phenobarbital and chloramphenicol

phenobarbital has been researched along with chloramphenicol in 90 studies

Research

Studies (90)

TimeframeStudies, this research(%)All Research%
pre-199062 (68.89)18.7374
1990's9 (10.00)18.2507
2000's13 (14.44)29.6817
2010's6 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Fujita, H1
Raw, I; Rockwell, P1
Bloxham, RA; Durbin, GM; Johnson, T; Winterborn, MH1
Hammond, KB1
Rylance, GW1
Krishna, G; Pohl, LR; Reddy, GB1
Cooper, MB; Craft, JA; Estall, MR; Rabin, BR1
Weiss, H1
Bruck, E; Colburn, WA; Gibaldi, M; Hilligoss, DM; Koup, JR; McNamara, P1
Bock, KW; Remmer, H; Rexer, B1
Pringsheim, W; Windorfer, A1
Adams, HR; Isaacson, EL; Masters, BS1
Irinoda, Y; Kitada, K; Maezawa, S; Oira, S; Watanabe, K2
Grace, R; Kelley, VC; Lemire, RJ; Mackler, B; Shepard, TH; Tippit, DF1
Carlos García, R; Quintana Loyola, A; Rodríguez Sasiain, JM; Santafé Oroz, J; Segarra Doménech, J1
Tefuarani, N; Vince, JD1
Hirota, Y1
Bence, J; Kurcz, M; Szabó, I; Vas, A1
Halpert, JR; Sipes, IG; Smith, BJ; Stevens, JC1
Amouzadeh, HR; Nossaman, BC; Sangiah, S1
Ciaccio, PJ; Halpert, JR1
Buchanan, N1
Liu, RL; Wang, J; Yan, SQ; Zhu, XY1
Gorsky, LD; Halpert, JR; Miller, NE1
Bonitenko, IuIu; Buchko, VM; Kalmanson, ML1
Balfour, C; Dunbar, D; Halpert, J; Kaminsky, LS; Miller, NE; Morgan, ET1
Kutt, H; Penry, JK1
Watanabe, A1
Bock, KW; Fröhling, W; Remmer, H; Rexer, B1
Ganshorn, A; Kurz, H1
Lange, G1
Bonanomi, L; Gazzaniga, A; Stramentinoli, G1
Despopoulos, A; Palmer, DL; Rael, ED1
Kröner, H; Schlag, P; Staib, W1
Della Bella, D; Gazzaniga, A; Remmer, H; Stramentinoli, G1
Allen, JR; Chesney, CF; Hsu, IC1
Nichol, AW1
Windorfer, A1
Allen, JR; Chesney, CF; Frazee, WJ1
Di Stefano, F; Gatto, A; Patanè, S1
Prabhu, VG1
Weingärtner, L1
Calderoni, FJ; Mitoma, C; Neubauer, SE; Tagg, JS; Tanabe, M; Yasuda, D1
Bella, DD; Bonanomi, L; Ferrari, V; Marca, G1
Alterthum, K; Bauer, P; Stünkel, S; Windorfer, A1
Duwe, K; Kuhnz, W; Nau, H; Wittfoht, W1
Betnér, I; Halpert, J; Näslund, B1
de Louvois, J; Hurley, R; Mulhall, A1
Boyd, MR1
Chiba, K; Ishizaki, T; Kushida, K1
Zenk, KE1
Béraud, M; Delmas, C; Derache, P1
Batnitzky, S; Lansky, L; Morantz, RA1
Durrell, DC; Glazer, JP; Hilty, MD; Nahata, MC; Powell, DA1
Jones, DH; Kim, HL1
Halpert, J; Neal, RA1
Jähnchen, E; Schmidt, W; Trenk, D1
Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW1
Hattori, T; Hayashi, Y; Horio, F; Machino, S; Makino, S; Shibata, T; Yoshida, A1
Lee, MG; Lee, SH1
Choi, YJ; Kim, WB; Kwon, JW; Lee, HJ; Lee, MG; Yang, J1
Emerole, GO; Farombi, EO; Nwankwo, JO; Odutola, B; Wara, SH1
Koie, H; Kurotobi, EN; Sakai, T1
BAKER, L; KAHN, SB; LISCHNER, H; WILLIAMS, WJ1
GOODALL, P; HARRISON, GA; ROSEN, M1
DUNDON, S; HOLLAND, PD1
VANZWANENBERG, D1
BOX, QT1
HEINONEN, J1
BURNS, JJ; CONNEY, AH1
Anuka, JA; Ejiofor, JI; Kwanashie, HO1
Batt, AM; Boutin, JA; Jacquier, A; Marlière, P; Siest, G1

