phenobarbital has been researched along with carbamazepine in 1015 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 489 (48.18) | 18.7374 |
| 1990's | 244 (24.04) | 18.2507 |
| 2000's | 139 (13.69) | 29.6817 |
| 2010's | 112 (11.03) | 24.3611 |
| 2020's | 31 (3.05) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, H; Edafiogho, IO; Hinko, CN; Moore, JA; Mulzac, D; Nicholson, JM; Scott, KR | 1 |
| Edafiogho, IO; Farrar, VA; Moore, JA; Nicholson, JM; Scott, KR | 1 |
| Baron, BM; Dudley, MW; Kane, JM; Miller, FP; Sorensen, SM; Staeger, MA | 1 |
| Goehring, RR; Greenwood, TD; Nwokogu, GC; Pisipati, JS; Rogers, TG; Wolfe, JF | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Chapleo, CB; Myers, PL; Smith, AC; Tulloch, IF; Turner, S; Walter, DS | 1 |
| Chapleo, CB; Myers, M; Myers, PL; Saville, JF; Smith, AC; Stillings, MR; Tulloch, IF; Walter, DS; Welbourn, AP | 1 |
| Stillings, MR; Walter, DS; Welbourn, AP | 1 |
| Biziere, K; Brochard, J; Brodin, R; Chambon, JP; Hallot, A; Merlier, J | 1 |
| Alexander, MS; Edafiogho, IO; Farrar, VA; Kolen, KR; Moore, JA; Rankin, GO; Scott, KR; Sims, LD; Stables, JP; Tonnu, AD | 1 |
| Bastide, P; Coudert, P; Couquelet, J; Gardette, D; Moreau, S; Rubat, C; Tronche, P; Vallee-Goyet, D | 1 |
| Ciechanowicz-Rutkowska, M; Edafiogho, IO; el-Assadi, A; Farrar, VA; Filippini, G; Grochowski, J; Hinko, CN; Moore, JA; Pilati, T; Serda, P | 1 |
| Cacciaguerra, S; Delarge, J; Depovere, P; Isa, M; Masereel, B; Poupaert, JH; Spampinato, S; Stables, JP; Ucar, H; Van derpoorten, K | 1 |
| Strassburg, CP; Tukey, RH | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Chai, KY; Kwak, KC; Piao, HR; Quan, ZS; Xie, ZF | 1 |
| Pavana, RK; Raghavendran, JV; Sriram, D; Stables, J; Sudhan, K; Thirumurugan, R; Yogeeswari, P | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Alkskas, IA; Azam, F; Khokra, SL; Prakash, O | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Jain, NK; Kashaw, SK; Kashaw, V; Mishra, P; Stables, JP | 1 |
| Erdmann, F; Fischer, G; Harris, R; Hopkins, S; Huang, Z; Murray, MG; Ribeill, Y; Scorneaux, B; Smitley, C; Wring, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Ahsan, W; Siddiqui, N | 1 |
| Deng, XQ; Guan, LP; Quan, YC; Quan, ZS; Sui, X | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| He, X; Hu, X; Pan, Y; Qiu, G; Wu, W; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Sen, S; Sinha, N | 1 |
| Deng, XQ; Quan, LN; Quan, ZS; Song, MX; Wei, CX | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Guo, H; He, X; Hu, X; Qiu, G; Wu, Z; Xiao, Y; Yang, J; Zhang, T; Zhong, M | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| He, X; Hu, X; Wu, W; Wu, Z; Xiao, Y; Zhang, T; Zhong, M | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Kumari, S; Mishra, CB; Tiwari, M | 1 |
| Edayadulla, N; Ramesh, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Akhtar, MJ; Bhatia, R; Grover, G; Nath, R | 1 |
| Eadie, MJ; Lander, CM; Tyrer, JH | 2 |
| Brandt, S | 1 |
| Belvedere, G; Cantoni, L; Garattini, S; Mussini, E; Pachecka, J; Salmona, M | 1 |
| Fayle, SA; Leppik, IE; McAuliffe, JJ; Pippenger, CE; Sherwin, AL | 1 |
| Richens, A | 3 |
| Kabra, PM; Marton, LJ; Stafford, BE | 1 |
| Callaghan, N; Duggan, PF; Feely, M; O'Callaghan, M | 1 |
| Driessen, OM; Goedhart, DM; Meijer, JW | 1 |
| Buchthal, A | 1 |
| Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Egli, M | 1 |
| Mohrbacher, RJ; Riendeau, CJ; Werner, M | 1 |
| Flachs, H; Gram, L; Parnas, J | 1 |
| Cameron, JD; Hedley, DW | 1 |
| Kutt, H | 3 |
| Livingston, S; Pauli, LL; Pruce, I | 3 |
| Penin, H | 1 |
| Deisenhammer, E; Sommer, R | 2 |
| Ganes, T; Johannessen, SI; Rootwelt, K | 1 |
| Karasawa, T; Masuda, Y; Shimizu, M; Shiraishi, Y; Utsui, Y; Yoshida, K | 2 |
| Borchert, HH; Pfeifer, S; Schuster, S | 1 |
| Lidgren, L; Nilsson, BE; Wallöe, A | 1 |
| Aucamp, AK | 1 |
| Myllylä, VV | 1 |
| Green, JR; Sato, M; Troupin, AS; Wada, JA; Wake, A | 1 |
| Bleck, V; Lewin, E | 1 |
| Palmer, GC | 1 |
| Jones, DJ; Medina, MA; Palmer, GC; Stavinoha, WB | 1 |
| Albani, M; Gauchel, FD; Toseland, PA | 1 |
| Plaa, GL | 1 |
| Horton, RW; Meldrum, BS; Toseland, PA | 1 |
| Müller-Oerlinghausen, B | 1 |
| Stores, G | 1 |
| Sauer, W; Windorfer, A | 1 |
| Hammond, KB | 1 |
| Stünkel, S; Weinmann, HM; Windorfer, A | 1 |
| Trompetter-van Woerden, ML; van der Zwan, A | 1 |
| Aucamp, AK; Joubert, PH; Potgieter, GM; Verster, F | 1 |
| Fowler, GW; Julien, RM | 1 |
| Jeavons, PM | 1 |
| Klotz, U | 2 |
| Iwai, H; Kubo, S; Kuyama, C; Watanabe, S; Yokoyama, S | 1 |
| Hori, M; Ito, T; Shimizu, M; Yoshida, K | 3 |
| Conomy, JP | 1 |
| Helmsing, PJ; van der Woude, J; van Eupen, OM | 1 |
| Göbel, W; Löscher, W | 1 |
| Christensen, NJ | 1 |
| Levy, RH; Patel, IH | 1 |
| Bruni, J | 2 |
| Campbell, DJ; Godolphin, W; Urquhart, N | 1 |
| Newmark, ME; Penry, JK | 1 |
| Andersen, B; Flachs, H; Gram, L; Parnas, J; Würtz-Jørgensen, A | 1 |
| Reith, H; Schäfer, H | 1 |
| Curless, RG | 1 |
| Trimble, M | 1 |
| Berchou, RC; Lodi, RA; Sherman, JA | 1 |
| Fretthold, DW; Kumar, S; Pesh-Imam, M; Sunshine, I; Terrentine, S; Willis, CE | 1 |
| Harvey, CD; Sherwin, AL; Van Der Kleijn, E | 1 |
| Wada, JA | 1 |
| Hosokawa, K; Kugoh, T | 2 |
| Livingston, S | 1 |
| Swanson, PD | 1 |
| Stünkel, S; Windorfer, A | 1 |
| Freeman, DJ; Rawal, N | 1 |
| Shapiro, IuL; Vaĭntrub, MIa | 1 |
| Dymling, JF; Lidgren, L; Wallöe, A | 1 |
| Burk, PG; Nathanson, G; Pollack, MA | 1 |
| Bäckström, T; Jorpes, P | 1 |
| Fröscher, W | 1 |
| Rylance, GW | 1 |
| Franzini, A; Marossero, F; Ravagnati, L; Sironi, VA | 1 |
| Mastropaolo, C; Monaco, F; Mutani, R; Tondi, M | 2 |
| Kurata, K | 1 |
| Leuschner, U; Quednow, B; Walther, H | 1 |
| Barragry, JM; Makin, HL; Scott, DF; Trafford, DJ | 1 |
| Abraham, CV; Gresham, D | 1 |
| Kinawi, A; Teller, C | 1 |
| Varma, R | 2 |
| Christiansen, J; Dam, M; Hansen, BS; Kristensen, CB | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H; Seidel, D | 1 |
| Kaneko, S | 2 |
| de Zeeuw, RA; Oei, TT; van der Kleijn, E; Westenberg, HG | 1 |
| Plenge, KL | 1 |
| Kinawi, A; Min, K | 1 |
| Köhler, E; Leuschner, U; Meyer, FP; Quednow, B; Walther, H | 1 |
| Bates, D; Evered, DC; Heath, A; Howe, JG; Ratcliffe, WA; Schardt, CW; Yeo, PP | 1 |
| Rosenmund, H; Wad, N | 1 |
| Burke, DG; Halpern, B; Korth, J; Summons, R; Truscott, RJ | 1 |
| Crunelli, V; Quattrone, A; Samanin, R | 1 |
| Hewitt, TE; Kessler, G; Sievers, DL | 1 |
| Guelen, P; Knop, H; Schobten, F; van der Kleijn, E; Vree, T; Westenberg, H | 1 |
| Johannessen, SI; Vesterhus, P | 1 |
| Christiansen, J; Friis, ML; Hvidberg, EF | 1 |
| Blake, DA; Freeman, JM; Luff, RD; Niebyl, JR | 1 |
| Perucca, E; Richens, A | 1 |
| Müller-Oerlinghausen, B; Riedel, E | 1 |
| Brachet, A; Henry, P; Loiseau, P | 1 |
| Gastaut, H; Osuntokun, BO | 1 |
| Dam, M; Hvidberg, EF | 1 |
| Freeman, JM; Singer, HS | 1 |
| Carruthers, R; Kutt, H; Louis, S; Peterson, H; Solomon, G; Wasterlain, C | 1 |
| Christiansen, J; Dam, M; Jensen, A | 1 |
| Corcoran, ME; Osawa, T; Sato, M; Troupin, AS; Wada, JA; Wake, A | 1 |
| Karbowski, K; Meienberg, O | 1 |
| Consroe, P; Eisenstein, D; Martin, P | 1 |
| Eickhoff, K; Heipertz, R; Pilz, H | 1 |
| McElhatton, PR; Sullivan, FM | 1 |
| Johannessen, SI; Munthe-Kaas, AW; Strandjord, RE | 1 |
| Callaghan, N; Duggan, F; Feely, M; O'Callaghan, M; Seldrup, J | 1 |
| Brachet-Liermain, A; Centraud, B; Loiseau, P | 1 |
| Lewin, E | 1 |
| Abraham, CV | 1 |
| Adams, RF; Vandemark, FL | 1 |
| Kullander, S | 1 |
| Benna, P; Covacich, A; Durelli, L; Fantini, M; Furlan, PM; Gerna, M; Gilli, M; Monaco, F; Morselli, PL; Mutani, R; Riccio, A; Troni, W | 1 |
| Kitazawa, S; Komuro, T | 1 |
| Cramers, CA; Hulsman, JA; Meijers, CA; van Kuik, LG; Vermeer, EA | 1 |
| Kitamura, M; Nishina, T; Okoshi, K | 1 |
| Hempel, E; Klinger, W | 1 |
| Abraham, CV; Joslin, HD | 2 |
| Reynolds, EH; Trimble, MR | 1 |
| Chadwick, D; Marsden, CD; Reynolds, EH | 1 |
| Rane, A; Wilson, JT | 1 |
| Brock, JT; Cereghino, JJ; Penry, JK; Smith, LD; Van Meter, JC; White, BG | 2 |
| Johnson, J | 1 |
| Friel, P; Troupin, AS | 1 |
| Anlezark, G; Balzamo, E; Horton, RW; Meldrum, BS; Trimble, M | 1 |
| Meijer, JW; Meinardi, H; Van Der Kleijn, E; Van Rees, H | 1 |
| Dam, M; Kiørboe, E | 1 |
| Forbes, IJ; Sorrell, TC | 1 |
| Rodin, EA | 1 |
| Hill, JG; Soldin, SJ | 1 |
| Farmer, PJ; Jumbo, L; Placencia, M; Sander, JW; Shorvon, SD | 1 |
| Watanabe, M; Yagi, K | 1 |
| Baldini, S; Bottacchi, E; Carenini, L; D'Alessandro, G; Leone, M | 1 |
| Kostadinova, I; Krustev, A; Millusheva, M; Toreva, D | 1 |
| Kostadinova, I; Millusheva, M; Toreva, D | 1 |
| Kaciński, M | 1 |
| Ferron, FR; Hanzel, TE; Harder, SR; Kalachnik, JE; Mayhew, LA | 1 |
| Jacobi, G | 1 |
| Altman, HJ; Commissaris, RL; Kopchia, KL | 1 |
| Theodore, WH | 2 |
| Churchyard, A; Grainger, K; Khangure, M | 1 |
| Breckenridge, AM; Kitteringham, NR; Park, BK; Pirmohamed, M | 2 |
| Joshi, MV; Karande, SC; Kshirsagar, NA; Shah, PU | 1 |
| Baruzzi, A; Di Sarro, R; Gallassi, R; Lugaresi, E; Marra, M; Morreale, A | 1 |
| Cascante, SM; Crespo, F; Ellison, RH; Placencia, M; Sander, JW; Shorvon, SD; Suarez, J | 1 |
| Bigler, S; Hänseler, E; Wad, N | 1 |
| Cavalheiro, EA; Dziki, M; Kleinrok, Z; Parada, J; Turski, W | 1 |
| Bonneton, J; Dravet, C; Genton, P; Mesdjian, E; Roger, J; Sennoune, S | 1 |
| Cheymol, G; Lebot, M; Poirier, JM | 1 |
| Doré, C; Hudson, S; Wann, K; Wardley-Smith, B | 1 |
| Hudda, MM; Kim, CK; Pinel, JP; Wong, DJ; Yung, A | 1 |
| Beslo, D; Niketić, V; Raicević, S; Sredić, S; Stojković, M | 1 |
| Duchowny, M | 1 |
| Cornel, MC; Lindhout, D; Omtzigt, JG | 1 |
| Friel, PN; McCormick, K; Yerby, MS | 1 |
| Benedetti, TJ; Erickson, DM; Leavitt, A; Loewenson, RB; McCormick, KB; Sells, CJ; Yerby, MS | 1 |
| Lindhout, D; Meijer, JW; Meinardi, H; Nau, H | 1 |
| Breckenridge, AM; Guenthner, TM; Kitteringham, NR; Park, BK; Pirmohamed, M | 1 |
| Baba, A; Hori, T; Kawai, N; Koizumi, J; Moroji, T; Shiraishi, H; Suzuki, T; Tada, K | 1 |
| Fujita, M; Goto, S; Kida, M; Kubotsu, K; Matsuura, S; Sakurabayashi, I; Takano, S; Tuchiya, H | 1 |
| Peterson, SL | 1 |
| Feksi, AT; Gatiti, S; Kaamugisha, J; Sander, JW; Shorvon, SD | 1 |
| Declerck, AC; Wauquier, A | 1 |
| Clarke, BM; Griffin, H; Hudoba, P; Upton, A | 1 |
| Breimer, DD; de Boer, AG; van Hoogdalem, E | 1 |
| Lluch Fernández, MD; Montoya García, MJ; Peña Griñán, MJ; Pérez Cano, R; Ramos Sánchez, I | 1 |
| Burns, EA; Gennis, MA; Hill, JV; Miller, MA; Spielberg, SP; Vemuri, R | 1 |
| Burlina, A; Mould, GP; Müller, C; Stamp, RJ | 1 |
| Bermes, EW; Garbincius, J; Jandreski, MA; Shah, JC | 1 |
| Baruchello, M; Brignolio, F; Verzè, L | 1 |
| Boiko, S; Breneman, DL; Kleier, RS | 1 |
| Fredow, G; Löscher, W | 1 |
| Foster, GR; Freeth, CJ; Goldin, RD; Nieman, E; Oliveira, DB | 1 |
| Heller, AJ; Johnson, AL; Marshall, WJ; Reynolds, EH; Ring, HA | 1 |
| Alonso, C; Camiña, MF; Gómez, M; Paz, JM; Rodriguez-Segade, S; Rozas, I | 1 |
| Alonso, C; Camiña, MF; Castro-Gago, M; Paz, JM; Rodriguez-Segade, S; Rozas, I | 1 |
| Ishikawa, S; Izumi, M; Okada, H; Takeda, A; Tanaka, H | 1 |
| Feld, S; Konichezky, S; Mor, E; Shapira, OM | 1 |
| McNamara, JO; Shin, C; Silver, JM | 1 |
| Bates, SR; Hug, G; Landrigan, EA; McGraw, CA | 1 |
| Dupuis, RE; Miranda-Massari, J | 1 |
| Giardina, M; Pacifici, R; Paris, L; Pichini, S; Sideri, G; Zuccaro, P | 1 |
| Löscher, W; Wahnschaffe, U | 1 |
| Haginaka, J; Wakai, J; Yasuda, H | 1 |
| Hadders-Algra, M; Huisjes, HJ; Touwen, BC; van der Pol, MC | 1 |
| Schramm, W; Smith, RH | 1 |
| Holmes, GL | 1 |
| Smith, DB | 1 |
| Hönack, D; Löscher, W; Wahnschaffe, U | 1 |
| Blazquez, A; Calandre, EP; Cano, D; Rodriquez-Lopez, C | 1 |
| Fazio, A; Martines, C; Pisani, F; Spina, E; Tomson, T; Trio, R | 1 |
| Greenwood, RS; Miles, MV; Tennison, MB | 1 |
| Davis, SJ; Hullin, DA; Thomas, KC | 1 |
| Lustman, LI; Maccario, M | 1 |
| Aguado-Vega, M; Arranz Peña, MI; Rubí Cervino, J; Seijas Martínez-Echevarría, MV | 1 |
| Briggle, TV; Guterman, A; McManus, DQ; Perchalski, R; Ramsay, RE; Vazquez, D; Wong, P; Yost, RA | 1 |
| Chen, SS; Shen, MR | 1 |
| Eadie, MJ; Herkes, GK | 2 |
| Matisová, E; Pham Thi, Ha; Volmut, J | 1 |
| Fogel, BS; McNamara, ME | 1 |
| Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H | 1 |
| Gerasimiuk, DL; Gusel', VA; Klimenko, VA; Korovin, AM | 1 |
| Dawson, CM; Rainbow, SJ; Tickner, TR | 1 |
| Dimanico, U; Gianelli, M; Monaco, F; Mutani, R | 1 |
| Perrett, JE; Richens, A; Tsanaclis, LM; Williams, J; Wilson, JF | 1 |
| Cosgrove, M; Pople, S; Wallace, SJ | 1 |
| Kahn, D; Schneier, HA | 1 |
| Endo, K; Hagimoto, H; Ishii, M; Miyauchi, T; Tanaka, K; Yamaguchi, T | 1 |
| Bausch, S; Blackwood, J; Gassmann, S; Grün, K; Inbar, S; Kreider, R; Löchel, B; Siebert, M; Walter, G | 1 |
| Bun, H; Cano, JP; Durand, A; Monjanel-Mouterde, S; Noel, F | 1 |
| Jürgens, U; May, T; Rambeck, B; Schnabel, R; Villagrán, R | 2 |
| Trimble, MR | 2 |
| Hirose, S; Jibiki, I; Kubota, T; Yamaguchi, N | 1 |
| Hönack, D; Löscher, W | 1 |
| Aoyama, T; Higuchi, S; Hirata, K; Ichikou, N; Ieiri, I; Yamada, H | 1 |
| Aoyama, T; Higuchi, S; Hirata, K; Ieiri, I; Yamada, H | 1 |
| Goldberg, VD; Hjelm, M; Ratnaraj, N | 2 |
| Benoit, SE; Ehle, AL; Greenwood, RS; Messenheimer, JA; Miles, MV; Tennison, MB; Thorn, MD | 1 |
| Gallagher, BB; Huh, K; King, DW; Loring, DW; Meador, KJ | 1 |
| Goldbach, M; Phillips, MJ; Roberts, EA; Spielberg, SP | 1 |
| Emori, K; Minabe, Y | 1 |
| Allan, MJ; Brent, DA; Brown, RV; Crumrine, PK; Varma, R | 1 |
| Adams, HR; Frye, GD; Peterson, SL; Trzeciakowski, JP | 1 |
| Avanzini, G; Binelli, S; Casazza, M; Franceschetti, S; Lodrini, S; Panzica, F; Pluchino, F; Solero, CL | 1 |
| Joice, PD; Karunanayake, EH; Meijer, JW; Meinardi, H; Peiris, JB | 1 |
| Friel, PN; Koerner, M; Leavitt, AM; McCormick, K; Sells, CJ; Van Allen, M; Yerby, JA; Yerby, MS | 1 |
| Macdonald, RL; McLean, MJ; Skerritt, JH | 1 |
| Burnham, WM; Mace, JA | 1 |
| Garcia de la Serrana, H; Mota, C; Puche, E; Saucedo, R | 1 |
| Blehaut, H; Garat, A; Houin, G; Lachau, S; Montastruc, JL; Rascol, A; Rascol, O; Squalli, A; Tor, J | 1 |
| Leary, PM; Luss, K | 1 |
| Baty, C; Jambou, J; Leducq, B; Richard, L | 1 |
| de la Peña, CA; Del Río, R; Fernandez, MP; Paz, JM; Rodriguez-Segade, S; Rozas, I; Tutor, JC | 1 |
| Hasegawa, T; Johno, I; Kitazawa, S; Ohshima, T | 1 |
| Moore, FM; Simpson, D | 1 |
| Morrow, JI; Routledge, PA | 1 |
| Horibe, Y; Ito, Y; Iwaki, M; Ogiso, T; Yoneda, I | 1 |
| Fukuyama, Y; Hara, H | 1 |
| Cennamo, M; Piccione, E; Ticconi, C | 1 |
| Franceschetti, S; Hamon, B; Heinemann, U; Konnerth, A; Yaari, Y | 1 |
| Eadie, MJ; Herkes, GK; McKinnon, GE | 1 |
| Privitera, MD | 1 |
| Kubová, H; Mares, P; Roztocilová, L; Velísek, L | 1 |
| Pellock, JM | 2 |
| Barbour, HM; Wenham, PR | 1 |
| Cramer, JA; Mattson, RH; McCutchen, CB | 1 |
| Knott, C; Reynolds, F | 3 |
| Brown, WA; Fruzzetti, AE; Keitner, GI; Miller, IW; Norman, WH | 1 |
| Czuczwar, SJ; Janusz, W; Kleinrok, Z; Szczepanik, B; Wamil, A | 1 |
| Chen, LS; Maltby, DA; McNamara, JO; Millington, DS | 1 |
| Morselli, PL | 1 |
| Iri, H; Kano, S; Kikuchi, H; Matsumoto, K; Takahashi, H; Umino, M | 1 |
| Dow, KE; Riopelle, RJ | 1 |
| Fortman, CS; Witte, DL | 1 |
| Ashy, AR; el-Sayed, YM; Islam, SI | 1 |
| Higashi, A; Inotsume, N; Kinoshita, E; Matsuoka, T; Nakano, M | 1 |
| Bender, AS; Hertz, L | 1 |
| Samanin, R; Tullii, M; Vezzani, A; Wu, HQ | 1 |
| Hartshorn, EA; Hartshorn, JC | 1 |
| Kodama, S; Komatsu, M; Konishi, H; Matsuo, T; Momota, K; Tanaka, K; Wada, H; Yokoyama, S | 1 |
| Inoue, M; Matsuo, T; Ogata, N | 1 |
| Kishita, C | 1 |
| Canevini, MP; Canger, R; Cornaggia, CM; Giuccioli, D; Pruneri, C | 1 |
| Gal, J; Molitoris, BA; Nakata, LM; Sedman, AJ | 1 |
| Buchanan, N | 1 |
| Clemmesen, L; Flachs, H; Hemmingsen, R; Ulrichsen, J | 1 |
| Berry, DJ; Newbery, JE; Pettit, LI; Streete, JM | 1 |
| Baker, M; Bissessar, A; Callaghan, N; Crowley, M; Goggin, T; Gough, H | 1 |
| Baciewicz, AM | 1 |
| Bova, VE | 1 |
| Lee, EK; Walters, JR; Waszczak, BL | 1 |
| Mondadori, C; Schmutz, M | 1 |
| Freed, WJ; Schwarz, SS | 1 |
| Frost, JD; Glaze, DG; Hrachovy, RA; Kellaway, P; Mizrahi, EM | 1 |
| Shinnar, S | 1 |
| Browning, RA; Faingold, CL | 1 |
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| Abe, K; Hashimura, M; Iha, HA; Iwai, C; Kato, M; Kawaji, S; Kawakita, K; Kunisawa, N; Ogawa, M; Ohno, Y; Shimizu, S | 1 |
| de Baat, C; Vissink, A; Zweers, PGMA | 1 |
| Horino, A; Imai, K; Inoue, Y; Kagawa, Y; Nishida, T; Takahashi, Y; Usui, N; Yamamoto, Y | 1 |
| Francesconi, P; Gualdani, E; Palumbo, P; Policardo, L; Zaccara, G | 1 |
| Marson, AG; Nevitt, SJ; Tudur Smith, C | 1 |
| Aebisher, D; Bartusik-Aebisher, D; Buszewicz, G; Kołodziejczyk, P; Mróz, K; Mróz, T; Tutka, P; Łuszczki, JJ | 1 |
| Kasinathan, A; Sahu, JK; Sankhyan, N; Sharawat, IK | 1 |
| Chmielewski, J; Daniluk, J; Florek-Łuszczki, M; Karwan, S; Sawicka, KM; Wawryniuk, A; Łuszczki, JJ | 1 |
| Gut-Lepiech, A; Karwan, S; Kondrat-Wróbel, MW; Marzeda, P; Plech, T; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
| Ishikawa, N; Kobayashi, M; Kobayashi, Y; Tani, H; Tateishi, Y | 1 |
| Baudou, E; Cances, C; Dimeglio, C; Hachon Lecamus, C | 1 |
| Colebunders, R; Delahaye, L; Hotterbeekx, A; Idro, R; Mandro, M; Ogwang, R; Stove, CP; Velghe, S | 1 |
| Banach, M; Borowicz-Reutt, KK; Rudkowska, M | 1 |
| Basnet, A; Dhir, V; Dhooria, A; Jain, S; Jha, S; Krishnaraju, VS; Ranjan Kumar, R | 1 |
| Bien, CG; Brandt, C; Hagemann, A; Klimpel, D; May, TW | 1 |
| Limotai, C; Limotai, N; Mokklaew, J; Pattanasilp, B; Phayaph, N | 1 |
| Barker-Haliski, M; Knox, KM; Koneval, Z; Memon, A; White, HS; Zierath, DK | 1 |
| Czuczwar, SJ; Raszewski, G; Łukawski, K | 1 |
| Araki, Y; Fukushima, Y; Imai, K; Kagawa, Y; Takahashi, Y; Terada, K; Yamamoto, Y | 1 |
| Asai, S; Imai, K; Kagawa, Y; Nishida, T; Shiratani, Y; Takahashi, Y; Usui, N; Yamamoto, Y | 1 |
| Drabik, M; Florek-Łuszczki, M; Głuszak, M; Jankiewicz, M; Kozińska, J; Plech, T; Plewa, Z; Wróblewska-Łuczka, P; Łuszczki, JJ | 1 |
| Banach, M; Borowicz-Reutt, KK | 1 |
| Demir, O; Kaplan, YC | 1 |
| Kumar, J; Meena, J; Saini, L; Yadav, J | 1 |
| Li, J; Li, N; Lin, W; Zhao, D | 1 |
| Douxfils, J; Hainaut, P; Hardy, M; Larock, AS; Lessire, S; Mullier, F; Sennesael, AL; Spinewine, A | 1 |
| Bertram, EH; Edelbroek, P | 1 |
| Adams, J; Carlson, JM; Dhillon, R; Holmes, LB; Janulewicz, PA; Macklin, EA; Phillips, C; Schomer, DL; Tosches, WA | 1 |
| Alves, G; Falcão, A; Fortuna, A; Meirinho, S; Rodrigues, M | 1 |
| Cai, M; Guo, X; Han, Y; Lin, W; Yang, J; Zhong, R | 1 |
| Allegaert, K; Yalcin, N | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
| Banach, M; Borowicz-Reutt, K | 2 |
| Biliaminu, SA; N Adeboye, MA; Ojuawo, A; Omefe, PN | 1 |
| Bernat, P; Kołodziejczyk, P; Tutka, P; Zagaja, M; Łuszczki, JJ | 1 |
| Bettinotti, M; Boldt, ABW; de Paola, L; Glehn, CQCV; Silvado, CES; Spina Tensini, T | 1 |
| Jiang, R; Mei, S; Zhang, D; Zhao, Z | 1 |
| Aricò, M; Di Noia, SP; Kalolo, A; Mabusi, MS; Mastrangelo, M; Pisani, F | 1 |
| Bojar, H; Chmielewski, J; Florek-Łuszczki, M; Jankiewicz, K; Skalicka-Woźniak, K; Łuszczki, JJ | 1 |
110 review(s) available for phenobarbital and carbamazepine
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic | 2000 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Synthetic and therapeutic perspectives of nitrogen containing heterocycles as anti-convulsants.
Topics: Animals; Anticonvulsants; Heterocyclic Compounds; Humans; Molecular Structure; Seizures; Structure-Activity Relationship | 2020 |
Interactions with antiepileptic drugs.
Topics: Acetaminophen; Acetazolamide; Anti-Anxiety Agents; Anticoagulants; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Furosemide; Gonadal Steroid Hormones; Griseofulvin; Humans; Phenobarbital; Phenytoin; Primidone; Thiazines; Urea; Valproic Acid; Vitamin D | 1977 |
[Pharmacotherapy of epilepsy. II].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Benzodiazepines; Carbamazepine; Epilepsy; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines; Valproic Acid | 1978 |
Psychotropic effect of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Mental Processes; Personality Inventory; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychotropic Drugs; Thiazines; Valproic Acid | 1979 |
[Long-term anticonvulsant therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chronic Disease; Clonazepam; Epilepsy; Ethosuximide; Humans; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
The pharmacological treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Myoclonic; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Primidone; Spasms, Infantile; Status Epilepticus; Thyroid Gland | 1979 |
The medical treatment of epilepsy: initiation of drug therapy.
Topics: Adolescent; Adrenocorticotropic Hormone; Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Acute toxicity of antiepileptic drugs.
Topics: Acute Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dogs; Humans; Phenobarbital; Phenytoin; Poisoning; Primidone; Thiazines | 1975 |
Behavioural effects of anti-epileptic drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Confusion; Disorders of Excessive Somnolence; Epilepsy; Ethosuximide; Humans; Hyperkinesis; Learning Disabilities; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced; Psychotropic Drugs; Thiazines | 1975 |
Drugs and children: methods for therapeutic monitoring.
Topics: Carbamazepine; Child; Child, Preschool; Chloramphenicol; Chromatography, Gas; Colorimetry; Drug Therapy; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Humans; Immunoassay; Infant; Infant, Newborn; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Quality Control; Spectrophotometry; Sulfonamides; Theophylline | 1977 |
[Laboratory controls in long-term treatment with anticonvulsive drugs (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestinal Absorption; Male; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1977 |
[Antiepileptics during pregnancy and lactation. Pharmacokinetic data].
Topics: Anticonvulsants; Bromides; Carbamazepine; Clonazepam; Diazepam; Ethosuximide; Female; Fetus; Humans; Kinetics; Lactation; Maternal-Fetal Exchange; Nitrazepam; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1979 |
The medical treatment of epilepsy: maintenance of drug therapy.
Topics: Adolescent; Adult; Anticonvulsants; Biological Availability; Bromides; Carbamazepine; Child; Dextroamphetamine; Drug Administration Schedule; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Menstruation; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1979 |
The effect of anti-convulsant drugs on cognitive abilities.
Topics: Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Psychological Tests | 1979 |
Pharmacological prophylaxis in the kindling model of epilepsy.
Topics: Amygdala; Anesthetics, Local; Animals; Antidepressive Agents, Tricyclic; Atropine; Aziridines; Carbamazepine; Catecholamines; Cats; Cerebral Cortex; Chlorpromazine; Clorazepate Dipotassium; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Epilepsy; Haplorhini; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Reserpine; Seizures; Valproic Acid | 1977 |
Clinical pharmacokinetics of anticonvulsants.
Topics: Administration, Oral; Adult; Aged; Aging; Animals; Anticonvulsants; Carbamazepine; Child; Clonazepam; Diazepam; Drug Interactions; Ethosuximide; Female; Humans; Hydantoins; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Intestinal Absorption; Kidney Diseases; Kinetics; Liver Diseases; Milk; Molecular Biology; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1976 |
[Neurotoxicity of antiepileptic drugs].
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Ethosuximide; Humans; Male; Nervous System; Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1992 |
[The effect of monotherapy on concentration of selected blood serum hormones and upon cognitive function of children with epilepsy].
Topics: Adolescent; Carbamazepine; Child; Cognition; Epilepsy; Female; Follow-Up Studies; Humans; Male; Phenobarbital; Primidone; Psychomotor Performance; Regression Analysis; Thyroid Hormones | 1992 |
[Post-traumatic epilepsy].
Topics: Brain Injuries; Carbamazepine; Child; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Post-Traumatic; Humans; Neurologic Examination; Phenobarbital; Risk Factors; Skull Fractures | 1992 |
Rational use of antiepileptic drug levels.
Topics: Carbamazepine; Half-Life; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1992 |
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid | 1991 |
[Phosphorus-calcium metabolism in children under prolonged treatment with anticonvulsants. (II)].
Topics: Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Phosphorus; Valproic Acid | 1991 |
Anticonvulsants: pharmacotherapeutic issues in the critically ill patient.
Topics: Anticonvulsants; Benzodiazepines; Brain Injuries; Carbamazepine; Central Nervous System Diseases; Epilepsy; Humans; Pentobarbital; Phenobarbital; Phenytoin; Postoperative Complications; Seizures; Substance Withdrawal Syndrome | 1991 |
Cognitive effects of antiepileptic drugs.
