phenobarbital and clonidine

phenobarbital has been researched along with clonidine in 43 studies

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-19906 (13.95)18.7374
1990's6 (13.95)18.2507
2000's13 (30.23)29.6817
2010's13 (30.23)24.3611
2020's5 (11.63)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Beubler, E; Lembeck, F; Stolze, A1
Poignant, JC; Rismondo, N1
Waldeck, B1
Schiff, I; Walsh, B1
Dhasmana, KM; Fokker, WA; Spilker, BA1
Handley, SL1
Kuprys, R; Tabakoff, B1
Campbell, M; Cueva, JE1
Smith, JA1
Ikizler, Y; Koren, G; Selby, P; Theis, JG1
van Luijtelaar, EL1
Lung, MA1
Barton, DL; Loprinzi, CL; Rhodes, D1
Cole, MJ; Jeffery, HE; Osborn, DA3
Baruch, EM; Deerfield, LJ; Rosenberg, MH1
Barton, D; Loprinzi, CL; Stearns, V1
Bastanier, C; Beske, F; Esmaeili, A; Keinhorst, AK; Schlösser, R; Schuster, T1
Bio, LL; Poon, CY; Siu, A1
Chamberlain, S; Kopcza, K; Shah, B; Singh, R; Surran, B; Visintainer, P1
Coyle, MG1
Singh, R; Visintainer, PF1
Bamford, A; Clarke, A; Crowe, BH; Hacohen, Y; Lim, M; Lin, JP; Pullaperuma, SP; Sancho-Shimizu, V; Tudor-Williams, G; Vincent, A1
McPherson, C1
Fontaine, GV; Fraser, GL; Gagnon, DJ; Riker, RR1
Jones, HE; Kraft, WK1
Castro, R; Chyi, L; Clemans-Cope, L; Cong, AS; Holla, N; Huang, A; Kenney, GM; Lee, HC; Taylor, KJ1
Brusseau, C; Burnette, T; Heidel, RE1
Berkey, SD; Crowley, M; Czynski, AJ; Das, A; Devlin, LA; Fuller, JF; Higgins, RD; Kiefer, AS; Lester, BM; Merhar, SL; Newman, S; Ounpraseuth, S; Poindexter, BB; Sánchez, PJ; Simon, AE; Smith, MC; Smith, PB; Thombre, V; Whalen, BL; Young, LW1
Davey, JG; Martin, J; Osborn, DA; Zankl, A2

Reviews

14 review(s) available for phenobarbital and clonidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Vasomotor flushes.
    Annals of the New York Academy of Sciences, 1990, Volume: 592

    Topics: Adrenergic alpha-Agonists; Belladonna Alkaloids; Clonidine; Drug Combinations; Ergotamines; Estrogen Replacement Therapy; Female; Flushing; Humans; Methysergide; Phenobarbital; Progestins; Terminology as Topic; Vasomotor System

1990
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10

    Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents

1995
Current management of the neonatal abstinence syndrome: a critical analysis of the evidence.
    Biology of the neonate, 1997, Volume: 71, Issue:6

    Topics: Analgesics, Opioid; Anticonvulsants; Antipsychotic Agents; Chlorpromazine; Clinical Trials as Topic; Clonidine; Diazepam; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Infant, Newborn; MEDLINE; Methadone; Morphine; Neonatal Abstinence Syndrome; Opium; Parasympatholytics; Phenobarbital; Sympatholytics

1997
Management of hot flashes in breast-cancer survivors.
    The Lancet. Oncology, 2001, Volume: 2, Issue:4

    Topics: Antidepressive Agents; Belladonna Alkaloids; Breast Neoplasms; Clonidine; Drug Combinations; Ergotamines; Estrogens; Female; Hot Flashes; Humans; Methysergide; Phenobarbital; Progesterone Congeners; Survivors

2001
Sedatives for opiate withdrawal in newborn infants.
    The Cochrane database of systematic reviews, 2002, Issue:3

    Topics: Chlorpromazine; Clonidine; Diazepam; Humans; Hypnotics and Sedatives; Infant, Newborn; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Randomized Controlled Trials as Topic

