phenobarbital and chlorine

phenobarbital has been researched along with chlorine in 84 studies

Research

Studies (84)

Timeframe	Studies, this research(%)	All Research%
pre-1990	67 (79.76)	18.7374
1990's	12 (14.29)	18.2507
2000's	4 (4.76)	29.6817
2010's	1 (1.19)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barker, JL; Macdonald, RL	1
Jooste, PL; Schoeman, JJ; Strydom, NB; Wolfswinkel, JM	1
Behr, K; Moldowan, MJ	1
Campbell, RL; Hettrick, JM; Nigro, ND; Suppnick, JD	1
Ginsberg-Fellner, F; Primack, WA	1
Allan, AM; Baier, LD; Zhang, X	2
Choi, YM; Jang, SH; Lee, MG; Lee, SH	1
Choi, YM; Kim, SH; Lee, MG	1
Bock, KW; Kobusch, AB	1
Cañadas, S; Giménez, A; González, MP; Sánchez, C	1
Donoff, B; McWade, D; Rangachari, PK	1
Allan, AM; Gallaher, EJ; Gionet, SE; Harris, RA	1
Macdonald, RL; Rogers, CJ; Twyman, RE	2
Dekeyser, J; Huyghens, L; Maes, V; Sevens, C	1
Bjondahl, K; Möttönen, M; Nieminen, L	1
Fouts, JR; Peters, MA	1
Estabrook, RW; Franklin, MR	1
Estabrook, RW; Hildebrandt, A	1
Carter, EA; Isselbacher, KJ	1
Krag, B; Skadhauge, E	1
Conolly, RB; Jaeger, RJ; Moslen, MT; Murphy, SD; Reynolds, ES; Szabo, S	1
Bjondahl, K; Isomaa, B; Nieminen, L	1
Gautieri, RF; Mitala, JJ	1
Johnson, FN	2
Darby, FJ; Grundy, RK	1
Imai, Y; Siekevitz, P	1
Kawai, N; Yamamoto, C	1
Nakazawa, K	1
Pavlovec, A; Petermann, ML	1
Gillen, HW; Pippinger, CE	1
Duff, WM; Grinnell, EH; Kramár, JL; Lydon, TE	1
Cote, IL; Wilson, WA	1
Macdonald, RL; Schulz, DW	1
Jolicoeur, FB; Merkel, AD; Rondeau, DB; Wayner, MJ	1
Heyer, EJ; Macdonald, RL	1
McDevitt, JT; Yunger, LM	1
Castelli, L; Longhi, R; Magno, F; Paccanelli, S; Riva, E; Rottoli, A	1
Clark, JD; Hatch, RC; Jain, AV; Weiss, R	1
Bergelson, S; Daniel, V; Pinkus, R	1
Center, SA; Garland, S; Shaw, N; Trepanier, LA	1
Donevan, SD; Rho, JM; Rogawski, MA	1
Nirodi, CS; Padmanaban, G; Prabhu, L; Ram, N; Sultana, S	1
Fukura, H; Igarashi, M; Kitani, Y; Komiya, Y	1
HARRISON, MS; NAFTALIN, L	1
DUNDAS, JB	1
HAVA, M; KARGEROVA, A; SOBEK, V; WAITZOVA, D	1
Rahman, M; Wang, MD; Zhu, D	1
Brumback, AC; Dzhala, VI; Staley, KJ	1
Fisher, KV; Leydon, C; Lodewyck-Falciglia, D	1
Augustine, G; Bacskai, BJ; Dzhala, VI; Feng, G; Glykys, J; Kuchibhotla, KV; Kuner, T; Staley, KJ	1
Dzhala, V; Staley, KJ	1
Kasalitsa, ChL	1
Ernster, L; Gustafsson, JA; Hrycay, EG; Ingelman-Sundberg, M	1
Gandolfi, AJ; Van Dyke, RA	1
DeAngelo, AB; Garrett, CT; Irwin, D; Queral, AE	1
Cucinell, SA; Dayton, PG; Perel, JM; Weiss, M	1
Stewart, JT; Wilkin, RE	1
Carlson, GP; Fuller, GC	1
Zung, WW	1
Mandel, HG; Riis, M	1
Brodie, BB; Cho, AK; Krishna, G; Reid, WD	1
Mazel, P; Shargel, L	1
Van Dyke, RA; Wineman, CG	1
Kupfer, D; Levin, E	1
Jenkins, LJ; Murphy, SD; Trabulus, MJ	1
Doctor, BP; Kullberg, MP; McGowan, FJ; Miller, WL	1
Fiserova-Bergerova, V	1
Berman, ML; Bochantin, J; Hagler, K; Lowe, HJ	1
Kiese, M; Lenk, W	2
Van Dyke, RA; Wood, CL	1
Baker, JC; Fuller, RW; Molloy, BB; Perry, KW	1
Daly, J; Oesch, F	1
Hansch, C; Martin, YC	1
Anderson, RC; Gibson, WR; Griffing, WJ; Hoffman, DG; Owen, NV	1
Bansal, SK; Gurtoo, HL; Kalin, J; Kari, P; Love, J; Marinello, AJ; Montgomery, JA; Struck, RF	1
Bolos-Sy, AM; Covey, DF; Ferrendelli, JA; Mathews, GC; Rothman, SM	1
Li, TK; Lumeng, L; McBride, WJ; Thielen, RJ	1
GOODMAN, LS; MIYAHARA, JT; SWINYARD, EA	1
HIRAKI, K; HYODO, K	1
KLEMPAU, I; KORANSKY, W; PORTIG, J; VOHLAND, HW	1

Reviews

2 review(s) available for phenobarbital and chlorine

Article	Year
Drugs and taste aversion. Neuroscience and biobehavioral reviews, 1981,Summer, Volume: 5, Issue:2 Topics: Animals; Avoidance Learning; Barbital; Barbiturates; Chlordiazepoxide; Chlorides; Chlorpromazine; Hexobarbital; Lithium; Lithium Chloride; Phenobarbital; Psychotropic Drugs; Rats; Taste; X-Rays	1981
M'ENI'ERE'S DISEASE. The Practitioner, 1963, Volume: 191 Topics: Chlorides; Cochlear Nerve; Diagnosis; Diuretics; Meniere Disease; Neurosurgery; Phenobarbital; Physiology; Potassium; Procaine; Prognosis; Scopolamine; Sodium; Surgical Procedures, Operative; Sympathectomy; Ultrasonic Therapy; Vasodilator Agents	1963

Trials

1 trial(s) available for phenobarbital and chlorine

Article	Year
The effect of placebo and drugs on human sleep. Biological psychiatry, 1973, Volume: 6, Issue:1 Topics: Adult; Chlorine; Electroencephalography; Electromyography; Electrooculography; Ethanol; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Organophosphorus Compounds; Phenobarbital; Placebos; Sleep; Sleep, REM	1973

Other Studies

81 other study(ies) available for phenobarbital and chlorine

Article	Year
Anticonvulsant and anesthetic barbiturates: different postsynaptic actions in cultured mammalian neurons. Neurology, 1979, Volume: 29, Issue:4 Topics: Animals; Barbiturates; Chlorides; Culture Techniques; gamma-Aminobutyric Acid; Glutamates; Ion Channels; Membrane Potentials; Mephobarbital; Mice; Neural Inhibition; Neurons; Pentobarbital; Phenobarbital; Secobarbital; Spinal Cord; Synapses; Synaptic Transmission	1979