Reviews

7 review(s) available for phenobarbital and chloramphenicol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drugs and children: methods for therapeutic monitoring.
    Clinical toxicology, 1977, Volume: 10, Issue:2

    Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Humans; Immunoassay; Infant; Infant, Newborn; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Quality Control; Spectrophotometry; Sulfonamides; Theophylline

1977
Therapeutic drug monitoring in childhood.
    Australian paediatric journal, 1986, Volume: 22, Issue:1

    Topics: Aminoglycosides; Anti-Bacterial Agents; Carbamazepine; Child; Chloramphenicol; Digoxin; Drug Interactions; Half-Life; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Saliva; Theophylline; Valproic Acid

1986
Usefulness of blood levels of antiepileptic drugs.
    Archives of neurology, 1974, Volume: 31, Issue:5

    Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines

1974
An overview of perinatal clinical pharmacology.
    Clinics in laboratory medicine, 1981, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline

1981
THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM.
    Seminars in hematology, 1964, Volume: 1

    Topics: Aminopyrine; Chloramphenicol; Coumarins; Dicumarol; Humans; Metabolism; Pharmaceutical Preparations; Pharmacology; Phenacetin; Phenobarbital; Phenylbutazone

1964

Other Studies

83 other study(ies) available for phenobarbital and chloramphenicol

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
    Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1

    Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics

2012
Anticancer agents and glutathione--from the standpoint of their pharmacokinetics.
    Tsurumi shigaku. Tsurumi University dental journal, 1977, Volume: 3, Issue:1

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Bleomycin; Carbon Tetrachloride; Chloramphenicol; Cyclophosphamide; Drug Interactions; Drug Synergism; Glutathione; Humans; Mitomycins; Phenobarbital

1977
Effect of a single dose of inducers and inhibitors on the rate of synthesis of cytochromes and reductases in liver organelles.
    Molecular and cellular biochemistry, 1979, Dec-14, Volume: 28, Issue:1-3

    Topics: Aflatoxins; Animals; Chloramphenicol; Cycloheximide; Cytochrome Reductases; Cytochromes; Dactinomycin; Female; Liver; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; Phenobarbital; Polychlorinated Biphenyls; Rabbits

1979
Chloramphenicol and phenobarbitone--a drug interaction.
    Archives of disease in childhood, 1979, Volume: 54, Issue:1

    Topics: Chloramphenicol; Drug Interactions; Female; Haemophilus influenzae; Humans; Infant; Male; Meningitis, Haemophilus; Phenobarbital

1979
Chloramphenicol and phenobarbitone--a drug interaction.
    Archives of disease in childhood, 1979, Volume: 54, Issue:7

    Topics: Child; Chloramphenicol; Drug Interactions; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Phenobarbital

1979
A new pathway of metabolism of chloramphenicol which influences the interpretation of its irreversible binding to protein in vivo.
    Biochemical pharmacology, 1979, Aug-15, Volume: 28, Issue:16

    Topics: Animals; Blood Proteins; Chemical Phenomena; Chemistry; Chloramphenicol; Glycine; Hydrolysis; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Serine; Tissue Distribution

1979
The biosynthesis of cytochrome P450 by heavy and light rough endoplasmic reticulum of rat liver.
    Biochemical and biophysical research communications, 1979, Nov-14, Volume: 91, Issue:1

    Topics: Animals; Chloramphenicol; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Kinetics; Liver; Male; Phenobarbital; Rats

1979
[Dependence of the crystal growth of solids on the intensity of size reduction on the example of various pharmaceutical agents. 2].
    Die Pharmazie, 1977, Volume: 32, Issue:10

    Topics: Chloramphenicol; Crystallization; Pharmaceutical Preparations; Phenobarbital; Pilocarpine; Prednisolone; Temperature

1977
Interaction of chloramphenicol with phenytoin and phenobarbital. Case report.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:5

