phenobarbital and dantrolene

phenobarbital has been researched along with dantrolene in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's1 (10.00)18.2507
2000's1 (10.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Francis, KT; Hamrick, ME1
Abernathy, CO; Ezekiel, M; Utili, R; Zimmerman, HJ1
Batt, AM; Goulon-Ginet, C; Jayyosi, Z; Livertoux, MH; Siest, G; Souhaili, H; Totis, M1
Born, CK; Francis, FT; Hamrick, ME; Roy, S1
Borowicz, KK; Czuczwar, SJ; Gasior, M; Kleinrok, Z1
Lombardo, F; Obach, RS; Waters, NJ1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for phenobarbital and dantrolene

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for phenobarbital and dantrolene

ArticleYear
Dantrolene inhibition of the hepatic mixed function oxidase system.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 23, Issue:1

    Topics: Aminopyrine N-Demethylase; Animals; Cytochrome P-450 Enzyme System; Dantrolene; Ethylmorphine-N-Demethylase; Hexobarbital; Hydantoins; Kinetics; Liver; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Time Factors

1979
The effects of dantrolene sodium on excretory function in the isolated perfused rat liver.
    Toxicology and applied pharmacology, 1978, Volume: 44, Issue:3

    Topics: Animals; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Dantrolene; Hydantoins; In Vitro Techniques; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Sulfobromophthalein

1978
Induction of hepatic cytochrome P-450c-dependent monooxygenase activities by dantrolene in rat.
    Biochemical pharmacology, 1987, Aug-01, Volume: 36, Issue:15

    Topics: Animals; Cytochrome P-450 Enzyme System; Dantrolene; Enzyme Induction; Epoxide Hydrolases; Glucuronosyltransferase; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1987
Interaction of dantrolene with the hepatic mixed function oxidase system.
    Research communications in chemical pathology and pharmacology, 1980, Volume: 27, Issue:3

    Topics: Animals; Cytochrome P-450 Enzyme System; Dantrolene; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Proteins; Rats

1980
Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice.
    European journal of pharmacology, 1997, Mar-26, Volume: 323, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dantrolene; Dihydropyridines; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Female; Isradipine; Lethal Dose 50; Mice; Motor Activity; Phenobarbital; Phenytoin; Random Allocation; Seizures; Valproic Acid

1997
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012