2002
Sedatives for opiate withdrawal in newborn infants.
    The Cochrane database of systematic reviews, 2005, Jul-20, Issue:3

    Topics: Chlorpromazine; Clonidine; Diazepam; Humans; Hypnotics and Sedatives; Infant, Newborn; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Randomized Controlled Trials as Topic

2005
Sedatives for opiate withdrawal in newborn infants.
    The Cochrane database of systematic reviews, 2010, Oct-06, Issue:10

    Topics: Chlorpromazine; Clonidine; Diazepam; Humans; Hypnotics and Sedatives; Infant, Newborn; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Randomized Controlled Trials as Topic

2010
Update on the pharmacologic management of neonatal abstinence syndrome.
    Journal of perinatology : official journal of the California Perinatal Association, 2011, Volume: 31, Issue:11

    Topics: Benzodiazepines; Buprenorphine; Clonidine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Narcotics; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy

2011
Pharmacotherapy for Neonatal Abstinence Syndrome: Choosing the Right Opioid or No Opioid at All.
    Neonatal network : NN, 2016, Volume: 35, Issue:5

    Topics: Analgesics; Buprenorphine; Clonidine; Drug Therapy, Combination; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Morphine; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Phenobarbital

2016
Repurposing Valproate, Enteral Clonidine, and Phenobarbital for Comfort in Adult ICU Patients: A Literature Review with Practical Considerations.
    Pharmacotherapy, 2017, Volume: 37, Issue:10

    Topics: Administration, Oral; Administration, Sublingual; Adult; Clonidine; Critical Illness; Drug Repositioning; Humans; Hypnotics and Sedatives; Intensive Care Units; Patient Comfort; Phenobarbital; Valproic Acid

2017
Analgesia, Opioids, and Other Drug Use During Pregnancy and Neonatal Abstinence Syndrome.
    Clinics in perinatology, 2019, Volume: 46, Issue:2

    Topics: Analgesia, Obstetrical; Analgesics; Analgesics, Opioid; Breast Feeding; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Clonidine; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Kangaroo-Mother Care Method; Maternal-Fetal Exchange; Methadone; Neonatal Abstinence Syndrome; Occupational Therapy; Opiate Substitution Treatment; Opioid-Related Disorders; Pain Management; Patient Education as Topic; Phenobarbital; Physical Therapy Modalities; Pregnancy; Pregnancy Complications; Rooming-in Care

2019
Sedatives for opioid withdrawal in newborn infants.
    The Cochrane database of systematic reviews, 2021, 05-18, Volume: 5

    Topics: Bias; Chlorpromazine; Clonidine; Diazepam; Humans; Hypnotics and Sedatives; Infant, Newborn; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Phenobarbital; Randomized Controlled Trials as Topic; Treatment Outcome

2021
Opioid treatment for opioid withdrawal in newborn infants.
    The Cochrane database of systematic reviews, 2021, 07-07, Volume: 7

    Topics: Buprenorphine; Chlorpromazine; Clonidine; Diazepam; Humans; Hypnotics and Sedatives; Infant, Newborn; Methadone; Morphine; Narcotics; Neonatal Abstinence Syndrome; Opioid-Related Disorders; Opium; Phenobarbital; Randomized Controlled Trials as Topic

2021

Trials

2 trial(s) available for phenobarbital and clonidine

ArticleYear
A prospective comparison of treatments for symptomatic hot flushes following endocrine therapy for carcinoma of the prostate.
    The Journal of urology, 1994, Volume: 152, Issue:1

    Topics: Aged; Androgen Antagonists; Clonidine; Diethylstilbestrol; Ergotamine; Flushing; Gonadotropin-Releasing Hormone; Humans; Male; Megestrol; Megestrol Acetate; Orchiectomy; Phenobarbital; Prostatic Neoplasms

1994
Efficacy of clonidine versus phenobarbital in reducing neonatal morphine sulfate therapy days for neonatal abstinence syndrome. A prospective randomized clinical trial.
    Journal of perinatology : official journal of the California Perinatal Association, 2013, Volume: 33, Issue:12

