phenobarbital has been researched along with chloramphenicol in 90 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 62 (68.89) | 18.7374 |
1990's | 9 (10.00) | 18.2507 |
2000's | 13 (14.44) | 29.6817 |
2010's | 6 (6.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Strassburg, CP; Tukey, RH | 1 |
Duffy, EM; Jorgensen, WL | 1 |
Topliss, JG; Yoshida, F | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Fujita, H | 1 |
Raw, I; Rockwell, P | 1 |
Bloxham, RA; Durbin, GM; Johnson, T; Winterborn, MH | 1 |
Hammond, KB | 1 |
Rylance, GW | 1 |
Krishna, G; Pohl, LR; Reddy, GB | 1 |
Cooper, MB; Craft, JA; Estall, MR; Rabin, BR | 1 |
Weiss, H | 1 |
Bruck, E; Colburn, WA; Gibaldi, M; Hilligoss, DM; Koup, JR; McNamara, P | 1 |
Bock, KW; Remmer, H; Rexer, B | 1 |
Pringsheim, W; Windorfer, A | 1 |
Adams, HR; Isaacson, EL; Masters, BS | 1 |
Irinoda, Y; Kitada, K; Maezawa, S; Oira, S; Watanabe, K | 2 |
Grace, R; Kelley, VC; Lemire, RJ; Mackler, B; Shepard, TH; Tippit, DF | 1 |
Carlos García, R; Quintana Loyola, A; Rodríguez Sasiain, JM; Santafé Oroz, J; Segarra Doménech, J | 1 |
Tefuarani, N; Vince, JD | 1 |
Hirota, Y | 1 |
Bence, J; Kurcz, M; Szabó, I; Vas, A | 1 |
Halpert, JR; Sipes, IG; Smith, BJ; Stevens, JC | 1 |
Amouzadeh, HR; Nossaman, BC; Sangiah, S | 1 |
Ciaccio, PJ; Halpert, JR | 1 |
Buchanan, N | 1 |
Liu, RL; Wang, J; Yan, SQ; Zhu, XY | 1 |
Gorsky, LD; Halpert, JR; Miller, NE | 1 |
Bonitenko, IuIu; Buchko, VM; Kalmanson, ML | 1 |
Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET | 1 |
Kutt, H; Penry, JK | 1 |
Watanabe, A | 1 |
Bock, KW; Fröhling, W; Remmer, H; Rexer, B | 1 |
Ganshorn, A; Kurz, H | 1 |
Lange, G | 1 |
Bonanomi, L; Gazzaniga, A; Stramentinoli, G | 1 |
Despopoulos, A; Palmer, DL; Rael, ED | 1 |
Kröner, H; Schlag, P; Staib, W | 1 |
Della Bella, D; Gazzaniga, A; Remmer, H; Stramentinoli, G | 1 |
Allen, JR; Chesney, CF; Hsu, IC | 1 |
Nichol, AW | 1 |
Windorfer, A | 1 |
Allen, JR; Chesney, CF; Frazee, WJ | 1 |
Di Stefano, F; Gatto, A; Patanè, S | 1 |
Prabhu, VG | 1 |
Weingärtner, L | 1 |
Calderoni, FJ; Mitoma, C; Neubauer, SE; Tagg, JS; Tanabe, M; Yasuda, D | 1 |
Bella, DD; Bonanomi, L; Ferrari, V; Marca, G | 1 |
Alterthum, K; Bauer, P; Stünkel, S; Windorfer, A | 1 |
Duwe, K; Kuhnz, W; Nau, H; Wittfoht, W | 1 |
Betnér, I; Halpert, J; Näslund, B | 1 |
de Louvois, J; Hurley, R; Mulhall, A | 1 |
Boyd, MR | 1 |
Chiba, K; Ishizaki, T; Kushida, K | 1 |
Zenk, KE | 1 |
Béraud, M; Delmas, C; Derache, P | 1 |
Batnitzky, S; Lansky, L; Morantz, RA | 1 |
Durrell, DC; Glazer, JP; Hilty, MD; Nahata, MC; Powell, DA | 1 |
Jones, DH; Kim, HL | 1 |
Halpert, J; Neal, RA | 1 |
Jähnchen, E; Schmidt, W; Trenk, D | 1 |
Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW | 1 |
Hattori, T; Hayashi, Y; Horio, F; Machino, S; Makino, S; Shibata, T; Yoshida, A | 1 |
Lee, MG; Lee, SH | 1 |
Choi, YJ; Kim, WB; Kwon, JW; Lee, HJ; Lee, MG; Yang, J | 1 |
Emerole, GO; Farombi, EO; Nwankwo, JO; Odutola, B; Wara, SH | 1 |
Koie, H; Kurotobi, EN; Sakai, T | 1 |
BAKER, L; KAHN, SB; LISCHNER, H; WILLIAMS, WJ | 1 |
GOODALL, P; HARRISON, GA; ROSEN, M | 1 |
DUNDON, S; HOLLAND, PD | 1 |
VANZWANENBERG, D | 1 |