Epileptic-type convulsions and magnesium deficiency. Aviation, space, and environmental medicine, 1979, Volume: 50, Issue:7 Topics: Acclimatization; Adult; Chlorides; Epilepsy; Hot Temperature; Humans; Magnesium; Magnesium Deficiency; Male; Phenobarbital; Physical Exertion; Seizures	1979
The effect of lead on aminopyrine N-demethylation. Research communications in chemical pathology and pharmacology, 1979, Volume: 25, Issue:2 Topics: Acetates; Administration, Oral; Aminopyrine N-Demethylase; Animals; Chlorides; Injections, Intraperitoneal; Lead; Liver; Male; Nitrates; Phenobarbital; Porphobilinogen Synthase; Rats	1979
Rat liver microsome-mediated N-demethylation and mutagenicity of azoxymethane. Cancer research, 1978, Volume: 38, Issue:12 Topics: Animals; Azo Compounds; Azoxymethane; Benzoflavones; Biotransformation; Chlorides; Cobalt; Diet; Disulfiram; Formaldehyde; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mutagens; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats	1978
Recurrent hyperosmolar nonketotic episodes in a young diabetic. American journal of diseases of children (1960), 1975, Volume: 129, Issue:2 Topics: Blood Glucose; Chlorides; Dehydration; Diabetes Mellitus, Type 1; Diabetic Coma; Female; Glucose; Humans; Infant; Insulin; Lactates; Osmolar Concentration; Phenobarbital; Potassium; Potassium Chloride; Recurrence; Sodium	1975
Effects of lorazepam tolerance and withdrawal on GABAA receptor-operated chloride channels. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2 Topics: Animals; Appetite Depressants; Binding Sites; Brain; Carbolines; Chloride Channels; Chlorides; Diazepam; Drug Interactions; Ethanol; Flunitrazepam; Ion Channels; Lorazepam; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Phenobarbital; Receptors, GABA-A	1992
Barbiturate tolerance: effects on GABA-operated chloride channel function. Brain research, 1992, Aug-21, Volume: 588, Issue:2 Topics: Animals; Anti-Anxiety Agents; Barbiturates; Brain; Chlorides; Diazepam; Ethanol; gamma-Aminobutyric Acid; Ion Channels; Male; Membranes; Mice; Mice, Inbred ICR; Phenobarbital	1992
Effects of phenobarbital and 3-methylcholanthrene pretreatment on the pharmacokinetics and the pharmacodynamics of bumetanide in rats. Biopharmaceutics & drug disposition, 1991, Volume: 12, Issue:4 Topics: Animals; Blood Proteins; Bumetanide; Chlorides; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Gastric Mucosa; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Potassium; Protein Binding; Rats; Rats, Inbred Strains; Sodium	1991
Effects of phenobarbital and 3-methylcholanthrene pretreatment on the pharmacokinetics and pharmacodynamics of furosemide in rats. Journal of pharmaceutical sciences, 1991, Volume: 80, Issue:7 Topics: Animals; Blood Proteins; Chlorides; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Furosemide; Gastric Mucosa; Kidney; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Potassium; Protein Binding; Rats; Rats, Inbred Strains; Sodium; Tissue Distribution	1991
Zinc increases EGF-stimulated DNA synthesis in primary mouse hepatocytes. Studies in tumor promoter-treated cell cultures. Biochemical pharmacology, 1990, Feb-01, Volume: 39, Issue:3 Topics: Animals; Carcinogens; Cell Division; Cells, Cultured; Chlorides; Culture Media; DNA; Drug Interactions; Epidermal Growth Factor; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Polychlorinated Biphenyls; Tetradecanoylphorbol Acetate; Zinc; Zinc Compounds	1990
Possible involvement of low and high affinity GABA receptors in the chloride influx into synaptosomes. Revista espanola de fisiologia, 1986, Volume: 42, Issue:1 Topics: 4-Aminobutyrate Transaminase; Aldehyde Oxidoreductases; Animals; Chlorides; Diazepam; gamma-Aminobutyric Acid; Ion Channels; Muscimol; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, GABA-A; Synaptosomes	1986
Effects of TMB-8, a calcium antagonist, on transport properties of the isolated canine tracheal epithelium. Biochimica et biophysica acta, 1987, Dec-11, Volume: 905, Issue:2 Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biological Transport; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Chlorides; Colforsin; Dinoprost; Dinoprostone; Dogs; Epithelium; Gallic Acid; Phenobarbital; Prostaglandins E; Prostaglandins F; Sodium; Trachea	1987
Genetic selection for benzodiazepine ataxia produces functional changes in the gamma-aminobutyric acid receptor chloride channel complex. Brain research, 1988, Jun-14, Volume: 452, Issue:1-2 Topics: Animals; Ataxia; Chlorides; Diazepam; Ethanol; Flunitrazepam; Ion Channels; Isoxazoles; Mice; Muscimol; Phenobarbital; Receptors, GABA-A; Time Factors	1988
Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital. Annals of neurology, 1989, Volume: 25, Issue:3 Topics: Animals; Cells, Cultured; Chlorides; Diazepam; Ion Channels; Membrane Potentials; Mice; Phenobarbital; Receptors, GABA-A; Spinal Cord	1989
Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture. The Journal of physiology, 1989, Volume: 417 Topics: Animals; Cells, Cultured; Chlorides; Electrophysiology; Ion Channels; Mice; Neurons; Pentobarbital; Phenobarbital; Receptors, GABA-A; Spinal Cord	1989
Acute and chronic intoxication with carbromal preparations. Journal of toxicology. Clinical toxicology, 1985, Volume: 23, Issue:4-6 Topics: Acute Disease; Bromides; Chlorides; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Chronic Disease; Gastric Juice; Humans; Phenobarbital; Urea	1985
Effect of phenobarbital on acute toxicity and liver damage induced by cerium chloride in male mice. Annales medicinae experimentalis et biologiae Fenniae, 1973, Volume: 51, Issue:2 Topics: Animals; Cerium; Chemical and Drug Induced Liver Injury; Chlorides; Depression, Chemical; Liver; Male; Mice; Phenobarbital; Staining and Labeling; Time Factors	1973
The influence of magnesium and some other divalent cations on hepatic microsomal drug metabolism in vitro. Biochemical pharmacology, 1970, Volume: 19, Issue:2 Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Calcium; Chlorides; Cobalt; Copper; Cytochromes; Edetic Acid; Hexobarbital; In Vitro Techniques; Iron; Magnesium; Male; Manganese; Microsomes, Liver; NADP; Nitrophenols; Phenobarbital; Potassium; Rats; Strontium; Sulfates; Zinc; Zoxazolamine	1970
On the inhibitory action of mersalyl on microsomal drug oxidation: a rigid organization of the electron transport chain. Archives of biochemistry and biophysics, 1971, Volume: 143, Issue:1 Topics: Animals; Carbon Monoxide; Chlorides; Cytochromes; Dealkylation; Electron Transport; Fasting; Formaldehyde; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Magnesium; Male; Mercury; Microsomes, Liver; Morphinans; NAD; NADP; Organomercury Compounds; Osmolar Concentration; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Phenobarbital; Phosphates; Polarography; Potassium Chloride; Rats; Spectrophotometry; Time Factors; Tromethamine; Ultracentrifugation	1971
Evidence for the participation of cytochrome b 5 in hepatic microsomal mixed-function oxidation reactions. Archives of biochemistry and biophysics, 1971, Volume: 143, Issue:1 Topics: Aldehydes; Anaerobiosis; Animals; Chlorides; Colorimetry; Cytochromes; Electron Transport; Formaldehyde; Isocitrate Dehydrogenase; Kinetics; Lipid Metabolism; Magnesium; Male; Malonates; Microsomes, Liver; Models, Biological; Morphinans; Myocardium; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Phenobarbital; Rats; Spectrophotometry; Tromethamine	1971
The role of microsomes in the hepatic metabolism of ethanol. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Acetates; Adenine Nucleotides; Aerobiosis; Amino Alcohols; Anaerobiosis; Animals; Azides; Bile Acids and Salts; Carbon Monoxide; Catalase; Cell Fractionation; Chlorides; Chloromercuribenzoates; Copper; Cyanides; Diet; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Female; Hot Temperature; Hydrogen Peroxide; Iron; Liver; Mercury; Microsomes, Liver; NAD; NADP; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Sulfides; Triazoles	1971
Renal salt and water excretion in the budgerygah (Melopsittacus undulatus). Comparative biochemistry and physiology. A, Comparative physiology, 1972, Volume: 41, Issue:3 Topics: Anesthesia, General; Animals; Body Weight; Chlorides; Female; Glomerular Filtration Rate; Inulin; Kidney; Male; Osmolar Concentration; Phenobarbital; Photometry; Potassium; Potentiometry; Psittaciformes; Sodium; Ureter; Water Deprivation; Water-Electrolyte Balance	1972
Acute hepatic injury by vinyl chloride in rats pretreated with phenobarbital. Nature, 1974, Dec-20, Volume: 252, Issue:5485 Topics: Alanine Transaminase; Alcohol Oxidoreductases; Animals; Chlorides; Dose-Response Relationship, Drug; Drug Synergism; Liver; Male; Phenobarbital; Rats; Sorbitol; Vinyl Compounds	1974
Effect of treatment with phenobarbital and spironolactone on 144Ce levels in blood, liver, urine and faeces at various time periods. Biochemical pharmacology, 1974, May-15, Volume: 23, Issue:10 Topics: Animals; Cerium; Cerium Isotopes; Chlorides; Feces; Female; Liver; Male; Mice; Mice, Inbred Strains; Organ Size; Phenobarbital; Radioisotopes; Sex Factors; Spironolactone; Time Factors	1974
Apparent enzyme inhibition through enzyme-induction studies as a possible mode of action of certain cobalt compounds. Journal of pharmaceutical sciences, 1971, Volume: 60, Issue:12 Topics: Animals; Chlorides; Cobalt; Enzyme Induction; Enzyme Inhibitors; Female; Hexobarbital; Mice; Nitrites; Phenobarbital; Sleep; Zoxazolamine	1971
