phenobarbital has been researched along with cyanides in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 65 (92.86) | 18.7374 |
| 1990's | 4 (5.71) | 18.2507 |
| 2000's | 1 (1.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mannering, GJ; Peisach, J | 1 |
| Kahl, GF; Kahl, R; Kumaki, K; Nebert, DW | 1 |
| Kato, R; Sugiura, M | 1 |
| Dey, AC; Senciall, IR | 1 |
| Hiraga, K; Kawano, S | 1 |
| Matsubara, T; Tochino, Y | 1 |
| Gaylor, JL; Morris, HP; Williams, MT | 1 |
| Jänig, GR; Lassmann, G; Pecar, S; Pirrwitz, J; Rein, H; Ruckpaul, K | 1 |
| Roach, MK | 1 |
| Catignani, GL; Neal, RA | 1 |
| Berman, MC; Ivanetich, KM; Kench, JE | 1 |
| Schwab, H; Sies, H | 1 |
| Burk, RF; Masters, BS | 1 |
| Pap, A; Szarvas, F | 1 |
| Levin, W; Lu, AY; Ryan, D; West, S | 1 |
| Cavazos, R; Diaz, RG; Farooqui, MY | 1 |
| Cinicola, DP; Esposito, FM; Winek, CL | 1 |
| Achike, AE; Obidoa, O | 1 |
| DeMaster, EG; Kwon, CH; Nagasawa, HT; Shirota, FN | 1 |
| Belinsky, SA; Kari, FW; Kauffman, FC; Thurman, RG | 1 |
| Kuwahara, S; Mannering, GJ | 1 |
| Mannering, GJ | 1 |
| Gangolli, S; Wright, M | 1 |
| Hrycay, EG; O'Brien, PJ | 1 |
| Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ | 1 |
| Grundin, R; Moldéus, P; Orrenius, S; Vadi, H | 1 |
| O'Brien, PJ; Rahimtula, AD | 1 |
| Kröber, F; Lange, G; Mathes, S; Mor, G | 2 |
| Glaser, GE; Grove, I; Marino, BB; Pincus, JH | 1 |
| Miyake, Y; Mori, K; Yamano, T | 1 |
| Kurokawa, M; Yamamoto, C | 1 |
| Conney, AH; Kuntzman, R; Lu, AY; Somogyi, A; West, S | 1 |
| Bompiani, R; D'Amico, E; Galotti, T; Marchese, E; Russo, M; Terranova, T | 1 |
| Leibman, KC | 1 |
| Imai, Y; Sato, R | 1 |
| Lange, G | 1 |
| Gaylor, JL; Mason, HS; Miyake, Y | 1 |
| Strittmatter, CF; Umberger, FT | 1 |
| Ichihara, K; Kusunose, E; Kusunose, M | 1 |
| Lisboa, BP; Orrenius, S; von Bahr, C | 1 |
| Scholz, R; Thurman, RG | 1 |
| Carlson, GP; DuBois, KP | 1 |
| Carter, EA; Isselbacher, KJ | 1 |
| Hino, Y; Imai, Y; Sato, R | 1 |
| Becker, DM; Kramer, S; Viljoen, JD | 1 |
| Hildebrandt, AG | 1 |
| Oshino, N | 1 |
| Comai, K; Gaylor, JL | 1 |
| Agosin, M; Capdevila, J; Morello, A; Perry, AS | 1 |
| Nichol, AW | 1 |
| Alvares, AP; Conney, AH; Gommi, B; Welch, RM | 1 |
| Knabe, J; Strauss, D | 1 |
| Brock, N; Hohorst, HJ; Ziemann, A | 1 |
| Abernathy, CO; Guthrie, FE; Hodgson, E; Philpot, RM | 1 |
| Calabrese, RL; Gaylor, JL; Jefcoate, CR | 2 |
| Döring, HJ; Olbrisch, RR | 1 |
| Fouts, JR; Hewick, DS | 1 |
| Mannering, GJ; Sladek, NE | 2 |
| Bernacchi, AS; Castro, JA; de Castro, CR; Fernández, G; Villarruel, MC | 1 |
| Belinsky, SA; Kauffman, FC; Reinke, LA; Thurman, RG | 1 |
| Chiba, K; Imai, Y; Kamataki, T; Kitada, M; Kitagawa, H; Sato, R | 1 |
| Farooqui, MY; Piper, J; Ybarra, B | 1 |
| Abdel-Aziz, AH; Abdel-Naim, AB; Abo-Salem, O; Hamada, FM; Mostafa, AM | 1 |
| BIANCHI, B; DEMICHELLI, G; PRODANOV, E | 1 |
| BESSIN, P; BOISSIER, JR; DUMONT, C | 1 |
| GRAHAM, JD | 1 |
| Benz, FW; Nerland, DE | 1 |
1 review(s) available for phenobarbital and cyanides
| Article | Year |
|---|---|
The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Ethylamines; Hydrogen-Ion Concentration; In Vitro Techniques; Isocitrate Dehydrogenase; Methylation; Metyrapone; Microsomes, Liver; Morphinans; Oxidation-Reduction; Phenobarbital; Proadifen; Pseudomonas; Rats; Spectrum Analysis | 1972 |
69 other study(ies) available for phenobarbital and cyanides
