phenobarbital and chlordecone

phenobarbital has been researched along with chlordecone in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199018 (64.29)18.7374
1990's9 (32.14)18.2507
2000's1 (3.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Couture, J; Dahlström-King, L; Plaa, GL1
Faroon, OM; Kodavanti, PR; Kodavanti, UP; Mehendale, HM1
Teo, S; Vore, M1
Cai, ZW; Mehendale, HM1
Kodavanti, PR; Kodavanti, UP; Mehendale, HM1
Cai, Z; Mehendale, HM1
Andersen, ME; Gargas, ML; Mehendale, HM; Thakore, KN1
Guzelian, PS; Kocarek, TA; Schuetz, EG2
Bell, AN; Mehendale, HM1
Crouch, LS; Ebel, RE2
McLamb, RL; Shaw, S; Tilson, HA1
Klingensmith, JS; Mehendale, HM3
Lockard, VG; Mehendale, HM; Purushotham, KR2
Blanke, RV; Fitzgerald, R; Guzelian, PS; Sirica, AE; Wilkerson, CS; Wu, LL1
Loft, S; Poulsen, HE; Schou, JS; Tvede, KG1
Hodgson, E; Levi, P; Lewandowski, M1
Davis, ME; Mehendale, HM1
Aldous, CN; Chetty, CS; Desaiah, D1
Klingensmith, JS; Lockard, V; Mehendale, HM1
Agarwal, AK; Mehendale, HM2
Ebel, RE; McGrath, EA1

Other Studies

28 other study(ies) available for phenobarbital and chlordecone

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Influence of agents affecting monooxygenase activity on taurolithocholic acid-induced cholestasis.
    Toxicology letters, 1992, Volume: 63, Issue:3

    Topics: Animals; Bile; Body Weight; Chlordecone; Cholestasis; Cobalt; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Synergism; Enzyme Induction; Ketones; Liver; Male; Methylcholanthrene; Mirex; Organ Size; Phenobarbital; Piperonyl Butoxide; Proadifen; Rats; Rats, Sprague-Dawley; Taurolithocholic Acid

1992
Pivotal role of hepatocellular regeneration in the ultimate hepatotoxicity of CCl4 in chlordecone-, mirex-, or phenobarbital-pretreated rats.
    Toxicologic pathology, 1992, Volume: 20, Issue:4

    Topics: Animals; Autoradiography; Carbon Tetrachloride; Cell Size; Chemical and Drug Induced Liver Injury; Chlordecone; DNA; Drug Synergism; Liver; Liver Diseases; Liver Regeneration; Male; Mirex; Mitosis; Phenobarbital; Rats; Rats, Sprague-Dawley; Thymidine; Time Factors; Tritium

1992
Mirex exposure inhibits the uptake of estradiol-17 beta(beta-D-glucuronide), taurocholate, and L-alanine into isolated rat hepatocytes.
    Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3

    Topics: Adenosine Triphosphatases; Alanine; Animals; Cells, Cultured; Chlordecone; Dose-Response Relationship, Drug; Estradiol; Female; In Vitro Techniques; Insecticides; Ion Channels; Liver; Magnesium; Mirex; Phenobarbital; Potassium; Rats; Rats, Inbred Strains; Sodium; Taurocholic Acid

1990
Lethal effects of CCl4 and its metabolism by Mongolian gerbils pretreated with chlordecone, phenobarbital, or mirex.
    Toxicology and applied pharmacology, 1990, Volume: 104, Issue:3

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Dioxide; Carbon Tetrachloride; Chlordecone; Cytochrome P-450 Enzyme System; Gerbillinae; Insecticides; Lethal Dose 50; Lipid Peroxidation; Liver; Male; Mirex; Phenobarbital

1990
Altered hepatic energy status in chlordecone (Kepone)-potentiated CCl4 hepatotoxicity.
    Biochemical pharmacology, 1990, Aug-15, Volume: 40, Issue:4

    Topics: Adenosine Triphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Carbon Tetrachloride; Chlordecone; Energy Metabolism; Insecticides; Lipid Peroxidation; Liver; Male; Mirex; Phenobarbital; Rats; Rats, Inbred Strains

1990
Hepatotoxicity and lethality of halomethanes in Mongolian gerbils pretreated with chlordecone, phenobarbital or mirex.
    Archives of toxicology, 1991, Volume: 65, Issue:3

    Topics: Animals; Bromotrichloromethane; Carbon Tetrachloride; Chlordecone; Chloroform; DNA; Dose-Response Relationship, Drug; Gerbillinae; Lethal Dose 50; Liver; Male; Mirex; Phenobarbital; Species Specificity