Topics: Anticonvulsants; Brain Diseases; Carbamazepine; Cognition; Drug Tolerance; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Antiepileptic drugs, cognitive function, and behavior in children: evidence from recent studies.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Child; Cognition; Cognition Disorders; Epilepsy; Humans; Phenobarbital; Phenytoin; Psychological Tests; Research Design; Valproic Acid | 1990 |
Poisoning by anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
[Problems of neurological drug therapy in pregnancy].
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Antiparkinson Agents; Carbamazepine; Chelating Agents; Female; Fetus; Haloperidol; Humans; Nervous System Diseases; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Trimethadione; Valproic Acid | 1989 |
Efficacy and adverse effects of antiepileptic drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy | 1989 |
Therapeutic drug monitoring in childhood.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbamazepine; Child; Chloramphenicol; Digoxin; Drug Interactions; Half-Life; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Saliva; Theophylline; Valproic Acid | 1986 |
Carbamazepine drug interactions.
Topics: Carbamazepine; Cimetidine; Dextropropoxyphene; Drug Interactions; Erythromycin; Humans; Isoniazid; Lithium; Phenobarbital; Phenytoin; Primidone; Protein Binding; Troleandomycin; Valproic Acid; Warfarin | 1986 |
Antiepileptic drugs in adolescents.
Topics: Adaptation, Psychological; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Sports; Valproic Acid | 1987 |
Mechanisms of anticonvulsant drug action. I. Drugs primarily used for generalized tonic-clonic and partial epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Humans; Kinetics; Phenobarbital; Phenytoin | 1987 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
Anticonvulsant drugs and cognitive function: a review of the literature.
Topics: Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Epilepsy; Humans; Phenobarbital; Phenytoin | 1987 |
[Neurotraumatology and post-traumatic epilepsy. Prevention, treatment and long-term follow-up. Barbexaclone + phenobarbital (maliasin) versus diphenylhydantoin, phenobarbital, primidone, carbamazepine].
Topics: Adolescent; Adult; Anticonvulsants; Brain Injuries; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Pharmacokinetics of anti-epileptic drugs in the dog: a review.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Clonazepam; Diazepam; Dog Diseases; Dogs; Epilepsy; Ethosuximide; Kinetics; Phenobarbital; Phenytoin; Primidone; Species Specificity; Trimethadione; Valproic Acid | 1985 |
Usefulness of blood levels of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chloramphenicol; Chlordiazepoxide; Chlorpromazine; Chromatography, Gas; Dextropropoxyphene; Diazepam; Dicumarol; Disulfiram; Drug Interactions; Epilepsy; Ethosuximide; Humans; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenylbutazone; Phenytoin; Primidone; Prochlorperazine; Sulfamethizole; Sulfaphenazole; Thiazines | 1974 |
Toxic effects of anticonvulsants: general principles.
Topics: Adrenocorticotropic Hormone; Adult; Anticonvulsants; Benzodiazepinones; Body Surface Area; Body Weight; Carbamazepine; Child; Chlorobenzenes; Diagnosis, Differential; Diazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Half-Life; Humans; Nitro Compounds; Phenobarbital; Phenytoin; Primidone; Succinimides; Tranquilizing Agents; Trimethadione | 1974 |
The management of children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Ethosuximide; Humans; Infant; Infant, Newborn; Phenobarbital; Phenytoin; Primidone; Thiazines | 1970 |
Epilepsy.
Topics: Animals; Brain; Carbamazepine; Diet Therapy; Epilepsy; Humans; Phenobarbital; Phenytoin | 1972 |
Epilepsy in the adolescent.
Topics: Acetazolamide; Adolescent; Age Factors; Alcoholic Intoxication; Amphetamine; Anticonvulsants; Attitude to Health; Carbamazepine; Cerebral Cortex; Contraceptives, Oral; Drug Interactions; Electroencephalography; Epilepsy; Female; Humans; Lysergic Acid Diethylamide; Male; Phenobarbital; Phenytoin; Psychology; Puberty; Substance-Related Disorders | 1974 |
The use of blood levels of antiepileptic drugs in clinical practice.
Topics: Administration, Oral; Adult; Anticonvulsants; Biopharmaceutics; Carbamazepine; Child; Drug Tolerance; Epilepsy; Ethosuximide; Humans; Injections, Intramuscular; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Sleep; Time Factors | 1974 |
[Advance and clinic of antiepileptic drugs (author's transl)].
Topics: Animals; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Epilepsy; Humans; Ion Channels; Mice; Neurotransmitter Agents; Phenobarbital; Phenytoin; Rats; Receptors, Cell Surface; Receptors, GABA-A; Valproic Acid | 1981 |
The effects of drugs on the distribution and metabolism of thyroid hormones.
Topics: Animals; Antithyroid Agents; Carbamazepine; Carcinogens; Female; Heparin; Hormones; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Propranolol; Salicylates; Thyroid Hormones; Thyroxine-Binding Proteins | 1981 |
Reassessment of the concept of a therapeutic range of anticonvulsant plasma levels.
Topics: Anticonvulsants; Binding Sites; Brain Chemistry; Carbamazepine; Drug Therapy, Combination; Genetic Variation; Half-Life; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Time Factors | 1983 |
Diagnosis and treatment of epilepsy.
Topics: Automatism; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Epilepsy, Temporal Lobe; Ethosuximide; Humans; Muscle Tonus; Phenobarbital; Phenytoin; Primidone; Telemetry; Valproic Acid | 1983 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Kidney; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Tissue Distribution; Trimethadione; Valproic Acid | 1984 |
Interactions between anticonvulsants and other commonly prescribed drugs.
Topics: Analgesics; Anti-Infective Agents; Anticoagulants; Anticonvulsants; Benzodiazepines; Biotransformation; Carbamazepine; Drug Interactions; Humans; Intestinal Absorption; Kinetics; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Succinimides; Sulfonamides; Tissue Distribution; Valproic Acid | 1984 |
Clinical pharmacokinetics of antiepileptic drugs in adults.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Disease; Ethosuximide; Female; Humans; Kinetics; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva; Valproic Acid | 1980 |
Pharmacological principles in the long-term treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Kinetics; Long-Term Care; Phenobarbital; Phenytoin; Primidone; Succinimides; Valproic Acid | 1981 |
[The post-traumatic epilepsy (author's transl)].
Topics: Brain Concussion; Brain Injuries; Brain Neoplasms; Carbamazepine; Diagnostic Errors; Electroencephalography; Ependymoma; Epilepsy, Post-Traumatic; Humans; Phenobarbital; Phenytoin; Primidone; Skull | 1981 |
The epileptic mother and her child.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal Exchange; Milk, Human; Phenobarbital; Phenytoin; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Protein Binding; Status Epilepticus; Valproic Acid | 1982 |
Antiepileptic therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
Use of antiepileptic drugs in the presence of liver and kidney diseases: a review.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Half-Life; Humans; Kidney Diseases; Kinetics; Liver Diseases; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Drug interactions with valproic acid.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Fatty Acids, Nonesterified; Humans; Kinetics; Phenobarbital; Phenytoin; Primidone; Salicylates; Valproic Acid | 1982 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digoxin; Female; Fetus; Furosemide; Gentamicins; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Lidocaine; Penicillins; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Tetracycline; Theophylline | 1981 |
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents | 1995 |
Newer antiepileptic drugs. Towards an improved risk-benefit ratio.
Topics: Acetamides; Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Piracetam; Propylene Glycols; Risk Factors; Tiagabine; Topiramate; Triazines; Vigabatrin; Zonisamide | 1994 |
Standard approach to antiepileptic drug treatment in the United States.
Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Drug Administration Schedule; Drug Therapy, Combination; Drug Utilization; Epilepsy; Ethosuximide; Humans; Medicine; Phenobarbital; Specialization; United States; Valproic Acid | 1994 |
Standard approach to antiepileptic drug treatment in the United Kingdom.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Prognosis; United Kingdom; Valproic Acid | 1994 |
Pharmacologic intervention and treatment of childhood seizure disorders: relative efficacy and safety of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Child; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Humans; Mice; Phenobarbital; Phenytoin; Treatment Outcome; Valproic Acid | 1994 |
Treatment of status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Status Epilepticus | 1993 |
Adverse effects of established and new antiepileptic drugs: an attempted comparison.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; gamma-Aminobutyric Acid; Gastrointestinal Diseases; Humans; Nervous System Diseases; Oxcarbazepine; Phenobarbital; Phenytoin; Sleep Stages; Vigabatrin | 1995 |
Optimisation of antiepileptic drug therapy. The importance of serum drug concentration monitoring.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin | 1996 |
Clinically significant pharmacokinetic drug interactions with carbamazepine. An update.
Topics: Analgesics, Non-Narcotic; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Carbamazepine; Drug Interactions; Ethosuximide; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Valproic Acid | 1996 |
[Neonatal seizures: the beginning and interruption of the treatment].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Humans; Phenobarbital; Seizures; Treatment Outcome | 1997 |
Anticonvulsant hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Drug Interactions; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Syndrome | 1997 |
Antiepileptic drug review: part 1.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1998 |
Standards of laboratory practice: antiepileptic drug monitoring. National Academy of Clinical Biochemistry.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Drug Interactions; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Valproic Acid | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Antiepileptic drug hypersensitivity syndrome.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Diagnosis, Differential; Drug Hypersensitivity; Epilepsy; Exanthema; Humans; Incidence; Male; Phenobarbital; Phenytoin; Primidone; Syndrome | 1998 |
Population pharmacokinetics of lamotrigine adjunctive therapy in adults with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Phenytoin; Primidone; Randomized Controlled Trials as Topic; Retrospective Studies; Triazines | 1999 |
Monostars: an aid to choosing an antiepileptic drug as monotherapy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Administration Schedule; Epilepsy; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Practice Patterns, Physicians'; Triazines; Valproic Acid; Vigabatrin | 1999 |
Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.
Topics: Acute Disease; Animals; Carbamazepine; Cathartics; Charcoal; Dapsone; Drug Therapy, Combination; Humans; Phenobarbital; Poisoning; Quinine; Theophylline | 1999 |
Therapeutic safety monitoring: what to look for and when to look for it.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Monitoring; Epilepsy; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2000 |
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials.
Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; Diazepam; Epilepsy; Humans; Lorazepam; Models, Statistical; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk; Seizures; Treatment Outcome; Valproic Acid | 2001 |
Carbamazepine versus phenobarbitone monotherapy for epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Humans; Phenobarbital; Randomized Controlled Trials as Topic | 2003 |
Cancer risk in people with epilepsy: the role of antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neoplasms; Phenobarbital; Phenytoin; Rats; Risk Factors; Valproic Acid | 2005 |
Mechanisms regulating toxicant disposition to the embryo during early pregnancy: an interspecies comparison.
Topics: Animals; Biological Transport; Carbamazepine; Embryonic Development; Female; Humans; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Placenta; Pregnancy; Rabbits; Rats; Salicylic Acid; Species Specificity; Teratogens; Toxicity Tests; Tretinoin; Valproic Acid; Yolk Sac | 2004 |
Therapeutic monitoring of antiepileptic drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2007 |
Pharmacokinetics of antiepileptic drugs in elderly nursing home residents.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Nursing Homes; Phenobarbital; Phenytoin; Valproic Acid | 2007 |
[Neuromuscular disorders caused by adverse effects of antiepileptics].
Topics: Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Neuromuscular Diseases; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Zonisamide | 2007 |
[Effects of antiepileptic drugs on mood of people with epilepsy].
Topics: Affect; Anticonvulsants; Antidepressive Agents; Carbamazepine; Depressive Disorder; Epilepsy; Fructose; Humans; Lamotrigine; Mood Disorders; Oxcarbazepine; Patient Compliance; Phenobarbital; Psychometrics; Topiramate; Triazines; Vigabatrin | 2007 |
The treatment of the first seizure: the benefits.
Topics: Actuarial Analysis; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenobarbital; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Secondary Prevention; Treatment Outcome; Valproic Acid | 2008 |
Antiepileptic drugs as human teratogens.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2008 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
Side effects of phenobarbital in epilepsy: a systematic review.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Cohort Studies; Cross-Over Studies; Data Collection; Data Interpretation, Statistical; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Randomized Controlled Trials as Topic; Research; Research Design; Treatment Outcome; Valproic Acid | 2011 |
The effects of antiepileptic drugs on oral health.
Topics: Alveolar Bone Loss; Anticonvulsants; Carbamazepine; Epilepsy; Gingival Hyperplasia; Humans; Oral Health; Phenobarbital; Phenytoin | 2011 |
Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Induction Chemotherapy; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Recurrence; Seizures; Time Factors; Valproic Acid | 2013 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2013 |
Seizures and intracranial hemorrhage.
Topics: Anticonvulsants; Carbamazepine; Congenital Abnormalities; Eclampsia; Epilepsy; Female; Folic Acid; Heparin; Humans; Infant, Newborn; Intracranial Hemorrhages; Lamotrigine; Monitoring, Physiologic; North America; Phenobarbital; Phenytoin; Pregnancy; Risk Factors; Seizures; Subarachnoid Hemorrhage; Triazines; Valproic Acid; Vitamin K | 2013 |
Developmental neurotoxicity and anticonvulsant drugs: a possible link.
Topics: Animals; Anticonvulsants; Breast Feeding; Carbamazepine; Cognition Disorders; Developmental Disabilities; Female; Humans; Lamotrigine; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Triazines; Valproic Acid | 2014 |
Antiepileptic drugs as prophylaxis for post-craniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2015 |
Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Randomized Controlled Trials as Topic | 2015 |
[Preconceptional and perinatal challenges of pregnancy in women with epilepsy].
Topics: Adult; Amines; Anticonvulsants; Benzodiazepines; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsy; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Oxcarbazepine; Parturition; Perinatal Care; Phenobarbital; Phenytoin; Piracetam; Preconception Care; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Teratogens; Triazines; Valproic Acid | 2016 |
Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Randomized Controlled Trials as Topic; Remission Induction; Seizures | 2016 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drug monotherapy for epilepsy: a network meta-analysis of individual participant data.
Topics: Adult; Amines; Anticonvulsants; Carbamazepine; Child; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Piracetam; Remission Induction; Topiramate; Triazines; Valproic Acid; Zonisamide | 2017 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2018 |
[Medicaments and oral healthcare. Proliferation of the gingiva].
Topics: Anticonvulsants; Carbamazepine; Cell Proliferation; Ethosuximide; Gingiva; Humans; Netherlands; Oral Hygiene; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 2018 |
Carbamazepine versus phenobarbitone monotherapy for epilepsy: an individual participant data review.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsies, Partial; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Randomized Controlled Trials as Topic; Recurrence; Remission Induction; Seizures; Time Factors; Treatment Failure | 2018 |
Phenobarbital rheumatism-A fresh look at an old malady: Case report and systematic review of literature.
Topics: Adult; Anticonvulsants; Antirheumatic Agents; Arthritis, Rheumatoid; Carbamazepine; Complex Regional Pain Syndromes; Diagnostic Errors; Drug Substitution; Drug Tapering; Epilepsy; Female; Humans; Phenobarbital; Predictive Value of Tests; Pregabalin; Treatment Outcome; Unnecessary Procedures | 2020 |
Antiepileptic drugs as prophylaxis for postcraniotomy seizures.
Topics: Anticonvulsants; Carbamazepine; Craniotomy; Humans; Isoxazoles; Levetiracetam; Phenobarbital; Phenytoin; Piracetam; Postoperative Complications; Randomized Controlled Trials as Topic; Seizures; Valproic Acid; Zonisamide | 2020 |
Use of Phenytoin, Phenobarbital Carbamazepine, Levetiracetam Lamotrigine and Valproate in Pregnancy and Breastfeeding: Risk of Major Malformations, Dose-dependency, Monotherapy vs Polytherapy, Pharmacokinetics and Clinical Implications.
Topics: Anticonvulsants; Breast Feeding; Carbamazepine; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2021 |
Efficacy and Safety of Phenobarbitone as First-Line Treatment for Neonatal Seizure: A Systematic Review and Meta-Analysis.
Topics: Anticonvulsants; Carbamazepine; Humans; Infant, Newborn; Phenobarbital; Phenytoin; Seizures | 2021 |
Side effects of long-term oral anti-seizure drugs on thyroid hormones in patients with epilepsy: a systematic review and network meta-analysis.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Lamotrigine; Levetiracetam; Network Meta-Analysis; Oxcarbazepine; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Topiramate; Valproic Acid | 2022 |
COVID-19 and antiepileptic drugs: an approach to guide practices when nirmatrelvir/ritonavir is co-prescribed.
Topics: Anticonvulsants; Carbamazepine; Clobazam; COVID-19 Drug Treatment; Cytochrome P-450 CYP3A Inducers; Drug Interactions; Humans; Oxcarbazepine; Pentobarbital; Phenobarbital; Phenytoin; Ritonavir; Valproic Acid | 2022 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
64 trial(s) available for phenobarbital and carbamazepine
| Article | Year |
|---|---|
[Experiences with sodium 2-propyl valerate (Depakine) in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Clinical Trials as Topic; Epilepsy; Female; Humans; Hydrocephalus; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Spasms, Infantile; Valerates; Valproic Acid | 1977 |
Sodium valproate, serum level and clinical effect in epilepsy: a controlled study.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Dimethadione; Dose-Response Relationship, Drug; Drug Evaluation; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
Paracetamol disposition in normal subjects and in patients treated with antiepileptic drugs.
Topics: Acetaminophen; Administration, Oral; Adult; Anticonvulsants; Biological Availability; Carbamazepine; Female; Humans; Injections, Intravenous; Male; Phenobarbital; Phenytoin; Primidone | 1979 |
Carbamazepine in difficult to control epileptic out-patients.
Topics: Adolescent; Adult; Ambulatory Care; Carbamazepine; Child; Child, Preschool; Clinical Trials as Topic; Drug Evaluation; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Leukocyte Count; Middle Aged; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Placebos | 1975 |
Plasma level and effect of carbamazepine in grand mal and psychomotor epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Middle Aged; Phenobarbital; Phenytoin | 1975 |
The efficacy of carbamazepine combinations in epilepsy.
Topics: Adult; Biological Availability; Carbamazepine; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Time Factors | 1975 |
A large-scale study of epilepsy in Ecuador: methodological aspects.
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Developing Countries; Ecuador; Epilepsy; Female; Humans; Incidence; Longitudinal Studies; Male; Middle Aged; Phenobarbital; Prospective Studies; Rural Population; Seizures, Febrile | 1992 |
Analyses of the pattern of therapeutic drug monitoring in a university hospital laboratory. Suitability and performance of the CEDIA assays.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Quality Control; Theophylline | 1992 |
Comprehensive primary health care antiepileptic drug treatment programme in rural and semi-urban Kenya. ICBERG (International Community-based Epilepsy Research Group)
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy; Female; Follow-Up Studies; Humans; Kenya; Male; Middle Aged; Patient Care Team; Phenobarbital; Primary Health Care; Program Evaluation; Rural Health; Urban Health | 1991 |
[Phosphorus-calcium metabolism in children under prolonged treatment with anticonvulsants. (II)].
Topics: Anticonvulsants; Calcium; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Humans; Infant; Phenobarbital; Phosphorus; Valproic Acid | 1991 |
Comparative cognitive effects of anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Random Allocation; Statistics as Topic | 1990 |
A pilot study of stiripentol, a new anticonvulsant drug, in complex partial seizures uncontrolled by carbamazepine.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Dioxolanes; Dioxoles; Drug Synergism; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Pilot Projects; Valproic Acid | 1989 |
Aspects of compliance: taking drugs and keeping clinic appointments.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Middle Aged; Multicenter Studies as Topic; Outpatient Clinics, Hospital; Patient Compliance; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1988 |
Results of a nationwide Veterans Administration Cooperative Study comparing the efficacy and toxicity of carbamazepine, phenobarbital, phenytoin, and primidone.
Topics: Adult; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1987 |
Progabide for refractory partial epilepsy: a controlled add-on trial.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Random Allocation | 1986 |
Prednisolone and methylprednisolone kinetics in children receiving anticonvulsant therapy.
Topics: Adolescent; Anticonvulsants; Asthma; Biological Availability; Carbamazepine; Child; Half-Life; Humans; Methylprednisolone; Phenobarbital; Phenytoin; Prednisolone; Research Design | 1987 |
Comparison of carbamazepine, phenobarbital, phenytoin, and primidone in partial and secondarily generalized tonic-clonic seizures.
Topics: Adolescent; Adult; Aged; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsies, Partial; Epilepsy; Erectile Dysfunction; Female; Follow-Up Studies; Humans; Leukocyte Count; Lupus Vulgaris; Lymphoma; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Psychoses, Substance-Induced | 1985 |
Carbamazepine for epilepsy. A controlled prospective evaluation.
Topics: Adult; Blood Cell Count; Bone Marrow Diseases; Carbamazepine; Clinical Trials as Topic; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Humans; Leukopenia; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Prospective Studies; Psychiatric Status Rating Scales | 1974 |
The effects of carbamazepine on patients with psychomotor epilepsy: results of a double-blind study.
Topics: Adolescent; Adult; Analysis of Variance; Behavior; Carbamazepine; Cerebral Cortex; Clinical Trials as Topic; Computers; Drug Evaluation; Electroencephalography; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Placebos; Telemetry | 1974 |
A controlled trial on Ro 5-4023 (clonazepam) in the treatment of psychomotor epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Child; Chlorobenzenes; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Fatigue; Female; Humans; Male; Middle Aged; Nitro Compounds; Phenobarbital; Phenytoin; Placebos; Primidone; Time Factors | 1973 |
Clinical evaluation of side-effects of drugs.
Topics: Accident Prevention; Aged; Anti-Bacterial Agents; Anticoagulants; Carbamazepine; Dibenzazepines; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Evaluation Studies as Topic; Female; Humans; Length of Stay; Male; Middle Aged; Migraine Disorders; Pharmaceutical Preparations; Phenobarbital; Placebos; Warfarin | 1973 |
Single drug therapy for intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy, Temporal Lobe; Humans; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1983 |
Historical perspective on the choice of antiepileptic drugs for the treatment of seizures in adults.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Epilepsy; History, 20th Century; Humans; Phenobarbital; Phenytoin; Primidone; Seizures | 1983 |
Phenobarbital compared with carbamazepine in prevention of recurrent febrile convulsions. A double-blind study.
Topics: Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Follow-Up Studies; Humans; Infant; Male; Phenobarbital; Random Allocation; Recurrence; Seizures, Febrile | 1983 |
Controlled and comparative trials of valproate performed in Europe and Asia.
Topics: Adolescent; Adult; Asia; Carbamazepine; Child; Clinical Trials as Topic; Epilepsy; Europe; Humans; Phenobarbital; Phenytoin; Seizures, Febrile; Valproic Acid | 1984 |
Influence of dextropropoxyphene on steady state serum levels and protein binding of three anti-epileptic drugs in man.
Topics: Adolescent; Adult; Aged; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Clinical Trials as Topic; Dextropropoxyphene; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 1980 |
Kinetics of phenobarbital in normal subjects and epileptic patients.
Topics: Administration, Oral; Adult; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Phenobarbital; Phenytoin | 1982 |
Phenobarbitone elimination rate after oral charcoal.
Topics: Carbamazepine; Charcoal; Half-Life; Humans; Intestinal Absorption; Phenobarbital; Phenylbutazone | 1980 |
Effects of long-term treatment with antiepileptic drugs on serum lipid levels in children with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Valproic Acid | 1995 |
[Gamma-vinyl-GABA: first experiences in Italy. II].
Topics: Adolescent; Adult; Aminocaproates; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Humans; Italy; Male; Middle Aged; Phenobarbital; Placebos; Seizures; Valproic Acid; Vigabatrin | 1994 |
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo.
Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid | 1993 |
Pharmacokinetic interaction of single doses of quinine and carbamazepine, phenobarbitone and phenytoin in healthy volunteers.
Topics: Administration, Oral; Adult; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Quinine | 1993 |
A comparison of the OPUS and TDx analysers for antiepileptic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Female; Fluorescence Polarization Immunoassay; Humans; Immunoassay; Male; Phenobarbital; Phenytoin; Regression Analysis; Reproducibility of Results; Valproic Acid | 1995 |
Activities of antioxidant enzymes and formation of the glutathione adduct of hemoglobin (Hb ASSG) in epileptic patients with long-term antiepileptic therapy.
Topics: Anticonvulsants; Antioxidants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Erythrocytes; Female; Glutathione; Hemoglobins; Humans; Male; Middle Aged; Phenobarbital; Valproic Acid | 1995 |
Randomised comparative monotherapy trial of phenobarbitone, phenytoin, carbamazepine, or sodium valproate for newly diagnosed childhood epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Prospective Studies; Treatment Outcome; Valproic Acid | 1996 |
Comparison of antiepileptic drugs on cognitive function in newly diagnosed epileptic children: a psychometric and neurophysiological study.
Topics: Adolescent; Anticonvulsants; Bender-Gestalt Test; Carbamazepine; Child; Cognition; Epilepsy; Event-Related Potentials, P300; Evoked Potentials, Auditory; Female; Humans; Male; Phenobarbital; Valproic Acid; Wechsler Scales | 1996 |
Assessment of drowsiness in epilepsy patients receiving chronic antiepileptic drug therapy.
Topics: Adult; Age Factors; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Psychiatric Status Rating Scales; Psychological Tests; Sleep Stages; Valproic Acid; Wakefulness | 1996 |
Systematic testing of medical intractability for carbamazepine, phenytoin, and phenobarbital or primidone in monotherapy for patients considered for epilepsy surgery.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clinical Protocols; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Epilepsy; Follow-Up Studies; Humans; Infant; Middle Aged; Patient Selection; Phenobarbital; Phenytoin; Primidone; Quality of Life; Treatment Failure; Treatment Outcome | 1996 |
Pharmacokinetic interactions between lamotrigine and other antiepileptic drugs in children with intractable epilepsy.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Lamotrigine; Male; Phenobarbital; Treatment Outcome; Triazines; Valproic Acid | 1996 |
Effect of enzyme inducing anticonvulsants on ethosuximide pharmacokinetics in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Enzyme Induction; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Intestinal Absorption; Male; Middle Aged; Phenobarbital; Phenytoin | 1996 |
Brainstem auditory evoked potentials in epileptics on different anti-epileptic drugs.
Topics: Acoustic Stimulation; Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Combinations; Epilepsy; Evoked Potentials, Auditory, Brain Stem; Female; Functional Laterality; Humans; Phenobarbital; Phenytoin | 1996 |
Serum concentrations of lamotrigine in epileptic patients: the influence of dose and comedication.
Topics: Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Triazines; Valproic Acid | 1996 |
Relationships between carbamazepine-diol, carbamazepine-epoxide, and carbamazepine total and free steady-state concentrations in epileptic patients: the influence of age, sex, and comedication.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Protein Binding; Sex Factors | 1996 |
Outcome evaluation of gabapentin as add-on therapy for partial seizures. "NEON" Study Investigators Group. Neurontin Evaluation of Outcomes in Neurological Practice.
Topics: Acetates; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Epilepsies, Partial; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurologic Examination; Phenobarbital; Phenytoin; Primidone; Quality of Life; Valproic Acid | 1998 |
Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study.
Topics: Acetates; Adult; Amines; Anticonvulsants; Carbamazepine; Central Nervous System Depressants; Cyclohexanecarboxylic Acids; Electric Stimulation; Ethanol; Evoked Potentials, Motor; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lorazepam; Male; Motor Cortex; Neural Inhibition; Phenobarbital; Transcranial Magnetic Stimulation; Triazines; Vigabatrin | 1998 |
Serum carnitine levels in epileptic children before and during treatment with valproic acid, carbamazepine, and phenobarbital.
Topics: Adolescent; Animals; Anticonvulsants; Carbamazepine; Carnitine; Child; Child, Preschool; Epilepsy; Humans; Infant; Phenobarbital; Statistics, Nonparametric; Valproic Acid | 1998 |
Anti-epileptic drug intake adherence. The value of the blood drug level measurement and the clinical approach.
Topics: Anticonvulsants; Carbamazepine; Cross-Sectional Studies; Drug Monitoring; Epilepsy; Female; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin | 1998 |
Does withdrawal of different antiepileptic drugs have different effects on seizure recurrence? Further results from the MRC Antiepileptic Drug Withdrawal Study.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Proportional Hazards Models; Recurrence; Risk Assessment; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1999 |
Effect of felbamate on clobazam and its metabolite kinetics in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsies, Partial; Felbamate; Female; Humans; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Prospective Studies; Triazines; Valproic Acid | 1999 |
A multicenter randomized controlled trial on the clinical impact of therapeutic drug monitoring in patients with newly diagnosed epilepsy. The Italian TDM Study Group in Epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dizziness; Drug Administration Schedule; Drug Monitoring; Epilepsy; Female; Follow-Up Studies; Headache; Humans; Male; Middle Aged; Phenobarbital; Sleep Stages; Survival Analysis; Treatment Outcome; Valproic Acid | 2000 |
Infantile spasms: diagnosis and assessment of treatment response by video-EEG.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Clobazam; Electroencephalography; Female; Humans; Infant; Infant, Newborn; Male; Oxcarbazepine; Phenobarbital; Predictive Value of Tests; Pyridoxine; Spasms, Infantile; Treatment Outcome; Video Recording; Vigabatrin | 2001 |
Add-on phenytoin fails to prevent early seizures after surgery for supratentorial brain tumors: a randomized controlled study.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Neoplasms; Craniotomy; Female; Humans; Incidence; Intraoperative Care; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Care; Risk Factors; Seizures | 2002 |
Topiramate therapeutic monitoring in patients with epilepsy: effect of concomitant antiepileptic drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Phenobarbital; Phenytoin; Prospective Studies; Topiramate; Triazines; Valproic Acid | 2002 |
Pharmacokinetic interaction between albendazole sulfoxide enantiomers and antiepileptic drugs in patients with neurocysticercosis.
Topics: Adult; Albendazole; Anthelmintics; Anticonvulsants; Area Under Curve; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Interactions; Female; Humans; Isomerism; Male; Neurocysticercosis; Phenobarbital; Phenytoin | 2002 |
Microdialysis sampling of carbamazepine, phenytoin and phenobarbital in subcutaneous extracellular fluid and subdural cerebrospinal fluid in humans: an in vitro and in vivo study of adsorption to the sampling device.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Extracellular Space; Female; Humans; Male; Microdialysis; Middle Aged; Phenobarbital; Phenytoin; Protein Binding | 2002 |
The pharmacokinetics of oxcarbazepine and its active metabolite 10-hydroxy-carbazepine in healthy subjects and in epileptic patients treated with phenobarbitone or valproic acid.
Topics: Administration, Oral; Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Male; Oxcarbazepine; Phenobarbital; Valproic Acid | 1993 |
Factors associated with poor control in partial complex epilepsy.
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy, Complex Partial; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Phenobarbital; Predictive Value of Tests; Prospective Studies; Recurrence; Risk Factors; Treatment Outcome; Triazines; Valproic Acid | 2004 |
Evolution of serum lipids and lipoprotein (a) levels in epileptic children treated with carbamazepine, valproic acid, and phenobarbital.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Diet; Epilepsy; Female; Humans; Lipids; Lipoprotein(a); Male; Phenobarbital; Time Factors; Valproic Acid | 2006 |
Effect of antiepileptic drugs on plasma lipids, lipoprotein (a), and liver enzymes.
Topics: Adolescent; Alkaline Phosphatase; Anticonvulsants; Apolipoproteins; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Infant; Lipids; Liver; Phenobarbital; Prospective Studies; Risk Factors; Time Factors; Transferases; Valproic Acid | 2006 |
Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Double-Blind Method; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Prospective Studies | 2007 |
Interaction profile of Zizyphus jujuba with phenytoin, phenobarbitone, and carbamazepine in maximal electroshock-induced seizures in rats.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Chi-Square Distribution; Chromatography, High Pressure Liquid; Cognition Disorders; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Fruit; Glutathione; Lipid Peroxidation; Male; Maze Learning; Phenobarbital; Phenytoin; Phytotherapy; Rats; Rats, Wistar; Seizures; Ziziphus | 2012 |
Quantification of the impact of enzyme-inducing antiepileptic drugs on irinotecan pharmacokinetics and SN-38 exposure.
Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Camptothecin; Carbamazepine; Drug Interactions; Enzyme Induction; Female; Glioma; Glucuronates; Humans; Irinotecan; Male; Middle Aged; Phenobarbital; Phenytoin | 2015 |
Brivaracetam population pharmacokinetics in children with epilepsy aged 1 month to 16 years.
Topics: Administration, Oral; Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Models, Biological; Nonlinear Dynamics; Phenobarbital; Pyrrolidinones; Valproic Acid | 2017 |
Influence of Inflammation on the Pharmacokinetics of Perampanel.
Topics: Adolescent; Adult; Anticonvulsants; C-Reactive Protein; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Inflammation; Male; Middle Aged; Nitriles; Phenobarbital; Phenytoin; Pyridones; Time Factors; Young Adult | 2018 |
842 other study(ies) available for phenobarbital and carbamazepine
| Article | Year |
|---|---|
Synthesis and anticonvulsant activity of enaminones.
Topics: Amines; Animals; Anticonvulsants; Drug Evaluation, Preclinical; Electric Stimulation; Kindling, Neurologic; Male; Mice; Rats; Seizures; Structure-Activity Relationship | 1992 |
Synthesis and anticonvulsant activity of imidooxy derivatives.
Topics: Animals; Anticonvulsants; Chickens; Electroshock; Imides; Indicators and Reagents; Molecular Structure; Phthalimides; Reflex; Structure-Activity Relationship; Succinimides | 1991 |
2,4-Dihydro-3H-1,2,4-triazol-3-ones as anticonvulsant agents.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Gerbillinae; Hippocampus; Hypoxia; Male; Mice; Neurons; Phencyclidine; Receptors, GABA-A; Receptors, N-Methyl-D-Aspartate; Triazoles | 1990 |
Synthesis and anticonvulsant activity of 2-benzylglutarimides.
Topics: Animals; Anticonvulsants; Benzyl Compounds; Mice; Piperidines; Piperidones; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 3. Guanidines.
Topics: Animals; Chemical Phenomena; Chemistry; Electroshock; Guanidines; Mice; Pentylenetetrazole; Rats; Seizures; Thiadiazoles | 1987 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 1. Hydrazines.
Topics: Animals; Anticonvulsants; Hydrazines; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Substituted 1,3,4-thiadiazoles with anticonvulsant activity. 2. Aminoalkyl derivatives.