| Article | Year |
|---|---|
A re-evaluation of the optical titrations of the 430 and 455 nm chromophore of ethyl isocyanide complexes of mamalian hepatic cytochrome P-450.
Topics: Animals; Chromatophores; Computers; Cyanides; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry | 1975 |
Association of the Ah locus with specific changes in metyrapone and ethylisocyanide binding to mouse liver microsomes.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Enzyme Induction; Genes, Dominant; Hydrogen-Ion Concentration; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mutation; Oxygenases; Phenobarbital; Protein Binding; Protein Conformation; Spectrophotometry | 1976 |
Reduction of tertiary amine N-oxides by rat liver mitochondria.
Topics: Adenosine Triphosphate; Amines; Aniline Compounds; Animals; Antimycin A; Benzothiazoles; Carbon Monoxide; Citric Acid Cycle; Cyanides; Dicarboxylic Acids; Digitonin; Imipramine; In Vitro Techniques; Male; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Phenobarbital; Piperazines; Rats; Rotenone; Thiazoles; Tricarboxylic Acids | 1977 |
Acidic steroid metabolites: biosynthesis of steroid carboxylic acids by rabbit liver microsomes and the involvement of a cytochrome P450-independent mixed function oxidase system.
Topics: Androstenes; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Female; Hydrogen-Ion Concentration; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NAD; NADP; Nitrogen; Oxidoreductases; Phenobarbital; Progesterone; Rabbits | 1978 |
Polychlorinated dibenzofurans--potent inducers of rat hepatic drug-metabolizing enzymes.
Topics: Aniline Hydroxylase; Animals; Benzofurans; Cyanides; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Flavonoids; Liver; Male; Metyrapone; Microsomes, Liver; Nitroanisole O-Demethylase; Phenobarbital; Polychlorinated Biphenyls; Rats; Spectrum Analysis; Substrate Specificity; Time Factors | 1978 |
Modification by cyanide of the aniline-binding reaction with cytochrome P-450.
Topics: Aniline Compounds; Aniline Hydroxylase; Animals; Binding Sites; Cyanides; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Kinetics; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Protein Conformation; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet | 1976 |
Characterization of microsomal methyl sterol demethylase in two Morris hepatomas.
Topics: Animals; Buffers; Carcinoma, Hepatocellular; Cholesterol; Cholestyramine Resin; Cyanides; Cytochrome c Group; Diphosphates; Edetic Acid; Liver; Liver Neoplasms; Male; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; Neoplasms, Experimental; Phenobarbital; Phosphates; Rats; Steroid Hydroxylases; Sterols | 1976 |
Spin-labelled isocyanides as stereochemical probes for the active center of cytochrome P-450.
Topics: Animals; Binding Sites; Cyanides; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Male; Microsomes, Liver; Phenobarbital; Protein Conformation; Rabbits | 1979 |
Microsomal ethanol oxidation: activity in vitro and in vivo.
Topics: Animals; Azides; Carbon Monoxide; Catalase; Cyanides; Ethanol; Hydrogen Peroxide; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Pyrazoles; Rats | 1975 |
Evidence for the formation of a protein bound hydrodisulfide resulting from the microsomal mixed function oxidase catalyzed desulfuration of carbon disulfide.
