phenobarbital and caffeine

phenobarbital has been researched along with caffeine in 187 studies

Research

Studies (187)

TimeframeStudies, this research(%)All Research%
pre-1990129 (68.98)18.7374
1990's19 (10.16)18.2507
2000's22 (11.76)29.6817
2010's14 (7.49)24.3611
2020's3 (1.60)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Carrupt, PA; Martel, S; Ottaviani, G2
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Sen, S; Sinha, N1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A1
Asai, S; Kubodera, T; Nadai, T; Tatematsu, A; Yoshizumi, H1
File, SE; Hyde, JR1
Hanson, HM; Ivester, CA; Morton, BR1
Pasricha, JS1
Adamkov, J; Bevilaqua, L; Drobný, M; Fundárek, J; Knéslová, L; Pithová, B; Wolfová, E1
Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE1
DeAngelis, RL; Hsu, SY; Welch, RM1
Abakumova, OIu; Kutsenko, NG; Lerman, MI; Podobed, OV1
Gan, IE; Schier, GM1
Boone, DL; Copeland, RF; Duggans, CF; Floyd-Jones, T; Kuo, WN; Smith, SO; Williams, JL1
Gourevitch, A; Yanev, S1
Pleshkova, NM; Shestakov, VV; Shutov, AA1
Bennett, EL; Flood, JF; Jarvik, ME; Orme, AE; Rosenzweig, MR1
Kaneko, M; Kaneko, Y; Kumashiro, H; Takahashi, Y1
Jenssen, D; Ramel, C1
Lefkowitz, SS; Nemeth, D1
Cravey, RH; Turner, JE1
Panikarskiĭ, VG1
Aldridge, A; Neims, AH; Parsons, WD1
Pozdniakov, VS1
Butler, CM; Hill, RM; Horning, MG; Howlin, J1
Aeschbacher, HU; Atkinson, J; Domahidy, B1
Borisenko, SA; Burov, IuV1
Butler, CM; Hill, RM; Horning, MG; Lertratanangkoon, K; Nowlin, J; Sommer, K1
Aeschbacher, HU1
Waldeck, B1
Hill, RM; Horning, MG; Sommer, KR1
Chiang, CY; Lefkowitz, SS1
Johnson, GF; Least, CJ; Solomon, HM1
Autret, E; Laugier, J; Nasr, C; Saliba, E; Suc, AL1
Ishikawa, A; Kobayashi, S; Misawa, S; Tanaka, E; Uchida, E; Yamamoto, Y; Yasuhara, H1
Billion-Rey, F; Brazier, JL; Guilluy, R1
Shestakov, VV; Shutov, AA1
Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H1
Hasegawa, T1
Gong, HL; Wang, GF; Wu, YT1
Berthou, F; Dreano, Y; Guillouzo, A; Mondine, P; Ratanasavanh, D; Riche, C1
Kalhorn, TF; Lee, CA; Nelson, SD; Slattery, JT1
Dĕdic, K; Horácek, J1
Baty, C; Jambou, J; Leducq, B; Richard, L1
al-Chalabi, KA; al-Khayat, B; Ziz, LA1
Clerc, JT; Kosmeas, N1
Gomez, J; Rodriguez, A1
Devenyi, P; Rideout, J; Schneiderman, J1
Budka, I; Fikr, V; Stika, L1
Wu, Q; Yang, JY1
Brazier, JL; Cherrah, Y; Desage, M; Falconnet, JB; Tillement, JP; Zini, R1
Govindwar, SP; Kachole, MS; Pawar, SS1
Bauer, M; Bauerová, J; Bojar, Z; Dobrotka, G; Marsinová, G1
Broly, F; Carpentier, C; Houdret, N; Lequien, P; Lhermitte, M; Roussel, P; Zaoui, C1
Abbruzzi, R; Bastone, A; Bianchi, M; Bonati, M; Catalani, P; Guaitani, A; Latini, R; Pantarotto, C; Szczawinska, K1
Ortweiler, W; Peiker, G; Siegert, C; Splinter, FK; Traeger, A1
Kusenbach, G; Reinhardt, D1
Mendez-Alvarez, E; Sierra-Marcuño, G; Soto-Otero, R1
Benkö, A1
Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ1
Giurgea, CE; Moyersoons, FE1
Beyrich, T; Schleuder, M1
Koch, H1
Frank, GB; Jhamandas, K1
Lombrozo, L; Mitoma, C1
Izquierdo, I1
Falk, M; Fürst, W1
Smith, RL; Timbrell, JA1
Riethe, P; Wilske, E1
Doenicke, A; Konrad, T; Kugler, J; Laub, M; Wittmann, R1
Mancuso, G; Priolisi, A; Ziino, L1
Monnat, A1
Cornish, HH; Khanna, KL1
Hill, RM; Horning, MG; Lertratanangkoon, K; Nowlin, J; Stillwell, RN; Stillwell, WG1
Kammerl, E; Schlemmer, W1
Harvey, DJ; Hill, RM; Horning, MG; Nowlin, HJ; Stillwell, WG1
Panchenko, EN1
Basu, TK; Bishun, NP; Raven, RW; Williams, DC1
Cassell, WA; Hemingway, P1
Morikawa, M1
Boucher, EA; Horning, EC; Horning, MG; Stafford, M1
Kato, Y; Ouchi, T1
Marcus, RJ; Roberts, E; Simonsen, DG; Winters, WD1
Paschke, M; Schwanitz, F1
Hansch, C; Martin, YC1
Filipescu, A; Spirescu, J1
Rupollo, W2
Bapat, SK; Dhawn, BN; Saxena, VC1
Morrison, CF; Stephenson, JA1
Dehn, F; LeValley, SE; Lombrozo, L; Mitoma, C1
Eich, E; Geissler, H; Mutschler, E; Schunack, W1
Kiper, EM1
Breunig, HL; Broadlick, DE; Comer, JP; Sampson, CB1
Hess, R1
Gleiss, J1
Preibisch-Effenberger, R; Schmidt, V1
Burba, JV1
Burgison, RM; Dietz, AJ1
Barnett, HJ; Richards, RN1
Guillory, JK; Hwang, SC; Lach, JL1
Knothe, J; Preibischèffenberger, R1
Novotný, I; Vyskocil, F1
Wojnarowska, W1
Navrátil, K1
Blake, MI; Lin, SL1
Harrison, A; Neyraut-Sutterman, MT1
Anderson, SM; Daly, JW; Padgett, W; Weir, RL1
Drobný, M; Fundárek, J; Knéslová, L; Pithová, B1
Bukowskyj, M; Munt, PW; Nakatsu, K1
Chung, LW; Simpson, VJ1
Perlík, F1
Todorov, S1
Emley, GS; Hutchinson, RR1
Chessebeuf, M; Exilie-Frigere, MF; Padieu, P; Wood, G1
Arnaud, MJ; Bircher, J; Preisig, R; Voegelin, M; Wietholtz, H1
Hirshkowitz, M; Karacan, I; Thornby, JI1
Chaput de Saintonge, DM; Hong, CY; Turner, P1
Maier-Lenz, H; Ringwelski, L; Windorfer, A1
Angioi, RM; Bonetti, EP; Cumin, R; Haefely, WE; Möhler, H; Pieri, L; Polc, P1
Brazier, JL; Desage, M; Renaud, H; Ribon, B; Salle, B1
Czok, G; Finke, A1
Czok, G1
Bracken, W; Bullock, P; Draper, A; Parkinson, A; Pearce, R; Podval, J; Thomas, P; Veltman, J1
Balansky, RM; Blagoeva, PM; De Flora, S; Mircheva, ZI1
Kaa, E1
Jaw, S; Jeffery, EH1
Borowicz, K; Buszewicz, G; Czuczwar, SJ; Gasior, M; Kleinrok, Z1
Batzias, J; Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM1
Shapovalov, VV; Shapovalova, VO1
Fujita, S; Funae, Y; Imaoka, S; Kazusaka, A; Maeda, Y; Masuda, M; Morita, K1
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM1
Chakrabarti, SK; Karas, M1
De Vivo, DC; Fischbarg, J; Ho, YY; Klepper, J; Wang, D; Yang, H1
Burgos, JS; Frizzo, ME; Lara, DR; Ramírez, G; Schmidt, AP; Souza, DO1
Agbaba, D; Aleksic, M; Eric, S; Franeta, JT; Pavkov, S; Vladimirov, S1
Fang, HH; Wen, L1
Gordon, N; Newton, RW1
HIGUCHI, T; LACH, JL1
LUSTIG, B1
BABES, A; PARHON, CI; PETREA, I1
LOLOVA, Kh; STOIMENOV, I1
AVRAMOV, NR1
ULMER, F1
SARSUNOVA, M; SCHWARZ, V1
SERVERDUPUY, JM1
EYSOLD, R1
WINBERG, J1
POPEK, K1
SENNE, W1
REMEZOVA, ES; SAFONOVA, SA1
MONCKTON, G1
BESSIN, P; BOISSIER, JR; DUMONT, C1
TEUCHMANN, JK; WIGLUSZ, Z1
WANSEL, H1
GOLDSTEIN, L; MURPHREE, HB; PFEIFFER, CC; SUGERMAN, AA1
Kuribara, H; Maruyama, Y; Weintraub, ST; Yoshihama, T1
KRISCHEK, J1
Guy, RH; Kalia, YN; Sekkat, N1
Batterham, P; Chung, H; Daborn, PJ; Lumb, C; Robin, C; Willoughby, L1
Błaszczyk, B; Chrościńska-Krawczyk, M; Czuczwar, SJ; Jankiewicz, K1
Ganguly, R; Kuruganti, S; Lam, V; Lucchesi, JC; Morra, R1
Bankstahl, JP; Bankstahl, M; Bloms-Funke, P; Löscher, W1
Gaburjakova, J; Gaburjakova, M1
Bendix, I; Bührer, C; Endesfelder, S; Schiller, C; Sifringer, M; Weichelt, U1
Bührer, C; Endesfelder, S; Schiller, C; von Haefen, C; Weichelt, U; Winter, K1
Ahmed, W; Biswas, NR; Halder, N; Menon, V; Saxena, R; Velpandian, T; Vijayakumar, AR1
Araújo, DB; Azevedo, JEC; Barbas, LAL; da Silva, ALM; Hamoy, AO; Hamoy, M; Lopes, DCF; Lopez, MEC; Mello, VJ; Nascimento, CP; Pereira, RG; Rodrigues, SF; Vieira, LR1
Anilanmert, B; Caglar-Andac, S; Narin, I1