Topics: Animals; Anticonvulsants; Mice; Rats; Structure-Activity Relationship; Thiadiazoles | 1986 |
Synthesis and activity of 6-aryl-3-(hydroxypolymethyleneamino)pyridazines in animal models of epilepsy.
Topics: Animals; Anticonvulsants; Bicuculline; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Female; Hypnotics and Sedatives; Kindling, Neurologic; Male; Mice; Motor Skills; Papio; Pentylenetetrazole; Photic Stimulation; Pyridazines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship | 1986 |
Synthesis and anticonvulsant activity of enaminones. 3. Investigations on 4'-, 3'-, and 2'-substituted and polysubstituted anilino compounds, sodium channel binding studies, and toxicity evaluations.
Topics: Animals; Anticonvulsants; Batrachotoxins; Kidney; Liver; Male; Mice; Rats; Rats, Inbred F344; Sodium Channels; Structure-Activity Relationship | 1995 |
Synthesis and anticonvulsant properties of new benzylpyridazine derivatives.
Topics: Animals; Anticonvulsants; Lamotrigine; Male; Mice; Molecular Conformation; Pyridazines; Structure-Activity Relationship; Triazines | 1994 |
Synthesis and CLOGP correlation of imidooxy anticonvulsants.
Topics: Animals; Anticonvulsants; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Electroshock; Male; Mice; Models, Molecular; Molecular Structure; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Seizures; Spiro Compounds; Structure-Activity Relationship | 1993 |
Synthesis and anticonvulsant activity of 2(3H)-benzoxazolone and 2(3H)-benzothiazolone derivatives.
Topics: Animals; Anticonvulsants; Electric Stimulation; Injections, Intraperitoneal; Male; Mice; Oxazoles; Rats; Seizures; Thiazoles | 1998 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Synthesis and anticonvulsant activity of 7-alkoxyl-4,5-dihydro-[1,2,4]triazolo[4,3-a]quinolines.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Mice; Neurotoxicity Syndromes; Quinolines; Seizures; Structure-Activity Relationship | 2005 |
Discovery of N-(2,6-dimethylphenyl)-substituted semicarbazones as anticonvulsants: hybrid pharmacophore-based design.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Benzamides; Chemical and Drug Induced Liver Injury; Drug Design; Female; gamma-Aminobutyric Acid; Male; Mice; Models, Molecular; Motor Activity; Rats; Seizures; Semicarbazones; Structure-Activity Relationship | 2005 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Synthesis of some novel N4-(naphtha[1,2-d]thiazol-2-yl)semicarbazides as potential anticonvulsants.
Topics: Animals; Anticonvulsants; Brain Chemistry; Glutathione Peroxidase; Malondialdehyde; Mice; Motor Activity; Rats; Seizures; Semicarbazides; Structure-Activity Relationship; Superoxide Dismutase | 2009 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Synthesis, anticonvulsant and CNS depressant activity of some new bioactive 1-(4-substituted-phenyl)-3-(4-oxo-2-phenyl/ethyl-4H-quinazolin-3-yl)-urea.
Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Depressants; Male; Mice; Molecular Structure; Pentylenetetrazole; Quinazolinones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Structure-Activity Relationship; Urea | 2009 |
SCY-635, a novel nonimmunosuppressive analog of cyclosporine that exhibits potent inhibition of hepatitis C virus RNA replication in vitro.
Topics: Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cyclophilin A; Cyclosporins; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Haplorhini; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Leukocytes, Mononuclear; Mice; Molecular Structure; Rats; RNA, Viral; Virus Replication | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Triazole incorporated thiazoles as a new class of anticonvulsants: design, synthesis and in vivo screening.
Topics: Animals; Anticonvulsants; Drug Design; Electroconvulsive Therapy; Lethal Dose 50; Mice; Triazoles | 2010 |
Synthesis and anticonvulsant activity of a new 6-alkoxy-[1,2,4]triazolo[4,3-b]pyridazine.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Mice; Molecular Structure; Motor Activity; Pyridazines; Rotarod Performance Test; Seizures; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Synthesis and anticonvulsant activity of N-3-arylamide substituted 5,5-cyclopropanespirohydantoin derivatives.
Topics: Amides; Animals; Anticonvulsants; Dose-Response Relationship, Drug; Electroshock; Hydantoins; Mice; Molecular Structure; Seizures; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Synthesis and anticonvulsant activity of 7-phenyl-6,7-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-5(4H)-ones and their derivatives.
Topics: 3-Mercaptopropionic Acid; Animals; Anticonvulsants; Bicuculline; Electroshock; Isoniazid; Mice; Pentylenetetrazole; Pyrimidinones; Seizures; Semicarbazides; Structure-Activity Relationship; Triazoles | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Synthesis and anticonvulsant activity of 1-(8-(benzyloxy)quinolin-2-yl)-6-substituted-4,6-diazaspiro[2,4]heptane-5,7-diones.
Topics: Animals; Anticonvulsants; Biological Assay; Electroshock; Heptanes; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Molecular Structure; Quinolines; Seizures; Spiro Compounds; Structure-Activity Relationship; Toxicity Tests | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Synthesis and anticonvulsant activity of ethyl 1-(2-arylhydrazinecarboxamido)-2,2-dimethylcyclopropanecarboxylate derivatives.
Topics: Animals; Anticonvulsants; Chemistry Techniques, Synthetic; Hydrazines; Male; Mice; Motor Activity; Rotarod Performance Test; Seizures | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Design, synthesis and pharmacological evaluation of N-[4-(4-(alkyl/aryl/heteroaryl)-piperazin-1-yl)-phenyl]-carbamic acid ethyl ester derivatives as novel anticonvulsant agents.
Topics: Animals; Anticonvulsants; Carbamates; Drug Design; Electroshock; Epilepsy; Mice; Pentylenetetrazole; Piperazine; Piperazines; Seizures | 2015 |
Synthesis of 2,6-dicarbethoxy-3,5-diaryltetrahydro-1,4-thiazine-1,1-dioxide derivatives as potent anticonvulsant agents.
Topics: Animals; Anticonvulsants; Crystallography, X-Ray; Cyclic S-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Models, Molecular; Molecular Structure; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Thiazines | 2015 |
Interactions between anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Humans; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Thiazines | 1975 |
Resistant transitory epilepsy in children.
Topics: Adrenocorticotropic Hormone; Anticonvulsants; Carbamazepine; Child, Preschool; Encephalomyelitis, Acute Disseminated; Epilepsy; Female; Follow-Up Studies; Humans; Male; Phenobarbital; Phenytoin; Smallpox Vaccine; Thiazines | 1976 |
Microsomal styrene mono-oxygenase and styrene epoxide hydrase activities in rats.
Topics: Animals; Brain; Carbamazepine; Epoxide Hydrolases; Female; Hydro-Lyases; Kidney; Lung; Male; Methylcholanthrene; Metyrapone; Microsomes; Microsomes, Liver; Myocardium; NAD; NADP; Organ Specificity; Oxygenases; Phenobarbital; Proadifen; Rats; Sex Factors; Spleen; Styrenes | 1976 |
Salivary levels of anticonvulsants: a practical approach to drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Saliva | 1977 |
Simultaneous measurement of phenobarbital, phenytoin, primidone, ethosuximide, and carbamazepine in serum by high-pressure liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Hot Temperature; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1977 |
Measurement of anti-epileptic drugs in plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Phenobarbital; Phenytoin; Primidone; Quality Control; Thiazines | 1977 |
The extraction of antiepileptic drugs. Model study on partition coefficients.
Topics: Anticonvulsants; Carbamazepine; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Solvents; Spectrum Analysis | 1978 |
Excretion of antiepileptic drugs in sweat.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Phenobarbital; Phenytoin; Sweat; Temperature | 1978 |
[Drug interactions in antiepileptic combination therapy].
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Thiazines; Time Factors; Urea; Valproic Acid | 1979 |
Gas-liquid chromatography of undervatized drugs after chromatographic extraction from blood.
Topics: Amobarbital; Anticonvulsants; Blood Chemical Analysis; Carbamazepine; Chromatography, Gas; Gastric Juice; Glutethimide; Humans; Hypnotics and Sedatives; Methaqualone; Phenobarbital; Phenytoin; Piperidones; Primidone; Secobarbital | 1979 |
Letter: Bioavailability of drugs after intramuscular injection.
Topics: Absorption; Administration, Oral; Adult; Biological Availability; Biotransformation; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Injections, Intramuscular; Male; Phenobarbital; Phenytoin; Primidone | 1975 |
Interactions of antiepileptic drugs.
Topics: Anti-Infective Agents; Anticonvulsants; Benzodiazepines; Biotransformation; Blood Proteins; Carbamazepine; Dextropropoxyphene; Dicumarol; Disulfiram; Drug Interactions; Ethosuximide; Humans; Intestinal Absorption; Isoniazid; Methylphenidate; Phenethylamines; Phenobarbital; Phenothiazines; Phenytoin; Primidone; Protein Binding; Thiazines | 1975 |
The medical treatment of epilepsy: antiepileptic drug interactions and teratogenicity.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Calcium; Carbamazepine; Child; Dicumarol; Digitoxin; Drug Interactions; Female; Humans; Male; Oxacillin; Phenobarbital; Phenytoin; Pregnancy; Vitamin D | 1979 |
[Blood level of antiepileptic drugs and therapeutic effect in mono- and polytherapy (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1978 |
Effect of carbamazepine, phenytoin and phenobarbitone on serum levels of thyroid hormones and thyrotropin in humans.
Topics: Adult; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Radioimmunoassay; Thyroid Hormones; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Triiodothyronine, Reverse | 1978 |
Relationships between plasma concentrations of diphenylhydantoin, phenobarbital, carbamazepine, and 3-sulfamoylmethyl-1,2-benzisoxazole (AD-810), a new anticonvulsant agent, and their anticonvulsant or neurotoxic effects in experimental animals.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Dogs; Dose-Response Relationship, Drug; Haplorhini; Isoxazoles; Male; Mice; Motor Skills; Oxazoles; Phenobarbital; Phenytoin; Rabbits; Rats; Seizures; Species Specificity | 1979 |
[The influence of carbamazepine and clonazepam on UDP-glucuronyltransferase activity].
Topics: Animals; Benzodiazepinones; Carbamazepine; Clonazepam; Glucuronosyltransferase; In Vitro Techniques; Liver; Methylcholanthrene; Phenobarbital; Rats | 1979 |
Bone mineral content in epileptics.
Topics: Aged; Bone and Bones; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Minerals; Muscle Contraction; Muscle Tonus; Osteomalacia; Phenobarbital; Phenytoin | 1979 |
Effect of convulsions and anticonvulsive drugs on cerebrospinal fluid cyclic AMP in rabbits.
Topics: Animals; Aspartate Aminotransferases; Carbamazepine; Cyclic AMP; Depression, Chemical; Female; Male; Phenobarbital; Phenytoin; Rabbits; Seizures | 1976 |
Prophylactic effects of phenytoin, phenobarbital, and carbamazepine examined in kindling cat preparations.
Topics: Animals; Carbamazepine; Cats; Disease Models, Animal; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsy; Male; Phenobarbital; Phenytoin; Seizures; Synaptic Transmission | 1976 |
Cyclic AMP accumulation in cerebral cortical slices: effect of carbamazepine, phenobarbital, and phenytoin.
Topics: Adenosine; Animals; Brain Chemistry; Carbamazepine; Cyclic AMP; Female; In Vitro Techniques; Norepinephrine; Ouabain; Phenobarbital; Phenytoin; Rats | 1977 |
Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Clonazepam; Cyclic AMP; Diazepam; Dopamine; Male; Norepinephrine; Phenobarbital; Phenytoin; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Rats | 1979 |
Anticonvulsant drug actions on in vitro and in vivo levels of cyclic AMP in the mouse brain.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Carbamazepine; Cerebellum; Cerebral Cortex; Clonazepam; Culture Techniques; Cyclic AMP; Diazepam; Male; Mice; Norepinephrine; Ouabain; Pentylenetetrazole; Phenobarbital; Phenytoin; Potassium; Premedication; Seizures | 1979 |
Organic nitrogen-selective detector used in gas-chromatographic determination of some anticonvulsant and barbiturate drugs in plasma and tissues.
Topics: Animals; Anticonvulsants; Barbiturates; Brain Chemistry; Carbamazepine; Chromatography, Gas; Horses; Humans; Hydantoins; Methods; Nitrogen; Phenobarbital; Phenytoin; Primidone; Time Factors | 1975 |
A primate model for testing anticonvulsant drugs.
Topics: Allyl Compounds; Animals; Anticonvulsants; Carbamazepine; Chromatography, Gas; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Evaluation, Preclinical; Electroencephalography; Ethosuximide; Female; Glycine; Male; Myoclonus; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Primidone; Seizures; Thiazines | 1975 |
[Effects of combination of anti-epileptic drugs].
Topics: Adrenergic beta-Antagonists; Anticonvulsants; Benzodiazepines; Carbamazepine; Digitoxin; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Lithium; Phenobarbital; Phenytoin; Primidone; Thiazines; Tolbutamide; Tranquilizing Agents | 1975 |
Drug interactions during anticonvulsant therapy in childhood: diphenylhydantoin, primidone, phenobarbitone, clonazepam, nitrazepam, carbamazepin and dipropylacetate.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Nitrazepam; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1977 |
Epilepsy and IgA deficiency--the effect of sodium valproate.
Topics: Adult; Agammaglobulinemia; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin A; Male; Phenobarbital; Phenytoin; Valerates; Valproic Acid | 1977 |
A comparative study of the efficacy of newer antiepiletpic drugs on experimentally-induced febrile convulsions.
Topics: Animals; Anticonvulsants; Body Temperature; Carbamazepine; Clonazepam; Male; Mice; Phenobarbital; Seizures; Seizures, Febrile; Valproic Acid | 1977 |
Choice of drug therapy in epilepsy.
Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin; Valproic Acid | 1977 |
[Plasma levels of anticonvulsants. Experiences with routine plasma level determination of 6 different anticonvulsants].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1978 |
Distribution of plasma carbamazepine in epileptic patients.
Topics: Adolescent; Adult; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Phenobarbital | 1977 |
Effect of anticonvulsants on thalamic afterdischarge in rats and cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Male; Phenobarbital; Phenytoin; Rats; Thalamus; Trimethadione; Valproic Acid | 1977 |
Long-term use of the major anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Time Factors; Valproic Acid | 1978 |
A micromethod for simultaneous estimation of blood levels of some commonly used antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Diazepam; Humans; Microchemistry; Nordazepam; Phenobarbital; Phenytoin | 1978 |
Consecutive gas chromatographic determination of phenytoin, phenobarbital, primidone, phenylethylmalondiamide, carbamazepine, trimethadione, dimethadione, ethosuximide, and valproate from the same serum specimen.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Dimethadione; Ethosuximide; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Trimethadione; Valproic Acid | 1978 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Status Epilepticus; Valproic Acid | 1979 |
Study of the EMIT method for determination of anti-epileptic drugs in serum using an LKB 2086 reaction rate analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1978 |
Effect of anticonvulsants on spiking activity induced by cortical freezing in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Arousal; Carbamazepine; Cats; Diazepam; Electrocardiography; Electroencephalography; Female; Freezing; Gallamine Triethiodide; Immobilization; Male; Phenobarbital; Phenytoin; Taurine; Trimethadione; Valproic Acid; Visual Cortex | 1979 |
Valproic acid binding to human serum albumin and determination of free fraction in the presence of anticonvulsants and free fatty acids.
Topics: Anticonvulsants; Carbamazepine; Fatty Acids, Nonesterified; Humans; Linoleic Acids; Oleic Acids; Palmitic Acids; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Stearic Acids; Valproic Acid | 1979 |
Recent advances in drug therapy for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Evaluation of automated enzyme immunoassays for five anticonvulsants and theophylline adapted to a centrifugal analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1979 |
The use of antiepileptic drugs.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Drug Interactions; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1979 |
Anticonvulsant therapy in childhood. Recent advances.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1979 |
[The serum concentration of anticonvulsants -- pharmacokinetic findings and practical therapeutic applications (author's transl)].
Topics: Antacids; Anticonvulsants; Biological Availability; Carbamazepine; Chromatography, Gas; Clonazepam; Dosage Forms; Ethosuximide; Half-Life; Humans; Immunoenzyme Techniques; Intestinal Absorption; Phenobarbital; Phenytoin; Primidone; Seizures; Valproic Acid | 1979 |
Accuracy of serum anticonvulsant measurements. A comparison of enzyme multiplied immunoassay technique and gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1979 |
High pressure liquid chromatography for simultaneous analysis of anticonvulsants: comparison with EMIT system.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Immunoenzyme Techniques; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1979 |
Distribution of anticonvulsant drugs in gray and white matter of human brain.
Topics: Anticonvulsants; Brain; Carbamazepine; Epilepsies, Partial; Humans; Mesencephalon; Nervous System; Phenobarbital; Phenytoin; Spinal Cord | 1977 |
Effect of anticonvulsants on cortical focal seizure in cats.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Cats; Diazepam; Electrocardiography; Epilepsies, Partial; Female; Heart; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione; Valproic Acid | 1977 |
Mental dullness associated with left frontal continuous focal discharge.
Topics: Adult; Carbamazepine; Cognition Disorders; Electroencephalography; Epilepsy, Post-Traumatic; Frontal Lobe; Humans; Male; Phenobarbital; Phenytoin; Syndrome | 1977 |
Medical treatment of epilepsy: part I.
Topics: Anticonvulsants; Bromides; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Female; Humans; Infant; Phenobarbital; Phenytoin; Recurrence | 1978 |
Anticonvulsant therapy. Approaches to some common clinical problems.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Pregnancy; Seizures; Seizures, Febrile | 1979 |
[Significance of pharmacogenic liver reactions for metabolism of endogenous and exogenous substances].
Topics: Carbamazepine; Diazepam; Drug-Related Side Effects and Adverse Reactions; Female; Fenoterol; Humans; Liver; Phenobarbital; Phenytoin; Pregnancy; Primidone | 1979 |
Serum anticonvulsant monitoring by liquid chromatography with a methanolic mobile phase.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1979 |
[Neutropenia in epilepsy patients].
Topics: Adolescent; Adult; Agranulocytosis; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Leukopenia; Male; Middle Aged; Neutropenia; Phenobarbital; Primidone | 1979 |
Biochemical variables related to calcium metabolism in epileptics.
Topics: Aged; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphates; Primidone | 1979 |
Mucocutaneous eruptions due to antiepileptic drug therapy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Erythema Multiforme; Female; Humans; Male; Mephenytoin; Phenobarbital; Phenytoin; Primidone; Stevens-Johnson Syndrome | 1979 |
Serum phenytoin, phenobarbital, carbamazepine, albumin; and plasma estradiol, progesterone concentrations during the menstrual cycle in women with epilepsy.
Topics: Adult; Carbamazepine; Epilepsy; Estradiol; Female; Humans; Menstruation; Phenobarbital; Phenytoin; Progesterone; Serum Albumin | 1979 |
[Drug therapy of epilepsy with control of the serum level of anti-epileptic agents].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1979 |
Monitoring saliva anticonvulsant levels in children.
Topics: Anticonvulsants; Carbamazepine; Child; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1979 |
Interictal acute psychoses in temporal lobe epilepsy during withdrawal of anticonvulsant therapy.
Topics: Adult; Carbamazepine; Clonazepam; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Female; Humans; Male; Phenobarbital; Psychoses, Substance-Induced; Substance Withdrawal Syndrome | 1979 |
Tears as the best practical indicator of the unbound fraction of an anticonvulsant drug.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Phenobarbital; Protein Binding; Tears | 1979 |
Pharmacokinetic and pharmacodynamic tolerance of a new anticonvulsant agent (3-sulfamoylmethyl-1,2-benzisoxazole) compared to phenobarbital, diphenylhydantoin and carbamazepine in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Hexobarbital; Isoxazoles; Kinetics; Male; Oxazoles; Phenobarbital; Phenytoin; Proadifen; Rats; Sleep; Time Factors | 1979 |
[Studies on the serum levels of the antiepileptic drugs-with particular reference to diphenylhydantoin, phenobarbital and carbamazepine-(author's transl)].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin | 1979 |
[Studies on the separation and photometric determination of antiepileptics (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Mephobarbital; Methods; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet | 1979 |
Effect of anticonvulsants on plasma testosterone and sex hormone binding globulin levels.
Topics: Anticonvulsants; Carbamazepine; Epilepsy, Temporal Lobe; Female; Humans; Liver; Male; Phenobarbital; Phenytoin; Sex Factors; Sex Hormone-Binding Globulin; Testosterone | 1978 |
Simultaneous gas chromatographic analysis for the seven commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1977 |
[Determination of drug-albumin binding in buffered bovine serum albumin solutions applying a modified ultrafiltration process (author's transl)].
Topics: Animals; Carbamazepine; Cattle; Chlorpromazine; Methods; Pharmaceutical Preparations; Phenobarbital; Phenprocoumon; Protein Binding; Serum Albumin, Bovine; Ultrafiltration | 1979 |
Therapeutic monitoring of anticonvulsant drugs in psychiatric patients: rapid, simultaneous gas-chromatographic determination of six commonly used anticonvulsants without interference from other drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1978 |
Interaction between carbamazepine and propoxyphene in man.
Topics: Adolescent; Adult; Carbamazepine; Dextropropoxyphene; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Trigeminal Neuralgia | 1977 |
[Selected clinical aspects of routine monitoring of anticonvulsant concentrations in serum (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Chromatography, Gas; Drug Therapy, Combination; Ethosuximide; Humans; Middle Aged; Phenobarbital; Phenylethylmalonamide; Phenytoin | 1977 |
[A study on anticonvulsant level in body fluid. Ist report: serum level and drug interaction (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
Factors influencing plasma carbamazepine concentrations.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Child, Preschool; Drug Interactions; Female; Humans; Infant; Infant, Newborn; Male; Mephobarbital; Middle Aged; Phenobarbital; Phenytoin | 1977 |
Kinetics of carbamazepine and carbamazepine-epoxide, determined by use of plasma and saliva.
Topics: Adolescent; Adult; Carbamazepine; Drug Interactions; Epoxy Compounds; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Saliva | 1978 |
The toxicity of the major anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1978 |
[Application of hplc-techniques to gel filtration in the determination of drug albumin binding (author's transl)].
Topics: Animals; Carbamazepine; Cattle; Chlorpromazine; Chromatography, Gel; Chromatography, High Pressure Liquid; Phenobarbital; Protein Binding; Serum Albumin, Bovine | 1978 |
[Optimizing the therapeutic process in long-term antiepileptic therapy through the determination of drug levels in patients].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy; Epilepsy; Ethosuximide; Germany, East; Humans; Methods; Phenobarbital; Phenytoin | 1978 |
Anticonvulsants and thyroid function.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Thyroid Hormones; Thyrotropin; Thyroxine; Triiodothyronine | 1978 |
[A study on anticonvulsant level in body fluids. 2nd report: Dialyzed serum (free form), CSF and saliva level (author's transl)].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Saliva | 1978 |
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Simultaneous gas chromatographic determination of diphenylhydantoin, carbamazepin (Tegretol), phenobarbital and primidone in presence of Kemadrin (procyclidine) and Prolixin (fluphenazine) in plasma of psychiatric patients.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Fluphenazine; Humans; Mental Disorders; Methods; Phenobarbital; Phenytoin; Primidone; Procyclidine; Pyrrolidines | 1978 |
Simultaneous determination of diphenylhydantoin, mephobarbital, carbamazepine, phenobarbital and primidone in serum using direct chemical ionization mass spectrometry.
Topics: Anticonvulsants; Carbamazepine; Computers; Evaluation Studies as Topic; Humans; Mass Spectrometry; Mephobarbital; Methods; Palmitic Acids; Phenobarbital; Phenytoin; Primidone | 1978 |
Seizure susceptibility and anticonvulsant activity of carbamazepine, diphenylhydantoin and phenobarbital in rats with selective depletions of brain monoamines.
Topics: Animals; Anticonvulsants; Biogenic Amines; Brain; Carbamazepine; Electroshock; Female; Hydroxydopamines; Phenobarbital; Phenytoin; Rats; Seizures | 1978 |
Improved gas-chromatographic analysis for anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards | 1978 |
Kinetics of drug interactions in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Ethanol; Female; Humans; Kinetics; Male; Phenobarbital; Phenytoin; Pregnancy; Primidone; Salicylates | 1978 |
[Neonatal abstinence syndrome in children whose mothers were treated for epilepsy during pregnancy].
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Phenobarbital; Pregnancy; Pregnancy Complications; Substance Withdrawal Syndrome | 1978 |
Greater reliability of tear versus saliva anticonvulsant levels.
Topics: Carbamazepine; Child; Humans; Phenobarbital; Saliva; Tears | 1978 |
Brain concentrations of carbamazepine and carbamazepine-10,11-epoxide in epileptic patients.
Topics: Adolescent; Brain; Carbamazepine; Child; Epilepsy; Epoxy Compounds; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1978 |
Carbamazepine levels in pregnancy and lactation.
Topics: Adult; Carbamazepine; Epilepsy, Temporal Lobe; Female; Fetal Blood; Fetus; Humans; Lactation; Milk, Human; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone | 1979 |
[Simultaneous determination of antiepileptic drugs in clinical laboratories: Problems of quality control and standardization (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenytoin; Primidone; Quality Control | 1979 |
[Measurement of the blood concentration of antiepileptic drugs. II Special cases].
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1975 |
Proposals on antiepileptic pharmacotherapy for use in developing countries.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Developing Countries; Diazepam; Epilepsy; Ethosuximide; Humans; Infant; Phenobarbital; Phenytoin; Valproic Acid | 1976 |
Seizures in adolescents.
Topics: Adolescent; Anticonvulsants; Automobile Driving; Benzodiazepines; Carbamazepine; Diagnosis, Differential; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Ethosuximide; Female; Humans; Hysteria; Male; Phenobarbital; Phenytoin; Physical Exertion; Pregnancy; Primidone; Psychology, Adolescent | 1975 |
Sensible prescribing. XI.--Juvenile and adult epilepsy.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Clonazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1975 |
Acute anticonvulsant effects of diphenylhydantoin, phenobarbital, and carbamazepine: a combined electroclinical and serum level study in amygdaloid kindled cats and baboons.
Topics: Amygdala; Animals; Carbamazepine; Cats; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electric Stimulation; Haplorhini; Light; Male; Papio; Phenobarbital; Phenytoin; Seizures; Time Factors | 1976 |
[Epileptic seizures with psychomotor symptoms and generalized spike-wave-pattern].
Topics: Adolescent; Adult; Carbamazepine; Child; Diagnosis, Differential; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Female; Humans; Male; Phenobarbital; Primidone; Psychomotor Disorders; Succinimides | 1976 |
Anticonvulsant drug antagonism of delta9tetrahydrocannabinol-induced seizures in rabbits.
Topics: Animals; Anticonvulsants; Cannabidiol; Cannabinol; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Dronabinol; Ethosuximide; Female; Male; Phenobarbital; Phenytoin; Rabbits; Seizures; Time Factors | 1977 |
Evaluation of a rapid gas-chromatographic method for the simultaneous quantitative determination of ethosuximide, phenyletheylmalonediamide, carbamazepine, phenobarbital, primidone and diphenylhydantoin in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Evaluation Studies as Topic; Humans; Methods; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1977 |
A comparison of the teratogenic activity of the antiepileptic drugs carbamazepine, clonazepam, ethosuximide, phenobarbital, phenytoin, and primidone in mice.
Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Female; Fetus; Lethal Dose 50; Maternal-Fetal Exchange; Mice; Phenobarbital; Phenytoin; Pregnancy; Primidone; Teratogens | 1977 |
Lack of effect of clonazepam on serum levels of diphenylhydantoin, phenobarbital and carbamazepine.
Topics: Adolescent; Adult; Benzodiazepinones; Carbamazepine; Child; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1977 |
The effect of anticonvulsant drugs which induce liver microsomal enzymes on derived and ingested phenobarbitone levels.
Topics: Adolescent; Adult; Biotransformation; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1977 |
[The anti-epileptic drugs].
Topics: Age Factors; Anticonvulsants; Carbamazepine; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Effects of phenytoin on the release of 14C-adenine derivatives.
Topics: Adenine; Animals; Astrocytoma; Brain Neoplasms; Carbamazepine; Cells, Cultured; Cerebral Cortex; Hypoxanthines; In Vitro Techniques; Inosine; Neuroblastoma; Ouabain; Phenobarbital; Phenytoin; Rats; Veratridine | 1977 |
Comparison of six procedures for the simultaneous determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1977 |
Simultaneous high-pressure liquid-chromatographic determination of some anticonvulsants in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Succinimides | 1976 |
Effect of 2 br-alpha-ergocryptin (CB 154) on serum prolactin and the clinical picture in a case of progressive gigantomastia in pregnancy.
Topics: Adult; Breast Diseases; Bromocriptine; Carbamazepine; Diazepam; Epilepsy, Temporal Lobe; Ergolines; Female; Humans; Mephenytoin; Phenobarbital; Pregnancy; Pregnancy Complications; Prolactin | 1976 |
Further observations on carbamazepine plasma levels in epileptic patients. Relationships with therapeutic and side effects.
Topics: Adult; Age Factors; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Phenobarbital; Phenytoin | 1976 |
High-speed liquid chromatographic determination of antiepileptic drugs in human plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin | 1976 |
Quantitative determination of underivatized anti-convulsant drugs by high resolution gas chromatography with support-coated open tubular columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Improved method for measurement of serum levels of phenobarbital, carbamazepine, primidone and diphenylhydantoin by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Drug stimulated biotransformation of hormonal steroid contraceptives: clinical implications.
Topics: Ampicillin; Biotransformation; Carbamazepine; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Drug Interactions; Enzyme Induction; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Uterine Hemorrhage | 1976 |
Simultaneous gas chromatographic analysis for the four commonly used antiepileptic drugs in serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ion Exchange Resins; Phenobarbital; Phenytoin; Primidone; Temperature | 1976 |
Anticonvulsant drugs and mental symptoms: a review.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Folic Acid Deficiency; Humans; Mental Disorders; Phenobarbital; Phenytoin; Psychoses, Substance-Induced; Schizophrenia | 1976 |
Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebellar Diseases; Chorea; Dyskinesia, Drug-Induced; Extremities; Facial Muscles; Female; Humans; Male; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Syndrome; Tranquilizing Agents; Tremor | 1976 |
Clinical pharmacokinetics in infants and children.
Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline | 1976 |
Letter: Epanutin and isoniazid interaction.
Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Epilepsy; Ethambutol; Ethosuximide; Female; Humans; Isoniazid; Phenobarbital; Phenytoin; Rifampin | 1975 |
Anticonvulsant level in saliva, serum, and cerebrospinal fluid.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone; Saliva | 1975 |
Photically induced epilepsy in Papio papio as a model for drug studies.
Topics: Acetylcholine; Animals; Carbamazepine; Clonazepam; Diazepam; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy; gamma-Aminobutyric Acid; Glycine; Humans; Norepinephrine; Papio; Phenobarbital; Phenytoin; Photic Stimulation; Serotonin; Spasms, Infantile | 1975 |
Absorption and distribution of antiepileptic drugs.
Topics: Administration, Oral; Animals; Anticonvulsants; Capsules; Carbamazepine; Female; Humans; Injections, Intramuscular; Intestinal Absorption; Maternal-Fetal Exchange; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Pregnancy; Suppositories; Tablets, Enteric-Coated; Time Factors | 1975 |
[Current viewpoints in drug treatment of epilepsy, with reference to the most common drugs in current use].
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Trimethadione | 1975 |
Depression of immune competence by phenytoin and carbamazepine. Studies in vivo and in vitro.
Topics: Adolescent; Adult; Aged; Antibodies, Bacterial; Antibody Formation; Carbamazepine; Depression, Chemical; DNA; Dose-Response Relationship, Drug; Female; Humans; Hypersensitivity, Delayed; Immunoglobulin A; Immunosuppression Therapy; Lectins; Leukocyte Count; Leukocytes; Lymphocyte Activation; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Biosynthesis; RNA; Salmonella typhi; Sex Factors; Tetanus Toxoid | 1975 |
Psychosocial management of patients with complex partial seizures.
Topics: Adult; Alcoholism; Carbamazepine; Delivery of Health Care; Drug Administration Schedule; Epilepsy; Epilepsy, Temporal Lobe; Female; Fluphenazine; Humans; Male; Mental Disorders; Middle Aged; Neurocognitive Disorders; Patient Acceptance of Health Care; Phenobarbital; Phenytoin; Schizophrenia; Social Environment; Social Problems; Socioeconomic Factors; Syndrome | 1975 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Diazepam; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Trimethadione | 1976 |
Simultaneous gas-chromatographic analysis for phenobarbital, diphenylhydantoin, carbamazepine, and primidone in serum.
Topics: Carbamazepine; Chromatography, Gas; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone; Time Factors | 1976 |
Rapid micromethod for measuring anticonvulsant drugs in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Ethosuximide; Evaluation Studies as Topic; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1976 |
Effects of epilepsy on daily functioning in northern Ecuador: summary of findings of a population-based research project.
Topics: Activities of Daily Living; Adaptation, Psychological; Adolescent; Adult; Carbamazepine; Cross-Sectional Studies; Developing Countries; Ecuador; Epilepsy; Female; Health Knowledge, Attitudes, Practice; Humans; Incidence; Male; Phenobarbital; Prospective Studies; Rural Population; Sick Role; Social Adjustment | 1992 |
Peripheral neuropathy caused by antiepileptic drugs. Neurophysiological study of the A delta and C fibers.
Topics: Adolescent; Adult; Aged; Carbamazepine; Cold Temperature; Hot Temperature; Humans; Middle Aged; Nerve Fibers; Nerve Fibers, Myelinated; Peripheral Nervous System Diseases; Phenobarbital | 1992 |
Effects of phenobarbital, carbamazepine and a combination of both on corazol-induced changes in the bioelectric activity of rat brains.
Topics: Animals; Brain; Carbamazepine; Electroencephalography; Epilepsy; Male; Pentylenetetrazole; Phenobarbital; Rats; Rats, Wistar | 1992 |
Changes in the behavioral reactions of experimental animals after repeated treatment and withdrawal of a combination of phenobarbital and carbamazepine.
Topics: Animals; Behavior, Animal; Carbamazepine; Drug Interactions; Male; Motor Activity; Orientation; Phenobarbital; Rats; Rats, Wistar | 1992 |
Phenobarbital exacerbation of self-injurious behavior.