Topics: Animals; Carbon Disulfide; Chromatography, Gel; Cyanides; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Rats; Thiocyanates | 1975 |
The effects of halothane on hepatic microsomal electron transfer.
Topics: Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Electron Transport Complex IV; Halothane; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Phenobarbital; Rats; Stearoyl-CoA Desaturase | 1975 |
A new organ spectrophotometer for sensitive dual-wavelength absorbance measurement and spectral scanning of intact perfused organs.
Topics: Aminopyrine; Animals; Cyanides; Liver; Perfusion; Phenobarbital; Rats; Spectrometry, Fluorescence; Spectrophotometry | 1978 |
Some effects of selenium deficiency on the hepatic microsomal cytochrome P-450 system in the rat.
Topics: Animals; Binding Sites; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Ethylmorphine-N-Demethylase; Male; Metyrapone; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Pentobarbital; Phenobarbital; Protein Binding; Rats; Selenium; Sleep | 1975 |
Effect of alpha-pinene on the mixed function microsomal oxidase system in the rat.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cyanides; Cytochrome P-450 Enzyme System; Enzyme Induction; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Terpenes | 1976 |
Multiple forms of cytochrome P-450 in phenobarbital- and 3-methylcholanthrene-treated rats. Separation and spectral properties.
Topics: Amines; Animals; Benzopyrenes; Benzphetamine; Chromatography, DEAE-Cellulose; Cyanides; Cytochrome P-450 Enzyme System; Hemeproteins; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Protein Conformation; Rats; Spectrophotometry | 1975 |
Metabolism of methacrylonitrile to cyanide: in vitro studies.
Topics: Animals; Biotransformation; Cyanides; Cytochrome P-450 Enzyme System; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Methacrylates; Microsomes, Liver; NADP; Nitriles; Oxygen Consumption; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Subcellular Fractions | 1990 |
The stability of several compounds in formalin fixed tissues and formalin-blood solutions.
Topics: Carbon Monoxide; Carboxyhemoglobin; Cyanides; Desipramine; Diazepam; Drug Stability; Embalming; Fixatives; Formaldehyde; Humans; Liver; Phenobarbital; Phenytoin; Postmortem Changes | 1990 |
Hepatic effects of phenobarbitone in female mice fed sublethal levels of dietary cyanide.
Topics: Aniline Hydroxylase; Animals; Chemical and Drug Induced Liver Injury; Cyanides; Drug Interactions; Female; Glucose-6-Phosphatase; Liver; Mice; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Potassium Cyanide | 1986 |
Metabolism of cyanamide to cyanide and an inhibitor of aldehyde dehydrogenase (ALDH) by rat liver microsomes.
Topics: Aldehyde Dehydrogenase; Amitrole; Animals; Cyanamide; Cyanides; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1987 |
Effect of beta-naphthoflavone on mitochondrial supply of reducing equivalents for monooxygenation in periportal and pericentral regions of the liver lobule.
Topics: 6-Aminonicotinamide; 7-Alkoxycoumarin O-Dealkylase; Ammonia; Animals; Benzoflavones; beta-Naphthoflavone; Corn Oil; Cyanides; Cytochrome P-450 Enzyme System; Fasting; Flavonoids; Liver; Mitochondria; Oxidation-Reduction; Oxygenases; Pentose Phosphate Pathway; Phenobarbital; Rats | 1987 |
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats | 1985 |
Properties of cytochrome P-450 as affected by environmental factors: qualitative changes due to administration of polycyclic hydrocarbons.
Topics: Animals; Binding Sites; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Transport; Environment; Hydrocarbons; Hydrogen-Ion Concentration; Methylcholanthrene; Microsomes, Liver; Morpholines; Phenobarbital; Polycyclic Compounds; Spectrum Analysis; Thyroxine | 1971 |
The histochemical demonstration of aniline hydroxylase activity in rat liver.
