volume: 2, Issue:7457 Topics: Blood; Carbon Isotopes; Chromatography, Thin Layer; Dicumarol; Drug Synergism; Humans; Phenobarbital; Phenytoin	1966
The effect of chloral hydrate on bishydroxycoumarin metabolism; a fatal outcome. JAMA, 1966, Aug-01, Volume: 197, Issue:5 Topics: Animals; Chloral Hydrate; Dicumarol; Dogs; Drug Incompatibility; Humans; Male; Middle Aged; Myocardial Infarction; Phenobarbital; Pulmonary Edema	1966
Dose-dependence of drug plasma level decline in dogs. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2 Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K	1967
The effect of ethchlorvynol on the drug-metabolizing enzymes of rats and dogs. Biochemical pharmacology, 1967, Volume: 16, Issue:10 Topics: Aminopyrine; Animals; Dicumarol; Dogs; Ethchlorvynol; Glutethimide; Hypnotics and Sedatives; Liver; Microsomes; NADP; Phenobarbital; Rats	1967
Reaction of drugs with microsomal liver hydroxylase: its influence on drug action. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 259, Issue:2 Topics: Aniline Compounds; Animals; Antipyrine; Benzopyrenes; Cytochromes; Dicumarol; Electron Transport; Enzyme Induction; Hexobarbital; Kinetics; Liver; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Protein Binding; Prothrombin Time	1968
Microsomal enzyme induction by drugs. Pharmacology for physicians, 1969, Volume: 3, Issue:12 Topics: Anticonvulsants; Barbiturates; Bilirubin; Carcinogens; Dicumarol; Enzyme Induction; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Microsomes, Liver; Pharmaceutical Preparations; Phenobarbital; Pregnancy; Prothrombin Time; Steroids	1969
IV. Pharmacogenetics and drug toxicity. Variation of drug metabolism in animals and the prediction of drug action in man. Annals of the New York Academy of Sciences, 1968, Jul-31, Volume: 151, Issue:2 Topics: Animals; Antipyrine; Ascorbic Acid; Barbiturates; Carbon Isotopes; Cats; Chlordan; Dicumarol; Dogs; Environmental Exposure; Ethyl Biscoumacetate; Glucuronates; Guinea Pigs; Haplorhini; Horses; Humans; Meperidine; Oxyphenbutazone; Pharmaceutical Preparations; Phenobarbital; Phenols; Phenylbutazone; Rabbits; Species Specificity; Sulfates	1968
Oral dosage form design and its influence on dissolution rates for a series of drugs. Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:6 Topics: Administration, Oral; Capsules; Dicumarol; Diethylstilbestrol; Digitoxin; Dosage Forms; Drug Compounding; Ethinyl Estradiol; Gastric Juice; Hydrocortisone; Phenobarbital; Phenylbutazone; Propylthiouracil; Reserpine; Solubility; Spectrophotometry; Sulfadiazine; Surface-Active Agents; Tablets; Time Factors; Ultraviolet Rays	1970
The activity of xenobiotic enzymes and the cytotoxicity of mitoxantrone in MCF 7 human breast cancer cells treated with inducing agents. Chemico-biological interactions, 1995, Jul-14, Volume: 97, Issue:2 Topics: Benz(a)Anthracenes; Breast Neoplasms; Cell Death; Cytochrome P-450 Enzyme System; Dexamethasone; Dicumarol; Enzyme Induction; Female; Glutathione; Glutathione Peroxidase; Humans; L-Lactate Dehydrogenase; Metyrapone; Mitoxantrone; NAD(P)H Dehydrogenase (Quinone); NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rifampin; Tumor Cells, Cultured; Xenobiotics	1995
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES. Annals of the New York Academy of Sciences, 1965, Mar-12, Volume: 123 Topics: Aspirin; Blood; Chromatography; Dicumarol; Diphenhydramine; Dogs; Drug-Related Side Effects and Adverse Reactions; Glutethimide; Griseofulvin; Histamine H1 Antagonists; Liver; Meprobamate; Metabolism; Methylcholanthrene; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Piperazines; Probenecid; Rats; Research; Strychnine; Thiopental; Toxicology; Zoxazolamine	1965