Reviews

5 review(s) available for phenobarbital and caffeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug metabolism in the human neonate.
    Life sciences, 1975, Mar-01, Volume: 16, Issue:5

    Topics: Adult; Animals; Barbiturates; Caffeine; Epoxy Compounds; Female; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Maternal-Fetal Exchange; Meperidine; Milk; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Placenta; Pregnancy; Time Factors

1975
Theophylline reassessed.
    Annals of internal medicine, 1984, Volume: 101, Issue:1

    Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; Caffeine; Contraceptives, Oral; Cooking; Cystic Fibrosis; Drug Interactions; Erythromycin; Female; Heart Diseases; Histamine H2 Antagonists; Humans; Hypoxia; Infections; Kinetics; Liver Diseases; Lung Diseases, Obstructive; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Respiration Disorders; Sleep; Smoking; Theophylline

1984
Glucose transporter type1 (GLUT-1) deficiency.
    Brain & development, 2003, Volume: 25, Issue:7

    Topics: Anticonvulsants; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Caffeine; Central Nervous System Stimulants; Chromosomes, Human, Pair 1; Glucose; Glucose Transporter Type 1; Humans; Ketosis; Learning Disabilities; Monosaccharide Transport Proteins; Mutation; Phenobarbital; Seizures; Thioctic Acid

2003
[Caffeine and antiepileptic drugs: experimental and clinical data].
    Przeglad lekarski, 2007, Volume: 64, Issue:11

    Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid

2007

Trials

6 trial(s) available for phenobarbital and caffeine

ArticleYear
[Effectiveness of fenalgin SPOFA in lumboischiadic syndrome (author's transl)].
    Bratislavske lekarske listy, 1979, Volume: 71, Issue:4

    Topics: Acetaminophen; Adult; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Middle Aged; Phenobarbital; Sciatica; Syndrome

1979
[Analgetic effects on the stimulus threshold of the human tooth].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Administration, Oral; Amides; Analgesics; Analysis of Variance; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Differential Threshold; Drug Evaluation; Electric Stimulation; Fumarates; Humans; Pain; Phenacetin; Phenobarbital; Piperidines; Placebos; Propionates; Pyridines; Toothache

1974
[Electroencephalographic determination of vigilance following DL-propiramfumarate].
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:4

    Topics: Amides; Analgesics; Aspirin; Attention; Caffeine; Clinical Trials as Topic; Codeine; Drug Synergism; Electroencephalography; Electrooculography; Ethanol; Eye Movements; Female; Fumarates; Humans; Male; Phenacetin; Phenobarbital; Piperidines; Placebos; Promethazine; Propionates; Pyridines

1974
Effect of four centrally acting drugs on handwriting.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Caffeine; Chlorpromazine; Female; Handwriting; Humans; Male; Methamphetamine; Phenobarbital; Placebos

1969
[DP-Neuralgen. Clinical trials in patients with the radicular syndrome].
    Casopis lekaru ceskych, 1983, Jan-21, Volume: 122, Issue:3

    Topics: Adult; Analgesics; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Phenacetin; Phenobarbital

1983
[Clinical evaluation of analgesics].
    Casopis lekaru ceskych, 1984, Jan-20, Volume: 123, Issue:3

    Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain; Phenobarbital

1984

Other Studies

176 other study(ies) available for phenobarbital and caffeine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
    Journal of medicinal chemistry, 2006, Jun-29, Volume: 49, Issue:13

    Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water

2006
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
    Journal of medicinal chemistry, 2007, Feb-22, Volume: 50, Issue:4

    Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water

2007
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
    Bioorganic & medicinal chemistry letters, 2021, 10-01, Volume: 49

    Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines

2021
Mass spectrometry of medicines. Quantitative determination by direct probe inlet system mass chromatography.
    Biomedical mass spectrometry, 1978, Volume: 5, Issue:3

    Topics: Aspirin; Barbital; Barbiturates; Caffeine; Mass Spectrometry; Pharmaceutical Preparations; Phenacetin; Phenobarbital; Phenytoin

1978
A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 11, Issue:1

    Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Central Nervous System Stimulants; Flurazepam; Humans; Interpersonal Relations; Meprobamate; Motor Activity; Phenobarbital; Rats; Social Behavior

1979
Nicotine self-administration in rats.
    NIDA research monograph, 1979, Issue:23

    Topics: Amphetamine; Animals; Caffeine; Chlordiazepoxide; Chlorpromazine; Drug Interactions; Drug Tolerance; Ethanol; Humans; Male; Mecamylamine; Nicotine; Pentolinium Tartrate; Phenobarbital; Phenytoin; Rats; Reinforcement, Psychology; Self Administration; Substance-Related Disorders

1979
Drugs causing fixed eruptions.
    The British journal of dermatology, 1979, Volume: 100, Issue:2

    Topics: Antipyrine; Caffeine; Cross Reactions; Drug Combinations; Drug Eruptions; Humans; Penicillin G; Phenacetin; Phenobarbital; Pyridones; Sulfadiazine; Sulfanilamides; Tetracycline

1979
Use of saliva in therapeutic drug monitoring.
    Clinical chemistry, 1977, Volume: 23, Issue:2 PT. 1

    Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline

1977
Effect of Aroclor 1254, phenobarbital, and polycyclic aromatic hydrocarbons on the plasma clearance of caffeine in the rat.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:5 Pt 2

    Topics: Animals; Aroclors; Caffeine; Chromatography, Thin Layer; Drug Interactions; Enzyme Induction; Liver; Male; Metabolic Clearance Rate; Phenobarbital; Polychlorinated Biphenyls; Polycyclic Compounds; Rats

1977
[Accelerated microsomal DNA synthesis under the influence of xenobiotics and chemical carcinogens].
    Biokhimiia (Moscow, Russia), 1979, Volume: 44, Issue:4

    Topics: Animals; Benzopyrenes; Caffeine; Cell Nucleus; Cycloheximide; DNA; DNA, Mitochondrial; DNA, Neoplasm; Hydroxyurea; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Puromycin; Stimulation, Chemical

1979
Interference of theophylline and caffeine in the gas-chromatographic estimation of phenobarbital.
    Clinical chemistry, 1979, Volume: 25, Issue:6

    Topics: Caffeine; Chromatography, Gas; Humans; Phenobarbital; Theophylline

1979
Changes in the activities of protein kinase modulators in the cerebellum of mice due to ethanol, caffeine, or phenobarbital administration.
    Experientia, 1979, Aug-15, Volume: 35, Issue:8

    Topics: Animals; Ascorbic Acid; Caffeine; Cerebellum; Enzyme Activation; Ethanol; Kinetics; Mice; Nerve Tissue Proteins; Phenobarbital; Protein Kinases

1979
Motor estimation of short time intervals under the effect of some psychotropic drugs.
    Acta physiologica et pharmacologica Bulgarica, 1979, Volume: 5, Issue:1

    Topics: Adult; Amphetamine; Caffeine; Chlorpromazine; Diazepam; Humans; Phenobarbital; Psychotropic Drugs; Reaction Time; Task Performance and Analysis; Time Perception

1979
[Disorders of cerebral hemodynamics and their correction in epilepsy].
    Sovetskaia meditsina, 1979, Issue:7

    Topics: Brain Ischemia; Caffeine; Cerebrovascular Circulation; Epilepsy; Humans; Papaverine; Phenobarbital

