phenobarbital has been researched along with carbamazepine epoxide in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (43.33) | 18.7374 |
| 1990's | 14 (46.67) | 18.2507 |
| 2000's | 2 (6.67) | 29.6817 |
| 2010's | 1 (3.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosenmund, H; Wad, N | 1 |
| Lindhout, D; Meijer, JW; Meinardi, H; Nau, H | 1 |
| Breckenridge, AM; Guenthner, TM; Kitteringham, NR; Park, BK; Pirmohamed, M | 1 |
| Fazio, A; Martines, C; Pisani, F; Spina, E; Tomson, T; Trio, R | 1 |
| Briggle, TV; Guterman, A; McManus, DQ; Perchalski, R; Ramsay, RE; Vazquez, D; Wong, P; Yost, RA | 1 |
| Dimanico, U; Gianelli, M; Monaco, F; Mutani, R | 1 |
| Jürgens, U; May, T; Rambeck, B; Schnabel, R; Villagrán, R | 2 |
| Eadie, MJ; Herkes, GK; McKinnon, GE | 1 |
| Riad, LE; Sawchuk, RJ | 1 |
| Kaneniwa, N; Naito, H; Sumi, M; Umezawa, O; Watari, N | 1 |
| Asberg, A; Haffner, F | 1 |
| Berg, JD; Buckley, BM | 1 |
| Bonin, P; Casara, GL; Furlanut, M; Montanari, G | 1 |
| Albani, F; Ambrosetto, G; Baruzzi, A; Contin, M; Perucca, E; Procaccianti, G; Riva, R; Santucci, M | 1 |
| Neels, HM; Scharpé, SL; Totté, JA; Verkerk, RM; Vlietinck, AJ | 1 |
| Meijer, JW; Rambeck, B; Riedmann, M | 1 |
| Levy, RH; Patel, IH; Wedlund, PJ | 1 |
| Levy, RH; Patel, IH; Wedlund, P | 1 |
| Brown, RD; Rane, A; van Boxtel, CJ; Wilson, JT | 1 |
| Delgado, MR; Liu, H | 1 |
| Jones, SR; Ramachandran, S; Underhill, S | 1 |
| Camfield, CS; Camfield, PR; Dooley, JM; Fraser, AD; Gordon, KE | 1 |
| Abbott, FS; Bandiera, SM; Panesar, SK | 1 |
| Pippenger, CE; Svinarov, DA | 1 |
| Dutton, J; Higgins, G; Hughes, A; Roberts, NB | 1 |
| Jürgens, U; May, T; Rambeck, B; Schnabel, R | 1 |
| Jiao, Z; Shi, XJ; Zhao, ZG; Zhong, MK | 1 |
| Bertucci, C; Chaves, AR; Dreossi, SA; Malfará, WR; Queiroz, ME; Queiroz, RH; Valério, DA | 1 |
| Fan, Y; Ma, K; Qu, L; Wang, W; Yin, Z | 1 |
1 trial(s) available for phenobarbital and carbamazepine epoxide
| Article | Year |
|---|---|
Relationships between carbamazepine-diol, carbamazepine-epoxide, and carbamazepine total and free steady-state concentrations in epileptic patients: the influence of age, sex, and comedication.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Protein Binding; Sex Factors | 1996 |
29 other study(ies) available for phenobarbital and carbamazepine epoxide
| Article | Year |
|---|---|
Rapid quantitative method for the simultaneous determination of carbamazepine, carbamazepine-10,11-epoxide, diphenylhydantion, mephenytoin, phenobarbital and primidone in serum by thin-layer chromatography.
Topics: Carbamazepine; Chromatography, Thin Layer; Drug Combinations; Epoxy Compounds; Humans; Hydantoins; Mephenytoin; Phenobarbital; Phenytoin; Primidone | 1978 |
Antiepileptic drugs and teratogenesis in two consecutive cohorts: changes in prescription policy paralleled by changes in pattern of malformations.
Topics: Abnormalities, Drug-Induced; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Prescriptions; Epilepsy; Female; Humans; Infant; Infant, Newborn; Male; Phenobarbital; Phenytoin; Pregnancy; Pregnancy Complications; Valproic Acid | 1992 |
An investigation of the formation of cytotoxic, protein-reactive and stable metabolites from carbamazepine in vitro.
Topics: Animals; Ascorbic Acid; Biotransformation; Carbamazepine; Cell Death; Cytosol; Epoxide Hydrolases; Glutathione; Humans; Ketoconazole; Lymphocytes; Mice; Microsomes, Liver; Models, Chemical; Phenobarbital; Proteins | 1992 |
Effect of phenobarbital on the pharmacokinetics of carbamazepine-10,11-epoxide, an active metabolite of carbamazepine.
Topics: Adult; Biological Availability; Carbamazepine; Drug Interactions; Epilepsy; Humans; Male; Middle Aged; Phenobarbital | 1991 |
Carbamazepine metabolism in humans: effect of concurrent anticonvulsant therapy.
Topics: Administration, Oral; Adolescent; Adult; Carbamazepine; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Half-Life; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
A simple and disposable visual measuring device to assay antiepileptic drugs from whole blood samples.
Topics: Anticonvulsants; Carbamazepine; Chromatography; Humans; Immunoenzyme Techniques; Phenobarbital; Phenytoin | 1990 |
Postmortem serum protein binding and brain concentrations of antiepileptic drugs in autoptic specimens from 45 epileptic patients.
