phenobarbital has been researched along with cyclosporine in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 10 (37.04) | 29.6817 |
| 2010's | 9 (33.33) | 24.3611 |
| 2020's | 1 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Erdmann, F; Fischer, G; Harris, R; Hopkins, S; Huang, Z; Murray, MG; Ribeill, Y; Scorneaux, B; Smitley, C; Wring, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Hammer, C; Modic, PK; Mraz, W | 1 |
| Bigler, S; Hänseler, E; Wad, N | 1 |
| Domergue, J; Fabre, I; Joyeux, H; Maurel, P; Pichard, L | 1 |
| Almeidal, VM; Braun, F; Christians, U; Linck, A; Sattler, M; Sewing, KF | 1 |
| Gilhar, D; Habib, G; Hoffman, A; Zohar, H | 1 |
| Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW | 1 |
| Hortin, GL; Landt, M; Smith, CH | 1 |
| Innocenti, F; Mani, S; Prado, M; Ramírez, J; Ratain, MJ; Schilsky, RL; Undevia, SD; Vogelzang, NJ | 1 |
| Adam, G; Fleck, C; Karge, E; Kuhn, UD; Lupp, A | 1 |
| Liu, XD; Yang, ZH | 1 |
| Liu, HY; Liu, X; Liu, XD; Liu, YC; Wang, GJ; Xie, L; Yang, HW; Zhang, DM | 1 |
| de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA | 1 |
| Fukui, D; Hoshino, Y; Inden, T; Katayama, M; Otaka, R; Satoh, H | 1 |
| Ballardin, BS; Bonfim, CMS; Carvalho Torres-Pereira, C; Coracin, FL; Mobile, RZ; Ribeiro, LL; Schussel, JL | 1 |
1 review(s) available for phenobarbital and cyclosporine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
2 trial(s) available for phenobarbital and cyclosporine
| Article | Year |
|---|---|
Analyses of the pattern of therapeutic drug monitoring in a university hospital laboratory. Suitability and performance of the CEDIA assays.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Quality Control; Theophylline | 1992 |
A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Area Under Curve; Camptothecin; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance, Neoplasm; Drug Therapy, Combination; Endpoint Determination; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Half-Life; Humans; Hypnotics and Sedatives; Immunosuppressive Agents; Irinotecan; Lymphoma; Male; Middle Aged; Neoplasms; Phenobarbital | 2004 |
24 other study(ies) available for phenobarbital and cyclosporine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
SCY-635, a novel nonimmunosuppressive analog of cyclosporine that exhibits potent inhibition of hepatitis C virus RNA replication in vitro.
Topics: Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cyclophilin A; Cyclosporins; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Haplorhini; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Leukocytes, Mononuclear; Mice; Molecular Structure; Rats; RNA, Viral; Virus Replication | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Impact of imipenem/cilastatin on cyclosporine metabolism and excretion.
Topics: Animals; Bile; Cilastatin; Cyclosporine; Cytosol; Imipenem; Ketoconazole; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors | 1992 |
Effect of FK 506 on human hepatic cytochromes P-450: interaction with CyA.
Topics: Cells, Cultured; Cyclosporine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Isoenzymes; Liver; Microsomes, Liver; Phenobarbital; Rifampin; Tacrolimus | 1991 |
Interactions of FK 506 and cyclosporine metabolism.
Topics: Animals; Cyclosporine; Drug Interactions; Humans; Kinetics; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Tacrolimus | 1991 |
Cyclosporin increases the CNS sensitivity to the hypnotic effect of phenobarbitone but not ethanol in rats.
Topics: Anesthesia; Animals; Brain; Cyclosporine; Drug Interactions; Ethanol; Hypnosis, Anesthetic; Infusions, Intravenous; Injections, Intramuscular; Male; Phenobarbital; Rats; Reflex | 1994 |
Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity.
Topics: Aminopyrine; Animals; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Induction; Free Radical Scavengers; Ketoconazole; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley | 1994 |
Evaluation of evacuated blood-collection tubes: effects of three types of polymeric separators on therapeutic drug-monitoring specimens.
Topics: Acrylic Resins; Blood Specimen Collection; Cell Separation; Cyclosporine; Digoxin; Drug Monitoring; Ethanol; Gentamicins; Humans; Phenobarbital; Phenytoin; Polyesters; Polymers; Silicones; Theophylline | 1993 |
In vitro investigations on the differential pro-oxidant and/or antioxidant properties of cyclosporin A and tacrolimus in human and rat liver microsomes.
Topics: Animals; Antioxidants; beta-Naphthoflavone; Cyclosporine; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Induction; Humans; Hydrogen Peroxide; Immunosuppressive Agents; In Vitro Techniques; Isoenzymes; Lipid Peroxidation; Liver; Male; Microsomes, Liver; Oxidants; Phenobarbital; Rats; Rats, Wistar; Tacrolimus | 2006 |
P-glycoprotein-mediated efflux of phenobarbital at the blood-brain barrier evidence from transport experiments in vitro.
Topics: Animals; Animals, Newborn; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Endothelial Cells; Enzyme Inhibitors; Gene Expression; Phenobarbital; Protein Transport; Rats; Rats, Sprague-Dawley; Temperature; Time Factors | 2008 |
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil | 2008 |
Tuberculosis in a patient on temozolomide: a case report.
Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary | 2009 |
Interaction of cyclosporine with phenobarbital in cats: a preliminary study.
Topics: Administration, Oral; Animals; Biological Availability; Cats; Cyclosporine; Dose-Response Relationship, Drug; Drug Interactions; Immunosuppressive Agents; Male; Phenobarbital | 2019 |
A case series of medication-related fibrovascular hyperplasia following hematopoietic stem cell transplantation for Fanconi anemia.
Topics: Amlodipine; Calcium Channel Blockers; Child; Cyclosporine; Fanconi Anemia; Female; Granuloma, Pyogenic; Hematopoietic Stem Cell Transplantation; Humans; Hyperplasia; Immunosuppressive Agents; Male; Mouth Diseases; Phenobarbital | 2021 |