phenobarbital has been researched along with caffeine in 187 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 129 (68.98) | 18.7374 |
1990's | 19 (10.16) | 18.2507 |
2000's | 22 (11.76) | 29.6817 |
2010's | 14 (7.49) | 24.3611 |
2020's | 3 (1.60) | 2.80 |
Authors | Studies |
---|---|
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
Duffy, EM; Jorgensen, WL | 1 |
Topliss, JG; Yoshida, F | 1 |
Carrupt, PA; Martel, S; Ottaviani, G | 2 |
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
Glen, RC; Lowe, R; Mitchell, JB | 1 |
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
Sen, S; Sinha, N | 1 |
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Chłoń-Rzepa, G; Dąbrowska, M; Jankowska, A; Komsta, Ł; Pawłowski, M; Ślusarczyk, M; Starek, M; Zagórska, A | 1 |
Asai, S; Kubodera, T; Nadai, T; Tatematsu, A; Yoshizumi, H | 1 |
File, SE; Hyde, JR | 1 |
Hanson, HM; Ivester, CA; Morton, BR | 1 |
Pasricha, JS | 1 |
Adamkov, J; Bevilaqua, L; Drobný, M; Fundárek, J; Knéslová, L; Pithová, B; Wolfová, E | 1 |
Brown, L; Horning, MG; Kellaway, P; Lertratanangkoon, K; Nowlin, J; Zion, TE | 1 |
DeAngelis, RL; Hsu, SY; Welch, RM | 1 |
Abakumova, OIu; Kutsenko, NG; Lerman, MI; Podobed, OV | 1 |
Gan, IE; Schier, GM | 1 |
Boone, DL; Copeland, RF; Duggans, CF; Floyd-Jones, T; Kuo, WN; Smith, SO; Williams, JL | 1 |
Gourevitch, A; Yanev, S | 1 |
Pleshkova, NM; Shestakov, VV; Shutov, AA | 1 |
Bennett, EL; Flood, JF; Jarvik, ME; Orme, AE; Rosenzweig, MR | 1 |
Kaneko, M; Kaneko, Y; Kumashiro, H; Takahashi, Y | 1 |
Jenssen, D; Ramel, C | 1 |
Lefkowitz, SS; Nemeth, D | 1 |
Cravey, RH; Turner, JE | 1 |
Panikarskiĭ, VG | 1 |
Aldridge, A; Neims, AH; Parsons, WD | 1 |
Pozdniakov, VS | 1 |
Butler, CM; Hill, RM; Horning, MG; Howlin, J | 1 |
Aeschbacher, HU; Atkinson, J; Domahidy, B | 1 |
Borisenko, SA; Burov, IuV | 1 |
Butler, CM; Hill, RM; Horning, MG; Lertratanangkoon, K; Nowlin, J; Sommer, K | 1 |
Aeschbacher, HU | 1 |
Waldeck, B | 1 |
Hill, RM; Horning, MG; Sommer, KR | 1 |
Chiang, CY; Lefkowitz, SS | 1 |
Johnson, GF; Least, CJ; Solomon, HM | 1 |
Autret, E; Laugier, J; Nasr, C; Saliba, E; Suc, AL | 1 |
Ishikawa, A; Kobayashi, S; Misawa, S; Tanaka, E; Uchida, E; Yamamoto, Y; Yasuhara, H | 1 |
Billion-Rey, F; Brazier, JL; Guilluy, R | 1 |
Shestakov, VV; Shutov, AA | 1 |
Haginaka, J; Kimura, Y; Wakai, J; Yasuda, H | 1 |
Hasegawa, T | 1 |
Gong, HL; Wang, GF; Wu, YT | 1 |
Berthou, F; Dreano, Y; Guillouzo, A; Mondine, P; Ratanasavanh, D; Riche, C | 1 |
Kalhorn, TF; Lee, CA; Nelson, SD; Slattery, JT | 1 |
Dĕdic, K; Horácek, J | 1 |