Dissociation of vertical and horizontal components of activity in rats treated with lithium chloride. Experientia, 1972, May-15, Volume: 28, Issue:5 Topics: Animals; Behavior, Animal; Chlorides; Lithium; Locomotion; Movement; Phenobarbital; Placebos; Rats; Rats, Inbred Strains	1972
Glutathione S-aryltransferase: the effect of treating male and female rats with phenobarbitone on the apparent kinetic parameters for the conjugation of 1,2-dichloro-4-nitrobenzene and 1-chloro-2,4-dinitrobenzene with glutathione. The Biochemical journal, 1972, Volume: 128, Issue:1 Topics: Animals; Chlorides; Female; Glutathione; Kinetics; Liver; Male; Nitrobenzenes; Phenobarbital; Rats; Sex Factors; Transferases	1972
A comparison of some properties of microsomal cytochrome P-450 from normal, methylcholanthrene-, and phenobarbital-treated rats. Archives of biochemistry and biophysics, 1971, Volume: 144, Issue:1 Topics: 1-Propanol; Amines; Animals; Chemical Phenomena; Chemistry; Chlorides; Cycloheximide; Cytochromes; Fasting; Fatty Alcohols; Heme; Hydrogen-Ion Concentration; Kinetics; Male; Mathematics; Mercury; Methylcholanthrene; Microsomes, Liver; Nitriles; Oxidation-Reduction; Phenobarbital; Potassium; Protein Biosynthesis; Rats; Spectrophotometry; Sulfites; Thiocyanates; Triazoles	1971
Generation of the seizure discharge in thin sections from the guinea pig brain in chloride-free medium in vitro. The Japanese journal of physiology, 1968, Oct-15, Volume: 18, Issue:5 Topics: Animals; Chlorides; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; Phenobarbital; Seizures; Telencephalon	1968
Studies on the demethylation, hydroxylation and N-oxidation of imipramine in rat liver. Biochemical pharmacology, 1970, Volume: 19, Issue:4 Topics: Amino Alcohols; Animals; Carbon Isotopes; Chlorides; Chromatography, Paper; Dealkylation; Desipramine; Ethylamines; Imipramine; Liver; Magnesium; Male; Metabolism; Methylation; Oxidation-Reduction; Oxides; Phenobarbital; Proadifen; Rats; Valerates	1970
Dissociation of rat liver ribosomes to active subunits by urea. Biochemistry, 1971, Jul-06, Volume: 10, Issue:14 Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Cell Fractionation; Centrifugation, Density Gradient; Chemical Precipitation; Chlorides; Chromatography, Gel; Liver; Macromolecular Substances; Magnesium; Male; Microsomes, Liver; Phenobarbital; Phenylalanine; Polynucleotides; Protein Biosynthesis; Rats; Ribonucleases; Ribosomes; Sulfhydryl Compounds; Ultracentrifugation; Uracil Nucleotides; Urea	1971
Low specific gravity syndrome. Clinical chemistry, 1968, Volume: 14, Issue:5 Topics: Adult; Anticonvulsants; Calcium; Chlorides; Chronic Disease; Creatinine; Epilepsy; Female; Humans; Intellectual Disability; Male; Mass Screening; Metabolic Clearance Rate; Middle Aged; Osmolar Concentration; Phenobarbital; Phenytoin; Potassium; Sodium; Specific Gravity; Time Factors; Urea; Urine; Vasopressins; Water-Electrolyte Balance	1968
Further studies on the diuretic activity of antidiuretic hormone. Endocrinology, 1968, Volume: 83, Issue:2 Topics: Animals; Arginine; Chlorides; Diuresis; Dogs; Female; Pentobarbital; Phenobarbital; Thiopental; Vasopressins	1968
Effects of barbiturates on inhibitory and excitatory responses to applied neurotransmitters in Aplysia. The Journal of pharmacology and experimental therapeutics, 1980, Volume: 214, Issue:1 Topics: Acetylcholine; Action Potentials; Animals; Aplysia; Barbiturates; Chlorides; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; In Vitro Techniques; Neural Inhibition; Neurons; Neurotransmitter Agents; Pentobarbital; Phenobarbital; Potassium; Sodium	1980
Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions. Brain research, 1981, Mar-23, Volume: 209, Issue:1 Topics: Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; Evoked Potentials; gamma-Aminobutyric Acid; Ion Channels; Mice; Neural Inhibition; Neurons; Pentobarbital; Phenobarbital; Spinal Cord	1981
Barbiturate reduction of calcium-dependent action potentials: correlation with anesthetic action. Brain research, 1982, Mar-18, Volume: 236, Issue:1 Topics: Animals; Barbiturates; Calcium; Chlorides; Culture Techniques; Ion Channels; Membrane Potentials; Mice; Nociceptors; Pentobarbital; Phenobarbital; Sodium; Synapses; Synaptic Transmission	1982
Rotation induced by intranigral phenobarbital: evidence of barbiturate GABAergic activity. Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:5 Topics: Animals; Binding Sites; Chlorides; Ion Channels; Male; Motor Activity; Phenobarbital; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Rotation; Substantia Nigra	1982
Psychoactive drugs and stimulus analysis: VI. Evaluation of one-trial modification of exploration as a basis for psychoactive drug classification. The International journal of neuroscience, 1983, Volume: 20, Issue:1-2 Topics: Animals; Arousal; Chlordiazepoxide; Chlorides; Chlorpromazine; Discrimination Learning; Exploratory Behavior; Lithium; Lithium Chloride; Phenobarbital; Psychotropic Drugs; Rats; Social Environment; Tranylcypromine	1983