    Topics: Adult; Chloramphenicol; Drug Interactions; Humans; Kinetics; Male; Phenobarbital; Phenytoin

1978
Relationship between microsomal hydroxylase and glucuronyltransferase.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Aminopyrine; Animals; Bilirubin; Biotransformation; Chloramphenicol; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Female; Glucuronosyltransferase; Hexosyltransferases; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Naphthols; Nitrophenols; Phenobarbital; Polyethylene Glycols; Rats; Sex Factors; Sonication

1975
Studies on the concentrations of chloramphenicol in the serum and cerebrospinal fluid of neonates, infants, and small children. Reciprocal reactions between chloramphenicol, penicillin and phenobarbitone.
    European journal of pediatrics, 1977, Jan-26, Volume: 124, Issue:2

    Topics: Age Factors; Child, Preschool; Chloramphenicol; Drug Interactions; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature, Diseases; Meningitis; Penicillins; Phenobarbital

1977
Inhibition of hepatic microsomal enzymes by chloramphenicol.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:2

    Topics: Animals; Benzphetamine; Chloramphenicol; Cytochrome P-450 Enzyme System; Drug Interactions; Ethylmorphine-N-Demethylase; Hexobarbital; In Vitro Techniques; Male; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Pentobarbital; Phenobarbital

1977
Combined cancer chemotherapy with cyclophoshamide and an inducer of microsomal drug-metabolizing enzymes (cytochrome P-450) in tumor-bearing rats.
    The Tohoku journal of experimental medicine, 1975, Volume: 116, Issue:4

    Topics: Animals; Chloramphenicol; Cyclophosphamide; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Male; Microsomes; Neoplasms, Experimental; Phenobarbital; Rats; Sarcoma, Yoshida

1975
Studies of the development of congenital anomalies in rats. III. Effects of inhibition of mitochondrial energy systems on embryonic development.
    Teratology, 1975, Volume: 12, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Chloramphenicol; Diet; Embryo Implantation; Energy Metabolism; Enzyme Inhibitors; Female; Fetus; Malonates; Mitochondria; Phenobarbital; Phenytoin; Pregnancy; Propylene Glycols; Rats; Teratogens

1975
[Acute tolerance and time changes in ketamine-induced sleep under the effect of phenobarbital and chlorophenicol. Experimental study].
    Revista espanola de anestesiologia y reanimacion, 1976, Volume: 23, Issue:1

    Topics: Anesthesia; Animals; Chloramphenicol; Ketamine; Male; Phenobarbital; Preanesthetic Medication; Rats; Sleep; Time Factors

1976
Purulent meningitis in children: outcome using a standard management regimen with chloramphenicol.
    Annals of tropical paediatrics, 1992, Volume: 12, Issue:4

    Topics: Bacteria; Child; Child, Preschool; Chloramphenicol; Humans; Infant; Infant, Newborn; Meningitis, Bacterial; Phenobarbital; Prospective Studies; Seizures; Treatment Outcome

1992
[Hemopoietic disorder caused by drugs--special significance placed on anemia].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Chloramphenicol; Ethanol; Humans; Methotrexate; Methyldopa; Middle Aged; Neomycin; Penicillins; Phenacetin; Phenobarbital

1991
Neonatal treatment with phenobarbital, zixoryn and chloramphenicol lack of imprinting effect of zixoryn on microsomal enzyme activities.
    Acta physiologica Hungarica, 1990, Volume: 76, Issue:4

    Topics: Animals; Animals, Newborn; Benzhydryl Compounds; Chloramphenicol; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1990
The biochemical basis for the species difference in hepatic microsomal 4-vinylcyclohexene epoxidation between female mice and rats.
    Carcinogenesis, 1990, Volume: 11, Issue:11

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chloramphenicol; Cyclohexanes; Cyclohexenes; Cytochrome P-450 Enzyme System; Female; Hydroxylation; Mice; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Rats; Species Specificity; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Testosterone

1990
Effects of chloramphenicol, cimetidine and phenobarbital on and tolerance to xylazine-ketamine anesthesia in dogs.
    Veterinary and human toxicology, 1990, Volume: 32, Issue:3