Baty, C; Jambou, J; Leducq, B; Richard, L | 1 |
al-Chalabi, KA; al-Khayat, B; Ziz, LA | 1 |
Clerc, JT; Kosmeas, N | 1 |
Gomez, J; Rodriguez, A | 1 |
Devenyi, P; Rideout, J; Schneiderman, J | 1 |
Budka, I; Fikr, V; Stika, L | 1 |
Wu, Q; Yang, JY | 1 |
Brazier, JL; Cherrah, Y; Desage, M; Falconnet, JB; Tillement, JP; Zini, R | 1 |
Govindwar, SP; Kachole, MS; Pawar, SS | 1 |
Bauer, M; Bauerová, J; Bojar, Z; Dobrotka, G; Marsinová, G | 1 |
Broly, F; Carpentier, C; Houdret, N; Lequien, P; Lhermitte, M; Roussel, P; Zaoui, C | 1 |
Abbruzzi, R; Bastone, A; Bianchi, M; Bonati, M; Catalani, P; Guaitani, A; Latini, R; Pantarotto, C; Szczawinska, K | 1 |
Ortweiler, W; Peiker, G; Siegert, C; Splinter, FK; Traeger, A | 1 |
Kusenbach, G; Reinhardt, D | 1 |
Mendez-Alvarez, E; Sierra-Marcuño, G; Soto-Otero, R | 1 |
Benkö, A | 1 |
Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ | 1 |
Giurgea, CE; Moyersoons, FE | 1 |
Beyrich, T; Schleuder, M | 1 |
Koch, H | 1 |
Frank, GB; Jhamandas, K | 1 |
Lombrozo, L; Mitoma, C | 1 |
Izquierdo, I | 1 |
Falk, M; Fürst, W | 1 |
Smith, RL; Timbrell, JA | 1 |
Riethe, P; Wilske, E | 1 |
Doenicke, A; Konrad, T; Kugler, J; Laub, M; Wittmann, R | 1 |
Mancuso, G; Priolisi, A; Ziino, L | 1 |
Monnat, A | 1 |
Cornish, HH; Khanna, KL | 1 |
Hill, RM; Horning, MG; Lertratanangkoon, K; Nowlin, J; Stillwell, RN; Stillwell, WG | 1 |
Kammerl, E; Schlemmer, W | 1 |
Harvey, DJ; Hill, RM; Horning, MG; Nowlin, HJ; Stillwell, WG | 1 |
Panchenko, EN | 1 |
Basu, TK; Bishun, NP; Raven, RW; Williams, DC | 1 |
Cassell, WA; Hemingway, P | 1 |
Morikawa, M | 1 |
Boucher, EA; Horning, EC; Horning, MG; Stafford, M | 1 |
Kato, Y; Ouchi, T | 1 |
Marcus, RJ; Roberts, E; Simonsen, DG; Winters, WD | 1 |
Paschke, M; Schwanitz, F | 1 |
Hansch, C; Martin, YC | 1 |
Filipescu, A; Spirescu, J | 1 |
Rupollo, W | 2 |
Bapat, SK; Dhawn, BN; Saxena, VC | 1 |
Morrison, CF; Stephenson, JA | 1 |
Dehn, F; LeValley, SE; Lombrozo, L; Mitoma, C | 1 |
Eich, E; Geissler, H; Mutschler, E; Schunack, W | 1 |
Kiper, EM | 1 |
Breunig, HL; Broadlick, DE; Comer, JP; Sampson, CB | 1 |
Hess, R | 1 |
Gleiss, J | 1 |
Preibisch-Effenberger, R; Schmidt, V | 1 |
Burba, JV | 1 |
Burgison, RM; Dietz, AJ | 1 |
Barnett, HJ; Richards, RN | 1 |
Guillory, JK; Hwang, SC; Lach, JL | 1 |
Knothe, J; Preibischèffenberger, R | 1 |
Novotný, I; Vyskocil, F | 1 |
Wojnarowska, W | 1 |
Navrátil, K | 1 |
Blake, MI; Lin, SL | 1 |
Harrison, A; Neyraut-Sutterman, MT | 1 |
Anderson, SM; Daly, JW; Padgett, W; Weir, RL | 1 |
Drobný, M; Fundárek, J; Knéslová, L; Pithová, B | 1 |
Bukowskyj, M; Munt, PW; Nakatsu, K | 1 |