[Changes in water-salt metabolism during chronic treatment with phenobarbital]. Minerva pediatrica, 1984, Aug-31, Volume: 36, Issue:15-16 Topics: Child; Child, Preschool; Chlorides; Humans; Osmolar Concentration; Phenobarbital; Potassium; Sodium; Time Factors; Water-Electrolyte Balance	1984
Effect of enzyme inducers and inhibitors and glutathione precursor and depleter on induced acute aflatoxicosis in rabbits. American journal of veterinary research, 1982, Volume: 43, Issue:6 Topics: Acute Disease; Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; Carcinogens; Chlorides; Cobalt; Cysteine; Enzyme Induction; Enzyme Inhibitors; Glutathione; Goats; Liver; Male; Maleates; Microsomes, Liver; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Rabbits; Rats; Stanozolol	1982
Induction of AP-1 (Fos/Jun) by chemical agents mediates activation of glutathione S-transferase and quinone reductase gene expression. Oncogene, 1994, Volume: 9, Issue:2 Topics: Arsenates; Arsenites; Base Sequence; Binding Sites; Carcinoma, Embryonal; Carcinoma, Hepatocellular; Chlorides; Cycloheximide; Gene Expression Regulation; Genes, fos; Genes, jun; Genes, Regulator; Glutathione Transferase; Humans; Hydrocarbons; Hydrogen Peroxide; Molecular Sequence Data; Phenobarbital; Phorbol Esters; Proto-Oncogene Proteins c-jun; Quinone Reductases; RNA, Messenger; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured; Zinc Compounds	1994
High dietary chloride content associated with loss of therapeutic serum bromide concentrations in an epileptic dog. Journal of the American Veterinary Medical Association, 1996, Jan-15, Volume: 208, Issue:2 Topics: Animals; Anticonvulsants; Bromides; Chlorides; Diet; Dog Diseases; Dogs; Epilepsy; Female; Liver; Phenobarbital; Potassium Compounds	1996
Direct activation of GABAA receptors by barbiturates in cultured rat hippocampal neurons. The Journal of physiology, 1996, Dec-01, Volume: 497 ( Pt 2) Topics: Animals; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Electrophysiology; Female; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Hippocampus; Kinetics; Neurons; Pentobarbital; Phenobarbital; Picrotoxin; Pregnancy; Prohibitins; Rats; Rats, Sprague-Dawley; Time Factors	1996
A 65-kDa protein mediates the positive role of heme in regulating the transcription of CYP2B1/B2 gene in rat liver. The Journal of biological chemistry, 1997, Apr-04, Volume: 272, Issue:14 Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorides; Cobalt; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ferric Compounds; Gene Expression Regulation, Enzymologic; Heme; Hemin; Liver; Molecular Weight; Nuclear Proteins; Phenobarbital; Protoporphyrins; Rats; RNA, Messenger; Steroid Hydroxylases; Transcription, Genetic	1997
GABA(A) receptor in growth cones: the outline of GABA(A) receptor-dependent signaling in growth cones is applicable to a variety of alpha-subunit species. Journal of neuroscience research, 1999, Nov-01, Volume: 58, Issue:3 Topics: Aging; Animals; Animals, Newborn; Calcium; Cerebral Cortex; Chlorides; Diazepam; Fetus; gamma-Aminobutyric Acid; Neurons; Phenobarbital; Propofol; Prosencephalon; Protein Isoforms; Rats; Rats, Wistar; Receptors, GABA-A; Signal Transduction; Synaptic Membranes	1999
LOWE'S SYNDROME. Proceedings of the Royal Society of Medicine, 1964, Volume: 57 Topics: Acidosis; Albuminuria; Alkalies; Anti-Bacterial Agents; Blood; Bone Diseases; Calcium; Cataract; Child; Chlorides; Chronic Kidney Disease-Mineral and Bone Disorder; Genetics, Medical; Glaucoma; Humans; Intellectual Disability; Nystagmus, Pathologic; Phenobarbital; Renal Aminoacidurias; Rickets; Urinary Tract Infections; Vitamin D	1964
STUDIES ON DETOXIFICATION OF NEOMYCIN. Toxicology and applied pharmacology, 1965, Volume: 7 Topics: Calcium Chloride; Central Nervous System; Cerebral Ventricles; Chlorides; Desoxycorticosterone; Dihydrotachysterol; Ergocalciferols; Hydrocortisone; Magnesium; Mice; Neomycin; Neostigmine; Paralysis; Pharmacology; Phenobarbital; Potassium; Potassium Chloride; Pupil; Research; Respiratory System; Salivation; Spasm; Toxicology	1965
Protons inhibit Cl- conductance by direct or allosteric interaction with the GABA-binding site in the rat recombinant alpha1beta2gamma2L and alpha1beta2 GABAA receptor. European journal of pharmacology, 2005, Dec-28, Volume: 528, Issue:1-3 Topics: Allosteric Regulation; Animals; Bicuculline; Chlorides; Dose-Response Relationship, Drug; GABA Antagonists; GABA Modulators; gamma-Aminobutyric Acid; Hydrogen-Ion Concentration; Ion Channel Gating; Membrane Potentials; Oocytes; Phenobarbital; Protons; Rats; Receptors, GABA-A; Recombinant Proteins; Transfection; Xenopus laevis	2005