Topics: Acute Disease; Adult; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Intellectual Disability; Male; Phenobarbital; Seizures; Self-Injurious Behavior | 1992 |
Effects of lesions of the central nucleus of the amygdala on anxiety-like behaviors in the rat.
Topics: Amygdala; Animals; Anxiety; Behavior, Animal; Carbamazepine; Chlordiazepoxide; Conditioning, Operant; Drinking Behavior; Female; Phenobarbital; Rats; Rats, Sprague-Dawley | 1992 |
Cerebral cavernous angioma: a potentially benign condition? Successful treatment in 16 cases.
Topics: Adolescent; Adult; Angiography; Brain Neoplasms; Carbamazepine; Cerebral Hemorrhage; Child; Epilepsy; Female; Hemangioma, Cavernous; Humans; Magnetic Resonance Imaging; Male; Phenobarbital; Phenytoin; Retrospective Studies; Seizures; Valproic Acid | 1992 |
The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver microsomes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Hydrocortisone; Immunoblotting; Male; Mice; Mice, Inbred CBA; Microsomes, Liver; Norpregnenes; Phenobarbital | 1992 |
"An analysis of epileptic patients nonresponsive to drugs".
Topics: Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Treatment Failure | 1992 |
Cognitive effects of antiepileptic drug discontinuation.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cognition; Cognition Disorders; Epilepsy; Humans; Middle Aged; Neuropsychological Tests; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 1992 |
Age dependency of the susceptibility of rats to aminooxyacetic acid seizures.
Topics: Aging; Aminooxyacetic Acid; Animals; Anticonvulsants; Body Temperature; Brain; Carbamazepine; Clonazepam; Disease Susceptibility; Electroencephalography; Female; gamma-Aminobutyric Acid; Glutamate Decarboxylase; Male; Organ Specificity; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Time Factors; Valproic Acid | 1992 |
Interactions between clobazam and standard antiepileptic drugs in patients with epilepsy.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1992 |
Rapid and sensitive liquid chromatographic assay of mefenamic acid in plasma.
Topics: Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Hydrogen-Ion Concentration; Indomethacin; Ketoprofen; Least-Squares Analysis; Mefenamic Acid; Phenobarbital; Phenytoin; Salicylates; Salicylic Acid; Sensitivity and Specificity; Valproic Acid | 1992 |
Effects of four common anticonvulsants on the high pressure nervous syndrome in the rat.
Topics: Animals; Carbamazepine; Diazepam; Drug Evaluation, Preclinical; High Pressure Neurological Syndrome; Male; Phenobarbital; Phenytoin; Premedication; Rats; Rats, Inbred Strains | 1992 |
Tolerance to the anticonvulsant effects of phenobarbital, trimethadione, and clonazepam in kindled rats: cross tolerance to carbamazepine.
Topics: Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Drug Tolerance; Electrodes, Implanted; Electroshock; Kindling, Neurologic; Male; Pentylenetetrazole; Phenobarbital; Rats; Seizures; Stereotaxic Techniques; Trimethadione | 1992 |
Detection of an autoantibody directed against human liver microsomal protein in a patient with carbamazepine hypersensitivity.
Topics: Adolescent; Animals; Autoantibodies; Carbamazepine; Cell Death; Chemical and Drug Induced Liver Injury; Cytosol; Drug Hypersensitivity; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; In Vitro Techniques; Leukocytes, Mononuclear; Male; Mice; Microsomes, Liver; Phenobarbital; Proteins; Rats | 1992 |
Glutathione adduct of hemoglobin (Hb ASSG) in hemolysates of patients on long-term antiepileptic therapy.
Topics: Carbamazepine; Epilepsy; Female; Glutathione; Glycated Hemoglobin; Humans; Isoelectric Focusing; Isoelectric Point; Male; Methemoglobin; Phenobarbital; Sulfhydryl Compounds | 1992 |
The syndrome of partial seizures in infancy.
Topics: Brain; Carbamazepine; Child, Preschool; Electroencephalography; Epilepsies, Partial; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Risk Factors | 1992 |
Spectrum of neural-tube defects in 34 infants prenatally exposed to antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Neural Tube Defects; Phenobarbital; Pregnancy; Pregnancy Complications; Valproic Acid | 1992 |
Antiepileptic drug disposition during pregnancy.
Topics: Adult; Anticonvulsants; Carbamazepine; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1992 |
Antiepileptics and the development of congenital anomalies.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Apgar Score; Birth Weight; Carbamazepine; Epilepsy; Female; Fetus; Gestational Age; Head; Humans; Hydantoins; Infant; Infant, Newborn; Phenobarbital; Pregnancy; Pregnancy Complications; Primidone; Syndrome; Valproic Acid | 1992 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1992 |
An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro.
Topics: Animals; Ascorbic Acid; Biotransformation; Carbamazepine; Cell Death; Cytosol; Epoxide Hydrolases; Glutathione; Humans; Ketoconazole; Lymphocytes; Mice; Microsomes, Liver; Models, Chemical; Phenobarbital; Proteins | 1992 |
Effects of long-term anticonvulsant therapy on copper, zinc, and magnesium in hair and serum of epileptics.
Topics: Adult; Anticonvulsants; Carbamazepine; Copper; Drug Therapy, Combination; Epilepsy, Generalized; Female; Hair; Humans; Long-Term Care; Magnesium; Male; Middle Aged; Phenobarbital; Phenytoin; Schizophrenia; Valproic Acid; Zinc | 1992 |
Automated homogeneous liposome immunoassay systems for anticonvulsant drugs.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Fluorescence Polarization Immunoassay; Glucosephosphate Dehydrogenase; Humans; Immunoassay; Immunoenzyme Techniques; Liposomes; Phenobarbital; Phenytoin; Quality Control; Spectrophotometry | 1992 |
Anticonvulsant drug potentiation by glycine in maximal electroshock seizures is mimicked by D-serine and antagonized by 7-chlorokynurenic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Glycine; Kynurenic Acid; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Serine | 1991 |
Influence of antiepileptic drugs on sleep patterns.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Brain; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Long-Term Care; Male; Phenobarbital; Phenytoin; Retrospective Studies; Sleep Deprivation; Sleep Stages; Valproic Acid | 1991 |
Balance and cognitive impairment in two epileptic patients before and after vagal nerve stimulation.
Topics: Adult; Carbamazepine; Cognition; Electric Stimulation Therapy; Epilepsy, Temporal Lobe; Humans; Male; Parkinson Disease; Phenobarbital; Phenytoin; Postural Balance; Reaction Time; Time Factors; Vagus Nerve; Valproic Acid | 1991 |
Familial occurrence of hypersensitivity to phenytoin.
Topics: Adult; Animals; Carbamazepine; Drug Hypersensitivity; Female; Humans; In Vitro Techniques; Mice; Phenobarbital; Phenytoin | 1991 |
Performance of fluorescence polarisation immunoassay reagents for carbamazepine, phenytoin, phenobarbitone, primidone, and valproic acid on a Cobas Fara II analyser.
Topics: Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Primidone; Reference Standards; Valproic Acid | 1991 |
Clinical evaluation of five therapeutic drugs using dry film multilayer technology on the OPUS immunoassay system.
Topics: Carbamazepine; Evaluation Studies as Topic; Humans; Immunoassay; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Reference Standards; Sensitivity and Specificity; Theophylline; Valproic Acid | 1991 |
[Evaluation of the effectiveness of monotherapy in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Drug Evaluation; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Generalized pustulation as a manifestation of the anticonvulsant hypersensitivity syndrome.
Topics: Adult; Carbamazepine; Cross Reactions; Drug Eruptions; Facial Dermatoses; Humans; Male; Middle Aged; Neutrophils; Phenobarbital; Phenytoin; Pruritus; Scalp Dermatoses; Skin Diseases, Vesiculobullous; Syndrome; Urticaria | 1991 |
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid | 1991 |
Liver damage in long-term anticonvulsant therapy: a serological and histological study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Combinations; Female; Humans; Isoantigens; Liver; Liver Diseases; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Valproic Acid | 1991 |
Plasma uric acid in patients receiving anticonvulsant monotherapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenobarbital; Phenytoin; Prospective Studies; Uric Acid; Valproic Acid | 1991 |
Short-term effects of administration of anticonvulsant drugs on free carnitine and acylcarnitine in mouse serum and tissues.
Topics: Animals; Anticonvulsants; Carbamazepine; Carnitine; Heart; In Vitro Techniques; Male; Mice; Muscles; Myocardium; Phenobarbital; Phenytoin; Prohibitins; Valproic Acid | 1991 |
Alteration of renal carnitine metabolism by anticonvulsant treatment.
Topics: Ammonia; Animals; Anticonvulsants; Carbamazepine; Carnitine; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
[Effects of antiepileptic drugs on delivery and early childhood--comparison among mono-therapies of valproic acid, phenytoin, carbamazepine and phenobarbital].
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Birth Weight; Carbamazepine; Embryonic and Fetal Development; Epilepsy; Female; Heart Defects, Congenital; Humans; Infant, Newborn; Labor, Obstetric; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Spinal Dysraphism; Valproic Acid | 1991 |
Impaired water homeostasis following mixed carbamazepine and phenobarbital overdose.
Topics: Adult; Body Water; Carbamazepine; Female; Homeostasis; Humans; Osmolar Concentration; Phenobarbital; Seizures; Water-Electrolyte Balance | 1991 |
Antiepileptogenic effects of conventional anticonvulsants in the kindling model of epilespy.
Topics: Action Potentials; Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Epilepsy; Kindling, Neurologic; Male; Phenobarbital; Rats; Rats, Inbred Strains; Valproic Acid | 1991 |
Reduction of serum carnitine concentrations during anticonvulsant therapy with phenobarbital, valproic acid, phenytoin, and carbamazepine in children.
Topics: Analysis of Variance; Carbamazepine; Carnitine; Child; Drug Combinations; Fatty Acids; Fatty Acids, Volatile; Humans; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1991 |
Epileptic patients refractory to drug therapy.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin G; Immunoglobulins; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Effect of selective bilateral destruction of the substantia nigra on antiepileptic drug actions in kindled rats.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Diazepam; Electrodes; Female; gamma-Aminobutyric Acid; Ibotenic Acid; Kindling, Neurologic; Phenobarbital; Rats; Rats, Inbred Strains; Substantia Nigra; Synaptic Transmission; Valproic Acid | 1990 |
Synthesis of mixed-functional-phase silica supports for liquid chromatography and their applications to assays of drugs in serum.
Topics: Carbamazepine; Chromatography, Liquid; Humans; Phenobarbital; Phenytoin; Silicon Dioxide | 1990 |
Antiepileptic medication in pregnancy: late effects on the children's central nervous system development.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Central Nervous System; Child; Child Development; Epilepsy; Female; Humans; Phenobarbital; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Regression Analysis; Skull | 1991 |
An ultrafiltrate of saliva collected in situ as a biological sample for diagnostic evaluation.
Topics: Carbamazepine; Humans; Phenobarbital; Phenytoin; Saliva; Specimen Handling; Ultrafiltration | 1991 |
Seizures: introduction and commentary.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1991 |
Kindling from stimulation of a highly sensitive locus in the posterior part of the piriform cortex. Comparison with amygdala kindling and effects of antiepileptic drugs.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Diazepam; Electric Stimulation; Electrodes, Implanted; Female; Kindling, Neurologic; Phenobarbital; Rats; Rats, Inbred Strains; Valproic Acid | 1991 |
Serum lipids, lipoproteins and apolipoproteins A and B in epileptic patients treated with valproic acid, carbamazepine or phenobarbital.
Topics: Adolescent; Adult; Analysis of Variance; Apolipoproteins A; Apolipoproteins B; Carbamazepine; Child; Child, Preschool; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Epilepsy; Female; Humans; Lipids; Male; Middle Aged; Phenobarbital; Valproic Acid | 1991 |
Effect of phenobarbital on the pharmacokinetics of carbamazepine-10,11-epoxide, an active metabolite of carbamazepine.
Topics: Adult; Biological Availability; Carbamazepine; Drug Interactions; Epilepsy; Humans; Male; Middle Aged; Phenobarbital | 1991 |
Intraindividual variability of carbamazepine, phenobarbital, and phenytoin concentrations in saliva.
Topics: Adult; Carbamazepine; Fluorescence Polarization Immunoassay; Humans; Male; Phenobarbital; Phenytoin; Saliva | 1991 |
Comparison of enzyme immunoassay and fluorescence polarization immunoassay as techniques for measuring anticonvulsant drugs on the same analytical instrument.
Topics: Carbamazepine; Fluorescence Polarization Immunoassay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1991 |
Paroxysmal nocturnal dystonia presenting as excessive daytime somnolence.
Topics: Adult; Carbamazepine; Diagnosis, Differential; Dystonia; Electroencephalography; Evaluation Studies as Topic; Female; Humans; Imipramine; Male; Middle Aged; Phenobarbital; Sleep Stages; Sleep Wake Disorders; Trifluoperazine; Valproic Acid | 1990 |
[Clinical use of pharmacologic monitoring at a hospital community].
Topics: Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Utilization; Humans; Phenobarbital; Phenytoin; Product Surveillance, Postmarketing; Spain; Theophylline; Valproic Acid | 1990 |
Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy.
Topics: Administration, Oral; Adolescent; Adult; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
The inhibitory effect of anticonvulsants on human sperm motility: measured with a trans-membrane migration method.
Topics: Adult; Anticonvulsants; Carbamazepine; Cell Membrane; Depression, Chemical; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sperm Motility; Valproic Acid | 1990 |
Possible roles for frequent salivary antiepileptic drug monitoring in the management of epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Female; Humans; Male; Menstruation; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Saliva | 1990 |
Simultaneous determination of six antiepileptic drugs by capillary gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Hydroxides; Phenobarbital; Phenytoin; Potassium; Potassium Compounds; Primidone; Valproic Acid | 1990 |
Anticonvulsant-responsive panic attacks with temporal lobe EEG abnormalities.
Topics: Adolescent; Adult; Anticonvulsants; Brain Damage, Chronic; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Female; Humans; Male; Middle Aged; Neurocognitive Disorders; Neurologic Examination; Panic Disorder; Phenobarbital; Phenytoin | 1990 |
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 1990 |
[The use of phenobarbital and carbamazepine (finlepsin) in children with epilepsy and cerebral spastic palsy with epileptic syndrome].
Topics: Adolescent; Carbamazepine; Cerebral Palsy; Child; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Muscle Spasticity; Phenobarbital | 1990 |
Direct serum injection high-performance liquid chromatographic method for the simultaneous determination of phenobarbital, carbamazepine and phenytoin.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
A simple and disposable visual measuring device to assay antiepileptic drugs from whole blood samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
Comparison of human, bovine, and newborn calf serum in the preparation of external quality assurance samples for therapeutic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, Gas; Chromatography, High Pressure Liquid; Fluorescence Polarization; Humans; Immunoassay; Immunoenzyme Techniques; Nephelometry and Turbidimetry; Phenobarbital; Phenytoin; Quality Control; Radioimmunoassay; Theophylline | 1990 |
Rapid anti-epileptic drug assay.
Topics: Anticonvulsants; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Ethosuximide; Humans; Patient Compliance; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
Selective response to carbamazepine in a case of organic mood disorder.
Topics: Aged; Carbamazepine; Depressive Disorder; Female; Humans; Neurocognitive Disorders; Phenobarbital; Phenytoin; Valproic Acid | 1990 |
[Computerized analysis of EEG background activity in mono-therapeutic patients with epilepsy--relationships between antiepileptic drugs and types of seizures].
Topics: Adult; Anticonvulsants; Brain Mapping; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Image Processing, Computer-Assisted; Male; Middle Aged; Phenobarbital; Valproic Acid | 1990 |
Development of monoclonal antibodies for therapeutic drug monitoring.
Topics: Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Cross Reactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1990 |
Effects of age and antiepileptic drugs on plasma levels and kinetics of clobazam and N-desmethylclobazam.
Topics: Adolescent; Adult; Age Factors; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Child, Preschool; Clobazam; Drug Therapy, Combination; Epilepsy; Humans; Infant; Phenobarbital; Phenytoin; Time Factors; Valproic Acid | 1990 |
Postmortem serum protein binding and brain concentrations of antiepileptic drugs in autoptic specimens from 45 epileptic patients.
Topics: Anticonvulsants; Blood Proteins; Brain; Carbamazepine; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
Comparative experimental study of antiepileptics--regional specificity of antiepileptic action of carbamazepine, phenobarbital and valproate sodium.
Topics: Animals; Anticonvulsants; Carbamazepine; Epilepsy; Hippocampus; Male; Motor Cortex; Phenobarbital; Rabbits; Valproic Acid; Visual Cortex | 1990 |
The effect of interstimulation interval on the assessment of anticonvulsant drug potency in fully kindled rats.
Topics: Animals; Anticonvulsants; Ataxia; Carbamazepine; Kindling, Neurologic; Male; Phenobarbital; Rats; Rats, Inbred Strains; Seizures; Time Factors | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--carbamazepine.
Topics: Aging; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Valproic Acid | 1990 |
Analysis of the factors influencing anti-epileptic drug concentrations--valproic acid.
Topics: Adolescent; Adult; Aging; Aspartate Aminotransferases; Body Weight; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Regression Analysis; Retrospective Studies; Sex Factors; Valproic Acid | 1990 |
Temperature effects on the estimation of free levels of phenytoin carbamazepine and phenobarbitone.
Topics: Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Protein Binding; Temperature | 1990 |
Evaluation of the Ames Seralyzer for the determination of carbamazepine, phenobarbital, and phenytoin concentrations in saliva.
Topics: Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization Immunoassay; Humans; Phenobarbital; Phenytoin; Saliva | 1990 |
Phenobarbital hepatotoxicity in an 8-month-old infant.
Topics: Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Humans; Infant; Lymphocytes; Male; Methylprednisolone; Phenobarbital; Phenytoin | 1990 |
Effects of anticonvulsants on hippocampus-generating seizures.
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Dose-Response Relationship, Drug; Electric Stimulation; Female; Hippocampus; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Seizures | 1990 |
Phenobarbital treatment and major depressive disorder in children with epilepsy: a naturalistic follow-up.
Topics: Adolescent; Analysis of Variance; Carbamazepine; Child; Depressive Disorder; Epilepsy; Follow-Up Studies; Humans; Iatrogenic Disease; Pennsylvania; Phenobarbital; Psychopathology | 1990 |
Potentiation by glycine of anticonvulsant drugs in maximal electroshock seizures in rats.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, High Pressure Liquid; Diazepam; Drug Interactions; Drug Synergism; Electroshock; Glycine; Male; Nervous System Diseases; Phenobarbital; Rats; Rats, Inbred Strains; Seizures; Taurine | 1990 |
Influence of surgery and antiepileptic drugs on seizures symptomatic of cerebral tumours.
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Period | 1990 |
Serum protein binding of antiepileptic drugs in Sri Lankans.
Topics: Adolescent; Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Sri Lanka | 1990 |
Pharmacokinetics of anticonvulsants in pregnancy: alterations in plasma protein binding.
Topics: Adult; Anticonvulsants; Blood Proteins; Carbamazepine; Epilepsy; Female; Humans; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1990 |
Anticonvulsant drug mechanisms of action.
Topics: Action Potentials; Animals; Anticonvulsants; Barbiturates; Benzodiazepines; Carbamazepine; Clonazepam; Electroshock; gamma-Aminobutyric Acid; Humans; Ion Channels; Membrane Potentials; Mice; Neurons; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
The effect of repeated seizures on anticonvulsant drug response in the kindling model.
Topics: Animals; Brain; Carbamazepine; Kindling, Neurologic; Male; Membrane Potentials; Phenobarbital; Phenytoin; Rats; Seizures | 1987 |
Serum aspirin-esterase activity in epileptic patients receiving treatment with phenobarbital, phenytoin, carbamazepine and valproic acid.
Topics: Adult; Anticonvulsants; Aspirin; Carbamazepine; Epilepsy; Esterases; Female; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1989 |
The prevalence of adverse reactions to anticonvulsants in children with epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Valproic Acid | 1989 |
[Plasma determination of 7 common drugs by high performance liquid chromatography].
Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid | 1989 |
Carnitine deficiency associated with anticonvulsant therapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Carnitine; Cerebral Palsy; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1989 |
Variations in protein binding of drugs in plasma and serum.
Topics: Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Fluoroimmunoassay; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Protein Binding; Theophylline; Valproic Acid | 1989 |
Cost-effective assays for use in monitoring carbamazepine, phenobarbital, and phenytoin in serum.
Topics: Carbamazepine; Chromatography, Gas; Cost-Benefit Analysis; Fluoroimmunoassay; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Reference Standards | 1989 |
Effects of anticonvulsants on plasma levels and entero-hepatic circulation of valproic acid and on hepatic drug metabolizing enzyme activities in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Enterohepatic Circulation; Liver; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Inbred Strains; Valproic Acid | 1989 |
Sustained attention during the interictal period of mentally normal children with epilepsy or febrile convulsions, and the influence of anticonvulsants and seizures on attention.
Topics: Anticonvulsants; Attention; Carbamazepine; Child; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Female; Humans; Male; Neuropsychological Tests; Phenobarbital; Psychomotor Performance; Valproic Acid | 1989 |
Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slices.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Cell Membrane Permeability; Epilepsy; Hippocampus; In Vitro Techniques; Ion Channels; Midazolam; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1985 |
Simultaneous quantitation of salivary carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbitone by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Saliva; Spectrophotometry, Ultraviolet | 1989 |
Dosing accuracy of antiepileptic drug regimens as determined by serum concentrations in outpatient epilepsy clinic patients.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Outpatients; Phenobarbital; Phenytoin | 1989 |
Effects of carbamazepine and phenobarbital on kainic acid-induced model of psychomotor seizures during ontogenesis in the rat.
Topics: Aging; Animals; Carbamazepine; Dose-Response Relationship, Drug; Kainic Acid; Male; Phenobarbital; Rats; Rats, Inbred Strains; Seizures | 1989 |
Daily salivary anticonvulsant monitoring in patients with intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Saliva | 1989 |
EMIT measurement of carbamazepine, phenobarbital, and theophylline in the "Monarch" centrifugal analyzer.
Topics: Autoanalysis; Carbamazepine; Humans; Immunoenzyme Techniques; Phenobarbital; Quality Control; Theophylline | 1989 |
A micromethod for the estimation of free levels of anticonvulsant drugs in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Fluorescence Polarization; Fluorescent Antibody Technique; Humans; Microchemistry; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Ultrafiltration | 1989 |
Barbiturate-related connective tissue disorders.
Topics: Adult; Aged; Anticonvulsants; Barbiturates; Carbamazepine; Connective Tissue Diseases; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Prospective Studies | 1989 |
Saliva monitoring of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1989 |
Value of saliva anticonvulsant monitoring in pregnancy and the newborn.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Infant, Newborn; Monitoring, Physiologic; Phenobarbital; Phenytoin; Pregnancy; Primidone; Saliva | 1989 |
The effect of anticonvulsants on the dexamethasone suppression test.
Topics: Adult; Anticonvulsants; Bipolar Disorder; Carbamazepine; Depressive Disorder; Dexamethasone; Epilepsy; Humans; Hydrocortisone; Phenobarbital; Phenytoin | 1989 |
Effect of aminophylline upon the protective activity of common antiepileptic drugs and their plasma levels in mice.
Topics: Aminophylline; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Male; Mice; Phenobarbital; Phenytoin; Seizures | 1989 |
Effects of intranigral application of clinically-effective anticonvulsants on electroshock-induced seizures.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Electroshock; Hindlimb; Injections; Male; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Substantia Nigra | 1989 |
[Mechanism of action of antiepileptic drugs].
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; gamma-Aminobutyric Acid; Ion Exchange; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Synaptic Transmission; Valproic Acid | 1987 |
Automated determination of drugs in serum by liquid chromatography with column-switching. I. Separation of antiepileptic drugs and metabolites.
Topics: Acetonitriles; Anticonvulsants; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Perchlorates; Phenobarbital; Phenytoin; Quality Control; Regression Analysis; Statistics as Topic; Trichloroacetic Acid; Valproic Acid | 1988 |
Differential effects of anticonvulsants on developing neurons in vitro.
Topics: Animals; Anticonvulsants; Binding, Competitive; Carbamazepine; Cells, Cultured; Chick Embryo; Immunohistochemistry; Neurons; Phenobarbital; Phenytoin; Receptors, Cell Surface; Receptors, Nerve Growth Factor; Valproic Acid | 1988 |
Antiepileptic drugs and cerebral glucose metabolism.
Topics: Anticonvulsants; Brain; Carbamazepine; gamma-Aminobutyric Acid; Glucose; Humans; Phenobarbital; Phenytoin; Receptors, GABA-A; Tomography, Emission-Computed | 1988 |
Serum 5'-nucleotidase in patients receiving anti-epileptic drugs.
Topics: 5'-Nucleotidase; Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Male; Middle Aged; Nucleotidases; Phenobarbital; Phenytoin; Sex Factors | 1985 |
Comparison of fluorescence polarization immunoassay and high performance liquid chromatography for the quantitative determination of phenytoin, phenobarbitone and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Fluorescence Polarization; Humans; Immunoassay; Phenobarbital; Phenytoin; Quality Control | 1986 |
Rapid and sensitive determination of ethotoin as well as carbamazepine, phenobarbital, phenytoin and primidone in human serum.
Topics: Carbamazepine; Gas Chromatography-Mass Spectrometry; Humans; Hydantoins; Kinetics; Phenobarbital; Phenytoin; Powders; Primidone; Tablets | 1986 |
Evidence for involvement of the astrocytic benzodiazepine receptor in the mechanism of action of convulsant and anticonvulsant drugs.
Topics: Animals; Anticonvulsants; Astrocytes; Barbiturates; Benzodiazepinones; Brain; Carbamazepine; Cells, Cultured; Convulsants; Diazepam; Ethosuximide; Mice; Neurons; Pentylenetetrazole; Phenobarbital; Picrotoxin; Receptors, GABA-A; Sesterterpenes; Trimethadione; Valproic Acid | 1988 |
Anticonvulsant drugs effective against human temporal lobe epilepsy prevent seizures but not neurotoxicity induced in rats by quinolinic acid: electroencephalographic, behavioral and histological assessments.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Chlorpromazine; Diazepam; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Male; Phenobarbital; Phenytoin; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1986 |
Nursing interventions for anticonvulsant drug interactions.
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Drug Interactions; Humans; Nursing Care; Patient Education as Topic; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1986 |
Valproate-associated hyperammonemia and DL-carnitine supplement.
Topics: Adolescent; Adult; Ammonia; Carbamazepine; Carnitine; Child; Child, Preschool; Disabled Persons; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Valproic Acid | 1987 |
Potent depressant action of baclofen on hippocampal epileptiform activity in vitro: possible use in the treatment of epilepsy.
Topics: Animals; Anticonvulsants; Baclofen; Carbamazepine; Diazepam; Epilepsy; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Phenobarbital; Synaptic Transmission | 1986 |
[The correlation between concentrations of anticonvulsive drugs in the brain and various parameters of maximal electroshock seizures in mice].
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Drug Evaluation, Preclinical; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1986 |
Carbamazepine, phenytoin and phenobarbital in drug-resistant partial epilepsies.
Topics: Adolescent; Adult; Carbamazepine; Drug Evaluation; Drug Resistance; Epilepsies, Partial; Epilepsy, Temporal Lobe; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1986 |
Therapeutic drug monitoring in patients with chronic renal failure: evaluation of the Abbott TDx drug assay system.
Topics: Carbamazepine; Cross Reactions; Digoxin; Gentamicins; Humans; Immunoassay; Kidney Failure, Chronic; Lidocaine; Monitoring, Physiologic; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Valproic Acid; Vancomycin | 1986 |
The effect of phenobarbital and carbamazepine on the ethanol withdrawal reaction in the rat.
Topics: Alcoholic Intoxication; Animals; Carbamazepine; Ethanol; Humans; Male; Phenobarbital; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1986 |
Phenylethylmalonamide serum levels in patients treated with primidone and the effects of other antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Humans; Malonates; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Valproic Acid | 1986 |
A comparative study of the relative influence of different anticonvulsant drugs, UV exposure and diet on vitamin D and calcium metabolism in out-patients with epilepsy.
Topics: Adult; Calcium; Carbamazepine; Diet; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Ultraviolet Rays; Valproic Acid; Vitamin D | 1986 |
[Treatment of epileptic patients with Jacksonian seizures].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Temporal Lobe; Humans; Nitrazepam; Phenobarbital; Valproic Acid | 1986 |
Effects of anticonvulsant drugs on substantia nigra pars reticulata neurons.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Ethosuximide; Male; Neurons; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Substantia Nigra; Trimethadione; Valproic Acid | 1986 |
Synergistic effects of oxiracetam and piracetam in combination with antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Drug Synergism; Drug Therapy, Combination; Epilepsy; Male; Phenobarbital; Phenytoin; Piracetam; Pyrrolidines; Pyrrolidinones; Rats; Valproic Acid | 1986 |
Inhibition of quisqualate-induced seizures by glutamic acid diethyl ester and anti-epileptic drugs.
Topics: Aminooxyacetic Acid; Animals; Anticonvulsants; Carbamazepine; Diazepam; Female; Glutamates; Mice; Oxadiazoles; Phenobarbital; Phenytoin; Quisqualic Acid; Seizures; Valproic Acid | 1986 |
Changes in epileptic spike configuration associated with attainment of seizure control.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsies, Partial; Epilepsy, Temporal Lobe; Humans; Phenobarbital | 1986 |
[Modification of psychophysical performance of the human by anticonvulsants].
Topics: Anticonvulsants; Arousal; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Mental Processes; Phenobarbital; Psychological Tests; Psychomotor Performance; Valproic Acid | 1987 |
Anticonvulsant drugs in monotherapy. Effect on the fetus.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fetal Growth Retardation; France; Humans; Infant; Infant, Low Birth Weight; Infant, Newborn; Italy; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Sweden; Valproic Acid | 1987 |
[Cognitive effects of antiepileptic drugs].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cognition Disorders; Epilepsy; Humans; Memory Disorders; Phenobarbital; Phenytoin; Temporal Lobe; Valproic Acid | 1987 |
Anticonvulsant medication in a mental handicap hospital: 1972-1982.
Topics: Anticonvulsants; Carbamazepine; Female; Hospitals, Psychiatric; Humans; Intellectual Disability; Male; Phenobarbital; Phenytoin; Valproic Acid | 1987 |
Endocrine function changes in young males during long-term antiepileptic therapy with phenobarbitone and carbamazepine.
Topics: Adult; Carbamazepine; Drug Therapy, Combination; Endocrine Glands; Epilepsies, Partial; Epilepsy, Temporal Lobe; Hormones; Humans; Male; Phenobarbital | 1987 |
Thyroid function in children with long-term anticonvulsant treatment.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Infant; Male; Osmolar Concentration; Phenobarbital; Resins, Plant; Thyroid Gland; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Time Factors; Triiodothyronine; Valproic Acid | 1987 |
Antiepileptic drugs and puberty.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Estradiol; Female; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Phenobarbital; Puberty; Testosterone; Valproic Acid | 1988 |
Cytochrome P-450-catalyzed desaturation of valproic acid in vitro. Species differences, induction effects, and mechanistic studies.
Topics: Animals; Carbamazepine; Cytochrome P-450 Enzyme System; Deuterium; Enzyme Induction; Fatty Acids, Monounsaturated; Female; Gas Chromatography-Mass Spectrometry; Humans; Hydroxylation; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Valproic Acid | 1988 |
Anticonvulsant potency and neurotoxicity of valproate alone and in combination with carbamazepine or phenobarbital.
Topics: Animals; Brain; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Electroshock; Female; Mice; Mice, Inbred ICR; Neurotoxins; Pentylenetetrazole; Phenobarbital; Seizures; Valproic Acid | 1988 |
The role of ultrasound in the early diagnosis of fetal structural defects following maternal anticonvulsant therapy.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Diazepam; Female; Humans; Infant, Newborn; Maternal-Fetal Exchange; Middle Aged; Phenobarbital; Phenytoin; Pregnancy; Prenatal Diagnosis; Prospective Studies; Ultrasonography; Valproic Acid | 1988 |
Pharmacologic interactions between valproate and other drugs.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1988 |
Effects of long-lasting antiepileptic therapy on brainstem auditory evoked potentials.
Topics: Adolescent; Adult; Anticonvulsants; Brain Stem; Carbamazepine; Child; Epilepsies, Partial; Evoked Potentials, Auditory; Female; gamma-Aminobutyric Acid; Humans; Long-Term Care; Male; Middle Aged; Phenobarbital; Reaction Time; Valproic Acid | 1988 |
Anticonvulsant hypersensitivity syndrome. In vitro assessment of risk.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross Reactions; Drug Evaluation, Preclinical; Drug Hypersensitivity; Female; Humans; Inactivation, Metabolic; Infant; Lymphocytes; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Phenytoin; Risk | 1988 |
Free drug levels monitoring as a detector of false metabolic refractory epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital | 1988 |
Role of human serum biotinidase as biotin-binding protein.
Topics: Amidohydrolases; Binding Sites; Biotin; Biotinidase; Bromosuccinimide; Carbamazepine; Carrier Proteins; Centrifugation, Density Gradient; Chloromercuribenzoates; Chromatography, Gel; Globulins; Humans; Hydrogen-Ion Concentration; p-Chloromercuribenzoic Acid; Phenobarbital; Phenytoin; Serum Albumin | 1988 |
Shielded hydrophobic phase: a new concept for direct injection analysis of biological fluids by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Trimethoprim | 1988 |
[Serum levels of triiodothyronine, thyroxine and thyrotropin in children with epilepsy treated with amizepine, luminal and mizodine in a monotherapy system. Preliminary report].
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Male; Phenobarbital; Primidone; Thyrotropin; Thyroxine; Triiodothyronine | 1988 |
Effects of drugs on aminophylline elimination in rats.
Topics: Aminophylline; Animals; Behavior, Animal; Carbamazepine; Cimetidine; Drug Combinations; Drug Interactions; Erythromycin; Female; Half-Life; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Rifampin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination | 1988 |
Episodic nocturnal wanderings in non-epileptic young patients.
Topics: Adult; Brain; Carbamazepine; Electroencephalography; Female; Humans; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Somnambulism | 1988 |
Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography.
Topics: Adult; Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Male; Phenobarbital; Phenytoin; Quality Control; Statistics as Topic; Therapeutic Equivalency | 1988 |
[Influence of phenobarbital on pharmacokinetics of carbamazepine and its epoxide metabolite in the rabbit].