1979
Memory: modification of anisomycin-induced amnesia by stimulants and depressants.
    Science (New York, N.Y.), 1978, Jan-20, Volume: 199, Issue:4326

    Topics: Animals; Anisomycin; Avoidance Learning; Brain; Caffeine; Chloral Hydrate; Drug Interactions; Male; Memory; Mice; Nerve Tissue Proteins; Nicotine; Phenobarbital; Pyrrolidines

1978
Therapeutic usefulness of ergotamine tartrate for narcolepsy.
    The American journal of psychiatry, 1978, Volume: 135, Issue:7

    Topics: Adult; Caffeine; Drug Combinations; Ergotamine; Humans; Male; Narcolepsy; Phenobarbital

1978
Factors affecting the induction of micronuclei at low doses of X-rays, MMS and dimethylnitrosamine in mouse erythroblasts.
    Mutation research, 1978, Volume: 58, Issue:1

    Topics: Animals; Caffeine; Cell Cycle; Cell Nucleus; Chromosome Aberrations; Dimethylnitrosamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Erythroblasts; Erythrocytes; Male; Methyl Methanesulfonate; Mice; Mice, Inbred CBA; Mutagens; Phenobarbital; X-Rays

1978
Immunosuppression of rosette-forming cells.
    Advances in experimental medicine and biology, 1976, Volume: 73 Pt B

    Topics: Amphetamine; Animals; Body Weight; Caffeine; Erythrocytes; Humans; Immunity; Immunologic Techniques; Immunosuppression Therapy; Leukocytes; Male; Methadone; Mice; Morphine; Organ Size; Pentobarbital; Phenobarbital; Sheep; Spleen; Substance-Related Disorders

1976
A fatal ingestion of caffeine.
    Clinical toxicology, 1977, Volume: 10, Issue:3

    Topics: Adult; Autopsy; Caffeine; Female; Humans; Phenobarbital

1977
[Problems in treatment of autonomic disorders accompanying hypertensive disease].
    Vrachebnoe delo, 1977, Issue:6

    Topics: Adult; Autonomic Nervous System; Benzimidazoles; Caffeine; Calcium; Female; Gluconates; Humans; Hypertension; Male; Nervous System Diseases; Papaverine; Phenobarbital

1977
Stimulation of caffeine metabolism in the rat by 3-methylcholanthrene.
    Life sciences, 1977, Oct-01, Volume: 21, Issue:7

    Topics: Animals; Caffeine; Kinetics; Male; Methylcholanthrene; Phenobarbital; Rats; Stimulation, Chemical; Time Factors

1977
[An analysis of 22 years' experience with the medicinal treatment of epilepsy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1975, Volume: 75, Issue:3

    Topics: Adult; Anticonvulsants; Bromides; Caffeine; Codeine; Drug Therapy, Combination; Epilepsy; Female; History, 20th Century; Humans; Influenza, Human; Male; Middle Aged; Papaverine; Phenobarbital; Phytotherapy; Plants, Medicinal; Sodium; Tranquilizing Agents; Urea; USSR

1975
The effect of caffeine on barbiturate sleeping time and brain level.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:3

    Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Barbiturates; Brain Chemistry; Caffeine; Drug Interactions; Hexobarbital; Liver; Male; Morphine Derivatives; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sleep; Time Factors

1975
[The effect of psychotropic substances on the mental and physical work capacity of rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1975, Volume: 79, Issue:2

    Topics: Amphetamine; Animals; Benactyzine; Caffeine; Chlordiazepoxide; Cocaine; Diazepam; Disability Evaluation; Electric Stimulation; Learning; Male; Meprobamate; Morphine; Phenobarbital; Psychotropic Drugs; Rats; Reinforcement, Psychology; Self Stimulation; Stimulation, Chemical; Work Capacity Evaluation

1975
Clinical applications of gas chromatograph/mass spectrometer/computer systems.
    Clinical chemistry, 1975, Volume: 21, Issue:9

    Topics: Autoanalysis; Caffeine; Chromatography, Gas; Computers; Diazepam; Evaluation Studies as Topic; Female; Humans; Imides; Indicators and Reagents; Mass Spectrometry; Methods; Milk, Human; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Theobromine; Time Factors

1975
Influence of methylxanthines on aniline disappearance and metabolism in rats.
    Experientia, 1975, Aug-15, Volume: 31, Issue:8

    Topics: Aniline Compounds; Aniline Hydroxylase; Animals; Caffeine; Coffee; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Rats; Tea; Theobromine; Xanthines

1975
On the interaction between caffeine and barbiturates with respect to locomotor activity and brain catecholamines.
    Acta pharmacologica et toxicologica, 1975, Volume: 36, Issue:2

    Topics: Animals; Brain; Caffeine; Clonidine; Dopamine; Drug Interactions; Female; Mice; Motor Activity; Norepinephrine; Pentobarbital; Phenobarbital; Piribedil; Reserpine

1975
Identification and quantification of drugs in human amniotic fluid.
    Research communications in chemical pathology and pharmacology, 1975, Volume: 12, Issue:3

    Topics: Amniotic Fluid; Caffeine; Chromatography, Gas; Computers; Female; Fetal Blood; Humans; Mass Spectrometry; Maternal-Fetal Exchange; Pharmaceutical Preparations; Phenobarbital; Pregnancy; Pregnancy Trimester, Third; Secobarbital; Theobromine

1975
Effects of certain abused drug s on hemolysin forming cells.
    Life sciences, 1975, Dec-15, Volume: 17, Issue:12

    Topics: Amphetamines; Animals; Antibody Formation; Antibody-Producing Cells; Ascorbic Acid; Aspirin; Caffeine; Hemolysin Proteins; Mice; Morphine; Nalorphine; Phenobarbital; Spleen

1975
Gas-chromatographic micro-scale procedure for theophylline, with use of a nitrogen-sensitive detector.
    Clinical chemistry, 1976, Volume: 22, Issue:6

    Topics: Caffeine; Chromatography, Gas; Humans; Microchemistry; Nitrogen; Phenobarbital; Saliva; Theobromine; Theophylline; Xanthines

1976
Perinatal pharmacology and cerebral blood flow.
    Biology of the neonate, 1992, Volume: 62, Issue:4

    Topics: Arteries; Blood Flow Velocity; Caffeine; Carbon Dioxide; Cerebrovascular Circulation; Drug Combinations; Fatty Alcohols; Humans; Indomethacin; Infant, Newborn; Partial Pressure; Phenobarbital; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants

1992
A simplified approach for evaluation of hepatic drug-oxidizing activity with a simultaneous determination of caffeine and trimethadione and their demethylated metabolites in rats with a selective cytochrome P-450 inducer.
    Biopharmaceutics & drug disposition, 1992, Volume: 13, Issue:4

    Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Humans; Liver; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione

1992
On-line measurements of 13C enrichments in rat breath. Non-invasive method for in vivo study of drug enzymatic induction.
    Journal of chromatography, 1991, Jan-02, Volume: 562, Issue:1-2

    Topics: Animals; Breath Tests; Caffeine; Carbon Dioxide; Carbon Isotopes; Cytochrome P-450 Enzyme System; Enzyme Induction; Gas Chromatography-Mass Spectrometry; Kinetics; Male; Methylcholanthrene; Phenobarbital; Rats

1991
[Changes in cerebral blood circulation and their correction in the interparoxysmal period of epilepsy].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1990, Volume: 90, Issue:6

    Topics: Adolescent; Adult; Brain Ischemia; Caffeine; Cerebrovascular Circulation; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Papaverine; Phenobarbital; Regional Blood Flow

1990
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
    Journal of chromatography, 1990, Aug-03, Volume: 529, Issue:2

    Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines

1990
Depressive effects of lipid peroxides mediated via a purine receptor. Effect of lipid peroxide on the cortical synaptosomal GTPase activity.
    Biochemical pharmacology, 1990, Oct-01, Volume: 40, Issue:7

    Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Circadian Rhythm; Down-Regulation; GTP Phosphohydrolases; Lipid Peroxides; Locomotion; Mice; Phenobarbital; Rats; Receptors, Purinergic; Synaptosomes

1990
[Application of convolution curve method for simultaneous determination of four components in somidon].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1990, Volume: 25, Issue:3

    Topics: Aminopyrine; Analgesics; Caffeine; Drug Combinations; Methods; Phenacetin; Phenobarbital; Tablets

1990
Methylcholanthrene but not phenobarbital enhances caffeine and theophylline metabolism in cultured adult human hepatocytes.
    Biochemical pharmacology, 1990, Jan-01, Volume: 39, Issue:1

    Topics: Adult; Biotransformation; Caffeine; Cells, Cultured; Humans; Kinetics; Liver; Methylcholanthrene; Phenobarbital; Theophylline

1990
Effect of methylxanthines on acetaminophen hepatotoxicity in various induction states.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:1

    Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Body Temperature; Caffeine; Glutathione; Imines; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Theobromine; Theophylline

1990
[Granulomatous processes in the lungs].
    Ceskoslovenska patologie, 1990, Volume: 26, Issue:2