Topics: Acetone; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Diazonium Compounds; Ethanol; Female; Formaldehyde; Histocytochemistry; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitrogen; Phenobarbital; Phenols; Rats; Staining and Labeling; Time Factors | 1971 |
Microsomal electron transport. I. Reduced nicotinamide adenine dinucleotide phosphate-cytochrome c reductase and cytochrome P-450 as electron carriers in microsomal NADPH-peroxidase activity.
Topics: Adrenal Glands; Animals; Cattle; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Hydrogen-Ion Concentration; Immune Sera; Kinetics; Male; Microsomes; Microsomes, Liver; NAD; NADP; Organ Specificity; Osmolar Concentration; Oxidoreductases; Peroxidases; Peroxides; Phenobarbital; Rabbits; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Steroids; Trypsin | 1973 |
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium | 1973 |
A study of drug metabolism linked to cytochrome P-450 in isolated rat-liver cells.
Topics: Adenosine Triphosphate; Alprenolol; Animals; Antimycin A; Cell Survival; Cyanides; Cytochrome P-450 Enzyme System; Cytoplasm; Gluconeogenesis; Histocytochemistry; In Vitro Techniques; Lactates; Liver; Malate Dehydrogenase; Male; Metyrapone; Microsomes, Liver; Mitochondria, Liver; NADP; Oxygen Consumption; Pentosephosphates; Phenobarbital; Rats; Rotenone; Spectrophotometry; Starvation; Uncoupling Agents | 1974 |
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450.
Topics: Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Coumarins; Cyanides; Cytochrome P-450 Enzyme System; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Phenobarbital; Phenols; Phenylenediamines; Proadifen; Rabbits; Rats; Sodium Dodecyl Sulfate; Species Specificity; Superoxide Dismutase; Time Factors | 1974 |
[Change in the affinity of isolated liver microsomes for aniline, N-ethylaniline, oxygen, ethyl isocyanide and carbon monoxide by the treatment of young rabbits with phenobarbital].
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Enzyme Induction; Liver; Microsomes; Mixed Function Oxygenases; Oxygen; Phenobarbital; Rabbits; Stimulation, Chemical | 1968 |
Studies on the mechanism of action of diphenylhydantoin.
Topics: Adenosine Triphosphatases; Animals; Biological Transport; Crustacea; Cyanides; Hypoxia; Neurons; Ouabain; Peripheral Nerves; Phenobarbital; Phenytoin; Potassium; Schwann Cells; Sodium; Tetrodotoxin; Trimethadione | 1970 |
[Qualitative changes in liver microsomes of phenobarbital-treated rabbits. Changes in spectral dissociation constants (Ks) of aniline and N-ethylaniline, in the apparent Michaelis constants (Km) for hydroxylation of these substrates, and in affinity of th
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Enzyme Induction; Kinetics; Microsomes, Liver; Oxygen; Phenobarbital; Rabbits | 1970 |
A study on some spectral properties of P-450 in a submicrosomal particle.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Heme; Liver; Microsomes; Nitric Oxide; Oxidation-Reduction; Phenobarbital; Proteins; Rabbits; Spectrophotometry | 1969 |
Synaptic potentials recorded in brain slices and their modification by changes in the level of tissue ATP.
Topics: Adenosine Triphosphate; Animals; Chlorpromazine; Culture Techniques; Cyanides; Electric Stimulation; Evoked Potentials; Fluorometry; Glycolysis; Guinea Pigs; Limbic System; Oxidative Phosphorylation; Oxygen; Partial Pressure; Phenobarbital; Synaptic Transmission | 1970 |
Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes.
Topics: Aminopyrine N-Demethylase; Animals; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Nitriles; Organ Size; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone; Rats; Spectrophotometry | 1972 |
Energy coupling and extramitochondrial electron transport in slices of Morris hepatoma 3924 A.
Topics: Aminopyrine; Animals; Antimycin A; Biological Transport; Carcinoma, Hepatocellular; Cyanides; Dinitrophenols; Electrons; Liver Neoplasms; Mitochondria, Liver; Neoplasms, Experimental; Oligomycins; Ouabain; Oxygen Consumption; Phenobarbital; Rats; Rotenone; Succinates | 1974 |
Metabolism of trichloroethylene in liver microsomes. I. Characteristics of the reaction.