Topics: Animals; Carbamazepine; Male; Models, Biological; Phenobarbital; Rabbits | 1987 |
Simultaneous measurement of phenobarbital, carbamazepine, phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in serum by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Minor additive inducing effects of phenobarbital on carbamazepine clearance in patients on combined carbamazepine-phenytoin therapy.
Topics: Aged; Carbamazepine; Drug Interactions; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1987 |
Analysis of serum concentration of phenobarbital, phenytoin, carbamazepine and carbamazepine 10,11-epoxide by solvent-recycled liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Rapid measurement of anticonvulsant drug concentrations in the out-patient clinic, using HPLC with direct injection of plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin | 1987 |
Phenobarbital treatment and major depressive disorder in children with epilepsy.
Topics: Adolescent; Carbamazepine; Child; Depressive Disorder; Epilepsy; Humans; Phenobarbital; Suicide, Attempted | 1987 |
Measuring anti-convulsant levels in the accident and emergency department.
Topics: Adult; Carbamazepine; Emergencies; Epilepsy; Humans; Patient Compliance; Phenobarbital; Phenytoin; Prospective Studies | 1986 |
Anticonvulsant medications: an iatrogenic cause of tic disorders.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; Humans; Hyperkinesis; Male; Mephobarbital; Phenobarbital; Tic Disorders | 1986 |
[Phenomenon of "paradoxical poisoning" during antiepileptic therapy].
Topics: Adult; Anticonvulsants; Barbiturates; Carbamazepine; Child; Drug Synergism; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Phenobarbital; Phenytoin | 1986 |
Withdrawal of phenobarbital and carbamazepine in epileptic patients: a preliminary neuropsychological report.
Topics: Adolescent; Adult; Carbamazepine; Cognition Disorders; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Phenobarbital; Psychomotor Disorders; Substance Withdrawal Syndrome; Trail Making Test | 1986 |
Effect of influenza vaccine on serum anticonvulsant concentrations.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Influenza Vaccines; Influenza, Human; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Vaccination | 1986 |
[Anticonvulsants in the therapy of glioblastomas].
Topics: Adult; Anticonvulsants; Brain Neoplasms; Carbamazepine; Combined Modality Therapy; Drug Therapy, Combination; Female; Glioma; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis | 1986 |
Dexamethasone bioavailability: implications for DST research.
Topics: Biological Availability; Carbamazepine; Cushing Syndrome; Depressive Disorder; Dexamethasone; Humans; Phenobarbital; Phenytoin; Psychotic Disorders | 1987 |
Effect of chronic anticonvulsant monotherapy on lymphocyte subpopulations in adult epileptic patients.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Complement System Proteins; Epilepsy; Female; Humans; Immunoglobulins; Leukocyte Count; Lymphocytes; Male; Middle Aged; Phenobarbital; Phenytoin; T-Lymphocytes | 1985 |
Evaluation of an automated system (Optimate) for substrate-labeled fluorescent immunoassays.
Topics: Anti-Bacterial Agents; Carbamazepine; Evaluation Studies as Topic; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Indicators and Reagents; Methods; Phenobarbital; Phenytoin; Primidone; Quinidine; Theophylline | 1985 |
[Determination of antiepileptic serum levels in patients with mono- and polytherapy in correlation with the clinical picture of the disease].
Topics: Adolescent; Adult; Alkaline Phosphatase; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital | 1985 |
Effects of pregnancy on seizure threshold and the disposition and efficacy of antiepileptic drugs in the mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Electroshock; Female; Kinetics; Mice; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Seizures; Time Factors; Valproic Acid | 1985 |
Postictal pulmonary edema in children.
Topics: Carbamazepine; Child; Epilepsies, Partial; Furosemide; Humans; Intubation, Intratracheal; Male; Oxygen; Patient Compliance; Phenobarbital; Phenytoin; Positive-Pressure Respiration; Pulmonary Edema; Respiration, Artificial | 1985 |
Antiepileptic drug evaluation in a new animal model: spontaneous petit mal epilepsy in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Evaluation, Preclinical; Electroencephalography; Epilepsy, Absence; Ethosuximide; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Trimethadione; Valproic Acid | 1985 |
Effects of pregnancy on antiepileptic drug utilization.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Epilepsy; Female; Humans; Kinetics; Metabolic Clearance Rate; Patient Compliance; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Valproic Acid | 1985 |
Absence status appearing on eye-closure.
Topics: Adolescent; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Carbamazepine; Child; Clobazam; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Eyelids; Female; Humans; Phenobarbital; Sleep | 1985 |
Anticonvulsant drugs and the genetically epilepsy-prone rat.
Topics: Acoustic Stimulation; Amitriptyline; Animals; Anticonvulsants; Carbamazepine; Desipramine; Disease Models, Animal; Epilepsy; Ethosuximide; Imipramine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Seizures; Valproic Acid | 1985 |
Concurrent determination of valproic acid with other antiepileptic drugs by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Monotherapy and polytherapy for intractable epilepsies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1985 |
Interictal EEG prediction of response to antiepileptic drug monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prognosis; Sleep Deprivation; Valproic Acid | 1985 |
American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.
Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Child; Child Behavior Disorders; Clonazepam; Cognition; Humans; Infant; Memory Disorders; Phenobarbital; Phenytoin; Psychological Tests; Valproic Acid | 1985 |
Chronic valproic acid therapy and incidence of increases in venous plasma ammonia.
Topics: Adolescent; Adult; Aged; Ammonia; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
The optimum use of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Where, why, and what type of therapy.
Topics: Carbamazepine; Child; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Recurrence; Risk; Succinimides; Valproic Acid | 1985 |
Monitoring: the most important role of the pediatrician.
Topics: Activities of Daily Living; Anticonvulsants; Carbamazepine; Child, Preschool; Environmental Monitoring; Epilepsy; Ethosuximide; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Referral and Consultation; Social Support; Valproic Acid | 1985 |
Serum concentrations of valproic acid: influence of dose and comedication.
Topics: Adolescent; Adult; Body Weight; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid | 1985 |
Seizure control following administration of anticonvulsant drugs in the quaking mouse.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Mice; Mice, Inbred C57BL; Mice, Quaking; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1985 |
Use of total and free anticonvulsant serum levels in clinical practice.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Valproic Acid | 1985 |
Alternative single anticonvulsant drug therapy for refractory epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1986 |
The influence of seizure type on the efficacy of plasma concentrations of phenytoin, phenobarbital, and carbamazepine.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1986 |
Carbamazepine in febrile seizures.
Topics: Carbamazepine; Humans; Infant; Phenobarbital; Seizures, Febrile | 1985 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
Interpreting drug levels.
Topics: Carbamazepine; Digoxin; Phenobarbital; Phenytoin; Theophylline | 1985 |
Epilepsy in a community--management and social impact.
Topics: Adolescent; Adult; Aged; Ambulatory Care Facilities; Carbamazepine; Craniocerebral Trauma; Epilepsy; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Seizures; Socioeconomic Factors; Stress, Physiological | 1985 |
Effect of antiepileptic drugs on short-latency somatosensory evoked potentials.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Evoked Potentials, Somatosensory; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Reaction Time | 1985 |
Use of serum drug concentrations in outpatient clinics.
Topics: Carbamazepine; Digoxin; Humans; Medication Systems, Hospital; Outpatient Clinics, Hospital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Procainamide; Quinidine; Theophylline; Wisconsin | 1985 |
Lateral gaze nystagmus in carbamazepine-treated epileptic patients: correlation with total and free plasma concentrations of parent drug and its 10,11-epoxide metabolite.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Nystagmus, Pathologic; Phenobarbital | 1985 |
Serum low-density lipoprotein and high-density lipoprotein cholesterol, and liver size in subjects on drugs inducing hepatic microsomal enzymes.
Topics: Adult; Carbamazepine; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Humans; Liver; Male; Microsomes, Liver; Middle Aged; Organ Size; Phenobarbital; Phenytoin; Risk | 1985 |
The role of antiepileptics in sudden death in epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Death, Sudden; Epilepsy; Female; Humans; Male; Patient Compliance; Phenobarbital; Phenytoin | 1985 |
Coarse features in epilepsy as a consequence of anticonvulsant therapy. Report of cases in two pairs of identical twins.
Topics: Acromegaly; Adult; Anticonvulsants; Carbamazepine; Child; Diazepam; Diseases in Twins; Epilepsy; Epilepsy, Tonic-Clonic; Ethosuximide; Face; Female; Haloperidol; Humans; Hydantoins; Male; Phenobarbital; Phenytoin; Primidone; Thiazines | 1973 |
Letter: Treatment of hiccup.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Drug Therapy, Combination; Female; Hiccup; Humans; Male; Phenobarbital; Phenytoin | 1974 |
The effect of certain drugs on the plasma protein binding of phenytoin.
Topics: Anticonvulsants; Aspirin; Binding Sites; Blood Proteins; Carbamazepine; Dialysis; Diazepam; Ethosuximide; Humans; In Vitro Techniques; Phenobarbital; Phenytoin; Protein Binding; Serum Albumin; Temperature; Thiazines; Ultrafiltration | 1973 |
Effect of clonazepam (Ro 5-4023) on epileptic seizures.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepinones; Carbamazepine; Chlorobenzenes; Drug Evaluation; Drug Therapy, Combination; Epilepsy; Fatigue; Female; Humans; Hydantoins; Male; Nitro Compounds; Phenobarbital; Primidone; Thiazines; Time Factors | 1973 |
Interference in the Zimmerman test for steroids.
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; 17-Ketosteroids; Carbamazepine; Evaluation Studies as Topic; Humans; Methods; Nitrazepam; Phenobarbital; Phenytoin; Spectrometry, Fluorescence; Spectrophotometry; Thiazines | 1974 |
Choreo-athetosis and encephalopathy induced by phenytoin.
Topics: Adolescent; Adult; Ataxia; Athetosis; Carbamazepine; Chorea; Diplopia; Electroencephalography; Epilepsy; Humans; Intelligence; Male; Nystagmus, Pathologic; Phenobarbital; Phenytoin; Primidone; Thiazines | 1974 |
Epilepsy.
Topics: Adrenocorticotropic Hormone; Carbamazepine; Diazepam; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant, Newborn; Liver; Nitrazepam; Phenobarbital; Phenytoin; Prednisolone; Primidone; Spasm; Syndrome; Thiazines | 1974 |
Psychomotor epilepsy in childhood.
Topics: Bromides; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Infant; Phenobarbital; Phenytoin; Primidone; Radiography; Recurrence; Skull; Time Factors | 1974 |
Paroxysmal kinesignenic choreoathetosis. Report of a case relieved by carbamazepine.
Topics: Adolescent; Athetosis; Carbamazepine; Diazepam; Dibenzazepines; Diphenhydramine; Female; Humans; Huntington Disease; Lactose; Phenobarbital; Phenytoin | 1969 |
Radiologic bone changes and hypocalcemia with anticonvulsant therapy in epilepsy.
Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Anticonvulsants; Back Pain; Calcium; Carbamazepine; Diarrhea; Epilepsy; Female; Femur; Fractures, Bone; Humans; Hypocalcemia; Male; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Radiography | 1972 |
[Severe rachitic osteopathy during long-term anticonvulsant treatment].
Topics: Administration, Oral; Alkaline Phosphatase; Anticonvulsants; Biopsy; Calcium; Carbamazepine; Child; Cholecalciferol; Epilepsy, Tonic-Clonic; Humans; Ilium; Iron; Long-Term Care; Male; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone; Rickets | 1973 |
Peripheral nerve function in long-term therapy with diphenylhydantoin. A clinical and electrophysiologic correlation.
Topics: Adult; Aged; Carbamazepine; Electric Stimulation; Electromyography; Epilepsy; Ethosuximide; Evoked Potentials; Female; Folic Acid; Humans; Male; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Peroneal Nerve; Phenobarbital; Phenytoin; Primidone; Reaction Time; Reflex, Monosynaptic; Sural Nerve; Time Factors; Vitamin B 12 | 1974 |
Drug treatment of epilepsy in childhood.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Infant; Paraldehyde; Phenobarbital; Phenytoin; Primidone; Thiazines | 1969 |
A comprehensive scheme for the evaluation of anticonvulsant concentrations in blood using thin-layer chromatography.
Topics: Acetazolamide; Anticonvulsants; Benzazepines; Carbamazepine; Chlordiazepoxide; Chromatography, Thin Layer; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Mephobarbital; Nitro Compounds; Oxazepam; Phenobarbital; Phenytoin; Primidone; Succinimides; Thiazines | 1971 |
[Medical treatment of epilepsy].
Topics: Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Humans; Hydantoins; Phenobarbital; Phenytoin; Thiazines | 1971 |
Anticonvulsant drugs. I. Patho-physiological and pharmacological aspects.
Topics: Acetates; Acetazolamide; Anticonvulsants; Carbamazepine; Diazepam; Dibenzazepines; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Succinimides; Thiazines; Trimethadione | 1972 |
Simultaneous determination of some antiepileptic drugs by gas-liquid chromatography.
Topics: Analysis of Variance; Carbamazepine; Chromatography, Gas; Colorimetry; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1974 |
Broad-spectrum simultaneous GLC assay of nonderivatized antiepileptic drugs.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Quality Control; Trimethadione | 1974 |
[Phenomenology and therapy of temporal epilepsy in various age groups].
Topics: Adolescent; Adult; Carbamazepine; Child; Epilepsy, Temporal Lobe; Humans; Phenobarbital | 1974 |
The action of some anticonvulsant drugs on cobalt-induced epilepsy and on the bemegride threshold in alert cats.
Topics: Animals; Anticonvulsants; Bemegride; Carbamazepine; Cats; Cobalt; Diazepam; Electroencephalography; Epilepsies, Partial; Epilepsy; Phenobarbital; Phenytoin | 1972 |
Simultaneous determination of carbamazapine ("Tegretol") and other anticonvulsants in human plasma by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Computers; Dibenzazepines; Humans; Hydantoins; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Quaternary Ammonium Compounds | 1973 |
Anticonvulsant drugs and spike propagation of motor nerves and skeletal muscle.
Topics: Action Potentials; Adult; Anticonvulsants; Body Temperature; Bromine; Carbamazepine; Cell Membrane Permeability; Diazepam; Electric Stimulation; Evoked Potentials; Humans; Motor Neurons; Muscles; Myofibrils; Neural Conduction; Phenobarbital; Skin Temperature; Ulnar Nerve | 1973 |
Preliminary observations of serum carbamazepine concentration in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1973 |
A rapid method for the estimation of anti-epileptic drugs in blood serum by gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Epilepsy; Ethosuximide; Evaluation Studies as Topic; Humans; Mephobarbital; Methods; Methylation; Microchemistry; Phenobarbital; Phenytoin; Primidone; Succinimides; Temperature; Time Factors; Trimethadione | 1973 |
The teratological effects of anticonvulsants and the effects on pregnancy and birth.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cleft Lip; Cleft Palate; Cyclohexanes; Epilepsy; Ethosuximide; Female; Humans; Hydantoins; Male; Mutation; Obstetric Labor Complications; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Propylamines | 1973 |
Influence of phenobarbital and diphenylhydantoin on plasma carbamazepine levels in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Depression, Chemical; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Pain; Phenobarbital; Phenytoin; Trigeminal Neuralgia | 1973 |
[Letter: Teratogenic hazards in antiepileptic therapy].
Topics: Abnormalities, Drug-Induced; Carbamazepine; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1974 |
Interaction between doxycycline and barbiturates.
Topics: Adult; Aged; Amobarbital; Barbiturates; Carbamazepine; Doxycycline; Drug Interactions; Enzyme Induction; Female; Half-Life; Humans; Male; Middle Aged; Pentobarbital; Phenobarbital; Phenytoin | 1974 |
[Pharmacological analysis of a case of postanoxic intention and action myoclonus].
Topics: 5-Hydroxytryptophan; Alcohols; Anticonvulsants; Benzoates; Carbamazepine; Chlorpromazine; Diazepam; Dibenzazepines; Dopamine; Ergotamine; Female; Haloperidol; Humans; Hypoxia, Brain; Methotrimeprazine; Methyldopa; Methysergide; Middle Aged; Myoclonus; Norepinephrine; Phenobarbital; Pyrrolidines; Stereotaxic Techniques; Sulfonamides; Tranquilizing Agents; Trihexyphenidyl | 1971 |
An isothermal GLC determination of the plasma levels of carbamazepine, diphenylhydantoin, phenobarbitone and primidone.
Topics: Benzyl Compounds; Carbamazepine; Chloroform; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Phthalic Acids; Primidone; Solubility; Spectrophotometry; Ultraviolet Rays | 1972 |
Antiepileptic drug concentrations in plasma. Clinical evaluation of 321 estimations in 237 unselected patients.
Topics: Carbamazepine; Chromatography, Gas; Chromatography, Thin Layer; Epilepsy; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
Rapid routine determination of some anti-epileptic drugs in serum by gas chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin | 1972 |
GLC determination of carbamazepine in plasma.
Topics: Benzocycloheptenes; Carbamates; Carbamazepine; Chromatography, Gas; Humans; Methods; Phenobarbital; Phenytoin; Primidone | 1972 |
[Speech disorders in children with cerebral convulsions].
Topics: Adolescent; Barbiturates; Carbamazepine; Drug Hypersensitivity; Electroencephalography; Epilepsy; Ethosuximide; Humans; Male; Phenobarbital; Phenytoin; Primidone; Speech Disorders; Speech Therapy; Verbal Behavior | 1972 |
Bone density in patients receiving long-term anticonvulsant therapy.
Topics: Absorptiometry, Photon; Adult; Alkaline Phosphatase; Anticonvulsants; Calcium; Carbamazepine; Epilepsy; Female; Forearm; Heel; Humans; Iodine Radioisotopes; Middle Aged; Osteomalacia; Phenobarbital; Phenytoin; Phosphorus; Primidone | 1971 |
[Our experiences with Tegretol in the treatment of epilepsy].
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Drug Synergism; Epilepsy; Female; Headache; Humans; Male; Middle Aged; Phenobarbital; Vertigo; Vomiting | 1971 |
[Anticonvulsants. 1. Chemical survey].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chemical Phenomena; Chemistry; Diazepam; Hydantoins; Phenobarbital; Primidone; Pyrrolidines; Trimethadione | 1971 |
Anticonvulsant drugs and folic acid in young mentally retarded epileptic patients. A study of serum folate, fit frequency and I.Q.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Folic Acid; Humans; Intellectual Disability; Intelligence Tests; Male; Phenobarbital; Phenytoin; Primidone; Prognosis | 1971 |
A case of periodic somnolence whose sleep was induced by glucose.
Topics: Adolescent; Adult; Carbamazepine; Depression; Electroencephalography; Food Preferences; Glucose; Humans; Hunger; Imipramine; Male; Mental Disorders; Paresthesia; Pedigree; Periodicity; Phenobarbital; Potassium; Psychological Tests; Sleep Wake Disorders | 1969 |
Gas chromatographic assay of underivatized 5,5-diphenylhydantoin (dilantin) in plasma extracts.
Topics: Carbamazepine; Chloroform; Chromatography, Gas; Coma; Epilepsy; Humans; Hydrogen-Ion Concentration; Methods; Phenobarbital; Phenytoin; Primidone | 1971 |
[Correlation between the prescribed dose of anti-epileptic agents and the blood levels measured].
Topics: Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1971 |
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Anticonvulsant therapy and its possible consequences on peripheral nervous system: a neurographic study.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Neural Conduction; Peripheral Nerves; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin | 1984 |
Phenytoin interacts with calcium channels in brain membranes.
Topics: Animals; Brain; Calcium; Carbamazepine; Clonazepam; In Vitro Techniques; Ion Channels; Male; Nifedipine; Nitrendipine; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1984 |
Psychiatric implications of anticonvulsant drugs.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Humans; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
[Effects of drug interaction in infancy (author's transl)].
Topics: Carbamazepine; Child; Chloramphenicol; Clonazepam; Dexamethasone; Drug Interactions; Humans; Isoniazid; Metronidazole; Phenobarbital; Phenytoin; Sulfonamides; Valproic Acid | 1980 |
[Effect of barbexaclone treatment on thyroid function in epileptic children and juveniles (author's transl)].
Topics: Adolescent; Carbamazepine; Child; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Propylamines; Succinimides; Thyroid Hormones | 1980 |
Choice of anticonvulsants in epilepsy.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Epilepsy; Ethosuximide; Follow-Up Studies; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1981 |
The influence of antiepileptic drugs on the electroencephalogram: a review of controlled clinical studies.
Topics: Anti-Anxiety Agents; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
[Rise in gamma-GT during anticonvulsive therapy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Liver; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Pharmacokinetics of antiepileptic drugs.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Ethosuximide; Female; Half-Life; Humans; Infant; Infant, Newborn; Intestinal Absorption; Kinetics; Male; Metabolic Clearance Rate; Phenobarbital; Phenytoin; Pregnancy; Primidone; Protein Binding; Valproic Acid | 1983 |
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy.
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12 | 1983 |
A rapid gas liquid chromatography method for simultaneous determination of various anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Plasma concentrations of valproate during maintenance therapy in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Female; Half-Life; Humans; Male; Phenobarbital; Phenytoin; Valproic Acid | 1982 |
Interactions between primidone, carbamazepine, and nicotinamide.
Topics: Animals; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Infant; Male; Mice; Mice, Inbred Strains; Niacinamide; Phenobarbital; Phenylethylmalonamide; Primidone | 1982 |
Differential effects of the anticonvulsants phenobarbital, ethosuximide and carbamazepine on neuromuscular transmission.
Topics: Acetylcholine; Animals; Carbamazepine; Ethosuximide; Membrane Potentials; Neuromuscular Junction; Phenobarbital; Rana pipiens; Synaptic Transmission | 1980 |
Role of inhibitory mechanisms in trigeminal neuralgia.
Topics: Animals; Baclofen; Carbamazepine; Cats; Electric Stimulation; Maxillary Nerve; Neural Inhibition; Phenobarbital; Phenytoin; Synaptic Transmission; Trigeminal Neuralgia; Trigeminal Nuclei | 1981 |
Anticonvulsant peripheral neuropathy: a clinical and electrophysiological study of patients on single drug treatment with phenytoin, carbamazepine or barbiturates.
Topics: Adolescent; Adult; Aged; Barbiturates; Carbamazepine; Evoked Potentials, Somatosensory; Humans; Median Nerve; Middle Aged; Neural Conduction; Peripheral Nervous System Diseases; Phenobarbital; Phenytoin; Primidone; Sural Nerve | 1982 |
Logit-log calibration curves for EMIT assays.
Topics: Anticonvulsants; Carbamazepine; Ethosuximide; Glucose-6-Phosphate; Glucosephosphates; Humans; Immunoenzyme Techniques; Kinetics; Mathematics; NAD; Phenobarbital; Phenytoin; Primidone; Spectrophotometry | 1983 |
Semi-automated continuous-flow enzyme immunoassay for antiepileptic drugs in serum.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Reagent Kits, Diagnostic | 1983 |
Adaptation of microvolume EMIT assays for theophylline, phenobarbital, phenytoin, carbamazepine, primidone, ethosuximide, and gentamicin to a CentrifiChem chemistry analyzer.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Centrifugation; Ethosuximide; Gentamicins; Humans; Immunoenzyme Techniques; Microchemistry; Phenobarbital; Phenytoin; Primidone; Theophylline | 1983 |
Usefulness of enzyme multiplied immunoassay technique (EMIT) in the study of intoxications caused by anticonvulsive drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diazepam; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1983 |
Simultaneous measurement of ethosuximide, primidone, phenobarbital, phenytoin, carbamazepine, and their bioactive metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone | 1984 |
Performance of a new automated substrate-labeled fluorescence immunoassay system evaluated by comparative therapeutic monitoring of five drugs.
Topics: Autoanalysis; Carbamazepine; Chromatography, Gas; Chromatography, High Pressure Liquid; Drug Stability; Fluorescent Antibody Technique; Humans; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Quinidine; Spectrometry, Fluorescence; Theophylline | 1984 |
A monkey model for status epilepticus: carbamazepine and valproate compared to three standard anticonvulsants.
Topics: Aluminum Hydroxide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Macaca mulatta; Male; Phenobarbital; Phenytoin; Pyridoxine; Status Epilepticus; Valproic Acid | 1983 |
The effect of chronic anticonvulsant therapy on serum lipids and lipoproteins in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cholesterol; Epilepsy; Humans; Lipoproteins, HDL; Phenobarbital; Stimulation, Chemical; Valproic Acid | 1983 |
Reduction of two-drug therapy in intractable epilepsy.
Topics: Adult; Anticonvulsants; Carbamazepine; Clonazepam; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Prospective Studies; Valproic Acid | 1983 |
Therapeutic monitoring of serum antiepileptic drug levels.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Ethosuximide; Humans; Laboratories; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Time Factors; Valproic Acid | 1983 |
Serum folate concentrations during pregnancy in women with epilepsy: relation to antiepileptic drug concentrations, number of seizures, and fetal outcome.
Topics: Carbamazepine; Congenital Abnormalities; Epilepsy; Female; Fetal Death; Folic Acid; Humans; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications | 1983 |
Drugs for epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Humans; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid | 1983 |
Treatment of the nonconvulsive epilepsies.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1983 |
Antiepileptic drug therapy. Fine tuning the dosage regimen.
Topics: Anticonvulsants; Carbamazepine; Drug Administration Schedule; Drug Interactions; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Valproic Acid | 1983 |
[Pharmacotherapy of epilepsy--current problems and controversies].
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Absence; Epilepsy, Post-Traumatic; Epilepsy, Tonic-Clonic; Ethosuximide; Female; Humans; Infant; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Primidone; Seizures, Febrile; Status Epilepticus; Valproic Acid | 1983 |
The influence of anticonvulsants on fasting plasma ammonia and amino acid levels.
Topics: Amino Acids; Ammonia; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Glutamine; Glycine; Humans; Infant; Ornithine; Phenobarbital; Valproic Acid | 1983 |
Unnecessary polypharmacy in patients with frequent seizures.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Clonazepam; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Anticonvulsant potency of common antiepileptic drugs in the gerbil.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Ethosuximide; Female; Gerbillinae; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1983 |
The place of saliva in antiepileptic drug monitoring.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Female; Humans; Middle Aged; Phenobarbital; Plasma; Primidone; Saliva; Valproic Acid | 1984 |
Effects of some anticonvulsant drugs on brain GABA level and GAD and GABA-T activities.
Topics: 4-Aminobutyrate Transaminase; Animals; Anticonvulsants; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Oxidoreductases; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
The effects of various antiepileptic drugs on E-shock-induced amnesia in mice: dissociability of effects on convulsions and effects on memory.
Topics: Amnesia; Animals; Anticonvulsants; Carbamazepine; Clonazepam; Electroshock; Ethosuximide; Humans; Male; Mice; Phenobarbital; Phenytoin; Valproic Acid | 1984 |
Potentiation of the anticonvulsant effects of antiepileptic drugs by "nootropics"; a potential new therapeutic approach.
Topics: Animals; Anticonvulsants; Carbamazepine; Clonazepam; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Epilepsy; Humans; Memory Disorders; Phenobarbital; Piracetam; Pyrrolidinones; Rats; Valproic Acid; Vinca Alkaloids; Vincamine | 1984 |
Summing up of the success so far gained through choice of drugs or combinations of drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Cognition Disorders; Drug Therapy, Combination; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Psychotropic Drugs; Valproic Acid | 1984 |
[The incidence of postoperative epilepsy and prophylactic anticonvulsants in patients with intracranial aneurysm].
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intracranial Aneurysm; Male; Middle Aged; Phenobarbital; Phenytoin; Postoperative Complications; Valproic Acid | 1984 |
[Clinical and electroencephalographic features of the action of the psychic stimulant sydnocarb in various forms of epilepsy].
Topics: Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Humans; Oxadiazoles; Phenobarbital; Sydnones | 1984 |
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Topics: Anticonvulsants; Antipyrine; Carbamazepine; Enzyme Induction; Epilepsy; Female; Glucaric Acid; Half-Life; Humans; Immunoenzyme Techniques; Male; Microsomes, Liver; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Pharmacologic therapy of seizures in the elderly.
Topics: Aged; Anticonvulsants; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone; Seizures; Status Epilepticus; Valproic Acid | 1984 |
[Plasma levels of antiepileptic agents in the treatment of epilepsy].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Anticonvulsant drugs alter plasma tryptophan concentrations in epileptic patients: implications for antiepileptic action and mental function.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsies, Myoclonic; Epilepsies, Partial; Female; Humans; Kinetics; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Tryptophan | 1984 |
One drug for childhood grand mal: medical audit for three-year remissions.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Epilepsy, Tonic-Clonic; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1984 |
Epilepsy in children.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Diagnosis, Differential; Electroencephalography; Epilepsies, Partial; Epilepsy; Ethosuximide; Humans; Infant; Medical History Taking; Narcolepsy; Phenobarbital; Phenytoin; Physical Examination; Sleep Wake Disorders | 1984 |
The effect of computer generated comments on the distribution of anticonvulsant concentrations.
Topics: Anticonvulsants; Carbamazepine; Chemistry, Clinical; Computers; Humans; Phenobarbital; Phenytoin | 1984 |
Carbamazepine decreases catecholamine turnover in the rat brain.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Carbamazepine; Catecholamines; Dopamine; Dopamine beta-Hydroxylase; Female; Methoxyhydroxyphenylglycol; Methyltyrosines; Myocardium; Norepinephrine; Phenobarbital; Phenytoin; Probenecid; Rats; Rats, Inbred Strains | 1984 |
[Simultaneous determination of 4 anticonvulsant drugs by high pressure liquid chromatography (HPLC)].
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Excretion of organic acids associated with biotin deficiency in chronic anticonvulsant therapy.
Topics: Adult; Anticonvulsants; Biotin; Carbamazepine; Carboxy-Lyases; Carboxylic Acids; Epilepsy; Female; Humans; Male; Methylmalonyl-CoA Decarboxylase; Phenobarbital; Phenytoin; Primidone | 1984 |
Statistical analysis of performance of a liquid chromatographic assay of anticonvulsants involving solvent-demixing extraction and reciprocal internal standardization.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1984 |
Prognosis of chronic epilepsy with complex partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Epilepsy, Temporal Lobe; Evoked Potentials; Humans; Phenobarbital; Phenytoin; Primidone; Prognosis | 1984 |
The simultaneous determination of five anti-epileptic drugs in plasma by high performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1984 |
Therapeutic plasma levels of phenytoin, phenobarbital, and carbamazepine: individual variation in relation to seizure frequency and type.
Topics: Adolescent; Adult; Aged; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1984 |
Effects of phenobarbital, diphenylhydantoin and carbamazepine on thyroid function in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Child, Preschool; Epilepsy; Humans; Phenobarbital; Phenytoin; Thyroid Gland | 1984 |
External quality assessment of serum drug determinations in the Nordic countries.
Topics: Anticonvulsants; Carbamazepine; Data Collection; Humans; Phenobarbital; Phenytoin; Quality Control; Reference Standards | 1984 |
Evaluation of the Abbott TDx for the stat measurement of phenobarbital, phenytoin, carbamazepine, and theophylline.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Evaluation Studies as Topic; Fluorescence Polarization; Humans; Immunoassay; Microcomputers; Phenobarbital; Phenytoin; Theophylline | 1983 |
A quantitative determination of anticonvulsant-induced bone demineralization by an improved X-ray densitometry technique.
Topics: Absorptiometry, Photon; Adolescent; Adult; Aged; Anticonvulsants; Bone and Bones; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Microcomputers; Middle Aged; Minerals; Osteomalacia; Phenobarbital; Phenytoin; Time Factors | 1983 |
Reduction of polypharmacy for epilepsy in an institution for the retarded.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Intellectual Disability; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1983 |
Carbamazepine--erythromycin interaction leading to carbamazepine toxicity in four epileptic children.
Topics: Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Erythromycin; Female; Humans; Infant; Male; Phenobarbital | 1983 |
[Vomiting: symptom of an epileptic seizure].
Topics: Adult; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Female; Humans; Male; Phenobarbital; Vomiting | 1983 |
[Alpha 1-acid glycoprotein and carbamazepine].
Topics: Adult; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Orosomucoid; Phenobarbital | 1983 |
A design for the prospective evaluation of the efficacy and toxicity of antiepileptic drugs in adults.
Topics: Adult; Aged; Anticonvulsants; Behavior; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Random Allocation; Seizures | 1983 |
Carbamazepine in prophylaxis of febrile seizures in phenobarbital failures.
Topics: Carbamazepine; Child, Preschool; Fever; Humans; Infant; Phenobarbital; Seizures | 1983 |
Antiepileptic agents--primidone, phenobarbital, phenytoin, and carbamazepine by reversed-phase liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Primidone; Statistics as Topic | 1984 |
Effect of use of gel-barrier sampling tubes on determination of some antiepileptic drugs in serum.
Topics: Anticonvulsants; Blood Specimen Collection; Carbamazepine; Centrifugation; Chromatography, Liquid; Humans; Phenobarbital; Phenytoin; Time Factors | 1984 |
Together, phenobarbital and carbamazepine lower the alpha 1-acid glycoprotein concentration in plasma of epileptic patients.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Orosomucoid; Phenobarbital | 1984 |
[Anticonvulsive combined therapy (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1980 |
Organic convergence spasm.
Topics: Adolescent; Alpha Rhythm; Brain; Carbamazepine; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Tonic-Clonic; Eye Movements; Female; Humans; Neurologic Examination; Phenobarbital; Phenytoin; Spasm; Theta Rhythm | 1980 |
[Differential treatment of epilepsy patients].
Topics: Anticonvulsants; Carbamazepine; Diagnosis, Differential; Drug Therapy, Combination; Epilepsy; Epilepsy, Absence; Ethosuximide; Humans; Nitrazepam; Phenobarbital; Phenytoin | 1980 |
Pharmacokinetics of anticonvulsant drugs.
Topics: Anticonvulsants; Binding, Competitive; Brain; Carbamazepine; Drug Interactions; Drug Tolerance; Epilepsy; Folic Acid; Humans; Kinetics; Phenobarbital; Phenytoin; Protein Binding; Tissue Distribution; Valproic Acid | 1980 |
Adult-onset stuttering treated with anticonvulsants.
Topics: Adult; Brain Injuries; Carbamazepine; Drug Therapy, Combination; Epilepsy, Post-Traumatic; Female; Humans; Phenobarbital; Phenytoin; Stuttering | 1981 |
Monotherapy or polytherapy for epilepsy?