    Topics: Acrylonitrile; Adult; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Granuloma; Humans; Lung Diseases; Male; Middle Aged; Occupational Diseases; Phenobarbital; Substance Abuse, Intravenous; Textile Industry

1990
[Plasma determination of 7 common drugs by high performance liquid chromatography].
    Annales de biologie clinique, 1989, Volume: 47, Issue:2

    Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid

1989
Presence and properties of cAMP phosphodiesterase from promastigote forms of Leishmania tropica and Leishmania donovani.
    Comparative biochemistry and physiology. B, Comparative biochemistry, 1989, Volume: 93, Issue:4

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Calcium; Hydrogen-Ion Concentration; Kinetics; Leishmania donovani; Leishmania tropica; Magnesium; Phenobarbital; Substrate Specificity; Temperature; Theophylline; Trifluoperazine

1989
[A quick DC method for simultaneous quantitative determination of paracetamol, caffeine, phenobarbital and propyphenazone in plasma].
    Pharmaceutica acta Helvetiae, 1989, Volume: 64, Issue:1

    Topics: Acetaminophen; Antipyrine; Caffeine; Humans; Phenobarbital

1989
An evaluation of the results of a drug sample analysis.
    Bulletin on narcotics, 1989, Volume: 41, Issue:1-2

    Topics: Amphetamines; Caffeine; Cocaine; Drug Contamination; Heroin; Humans; Illicit Drugs; Lidocaine; Methaqualone; Phenobarbital; Procaine; Spain; Substance-Related Disorders

1989
Abuse of a commonly prescribed analgesic preparation.
    Canadian Medical Association journal, 1985, Aug-15, Volume: 133, Issue:4

    Topics: Adult; Analgesics, Opioid; Aspirin; Barbiturates; Caffeine; Codeine; Drug Combinations; Female; Humans; Inactivation, Metabolic; Male; Phenacetin; Phenobarbital; Substance-Related Disorders

1985
[Possibilities of modelling of an undesirable phenomenon-- non-alcoholic substance abuse in society].
    Ceskoslovenske zdravotnictvi, 1988, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Alcohol Drinking; Aspirin; Caffeine; Child; Codeine; Czechoslovakia; Drug Combinations; Humans; Models, Theoretical; Phenobarbital; Socioeconomic Factors; Substance-Related Disorders

1988
[Application of dynamic programming for quantitative analysis of qutong tablet and keganmin tablet].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1988, Volume: 23, Issue:10

    Topics: Aminopyrine; Caffeine; Drug Combinations; Mathematics; Methods; Phenacetin; Phenobarbital; Tablets

1988
Study of deutero-isotopomer-induced inhibition of caffeine and phenobarbitone binding to human serum albumin.
    Biochemical pharmacology, 1988, Apr-01, Volume: 37, Issue:7

    Topics: Binding Sites; Caffeine; Deuterium; Humans; Phenobarbital; Protein Binding; Serum Albumin

1988
Effect of caffeine on the hepatic microsomal mixed function oxidase system during phenobarbital and benzo[a]pyrene treatment in rats.
    Toxicology letters, 1988, Volume: 42, Issue:2

    Topics: Aminopyrine N-Demethylase; Animals; Benzo(a)pyrene; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1988
[Significance of the interaction between analgesic-antipyretics and ethanol in forensic medicine investigations].
    Bratislavske lekarske listy, 1987, Volume: 87, Issue:4

    Topics: Accidents, Traffic; Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Codeine; Drug Combinations; Drug Interactions; Ethanol; Forensic Medicine; Guaifenesin; Humans; Male; Middle Aged; Phenobarbital; Psychomotor Performance

1987
Simultaneous administration of caffeine and phenobarbitone in infants with apnea.
    The Journal of pediatrics, 1987, Volume: 110, Issue:4

    Topics: Apnea; Caffeine; Drug Therapy, Combination; Half-Life; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital

1987
Metabolism of caffeine to 6-amino-5-[N-methylformylamino]-1,3-dimethyluracil in the isolated, perfused liver from control or phenobarbital-, beta-naphthoflavone- and 3-methylcholanthrene-pretreated rats.
    Toxicology letters, 1987, Volume: 38, Issue:1-2

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Drug Interactions; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Uracil

1987
[The effect of intrahepatic cholestasis in pregnancy on various forms of cytochrome P-450-dependent biotransformation reactions].
    Die Pharmazie, 1987, Volume: 42, Issue:5

    Topics: Biotransformation; Caffeine; Cholestasis, Intrahepatic; Cytochrome P-450 Enzyme System; Female; Humans; Isoenzymes; Kinetics; Phenobarbital; Pregnancy; Pregnancy Complications

1987
[Peculiarities of drug therapy in childhood].
    Monatsschrift Kinderheilkunde : Organ der Deutschen Gesellschaft fur Kinderheilkunde, 1986, Volume: 134, Issue:11

    Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone; Drug Therapy; Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Receptors, Drug; Theophylline; Tissue Distribution

1986
High performance liquid chromatographic procedure for the simultaneous determination of theophylline, caffeine, and phenobarbital in neonates.
    Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie, 1985, Volume: 23, Issue:5

    Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Phenobarbital; Spectrophotometry, Ultraviolet; Theophylline

1985
[Post-mortem toxicological analysis and comparison of concentrations of drugs in organs and bones].
    Acta pharmaceutica Hungarica, 1985, Volume: 55, Issue:4

    Topics: Amobarbital; Autopsy; Bone and Bones; Caffeine; Gas Chromatography-Mass Spectrometry; Glutethimide; Humans; Phenacetin; Phenobarbital; Tissue Distribution

1985
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 187, Issue:1

    Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium

1973
On the pharmacology of cortical evoked potentials.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 199, Issue:1

    Topics: Acetamides; Animals; Caffeine; Cats; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Corpus Callosum; Dextroamphetamine; Electric Stimulation; Evoked Potentials; Phenobarbital; Pyrrolidinones; Reflex, Monosynaptic; Sciatic Nerve; Stereotaxic Techniques; Synaptic Transmission; Thiopental

1972
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
    Die Pharmazie, 1974, Volume: 29, Issue:7

    Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine

1974
[Germination and growth inhibitory effect of thalidomide and different analeptics on embryos of Lepidium sativum].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:9

    Topics: Aminobutyrates; Caffeine; Camphor; Carbonates; Central Nervous System Stimulants; Depression, Chemical; Ephedrine; Ethanolamines; Nikethamide; Nitrates; Pentylenetetrazole; Phenobarbital; Seeds; Sodium; Strychnine; Sympathomimetics; Thalidomide

1969
Effects of drugs acting alone and in combination on the motor activity of intact mice.
    British journal of pharmacology, 1970, Volume: 39, Issue:4

    Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central Nervous System Stimulants; Chlorpromazine; Diazepam; Diphenhydramine; Female; Glutamates; Hydroxybutyrates; Lactones; Meperidine; Meprobamate; Mice; Motor Activity; Nikethamide; Phenobarbital; Picrotoxin; Promethazine; Reflex; Scopolamine; Seizures; Strychnine; Tranquilizing Agents

1970
Effect of caffeine on hepatic microsomal cytochrome P-450.
    Biochemical pharmacology, 1970, Volume: 19, Issue:7

    Topics: Acetanilides; Adrenalectomy; Animals; Anisoles; Caffeine; Cytochromes; Enzyme Induction; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitriles; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry; Sulfites; Time Factors

1970
Effect on pseudoconditioning of drugs with known central nervous activity.
    Psychopharmacologia, 1974, Volume: 38, Issue:3

    Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione

1974
[Drug permeation through synthetic lipid membranes. Permeability of lecithin-collodium membranes for drugs and metabolites].
    Die Pharmazie, 1974, Volume: 29, Issue:9

    Topics: Buffers; Caffeine; Diffusion; Hexobarbital; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Models, Chemical; Papaverine; Phenobarbital; Phenytoin; Phosphatidylcholines; Quinine; Salicylates; Solutions; Time Factors

1974
Factors affecting the metabolism of phenacetin. II. Effect of aspirin, caffeine, codeine, ethanol and phenobarbital on the metabolism of (acetyl-14C)-phenacetin in the rat.
    Xenobiotica; the fate of foreign compounds in biological systems, 1974, Volume: 4, Issue:8

    Topics: Acetates; Administration, Oral; Animals; Aspirin; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Thin Layer; Codeine; Ethanol; Feces; Female; Phenacetin; Phenobarbital; Rats; Respiration; Time Factors

1974
[Effect in vitro of some drugs on albumin-bilirubin binding].
    Minerva pediatrica, 1972, Nov-24, Volume: 24, Issue:41

    Topics: Anti-Bacterial Agents; Benzoates; Bilirubin; Caffeine; Digitalis Glycosides; In Vitro Techniques; Phenobarbital; Protein Binding; Serum Albumin; Sulfadimethoxine

1972
[Comparative study of Lyell's and Stevens-Johnson syndromes: etiologic role of drugs].
    Schweizerische medizinische Wochenschrift, 1972, Dec-23, Volume: 102, Issue:51