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Analysis of Variance; Clonidine; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Male; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Prospective Studies

2013

Other Studies

27 other study(ies) available for phenobarbital and clonidine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
[Interactions between oxygen under high pressure and drugs (author's transl)].
    Wiener klinische Wochenschrift, 1977, Apr-15, Volume: 89, Issue:8

    Topics: Acetazolamide; Animals; Clonidine; Drug Antagonism; Drug Interactions; Drug Synergism; Guanethidine; Hyperbaric Oxygenation; Methamphetamine; Mice; Oxygen; Phenobarbital; Propranolol; Reserpine; Succinates; Tetrazoles

1977
[Influence of the administration of psychopharmacological compounds on the take up time of an alimentary material in the hamster and a study of the associated behaviour (author's transl)].
    Psychopharmacologia, 1975, Jul-23, Volume: 43, Issue:1

    Topics: Animals; Apomorphine; Behavior, Animal; Chlorpromazine; Clonidine; Cricetinae; Dextroamphetamine; Diazepam; Feeding Behavior; Fenfluramine; Humans; Imipramine; Male; Meprobamate; Mesocricetus; Morphine; Motor Activity; Phenobarbital; Piribedil; Psychotropic Drugs; Stereotyped Behavior; Sulpiride; Time Factors

1975
On the interaction between caffeine and barbiturates with respect to locomotor activity and brain catecholamines.
    Acta pharmacologica et toxicologica, 1975, Volume: 36, Issue:2

    Topics: Animals; Brain; Caffeine; Clonidine; Dopamine; Drug Interactions; Female; Mice; Motor Activity; Norepinephrine; Pentobarbital; Phenobarbital; Piribedil; Reserpine

1975
Peripheral cardiovascular effects, in the pithed rat, of compounds used in the treatment of hypertension.
    British journal of pharmacology, 1972, Volume: 46, Issue:3

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Clonidine; Cordotomy; Diazoxide; Electric Stimulation; Ergotamine; Guanethidine; Hydrochlorothiazide; Iproniazid; Male; Mecamylamine; Methyldopa; Pargyline; Phenobarbital; Rats; Reserpine; Sympathetic Nervous System; Thiocyanates; Trimethaphan

1972
The pinna reflex and its inhibition by clonidine: relationship to sedation and quantitation of central alpha 2-antagonist potency.
    The Journal of pharmacy and pharmacology, 1984, Volume: 36, Issue:7

    Topics: Adrenergic alpha-Antagonists; Animals; Brain; Chlorpromazine; Clonidine; Ear, External; Hypnotics and Sedatives; Male; Mice; Phenobarbital; Reflex

1984
Prenatal phenobarbital treatment and temperature-controlling dopamine receptors.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 18, Issue:3

    Topics: Animals; Apomorphine; Body Temperature Regulation; Brain; Clonidine; Dose-Response Relationship, Drug; Female; Hypothalamus; Male; Mice; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, Dopamine

1983
Spike-wave discharges and sleep spindles in rats.
    Acta neurobiologiae experimentalis, 1997, Volume: 57, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Anti-Anxiety Agents; Clonidine; Electroencephalography; Flunitrazepam; Frontal Lobe; Hypnotics and Sedatives; Male; Phenobarbital; Rats; Rats, Inbred Strains; Sleep; Thalamus

1997
Autonomic nervous control of venous pressure and secretion in submandibular gland of anesthetized dogs.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Acetylcholine; Anesthesia, General; Animals; Arteries; Autonomic Nervous System; Blood Pressure; Clonidine; Dogs; Electric Stimulation; Female; Isoproterenol; Jugular Veins; Male; Parasympathetic Nervous System; Phenobarbital; Phentolamine; Phenylephrine; Prazosin; Propranolol; Pulse; Regional Blood Flow; Saliva; Submandibular Gland; Vasoactive Intestinal Peptide; Veins; Yohimbine