Bumetanide enhances phenobarbital efficacy in a neonatal seizure model. Annals of neurology, 2008, Volume: 63, Issue:2 Topics: Animals; Anticonvulsants; Bumetanide; Chloride Channels; Chlorides; Drug Synergism; Drug Therapy, Combination; Epilepsy, Benign Neonatal; Hippocampus; Ion Transport; Magnesium Deficiency; Male; Membrane Potentials; Models, Biological; Neural Inhibition; Organ Culture Techniques; Patch-Clamp Techniques; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Solute Carrier Family 12, Member 2	2008
The cystic fibrosis transmembrane conductance regulator and chloride-dependent ion fluxes of ovine vocal fold epithelium. Journal of speech, language, and hearing research : JSLHR, 2009, Volume: 52, Issue:3 Topics: 1-Methyl-3-isobutylxanthine; Amiloride; Analysis of Variance; Animals; Calcium Channel Blockers; Cell Membrane; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Excitatory Amino Acid Antagonists; Immunohistochemistry; Ion Transport; Laryngeal Mucosa; Microscopy, Electron, Transmission; ortho-Aminobenzoates; Patch-Clamp Techniques; Phenobarbital; Sheep; Sodium Channel Blockers; Uridine Triphosphate; Vocal Cords	2009
Differences in cortical versus subcortical GABAergic signaling: a candidate mechanism of electroclinical uncoupling of neonatal seizures. Neuron, 2009, Sep-10, Volume: 63, Issue:5 Topics: Amygdala; Animals; Animals, Newborn; Anticonvulsants; Bumetanide; Chlorides; Female; gamma-Aminobutyric Acid; In Vitro Techniques; Male; Neocortex; Neurons; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Seizures; Sex Characteristics; Sodium Potassium Chloride Symporter Inhibitors; Solute Carrier Family 12, Member 2; Synaptic Transmission; Thalamus	2009
Acute and chronic efficacy of bumetanide in an in vitro model of posttraumatic epileptogenesis. CNS neuroscience & therapeutics, 2015, Volume: 21, Issue:2 Topics: Action Potentials; Analysis of Variance; Animals; Anticonvulsants; Bumetanide; Chlorides; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Organ Culture Techniques; Phenobarbital; Receptors, Immunologic; Recombinant Fusion Proteins; Sodium Potassium Chloride Symporter Inhibitors; Time Factors	2015
[Pterofen in the treatment of hypertensive disease]. Klinicheskaia meditsina, 1976, Volume: 54, Issue:1 Topics: Adrenergic alpha-Antagonists; Benzimidazoles; Chlorine; Diuretics; Drug Combinations; Humans; Hypertension; Phenobarbital; Sodium; Triamterene	1976
Sodium periodate, sodium chloride, organic hydroperoxides, and H2O2 as hydroxylating agents in steroid hydroxylation reactions catalyzed by partially purified cytochrome P-450. Biochemical and biophysical research communications, 1975, Sep-02, Volume: 66, Issue:1 Topics: Androstenedione; Animals; Chlorine; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Kinetics; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Periodic Acid; Peroxides; Phenobarbital; Rats; Steroid Hydroxylases	1975
Characteristics of a microsomal dechlorination system. Molecular pharmacology, 1975, Volume: 11, Issue:6 Topics: Animals; Chlorine; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Kinetics; Lung; Male; Microsomes; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Organ Specificity; Phenobarbital; Rats	1975
Phosphorylation of specific rat plasma membrane proteins during promotion of gamma-glutamyl transpeptidase-positive hepatic foci and inhibition by di(2-ethylhexyl)phthalate. Cancer research, 1985, Volume: 45, Issue:6 Topics: Animals; Chlorine; Diethylhexyl Phthalate; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Membrane Proteins; Molecular Weight; Phenobarbital; Phosphorylation; Phthalic Acids; Precancerous Conditions; Prohibitins; Protein Kinases; Rats; Rats, Inbred Strains	1985
Dose-dependence of drug plasma level decline in dogs. The Journal of pharmacology and experimental therapeutics, 1967, Volume: 158, Issue:2 Topics: Acetates; Animals; Barbiturates; Blood Proteins; Chlorine; Chromatography, Thin Layer; Dicumarol; Dogs; Kinetics; Liver; Muscles; Phenobarbital; Phenylbutazone; Phenytoin; Proadifen; Probenecid; Receptors, Drug; Vitamin K	1967
Determination of sulfonamides and local anesthetics with 9=chloroacridine by quenching fluorometry. Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:3 Topics: 4-Aminobenzoic Acid; Acridines; Aminobenzoates; Anesthetics, Local; Aspirin; Benzocaine; Chlorine; Chlorpromazine; Ephedrine; Fluorescence; Methods; Oxazepam; Phenobarbital; Spectrometry, Fluorescence; Sulfamethizole; Sulfamethoxypyridazine; Sulfanilamides; Sulfathiazoles; Sulfisoxazole; Sulfonamides; Tetracycline	1972
Interaction of modifiers of hepatic microsomal drug metabolism and the inhalation toxicity of 1,1-dichloroethylene. Research communications in chemical pathology and pharmacology, 1972, Volume: 4, Issue:3 Topics: Aerosols; Alanine Transaminase; Animals; Aspartate Aminotransferases; Chlorine; Chromatography, Gas; Drug Interactions; Ethylamines; Glucose-6-Phosphatase; Hydrocarbons, Halogenated; Lung; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Phenobarbital; Proadifen; Rats; Time Factors	1972