    Topics: Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Codeine; Female; Humans; Hydantoins; Infant; Infant, Newborn; Male; Middle Aged; Penicillins; Phenacetin; Phenobarbital; Phenolphthaleins; Phenylbutazone; Promethazine; Stevens-Johnson Syndrome; Sulfamethoxypyridazine; Vaccines

1972
The effect of daily ingestion of caffeine on the microsomal enzymes of rat liver.
    Food and cosmetics toxicology, 1973, Volume: 11, Issue:1

    Topics: Acetanilides; Administration, Oral; Aminopyrine N-Demethylase; Animals; Caffeine; Cytochrome P-450 Enzyme System; Cytochromes; Drug Synergism; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical; Time Factors

1973
Use of stable isotopes in measuring low concentrations of drugs and drug metabolites by GC-MS-COM procedures.
    Clinical chemistry, 1973, Volume: 19, Issue:8

    Topics: Amniotic Fluid; Barbiturates; Caffeine; Carbon Isotopes; Child; Chromatography, Gas; Colostrum; Computers; Fatty Acids; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methods; Microchemistry; Milk, Human; Phenobarbital; Phenytoin; Pregnancy

1973
Application of quantitative thin-layer chromatography in drug assay and stability testing. Determination of codeine phosphate, noscapine, diphenhydramine hydrochloride, phenylephrine hydrochloride, caffeine, etofyllin, phenobarbital and thiamine hydrochlo
    Journal of chromatography, 1973, Jul-18, Volume: 82, Issue:1

    Topics: Autoanalysis; Caffeine; Chromatography, Thin Layer; Codeine; Diphenhydramine; Drug Combinations; Drug Stability; Methods; Noscapine; Pharmaceutical Preparations; Phenobarbital; Phenylephrine; Spectrum Analysis; Theophylline; Thiamine

1973
The use of gass chromatography-mass spectrometry methods in perinatal pharmacology.
    Advances in biochemical psychopharmacology, 1973, Volume: 7

    Topics: Barbiturates; Caffeine; Chromatography, Gas; Female; Fetus; Humans; Infant, Newborn; Mass Spectrometry; Maternal-Fetal Exchange; Meperidine; Phenobarbital; Pregnancy; Secobarbital

1973
[Treatment of extrapyramidal hyperkinesis].
    Vrachebnoe delo, 1973, Volume: 7, Issue:7

    Topics: Adolescent; Adult; Ambulatory Care; Basal Ganglia Diseases; Benzimidazoles; Benzyl Compounds; Bromine; Caffeine; Chronic Disease; Drug Combinations; Humans; Hyperkinesis; Male; Middle Aged; Papaverine; Parasympatholytics; Phenobarbital; Powders; Urea; Valerates

1973
Proceedings: Accentuation of chlorambucil effect by various additives on rat tumour cells in culture.
    British journal of cancer, 1974, Volume: 29, Issue:1

    Topics: Animals; Caffeine; Cells, Cultured; Chlorambucil; Drug Synergism; Neoplasms, Experimental; Phenobarbital; Rats; Vitamin A

1974
Body consciousness in states of pharmacological depression and arousal.
    Neuropharmacology, 1970, Volume: 9, Issue:2

    Topics: Arousal; Barbiturates; Caffeine; Consciousness; Female; Humans; Male; Perception; Phenobarbital; Projective Techniques; Psychopharmacology

1970
[Effects of various drugs on metabolism of the skeletal muscle. 2. Effects of procaine, pentobarbital and phenobarbital on the stimulated respiration of the skeletal muscle].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1971, Volume: 67, Issue:4

    Topics: Animals; Anura; Caffeine; Depression, Chemical; Dinitrophenols; Edetic Acid; In Vitro Techniques; Muscles; Ouabain; Oxygen Consumption; Pentobarbital; Phenobarbital; Potassium; Procaine; Ranidae; Stimulation, Chemical; Sucrose

1971
A rapid procedure for the isolation of drugs and drug metabolites from plasma.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 37

    Topics: 1-Propanol; Animals; Caffeine; Carbon Isotopes; Carbonates; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Humans; Mass Spectrometry; Methods; Methylation; Phenobarbital; Potassium; Rats; Silicon

1972
[Studies on solubilizing agents. IV. Dielectric constant correlations with drug solubility in the mixtures of glycols and their derivatives with water].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:3

    Topics: Caffeine; Glycols; Pharmaceutic Aids; Phenobarbital; Salicylates; Solubility; Solvents; Water

1972
Neuropharmacological studies of imidazole-4-acetic acid actions in the mouse and rat.
    Neuropharmacology, 1971, Volume: 10, Issue:21

    Topics: Acetates; Animals; Ataxia; Behavior; Caffeine; Catalepsy; Central Nervous System; Drug Interactions; Drug Synergism; Electroencephalography; Humans; Hydroxybutyrates; Imidazoles; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sleep; Stimulation, Chemical; Strychnine; Time Factors

1971
[Pretesting of drugs using lower and higher plants. II. Effect of phenazetin and various substances frequently combined with it, on the shape and growth of Micrasterias americana].
    Arzneimittel-Forschung, 1971, Volume: 21, Issue:6

    Topics: Antineoplastic Agents; Biological Assay; Caffeine; Cell Division; Cell Transformation, Neoplastic; Drug Synergism; Eukaryota; Phenacetin; Phenobarbital; Quinine

1971
Influence of hydrophobic character on the relative rate of oxidation of drugs by rat liver microsomes.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:9

    Topics: Aniline Compounds; Animals; Barbiturates; Caffeine; Chemical Phenomena; Chemistry, Physical; Chlorine; Codeine; Ephedrine; Fatty Alcohols; Hexobarbital; Kinetics; Male; Mathematics; Microsomes, Liver; Mixed Function Oxygenases; Naphthalenes; Oxidoreductases; Phenobarbital; Physostigmine; Rats; Solubility; Structure-Activity Relationship

1971
[The pain syndrome of the edentulous alveolar crest and its treatment].
    Revue de stomatologie et de chirurgie maxillo-faciale, 1969, Volume: 70, Issue:2

    Topics: Administration, Topical; Alveolar Process; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Caffeine; Chlorpromazine; Codeine; Humans; Hyaluronoglucosaminidase; Hydrocortisone; Mouth, Edentulous; Pain; Phenobarbital; Procaine; Promethazine

1969
[Treatment of epilepsy with a combination of Gardenal and caffeine. Presentation of 84 cases].
    Hospital (Rio de Janeiro, Brazil), 1968, Volume: 74, Issue:3

    Topics: Adolescent; Adult; Caffeine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital

1968
[Treatment of epilepsy using a combination of Gardenal and caffeine. Report of 84 cases].
    Hospital (Rio de Janeiro, Brazil), 1968, Volume: 74, Issue:3

    Topics: Adolescent; Adult; Caffeine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital

1968
Nicotine injections as the conditioned stimulus in discrimination learning.
    Psychopharmacologia, 1969, Volume: 15, Issue:5

    Topics: Amphetamine; Animals; Apomorphine; Caffeine; Chlordiazepoxide; Chlorisondamine; Conditioning, Operant; Discrimination Learning; Electroshock; Epinephrine; Gallamine Triethiodide; Male; Mecamylamine; Nicotine; Noise; Phenobarbital; Physostigmine; Rats; Water

1969
Nature of the effect of caffeine on the drug-metabolizing enzymes.
    Archives of biochemistry and biophysics, 1969, Volume: 134, Issue:2

    Topics: 17-Hydroxycorticosteroids; Acetanilides; Amino Acids; Aminopyrine; Aniline Compounds; Animals; Caffeine; Cytochromes; Dactinomycin; Drug Antagonism; Enzyme Induction; Female; Humans; Male; Methylation; Microsomes, Liver; Oxidoreductases; Phenobarbital; Pregnanes; Pyridones; Rats; Stimulation, Chemical; Time Factors; Zoxazolamine

1969
[Direct quantitative evaluation of thin layer chromatogramms by remission- and fluorescence measurement. 2. Determination of drugs in 2 combination preparations by remission measurements].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:11

    Topics: Amitriptyline; Aspirin; Caffeine; Capsules; Chlordiazepoxide; Chromatography, Thin Layer; Codeine; Phenacetin; Phenobarbital; Phosphates; Spectrophotometry; Tablets

1969
[Quantitative determination of salicylamide, phenacetin, caffeine, diphenhydramine chlorhydrate, luminal combinations].
    Turk hijiyen ve tecrubi biyoloji dergisi, 1969, Volume: 29, Issue:2

    Topics: Caffeine; Diphenhydramine; Drug Combinations; Phenacetin; Phenobarbital; Salicylamides

1969
Estimation of mean potency and content uniformity of tablets: a new approach.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:2