    Topics: Anesthesia; Animals; Behavior, Animal; Chloramphenicol; Cimetidine; Consciousness; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Drug Tolerance; Ketamine; Male; Phenobarbital; Reflex; Thiazines; Xylazine

1990
Characterization of a phenobarbital-inducible dog liver cytochrome P450 structurally related to rat and human enzymes of the P450IIIA (steroid-inducible) gene subfamily.
    Archives of biochemistry and biophysics, 1989, Volume: 271, Issue:2

    Topics: Amino Acid Sequence; Animals; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Enzyme Induction; Immunoblotting; Immunoglobulin G; Kinetics; Male; Microsomes, Liver; Molecular Sequence Data; Molecular Weight; NADP; Phenobarbital; Rats; Spectrophotometry; Steroid Hydroxylases; Troleandomycin

1989
[First pass effect of gallanilide in rats].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1988, Volume: 9, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Carbon Tetrachloride Poisoning; Chloramphenicol; Drug Incompatibility; Female; Gallic Acid; Lidocaine; Male; Phenobarbital; Rats; Ventricular Fibrillation

1988
On the mechanism of the inactivation of the major phenobarbital-inducible isozyme of rat liver cytochrome P-450 by chloramphenicol.
    The Journal of biological chemistry, 1985, Jul-15, Volume: 260, Issue:14

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzphetamine; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Kinetics; Male; NADPH-Ferrihemoprotein Reductase; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry; Time Factors

1985
[Use of levomycetin in acute 1,2-dichloroethane poisonings].
    Gigiena truda i professional'nye zabolevaniia, 1985, Issue:3

    Topics: Acute Disease; Animals; Chloramphenicol; Drug Evaluation; Drug Evaluation, Preclinical; Ethylene Dichlorides; Humans; Hydrocarbons, Chlorinated; Male; Mice; Middle Aged; Phenobarbital; Rats; Time Factors

1985
Isozyme selectivity of the inhibition of rat liver cytochromes P-450 by chloramphenicol in vivo.
    Molecular pharmacology, 1985, Volume: 28, Issue:3

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Chloramphenicol; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Isoenzymes; Lauric Acids; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Inbred Strains; Safrole; Steroid 16-alpha-Hydroxylase; Substrate Specificity; Testosterone; Warfarin

1985
Effect of chronic administration of centrally acting compounds on chloramphenicol metabolism in schizophrenic patients.
    Pharmacology, 1974, Volume: 11, Issue:4

    Topics: Adult; Antipsychotic Agents; Chloramphenicol; Chronic Disease; Female; Glucuronates; Half-Life; Humans; Injections, Intravenous; Liver Cirrhosis; Male; Middle Aged; Nitro Compounds; Phenobarbital; Phenothiazines; Schizophrenia

1974
Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase.
    Biochimica et biophysica acta, 1973, Nov-15, Volume: 327, Issue:1

    Topics: Ammonium Sulfate; Animals; Bilirubin; Chemical Precipitation; Chloramphenicol; Cycloheximide; Deoxycholic Acid; Enzyme Activation; Enzyme Induction; Glucuronosyltransferase; Hexosyltransferases; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Naphthols; Nitrophenols; Phenobarbital; Rats; Structure-Activity Relationship; Surface-Active Agents; Trypsin

1973
[Differences between the protein binding of newborns and adults and their importance for pharmacological action].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1968, Volume: 260, Issue:2

    Topics: Acetaminophen; Age Factors; Aminosalicylic Acids; Atropine; Chloramphenicol; Humans; Infant, Newborn; Isoniazid; Methicillin; Morphine; Nitrofurantoin; Oxyphenbutazone; Phenacetin; Phenobarbital; Phenytoin; Promethazine; Protein Binding; Salicylates; Sulfadimethoxine; Thiopental

1968
[Differential induction of microsomal N- and p-hydroxylation of aniline and N-ethylamiline in rabbits].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 257, Issue:2

    Topics: Anesthetics, Local; Aniline Compounds; Animals; Chloramphenicol; Dactinomycin; Enzyme Induction; Ethionine; Female; Hydroxylamines; Liver; Male; Microsomes; Mixed Function Oxygenases; NADP; Phenobarbital; Phenols; Rabbits