Topics: Adolescent; Adult; Carbamazepine; Clonazepam; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Epilepsy, Absence; Epilepsy, Tonic-Clonic; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1981 |
Drug treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Primidone; Seizures; Substance Withdrawal Syndrome; Valproic Acid | 1981 |
Valproic acid fails to displace phenobarbitone and carbamazepine from plasma protein binding sites in epileptic patients.
Topics: Adolescent; Adult; Binding, Competitive; Blood Proteins; Carbamazepine; Epilepsy; Female; Humans; Male; Phenobarbital; Protein Binding; Valproic Acid | 1981 |
Effects of some antiepileptic drugs in pentetrazol-induced convulsions in mice lesioned with kainic acid.
Topics: Acetazolamide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Dose-Response Relationship, Drug; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Pentylenetetrazole; Phenobarbital; Pyrrolidines; Seizures; Succinimides; Trimethadione; Valproic Acid | 1981 |
Recent advances in the treatment of epilepsy.
Topics: Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Phenytoin; Pregnancy; Valproic Acid | 1980 |
[A case of Pringle-Bourneville disease].
Topics: Adult; Carbamazepine; Epilepsy; Epilepsy, Absence; Female; Humans; Phenobarbital; Tuberous Sclerosis | 1981 |
Some behavioral effects of antiepileptic drugs during acute and prolonged treatment in the rat.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Discrimination Learning; Dose-Response Relationship, Drug; Drug Tolerance; Motor Skills; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1981 |
[The distribution of drugs between plasma, brain and cerebrospinal fluid in the human].
Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Carbamazepine; Diazepam; Humans; Lithium; Nordazepam; Phenobarbital; Phenytoin; Primidone; Protein Binding; Psychotropic Drugs; Serum Albumin; Sulfamerazine | 1982 |
Two antiepileptic drugs for intractable epilepsy with complex-partial seizures.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy, Temporal Lobe; Humans; Phenobarbital; Phenytoin; Primidone; Valproic Acid | 1982 |
Simultaneous very fast liquid-chromatographic analysis of ethosuximide, primidone, phenobarbital, phenytoin, and carbamazepine in serum.
Topics: Carbamazepine; Chromatography, Liquid; Economics; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1983 |
[Monitoring therapy by analysis of the drug concentration of saliva].
Topics: Anticonvulsants; Carbamazepine; Humans; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Saliva | 1983 |
A rapid procedure for the simultaneous estimation of the anticonvulsant drugs, ethosuximide, phenobarbitone, phenytoin, and carbamazepine in serum using high-pressure liquid chromatography.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin | 1983 |
Simultaneous liquid chromatographic determination of chloramphenicol and antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, and primidone) in plasma.
Topics: Adult; Anticonvulsants; Carbamazepine; Chloramphenicol; Chromatography, High Pressure Liquid; Drug Interactions; Humans; Male; Phenobarbital; Phenytoin; Primidone | 1983 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Alcohol, other drugs and the fetus.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Dextropropoxyphene; Diazepam; Drug Synergism; Female; Fetal Alcohol Spectrum Disorders; Fetus; Humans; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy | 1982 |
Improved isocratic liquid-chromatographic simultaneous measurement of phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide, and N-desmethylmethsuximide in serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values; Succinimides | 1982 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
A study of the action of anticonvulsant drugs on an experimental model of epilepsy.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Electric Stimulation; Epilepsy; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1980 |
Some immunological reactions during chronic treatment with antiepileptic drugs.
Topics: Adult; Antibody Formation; B-Lymphocytes; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; HLA Antigens; Humans; Immunity, Cellular; Male; Phenobarbital; Phenytoin; T-Lymphocytes | 1981 |
Decreased serum 24,25-dihydroxyvitamin D concentration during long-term anticonvulsant therapy in adult epileptics.
Topics: Adolescent; Adult; Anticonvulsants; Calcifediol; Calcitriol; Carbamazepine; Ergocalciferols; Humans; Middle Aged; Phenobarbital; Phenytoin | 1982 |
Measurement of sodium valproate in serum by direct-insertion chemical-ionization/mass spectrometry.
Topics: Carbamazepine; Humans; Mass Spectrometry; Microchemistry; Phenobarbital; Valproic Acid | 1980 |
On-line liquid-chromatographic analysis for drugs in serum with the Technicon "FAST-LC" system: performance data for theophylline and for four commonly used anticonvulsants and their metabolites.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1980 |
[A gas-chromatographic method for the determination of carbamazepine, phenobarbital, phenytoin and primidone in the same extract of serum (author's transl)].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Temperature | 1980 |
Emit assays for five major anticonvulsant drugs. An evaluation of adaptations to two discrete kinetic analyzers.
Topics: Anticonvulsants; Autoanalysis; Carbamazepine; Chromatography, Gas; Cross Reactions; Ethosuximide; Evaluation Studies as Topic; Humans; Immunoenzyme Techniques; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone | 1980 |
Enzyme immunoassay of phenobarbital, phenytoin, primidone, carbamazepine and theophylline with the Abbott VP Bichromatic Analyzer.
Topics: Carbamazepine; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Theophylline | 1981 |
Monitoring of therapeutic serum concentrations of antiepileptic drugs by a newly developed gas chromatographic procedure and enzyme immunoassay (EMIT): a comparative study.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Quality Control | 1981 |
Stability of antiepileptic drug level in serum. Reliability of enzyme immunoassay method.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Time Factors | 1980 |
Anticonvulsant drugs determined by EMIT in spiked brain samples: a correlation with HPLC values.
Topics: Animals; Anticonvulsants; Brain Chemistry; Carbamazepine; Chromatography, High Pressure Liquid; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1982 |
Anticonvulsant action of phenobarbital, diazepam, carbamazepine, and diphenylhydantoin in the electroshock test in mice after lesion of hippocampal pyramidal cells with intracerebroventricular kainic acid.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Electroshock; Hippocampus; Injections, Intraventricular; Kainic Acid; Male; Mice; Mice, Inbred Strains; Phenobarbital; Phenytoin; Pyrrolidines; Rats; Seizures | 1982 |
Respiratory disease in patients with epilepsy on single-drug therapy with carbamazepine or phenobarbital.
Topics: Adolescent; Adult; Carbamazepine; Epilepsy; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Male; Middle Aged; Phenobarbital; Respiratory Tract Infections | 1982 |
Differences between the concentrations of antiepileptic drugs in normal and pathological human brain.
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Child; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1982 |
Induction effect of phenobarbital on carbamazepine-10,11-epoxide kinetics in the rhesus monkey.
Topics: Animals; Biotransformation; Carbamazepine; Kinetics; Macaca mulatta; Male; Phenobarbital | 1982 |
[Carbamazepine (Tegretol) poisoning].
Topics: Adult; Alcoholic Intoxication; Carbamazepine; Humans; Male; Phenobarbital | 1982 |
[Absence of hypoplasia of fingernails and toenails and terminal phalanges of hands and feet (author's transl)].
Topics: Abnormalities, Multiple; Animals; Brain Diseases; Carbamazepine; Cats; Child, Preschool; Cysts; Deafness; Diagnosis, Differential; Female; Finger Joint; Humans; Nails, Malformed; Phenobarbital; Syndrome; Toe Joint | 1980 |
Nonlinear kinetics of phenytoin in children.
Topics: Adolescent; Adult; Age Factors; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epidermolysis Bullosa; Epilepsy; Female; Half-Life; Humans; Infant; Kinetics; Male; Metabolic Clearance Rate; Migraine Disorders; Phenobarbital; Phenytoin | 1982 |
Carbamazepine does not prevent febrile seizures in phenobarbital failures.
Topics: Carbamazepine; Child, Preschool; Female; Humans; Infant; Male; Phenobarbital; Recurrence; Seizures, Febrile | 1982 |
Quantitative assessment of smooth-pursuit eye movements in healthy and epileptic subjects.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electrooculography; Epilepsy; Eye Movements; Humans; Intelligence; Phenobarbital; Phenytoin; Reflex, Abnormal | 1980 |
Rapid determination of anticonvulsant drugs by isothermal gas-liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Ethosuximide; Humans; Microchemistry; Phenobarbital; Phenytoin; Primidone | 1981 |
Induction effect of phenobarbital on the carbamazepine to carbamazepine-10, 11-epoxide pathway in rhesus monkeys.
Topics: Animals; Carbamazepine; Drug Interactions; Enzyme Induction; Glucaric Acid; Kinetics; Macaca mulatta; Models, Biological; Phenobarbital; Time Factors | 1981 |
[Influence of anti-epileptic drugs on blood lipid parameters: preliminary data].
Topics: Anticonvulsants; Carbamazepine; Cholesterol; Epilepsy; Humans; Lipids; Phenobarbital; Phenytoin; Triglycerides | 1981 |
Ictal effects of anticonvulsant medication withdrawal in epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsy; Humans; Middle Aged; Phenobarbital; Phenytoin; Primidone; Substance Withdrawal Syndrome | 1981 |
Rapid microanalysis of anticonvulsants by high-performance thin-layer chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Thin Layer; Humans; Phenobarbital; Phenytoin; Primidone; Reference Values | 1981 |
[Pharmacological influences on the brain level and transport of GABA. I) Effect of various antipileptic drugs on brain levels of GABA].
Topics: Animals; Biological Transport; Brain; Carbamazepine; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Mice; Phenobarbital; Phenytoin | 1981 |
Effect of anticonvulsant and antidepressant drugs on iodothyronines in serum.
Topics: Adult; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Dose-Response Relationship, Drug; Female; Humans; Male; Mianserin; Phenobarbital; Phenytoin; Primidone; Thyroid Hormones | 1980 |
Carbamazepine, phenytoin and phenobarbital do not influence brain catecholamine uptake, in vivo, in male rats.
Topics: Animals; Brain; Carbamazepine; Catecholamines; Hydroxydopamines; Male; Nomifensine; Norepinephrine; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile.
Topics: Aging; Animals; Carbamazepine; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
Role of carbamazepine in reducing polypharmacy in epilepsy.
Topics: Acetazolamide; Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1981 |
Systematic method of development in liquid chromatography applied to the determination of antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Solubility; Temperature | 1981 |
Spectrophotometric determination of phenytoin in the presence of other anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Diazepam; Humans; Phenobarbital; Phenytoin; Primidone; Spectrophotometry, Ultraviolet | 1981 |
[Diagnosis of osteopathy caused by antiepileptic drugs].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bone Diseases; Carbamazepine; Epilepsy; Female; Femur; Hand; Humans; Lumbar Vertebrae; Male; Middle Aged; Osteomalacia; Osteoporosis; Pelvis; Phenobarbital; Phenytoin; Radiography | 1981 |
Improvement in antiepileptic drug levels following reduction of intervals between clinic visits.
Topics: Adolescent; Adult; Anticonvulsants; Appointments and Schedules; Carbamazepine; Epilepsy; Ethosuximide; Female; Humans; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Primidone | 1980 |
Measurement of anticonvulsants in serum by reversed-phase ion-pair liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylbutyrates; Phenytoin; Primidone; Urea | 1980 |
Plasma high-density lipoprotein cholesterol in epileptics treated with various anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Cholesterol; Epilepsy; Female; Humans; Lipoproteins, HDL; Male; Middle Aged; Phenobarbital; Phenytoin; Triglycerides | 1980 |
Effect of activated charcoal on absorption and elimination of phenobarbitone, carbamazepine and phenylbutazone in man.
Topics: Adult; Carbamazepine; Charcoal; Female; Humans; Intestinal Absorption; Kinetics; Male; Phenobarbital; Phenylbutazone; Time Factors | 1980 |
Antiepileptic drug distribution in cerebral cortex, ammon's horn, and amygdala in man.
Topics: Adolescent; Adult; Amygdala; Anticonvulsants; Carbamazepine; Cerebral Cortex; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Primidone | 1980 |
Carbamazepine-induced leukocytosis.
Topics: Adult; Carbamazepine; Female; Humans; Leukocytosis; Neutrophils; Phenobarbital; Phenytoin; Seizures | 1980 |
Liquid-chromatographic method for simultaneous determination of phenytoin and 5-(4-hydroxyphenyl)-5-phenylhydantoin in plasma and urine.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Microchemistry; Phenobarbital; Phenytoin; Urine | 1980 |
Improved gas--liquid chromatographic method for the simultaneous determination of phenobarbital, phenytoin, carbamazepine and primidone in biological fluids.
Topics: Carbamazepine; Chromatography, Gas; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
High performance liquid chromatographic analysis of anti-convulsant drugs using radial compression columns.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
[A study of effects on antiepileptic drugs upon the hippocampal afterdischarge (author's transl)].
Topics: Animals; Anticonvulsants; Carbamazepine; Cats; Electric Stimulation; Female; Hippocampus; Male; Phenobarbital; Phenytoin; Seizures; Trimethadione | 1980 |
Rapid quantitative determination of underivatized carbamazepine, phenytoin, phenobarbital and p-hydroxyphenobarbital in biological fluids by packed column gas chromatography.
Topics: Adult; Carbamazepine; Chromatography, Gas; Epilepsy; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Phenobarbital; Phenytoin | 1980 |
[Biotransformation of some antiepileptic drugs (author's transl)].
Topics: Anticonvulsants; Biotransformation; Carbamazepine; Humans; Phenobarbital; Phenytoin; Primidone | 1980 |
Power spectral analysis of EEG characteristics during sleep in epileptics.
Topics: Adolescent; Adult; Carbamazepine; Circadian Rhythm; Electroencephalography; Epilepsy; Ethosuximide; Female; Humans; Infant; Male; Monitoring, Physiologic; Phenobarbital; Phenytoin; Primidone; Sleep, REM | 1981 |
Validation of a quick modeling program generating clearance estimates at steady state for routine therapeutic drug monitoring.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Monitoring; Humans; Metabolic Clearance Rate; Models, Biological; Phenobarbital; Software; Valproic Acid | 1995 |
Anticonvulsant hypersensitivity syndrome.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Female; Fever; Humans; Lymphatic Diseases; Male; Phenobarbital; Phenytoin; Prognosis; Syndrome | 1995 |
Influence of BAY k-8644, a calcium channel agonist, on the anticonvulsant activity of conventional anti-epileptics against electroconvulsions in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Drug Therapy, Combination; Electroshock; Flunarizine; Male; Mice; Phenobarbital; Valproic Acid | 1995 |
Automated analysis of free and total concentrations of three antiepileptic drugs in plasma with on-line dialysis and high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dialysis; Epilepsy; Humans; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 1995 |
Cytokine production in blood mononuclear cells from epileptic patients.
Topics: Adolescent; Adult; Carbamazepine; Cytokines; Epilepsy; Female; Humans; Interleukin-1; Interleukin-2; Interleukin-6; Leukocytes, Mononuclear; Male; Middle Aged; Mitogens; Phenobarbital; Valproic Acid | 1995 |
Interactions of phenobarbital and phenytoin with carbamazepine and its metabolites' concentrations, concentration ratios, and level/dose ratios in epileptic children.
Topics: Biotransformation; Carbamazepine; Child; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Male; Oxidoreductases; Phenobarbital; Phenytoin | 1995 |
The clinical pharmacology of antiepileptic drugs.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Humans; Phenobarbital; Phenytoin; Reference Values; Valproic Acid | 1995 |
Is there a pathophysiological and therapeutic link between panic disorder and epilepsy?
Topics: Adult; Brain; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Magnetic Resonance Imaging; Panic Disorder; Phenobarbital; Phenytoin | 1995 |
Aspirin and anticonvulsant interaction.
Topics: Animals; Aspirin; Carbamazepine; Disease Models, Animal; Drug Synergism; Electroshock; Female; Male; Phenobarbital; Phenytoin; Rats; Seizures | 1995 |
Reduced carnitine and antiepileptic drugs: cause relationship or co-existence?
Topics: Adolescent; Anticonvulsants; Carbamazepine; Carnitine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Longitudinal Studies; Male; Phenobarbital; Valproic Acid | 1995 |
The stability of anticonvulsant drugs in whole blood.
Topics: Anticonvulsants; Carbamazepine; Drug Stability; Drug Storage; Humans; Phenobarbital; Phenytoin; Temperature; Valproic Acid | 1994 |
Effects of the peptide BCH-325 upon the efficacy of common antiepileptic drugs.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Carbamazepine; Diazepam; Drug Interactions; Endorphins; gamma-Aminobutyric Acid; Male; Mice; Mice, Inbred ICR; Molecular Sequence Data; Peptide Fragments; Phenobarbital; Phenytoin; Seizures; Sodium Channels; Synaptic Transmission; Valproic Acid | 1994 |
Do enzyme inducers modify haloperidol decanoate rate of release?
Topics: Antipsychotic Agents; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Humans; Phenobarbital; Schizophrenia | 1994 |
Competitive NMDA receptor antagonists enhance the antielectroshock activity of various antiepileptics.
Topics: 2-Amino-5-phosphonovalerate; Animals; Anticonvulsants; Avoidance Learning; Behavior, Animal; Carbamazepine; Drug Synergism; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Seizures | 1993 |
Changes in phenamine effects after repeated treatment and subsequent withdrawal of phenobarbital, carbamazepine and a combination of both.
Topics: Amphetamine; Animals; Carbamazepine; Drug Interactions; Drug Tolerance; Male; Phenobarbital; Rats; Rats, Wistar; Stereotyped Behavior; Substance-Related Disorders | 1993 |
Enhanced differential diagnosis of anticonvulsant hypersensitivity reactions by an integrated Bayesian and biochemical approach.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Bayes Theorem; Carbamazepine; Cell Death; Child; Diagnosis, Differential; Drug Eruptions; Female; Humans; Lymphocytes; Male; Middle Aged; Phenobarbital; Phenytoin; Predictive Value of Tests; Sensitivity and Specificity | 1994 |
Sex hormones, gonadotropins and prolactin in male epileptic subjects in remission: role of the epileptic syndrome and of antiepileptic drugs.
Topics: Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dihydrotestosterone; Epilepsies, Partial; Epilepsy, Generalized; Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Phenobarbital; Phenytoin; Prolactin; Sex Hormone-Binding Globulin; Testosterone; Thyrotropin-Releasing Hormone | 1994 |
Diagnosis and treatment.
Topics: Adolescent; Carbamazepine; Child; Developing Countries; Diagnosis, Differential; Electroencephalography; Epilepsy; Female; Humans; Kenya; Male; Medical History Taking; Phenobarbital; Tomography, X-Ray Computed | 1994 |
Epilepsy treatment in The Netherlands. Comparison of matched groups of two medical centres.
Topics: Adolescent; Adult; Carbamazepine; Diazepam; Epilepsy; Ethosuximide; Female; gamma-Aminobutyric Acid; Humans; Male; Netherlands; Phenobarbital; Phenytoin; Primidone; Quality of Health Care; Statistics, Nonparametric; Treatment Outcome; Valproic Acid; Vigabatrin | 1994 |
Synthesis of polymer-coated mixed-functional packing materials for direct analysis of drug-containing serum and plasma by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Polymers; Silicon Dioxide | 1994 |
Simple and accurate high-performance liquid chromatographic method for the measurement of three antiepileptics in therapeutic drug monitoring.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1993 |
Creatinine metabolism impairment by an anticonvulsant drug, phenacemide.
Topics: Adult; Anticonvulsants; Benzeneacetamides; Carbamazepine; Creatinine; Epilepsy, Temporal Lobe; Glomerular Filtration Rate; Humans; Male; Phenobarbital; Urea | 1994 |
Measurement of lamotrigine under conditions measuring phenobarbitone, phenytoin, and carbamazepine using reversed-phase high-performance liquid chromatography at dual wavelengths.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamotrigine; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Triazines | 1994 |
Simultaneous determination of felbamate, primidone, phenobarbital, carbamazepine, two carbamazepine metabolites, phenytoin, and one phenytoin metabolite in human plasma by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Felbamate; Humans; Phenobarbital; Phenylcarbamates; Phenytoin; Primidone; Propylene Glycols; Quality Control; Regression Analysis; Spectrophotometry, Ultraviolet | 1994 |
Characterization of the pharmacodynamics of several antiepileptic drugs in a direct cortical stimulation model of anticonvulsant effect in the rat.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Drug Evaluation, Preclinical; Female; Oxazepam; Phenobarbital; Rats; Rats, Wistar; Seizures | 1994 |
[Repetitive serum determinations of anticonvulsants in epileptic patients].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Chronic Disease; Epilepsy; Female; Humans; Middle Aged; Phenobarbital; Phenytoin; Time Factors; Treatment Refusal | 1993 |
Chronological changes of MRI findings on striatal damage after acute cyanide intoxication: pathogenesis of the damage and its selectivity, and prevention for neurological sequelae: a case report.
Topics: Adult; Basal Ganglia; Brain Diseases; Carbamazepine; Corpus Striatum; Epilepsy, Temporal Lobe; Humans; Magnetic Resonance Imaging; Male; Nifedipine; Phenobarbital; Phenytoin; Potassium Cyanide; Suicide, Attempted | 1993 |
The use of antiepileptic drug levels in children: a survey of Canadian pediatric neurologists.
Topics: Adolescent; Anticonvulsants; Attitude of Health Personnel; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Valproic Acid | 1993 |
Pharmacological characterization of phenytoin-resistant amygdala-kindled rats, a new model of drug-resistant partial epilepsy.
Topics: Amino Acids; Aminocaproates; Amygdala; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Resistance; Electric Stimulation; Electrodes, Implanted; Epilepsies, Partial; Female; Kindling, Neurologic; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Valproic Acid; Vigabatrin | 1993 |
Possible interaction between phenobarbital, carbamazepine and itraconazole.
Topics: Adult; Aspergillosis; Brain Diseases; Carbamazepine; Drug Interactions; Enzyme Induction; Humans; Itraconazole; Male; Phenobarbital; Seizures | 1993 |
Simultaneous determination of carbamazepine, phenytoin, phenobarbital, primidone and their principal metabolites by high-performance liquid chromatography with photodiode-array detection.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Hydrogen-Ion Concentration; Immunoenzyme Techniques; Phenobarbital; Phenytoin; Primidone; Saliva; Spectrophotometry, Ultraviolet | 1993 |
[Lafora disease. Report of a new case diagnosed by biopsy from the axillary skin].
Topics: Axilla; Biopsy; Carbamazepine; Child; Eccrine Glands; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Humans; Inclusion Bodies; Male; Phenobarbital; Seizures; Skin; Valproic Acid | 1993 |
Pharmacokinetic interaction of zonisamide in rats. Effect of zonisamide on other antiepileptics.
Topics: Animals; Anticonvulsants; Blood Proteins; Carbamazepine; Drug Interactions; Erythrocytes; In Vitro Techniques; Isoxazoles; Male; Phenobarbital; Phenytoin; Protein Binding; Rats; Rats, Wistar; Valproic Acid; Zonisamide | 1993 |
Use of Fourier transform infrared spectroscopy for the simultaneous quantitative detection of metal carbonyl tracers suitable for multilabel immunoassays.
Topics: Carbamazepine; Cobalt; Evaluation Studies as Topic; Fourier Analysis; Humans; Immunoassay; Manganese; Organometallic Compounds; Phenobarbital; Spectrophotometry, Infrared | 1993 |
Daytime sleepiness in epileptic patients on long-term monotherapy: MSLT, clinical and psychometric assessment.
Topics: Adolescent; Adult; Analysis of Variance; Carbamazepine; Electroencephalography; Epilepsy; Humans; Male; Neuropsychological Tests; Phenobarbital; Polysomnography; Sleep; Surveys and Questionnaires; Time Factors | 1993 |
Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s)
Topics: Adult; Animals; Anticonvulsants; Autoantibodies; Autoantigens; Carbamazepine; Cell Line; Cross Reactions; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Drug Hypersensitivity; Endoplasmic Reticulum; Epilepsies, Partial; Epilepsy, Tonic-Clonic; Humans; Inactivation, Metabolic; Isoenzymes; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats | 1993 |
Five years of anticonvulsant monitoring on site at the epilepsy clinic.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; Outpatient Clinics, Hospital; Phenobarbital; Phenytoin; Prospective Studies; Scotland; Time Factors; Valproic Acid | 1993 |
Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in the serum: analysis of autoptic specimens from 51 epileptic patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autopsy; Brain Chemistry; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Tissue Distribution | 1993 |
An audit of therapeutic drug monitoring of anticonvulsants.
Topics: Adult; Anticonvulsants; Carbamazepine; Child; Drug Monitoring; Epilepsy; Humans; Medical Audit; Northern Ireland; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cells, Cultured; Clofibrate; Clotrimazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Induction; Liver; Male; Mixed Function Oxygenases; Omeprazole; Phenobarbital; Phenytoin; Pyrrolidinones; Rifampin; Steroid Hydroxylases | 1995 |
A model for estimating individualized valproate clearance values in children.
Topics: Administration, Oral; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Metabolic Clearance Rate; Models, Theoretical; Pharmacokinetics; Phenobarbital; Phenytoin; Valproic Acid | 1995 |
Pharmacology of cortical epileptic afterdischarges in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Dimethyl Sulfoxide; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Epilepsies, Myoclonic; Epilepsy; Male; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Severity of Illness Index; Valproic Acid | 1996 |
Effect of valproate on cerebral metabolism and blood flow: an 18F-2-deoxyglucose and 15O water positron emission tomography study.
Topics: Adult; Brain; Carbamazepine; Cerebrovascular Circulation; Deoxyglucose; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Fluorodeoxyglucose F18; Glucose; Humans; Male; Oxygen Radioisotopes; Phenobarbital; Phenytoin; Tomography, Emission-Computed; Valproic Acid; Water | 1996 |
Increasing-current electroshock seizure test: a new method for assessment of anti- and pro-convulsant activities of drugs in mice.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Carbamazepine; Convulsants; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; Ear; Electrodes; Electroshock; Ethosuximide; Injections, Intravenous; Male; Mice; Morphine; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1996 |
Seizure control after chronic pharmacotherapy in epileptic disorders beginning after 40 years of age.
Topics: Adult; Age of Onset; Aged; Carbamazepine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Primidone | 1995 |
[Study of the influence of anticonvulsant treatment on thyroid function].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Enzyme-Linked Immunosorbent Assay; Epilepsy; Female; Humans; Hypothyroidism; Male; Middle Aged; Phenobarbital; Phenytoin; Prospective Studies; Thyroid Gland; Thyroid Hormones; Thyrotropin; Valproic Acid | 1995 |
Comparative effects of carbamazepine and carbamazepine-10,11-epoxide on hepatic cytochromes P450 in the rat.
Topics: Animals; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Male; Microsomes, Liver; Phenobarbital; Rats; Steroid Hydroxylases | 1996 |
Comparing antiepileptic drugs.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Humans; Phenobarbital; Valproic Acid | 1996 |
Clearance of phenytoin and valproic acid is affected by a small body weight reduction in an epileptic obese patient: a case study.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Half-Life; Humans; Metabolic Clearance Rate; Obesity; Phenobarbital; Phenytoin; Valproic Acid; Weight Loss | 1996 |
[The effects of phenobarbital, valproic acid and carbamazepine on the serum lipids and lipoproteins in a pediatric population].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Lipids; Lipoproteins; Male; Phenobarbital; Time Factors; Valproic Acid | 1996 |
The necessity of adjusting the dosage of zonisamide when coadministered with other anti-epileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Humans; Isoxazoles; Phenobarbital; Phenytoin; Valproic Acid; Zonisamide | 1996 |
Detection of carbamazepine drug interaction by multiple peak approach screening using routine clinical pharmacokinetic data.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Infant; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Software; Valproic Acid | 1996 |
Steady state pharmacokinetics of carbamazepine-phenobarbital interaction in patients with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Phenobarbital; Tablets | 1996 |
Anticonvulsant drug effects on spontaneous thalamocortical rhythms in vitro: phenytoin, carbamazepine, and phenobarbital.
Topics: Animals; Carbamazepine; Cerebral Cortex; Dose-Response Relationship, Drug; In Vitro Techniques; Mice; Mice, Inbred ICR; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley; Thalamus | 1996 |
Quantitative analysis of mixtures of metal-carbonyl complexes by Fourier-transform infrared spectroscopy: application to the simultaneous double immunoassay of antiepileptic drugs by the nonisotopic carbonyl metalloimmunoassay method.
Topics: Animals; Anticonvulsants; Carbamazepine; Evaluation Studies as Topic; Haptens; Humans; Immunoassay; Molecular Structure; Organometallic Compounds; Phenobarbital; Phenytoin; Spectroscopy, Fourier Transform Infrared | 1996 |
[Epileptic seizures during sleep].
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain; Carbamazepine; Electroencephalography; Epilepsy, Generalized; Female; Humans; Male; Middle Aged; Phenobarbital; Sleep; Valproic Acid | 1996 |
Elevated plasma alpha 1-acid glycoprotein levels: lack of connection to resistance to vecuronium blockade induced by anticonvulsant therapy.
Topics: Adult; Alprazolam; Anticonvulsants; Atropine; Biomarkers; Carbamazepine; Drug Interactions; Drug Resistance; Humans; Hydroxyzine; Hypnotics and Sedatives; Middle Aged; Neuromuscular Nondepolarizing Agents; Neurosurgery; Orosomucoid; Phenobarbital; Phenytoin; Vecuronium Bromide | 1997 |
Population pharmacokinetics of felbamate in children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Felbamate; Humans; Infant; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Seizures; Valproic Acid | 1997 |
Hippocampal and cerebellar extracellular amino acids during pilocarpine-induced seizures in freely moving rats.
Topics: Amino Acids; Animals; Aspartic Acid; Carbamazepine; Cerebellum; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Microdialysis; Phenobarbital; Pilocarpine; Rats; Rats, Wistar; Seizures | 1997 |
Mechanism for reduction of serum folate by antiepileptic drugs during prolonged therapy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Demography; Epilepsy; Female; Folic Acid; Folic Acid Deficiency; Humans; Infant; Isoxazoles; Male; Phenobarbital; Time Factors; Valproic Acid; Zonisamide | 1997 |
Influence of isradipine, niguldipine and dantrolene on the anticonvulsive action of conventional antiepileptics in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dantrolene; Dihydropyridines; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Female; Isradipine; Lethal Dose 50; Mice; Motor Activity; Phenobarbital; Phenytoin; Random Allocation; Seizures; Valproic Acid | 1997 |
[Sturge-Weber syndrome: experience with 14 cases].
Topics: Anticonvulsants; Brain; Carbamazepine; Epilepsy; Female; Humans; Infant; Magnetic Resonance Imaging; Male; Medical Records; Phenobarbital; Retrospective Studies; Sturge-Weber Syndrome; Tomography, X-Ray Computed; Valproic Acid | 1997 |
N6-2-(4-aminophenyl)ethyl-adenosine enhances the anticonvulsive activity of antiepileptic drugs.
Topics: Adenosine; Animals; Anticonvulsants; Body Temperature; Carbamazepine; Darkness; Drug Synergism; Electroshock; Female; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Purinergic P1 Receptor Agonists; Valproic Acid | 1997 |
[Serum digitoxin in concomitant use of antiepileptics in routine therapy].
Topics: Anticonvulsants; Antidepressive Agents; Carbamazepine; Digitoxin; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Lithium Compounds; Male; Phenobarbital; Phenytoin | 1997 |
A rapid in vitro assay for evaluation of metabolism-dependent cytotoxicity of antiepileptic drugs on isolated human lymphocytes.
Topics: Acetaminophen; Animals; Anticonvulsants; Biological Assay; Carbamazepine; Cell Count; Cell Survival; Female; Fluorescence; Humans; In Vitro Techniques; Lymphocytes; Microsomes, Liver; Phenobarbital; Phenytoin; Rabbits | 1997 |
Changes in serum lipids and lipoproteins in epileptic children treated with anticonvulsants.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Hyperlipidemias; Lipids; Lipoproteins; Male; Phenobarbital; Valproic Acid | 1997 |
Anticonvulsant usage is associated with an increased risk of procarbazine hypersensitivity reactions in patients with brain tumors.
Topics: Adult; Anticonvulsants; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carbamazepine; Cohort Studies; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Procarbazine; Retrospective Studies; Valproic Acid | 1997 |
Extrashot-ODS, a syringe-type minicolumn sample injector for a reversed-phase high-performance liquid chromatographic column. Application to antiepileptics in human sera.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Epilepsy; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1997 |
Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of zonisamide.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Electrophoresis, Capillary; Fluorescence Polarization Immunoassay; Humans; Isoxazoles; Phenobarbital; Phenytoin; Zonisamide | 1997 |
Biotin biotransformation to bisnorbiotin is accelerated by several peroxisome proliferators and steroid hormones in rats.
Topics: Analysis of Variance; Animals; Anticonvulsants; Biotin; Biotransformation; Carbamazepine; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Clofibrate; Dehydroepiandrosterone; Dexamethasone; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; Male; Microbodies; Phenobarbital; Phenytoin; Radiometry; Rats; Rats, Sprague-Dawley; Steroids | 1997 |
Anticonvulsant cross-sensitivity.
Topics: Anticonvulsants; Carbamazepine; Cross Reactions; Drug Hypersensitivity; Humans; Phenobarbital; Phenytoin | 1997 |
If a first antiepileptic drug fails to control a child's epilepsy, what are the chances of success with the next drug?
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cohort Studies; Drug Administration Schedule; Epilepsy; Follow-Up Studies; Humans; Nova Scotia; Phenobarbital; Phenytoin; Prognosis; Remission Induction; Treatment Failure | 1997 |
Population-based investigation of valproic acid relative clearance using nonlinear mixed effects modeling: influence of drug-drug interaction and patient characteristics.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; GABA Agents; Humans; Infant; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Phenobarbital; Valproic Acid | 1997 |
[Optimisation of epilepsy monotherapy (clinico-pharmacological study)].
Topics: Anticonvulsants; Barbiturates; Carbamazepine; Chromatography, High Pressure Liquid; Electroencephalography; Epilepsy; Follow-Up Studies; Half-Life; Humans; Phenobarbital; Phenytoin; Treatment Outcome | 1997 |
Disturbances in biotin metabolism in children undergoing long-term anticonvulsant therapy.
Topics: Anticonvulsants; Biotin; Carbamazepine; Child; Female; Humans; Male; Phenobarbital; Phenytoin; Valerates | 1998 |
Treatment of the epileptic patient in the dental office.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dental Care for Chronically Ill; Emergencies; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Female; Humans; Liability, Legal; Male; Medical History Taking; Middle Aged; Patient Care Planning; Phenobarbital; Phenytoin; Valproic Acid | 1998 |
Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?