Topics: Animals; Chloral Hydrate; Chloromercuribenzoates; Cyanides; Dogs; Enzymes; Ethylmaleimide; Flavin Mononucleotide; Freeze Drying; In Vitro Techniques; Iodoacetates; Ions; Liver; Methylene Blue; Microsomes; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Trichloroethylene; Vitamin K | 1965 |
Substrate interaction with hydroxylase system in liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Cyanides; Cytochromes; Guinea Pigs; In Vitro Techniques; Liver; Microsomes; Mixed Function Oxygenases; NADP; Phenacetin; Phenobarbital; Rabbits; Rats; Spectrophotometry | 1966 |
[Hydroxylase activity and hemoprotein content of microsomes from rabbit liver].
Topics: Aniline Compounds; Animals; Cyanides; Cytochromes; Female; Liver; Male; Microsomes; Mixed Function Oxygenases; NAD; NADP; Phenobarbital; Rabbits | 1968 |
Properties of a submicrosomal particle containing P-450 and flavoprotein.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Liver; Methods; Microsomes; NADP; Nitric Oxide; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Pigments, Biological; Proteins; Rabbits; Riboflavin; Spectrophotometry | 1968 |
Oxidative enzyme components of avian liver microsomes. Changes during embryonic development and the effects of phenobarbital administration.
Topics: Animals; Chick Embryo; Chickens; Cyanides; Cytochromes; Electron Transport; Liver; Microsomes; NAD; NADP; Niacinamide; Oxidoreductases; Phenobarbital; Spectrophotometry; Spectrum Analysis | 1969 |
Microsomal hydroxylation of decane.
Topics: Alcohols; Alkanes; Aniline Compounds; Animals; Carbon Isotopes; Carbon Monoxide; Cattle; Chick Embryo; Columbidae; Cyanides; Fatty Acids; Glycols; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lung; Male; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Phenobarbital; Proadifen; Rabbits; Rats | 1969 |
Influence of phenobarbital pretreatment on the in vitro ring A reduction of delta4-3-oxo-steroids in rat liver microsomes.
Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Chromatography, Thin Layer; Cyanides; Cytochromes; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Rats; Stimulation, Chemical | 1969 |
Mixed function oxidation in perfused rat liver. The effect of aminopyrine on oxygen uptake.
Topics: Aminopyrine; Animals; Antimycin A; Cyanides; Depression, Chemical; Drug Synergism; Fasting; Fluorometry; Hemoglobins; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Models, Biological; NADP; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Rats; Stimulation, Chemical; Time Factors | 1969 |
Studies on the induction of nitroreductase activity by DDT and phenobarbital.
Topics: Aminobenzoates; Animals; Benzoates; Cyanides; DDT; Enzyme Induction; Liver; Male; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats; Sodium; Venoms | 1970 |
The role of microsomes in the hepatic metabolism of ethanol.
Topics: Acetates; Adenine Nucleotides; Aerobiosis; Amino Alcohols; Anaerobiosis; Animals; Azides; Bile Acids and Salts; Carbon Monoxide; Catalase; Cell Fractionation; Chlorides; Chloromercuribenzoates; Copper; Cyanides; Diet; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Female; Hot Temperature; Hydrogen Peroxide; Iron; Liver; Mercury; Microsomes, Liver; NAD; NADP; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Sulfides; Triazoles | 1971 |
Induction by phenobarbital of hepatic microsomal drug-metabolizing enzyme system in partially hepatectomized rats.
Topics: Aminopyrine N-Demethylase; Animals; Body Weight; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Dithionite; Enzyme Induction; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Spectrophotometry; Time Factors | 1974 |
Delta-aminolevulinic acid uptake by rabbit brain cerebral cortex.
Topics: Allosteric Regulation; Amino Acids; Aminolevulinic Acid; Animals; Biological Transport, Active; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cyanides; Dinitrophenols; In Vitro Techniques; Inulin; Ketoglutaric Acids; Kinetics; Levulinic Acids; Male; Osmolar Concentration; Ouabain; Phenobarbital; Porphobilinogen; Potassium; Rabbits; Sodium; Temperature; Time Factors | 1974 |
The dynamic behavior during dietary induction of the terminal enzyme (cyanide-sensitive factor) of the stearyl CoA desaturation system of rat liver microsomes.