BOX, QT | 1 |
HEINONEN, J | 1 |
BURNS, JJ; CONNEY, AH | 1 |
Anuka, JA; Ejiofor, JI; Kwanashie, HO | 1 |
Batt, AM; Boutin, JA; Jacquier, A; Marlière, P; Siest, G | 1 |
7 review(s) available for phenobarbital and chloramphenicol
Article | Year |
---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Humans; Immunoassay; Infant; Infant, Newborn; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Quality Control; Spectrophotometry; Sulfonamides; Theophylline | 1977 |
Therapeutic drug monitoring in childhood.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbamazepine; Child; Chloramphenicol; Digoxin; Drug Interactions; Half-Life; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Saliva; Theophylline; Valproic Acid | 1986 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline | 1981 |
THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM.
Topics: Aminopyrine; Chloramphenicol; Coumarins; Dicumarol; Humans; Metabolism; Pharmaceutical Preparations; Pharmacology; Phenacetin; Phenobarbital; Phenylbutazone | 1964 |
83 other study(ies) available for phenobarbital and chloramphenicol
Article | Year |
---|---|
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics | 2012 |
Anticancer agents and glutathione--from the standpoint of their pharmacokinetics.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Bleomycin; Carbon Tetrachloride; Chloramphenicol; Cyclophosphamide; Drug Interactions; Drug Synergism; Glutathione; Humans; Mitomycins; Phenobarbital | 1977 |
Effect of a single dose of inducers and inhibitors on the rate of synthesis of cytochromes and reductases in liver organelles.
Topics: Aflatoxins; Animals; Chloramphenicol; Cycloheximide; Cytochrome Reductases; Cytochromes; Dactinomycin; Female; Liver; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; Phenobarbital; Polychlorinated Biphenyls; Rabbits | 1979 |
Chloramphenicol and phenobarbitone--a drug interaction.
Topics: Chloramphenicol; Drug Interactions; Female; Haemophilus influenzae; Humans; Infant; Male; Meningitis, Haemophilus; Phenobarbital | 1979 |
Chloramphenicol and phenobarbitone--a drug interaction.
Topics: Child; Chloramphenicol; Drug Interactions; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Phenobarbital | 1979 |
A new pathway of metabolism of chloramphenicol which influences the interpretation of its irreversible binding to protein in vivo.
Topics: Animals; Blood Proteins; Chemical Phenomena; Chemistry; Chloramphenicol; Glycine; Hydrolysis; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Serine; Tissue Distribution | 1979 |
The biosynthesis of cytochrome P450 by heavy and light rough endoplasmic reticulum of rat liver.
Topics: Animals; Chloramphenicol; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Kinetics; Liver; Male; Phenobarbital; Rats | 1979 |
[Dependence of the crystal growth of solids on the intensity of size reduction on the example of various pharmaceutical agents. 2].
Topics: Chloramphenicol; Crystallization; Pharmaceutical Preparations; Phenobarbital; Pilocarpine; Prednisolone; Temperature | 1977 |
Interaction of chloramphenicol with phenytoin and phenobarbital. Case report.