1991
PB-PK derived metabolic constants, hepatotoxicity, and lethality of BrCCl3 in rats pretreated with chlordecone, phenobarbital, or mirex.
    Toxicology and applied pharmacology, 1991, Volume: 109, Issue:3

    Topics: Administration, Inhalation; Administration, Oral; Animals; Atmosphere Exposure Chambers; Bromotrichloromethane; Chlordecone; Drug Synergism; Liver; Male; Mirex; Phenobarbital; Rats; Rats, Inbred Strains

1991
Selective induction of cytochrome P450e by kepone (chlordecone) in primary cultures of adult rat hepatocytes.
    Molecular pharmacology, 1991, Volume: 40, Issue:2

    Topics: Animals; Cells, Cultured; Chlordecone; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Liver; Male; Mirex; Phenobarbital; Rats; Rats, Inbred Strains; RNA, Messenger

1991
Comparative changes in hepatic DNA, RNA, protein, lipid, and glycogen induced by a subtoxic dose of CCl4 in chlordecone, mirex, and phenobarbital pretreated rats.
    Toxicology letters, 1987, Volume: 35, Issue:2-3

    Topics: Animals; Carbon Tetrachloride; Chlordecone; DNA; Insecticides; Lipids; Liver; Liver Glycogen; Male; Mirex; Phenobarbital; Proteins; Rats; Rats, Inbred Strains; RNA

1987
Influence of chlordecone and mirex exposure on benzo[a]pyrene metabolism of rat-liver microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:1

    Topics: Animals; Benzo(a)pyrene; Benzoflavones; Biotransformation; Chlordecone; Cytochrome P-450 Enzyme System; Epoxide Hydrolases; Insecticides; Liver; Methylcholanthrene; Microsomes, Liver; Mirex; Pesticide Residues; Phenobarbital; Rats; Subcellular Fractions

1987
The effects of lindane, DDT, and chlordecone on avoidance responding and seizure activity.
    Toxicology and applied pharmacology, 1987, Mar-30, Volume: 88, Issue:1

    Topics: Animals; Avoidance Learning; Chlordecone; Chlordiazepoxide; DDT; Dose-Response Relationship, Drug; Hexachlorocyclohexane; Insecticides; Learning; Male; Memory; Phenobarbital; Phenytoin; Rats; Rats, Inbred F344; Seizures

1987
Benzo[a]pyrene metabolism in the Mongolian gerbil: influence of chlordecone and mirex induction.
    Xenobiotica; the fate of foreign compounds in biological systems, 1987, Volume: 17, Issue:7

    Topics: Animals; Benzo(a)pyrene; Benzopyrene Hydroxylase; Chlordecone; Cytochrome P-450 Enzyme System; Gerbillinae; Insecticides; Male; Methylcholanthrene; Microsomes, Liver; Mirex; Phenobarbital

1987
In vivo metabolism of CCl4 by rats pretreated with chlordecone, mirex, or phenobarbital.
    Toxicology and applied pharmacology, 1988, Volume: 93, Issue:2

    Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Carbon Tetrachloride; Chlordecone; Cytochrome P-450 Enzyme System; Drug Synergism; Insecticides; Lipid Peroxides; Liver; Male; Mirex; Phenobarbital; Rats; Rats, Inbred Strains; Transaminases

1988
Amplification of chloroform hepatotoxicity and lethality by dietary chlordecone (kepone) in mice.
    Toxicologic pathology, 1988, Volume: 16, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Body Weight; Chlordecone; Chloroform; Drug Synergism; Insecticides; Lethal Dose 50; Liver; Male; Mice; Mice, Inbred Strains; Mirex; Organ Size; Phenobarbital

1988
Evaluation of chlordecone in a two-stage model of hepatocarcinogenesis: a significant sex difference in the hepatocellular carcinoma incidence.
    Carcinogenesis, 1989, Volume: 10, Issue:6

    Topics: Animals; Chlordecone; Diethylnitrosamine; Female; gamma-Glutamyltransferase; Hepatectomy; Insecticides; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains; Reference Values; Sex Factors

1989
The time course of liver injury and [3H]thymidine incorporation in chlordecone-potentiated CHCl3 hepatotoxicity.
    Experimental and molecular pathology, 1989, Volume: 51, Issue:1

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cell Nucleus; Chemical and Drug Induced Liver Injury; Chlordecone; Chloroform; DNA; Drug Synergism; Insecticides; Mice; Mirex; Phenobarbital; Time Factors