1967
Increased antitumor activity of cyclophosphamide (Endoxan) following pretreatment with inducer of drug-metabolizing enzymes (cytochrome P-450).
    The Tohoku journal of experimental medicine, 1974, Volume: 114, Issue:1

    Topics: Alkylation; Animals; Chloramphenicol; Cyclophosphamide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes; Drug Interactions; Enzyme Induction; Male; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry

1974
[Glucuroconjugation in vitro of chloramphenicol in normal rats and in rats pre-treated with phenobarbital].
    Bollettino chimico farmaceutico, 1974, Volume: 113, Issue:10

    Topics: Animals; Biopharmaceutics; Biotransformation; Chloramphenicol; Glucuronates; Male; Phenobarbital; Rats

1974
Induction of chloramphenicol metabolism by phenobarbital.
    Antimicrobial agents and chemotherapy, 1972, Volume: 1, Issue:2

    Topics: Animals; Chloramphenicol; Dogs; Enzyme Induction; Half-Life; In Vitro Techniques; Microsomes, Liver; Perfusion; Phenobarbital; Rats

1972
[Studies concerning the relationship between the release of enzymes and electrolyte shift in the liver (author's transl)].
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1974, Volume: 162, Issue:1

    Topics: Alanine Transaminase; Animals; Calcium; Carbon Tetrachloride Poisoning; Chloramphenicol; Dinitrophenols; Extracellular Space; Female; Hydrocortisone; L-Lactate Dehydrogenase; Liver; Liver Diseases; Phenobarbital; Potassium; Rats; Sodium

1974
Increase of chloramphenicol glucuronidation in rats treated with phenobarbital.
    Biochemical pharmacology, 1974, Apr-01, Volume: 23, Issue:7

    Topics: Administration, Oral; Animals; Chloramphenicol; Glucuronates; Glucuronidase; Half-Life; Hydrolysis; Injections, Intravenous; Liver; Male; Oxidation-Reduction; Phenobarbital; Rats; Stimulation, Chemical; Time Factors

1974
Modifications of the in vitro metabolism of the hepatotoxic pyrrolizidine alkaloid, monocrotaline.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:3

    Topics: Animals; Biotransformation; Chloramphenicol; In Vitro Techniques; Male; Microsomes, Liver; Oxides; Phenobarbital; Proadifen; Pyrrolizidine Alkaloids; Rats

1974
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
    Biochimica et biophysica acta, 1970, Oct-27, Volume: 222, Issue:1

    Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles

1970
[Dangers and potential uses of enzyme stimulating medication on newborns and infants].
    Padiatrie und Padologie, 1972, Volume: 7, Issue:3

    Topics: Aminopyrine; Chloramphenicol; Drug Synergism; Enzyme Induction; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice, Neonatal; Liver; Phenobarbital; Pregnancy; Stimulation, Chemical

1972
Modifications of pyrrolizidine alkaloid intoxication resulting from altered hepatic microsomal enzymes.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Animals; Chloramphenicol; Dose-Response Relationship, Drug; Drug Interactions; Injections, Subcutaneous; Lung; Male; Microsomes, Liver; Myocardium; Pentobarbital; Phenobarbital; Poisoning; Pyrrolizidine Alkaloids; Rats; Sleep

1972
Non-equivalent preparations of the same drug.
    Drug and therapeutics bulletin, 1971, Aug-13, Volume: 9, Issue:17

    Topics: Chloramphenicol; Dosage Forms; Humans; Nitrofurantoin; Oxytetracycline; Pharmaceutical Preparations; Phenindione; Phenobarbital; Phenylbutazone; Phenytoin; Tetracycline; Therapeutic Equivalency; Tolbutamide; Warfarin

1971
[Drug interactions during therapy. Blood levels of chloramphenicol in animals pretreated with luminal as an enzyme inductor].
    La Clinica terapeutica, 1971, Oct-31, Volume: 59, Issue:2

    Topics: Animals; Chloramphenicol; Drug Interactions; Enzyme Induction; Phenobarbital; Rabbits

1971
Effect of chronic treatment with therapeutically useful antibiotics on the response of certain pharmacologic agents in the rat.
    The Journal of the American Osteopathic Association, 1970, Volume: 69, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Chloramphenicol; Chlordan; Chlortetracycline; Dactinomycin; Drug Antagonism; Drug Tolerance; Enzyme Induction; Enzymes; Hexobarbital; Male; Oxytetracycline; Penicillins; Phenobarbital; Rats; Sleep; Streptomycin