Topics: Adult; Chloramphenicol; Drug Interactions; Humans; Kinetics; Male; Phenobarbital; Phenytoin | 1978 |
Relationship between microsomal hydroxylase and glucuronyltransferase.
Topics: Aminopyrine; Animals; Bilirubin; Biotransformation; Chloramphenicol; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Female; Glucuronosyltransferase; Hexosyltransferases; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Naphthols; Nitrophenols; Phenobarbital; Polyethylene Glycols; Rats; Sex Factors; Sonication | 1975 |
Studies on the concentrations of chloramphenicol in the serum and cerebrospinal fluid of neonates, infants, and small children. Reciprocal reactions between chloramphenicol, penicillin and phenobarbitone.
Topics: Age Factors; Child, Preschool; Chloramphenicol; Drug Interactions; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Meningitis; Penicillins; Phenobarbital | 1977 |
Inhibition of hepatic microsomal enzymes by chloramphenicol.
Topics: Animals; Benzphetamine; Chloramphenicol; Cytochrome P-450 Enzyme System; Drug Interactions; Ethylmorphine-N-Demethylase; Hexobarbital; In Vitro Techniques; Male; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pentobarbital; Phenobarbital | 1977 |
Combined cancer chemotherapy with cyclophoshamide and an inducer of microsomal drug-metabolizing enzymes (cytochrome P-450) in tumor-bearing rats.
Topics: Animals; Chloramphenicol; Cyclophosphamide; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Male; Microsomes; Neoplasms, Experimental; Phenobarbital; Rats; Sarcoma, Yoshida | 1975 |
Studies of the development of congenital anomalies in rats. III. Effects of inhibition of mitochondrial energy systems on embryonic development.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Chloramphenicol; Diet; Embryo Implantation; Energy Metabolism; Enzyme Inhibitors; Female; Fetus; Malonates; Mitochondria; Phenobarbital; Phenytoin; Pregnancy; Propylene Glycols; Rats; Teratogens | 1975 |
[Acute tolerance and time changes in ketamine-induced sleep under the effect of phenobarbital and chlorophenicol. Experimental study].
Topics: Anesthesia; Animals; Chloramphenicol; Ketamine; Male; Phenobarbital; Preanesthetic Medication; Rats; Sleep; Time Factors | 1976 |
Purulent meningitis in children: outcome using a standard management regimen with chloramphenicol.
Topics: Bacteria; Child; Child, Preschool; Chloramphenicol; Humans; Infant; Infant, Newborn; Meningitis, Bacterial; Phenobarbital; Prospective Studies; Seizures; Treatment Outcome | 1992 |
[Hemopoietic disorder caused by drugs--special significance placed on anemia].
Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Chloramphenicol; Ethanol; Humans; Methotrexate; Methyldopa; Middle Aged; Neomycin; Penicillins; Phenacetin; Phenobarbital | 1991 |
Neonatal treatment with phenobarbital, zixoryn and chloramphenicol lack of imprinting effect of zixoryn on microsomal enzyme activities.
Topics: Animals; Animals, Newborn; Benzhydryl Compounds; Chloramphenicol; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1990 |
The biochemical basis for the species difference in hepatic microsomal 4-vinylcyclohexene epoxidation between female mice and rats.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chloramphenicol; Cyclohexanes; Cyclohexenes; Cytochrome P-450 Enzyme System; Female; Hydroxylation; Mice; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Species Specificity; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Testosterone | 1990 |
Effects of chloramphenicol, cimetidine and phenobarbital on and tolerance to xylazine-ketamine anesthesia in dogs.
Topics: Anesthesia; Animals; Behavior, Animal; Chloramphenicol; Cimetidine; Consciousness; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Ketamine; Male; Phenobarbital; Reflex; Thiazines; Xylazine | 1990 |
Characterization of a phenobarbital-inducible dog liver cytochrome P450 structurally related to rat and human enzymes of the P450IIIA (steroid-inducible) gene subfamily.