    Topics: Atropine; Caffeine; Chemistry, Pharmaceutical; Computers; Diethylstilbestrol; Drug Compounding; Drug Tolerance; Isoniazid; Mestranol; Methyltestosterone; Models, Theoretical; Paramethasone; Pharmaceutical Preparations; Phenobarbital; Sulfates; Tablets

1970
[Therapy of epilepsy].
    Therapeutische Umschau. Revue therapeutique, 1967, Volume: 24, Issue:12

    Topics: Amphetamine; Anticonvulsants; Caffeine; Child; Drug Synergism; Epilepsy; Humans; Hydantoins; Phenobarbital

1967
[Further studies on the growth inhibitory effect of hypnotics in embryos of Sinapis alba].
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:12

    Topics: Caffeine; Chloral Hydrate; Chlorophyll; Depression, Chemical; Embryo, Mammalian; Embryo, Nonmammalian; Female; Glutethimide; Mustard Plant; Phenobarbital; Plants, Medicinal; Pregnancy; Procaine; Thalidomide

1967
[The influence of centrally acting drugs on directional hearing of normal subjects in a free acoustic field].
    Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete, 1968, Volume: 47, Issue:5

    Topics: Aged; Audiometry; Auditory Perception; Benactyzine; Caffeine; Chlorpromazine; Female; Humans; Male; Meprobamate; Middle Aged; Phenobarbital; Strychnine

1968
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
    Canadian journal of biochemistry, 1968, Volume: 46, Issue:4

    Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione

1968
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:2

    Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental

1968
Paroxysmal dystonic choreoathetosis. A family study and review of the literature.
    Neurology, 1968, Volume: 18, Issue:5

    Topics: Adult; Aged; Amobarbital; Athetosis; Atropine; Benzoates; Caffeine; Child, Preschool; Chorea; Coffee; Consciousness; Electroencephalography; Fatigue; Female; Functional Laterality; Humans; Male; Middle Aged; Motion Pictures; Muscles; Muscular Diseases; Neostigmine; Pedigree; Phenobarbital; Phenytoin; Phytotherapy; Stress, Physiological; Suggestion

1968
Interactions between pharmaceutical compounds by thermal methods.
    Journal of pharmaceutical sciences, 1969, Volume: 58, Issue:3

    Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K

1969
[The influence of centrally active drugs on sound perception in normally hearing subjects using a binaural speech test].
    Zeitschrift fur Laryngologie, Rhinologie, Otologie und ihre Grenzgebiete, 1965, Volume: 44, Issue:9

    Topics: Benactyzine; Caffeine; Chlorpromazine; Hearing; Hearing Tests; Humans; Meprobamate; Phenobarbital; Psychopharmacology; Strychnine

1965
Possible role of Ca ions in the resting metabolism of frog sartorius muscle during potassium depolarization.
    Journal of cellular physiology, 1966, Volume: 67, Issue:1

    Topics: Animals; Anura; Caffeine; Calcium; Calcium Chloride; Cell Membrane Permeability; Electrophysiology; In Vitro Techniques; Isotonic Solutions; Muscles; Oxygen Consumption; Phenobarbital; Physostigmine; Potassium; Procaine

1966
Influence exerted on auditory fatigue by some calmatives and stimulants of the central nervous system.
    Acta oto-laryngologica, 1966, Volume: 62, Issue:6

    Topics: Adolescent; Adult; Audiometry; Caffeine; Fatigue; Female; Hearing; Humans; Lobeline; Male; Meprobamate; Middle Aged; Phenobarbital; Reticular Formation; Strychnine; Tranquilizing Agents

1966
[New drugs. Premenstrin. (Tablets)].
    Ceskoslovenska farmacie, 1966, Volume: 15, Issue:9

    Topics: Caffeine; Ergotamine; Female; Guaifenesin; Phenobarbital; Premenstrual Syndrome; Tablets

1966
Determination of acetylsalicylic acid and barbiturate combinations in dosage forms.
    Journal of pharmaceutical sciences, 1967, Volume: 56, Issue:1

    Topics: Amobarbital; Aspirin; Atropa belladonna; Barbiturates; Caffeine; Dextroamphetamine; Dosage Forms; Phenacetin; Phenobarbital; Plants, Medicinal; Plants, Toxic; Potentiometry

1967
[EEG studies of cases with epileptic and intricate somatic manifestations].
    Revue neurologique, 1967, Volume: 117, Issue:1

    Topics: Adult; Asthma; Atropa belladonna; Caffeine; Child; Drug Tolerance; Eczema; Electroencephalography; Epilepsy; Humans; Hypersensitivity; Male; Migraine Disorders; Phenobarbital; Phytotherapy; Plants, Medicinal; Plants, Toxic

1967
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
    Epilepsia, 1984, Volume: 25, Issue:4

    Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline

1984
Programming of rat hepatic arylhydrocarbon hydroxylase activity during late neonatal period.
    Proceedings of the Western Pharmacology Society, 1982, Volume: 25

    Topics: Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Caffeine; DNA; Female; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains

1982
[Relationship between the placental-fetal index (PFI) and the toxic and teratogenic effect in the fetuses of mothers treated with sedalgin during pregnancy].
    Eksperimentalna meditsina i morfologiia, 1983, Volume: 22, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Fetus; Phenacetin; Phenobarbital; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Time Factors

1983
Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:1

    Topics: Aggression; Animals; Bites and Stings; Caffeine; Chlordiazepoxide; Chlorpromazine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diazepam; Electroshock; Ethanol; Female; Humans; Male; Morphine; Nicotine; Phenobarbital; Saimiri

1983
Interactions of caffeine and phenobarbital on sister chromatid exchanges in rat liver epithelial cell lines treated with 2-acetyl-aminofluorene and N-acetoxy-2-acetylaminofluorene.
    Cell biology international reports, 1984, Volume: 8, Issue:4

    Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Caffeine; Cell Line; Cells, Cultured; Crossing Over, Genetic; Epithelial Cells; Epithelium; Liver; Metaphase; Phenobarbital; Rats; Sister Chromatid Exchange

1984
Assessment of the cytochrome P-448 dependent liver enzyme system by a caffeine breath test.
    European journal of clinical pharmacology, 1981, Volume: 21, Issue:1

    Topics: Adult; Animals; Breath Tests; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Cytochrome P-450 CYP1A2; Cytochromes; Dealkylation; Enzyme Induction; Humans; Liver; Liver Cirrhosis; Male; Methylcholanthrene; Middle Aged; Phenobarbital; Rats; Rats, Inbred Strains; Tobacco Use Disorder

1981
Sleep spindles: pharmacological effects in humans.
    Sleep, 1982, Volume: 5, Issue:1

    Topics: Atropine; Azepines; Caffeine; Cerebral Cortex; Computers; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Flurazepam; Haloperidol; Humans; N-Methylscopolamine; Phenobarbital; Scopolamine; Scopolamine Derivatives; Sleep Stages; Thalidomide; Tryptophan

1982
Effects of chlorpromazine and other drugs acting on the central nervous system on human sperm motility.
    European journal of clinical pharmacology, 1982, Volume: 22, Issue:5

    Topics: Caffeine; Central Nervous System; Chlorpromazine; Diazepam; Humans; In Vitro Techniques; Male; Phenobarbital; Phenytoin; Sperm Motility

1982
[A comparative pharmacokinetic study for tablet and suppository formulations of a combination product of caffeine, ethaverine, propyphenazone, paracetamol and phenobarbital (author's transl)].
    Arzneimittel-Forschung, 1981, Volume: 31, Issue:1

    Topics: Acetaminophen; Adult; Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Kinetics; Male; Papaverine; Phenobarbital; Rectum; Suppositories; Tablets

1981
Caffeine antagonizes several central effects of diazepam.
    Life sciences, 1981, May-18, Volume: 28, Issue:20

    Topics: Aggression; Animals; Caffeine; Cats; Central Nervous System; Conflict, Psychological; Diazepam; Humans; Hypothalamus; Muscle Tonus; Pentylenetetrazole; Phenobarbital; Spinal Cord

1981
In vivo N7 methylation of theophylline to caffeine in premature infants. Studies with use of stable isotopes.
    Developmental pharmacology and therapeutics, 1981, Volume: 2, Issue:3

    Topics: Caffeine; Carbon Isotopes; Humans; Infant, Newborn; Infant, Premature; Methylation; Nitrogen Isotopes; Phenobarbital; Theophylline; Time Factors

1981
[Modification of the caffeine metabolism in mouse liver slices by previous treatment of the experimental animals with ethanol, aminophenazone and phenobarbital].
    Zeitschrift fur Ernahrungswissenschaft, 1980, Volume: 19, Issue:3

    Topics: Aminopyrine; Animals; Caffeine; Dose-Response Relationship, Drug; Ethanol; In Vitro Techniques; Liver; Male; Mice; Phenobarbital; Rats; Species Specificity

1980
[Reciprocal action between caffeine, other stimulants and drugs].
    Zeitschrift fur Ernahrungswissenschaft, 1980, Volume: 19, Issue:4