1989
Methyl parathion toxicity in rats is changed by pretreatment with the pesticides chlordecone, mirex and linuron.
    Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement, 1989, Volume: 13

    Topics: Acetylcholinesterase; Animals; Brain; Chlordecone; Herbicides; Insecticides; Linuron; Male; Methyl Parathion; Mirex; Parathion; Phenobarbital; Rats; Rats, Inbred Strains

1989
Induction of cytochrome P-450 isozymes by mirex and chlordecone.
    Journal of biochemical toxicology, 1989,Fall, Volume: 4, Issue:3

    Topics: Animals; Chlordecone; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Immunoblotting; In Vitro Techniques; Insecticides; Isoenzymes; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mirex; Mixed Function Oxygenases; Organ Size; Phenobarbital

1989
Functional and biochemical correlates of chlordecone exposure and its enhancement of CCl4 hepatotoxicity.
    Toxicology, 1980, Volume: 15, Issue:2

    Topics: Animals; Bile; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; Drug Interactions; Enzyme Induction; Glutathione; Insecticides; Kidney; Lipid Metabolism; Lipid Peroxides; Liver; Liver Function Tests; Male; Mixed Function Oxygenases; Pentobarbital; Phenobarbital; Protein Binding; Rats; Sleep; Time Factors

1980
Potentiation of CCl4 lethality by chlordecone.
    Toxicology letters, 1982, Volume: 11, Issue:1-2

    Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Chlordecone; Drug Synergism; Insecticides; Lethal Dose 50; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1982
Alterations in tissue distribution of chlordecone (kepone) in the rat following phenobarbital or SKF-525A administration.
    Journal of toxicology and environmental health, 1983, Volume: 11, Issue:3

    Topics: Animals; Chlordecone; Drug Synergism; Insecticides; Liver; Male; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Tissue Distribution

1983
Acute hepatotoxicity and lethality of CCl4 in chlordecone-pretreated rats.
    Experimental and molecular pathology, 1983, Volume: 39, Issue:1

    Topics: Acute Disease; Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chlordecone; Insecticides; Isocitrate Dehydrogenase; Lethal Dose 50; Liver; Male; Mirex; Phenobarbital; Rats; Rats, Inbred Strains

1983
Destruction of hepatic mixed-function oxygenase parameters by CCl4 in rats following acute treatment with chlordecone, Mirex, and phenobarbital.
    Life sciences, 1983, Dec-05, Volume: 33, Issue:23

    Topics: Alanine Transaminase; Aminopyrine N-Demethylase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chlordecone; Cytochrome P-450 Enzyme System; Drug Synergism; Glucose-6-Phosphatase; Insecticides; Isocitrate Dehydrogenase; Male; Microsomes, Liver; Mirex; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1983
CCl4-induced alterations in Ca++ homeostasis in chlordecone and phenobarbital pretreated animals.
    Life sciences, 1984, Jan-09, Volume: 34, Issue:2

    Topics: Animals; Calcium; Carbon Tetrachloride; Chlordecone; Cytochrome P-450 Enzyme System; Insecticides; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Rats; Rats, Inbred Strains

1984
CCl4-hepatotoxicity in the Mongolian gerbil: influence of monooxygenase system induction.
    Toxicology letters, 1984, Volume: 22, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Chlordecone; Cytochrome b Group; Cytochromes b5; Enzyme Induction; Gerbillinae; Liver; Male; Mirex; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Phenobarbital

1984
Perturbation of calcium homeostasis by CCl4 in rats pretreated with chlordecone and phenobarbital.
    Environmental health perspectives, 1984, Volume: 57

    Topics: Animals; Calcium; Carbon Tetrachloride; Chlordecone; Cytochrome P-450 Enzyme System; Cytosol; Diet; Drug Synergism; Homeostasis; Insecticides; Male; Microsomes, Liver; Mitochondria, Liver; Phenobarbital; Rats; Rats, Inbred Strains

1984
Regulation of cytochrome P450 2B1/2 mRNAs by Kepone (chlordecone) and potent estrogens in primary cultures of adult rat hepatocytes on Matrigel.
    Toxicology letters, 1994, Volume: 71, Issue:2

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Cells, Cultured; Chloral Hydrate; Chlordecone; Cytochrome P-450 Enzyme System; Diethylstilbestrol; Estradiol; Estrogens; Ethinyl Estradiol; Female; Liver; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; RNA, Messenger; Steroid Hydroxylases

1994