Topics: Amino Acid Sequence; Animals; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Enzyme Induction; Immunoblotting; Immunoglobulin G; Kinetics; Male; Microsomes, Liver; Molecular Sequence Data; Molecular Weight; NADP; Phenobarbital; Rats; Spectrophotometry; Steroid Hydroxylases; Troleandomycin | 1989 |
[First pass effect of gallanilide in rats].
Topics: Animals; Anti-Arrhythmia Agents; Carbon Tetrachloride Poisoning; Chloramphenicol; Drug Incompatibility; Female; Gallic Acid; Lidocaine; Male; Phenobarbital; Rats; Ventricular Fibrillation | 1988 |
On the mechanism of the inactivation of the major phenobarbital-inducible isozyme of rat liver cytochrome P-450 by chloramphenicol.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzphetamine; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Kinetics; Male; NADPH-Ferrihemoprotein Reductase; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry; Time Factors | 1985 |
[Use of levomycetin in acute 1,2-dichloroethane poisonings].
Topics: Acute Disease; Animals; Chloramphenicol; Drug Evaluation; Drug Evaluation, Preclinical; Ethylene Dichlorides; Humans; Hydrocarbons, Chlorinated; Male; Mice; Middle Aged; Phenobarbital; Rats; Time Factors | 1985 |
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin | 1985 |
Effect of chronic administration of centrally acting compounds on chloramphenicol metabolism in schizophrenic patients.
Topics: Adult; Antipsychotic Agents; Chloramphenicol; Chronic Disease; Female; Glucuronates; Half-Life; Humans; Injections, Intravenous; Liver Cirrhosis; Male; Middle Aged; Nitro Compounds; Phenobarbital; Phenothiazines; Schizophrenia | 1974 |
Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.
Topics: Ammonium Sulfate; Animals; Bilirubin; Chemical Precipitation; Chloramphenicol; Cycloheximide; Deoxycholic Acid; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Hexosyltransferases; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Naphthols; Nitrophenols; Phenobarbital; Rats; Structure-Activity Relationship; Surface-Active Agents; Trypsin | 1973 |
[Differences between the protein binding of newborns and adults and their importance for pharmacological action].
Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental | 1968 |
[Differential induction of microsomal N- and p-hydroxylation of aniline and N-ethylamiline in rabbits].
Topics: Anesthetics, Local; Aniline Compounds; Animals; Chloramphenicol; Dactinomycin; Enzyme Induction; Ethionine; Female; Hydroxylamines; Liver; Male; Microsomes; Mixed Function Oxygenases; NADP; Phenobarbital; Phenols; Rabbits | 1967 |
Increased antitumor activity of cyclophosphamide (Endoxan) following pretreatment with inducer of drug-metabolizing enzymes (cytochrome P-450).
Topics: Alkylation; Animals; Chloramphenicol; Cyclophosphamide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes; Drug Interactions; Enzyme Induction; Male; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry | 1974 |
[Glucuroconjugation in vitro of chloramphenicol in normal rats and in rats pre-treated with phenobarbital].
Topics: Animals; Biopharmaceutics; Biotransformation; Chloramphenicol; Glucuronates; Male; Phenobarbital; Rats | 1974 |
Induction of chloramphenicol metabolism by phenobarbital.
Topics: Animals; Chloramphenicol; Dogs; Enzyme Induction; Half-Life; In Vitro Techniques; Microsomes, Liver; Perfusion; Phenobarbital; Rats | 1972 |
[Studies concerning the relationship between the release of enzymes and electrolyte shift in the liver (author's transl)].
Topics: Alanine Transaminase; Animals; Calcium; Carbon Tetrachloride Poisoning; Chloramphenicol; Dinitrophenols; Extracellular Space; Female; Hydrocortisone; L-Lactate Dehydrogenase; Liver; Liver Diseases; Phenobarbital; Potassium; Rats; Sodium | 1974 |
Increase of chloramphenicol glucuronidation in rats treated with phenobarbital.