1970
[Special pharmacological problems of the neonatal period from the clinical point of view].
    Zeitschrift fur arztliche Fortbildung, 1969, Jul-15, Volume: 63, Issue:14

    Topics: Ampicillin; Animals; Chloramphenicol; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Extracellular Space; Female; Humans; Infant, Newborn; Kidney; Liver; Maternal-Fetal Exchange; Oxytetracycline; Pharmaceutical Preparations; Phenobarbital; Pregnancy; Streptomycin; Sulfonamides

1969
Effects of various chemical agents on drug metabolism and cholesterol biosynthesis.
    Biochemical pharmacology, 1968, Volume: 17, Issue:7

    Topics: Acetanilides; Acetates; Aminopyrine; Animals; Anticholesteremic Agents; Benzopyrenes; Carbon Isotopes; Chloramphenicol; Cholesterol; Depression, Chemical; Drug Synergism; Ethers; Ethylamines; Hexobarbital; Insecticides; Iproniazid; Liver; Male; Mevalonic Acid; Microsomes; Nitrophenols; Phenobarbital; Proadifen; Rabbits; Rats; Sleep; Time Factors

1968
Chloramphenicol metabolism in the phenobarbital-induced rat. Comparison with thiamphenicol.
    Biochemical pharmacology, 1968, Volume: 17, Issue:12

    Topics: Acetates; Animals; Chloramphenicol; Glucuronates; Male; Phenobarbital; Pneumococcal Infections; Rats; Statistics as Topic

1968
[Effects of drug interaction in infancy (author's transl)].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1980, Volume: 128, Issue:10

    Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid

1980
Microscale ultrafiltration technique for determining free drug in 50-microL serum samples.
    Clinical chemistry, 1984, Volume: 30, Issue:6

    Topics: Animals; Chloramphenicol; Diazepam; Furosemide; Humans; Indomethacin; Infant; Infant, Newborn; Microchemistry; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Ultrafiltration; Valproic Acid

1984
Suicide inactivation of rat liver cytochrome P-450 by chloramphenicol in vivo and in vitro.
    Molecular pharmacology, 1983, Volume: 23, Issue:2

    Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzene Derivatives; Chloramphenicol; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Iodobenzoates; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1983
The pharmacokinetics of chloramphenicol in the neonate and young infant.
    The Journal of antimicrobial chemotherapy, 1983, Volume: 12, Issue:6

    Topics: Administration, Oral; Aging; Chloramphenicol; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Penicillins; Phenobarbital

1983
Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues.
    Ciba Foundation symposium, 1980, Volume: 76

    Topics: Animals; Biotransformation; Bromobenzenes; Chloramphenicol; Furans; Humans; Liver; Lung; Methylcholanthrene; Microsomes; Models, Biological; Monocrotaline; Pharmaceutical Preparations; Phenobarbital; Pyrrolizidine Alkaloids; Terpenes

1980
Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.
    Therapeutic drug monitoring, 1983, Volume: 5, Issue:1

    Topics: Adult; Anticonvulsants; Carbamazepine; Chloramphenicol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Primidone

1983
[Effects of chloramphenicol on microsomal reductases associated with lipoperoxidation (author's transl)].
    Toxicological European research. Recherche europeenne en toxicologie, 1982, Volume: 4, Issue:2

    Topics: Animals; Chloramphenicol; Cytochrome P-450 Enzyme System; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Triglycerides

1982
Non-operative management of pseudotumor cerebri caused by lateral sinus thrombosis.
    The Journal of the Kansas Medical Society, 1980, Volume: 81, Issue:10

    Topics: Child; Chloramphenicol; Dexamethasone; Female; Glycerol; Humans; Papilledema; Phenobarbital; Pseudotumor Cerebri; Sinus Thrombosis, Intracranial

1980
Interactions among chloramphenicol, phenytoin, and phenobarbital in a pediatric patient.
    The Journal of pediatrics, 1981, Volume: 98, Issue:6

    Topics: Child; Chloramphenicol; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Postoperative Complications