Topics: Anticonvulsants; Blood Proteins; Brain; Carbamazepine; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Protein Binding; Valproic Acid | 1990 |
Simultaneous quantitation of salivary carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbitone by high-performance liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin; Saliva; Spectrophotometry, Ultraviolet | 1989 |
Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography.
Topics: Adult; Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Male; Phenobarbital; Phenytoin; Quality Control; Statistics as Topic; Therapeutic Equivalency | 1988 |
[Influence of phenobarbital on pharmacokinetics of carbamazepine and its epoxide metabolite in the rabbit].
Topics: Animals; Carbamazepine; Male; Models, Biological; Phenobarbital; Rabbits | 1987 |
Analysis of serum concentration of phenobarbital, phenytoin, carbamazepine and carbamazepine 10,11-epoxide by solvent-recycled liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Phenobarbital; Phenytoin | 1987 |
Rapid measurement of anticonvulsant drug concentrations in the out-patient clinic, using HPLC with direct injection of plasma.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Evaluation Studies as Topic; Humans; Phenobarbital; Phenytoin | 1987 |
Carbamazepine and carbamazepine-10,11-epoxide serum concentrations in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Ethosuximide; Female; Humans; Infant; Kinetics; Male; Phenobarbital; Phenytoin; Primidone; Sex Factors | 1985 |
Lateral gaze nystagmus in carbamazepine-treated epileptic patients: correlation with total and free plasma concentrations of parent drug and its 10,11-epoxide metabolite.
Topics: Adult; Carbamazepine; Epilepsy; Female; Humans; Male; Nystagmus, Pathologic; Phenobarbital | 1985 |
Simultaneous high performance liquid-chromatographic determination of carbamazepine, carbamazepine-10,11-epoxide, ethosuximide, phenobarbital, phenytoin, primidone and phenylethylmalonamide in plasma.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone | 1983 |
Quantitative simultaneous determination of eight common antiepileptic drugs and metabolites by liquid chromatography.
Topics: Anticonvulsants; Carbamazepine; Chromatography, Liquid; Ethosuximide; Humans; Phenobarbital; Phenylethylmalonamide; Phenytoin; Primidone; Succinimides | 1981 |
Induction effect of phenobarbital on carbamazepine-10,11-epoxide kinetics in the rhesus monkey.
Topics: Animals; Biotransformation; Carbamazepine; Kinetics; Macaca mulatta; Male; Phenobarbital | 1982 |
Induction effect of phenobarbital on the carbamazepine to carbamazepine-10, 11-epoxide pathway in rhesus monkeys.
Topics: Animals; Carbamazepine; Drug Interactions; Enzyme Induction; Glucaric Acid; Kinetics; Macaca mulatta; Models, Biological; Phenobarbital; Time Factors | 1981 |
The formation of carbamazepine epoxide by rat liver microsomes: an investigation of the biphasic kinetic profile.
Topics: Aging; Animals; Carbamazepine; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1981 |
Interactions of phenobarbital and phenytoin with carbamazepine and its metabolites' concentrations, concentration ratios, and level/dose ratios in epileptic children.
Topics: Biotransformation; Carbamazepine; Child; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Male; Oxidoreductases; Phenobarbital; Phenytoin | 1995 |
Measurement of lamotrigine under conditions measuring phenobarbitone, phenytoin, and carbamazepine using reversed-phase high-performance liquid chromatography at dual wavelengths.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Lamotrigine; Phenobarbital; Phenytoin; Spectrophotometry, Ultraviolet; Triazines | 1994 |
The use of antiepileptic drug levels in children: a survey of Canadian pediatric neurologists.
Topics: Adolescent; Anticonvulsants; Attitude of Health Personnel; Carbamazepine; Child; Epilepsy; Ethosuximide; Female; Humans; Male; Phenobarbital; Valproic Acid | 1993 |
Postmortem concentrations of phenobarbital, carbamazepine, and its metabolite carbamazepine-10,11-epoxide in different regions of the brain and in the serum: analysis of autoptic specimens from 51 epileptic patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autopsy; Brain Chemistry; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Tissue Distribution | 1993 |
Comparative effects of carbamazepine and carbamazepine-10,11-epoxide on hepatic cytochromes P450 in the rat.
Topics: Animals; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Male; Microsomes, Liver; Phenobarbital; Rats; Steroid Hydroxylases | 1996 |
The incorporation of lamotrigine into the routine automated sequential trace enrichment of dialysates assay of anticonvulsants.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Lamotrigine; Phenobarbital; Phenytoin; Triazines | 1998 |
Comparison between premortem and postmortem serum concentrations of phenobarbital, phenytoin, carbamazepine and its 10,11-epoxide metabolite in institutionalized patients with epilepsy.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Carbamazepine; Epilepsy; Female; Hospitalization; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Postmortem Changes; Time Factors | 1999 |
Population pharmacokinetic modeling of steady state clearance of carbamazepine and its epoxide metabolite from sparse routine clinical data.
Topics: Administration, Oral; Adolescent; Adult; Anticonvulsants; Asian People; Body Weight; Carbamazepine; Chromatography, High Pressure Liquid; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Metabolic Clearance Rate; Methods; Models, Biological; Pharmacokinetics; Phenobarbital; Phenytoin; Regression Analysis; Valproic Acid | 2004 |
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Humans; Phenobarbital; Phenytoin; Sensitivity and Specificity | 2008 |
Development, validation and clinical application of an online-SPE-LC-HRMS/MS for simultaneous quantification of phenobarbital, phenytoin, carbamazepine, and its active metabolite carbamazepine 10,11-epoxide.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Female; Humans; Male; Phenobarbital; Phenytoin; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2016 |