Topics: Administration, Oral; Animals; Chloramphenicol; Glucuronates; Glucuronidase; Half-Life; Hydrolysis; Injections, Intravenous; Liver; Male; Oxidation-Reduction; Phenobarbital; Rats; Stimulation, Chemical; Time Factors | 1974 |
Modifications of the in vitro metabolism of the hepatotoxic pyrrolizidine alkaloid, monocrotaline.
Topics: Animals; Biotransformation; Chloramphenicol; In Vitro Techniques; Male; Microsomes, Liver; Oxides; Phenobarbital; Proadifen; Pyrrolizidine Alkaloids; Rats | 1974 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
[Dangers and potential uses of enzyme stimulating medication on newborns and infants].
Topics: Aminopyrine; Chloramphenicol; Drug Synergism; Enzyme Induction; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice, Neonatal; Liver; Phenobarbital; Pregnancy; Stimulation, Chemical | 1972 |
Modifications of pyrrolizidine alkaloid intoxication resulting from altered hepatic microsomal enzymes.
Topics: Animals; Chloramphenicol; Dose-Response Relationship, Drug; Drug Interactions; Injections, Subcutaneous; Lung; Male; Microsomes, Liver; Myocardium; Pentobarbital; Phenobarbital; Poisoning; Pyrrolizidine Alkaloids; Rats; Sleep | 1972 |
Non-equivalent preparations of the same drug.
Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin | 1971 |
[Drug interactions during therapy. Blood levels of chloramphenicol in animals pretreated with luminal as an enzyme inductor].
Topics: Animals; Chloramphenicol; Drug Interactions; Enzyme Induction; Phenobarbital; Rabbits | 1971 |
Effect of chronic treatment with therapeutically useful antibiotics on the response of certain pharmacologic agents in the rat.
Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Chlordan; Chlortetracycline; Dactinomycin; Drug Antagonism; Drug Tolerance; Enzyme Induction; Enzymes; Hexobarbital; Male; Oxytetracycline; Penicillins; Phenobarbital; Rats; Sleep; Streptomycin | 1970 |
[Special pharmacological problems of the neonatal period from the clinical point of view].
Topics: Ampicillin; Animals; Chloramphenicol; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Extracellular Space; Female; Humans; Infant, Newborn; Kidney; Liver; Maternal-Fetal Exchange; Oxytetracycline; Pharmaceutical Preparations; Phenobarbital; Pregnancy; Streptomycin; Sulfonamides | 1969 |
Effects of various chemical agents on drug metabolism and cholesterol biosynthesis.
Topics: Acetanilides; Acetates; Aminopyrine; Animals; Anticholesteremic Agents; Benzopyrenes; Carbon Isotopes; Chloramphenicol; Cholesterol; Depression, Chemical; Drug Synergism; Ethers; Ethylamines; Hexobarbital; Insecticides; Iproniazid; Liver; Male; Mevalonic Acid; Microsomes; Nitrophenols; Phenobarbital; Proadifen; Rabbits; Rats; Sleep; Time Factors | 1968 |
Chloramphenicol metabolism in the phenobarbital-induced rat. Comparison with thiamphenicol.
Topics: Acetates; Animals; Chloramphenicol; Glucuronates; Male; Phenobarbital; Pneumococcal Infections; Rats; Statistics as Topic | 1968 |
[Effects of drug interaction in infancy (author's transl)].
Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid | 1980 |
Microscale ultrafiltration technique for determining free drug in 50-microL serum samples.
Topics: Animals; Chloramphenicol; Diazepam; Furosemide; Humans; Indomethacin; Infant; Infant, Newborn; Microchemistry; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ultrafiltration; Valproic Acid | 1984 |
Suicide inactivation of rat liver cytochrome P-450 by chloramphenicol in vivo and in vitro.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzene Derivatives; Chloramphenicol; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Iodobenzoates; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
The pharmacokinetics of chloramphenicol in the neonate and young infant.
Topics: Administration, Oral; Aging; Chloramphenicol; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Penicillins; Phenobarbital | 1983 |
Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues.