1998
Two cases of severe gamma-hydroxybutyrate withdrawal delirium on a psychiatric unit: recommendations for management.
    The American journal of drug and alcohol abuse, 2003, Volume: 29, Issue:2

    Topics: Adult; Anticonvulsants; Antihypertensive Agents; Clonazepam; Clonidine; Delirium; Hospitalization; Humans; Lorazepam; Male; Phenobarbital; Practice Guidelines as Topic; Psychoses, Substance-Induced; Sodium Oxybate; Substance Withdrawal Syndrome

2003
Centrally active nonhormonal hot flash therapies.
    The American journal of medicine, 2005, Dec-19, Volume: 118 Suppl 12B

    Topics: Amines; Antidepressive Agents; Antihypertensive Agents; Belladonna Alkaloids; Clonidine; Cyclohexanecarboxylic Acids; Drug Combinations; Ergotamines; Female; Gabapentin; gamma-Aminobutyric Acid; Hot Flashes; Humans; Menopause; Methyldopa; Methysergide; Phenobarbital

2005
Treatment of neonatal abstinence syndrome with clonidine and chloral hydrate.
    Acta paediatrica (Oslo, Norway : 1992), 2010, Volume: 99, Issue:2

    Topics: Blood Pressure; Chloral Hydrate; Clonidine; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Pregnancy; Retrospective Studies; Treatment Outcome

2010
Adjunctive therapy for neonatal opioid dependence: do we really know what's best?
    Journal of perinatology : official journal of the California Perinatal Association, 2014, Volume: 34, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Clonidine; Female; Humans; Male; Morphine; Neonatal Abstinence Syndrome; Phenobarbital

2014
Adjunctive therapy for neonatal abstinence syndrome: why not personalize it for each infant based on their in-utero exposure?
    Journal of perinatology : official journal of the California Perinatal Association, 2014, Volume: 34, Issue:7

    Topics: Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Clonidine; Female; Humans; Male; Morphine; Neonatal Abstinence Syndrome; Phenobarbital

2014
Pediatric Herpes Simplex Virus Encephalitis Complicated by N-Methyl-D-aspartate Receptor Antibody Encephalitis.
    Journal of the Pediatric Infectious Diseases Society, 2015, Volume: 4, Issue:2

    Topics: Acyclovir; Anti-N-Methyl-D-Aspartate Receptor Encephalitis; Antiviral Agents; Autoantibodies; Clonidine; Diazepam; Encephalitis, Herpes Simplex; Encephalomalacia; Female; Fever; Humans; Immunocompromised Host; Immunosuppression Therapy; Infant; Leukoencephalopathies; Movement Disorders; Neurological Rehabilitation; Pakistan; Paresis; Phenobarbital; Phenytoin; Plasmapheresis; Receptors, N-Methyl-D-Aspartate; Seizures; Trihexyphenidyl; United Kingdom; Valproic Acid

2015
Neonatal abstinence syndrome management in California birth hospitals: results of a statewide survey.
    Journal of perinatology : official journal of the California Perinatal Association, 2020, Volume: 40, Issue:3

    Topics: Analgesics, Opioid; Breast Feeding; California; Clonidine; Health Care Surveys; Humans; Infant Care; Infant, Newborn; Inservice Training; Neonatal Abstinence Syndrome; Opiate Substitution Treatment; Phenobarbital; Severity of Illness Index

2020
Clonidine versus phenobarbital as adjunctive therapy for neonatal abstinence syndrome.
    Journal of perinatology : official journal of the California Perinatal Association, 2020, Volume: 40, Issue:7

    Topics: Analgesics, Opioid; Clonidine; Humans; Infant, Newborn; Length of Stay; Methadone; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Prospective Studies

2020
Phenobarbital and Clonidine as Secondary Medications for Neonatal Opioid Withdrawal Syndrome.
    Pediatrics, 2021, Volume: 147, Issue:3

    Topics: Analgesics; Analgesics, Opioid; Clonidine; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Infant, Newborn; Length of Stay; Linear Models; Male; Morphine; Neonatal Abstinence Syndrome; Phenobarbital; Retrospective Studies

2021