Interference of barbiturates with pyrimidine incorporation. II. Structural specificity of the inhibition of orotate uptake in Bacillus cereus. Biochemical pharmacology, 1970, Volume: 19, Issue:6 Topics: Amobarbital; Bacillus cereus; Barbiturates; Bemegride; Biological Transport; Carbon Isotopes; Carboxylic Acids; Central Nervous System Stimulants; Chemical Phenomena; Chemistry; Chemistry, Physical; Chlorine; Chlorpromazine; Glutethimide; Hexobarbital; Hydantoins; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Orotic Acid; Pentobarbital; Phenobarbital; Phenytoin; Primidone; Solubility; Succinimides; Thiopental; Thymine; Trimethadione; Tromethamine; Uracil; Urea	1970
Drug metabolism in man: past, present, and future. Annals of the New York Academy of Sciences, 1971, Jul-06, Volume: 179 Topics: Aerobiosis; Alkylating Agents; Allyl Compounds; Animals; Autoradiography; Bromine; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chlorine; Chromatography, Paper; Ethers, Cyclic; Glutathione; Hydrocarbons, Halogenated; Iodine; Liver; Male; Mice; Microsomes, Liver; Models, Biological; NADP; Necrosis; Phenobarbital; Rats; Sheep; Sulfur Isotopes	1971
Influence of 2,4-dichloro-6-phenoxyethyl-amine (DPEA) and -diethylaminoethyl diphenylpropylacetate (SKF-525A) on hepatic microsomal azoreductase activity from phenobarbital or 3-methylcholanthrene induced rats. Biochemical pharmacology, 1972, Volume: 21, Issue:1 Topics: Animals; Azo Compounds; Carbon Monoxide; Chlorine; Cytochromes; Enzyme Activation; Enzyme Induction; Ethylamines; Flavin Mononucleotide; Male; Methylcholanthrene; Microsomes, Liver; NADP; Naphthalenes; Nitrogen; Oxidoreductases; Phenobarbital; Phenols; Proadifen; Rats; Rats, Inbred Strains; Sulfonamides; Sulfonic Acids	1972
Enzymatic dechlorination. Dechlorination of chloroethanes and propanes in vitro. Biochemical pharmacology, 1971, Volume: 20, Issue:2 Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlorine; Enzyme Induction; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Radioisotopes; Rats; Ultracentrifugation	1971
Monooxygenase drug metabolizing activity in CaCl 2 -aggregated hepatic microsomes from rat liver. Biochemical and biophysical research communications, 1972, May-12, Volume: 47, Issue:3 Topics: Aminopyrine; Aniline Compounds; Animals; Calcium Chloride; Carbon Monoxide; Chlorine; Dronabinol; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats	1972
Biochemical effects of 1,1-dichloroethylene in rats: comparison with carbon tetrachloride and 1,2-dichloroethylene. Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3 Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Carbon Tetrachloride; Chlorine; Ethylenes; Glucose-6-Phosphatase; Hydrocarbons, Halogenated; Lethal Dose 50; Liver; Phenobarbital; Rats; Structure-Activity Relationship; Time Factors; Tyrosine Transaminase	1972
Studies in the single extraction of amphetamine and phenobarbital from urine using XAD-2 resin. Biochemical medicine, 1973, Volume: 7, Issue:2 Topics: Acetates; Amphetamine; Butanols; Carbon Isotopes; Chlorine; Chloroform; Humans; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; Hydrolysis; Ion Exchange Resins; Male; Methods; Morphine; Phenobarbital; Solvents	1973
Changes of fluoride content in bone: an index of drug defluorination in vivo. Anesthesiology, 1973, Volume: 38, Issue:4 Topics: Anesthetics; Animals; Biotransformation; Body Weight; Bone and Bones; Chlorine; Drug Interactions; Ethanol; Ethers; Female; Fluoridation; Fluorides; Fluorine; Furans; Halothane; Hydrocarbons, Halogenated; Lethal Dose 50; Male; Methoxyflurane; Methyl Ethers; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Pregnancy; Proadifen; Rats; Time Factors	1973
Uptake and elimination of methoxyflurane as influenced by enzyme induction in the rat. Anesthesiology, 1973, Volume: 38, Issue:4 Topics: Anesthesia, Inhalation; Animals; Chlorine; Drug Interactions; Enzyme Induction; Fluorides; Kidney; Liver; Male; Methoxyflurane; Microsomes, Liver; Phenobarbital; Proadifen; Radioisotopes; Rats; Time Factors	1973
Omega- and (omega-1)-hydroxylation of 4-chloropropionanilide in liver microsomes of rabbits treated with phenobarbital or 3-methylcholanthrene. Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20 Topics: Acetophenones; Anilides; Animals; Carbon Monoxide; Chlorine; Drug Storage; Female; Hydroxylation; Hypoxia; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pressure; Propionates; Rabbits; Time Factors	1973