Topics: Abnormalities, Drug-Induced; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Arrhythmias, Cardiac; Carbamazepine; Female; Fetus; Heart; Humans; Hypoxia; Mice; Mice, Inbred C57BL; Phenobarbital; Phenytoin; Pregnancy; Rats; Trimethadione | 1998 |
The influence of L-NG-nitroarginine methyl ester, an inhibitor of nitric oxide synthase, upon the anticonvulsive activity of conventional antiepileptic drugs against maximal electroshock in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Drug Antagonism; Electroshock; Enzyme Inhibitors; Female; Memory; Mice; Motor Activity; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 1998 |
Detection of a drug-drug interaction on population-based phenobarbitone clearance using nonlinear mixed-effects modeling.
Topics: Adolescent; Adult; Age Factors; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Phenobarbital; Prospective Studies; Regression Analysis; Sex Factors; Valproic Acid | 1998 |
Does antiepileptic therapy affect immune response?
Topics: Adolescent; Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Cytokines; Drug Therapy, Combination; Epilepsy; Felbamate; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Lamotrigine; Male; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Receptors, Interleukin-2; Triazines; Valproic Acid | 1998 |
Anticonvulsant drug effects in the direct cortical ramp-stimulation model in rats: comparison with conventional seizure models.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Female; Phenobarbital; Rats; Rats, Wistar; Seizures; Time Factors; Valproic Acid | 1998 |
The incorporation of lamotrigine into the routine automated sequential trace enrichment of dialysates assay of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Triazines | 1998 |
Changes of the EEG paroxysmal pattern during felbamate therapy in Lennox-Gastaut syndrome: a case report.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Carbamazepine; Clobazam; Drug Therapy, Combination; Electroencephalography; Epilepsy; Felbamate; Female; Humans; Phenobarbital; Phenylcarbamates; Propylene Glycols; Syndrome; Valproic Acid | 1998 |
Phenytoin, phenobarbital, and midazolam fail to stop status epilepticus-like activity induced by low magnesium in rat entorhinal slices, but can prevent its development.
Topics: Animals; Anticonvulsants; Carbamazepine; Culture Techniques; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Entorhinal Cortex; Magnesium; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Status Epilepticus | 1998 |
Vigabatrin aggravates absences and absence status.
Topics: Adult; Anticonvulsants; Asphyxia; Brain Damage, Chronic; Carbamazepine; Drug Therapy, Combination; Electroencephalography; Epilepsy, Absence; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid; Humans; Male; Phenobarbital; Vigabatrin | 1998 |
Serum lipids and lipoproteins in patients treated with antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Apolipoprotein A-I; Apolipoproteins B; Carbamazepine; Cholesterol; Epilepsy; Female; Humans; Lipids; Lipoprotein(a); Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phenobarbital; Time Factors; Triglycerides; Valproic Acid | 1998 |
Comparison between premortem and postmortem serum concentrations of phenobarbital, phenytoin, carbamazepine and its 10,11-epoxide metabolite in institutionalized patients with epilepsy.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hospitalization; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postmortem Changes; Time Factors | 1999 |
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency | 1999 |
Anticonvulsant and neurotoxic effects of intracerebroventricular injection of phenytoin, phenobarbital and carbamazepine in an amygdala-kindling model of epilepsy in the rat.
Topics: Amygdala; Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Injections, Intraventricular; Kindling, Neurologic; Male; Nervous System; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Time Factors | 1999 |
Lamotrigine drug interactions in a TDM material.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Triazines; Valproic Acid | 1999 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics | 1999 |
Effect of adenosinergic modulation on the anticonvulsant effect of phenobarbitone and carbamazepine.
Topics: Adenosine; Animals; Anticonvulsants; Carbamazepine; Convulsants; Drug Combinations; Male; Pentylenetetrazole; Phenobarbital; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Seizures; Theophylline; Xanthines | 1999 |
The management of epilepsy in a hospital for people with a learning disability.
Topics: Acetates; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Utilization; Epilepsy; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Health Surveys; Hospitals, Psychiatric; Humans; Lamotrigine; Learning Disabilities; Male; Middle Aged; Phenobarbital; Triazines; United Kingdom; Vigabatrin | 1999 |
Clinical experience with new antiepileptic drugs: antiepileptic drugs in Europe.
Topics: Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Cross-Cultural Comparison; Drug Approval; Drug Monitoring; Drug Prescriptions; Epilepsy; Europe; History, 20th Century; Humans; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 1999 |
NMDA- but not kainate-mediated events reduce efficacy of some antiepileptic drugs against generalized tonic-clonic seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy, Tonic-Clonic; Kainic Acid; Male; Mice; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, N-Methyl-D-Aspartate; Valproic Acid | 1999 |
Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Hypothyroidism; Male; Phenobarbital; Thyrotropin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine; Valproic Acid | 1999 |
The role of technical, biological, and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. VII. Seasonal influences on anticonvulsant drug actions in mouse models of generalized seizures.
Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroshock; Male; Mice; Periodicity; Phenobarbital; Seasons; Seizures; Valproic Acid | 2000 |
Effects of standard anticonvulsant drugs on different patterns of epileptiform discharges induced by 4-aminopyridine in combined entorhinal cortex-hippocampal slices.
Topics: 4-Aminopyridine; Animals; Anticonvulsants; Carbamazepine; Entorhinal Cortex; Epilepsies, Partial; Female; gamma-Aminobutyric Acid; Hippocampus; Hypnotics and Sedatives; Male; Pentobarbital; Phenobarbital; Phenytoin; Prohibitins; Rats; Rats, Wistar; Valproic Acid | 2000 |
Improved sexual function in three men taking lamotrigine for epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Epilepsies, Partial; Epilepsy, Complex Partial; Epilepsy, Temporal Lobe; Erectile Dysfunction; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Male; Middle Aged; Phenobarbital; Phenytoin; Sexual Dysfunctions, Psychological; Triazines; Valproic Acid | 2000 |
Anticonvulsant induced osteomalacia.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Infant; Male; Osteomalacia; Phenobarbital; Risk Factors; Vitamin D Deficiency | 2000 |
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12 | 2000 |
Changes in bone turnover and deoxypyridinoline levels in epileptic patients.
Topics: Adult; Alkaline Phosphatase; Amino Acids; Anticonvulsants; Bone and Bones; Calcium; Carbamazepine; Case-Control Studies; Epilepsy; Female; Humans; Male; Osteocalcin; Phenobarbital; Phenytoin; Sex Factors; Vitamin D | 2000 |
[Drug resistant epilepsy in Senegal: therapeutic, clinical and socioeconomic factors].
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Resistance; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Senegal; Socioeconomic Factors; Valproic Acid | 1999 |
Repeated acute testing of anticonvulsant drugs in amygdala kindled rats: increase in anticonvulsant but decrease in adverse effect potential.
Topics: Amygdala; Animals; Anticonvulsants; Ataxia; Behavior, Animal; Carbamazepine; Disease Models, Animal; Drug Synergism; Electric Stimulation; Epilepsy; Female; Kindling, Neurologic; Periodicity; Phenobarbital; Rats; Rats, Wistar; Seasons; Valproic Acid | 2000 |
The effects on lipid and apolipoprotein serum levels of long-term carbamazepine, valproic acid and phenobarbital therapy in children with epilepsy.
Topics: Anticonvulsants; Apolipoprotein A-I; Apolipoproteins; Apolipoproteins B; Carbamazepine; Child; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Epilepsy; Female; Humans; Lipids; Male; Phenobarbital; Reference Values; Time Factors; Triglycerides; Valproic Acid | 2000 |
Interaction of carbamazepine and phenobarbital in rabbits.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Interactions; Phenobarbital; Rabbits | 2000 |
Investigation of phenobarbital-carbamazepine-valproic acid interactions using population pharmacokinetic analysis for optimisation of antiepileptic drug therapy: an overview.
Topics: Adolescent; Adult; Anticonvulsants; Biomarkers; Body Weight; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Infant; Metabolic Clearance Rate; Phenobarbital; Reference Values; Regression Analysis; Valproic Acid | 2000 |
Renal tubular function in patients receiving anticonvulsant therapy: a long-term study.
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Follow-Up Studies; Humans; Kidney Diseases; Kidney Function Tests; Kidney Tubules; Longitudinal Studies; Male; Phenobarbital; Valproic Acid | 2000 |
Cloud-point extraction for the determination of the free fraction of antiepileptic drugs in blood plasma and saliva.
Topics: Animals; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Female; Humans; Phenobarbital; Rabbits; Saliva; Spectrophotometry, Ultraviolet | 2000 |
Effects of antiepileptic drugs on evoked potentials in epileptic children.
Topics: Adolescent; Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Evoked Potentials, Auditory, Brain Stem; Evoked Potentials, Visual; Female; Humans; Male; Phenobarbital; Prospective Studies; Valproic Acid | 2000 |
A novel lymphocyte toxicity assay to assess drug hypersensitivity syndromes.
Topics: Adolescent; Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Case-Control Studies; Cell Survival; Chemistry, Clinical; Child; Cohort Studies; Coloring Agents; Drug Hypersensitivity; Family Health; Female; HIV Seropositivity; Humans; Lamotrigine; Lymphocytes; Male; Mice; Microsomes, Liver; Middle Aged; Mitochondria; Phenobarbital; Phenytoin; Sensitivity and Specificity; Succinate Dehydrogenase; Sulfadiazine; Sulfamethoxazole; Sulfonamides; Tetrazolium Salts; Thiazoles; Time Factors; Triazines; Trimethoprim; Trypan Blue | 2000 |
Acute intermittent porphyria, seizures, and antiepileptic drugs: a report on a 3-year-old Nigerian boy.
Topics: Anticonvulsants; Carbamazepine; Child, Preschool; Epilepsy, Generalized; Humans; Male; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Severity of Illness Index | 2001 |
Comparison the cognitive effect of anti-epileptic drugs in seizure-free children with epilepsy before and after drug withdrawal.
Topics: Anticonvulsants; Carbamazepine; Child; Cognition; Epilepsy; Event-Related Potentials, P300; Female; Humans; Male; Phenobarbital; Retrospective Studies; Valproic Acid; Wechsler Scales | 2001 |
The teratogenicity of anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Case-Control Studies; Congenital Abnormalities; Epilepsy; Face; Female; Fetal Growth Retardation; Fingers; Humans; Infant, Newborn; Logistic Models; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 2001 |
Pharmacokinetic interactions among phenobarbital, carbamazepine, and valproic acid in pediatric Japanese patients: clinical considerations on steady-state serum concentration-dose ratios.
Topics: Adolescent; Anticonvulsants; Biological Availability; Carbamazepine; Child; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Japan; Phenobarbital; Retrospective Studies; Valproic Acid | 2000 |
Protease inhibitors and anticonvulsants.
Topics: Anti-HIV Agents; Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; HIV Infections; HIV Protease Inhibitors; Humans; Isoenzymes; Phenobarbital; Phenytoin | 1997 |
Effect of Antiepileptic drugs on plasma lipoprotein (a) and other lipid levels in childhood.
Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cholesterol, HDL; Epilepsy; Female; Humans; Infant; Lipoproteins; Male; Phenobarbital; Triglycerides; Valproic Acid | 2001 |
Population pharmacokinetics of carbamazepine in Singapore epileptic patients.
Topics: Adolescent; Adult; Analysis of Variance; Anticonvulsants; Bayes Theorem; Carbamazepine; Child; Child, Preschool; China; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Middle Aged; Models, Biological; Models, Statistical; Phenobarbital; Predictive Value of Tests; Singapore | 2001 |
Incidence of drug-induced aggravation in benign epilepsy with centrotemporal spikes.
Topics: Acute Disease; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combination; Electroencephalography; Epilepsy, Rolandic; Female; Follow-Up Studies; Humans; Incidence; Male; Phenobarbital; Retrospective Studies | 2001 |
Course of chronic focal epilepsy resistant to anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Cluster Analysis; Disease Progression; Documentation; Drug Administration Schedule; Drug Resistance; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Male; Periodicity; Phenobarbital; Phenytoin | 2001 |
Carbamazepine in phenobarbital-nonresponders: experience with ten preterm infants.
Topics: Administration, Oral; Anticonvulsants; Carbamazepine; Electroencephalography; Female; Follow-Up Studies; Humans; Infant, Low Birth Weight; Infant, Newborn; Infant, Premature; Male; Phenobarbital; Prospective Studies; Spasms, Infantile; Treatment Failure; Treatment Outcome | 2001 |
Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4.
Topics: Adult; Aged; Animals; Anticonvulsants; Carbamazepine; Cell Line; Cholagogues and Choleretics; Cholesterol; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Female; Humans; Hydroxycholesterols; Insecta; Kinetics; Male; Microsomes; Middle Aged; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Recombinant Proteins; Ursodeoxycholic Acid | 2001 |
[Lafora's disease: one of the causes for drug-resistant epilepsy in adolescence].
Topics: Adolescent; Age Factors; Anticonvulsants; Carbamazepine; Child; Drug Resistance; Drug Therapy, Combination; Electroencephalography; Female; Follow-Up Studies; Humans; Lafora Disease; Phenobarbital; Time Factors; Valproic Acid | 2001 |
Serum lipid changes during anticonvulsive treatment serum lipids in epileptic children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Enzyme Induction; Epilepsy; Female; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipids; Liver; Male; Phenobarbital; Triglycerides; Valproic Acid | 2001 |
[Treatment of febrile convulsions].
Topics: Age Factors; Analgesics, Non-Narcotic; Anticonvulsants; Carbamazepine; Child, Preschool; Diazepam; Double-Blind Method; Female; Humans; Infant; Male; Phenobarbital; Phenytoin; Prospective Studies; Randomized Controlled Trials as Topic; Recurrence; Risk Factors; Seizures, Febrile; Time Factors; Valproic Acid | 2002 |
The effects of antiepileptic drugs on spatial learning and hippocampal protein kinase C gamma in immature rats.
Topics: Animals; Anticonvulsants; Blotting, Western; Carbamazepine; Hippocampus; Immunohistochemistry; Isoenzymes; Learning; Male; Memory Disorders; Phenobarbital; Protein Kinase C; Rats; Rats, Wistar; Space Perception; Valproic Acid | 2002 |
Determination of lamotrigine simultaneously with carbamazepine, carbamazepine epoxide, phenytoin, phenobarbital, and primidone in human plasma by SPME-GC-TSD.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Gas; Humans; Lamotrigine; Phenobarbital; Phenytoin; Primidone; Triazines | 2002 |
Niguldipine impairs the protective activity of carbamazepine and phenobarbital in amygdala-kindled seizures in rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Amygdala; Animals; Anticonvulsants; Calcium Channel Agonists; Calcium Channel Blockers; Carbamazepine; Dihydropyridines; Drug Combinations; Injections, Intraperitoneal; Kindling, Neurologic; Male; Phenobarbital; Rats; Rats, Wistar; Seizures | 2002 |
Evaluation of fluorescence polarization assays for measuring valproic acid, phenytoin, carbamazepine and phenobarbital in serum.
Topics: Anticonvulsants; Automation; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Fluorescence Polarization; Humans; Phenobarbital; Phenytoin; Reproducibility of Results; Valproic Acid | 2002 |
Anticonvulsant hypersensitivity syndrome with marked eosinophilia in treatment of diabetic neuropathy.
Topics: Adult; Anticonvulsants; Carbamazepine; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Drug Hypersensitivity; Eosinophilia; Humans; Male; Phenobarbital; Phenytoin | 2002 |
Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Atenolol; Body Temperature; Carbamazepine; Epilepsy, Reflex; Female; Lamotrigine; Male; Metoprolol; Mice; Mice, Inbred DBA; Motor Activity; Phenobarbital; Propanolamines; Propranolol; Stereoisomerism; Triazines; Valproic Acid | 2002 |
Performance characteristics of four immunoassays for antiepileptic drugs on the IMMULITE 2000 automated analyzer.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Cross Reactions; Drug Monitoring; Humans; Immunoassay; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Uremia; Valproic Acid | 2002 |
Relationship between changes in drug score, D-glucaric acid excretion, and gamma-glutamyltransferase and beta-glucuronidase serum activities during anticonvulsant treatment.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Enzyme Induction; Epilepsy; Female; Follow-Up Studies; gamma-Glutamyltransferase; Glucaric Acid; Glucuronidase; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors | 2002 |
In vitro removal of therapeutic drugs with a novel adsorbent system.
Topics: Adsorption; Anti-Bacterial Agents; Biocompatible Materials; Carbamazepine; Digoxin; Glycopeptides; Hemoperfusion; Humans; Models, Biological; Phenobarbital; Phenytoin; Sorption Detoxification; Theophylline; Uremia; Valproic Acid | 2002 |
Effects of antiepileptic drugs on induced epileptiform activity in a rat model of dysplasia.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Anticonvulsants; Carbamazepine; Disease Models, Animal; Electroencephalography; Epilepsy; Ethosuximide; Female; Hippocampus; In Vitro Techniques; Lamotrigine; Methylazoxymethanol Acetate; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Triazines; Valproic Acid | 2002 |
Therapeutic drug monitoring of anticonvulsant drugs by micellar HPLC with direct injection of serum samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Micelles; Phenobarbital; Phenytoin | 2002 |
Intracerebroventricular injection of the antibiotic cefoselis produces convulsion in mice via inhibition of GABA receptors.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Bicuculline; Carbamazepine; Ceftizoxime; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; GABA Modulators; GABA-A Receptor Agonists; Injections, Intraventricular; Male; Mice; Mice, Inbred ICR; N-Methylaspartate; Phenobarbital; Phenytoin; Receptors, GABA; Seizures; Sodium Channel Blockers | 2002 |
SPECT in a patient with postictal PLEDs: is hyperperfusion evidence of electrical seizure?
Topics: Adult; Brain; Carbamazepine; Cerebrovascular Circulation; Electroencephalography; Epilepsies, Partial; Female; Humans; Hyperemia; Periodicity; Phenobarbital; Radiopharmaceuticals; Technetium Tc 99m Exametazime; Temporal Lobe; Tomography, Emission-Computed, Single-Photon | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
[Preparation and evaluation of wide-bore stainless-steel packed capillary liquid chromatographic columns].
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Phenobarbital; Stainless Steel; Theophylline | 2001 |
Evaluation of therapeutic drug monitoring of antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Hospitals, Teaching; Humans; Infant; Male; Middle Aged; Phenobarbital; Phenytoin; Polypharmacy; Valproic Acid | 2003 |
Effects of valproic acid, carbamazepine, and phenobarbitone on the fatty acid composition of erythrocyte membranes in children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Erythrocyte Membrane; Fatty Acids; Female; Humans; Infant; Male; Phenobarbital; Reference Values; Valproic Acid | 2003 |
A review of neurological disorders presenting at a paediatric neurology clinic and response to anticonvulsant therapy in Gambian children.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Developmental Disabilities; Female; Gambia; Humans; Infant; Learning Disabilities; Male; Nervous System Diseases; Phenobarbital; Phenytoin; Psychomotor Disorders; Seizures; Treatment Outcome | 2003 |
Serum carbamazepine concentrations in elderly patients: a case-matched pharmacokinetic evaluation based on therapeutic drug monitoring data.
Topics: Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Reference Values; Regression Analysis; Retrospective Studies | 2003 |
REPORT ON THE ANTI-EPILEPTIC ACTION OF TEGRETOL.
Topics: Acetazolamide; Adolescent; Anticonvulsants; Biomedical Research; Carbamazepine; Child; Chlordiazepoxide; Drug Therapy; Epilepsy; Epilepsy, Absence; Epilepsy, Temporal Lobe; Epilepsy, Tonic-Clonic; Humans; Hydantoins; Phenobarbital; Phenytoin; Primidone; Seizures; Temporal Lobe; Toxicology | 1964 |
Validated high performance liquid chromatographic method for simultaneous determination of phenytoin, phenobarbital and carbamazepine in human serum.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Reference Standards; Reproducibility of Results; Spectrophotometry, Ultraviolet | 2003 |
Cost of epilepsy in patients attending a secondary-level hospital in India.
Topics: Anticonvulsants; Carbamazepine; Efficiency, Organizational; Epilepsy; Hospital Costs; Hospitalization; Humans; India; Phenobarbital; Phenytoin; Valproic Acid | 2004 |
The effect of long-term antiepileptic treatment on serum cholesterol (TC, HDL, LDL) and triglyceride levels in adult epileptic patients on monotherapy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Triglycerides; Valproic Acid | 2004 |
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metabolic Clearance Rate; Methods; Models, Biological; Pharmacokinetics; Phenobarbital; Phenytoin; Regression Analysis; Valproic Acid | 2004 |
[Nonconvulsion epileptic encepholopathies and their treatment].
Topics: Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Humans; Magnetic Resonance Imaging; Male; Phenobarbital; Phenytoin; Severity of Illness Index; Tomography, X-Ray Computed | 2004 |
Activation of serum aminotransferases by pyridoxal-5' -phosphate in epileptic patients treated with anticonvulsant drugs.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Pyridoxal Phosphate; Sensitivity and Specificity; Transaminases; Valproic Acid | 2004 |
[Carbamazepine or phenobarbitone monotherapy in epilepsy?].
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Evidence-Based Medicine; Humans; Phenobarbital | 2004 |
[Anticonvulsant hypersensitivity syndrome].
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Drug Eruptions; Drug Hypersensitivity; Ethosuximide; Fever; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lymphatic Diseases; Phenobarbital; Phenytoin; Syndrome; Triazines; Valproic Acid | 2004 |
The study of growth inhibitive protein factor by various mode of HPLC and estimation of its binding with drugs.
Topics: Animals; Brain Chemistry; Carbamazepine; Chlorpromazine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Growth Inhibitors; Humans; Hydrophobic and Hydrophilic Interactions; Nerve Tissue Proteins; Phenobarbital; Protein Binding; Rats; Serum Albumin; Spectrophotometry, Ultraviolet | 2005 |
Assessment of the epilepsy treatment gap in two cities of south-east of Brazil.
Topics: Adult; Anticonvulsants; Brazil; Carbamazepine; Epilepsy; Health Services Accessibility; Health Services Needs and Demand; Humans; Phenobarbital; Phenytoin; Prevalence; Valproic Acid | 2004 |
Fracture risk associated with use of antiepileptic drugs.
Topics: Adult; Anticonvulsants; Bone Density; Carbamazepine; Case-Control Studies; Denmark; Epilepsy; Female; Fractures, Bone; Humans; Male; Middle Aged; Pharmacoepidemiology; Phenobarbital; Risk Factors; Valproic Acid | 2004 |
Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Riluzole; Seizures; Valproic Acid | 2004 |
Isoforms of serum gamma-glutamyltransferase in epileptic patients treated with enzyme-inducing anticonvulsant drugs.
Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; gamma-Glutamyltransferase; Humans; Isoenzymes; Male; Phenobarbital; Phenytoin | 2004 |
Influence of coadministered antiepileptic drugs on serum phenobarbital concentrations in epileptic patients: quantitative analysis based on a suitable transforming factor.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Combinations; Epilepsy; Female; Humans; Infant; Isoxazoles; Male; Middle Aged; Phenobarbital; Phenytoin; Sex Factors; Valproic Acid; Zonisamide | 2004 |
[Influence of psychotropic drugs on thrombocytes aggregation in patients with epilepsy].
Topics: Adolescent; Adult; Barbiturates; Carbamazepine; Epilepsy; Humans; In Vitro Techniques; Lamotrigine; Middle Aged; Phenobarbital; Phenytoin; Platelet Aggregation; Psychotropic Drugs; Thrombocytopenia; Triazines; Valproic Acid | 2004 |
Initiation of treatment and selection of antiepileptic drugs in childhood epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Epilepsy, Rolandic; Female; Follow-Up Studies; Humans; Infant; Male; Patient Care Planning; Phenobarbital; Practice Guidelines as Topic; Practice Patterns, Physicians'; Retrospective Studies; Valproic Acid | 2004 |
The correlation of deficits in IQ with midface and digit hypoplasia in children exposed in utero to anticonvulsant drugs.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Child; Cognition Disorders; Face; Facies; Female; Fingers; Follow-Up Studies; Humans; Intelligence Tests; Phenobarbital; Phenytoin; Pregnancy; Prenatal Exposure Delayed Effects; Risk Factors; Toes | 2005 |
Gingival enlargement in children treated with antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Case-Control Studies; Child; Cross-Sectional Studies; Dental Plaque Index; Epilepsy; Female; Gingival Overgrowth; Humans; Male; Periodontal Index; Phenobarbital; Risk Factors; Severity of Illness Index; Toothbrushing; Valproic Acid | 2004 |
Phenobarbital pharmacokinetics in old age: a case-matched evaluation based on therapeutic drug monitoring data.
Topics: Adult; Age Distribution; Age Factors; Aged; Aged, 80 and over; Aging; Algorithms; Anticonvulsants; Biological Availability; Carbamazepine; Drug Administration Schedule; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Regression Analysis | 2005 |
[Simultaneous analysis of theophylline, phenobarbital, amobarbital and carbamazepine in serum by high performance liquid chromatography].
Topics: Amobarbital; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Theophylline | 1997 |
Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis in new users of antiepileptics.
Topics: Anticonvulsants; Carbamazepine; Causality; Epilepsy; Germany; Humans; Incidence; Inpatients; Lamotrigine; Phenobarbital; Phenytoin; Prohibitins; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Stevens-Johnson Syndrome; Triazines; Valproic Acid | 2005 |
Simultaneous determination of lamotrigine, phenobarbitone, carbamazepine and phenytoin in human serum by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Reproducibility of Results; Sensitivity and Specificity; Triazines | 2005 |
The quantitative prediction of in vivo enzyme-induction caused by drug exposure from in vitro information on human hepatocytes.
Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Liver; Phenobarbital; Predictive Value of Tests; Rifampin | 2005 |
Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.
Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetamides; Animals; Anticonvulsants; Carbamazepine; Convulsants; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Female; In Vitro Techniques; Lacosamide; Male; Membrane Potentials; Patch-Clamp Techniques; Phenobarbital; Picrotoxin; Potassium Channel Blockers; Prohibitins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Visual Cortex | 2006 |
[Anticonvulsive pharmacotherapy may aggravate epilepsy course].
Topics: Anticonvulsants; Carbamazepine; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Fructose; Humans; Magnetic Resonance Imaging; Phenobarbital; Phenytoin; Topiramate; Valproic Acid | 2005 |
Mathematical representation of analyte's capacity factor in binary solvent mobile phases using the Jouyban-Acree model.
Topics: Algorithms; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Models, Chemical; Models, Statistical; Phenobarbital; Phenytoin; Solvents | 2005 |
2-phosphonomethyl-pentanedioic acid (glutamate carboxypeptidase II inhibitor) increases threshold for electroconvulsions and enhances the antiseizure action of valproate against maximal electroshock-induced seizures in mice.
Topics: Analysis of Variance; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Glutamate Carboxypeptidase II; Male; Mice; Organophosphorus Compounds; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2006 |
Correlation of retention factor of analytes in quaternary solvent mobile phases using the Jouyban-Acree model.
Topics: Algorithms; Carbamazepine; Models, Chemical; Models, Statistical; Phenobarbital; Phenytoin; Solvents | 2006 |
[Rapid analysis of antiepileptic drugs in human plasma by micellar electrokinetic capillary chromatography].
Topics: Anticonvulsants; Buffers; Carbamazepine; Chromatography, Micellar Electrokinetic Capillary; Clonazepam; Epilepsy; Humans; Hydrogen-Ion Concentration; Phenobarbital; Phenytoin; Primidone; Sensitivity and Specificity; Sodium Dodecyl Sulfate | 2006 |
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction.
Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones | 2006 |
Optimization of solid-phase microextraction procedures for the determination of tricyclic antidepressants and anticonvulsants in plasma samples by liquid chromatography.
Topics: Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricyclic; Carbamazepine; Chromatography, Liquid; Desipramine; Epoxy Compounds; Humans; Hydrogen-Ion Concentration; Imipramine; Lamotrigine; Nortriptyline; Phenobarbital; Phenylethylmalonamide; Polyurethanes; Primidone; Reproducibility of Results; Sensitivity and Specificity; Silanes; Time Factors; Triazines | 2006 |
Response to Zhou et al. Osteomalacia is a frequent complication resulting from long-term therapy with drugs such as phenytoin, carbamazepine, and phenobarbital.
Topics: Anticonvulsants; Carbamazepine; Constitutive Androstane Receptor; Gene Expression; Humans; Osteomalacia; Phenobarbital; Phenytoin; Pregnane X Receptor; Receptors, Calcitriol; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Steroid Hydroxylases; Transcription Factors; Vitamin D3 24-Hydroxylase | 2006 |
Antiepileptic TDM pattern at a tertiary care hospital in India.
Topics: Anticonvulsants; Carbamazepine; Drug Monitoring; Epilepsy; Humans; India; Pharmacology, Clinical; Pharmacy Service, Hospital; Phenobarbital; Phenytoin; Retrospective Studies | 2006 |
Serum lipid profile in children receiving anti-epileptic drug monotherapy: is it atherogenic?
Topics: Adolescent; Anticonvulsants; Apolipoproteins; Atherosclerosis; Carbamazepine; Child; Cholesterol, HDL; Epilepsy; Female; Humans; Lipids; Lipoproteins; Male; Phenobarbital; Valproic Acid | 2006 |
Taylor-type focal cortical dysplasia: is the epilepsy always resistant to medical treatment?
Topics: Adolescent; Anticonvulsants; Attention; Brain; Carbamazepine; Cerebral Cortex; Cognition; Epilepsies, Partial; Female; Humans; Magnetic Resonance Imaging; Memory; Phenobarbital; Psychomotor Performance; Radiography; Remission, Spontaneous; Seizures; Tomography, Emission-Computed, Single-Photon | 2006 |
The effects of carbamazepine, valproic acid and phenobarbital on the oxidative and antioxidative balance in epileptic children.
Topics: Anticonvulsants; Antioxidants; Bilirubin; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Lipid Peroxides; Male; Oxidative Stress; Peroxides; Phenobarbital; Serum Albumin; Uric Acid; Valproic Acid | 2007 |
Conventional anticonvulsant drugs in the guinea-pig kindling model of partial seizures: effects of repeated administration.
Topics: Action Potentials; Amygdala; Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Administration Schedule; Drug Evaluation, Preclinical; Electric Stimulation; Epilepsies, Partial; Ethosuximide; Female; Guinea Pigs; Kindling, Neurologic; Male; Phenobarbital; Phenytoin; Predictive Value of Tests; Reproducibility of Results; Species Specificity; Treatment Outcome; Valproic Acid | 2007 |
Unilateral multicystic dysplastic kidney in infants exposed to antiepileptic drugs during pregnancy.
Topics: Anticonvulsants; Carbamazepine; Epilepsy; Female; Follow-Up Studies; Humans; Infant, Newborn; Maternal-Fetal Exchange; Multicystic Dysplastic Kidney; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Prohibitins; Time Factors; Treatment Outcome; Ultrasonography, Prenatal | 2007 |
Evaluation of therapeutic drug level monitoring of phenobarbital, phenytoin and carbamazepine in Iranian epileptic patients.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Iran; Male; Middle Aged; Phenobarbital; Phenytoin | 2007 |
Effects of certain antiepileptics on behavioral and electromyographic seizure patterns induced by maximal electroshock in mice.
Topics: Administration, Oral; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electromyography; Electroshock; Ethosuximide; Fructose; Male; Mice; Phenobarbital; Phenytoin; Seizures; Time Factors; Topiramate | 2007 |
Chronically administered fluoxetine enhances the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Drug Synergism; Electroshock; Fluoxetine; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Selective Serotonin Reuptake Inhibitors; Valproic Acid | 2007 |
Interactions between two enantiomers of losigamone and conventional antiepileptic drugs in the mouse maximal electroshock model--an isobolographic analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Furans; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Stereoisomerism; Valproic Acid | 2007 |
Low serum concentrations of reboxetine in 2 patients treated with CYP3A4 inducers.
Topics: Adrenergic Uptake Inhibitors; Adult; Anticonvulsants; Bulimia Nervosa; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Antagonism; Enzyme Induction; Female; Humans; Male; Middle Aged; Morpholines; Phenobarbital; Reboxetine; Schizophrenia | 2007 |
Isobolographic analysis of interactions between remacemide and conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Acetamides; Algorithms; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Epilepsy; Epilepsy, Tonic-Clonic; Male; Memory; Mice; Motor Skills; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
Robust isocratic high performance liquid chromatographic method for simultaneous determination of seven antiepileptic drugs including lamotrigine, oxcarbazepine and zonisamide in serum after solid-phase extraction.
Topics: Analysis of Variance; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Drug Monitoring; Ethosuximide; Humans; Isoxazoles; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solid Phase Extraction; Solutions; Specimen Handling; Spectrophotometry, Ultraviolet; Temperature; Triazines; Valproic Acid; Zonisamide | 2007 |
Cholecalciferol enhances the anticonvulsant effect of conventional antiepileptic drugs in the mouse model of maximal electroshock.
Topics: Animals; Anticonvulsants; Avoidance Learning; Carbamazepine; Cholecalciferol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Injections, Intraperitoneal; Male; Mental Recall; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Vitamins | 2007 |
Acute and chronic treatment with mianserin differentially affects the anticonvulsant activity of conventional antiepileptic drugs in the mouse maximal electroshock model.
Topics: Analysis of Variance; Animals; Anticonvulsants; Antidepressive Agents, Second-Generation; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Electroshock; Fluorescent Antibody Technique; Male; Memory; Mianserin; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2007 |
[Evaluation of bone mineral density using digital image processing in children receiving anticonvulsants].
Topics: Absorptiometry, Photon; Adolescent; Age Determination by Skeleton; Anticonvulsants; Bone Density; Carbamazepine; Child; Child, Preschool; Female; Humans; Male; Phenobarbital; Valproic Acid | 2007 |
Prescribing patterns of antiepileptic drugs in Italy: a nationwide population-based study in the years 2000-2005.
Topics: Adolescent; Adult; Age Distribution; Aged; Amines; Anticonvulsants; Carbamazepine; Catchment Area, Health; Cohort Studies; Cyclohexanecarboxylic Acids; Drug Prescriptions; Drug Utilization; Epilepsy; Family Practice; Female; Gabapentin; gamma-Aminobutyric Acid; Geography; Humans; Italy; Longitudinal Studies; Male; Middle Aged; Mood Disorders; Pain; Pharmacoepidemiology; Phenobarbital; Practice Patterns, Physicians'; Prevalence; Valproic Acid | 2007 |
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil | 2008 |
Aromatic antiepileptic drugs and mitochondrial toxicity: effects on mitochondria isolated from rat liver.