Topics: Animals; Carbon Isotopes; Cell Membrane; Coenzyme A; Cresols; Cyanides; Cytochromes; Diet; Electron Transport; Enzyme Induction; Fasting; Half-Life; Kinetics; Liver; Male; Microsomes, Liver; Multienzyme Complexes; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry; Stearic Acids; Time Factors | 1972 |
Existence and separation of three forms of cytochrome P-450 from rat liver microsomes.
Topics: Amines; Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Deoxycholic Acid; Enzyme Induction; Ethanol; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Solubility; Spectrophotometry; Subtilisins | 1973 |
Some spectral properties of cytochrome P-450 from microsomes isolated from control, phenobarbital- and naphthalene-treated houseflies.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Houseflies; Ligands; Microsomes; Naphthalenes; Nucleic Acid Conformation; Phenobarbital; Proadifen; Protein Conformation; Spectrophotometry; Spectrophotometry, Ultraviolet | 1973 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
Effect of enzyme induction on the metabolism of benzo(a)pyrene and 3'-methyl-4-monomethylaminoazobenzene in the pregnant and fetal rat.
Topics: Animals; Azo Compounds; Benzopyrenes; Carbon Monoxide; Carcinogens; Cyanides; Cytochromes; Dealkylation; Enzyme Induction; Female; Fetus; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Pregnancy; Rats; Spectrophotometry; Tritium | 1972 |
[Synthesis of optically active N-methylbarbiturates. 12. Barbituric acid derivatives].
Topics: Acetates; Barbiturates; Codeine; Cyanides; Hexobarbital; Methylation; Optical Rotation; Phenobarbital; Quinine | 1972 |
4-Ketocyclophosphamide, a metabolite of cyclophosphamide. Formation, chemical and biological properties.
Topics: Alkylation; Animals; Chemical Phenomena; Chemistry; Cyanides; Cyclophosphamide; Dehydration; Ketones; Liver; Male; Phenobarbital; Rats | 1971 |
Inductive effects of 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane(DDT), phenobarbital, and benzpyrene on microsomal cytochrome B450, ethyl isocyanide spectra, and metabolism in vivo of zoxazolamine and hexobarbital in the mouse.
Topics: Animals; Benzopyrenes; Cyanides; Cytochrome P-450 Enzyme System; DDT; Enzyme Induction; Hexobarbital; Male; Mice; Microsomes, Liver; Paralysis; Phenobarbital; Proteins; Sleep; Spectrum Analysis; Time Factors; Zoxazolamine | 1971 |
Ligand interaction with hemoprotein P-450. 3. The use of n-octylamine and ethyl isocyanide difference spectroscopy in the quantitative determination of high- and low-spin P-450.
Topics: Adrenal Glands; Amines; Animal Feed; Animals; Cattle; Cyanides; Heme; Male; Methods; Microsomes, Liver; Oxytetracycline; Phenobarbital; Protein Binding; Proteins; Rabbits; Spectrum Analysis | 1970 |
[Electrocorticogram, steady potential of the brain and energy-rich phosphate fractions of the cerebral cortex during anesthetic overdosage, ischemia and cyanide poisoning].
Topics: Adenine Nucleotides; Adenosine Triphosphate; Anesthetics; Animals; Cerebral Cortex; Chloral Hydrate; Chlorobutanol; Cyanides; Depression, Chemical; Electroencephalography; Ethers; Female; Guinea Pigs; Hexobarbital; Ischemia; Male; Membrane Potentials; Methoxyflurane; Pentobarbital; Phenobarbital; Phosphates; Phosphocreatine; Propanidid; Rats; Urethane | 1970 |
Effects of storage on hepatic microsomal cytochromes and substrate-induced difference spectra.
Topics: Aniline Compounds; Animals; Benzphetamine; Cyanides; Cytochromes; Drug Storage; Enzyme Induction; Heme; Hemoglobins; Hexobarbital; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methemoglobin; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Spectrum Analysis; Time Factors | 1970 |
Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.
Topics: Animals; Benzene Derivatives; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Female; Formaldehyde; Kinetics; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Valerates | 1969 |
Ligand interactions with cytochrome P-450. I. Binding of primary amines.