Metabolism of methoxyflurane: release of inorganic fluoride in human and rat hepatic microsomes. Anesthesiology, 1973, Volume: 39, Issue:6 Topics: Animals; Biotransformation; Chlorine; Enzyme Induction; Fluorides; Formaldehyde; Humans; Hydrogen-Ion Concentration; Male; Methoxyflurane; Methylcholanthrene; Microsomes, Liver; Nitrous Oxide; Phenobarbital; Rats; Tetracycline	1973
Omega- and (omega-1)-hydroxylation of 4-chloropropionanilide by rabbits and rabbit liver microsomes. Biochemical pharmacology, 1973, Oct-15, Volume: 22, Issue:20 Topics: Acrylates; Anilides; Animals; Benzene Derivatives; Chlorine; Chromatography, Thin Layer; Ethanol; Glycolates; Hydroxylation; In Vitro Techniques; Isomerism; Lactates; Magnetic Resonance Spectroscopy; Mandelic Acids; Methylcholanthrene; Microsomes, Liver; Optical Rotation; Optical Rotatory Dispersion; Phenobarbital; Propionates; Rabbits; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Stereoisomerism	1973
Effect of phenobarbital on the metabolism and serotonin-depleting action of 4-chloro-beta, beta-difluoroamphetamine in rats. Archives internationales de pharmacodynamie et de therapie, 1974, Volume: 208, Issue:2 Topics: Adipose Tissue; Amphetamine; Animals; Brain; Brain Chemistry; Chlorine; Depression, Chemical; Enzyme Induction; Epididymis; Fluorine; Half-Life; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Serotonin; Serotonin Antagonists; Time Factors	1974
Conversion of naphthalene to trans-naphthalene dihydrodiol: evidence for the presence of a coupled aryl monooxygenase-epoxide hydrase system in hepatic microsomes. Biochemical and biophysical research communications, 1972, Feb-25, Volume: 46, Issue:4 Topics: Animals; Carbon Isotopes; Chemical Phenomena; Chemistry; Chlorine; Ethers, Cyclic; Ethylmaleimide; Glutathione; Glycols; Guinea Pigs; Hydrolases; Male; Maleates; Methylcholanthrene; Microsomes, Liver; Naphthalenes; Oxygenases; Phenanthrenes; Phenobarbital	1972
Influence of hydrophobic character on the relative rate of oxidation of drugs by rat liver microsomes. Journal of medicinal chemistry, 1971, Volume: 14, Issue:9 Topics: Aniline Compounds; Animals; Barbiturates; Caffeine; Chemical Phenomena; Chemistry, Physical; Chlorine; Codeine; Ephedrine; Fatty Alcohols; Hexobarbital; Kinetics; Male; Mathematics; Microsomes, Liver; Mixed Function Oxygenases; Naphthalenes; Oxidoreductases; Phenobarbital; Physostigmine; Rats; Solubility; Structure-Activity Relationship	1971
Effects of dietary administration of 5-(3,4-dichloro-phenyl)-5-ethylbarbituric acid (dichlorophenobarbital) to rats: emphasis on hepatic drug-metabolizing enzymes and morphology. Toxicology and applied pharmacology, 1971, Volume: 18, Issue:3 Topics: Animals; Anisoles; Barbiturates; Body Weight; Chlorine; Dealkylation; Enzyme Induction; Female; Hepatomegaly; Liver; Male; Microscopy, Electron; Microsomes, Liver; Nitro Compounds; Organ Size; Phenobarbital; Rats; Stimulation, Chemical; Thyroid Gland	1971
Metabolism of cyclophosphamide by purified cytochrome P-450 from microsomes of phenobarbital-treated rats. Biochemical and biophysical research communications, 1984, Apr-30, Volume: 120, Issue:2 Topics: Animals; Carbon Radioisotopes; Chemical Phenomena; Chemistry; Chlorine; Cyclophosphamide; Cytochrome P-450 Enzyme System; Microsomes, Liver; Phenobarbital; Rats; Sulfur Oxides; Tritium	1984
Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors. Neuropharmacology, 1996, Volume: 35, Issue:2 Topics: 4-Butyrolactone; Animals; Anticonvulsants; Binding Sites; Cells, Cultured; Chlordiazepoxide; Chlorine; Dose-Response Relationship, Drug; GABA Modulators; gamma-Aminobutyric Acid; Hippocampus; Patch-Clamp Techniques; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Transfection	1996
GABA(A) receptor function in the cerebral cortex of alcohol-naive P and NP rats. Pharmacology, biochemistry, and behavior, 1998, Volume: 59, Issue:1 Topics: Animals; Cerebral Cortex; Chlorine; Choice Behavior; Drug Synergism; Ethanol; gamma-Aminobutyric Acid; Male; Pentobarbital; Phenobarbital; Radioisotopes; Rats; Receptors, GABA-A	1998
Effect of chlorination on the anticonvulsant activity of phenobarbital. Journal of pharmaceutical sciences, 1963, Volume: 52 Topics: Anticonvulsants; Chlorine; Halogenation; Humans; Ions; Phenobarbital	1963
[ON POISONING WITH ORGANIC CHLORINE AGRICULTURAL PREPARATIONS--BASIC AND CLINICAL ASPECTS OF THE -DRIN PREPARATIONS]. [Chiryo] [Therapy], 1964, Volume: 46 Topics: Chlorine; Dieldrin; Insecticides; Ions; Organic Agriculture; Pentobarbital; Phenobarbital; Physiology; Poisoning; Toxicology	1964
[THE ELIMINATION OF ALPHA- AND GAMMA-HEXACHLOROCYCLOHEXANE AND ITS ALTERATION BY ENZYMES OF LIVER MICROSOMES]. Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1964, Apr-09, Volume: 247 Topics: Chlorine; Feces; Hexachlorocyclohexane; Injections, Intraperitoneal; Liver; Metabolism; Microsomes; Microsomes, Liver; Pharmacology; Phenobarbital; Radioisotopes; Radionuclide Imaging; Rats; Research; Urine	1964