Topics: Adenosine Triphosphate; Animals; Anticonvulsants; Calcium; Calcium Signaling; Carbamazepine; Dose-Response Relationship, Drug; Male; Membrane Potential, Mitochondrial; Microsomes, Liver; Mitochondria, Liver; Mitochondrial Swelling; Oxygen Consumption; Phenobarbital; Phenytoin; Rats; Rats, Wistar | 2008 |
Effect of 21-day exposure of phenobarbital, carbamazepine and phenytoin on P-glycoprotein expression and activity in the rat brain.
Topics: Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Carbamazepine; Gene Expression; Male; Phenobarbital; Phenytoin; Rats; Rats, Sprague-Dawley | 2008 |
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Sensitivity and Specificity | 2008 |
A study on epileptic negative myoclonus in atypical benign partial epilepsy of childhood.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Brain; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Myoclonic; Epilepsies, Partial; Female; Humans; Male; Oxcarbazepine; Phenobarbital; Seizures; Valproic Acid | 2009 |
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins.
Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency | 2008 |
Involvement of oxidative stress in the hepatotoxicity induced by aromatic antiepileptic drugs.
Topics: Animals; Anticonvulsants; Carbamazepine; Cardiolipins; Liver; Male; Malondialdehyde; Microsomes, Liver; Mitochondria, Liver; Oxidation-Reduction; Oxidative Stress; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Sulfhydryl Compounds; Toxicity Tests | 2008 |
Differential hippocampal pharmacokinetics of phenobarbital and carbamazepine in repetitive seizures induced by 3-mercaptopropionic acid.
Topics: 3-Mercaptopropionic Acid; Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Disease Models, Animal; Epilepsy; Hippocampus; Male; Microdialysis; Nimodipine; Phenobarbital; Rats; Rats, Wistar; Seizures; Time | 2009 |
Long-term antiepileptic drug administration during early life inhibits hippocampal neurogenesis in the developing brain.
Topics: Age Factors; Animals; Animals, Suckling; Anticonvulsants; Apoptosis; Brain Damage, Chronic; Carbamazepine; Cell Division; Clonazepam; Dentate Gyrus; DNA Replication; Doublecortin Protein; Fructose; Hippocampus; Neurogenesis; Neurons; Phenobarbital; Random Allocation; Rats; Rats, Sprague-Dawley; Topiramate; Valproic Acid | 2009 |
N-(anilinomethyl)-p-isopropoxyphenylsuccinimide potentiates the anticonvulsant action of phenobarbital and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Brain; Carbamazepine; Dose-Response Relationship, Drug; Drug Synergism; Male; Memory; Mice; Models, Animal; Motor Activity; Muscle Strength; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2009 |
Hyperhomocysteinemia in epileptic patients on new antiepileptic drugs.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Enzyme Induction; Epilepsy; Female; Folic Acid; Fructose; Genotype; Humans; Hyperhomocysteinemia; Lamotrigine; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Oxcarbazepine; Phenobarbital; Polymorphism, Genetic; Topiramate; Triazines; Vitamin B 12 | 2010 |
In vitro model for the prediction of clinical CYP3A4 induction using HepaRG cells.
Topics: Anticonvulsants; Biological Assay; Carbamazepine; Cell Line; Cytochrome P-450 CYP3A; Enzyme Induction; Enzyme Inhibitors; Hepatocytes; Humans; Phenobarbital; Rifampin | 2009 |
The effect of antiepileptic drugs on mitochondrial activity: a pilot study.
Topics: Adenosine Triphosphate; Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Electron Transport; Electron Transport Complex II; Electron Transport Complex III; Electron Transport Complex IV; Epilepsy; Humans; Lamotrigine; Leukocytes; Mitochondria; Oxidation-Reduction; Phenobarbital; Phosphorylation; Pilot Projects; Signal Transduction; Time Factors; Triazines | 2010 |
Absence of a general association between ABCB1 genetic variants and response to antiepileptic drugs in epilepsy patients.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Epilepsy; Female; Genotype; Humans; Male; Pharmacogenetics; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2010 |
Curcumin ameliorates cognitive dysfunction and oxidative damage in phenobarbitone and carbamazepine administered rats.
Topics: Animals; Anticonvulsants; Antioxidants; Avoidance Learning; Brain; Carbamazepine; Cognition Disorders; Curcumin; Drug Interactions; Lipid Peroxidation; Male; Malondialdehyde; Maze Learning; Memory Disorders; Oxidative Stress; Phenobarbital; Rats; Rats, Wistar | 2010 |
Benign infantile focal epilepsy with midline spikes and waves during sleep: a new epileptic syndrome or a variant of benign focal epilepsy?
Topics: Age of Onset; Anticonvulsants; Carbamazepine; Child, Preschool; Drug Therapy, Combination; Electroencephalography; Epilepsies, Partial; Female; Genetic Variation; Humans; Infant; Male; Phenobarbital; Seizures; Sleep; Syndrome; Valproic Acid | 2010 |
Effects of three N-(carboxyanilinomethyl) derivatives of p-isopropoxyphenylsuccinimide on the anticonvulsant action of carbamazepine, phenobarbital, phenytoin and valproate in the mouse maximal electroshock-induced seizure model.
Topics: Aniline Compounds; Animals; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Muscle Strength; Muscle, Skeletal; Phenobarbital; Phenytoin; Seizures; Succinimides; Valproic Acid | 2010 |
Cross-reactivity of skin rashes with current antiepileptic drugs in Chinese population.
Topics: Adolescent; Adult; Aged; Amines; Anticonvulsants; Carbamazepine; Chi-Square Distribution; Child; China; Clonazepam; Cyclohexanecarboxylic Acids; Exanthema; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Medicine, Chinese Traditional; Middle Aged; Phenobarbital; Phenytoin; Piracetam; Retrospective Studies; Topiramate; Triazines; Valproic Acid; Young Adult | 2010 |
Factors influencing valproate pharmacokinetics in children and adults.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Body Weight; Carbamazepine; Child; Child, Preschool; Drug Interactions; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Models, Biological; Phenobarbital; Serbia; Valproic Acid; Young Adult | 2010 |
Unilateral continuous subclinical paroxysmal activity: an unusual finding in a patient with recurrent absence status.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Diagnosis, Differential; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Fructose; Humans; Lamotrigine; Phenobarbital; Secondary Prevention; Status Epilepticus; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Weight Gain | 2010 |
Synthetic cannabinoid WIN 55,212-2 mesylate enhances the protective action of four classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzoxazines; Cannabinoid Receptor Agonists; Carbamazepine; Drug Synergism; Electroshock; Male; Memory, Long-Term; Mice; Morpholines; Muscle Strength; Naphthalenes; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Valproic Acid | 2011 |
Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs.
Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Midazolam; Nifedipine; Phenobarbital; Rifampin; Simvastatin; Substrate Specificity | 2011 |
One-way multiplexed immunoassay strategy for simultaneous determination of multi-analytes by microchip electrophoresis.
Topics: Antibodies, Immobilized; Carbamazepine; Electrophoresis, Microchip; Glass; Humans; Immunoassay; Phenobarbital; Phenytoin; Sodium Dodecyl Sulfate; Theophylline | 2011 |
Dupuytren's contracture as result of prolonged administration of phenobarbital.
Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Substitution; Dupuytren Contracture; Female; Humans; Male; Middle Aged; Orthopedic Procedures; Phenobarbital; Physical Therapy Modalities; Time Factors; Treatment Outcome | 2011 |
Thyroid status in a large cohort of patients with mental retardation: the TOP-R (Thyroid Origin of Psychomotor Retardation) study.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Cohort Studies; Cross-Sectional Studies; Drug Therapy, Combination; Female; Humans; Hyperthyroidism; Hypothyroidism; Intellectual Disability; Lamotrigine; Linear Models; Male; Middle Aged; Netherlands; Phenobarbital; Phenytoin; Prevalence; Thyroid Gland; Thyrotropin; Thyroxine; Triazines; Triiodothyronine; Valproic Acid | 2011 |
Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats.
Topics: Animals; Anticonvulsants; Carbamazepine; Curcumin; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Epilepsy; Male; Maze Learning; Phenobarbital; Phenytoin; Random Allocation; Rats; Rats, Wistar; Valproic Acid | 2011 |
Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Infant; Infant, Newborn; Lamotrigine; Male; Phenobarbital; Pregnancy; Prenatal Exposure Delayed Effects; Prevalence; Prospective Studies; Registries; Triazines; Valproic Acid | 2011 |
Factors influencing carbamazepine pharmacokinetics in children and adults: population pharmacokinetic analysis.
Topics: Adult; Aging; Anticonvulsants; Carbamazepine; Child; Chromatography, High Pressure Liquid; Drug Interactions; Epilepsy; Female; Half-Life; Humans; Male; Models, Statistical; Patient Compliance; Phenobarbital; Population; Reference Standards; Reproducibility of Results; Serbia; Spectrophotometry, Ultraviolet; Tablets | 2011 |
The antiepileptic drugs phenobarbital and carbamazepine reduce transport of methotrexate in rat choroid plexus by down-regulation of the reduced folate carrier.
Topics: Animals; Anticonvulsants; Biological Transport; Carbamazepine; Cell Line, Transformed; Choroid Plexus; Down-Regulation; Male; Methotrexate; Phenobarbital; Rats; Rats, Sprague-Dawley; Reduced Folate Carrier Protein | 2011 |
[Epilepsy in elderly].
Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Carbamazepine; Electroencephalography; Epilepsies, Partial; Epilepsy; Female; Fructose; Humans; Lamotrigine; Magnetic Resonance Imaging; Male; Middle Aged; Patient Compliance; Phenobarbital; Phenytoin; Topiramate; Triazines; Valproic Acid | 2011 |
Antiepleptic drug interactions: a clinical case demonstration.
Topics: Adolescent; Anticonvulsants; Brain; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Phenobarbital; Primidone; Valproic Acid | 2011 |
Novel micro-extraction by packed sorbent procedure for the liquid chromatographic analysis of antiepileptic drugs in human plasma and urine.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Humans; Oxcarbazepine; Phenobarbital; Phenytoin; Primidone; Prohibitins; Sensitivity and Specificity; Solid Phase Extraction; Spectrophotometry, Ultraviolet | 2012 |
Prevalence of seizures in children infected with human immunodeficiency virus.
Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Female; HIV Infections; Humans; Male; Phenobarbital; Prevalence; Retrospective Studies; Seizures; South Africa; Valproic Acid | 2013 |
How did phenobarbital's chemical structure affect the development of subsequent antiepileptic drugs (AEDs)?
Topics: Anticonvulsants; Carbamazepine; Drug Discovery; Epilepsy; Ethosuximide; History, 20th Century; Humans; Mephenytoin; Mephobarbital; Phenobarbital; Phenytoin; Primidone; Structure-Activity Relationship; Succinimides; Valproic Acid | 2012 |
Effect of pregabalin add-on treatment on seizure control, quality of life, and anxiety in patients with brain tumour-related epilepsy: a pilot study.
Topics: Adult; Aged; Anticonvulsants; Anxiety; Benzodiazepines; Brain Neoplasms; Carbamazepine; Clobazam; Drug Therapy, Combination; Epilepsy; Female; Fructose; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Pilot Projects; Piracetam; Pregabalin; Quality of Life; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Young Adult | 2012 |
[Patent rickets disclosed by loss of convulsion control in a boy with cerebral palsy].
Topics: Anticonvulsants; Calcium; Carbamazepine; Cerebral Palsy; Child, Preschool; Diazepam; Epilepsy; Humans; Hypocalcemia; Male; Microcephaly; Phenobarbital; Radiography; Rickets; Valproic Acid; Vitamin D; Vitamin D Deficiency | 2013 |
First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plas
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Drug Stability; Humans; Lamotrigine; Limit of Detection; Linear Models; Phenobarbital; Phenytoin; Reproducibility of Results; Triazines | 2013 |
Phenobarbital-induced severe cutaneous adverse drug reactions are associated with CYP2C19*2 in Thai children.
Topics: Adolescent; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Child; Child, Preschool; Cytochrome P-450 CYP2C19; DNA Mutational Analysis; Drug Hypersensitivity; Female; Genotype; HLA-B15 Antigen; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Polymorphism, Genetic; Skin; Thailand | 2013 |
Using CD40 ligand expression to detect antigen-specific T cells in patients with drug eruptions.
Topics: Aged; Anticonvulsants; Biomarkers; Carbamazepine; CD4-Positive T-Lymphocytes; CD40 Ligand; Cells, Cultured; Drug Eruptions; Humans; Lymphocyte Activation; Male; Phenobarbital | 2014 |
Osteomalacic myopathy: an uncommon side effect of antiepileptic drugs.
Topics: Anticonvulsants; Bone Density Conservation Agents; Carbamazepine; Cholecalciferol; Epilepsy; Humans; Male; Middle Aged; Muscular Diseases; Osteomalacia; Phenobarbital; Treatment Outcome | 2013 |
Sirenomelia after phenobarbital and carbamazepine therapy in pregnancy.
Topics: Abnormalities, Drug-Induced; Carbamazepine; Ectromelia; Epilepsy; Fatal Outcome; Female; Humans; Phenobarbital; Pregnancy | 2013 |
Seizure control and treatment changes in pregnancy: observations from the EURAP epilepsy pregnancy registry.
Topics: Anticonvulsants; Carbamazepine; Female; Humans; Lamotrigine; Phenobarbital; Pregnancy; Pregnancy Complications; Registries; Seizures; Treatment Outcome; Triazines; Valproic Acid | 2013 |
An examination of the mutual effects of valproic acid, carbamazepine, and phenobarbital on 25-hydroxyvitamin D levels and thyroid function tests.
Topics: Anticonvulsants; Carbamazepine; Child; Female; Humans; Hypothyroidism; Male; Phenobarbital; Thyroid Function Tests; Valproic Acid; Vitamin D | 2014 |
Anti-epileptic drugs inhibit viability of synoviocytes in vitro.
Topics: Animals; Anticonvulsants; Arthritis, Rheumatoid; Carbamazepine; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblasts; Histone Deacetylase Inhibitors; Humans; Phenobarbital; Phenytoin; Rabbits; Synovial Membrane; Valproic Acid | 2013 |
Effect of CYP3A5 genotypes on the pharmacokinetics of carbamazepine when used as monotherapy or co-administered with phenytoin, phenobarbital or valproic acid in Thai patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Asian People; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Female; Genotype; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2013 |
Antiepileptic drug utilization in Bangladesh: experience from Dhaka Medical College Hospital.
Topics: Adolescent; Adult; Anticonvulsants; Bangladesh; Carbamazepine; Child; Drug Combinations; Epilepsies, Partial; Epilepsy, Generalized; Female; Follow-Up Studies; Fructose; Hospitals, Teaching; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Retrospective Studies; Seizures; Topiramate; Treatment Outcome; Valproic Acid | 2013 |
Chemometrics enhanced HPLC-DAD performance for rapid quantification of carbamazepine and phenobarbital in human serum samples.
Topics: Anticonvulsants; Calibration; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Spectrophotometry, Ultraviolet | 2014 |
Epilepsy with myoclonic absences in siblings.
Topics: Anticonvulsants; Carbamazepine; Child; Developmental Disabilities; Electroencephalography; Epilepsies, Myoclonic; Family Health; Female; Follow-Up Studies; Humans; Male; Neuroimaging; Neuropsychological Tests; Phenobarbital; Siblings; Treatment Outcome | 2014 |
Association of HLA-B*1502 and *1511 allele with antiepileptic drug-induced Stevens-Johnson syndrome in central China.
Topics: Adolescent; Alleles; Anticonvulsants; Asian People; Carbamazepine; Child; Child, Preschool; China; Female; Genetic Predisposition to Disease; Genotype; HLA-B15 Antigen; Humans; Infant; Male; Oxcarbazepine; Phenobarbital; Polymerase Chain Reaction; Stevens-Johnson Syndrome | 2014 |
The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carbamazepine; Child; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Female; Forensic Toxicology; Humans; Hydrocortisone; Liver Cirrhosis; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Young Adult | 2014 |
Reboxetine and its influence on the action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Epilepsy; Male; Memory, Long-Term; Mice; Morpholines; Motor Activity; Phenobarbital; Phenytoin; Reboxetine; Valproic Acid | 2014 |
Interaction of famotidine, an H2 histamine receptor antagonist, with conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Drug Interactions; Electroshock; Famotidine; Histamine H2 Antagonists; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Psychomotor Performance; Valproic Acid | 2014 |
Liquid chromatographic assay based on microextraction by packed sorbent for therapeutic drug monitoring of carbamazepine, lamotrigine, oxcarbazepine, phenobarbital, phenytoin and the active metabolites carbamazepine-10,11-epoxide and licarbazepine.
Topics: Anticonvulsants; Carbamazepine; Chemical Fractionation; Chromatography, High Pressure Liquid; Chromatography, Liquid; Dibenzazepines; Drug Monitoring; Epoxy Compounds; Humans; Lamotrigine; Oxcarbazepine; Phenobarbital; Phenytoin; Quality Control; Reproducibility of Results; Triazines | 2014 |
Effect of status epilepticus and antiepileptic drugs on CYP2E1 brain expression.
Topics: Adolescent; Adult; Animals; Anticonvulsants; Brain; Carbamazepine; Cells, Cultured; Central Nervous System Depressants; Child, Preschool; Cytochrome P-450 CYP2E1; Disease Models, Animal; Endothelial Cells; Ethanol; Female; Humans; Infant; Male; Mice; Mice, Inbred C57BL; Middle Aged; Neurons; Phenobarbital; Phenytoin; Status Epilepticus | 2014 |
Nonlinear mixed effects modelling approach in investigating phenobarbital pharmacokinetic interactions in epileptic patients.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Lamotrigine; Male; Middle Aged; Models, Biological; Nonlinear Dynamics; Phenobarbital; Topiramate; Triazines; Valproic Acid | 2015 |
Inter-individual variation in the effect of antiepileptic drugs in the intrahippocampal kainate model of mesial temporal lobe epilepsy in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Diazepam; Disease Models, Animal; Drug Resistance; Electrodes, Implanted; Electroencephalography; Epilepsy, Temporal Lobe; Female; Hippocampus; Kainic Acid; Levetiracetam; Mice; Phenobarbital; Phenytoin; Piracetam; Seizures; Valproic Acid | 2015 |
Modafinil and its metabolites enhance the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock-induced seizure model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Benzhydryl Compounds; Brain; Carbamazepine; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Hand Strength; Male; Mice; Modafinil; Phenobarbital; Phenytoin; Psychomotor Performance; Seizures; Sulfones; Valproic Acid | 2015 |
Hyperammonemic encephalopathy after adjunction of phenobarbital to chronic topiramate and oxcarbazepine therapy.
Topics: Anticonvulsants; Brain Diseases; Carbamazepine; Child; Electroencephalography; Fructose; Humans; Hyperammonemia; Hypnotics and Sedatives; Male; Oxcarbazepine; Phenobarbital; Topiramate | 2015 |
Effect of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of classical antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Male; Methoxsalen; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2015 |
Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amines; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cyclohexanecarboxylic Acids; Databases, Factual; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Infant; Lamotrigine; Male; Middle Aged; Oxcarbazepine; Pharmacovigilance; Phenobarbital; Spain; Stevens-Johnson Syndrome; Triazines; Valproic Acid; Young Adult | 2015 |
Effects of CYP3A4/5 and ABCB1 genetic polymorphisms on carbamazepine metabolism and transport in Chinese patients with epilepsy treated with carbamazepine in monotherapy and bitherapy.
Topics: Adolescent; Adult; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; Carbamazepine; Child; China; Cytochrome P-450 Enzyme System; Drug Therapy, Combination; Epilepsy; Female; Genotype; Humans; Male; Middle Aged; Pharmacogenetics; Phenobarbital; Phenytoin; Polymorphism, Single Nucleotide; Valproic Acid; Young Adult | 2015 |
Concentration of antiepileptic drugs in persons with epilepsy: a comparative study in serum and saliva.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Prohibitins; Saliva; Young Adult | 2016 |
Mexiletine and its Interactions with Classical Antiepileptic Drugs: An Isobolographic Analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mexiletine; Mice; Motor Activity; Phenobarbital; Phenytoin; Seizures; Tissue Distribution; Valproic Acid | 2016 |
Propafenone enhances the anticonvulsant action of classical antiepileptic drugs in the mouse maximal electroshock model.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Male; Mice; Phenobarbital; Phenytoin; Propafenone; Valproic Acid | 2016 |
Factors influencing topiramate clearance in adult patients with epilepsy: A population pharmacokinetic analysis.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Epilepsy; Female; Fructose; Humans; Male; Middle Aged; Models, Biological; Oxcarbazepine; Phenobarbital; Phenytoin; Topiramate; Valproic Acid; Young Adult | 2016 |
Isobolographic Analysis of Interaction for Three-Drug Combination of Carbamazepine, Phenobarbital and Topiramate in the Mouse Maximal Electroshock-Induced Seizure Model.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Therapy, Combination; Electroshock; Fructose; Male; Mice; Phenobarbital; Seizures; Topiramate | 2016 |
The effects of cimetidine chronic treatment on conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Cimetidine; Drug Interactions; Electroshock; Male; Memory, Long-Term; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2016 |
Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model.
Topics: Administration, Oral; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Gastrointestinal Tract; Hepatocytes; Humans; Liver; Models, Biological; Phenobarbital; Phenytoin; Rifampin; RNA, Messenger | 2016 |
The effects of co-medications on lamotrigine clearance in Japanese children with epilepsy.
Topics: Adolescent; Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Child, Preschool; Clobazam; Clonazepam; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Infant, Newborn; Isoxazoles; Japan; Lamotrigine; Levetiracetam; Male; Phenobarbital; Phenytoin; Piracetam; Triazines; Valproic Acid; Young Adult; Zonisamide | 2016 |
Development, validation and clinical application of an online-SPE-LC-HRMS/MS for simultaneous quantification of phenobarbital, phenytoin, carbamazepine, and its active metabolite carbamazepine 10,11-epoxide.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |
Patterns of antiepileptic drugs use in epileptic pediatric patients in Jordan.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Cross-Sectional Studies; Drug Therapy, Combination; Epilepsy; Female; Fructose; Humans; Jordan; Levetiracetam; Male; Phenobarbital; Piracetam; Practice Patterns, Physicians'; Topiramate; Valproic Acid | 2016 |
Seizures triggered by pentylenetetrazol in marmosets made chronically epileptic with pilocarpine show greater refractoriness to treatment.
Topics: Animals; Anticonvulsants; Brain; Callithrix; Carbamazepine; Chronic Disease; Disease Models, Animal; Electrocorticography; Epilepsy; Female; Immunohistochemistry; Male; Neuropeptide Y; Pentylenetetrazole; Phenobarbital; Pilocarpine; Proto-Oncogene Proteins c-fos; Seizures; Valproic Acid | 2016 |
Vasculitis induced by phenobarbital with cross-reactivity to carbamazepine.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Drug Interactions; Female; Humans; Phenobarbital; Vasculitis, Leukocytoclastic, Cutaneous | 2017 |
[Therapeutic drug monitoring of three antiepileptic drugs - Back on twenty years of experience].
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Monitoring; Epilepsy; Humans; Medication Adherence; Morocco; Phenobarbital; Retrospective Studies; Valproic Acid | 2016 |
Characterization and application of restricted access carbon nanotubes in online extraction of anticonvulsant drugs from plasma samples followed by liquid chromatography analysis.
Topics: Adsorption; Animals; Anticonvulsants; Carbamazepine; Cattle; Chromatography, High Pressure Liquid; Equipment Design; Humans; Kinetics; Limit of Detection; Nanotubes, Carbon; Phenobarbital; Primidone; Prohibitins; Serum Albumin, Bovine | 2017 |
The capacity and effectiveness of diosmectite and charcoal in trapping the compounds causing the most frequent intoxications in acute medicine: A comparative study.
Topics: Adsorption; Alpha-Amanitin; Amlodipine; Antidotes; Aspirin; Carbamazepine; Charcoal; Digoxin; Ibuprofen; Imipramine; Oxazepam; Phenobarbital; Poisoning; Promethazine; Silicates; Theophylline | 2017 |
A survey of antiepileptic drug responses identifies drugs with potential efficacy for seizure control in Wolf-Hirschhorn syndrome.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clobazam; Female; Humans; Infant; Lamotrigine; Levetiracetam; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Quality of Life; Seizures; Topiramate; Wolf-Hirschhorn Syndrome; Young Adult | 2018 |
Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Biomarkers; Carbamazepine; Cytochrome P-450 CYP3A Inducers; Drug Monitoring; Enzyme Induction; Female; Humans; Hydroxycholesterols; Levetiracetam; Male; Middle Aged; Phenobarbital; Phenytoin; Retrospective Studies; Young Adult | 2018 |
Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.
Topics: Abnormalities, Drug-Induced; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Lamotrigine; Levetiracetam; Logistic Models; Male; Oxcarbazepine; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Topiramate; Valproic Acid; Young Adult | 2018 |
Psychiatric comedication in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Prospective Studies; Psychotropic Drugs; Triazines; Young Adult | 2018 |
Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.
Topics: Animals; Anticonvulsants; Antiparkinson Agents; Benzeneacetamides; Calcium Channel Blockers; Carbamazepine; Diazepam; Disease Models, Animal; Essential Tremor; Ethosuximide; Male; Mice, Inbred Strains; Nicotine; Phenobarbital; Propranolol; Pyridines; Valproic Acid | 2018 |
Frequency of drug combinations between enzyme-inducing first-generation antiepileptic drugs and inducible drugs in patients with epilepsy.
Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Italy; Male; Middle Aged; Phenobarbital; Phenytoin | 2018 |
Effects of androsterone on the protective action of various antiepileptic drugs against maximal electroshock-induced seizures in mice.
Topics: Androgens; Androsterone; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy; Gabapentin; Male; Mice; Phenobarbital; Psychomotor Performance; Seizures | 2019 |
Response to Carbamazepine in KCNQ2 Related Early Infantile Epileptic Encephalopathy.
Topics: Carbamazepine; Electroencephalography; Exons; Genetic Predisposition to Disease; Humans; KCNQ2 Potassium Channel; Phenobarbital; Potassium Channels, Voltage-Gated; Pyridoxine; Spasms, Infantile; Voltage-Gated Sodium Channels | 2019 |
Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice.
Topics: Animals; Anti-Arrhythmia Agents; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Disease Models, Animal; Dronedarone; Drug Interactions; Male; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
New derivative of 1,2,4-triazole-3-thione (TP427) potentiates the anticonvulsant action of valproate, but not that of carbamazepine, phenytoin or phenobarbital in the mouse tonic-clonic seizure model.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Male; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2019 |
Clinical profiles associated with serum perampanel concentrations in children with refractory epilepsy.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Dizziness; Drug Resistant Epilepsy; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Absence; Female; Humans; Infant; Male; Nitriles; Phenobarbital; Phenytoin; Pyridones; Retrospective Studies; Treatment Outcome | 2019 |
Etiology of neonatal seizures and maintenance therapy use: a 10-year retrospective study at Toulouse Children's hospital.
Topics: Anticonvulsants; Carbamazepine; Clonazepam; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Drug Administration Schedule; Electroencephalography; Epilepsy; Female; France; Hospitals, Pediatric; Hospitals, University; Humans; Infant, Newborn; Levetiracetam; Magnetic Resonance Imaging; Male; Phenobarbital; Piracetam; Prognosis; Retrospective Studies; Risk Assessment; Severity of Illness Index; Survival Rate; Term Birth; Time Factors; Treatment Outcome; Valproic Acid | 2019 |
Dried Blood Microsampling-Based Therapeutic Drug Monitoring of Antiepileptic Drugs in Children With Nodding Syndrome and Epilepsy in Uganda and the Democratic Republic of the Congo.
Topics: Anticonvulsants; Carbamazepine; Child; Chromatography, Liquid; Democratic Republic of the Congo; Dried Blood Spot Testing; Drug Monitoring; Epilepsy; Female; Hematocrit; Humans; Male; Nodding Syndrome; Onchocerciasis; Phenobarbital; Tandem Mass Spectrometry; Uganda; Valproic Acid | 2020 |
Nebivolol attenuates the anticonvulsant action of carbamazepine and phenobarbital against the maximal electroshock-induced seizures in mice.
Topics: Adrenergic beta-1 Receptor Agonists; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Female; Memory, Long-Term; Mice; Nebivolol; Phenobarbital; Seizures; Tissue Distribution | 2020 |
Influence of dose and antiepileptic comedication on brivaracetam serum concentrations in patients with epilepsy.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Child; Dibenzazepines; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Pyrrolidinones; Retrospective Studies; Young Adult | 2020 |
Effects of antiepileptic drugs on electroencephalography (EEG): Insights and applicability.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Electroencephalography; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Valproic Acid; Young Adult | 2020 |
Antiseizure drug efficacy and tolerability in established and novel drug discovery seizure models in outbred vs inbred mice.
Topics: Animals; Animals, Outbred Strains; Anticonvulsants; Behavior, Animal; Brain; Carbamazepine; Cornea; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Discovery; Drug Evaluation, Preclinical; Drug Resistant Epilepsy; Electroshock; Kindling, Neurologic; Lamotrigine; Levetiracetam; Locomotion; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Open Field Test; Phenobarbital; Seizures; Treatment Outcome; Valproic Acid | 2020 |
Effect of aliskiren on the anticonvulsant activity of antiepileptic drugs against 6 Hz-induced psychomotor seizures in mice.
Topics: Amides; Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Drug Interactions; Epilepsy, Temporal Lobe; Fumarates; Mice; Pentylenetetrazole; Phenobarbital; Seizures | 2020 |
Therapeutic Monitoring of Lacosamide in Japanese Patients With Epilepsy: Clinical Response, Tolerability, and Optimal Therapeutic Range.
Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Lacosamide; Male; Phenobarbital; Phenytoin; Sodium Channel Blockers | 2020 |
Pharmacokinetics, tolerability, and clinical effectiveness of perampanel in Japanese patients with epilepsy.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Child; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Japan; Male; Phenobarbital; Phenytoin; Seizures; Treatment Outcome | 2020 |
Anticonvulsant Effectiveness and Neurotoxicity Profile of 4-butyl-5-[(4-chloro-2-methylphenoxy)methyl]-2,4-dihydro-3H-1,2,4-triazole-3-thione (TPL-16) in Mice.
Topics: Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Male; Mice; Muscle Strength; Phenobarbital; Phenytoin; Rotarod Performance Test; Seizures; Thiones; Triazoles; Valproic Acid | 2021 |
Acute and chronic treatment with moclobemide, a reversible MAO-inhibitor, potentiates the antielectroshock activity of conventional antiepileptic drugs in mice.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Electroshock; Epilepsy; Female; Male; Memory, Long-Term; Mice; Moclobemide; Monoamine Oxidase Inhibitors; Motor Activity; Phenobarbital; Phenytoin; Seizures; Valproic Acid | 2021 |
Efficacy of phenobarbital in treating elderly epilepsy patients in rural northeast China: A community-based intervention trial.
Topics: Aged; Anticonvulsants; Carbamazepine; China; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Humans; Phenobarbital; Research Design; Rural Population | 2021 |
The Impact of Strong Inducers on Direct Oral Anticoagulant Levels.
Topics: Administration, Oral; Aged; Anticoagulants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Drug Monitoring; Female; Humans; Male; Phenobarbital; Phenytoin; Retrospective Studies; Rifampin | 2021 |
Chronic limbic epilepsy models for therapy discovery: Protocols to improve efficiency.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Epilepsy; Levetiracetam; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Rats; Seizures | 2021 |
Neuropsychological effects in children exposed to anticonvulsant monotherapy during gestation: Phenobarbital, carbamazepine, and phenytoin.
Topics: Anticonvulsants; Carbamazepine; Child; Female; Humans; Intelligence Tests; Phenobarbital; Phenytoin; Pregnancy | 2022 |
Study of the metabolic stability profiles of perampanel, rufinamide and stiripentol and prediction of drug interactions using HepaRG cells as an in vitro human model.
Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Dioxolanes; Drug Interactions; Humans; Nitriles; Phenobarbital; Pyridones; Rifampin; Triazoles | 2022 |
Trimetazidine, an Anti-Ischemic Drug, Reduces the Antielectroshock Effects of Certain First-Generation Antiepileptic Drugs.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Synergism; Electroshock; Epilepsy; Mice; Phenobarbital; Phenytoin; Trimetazidine; Valproic Acid | 2022 |
Serum folate levels in children with epilepsy seen in a tertiary health care facility in north central Nigeria.
Topics: Anticonvulsants; Carbamazepine; Child; Cross-Sectional Studies; Delivery of Health Care; Epilepsy; Folic Acid; Humans; Nigeria; Phenobarbital; Quality of Life; Valproic Acid | 2022 |
Ranolazine Interacts Antagonistically with Some Classical Antiepileptic Drugs-An Isobolographic Analysis.
Topics: Animals; Anticonvulsants; Avoidance Learning; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Epilepsy; Mice; Phenobarbital; Phenytoin; Ranolazine; Seizures | 2022 |
Interaction of Varenicline with Classic Antiseizure Medications in the Mouse Maximal Electroshock-Induced Seizure Model.
Topics: Animals; Anticonvulsants; Brain; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Varenicline | 2023 |
HLA alleles and antiseizure medication-induced cutaneous reactions in Brazil: A case-control study.
Topics: Alleles; Brazil; Carbamazepine; Case-Control Studies; HLA-A Antigens; HLA-B Antigens; Humans; Oxcarbazepine; Phenobarbital; Phenytoin | 2023 |
Simultaneous determination of 24 antiepileptic drugs and their active metabolites in human plasma by UHPLC-MS/MS.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Reproducibility of Results; Tandem Mass Spectrometry; Valproic Acid | 2023 |
The impact of a newly established specialized pediatric epilepsy center in Tanzania: An observational study.
Topics: Anticonvulsants; Benzodiazepines; Carbamazepine; Child; Epilepsy; Humans; Phenobarbital; Tanzania; Valproic Acid | 2023 |
Anticonvulsant effects of isopimpinellin and its interactions with classic antiseizure medications and borneol in the mouse tonic-clonic seizure model: an isobolographic transformation.
Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Electroshock; Humans; Mice; Phenobarbital; Phenytoin; Seizures | 2023 |