1981
Toxicity of hymenoxon in Swiss white mice following pretreatment with microsomal enzyme inducers, inhibitors and carbon tetrachloride.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 33, Issue:2

    Topics: Animals; Aroclors; Carbon Tetrachloride; Chloramphenicol; Chlorodiphenyl (54% Chlorine); Drug Interactions; Enzyme Induction; In Vitro Techniques; Lethal Dose 50; Liver; Mice; Microsomes, Liver; Phenobarbital; Sesquiterpenes

1981
Inactivation of purified rat liver cytochrome P-450 by chloramphenicol.
    Molecular pharmacology, 1980, Volume: 17, Issue:3

    Topics: Amino Acids; Animals; Carbon Monoxide; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; NADP; Phenobarbital; Rats

1980
Effect of induction and inhibition of drug metabolism on pharmacokinetics and anticoagulant activity of the enantiomers of phenprocoumon in rats.
    Pharmacology, 1980, Volume: 21, Issue:5

    Topics: 4-Hydroxycoumarins; Animals; Anticoagulants; Chloramphenicol; Enzyme Induction; Kinetics; Liver; Male; Phenobarbital; Phenprocoumon; Prothrombin Time; Rats

1980
Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Aminopyrine; Animals; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Induction; Free Radical Scavengers; Ketoconazole; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley

1994
UDP glucuronosyltransferase gene expression is involved in the stimulation of ascorbic acid biosynthesis by xenobiotics in rats.
    The Journal of nutrition, 1993, Volume: 123, Issue:12

    Topics: Analysis of Variance; Animals; Ascorbic Acid; Base Sequence; Blotting, Northern; Body Weight; Chloramphenicol; Gene Expression Regulation, Enzymologic; Glucuronosyltransferase; Injections, Intraperitoneal; Liver; Methylcholanthrene; Molecular Sequence Data; Nitrophenols; Organ Size; Phenobarbital; Polymerase Chain Reaction; Rats; Rats, Gunn; Rats, Inbred Strains; RNA, Messenger; Time Factors; Xenobiotics

1993
Effect of phenobarbital, 3-methylcholanthrene, and chloramphenicol pretreatment on the pharmacokinetics and pharmacodynamics of azosemide in rats.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:5

    Topics: Animals; Area Under Curve; Blood Proteins; Chloramphenicol; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Diuretics; Enzyme Induction; Enzyme Inhibitors; Half-Life; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Sulfanilamides

1997
Pharmacokinetic changes of M1, M2, M3 and M4 after intravenous administration of a new anthracycline, DA-125, to rats pretreated with phenobarbital, 3-methylcholanthrene, chloramphenicol, or SKF-525A.
    Biopharmaceutics & drug disposition, 1998, Volume: 19, Issue:2

    Topics: Animals; Anthracyclines; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Antineoplastic Agents; Carcinogens; Carotid Arteries; Chloramphenicol; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Injections, Intravenous; Jugular Veins; Male; Methylcholanthrene; Phenobarbital; Proadifen; Protein Synthesis Inhibitors; Rats; Rats, Sprague-Dawley

1998
Chloramphenicol and ampicillin-induced changes in rat hepatic esterase and amidase activities.
    Bioscience reports, 2000, Volume: 20, Issue:1

    Topics: Amidohydrolases; Ampicillin; Animals; Anti-Bacterial Agents; Carboxylic Ester Hydrolases; Chloramphenicol; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Indicators and Reagents; Isoenzymes; Liver; Male; Nitrophenols; Organophosphorus Compounds; Penicillins; Phenobarbital; Protein Synthesis Inhibitors; Proteins; Rats; Rats, Wistar

2000
Double-chambered right ventricle in a dog.
    The Journal of veterinary medical science, 2000, Volume: 62, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Antihypertensive Agents; Chloramphenicol; Dog Diseases; Dogs; Echocardiography; Electrocardiography; Enalapril; Encephalitis; Fatal Outcome; Female; Heart Septal Defects, Ventricular; Heart Ventricles; Magnetic Resonance Imaging; Phenobarbital; Prednisolone; Radiography, Thoracic; Seizures; Ventricular Dysfunction, Right