Topics: Animals; Biotransformation; Bromobenzenes; Chloramphenicol; Furans; Humans; Liver; Lung; Methylcholanthrene; Microsomes; Models, Biological; Monocrotaline; Pharmaceutical Preparations; Phenobarbital; Pyrrolizidine Alkaloids; Terpenes | 1980 |
Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.
Topics: Adult; Anticonvulsants; Carbamazepine; Chloramphenicol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1983 |
[Effects of chloramphenicol on microsomal reductases associated with lipoperoxidation (author's transl)].
Topics: Animals; Chloramphenicol; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Triglycerides | 1982 |
Non-operative management of pseudotumor cerebri caused by lateral sinus thrombosis.
Topics: Child; Chloramphenicol; Dexamethasone; Female; Glycerol; Humans; Papilledema; Phenobarbital; Pseudotumor Cerebri; Sinus Thrombosis, Intracranial | 1980 |
Interactions among chloramphenicol, phenytoin, and phenobarbital in a pediatric patient.
Topics: Child; Chloramphenicol; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Postoperative Complications | 1981 |
Toxicity of hymenoxon in Swiss white mice following pretreatment with microsomal enzyme inducers, inhibitors and carbon tetrachloride.
Topics: Animals; Aroclors; Carbon Tetrachloride; Chloramphenicol; Chlorodiphenyl (54% Chlorine); Drug Interactions; Enzyme Induction; In Vitro Techniques; Lethal Dose 50; Liver; Mice; Microsomes, Liver; Phenobarbital; Sesquiterpenes | 1981 |
Inactivation of purified rat liver cytochrome P-450 by chloramphenicol.
Topics: Amino Acids; Animals; Carbon Monoxide; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; NADP; Phenobarbital; Rats | 1980 |
Effect of induction and inhibition of drug metabolism on pharmacokinetics and anticoagulant activity of the enantiomers of phenprocoumon in rats.
Topics: 4-Hydroxycoumarins; Animals; Anticoagulants; Chloramphenicol; Enzyme Induction; Kinetics; Liver; Male; Phenobarbital; Phenprocoumon; Prothrombin Time; Rats | 1980 |
Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity.
Topics: Aminopyrine; Animals; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Induction; Free Radical Scavengers; Ketoconazole; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley | 1994 |
UDP glucuronosyltransferase gene expression is involved in the stimulation of ascorbic acid biosynthesis by xenobiotics in rats.
Topics: Analysis of Variance; Animals; Ascorbic Acid; Base Sequence; Blotting, Northern; Body Weight; Chloramphenicol; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Injections, Intraperitoneal; Liver; Methylcholanthrene; Molecular Sequence Data; Nitrophenols; Organ Size; Phenobarbital; Polymerase Chain Reaction; Rats; Rats, Gunn; Rats, Inbred Strains; RNA, Messenger; Time Factors; Xenobiotics | 1993 |
Effect of phenobarbital, 3-methylcholanthrene, and chloramphenicol pretreatment on the pharmacokinetics and pharmacodynamics of azosemide in rats.
Topics: Animals; Area Under Curve; Blood Proteins; Chloramphenicol; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diuretics; Enzyme Induction; Enzyme Inhibitors; Half-Life; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Sulfanilamides | 1997 |
Pharmacokinetic changes of M1, M2, M3 and M4 after intravenous administration of a new anthracycline, DA-125, to rats pretreated with phenobarbital, 3-methylcholanthrene, chloramphenicol, or SKF-525A.
Topics: Animals; Anthracyclines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antineoplastic Agents; Carcinogens; Carotid Arteries; Chloramphenicol; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Injections, Intravenous; Jugular Veins; Male; Methylcholanthrene; Phenobarbital; Proadifen; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley | 1998 |
Chloramphenicol and ampicillin-induced changes in rat hepatic esterase and amidase activities.