Topics: Alcohols; Alkanes; Amines; Animals; Cyanides; Cytochromes; Liver; Male; Methylcholanthrene; Microsomes; Phenobarbital; Rabbits; Spectrophotometry; Stimulation, Chemical | 1969 |
Evidence for a new P-450 hemoprotein in hepatic microsomes from methylcholanthrene treated rats.
Topics: Animals; Cyanides; Cytochromes; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Methylcholanthrene; Microsomes; Morphine; Phenobarbital; Rats; Spectrophotometry; Transferases | 1966 |
Carbon tetrachloride activation by highly purified liver mitochondrial preparations.
Topics: Animals; Biotransformation; Carbon Tetrachloride; Cyanides; Glucose-6-Phosphatase; In Vitro Techniques; Male; Microscopy, Electron; Microsomes, Liver; Mitochondria, Liver; NADP; Phenobarbital; Rats; Rats, Inbred Strains | 1984 |
Inhibition of p-nitroanisole O-demethylation in perfused rat liver by potassium cyanide.
Topics: Animals; Cyanides; Electron Transport Complex IV; Female; Liver; Microsomes, Liver; Nitroanisole O-Demethylase; Oxidoreductases; Pentosephosphates; Perfusion; Phenobarbital; Potassium Cyanide; Rats; Rats, Inbred Strains | 1983 |
Enhancement by cyanide of aniline p-hydroxylation activity in rat liver microsomes.
Topics: 2,2'-Dipyridyl; Acetone; Aniline Hydroxylase; Animals; Aryl Hydrocarbon Hydroxylases; Cyanides; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Potassium Cyanide; Rats | 1980 |
Metabolism of allylnitrile to cyanide: in vitro studies.
Topics: Animals; Biotransformation; Cyanides; Hydrogen-Ion Concentration; Magnesium Chloride; Male; Microsomes, Liver; NADP; Nitriles; Phenobarbital; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 1993 |
Renal metabolism of acrylonitrile to cyanide: in vitro studies.
Topics: Acrylonitrile; Animals; Benzimidazoles; Cyanides; Cytochrome P-450 Enzyme System; Ethanol; Fomepizole; Hydrogen-Ion Concentration; Kidney; Male; Methylcholanthrene; Microsomes; NADP; Phenobarbital; Proadifen; Pyrazoles; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Sulfhydryl Compounds; Temperature | 1999 |
[Influence of the cyanide ion on the chemoluminescent reaction of luminol with persulfate in an alkaline medium].
Topics: Cyanides; Luminol; Phenobarbital; Sulfates | 1961 |
[ON A NEW METHOD OF RECORDING MOVEMENT IN THE LABORATORY ANIMAL MAINTAINED IN ITS REARING ENVIRONMENT--ITS APPLICATION TO THE STUDY OF SOME BEHAVIOR-MODIFYING AGENTS].
Topics: Amphetamine; Amphetamines; Animals; Animals, Laboratory; Barbiturates; Behavior, Animal; Caffeine; Chlorpromazine; Cinnamates; Cyanides; Heterocyclic Compounds; Hypnotics and Sedatives; Injections, Intraperitoneal; Mice; Morphine; Movement; Pharmacology; Phenobarbital; Research; Reserpine | 1964 |
HYDROXYCOBALAMIN AS AN ANTIDOTE TO ACRYLONITRILE.
Topics: Acrylonitrile; Animals; Antidotes; Blood Pressure; Cell Respiration; Cyanides; Dogs; Fumigation; Heart Rate; Hydroxocobalamin; Injections, Subcutaneous; Mice; Pesticides; Pharmacology; Phenobarbital; Pulse; Research; Respiration; Thiosulfates; Toxicology | 1965 |
Effect of cytochrome P450 inhibitors and anticonvulsants on the acute toxicity of acrylonitrile.
Topics: Acrylonitrile; Animals; Anticonvulsants; Carcinogens; Central Nervous System Depressants; Cyanides; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Ethanol; Imidazoles; Male; Phenobarbital; Phenytoin; Proadifen; Rats; Rats, Sprague-Dawley; Seizures; Time Factors | 2005 |