    Topics: Analgesics; Animals; Barbiturates; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Humans; Methylcholanthrene; Nicotinic Acids; Phenobarbital; Smoking; Theobromine; Xanthines

1980
Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:7

    Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Caffeine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochromes b5; Dexamethasone; Enzyme Induction; Female; Hydroxylation; Isoenzymes; Macaca fascicularis; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxazines; Oxidation-Reduction; Phenobarbital; Sex Factors; Species Specificity; Testosterone

1995
Modulation of diethylnitrosamine carcinogenesis in rat liver and oesophagus.
    Journal of cellular biochemistry, 1994, Volume: 56, Issue:4

    Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Caffeine; Diethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Female; Liver Neoplasms, Experimental; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred Strains; Survival; Theophylline; Tretinoin

1994
Impurities, adulterants and diluents of illicit heroin. Changes during a 12-year period.
    Forensic science international, 1994, Volume: 64, Issue:2-3

    Topics: Acetaminophen; Caffeine; Carbohydrates; Denmark; Drug Contamination; Heroin; Hydrogen-Ion Concentration; Illicit Drugs; Lactose; Morphine; Noscapine; Papaverine; Phenobarbital; Procaine

1994
Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents.
    Biochemical pharmacology, 1993, Aug-03, Volume: 46, Issue:3

    Topics: Acetaminophen; Acetone; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Activation; Female; Imines; Isoenzymes; Kinetics; Liver Diseases; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital

1993
Anticonvulsant activity of phenobarbital and valproate against maximal electroshock in mice during chronic treatment with caffeine and caffeine discontinuation.
    Epilepsia, 1996, Volume: 37, Issue:3

    Topics: Animals; Anticonvulsants; Caffeine; Electroshock; Male; Mice; Phenobarbital; Seizures; Valproic Acid

1996
In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): substrate activities and effects of inducers.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:11

    Topics: Animals; Antipyrine; beta-Naphthoflavone; Biotransformation; Blotting, Western; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Goats; Isoniazid; Microsomes, Liver; Phenobarbital; Sulfamethazine; Troleandomycin

1996
[Spasmophilia in children and the anticonvulsant properties of a new Ukrainian preparation containing a pyrimidine derivative].
    Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994), 1998, Volume: 44, Issue:5-6

    Topics: Animals; Anticonvulsants; Aspirin; Caffeine; Child; Convulsants; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Humans; Mice; Pentylenetetrazole; Phenobarbital; Tablets; Tetany

1998
Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats.
    Biochemical pharmacology, 1998, May-01, Volume: 55, Issue:9

    Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; Dexamethasone; Female; Humans; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Troleandomycin; Uric Acid

1998
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
    Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3

    Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics

1999
Influence of caffeine on allyl alcohol-induced hepatotoxicity in rats. I. In vivo study.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2001, Volume: 20, Issue:2

    Topics: Acrolein; Alanine Transaminase; Alcohol Dehydrogenase; Animals; Caffeine; Chemical and Drug Induced Liver Injury; Drug Interactions; Enzyme Inhibitors; Fomepizole; Glutathione; Hepatocytes; Liver; Male; Phenobarbital; Propanols; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds

2001
Glucose transporter type 1 deficiency syndrome (Glut1DS): methylxanthines potentiate GLUT1 haploinsufficiency in vitro.
    Pediatric research, 2001, Volume: 50, Issue:2

    Topics: 3-O-Methylglucose; Adolescent; Caffeine; Case-Control Studies; Child; Erythrocytes; Female; Humans; In Vitro Techniques; Kinetics; Male; Monosaccharide Transport Proteins; Mutation; Phenobarbital; Syndrome; Theophylline

2001
Effect of orally administered guanosine on seizures and death induced by glutamatergic agents.
    Brain research, 2001, Sep-07, Volume: 912, Issue:2

    Topics: Animals; Brain; Caffeine; Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Elapid Venoms; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine; Kainic Acid; Male; Mice; Neuroprotective Agents; Phenobarbital; Phosphodiesterase Inhibitors; Quinolinic Acid; Receptors, Purinergic P1

2001
HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets.
    Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:9

    Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Pharmaceutical Preparations; Phenobarbital; Reproducibility of Results; Tablets

2002
[Simultaneous determination of four components in the compound child phenobarbital tablet using ultraviolet spectrophotometry].
    Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University, 2002, Feb-28, Volume: 27, Issue:1

    Topics: Aspirin; Caffeine; Child; Child, Preschool; Drug Compounding; Humans; Infant; Phenacetin; Phenobarbital; Spectrophotometry, Ultraviolet; Tablets

2002
Investigation of some complexes formed in solution by caffeine. IV. Interactions between caffeine and sulfathiazole, sulfadiazine, p-aminobenzoic acid, benzocaine, phenobarbital, and barbital.
    Journal of the American Pharmaceutical Association. American Pharmaceutical Association, 1954, Volume: 43, Issue:6 1

    Topics: 4-Aminobenzoic Acid; Aminobenzoates; Barbital; Barbiturates; Benzocaine; Caffeine; Pharmaceutical Solutions; Phenobarbital; Solutions; Sulfadiazine; Sulfathiazole; Sulfathiazoles

1954
[Epilepsy therapy with the combination preparation centronal compositum].
    Munchener medizinische Wochenschrift (1950), 1957, Jan-25, Volume: 99, Issue:4

    Topics: Aminopyrine; Caffeine; Epilepsy; Humans; Hydantoins; Phenobarbital; Porphyrins

1957
The action exercised by the thymus and several neurotropic substances in experimental cancer.
    Acta - Unio Internationalis Contra Cancrum, 1957, Volume: 13, Issue:3

    Topics: Animals; Benzoates; Caffeine; Humans; Neoplasms; Neoplasms, Experimental; Phenobarbital; Thymus Extracts

1957
[Hypoglycemic coma induced by small doses of insulin in the treatment of psychiatric diseases; combination of insulin with luminal and caffeine. I].
    Suvremenna meditsina, 1957, Volume: 8, Issue:10

    Topics: Caffeine; Coma; Convulsive Therapy; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Mental Disorders; Phenobarbital

1957
[Studies on the effect of neurotropic substances caffeine-sodium benzoate, luminal sodium, acetylcholine and atropine on anti-anemic intrinsic factor].
    Nauchni trudove na Visshiia meditsinski institut, Sofiia, 1960, Volume: 39(2)

    Topics: Acetylcholine; Atropine; Benzoates; Caffeine; Drug Combinations; Gastric Juice; Humans; Intrinsic Factor; Phenobarbital; Sodium; Sodium Benzoate

1960
[The modification of flicker fusion frequency in man by phenylpyrrolidinopentane, Katovit, caffeine and phenylethylbarbituric acid].
    Die Medizinische Welt, 1961, Dec-23, Volume: 51

    Topics: Ascorbic Acid; Caffeine; Flicker Fusion; Folic Acid; Humans; Male; Phenobarbital; Pyrrolidines; Sympathomimetics; Vitamin B Complex; Vitamins

1961
[Some possibilities for the use of thin-layer chromatography without binding agents in drug analysis. 3. Qualitative detection of purines and barbiturates used in prescriptions].
    Die Pharmazie, 1963, Volume: 18

    Topics: Aminophylline; Barbiturates; Caffeine; Chromatography, Thin Layer; Phenobarbital; Purines; Substance Abuse Detection; Theobromine; Theophylline

1963
[THE CUFF METHOD FOR THE ANTALGIC EVALUATION OF DIFFERENT DRUGS].
    El Dia medico, 1963, Sep-05, Volume: 35

    Topics: Aminopyrine; Arthritis; Arthritis, Rheumatoid; Aspirin; Caffeine; Gout; Osteoarthritis; Phenobarbital; Phenylbutazone; Prednisolone; Procaine; Sciatica; Tendinopathy

1963
[GENESIS, CLASSIFICATION AND THERAPY OF LOSS OF CONSCIOUSNESS].
    Monatsschrift fur Kinderheilkunde, 1963, Volume: 111

    Topics: Caffeine; Child; Classification; Electroencephalography; Epilepsy; Epilepsy, Absence; Humans; Oxyphenbutazone; Phenobarbital; Phenytoin; Physiology; Pyrrolidinones; Unconsciousness

1963
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
    Svenska lakartidningen, 1964, Mar-25, Volume: 61

    Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Caffeine; Ephedrine; Female; Fetal Death; Fetal Development; Humans; Infant; Infant, Newborn; Infant, Premature; Meclizine; Pharmacology; Phenobarbital; Pregnancy; Prochlorperazine; Promethazine

1964
THE STUDY OF CHANGES IN THE SO-CALLED SUCCESSIVE CONTRAST IN NEUROLOGY.
    Activitas nervosa superior, 1964, Volume: 6

    Topics: Afterimage; Amphetamine; Arteriosclerosis; Brain Concussion; Brain Injuries; Brain Neoplasms; Bromides; Caffeine; Cerebrovascular Disorders; Goiter; Graves Disease; Humans; Lymph Nodes; Multiple Sclerosis; Neurasthenia; Neurology; Neurotic Disorders; Occupational Diseases; Optic Atrophy; Phenobarbital; Tetany; Tuberculosis; Tuberculosis, Lymph Node