Topics: Amidohydrolases; Ampicillin; Animals; Anti-Bacterial Agents; Carboxylic Ester Hydrolases; Chloramphenicol; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Indicators and Reagents; Isoenzymes; Liver; Male; Nitrophenols; Organophosphorus Compounds; Penicillins; Phenobarbital; Protein Synthesis Inhibitors; Proteins; Rats; Rats, Wistar | 2000 |
Double-chambered right ventricle in a dog.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Chloramphenicol; Dog Diseases; Dogs; Echocardiography; Electrocardiography; Enalapril; Encephalitis; Fatal Outcome; Female; Heart Septal Defects, Ventricular; Heart Ventricles; Magnetic Resonance Imaging; Phenobarbital; Prednisolone; Radiography, Thoracic; Seizures; Ventricular Dysfunction, Right | 2000 |
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE INGESTION OF PHENOBARBITAL AND PRIMIDONE. REPORT OF A CASE IN A SIX-YEAR-OLD CHILD.
Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; Barbiturates; Candidiasis, Vulvovaginal; Child; Chloramphenicol; Epilepsy; Esophageal Stenosis; Intellectual Disability; Nitrofurantoin; Periodontal Diseases; Phenobarbital; Primidone; Sulfonamides; Toxicology | 1963 |
HAEMORRHAGIC COMPLICATIONS DURING THE TREATMENT OF TETANUS.
Topics: Amobarbital; Child; Chloramphenicol; Chlorpromazine; Diphenhydramine; Hematuria; Hemolysis; Hydrocortisone; Hypoprothrombinemias; Mephenesin; Meprobamate; Penicillins; Phenobarbital; Promethazine; Purpura; Purpura, Thrombocytopenic; Sulfamethizole; Sulfathiazoles; Tetanus; Tetanus Toxoid; Toxicology; Tracheotomy; Trimeprazine; Tubocurarine; Vitamin K 1 | 1964 |
LISTERIA MONOCYTOGENES MENINGITIS IN THE NEWBORN.
Topics: Chloramphenicol; Clinical Laboratory Techniques; Humans; Infant, Newborn; Infant, Newborn, Diseases; Ireland; Listeria; Meningitis; Meningitis, Listeria; Mice; Penicillins; Phenobarbital; Rabbits; Research; Streptomycin | 1964 |
WHOOPING COUGH; PRESENT TRENDS IN TREATMENT.
Topics: Child; Chloral Hydrate; Chloramphenicol; Humans; Infant; Pertussis Vaccine; Phenobarbital; Pulmonary Atelectasis; Quarantine; Toxicology; Whooping Cough | 1964 |
THE TREATMENT OF TETANUS.
Topics: Adolescent; Child; Chloramphenicol; Humans; Infant; Infant, Newborn; Penicillins; Phenobarbital; Statistics as Topic; Tetanus; Tetanus Antitoxin; Tetanus Toxoid; Texas; Tracheotomy | 1964 |
THE EFFECT OF DRUGS ON THE DURATION OF TOXIC SYMPTOMS CAUSED BY SUBLETHAL DOSES OF LOCAL ANESTHETICS. AN EXPERIMENTAL STUDY ON MICE.
Topics: Anesthetics; Anesthetics, Local; Barbiturates; Bemegride; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Ethionine; Iproniazid; Isoniazid; Lidocaine; Mepivacaine; Meprobamate; Mice; Nikethamide; Pentobarbital; Pharmacology; Phenobarbital; Research; Toxicology | 1964 |
Effect of artemether on pentobarbitone sleep and electrical activity in rats.
Topics: Amphetamine; Animals; Antimalarials; Antipsychotic Agents; Artemether; Artemisinins; Central Nervous System Stimulants; Chloramphenicol; Chlorpromazine; Cortical Synchronization; Dose-Response Relationship, Drug; Electromyography; Female; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Pentobarbital; Phenobarbital; Rats; Rats, Wistar; Reticular Formation; Sleep; Superior Colliculi; Time Factors | 2007 |
UDP-glucuronosyltransferase activities in human liver microsomes and in some laboratory animal species.
Topics: Adolescent; Aged; Animals; Camphanes; Chloramphenicol; Eugenol; Female; Glucuronides; Glucuronosyltransferase; Humans; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Middle Aged; Nitrophenols; Phenobarbital; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Swine; Uridine Diphosphate | 1981 |