2000
MEGALOBLASTIC ANEMIA ASSOCIATED WITH THE INGESTION OF PHENOBARBITAL AND PRIMIDONE. REPORT OF A CASE IN A SIX-YEAR-OLD CHILD.
    Pediatrics, 1963, Volume: 32

    Topics: Anemia, Aplastic; Anemia, Macrocytic; Anemia, Megaloblastic; Anti-Bacterial Agents; Barbiturates; Candidiasis, Vulvovaginal; Child; Chloramphenicol; Epilepsy; Esophageal Stenosis; Intellectual Disability; Nitrofurantoin; Periodontal Diseases; Phenobarbital; Primidone; Sulfonamides; Toxicology

1963
HAEMORRHAGIC COMPLICATIONS DURING THE TREATMENT OF TETANUS.
    Lancet (London, England), 1964, Feb-29, Volume: 1, Issue:7331

    Topics: Amobarbital; Child; Chloramphenicol; Chlorpromazine; Diphenhydramine; Hematuria; Hemolysis; Hydrocortisone; Hypoprothrombinemias; Mephenesin; Meprobamate; Penicillins; Phenobarbital; Promethazine; Purpura; Purpura, Thrombocytopenic; Sulfamethizole; Sulfathiazoles; Tetanus; Tetanus Toxoid; Toxicology; Tracheotomy; Trimeprazine; Tubocurarine; Vitamin K 1

1964
LISTERIA MONOCYTOGENES MENINGITIS IN THE NEWBORN.
    Journal of the Irish Medical Association, 1964, Volume: 54

    Topics: Chloramphenicol; Clinical Laboratory Techniques; Humans; Infant, Newborn; Infant, Newborn, Diseases; Ireland; Listeria; Meningitis; Meningitis, Listeria; Mice; Penicillins; Phenobarbital; Rabbits; Research; Streptomycin

1964
WHOOPING COUGH; PRESENT TRENDS IN TREATMENT.
    Nursing times, 1964, Apr-17, Volume: 60

    Topics: Child; Chloral Hydrate; Chloramphenicol; Humans; Infant; Pertussis Vaccine; Phenobarbital; Pulmonary Atelectasis; Quarantine; Toxicology; Whooping Cough

1964
THE TREATMENT OF TETANUS.
    Pediatrics, 1964, Volume: 33

    Topics: Adolescent; Child; Chloramphenicol; Humans; Infant; Infant, Newborn; Penicillins; Phenobarbital; Statistics as Topic; Tetanus; Tetanus Antitoxin; Tetanus Toxoid; Texas; Tracheotomy

1964
THE EFFECT OF DRUGS ON THE DURATION OF TOXIC SYMPTOMS CAUSED BY SUBLETHAL DOSES OF LOCAL ANESTHETICS. AN EXPERIMENTAL STUDY ON MICE.
    Acta pharmacologica et toxicologica, 1964, Volume: 21

    Topics: Anesthetics; Anesthetics, Local; Barbiturates; Bemegride; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Ethionine; Iproniazid; Isoniazid; Lidocaine; Mepivacaine; Meprobamate; Mice; Nikethamide; Pentobarbital; Pharmacology; Phenobarbital; Research; Toxicology

1964
Effect of artemether on pentobarbitone sleep and electrical activity in rats.
    Canadian journal of physiology and pharmacology, 2007, Volume: 85, Issue:6

    Topics: Amphetamine; Animals; Antimalarials; Antipsychotic Agents; Artemether; Artemisinins; Central Nervous System Stimulants; Chloramphenicol; Chlorpromazine; Cortical Synchronization; Dose-Response Relationship, Drug; Electromyography; Female; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Pentobarbital; Phenobarbital; Rats; Rats, Wistar; Reticular Formation; Sleep; Superior Colliculi; Time Factors

2007
UDP-glucuronosyltransferase activities in human liver microsomes and in some laboratory animal species.
    Biochemical pharmacology, 1981, Sep-01, Volume: 30, Issue:17

    Topics: Adolescent; Aged; Animals; Camphanes; Chloramphenicol; Eugenol; Female; Glucuronides; Glucuronosyltransferase; Humans; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Middle Aged; Nitrophenols; Phenobarbital; Rats; Rats, Sprague-Dawley; Rats, Wistar; Species Specificity; Swine; Uridine Diphosphate

1981