1964
[SPASMO-DOLVIRAN "BAYER" IN GENERAL PRACTICE].
    Deutsches medizinisches Journal, 1964, Feb-05, Volume: 15

    Topics: Aspirin; Caffeine; Codeine; Colic; Family Practice; General Practice; Humans; Migraine Disorders; Phenacetin; Phenobarbital; Spasm

1964
[TREATMENT OF PATIENTS WITH EPILEPSY WITH FREQUENT PETIT MAL SEIZURES].
    Sovetskaia meditsina, 1964, Volume: 27

    Topics: Anticonvulsants; Caffeine; Drug Therapy; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Seizures

1964
DRUGS FOR HEADACHE OF MIGRAINOUS, VASCULAR OR MUSCULAR ORIGIN.
    Canadian Medical Association journal, 1964, Jul-25, Volume: 91

    Topics: Aspirin; Caffeine; Cardiovascular Agents; Ergot Alkaloids; Ergotamine; Headache; Humans; Meprobamate; Methysergide; Migraine Disorders; Oxytocics; Pharmacology; Phenacetin; Phenobarbital; Scopolamine; Toxicology

1964
[ON A NEW METHOD OF RECORDING MOVEMENT IN THE LABORATORY ANIMAL MAINTAINED IN ITS REARING ENVIRONMENT--ITS APPLICATION TO THE STUDY OF SOME BEHAVIOR-MODIFYING AGENTS].
    Archives internationales de pharmacodynamie et de therapie, 1964, Sep-01, Volume: 151

    Topics: Amphetamine; Amphetamines; Animals; Animals, Laboratory; Barbiturates; Behavior, Animal; Caffeine; Chlorpromazine; Cinnamates; Cyanides; Heterocyclic Compounds; Hypnotics and Sedatives; Injections, Intraperitoneal; Mice; Morphine; Movement; Pharmacology; Phenobarbital; Research; Reserpine

1964
[EXPERIMENTAL STUDIES ON THE EFFECT OF SOME PHARMACOLOGICAL PREPARATIONS ON THE ANESTHETIC ACTIVITY OF COCAINE].
    Klinika oczna, 1964, Volume: 34

    Topics: Adjuvants, Anesthesia; Anesthetics; Anura; Caffeine; Chlorpromazine; Cocaine; Ephedrine; Epinephrine; Guinea Pigs; Humans; Nitrates; Pentylenetetrazole; Pharmacology; Phenobarbital; Rabbits; Research; Reserpine

1964
[SPASMO-DOLVIRAN OF THE "BAYER" LEVERKUSEN FIRM. TEST IN PRACTICE].
    Deutsches medizinisches Journal, 1964, Jun-20, Volume: 15

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Caffeine; Codeine; Drug Therapy; Gallbladder Diseases; Gastrointestinal Diseases; Hemorrhage; Muscle Relaxants, Central; Phenobarbital; Urologic Diseases

1964
TIME-SERIES, FREQUENCY ANALYSIS, AND ELECTROGENESIS OF THE EEGS OF NORMALS AND PSYCHOTICS BEFORE AND AFTER DRUGS.
    The American journal of psychiatry, 1965, Volume: 121

    Topics: Amphetamine; Antidepressive Agents; Barbiturates; Biomedical Research; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Deanol; Drug Therapy; Electroencephalography; Lysergic Acid Diethylamide; Meprobamate; Orphenadrine; Pentobarbital; Perphenazine; Pharmacology; Phenobarbital; Placebos; Schizophrenia; Statistics as Topic; Tranquilizing Agents

1965
An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.
    Journal of natural products, 2003, Volume: 66, Issue:10

    Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Caffeine; Cyclopentanes; Diazepam; Diterpenes; Dose-Response Relationship, Drug; Furans; Ginkgo biloba; Ginkgolides; Lactones; Male; Maze Learning; Mice; Mice, Inbred Strains; Molecular Structure; Motor Activity; Phenobarbital; Plant Extracts; Plants, Medicinal; Sleep

2003
[Migraine therapy with migraine kranit].
    Die Medizinische Welt, 1951, Sep-15, Volume: 20, Issue:37

    Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants, Central; Papaverine; Phenobarbital

1951
Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates.
    Pharmaceutical research, 2004, Volume: 21, Issue:8

    Topics: Administration, Cutaneous; Age Factors; Animals; Caffeine; Diffusion; Ear; Humans; In Vitro Techniques; Infant, Newborn; Infant, Premature; Iontophoresis; Lidocaine; Models, Animal; Permeability; Phenobarbital; Skin; Swine

2004
A comparison of Drosophila melanogaster detoxification gene induction responses for six insecticides, caffeine and phenobarbital.
    Insect biochemistry and molecular biology, 2006, Volume: 36, Issue:12

    Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Drosophila melanogaster; Drosophila Proteins; Enzyme Induction; Esterases; Gene Expression Profiling; Glutathione Transferase; Inactivation, Metabolic; Insecticides; Phenobarbital

2006
Functional analysis of the cis-acting elements responsible for the induction of the Cyp6a8 and Cyp6g1 genes of Drosophila melanogaster by DDT, phenobarbital and caffeine.
    Insect molecular biology, 2010, Volume: 19, Issue:1

    Topics: Animals; Caffeine; Cell Line; Cytochrome P-450 Enzyme System; DDT; Drosophila melanogaster; Drosophila Proteins; Drug Synergism; Gene Expression Regulation; Insecticide Resistance; Luciferases; Phenobarbital; Regulatory Elements, Transcriptional; Sequence Analysis, DNA; Xenobiotics

2010
Striking differences in proconvulsant-induced alterations of seizure threshold in two rat models.
    Neurotoxicology, 2012, Volume: 33, Issue:1

    Topics: Animals; Anticonvulsants; Caffeine; Central Nervous System Stimulants; Chlorpromazine; Convulsants; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Male; Pentylenetetrazole; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Reaction Time; Seizures; Theophylline; Time Factors; Tramadol

2012
Cardiac ryanodine receptor: Selectivity for alkaline earth metal cations points to the EF-hand nature of luminal binding sites.
    Bioelectrochemistry (Amsterdam, Netherlands), 2016, Volume: 109

    Topics: Amino Acid Sequence; Animals; Anticonvulsants; Barium; Binding Sites; Caffeine; Calcium; Cations, Divalent; Central Nervous System Stimulants; EF Hand Motifs; Humans; Magnesium; Metals, Alkaline Earth; Molecular Sequence Data; Myocardium; Phenobarbital; Ryanodine Receptor Calcium Release Channel; Sequence Alignment; Strontium

2016
Caffeine Protects Against Anticonvulsant-Induced Neurotoxicity in the Developing Rat Brain.
    Neurotoxicity research, 2017, Volume: 32, Issue:3

    Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Caffeine; Cytokines; gamma-Aminobutyric Acid; Gene Expression; Nerve Degeneration; Neuroprotective Agents; Phenobarbital; Random Allocation; Rats, Wistar; Receptors, Purinergic P1; Time Factors

2017
Caffeine Protects Against Anticonvulsant-Induced Impaired Neurogenesis in the Developing Rat Brain.
    Neurotoxicity research, 2018, Volume: 34, Issue:2

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Brain; Brain-Derived Neurotrophic Factor; Caffeine; Cell Proliferation; DNA-Binding Proteins; Doublecortin Protein; Female; Gene Expression Regulation, Developmental; Hypoxanthine Phosphoribosyltransferase; Male; Nerve Growth Factor; Nerve Tissue Proteins; Neurogenesis; Neurons; Neuroprotective Agents; Neurotrophin 3; PAX6 Transcription Factor; Phenobarbital; Rats; Rats, Wistar; RNA, Messenger; Time Factors

2018
Fabrication and Validation of Gyro-Dot-Optomotor Response Device using Gold Fish to Study Drugs Affecting Visual Perception.
    Indian journal of physiology and pharmacology, 2016, Volume: 60, Issue:2

    Topics: Animals; Caffeine; Color Perception; Drug Evaluation, Preclinical; Equipment Design; Ethambutol; Eye; Female; Goldfish; Image Processing, Computer-Assisted; Locomotion; Male; Phenobarbital; Photic Stimulation; Reproducibility of Results; Toxicity Tests; Visual Perception

2016
Caffeine intoxication: Behavioral and electrocorticographic patterns in Wistar rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 170

    Topics: Animals; Anticonvulsants; Caffeine; Diazepam; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures

2022
Urgent first-step screening method for ketamine, phenobarbital, zopiclone, zolpidem, phenytoin and thiopental in adulterated soft drink.
    Pakistan journal of pharmaceutical sciences, 2023, Volume: 36, Issue:5

    Topics: Caffeine; Carbonated Beverages; Female; Humans; Ketamine; Phenobarbital; Phenytoin; Reproducibility of Results; Thiopental; Zolpidem

2023