Chung, LW; Simpson, VJ | 1 |
Perlík, F | 1 |
Todorov, S | 1 |
Emley, GS; Hutchinson, RR | 1 |
Chessebeuf, M; Exilie-Frigere, MF; Padieu, P; Wood, G | 1 |
Arnaud, MJ; Bircher, J; Preisig, R; Voegelin, M; Wietholtz, H | 1 |
Hirshkowitz, M; Karacan, I; Thornby, JI | 1 |
Chaput de Saintonge, DM; Hong, CY; Turner, P | 1 |
Maier-Lenz, H; Ringwelski, L; Windorfer, A | 1 |
Angioi, RM; Bonetti, EP; Cumin, R; Haefely, WE; Möhler, H; Pieri, L; Polc, P | 1 |
Brazier, JL; Desage, M; Renaud, H; Ribon, B; Salle, B | 1 |
Czok, G; Finke, A | 1 |
Czok, G | 1 |
Bracken, W; Bullock, P; Draper, A; Parkinson, A; Pearce, R; Podval, J; Thomas, P; Veltman, J | 1 |
Balansky, RM; Blagoeva, PM; De Flora, S; Mircheva, ZI | 1 |
Kaa, E | 1 |
Jaw, S; Jeffery, EH | 1 |
Borowicz, K; Buszewicz, G; Czuczwar, SJ; Gasior, M; Kleinrok, Z | 1 |
Batzias, J; Horbach, GJ; Maas, RF; van Miert, AS; Witkamp, RF; Zweers-Zeilmaker, WM | 1 |
Shapovalov, VV; Shapovalova, VO | 1 |
Fujita, S; Funae, Y; Imaoka, S; Kazusaka, A; Maeda, Y; Masuda, M; Morita, K | 1 |
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM | 1 |
Chakrabarti, SK; Karas, M | 1 |
De Vivo, DC; Fischbarg, J; Ho, YY; Klepper, J; Wang, D; Yang, H | 1 |
Burgos, JS; Frizzo, ME; Lara, DR; Ramírez, G; Schmidt, AP; Souza, DO | 1 |
Agbaba, D; Aleksic, M; Eric, S; Franeta, JT; Pavkov, S; Vladimirov, S | 1 |
Fang, HH; Wen, L | 1 |
Gordon, N; Newton, RW | 1 |
HIGUCHI, T; LACH, JL | 1 |
LUSTIG, B | 1 |
BABES, A; PARHON, CI; PETREA, I | 1 |
LOLOVA, Kh; STOIMENOV, I | 1 |
AVRAMOV, NR | 1 |
ULMER, F | 1 |
SARSUNOVA, M; SCHWARZ, V | 1 |
SERVERDUPUY, JM | 1 |
EYSOLD, R | 1 |
WINBERG, J | 1 |
POPEK, K | 1 |
SENNE, W | 1 |
REMEZOVA, ES; SAFONOVA, SA | 1 |
MONCKTON, G | 1 |
BESSIN, P; BOISSIER, JR; DUMONT, C | 1 |
TEUCHMANN, JK; WIGLUSZ, Z | 1 |
WANSEL, H | 1 |
GOLDSTEIN, L; MURPHREE, HB; PFEIFFER, CC; SUGERMAN, AA | 1 |
Kuribara, H; Maruyama, Y; Weintraub, ST; Yoshihama, T | 1 |
KRISCHEK, J | 1 |
Guy, RH; Kalia, YN; Sekkat, N | 1 |
Batterham, P; Chung, H; Daborn, PJ; Lumb, C; Robin, C; Willoughby, L | 1 |
Błaszczyk, B; Chrościńska-Krawczyk, M; Czuczwar, SJ; Jankiewicz, K | 1 |
Ganguly, R; Kuruganti, S; Lam, V; Lucchesi, JC; Morra, R | 1 |
Bankstahl, JP; Bankstahl, M; Bloms-Funke, P; Löscher, W | 1 |
Gaburjakova, J; Gaburjakova, M | 1 |
Bendix, I; Bührer, C; Endesfelder, S; Schiller, C; Sifringer, M; Weichelt, U | 1 |
Bührer, C; Endesfelder, S; Schiller, C; von Haefen, C; Weichelt, U; Winter, K | 1 |
Ahmed, W; Biswas, NR; Halder, N; Menon, V; Saxena, R; Velpandian, T; Vijayakumar, AR | 1 |
Araújo, DB; Azevedo, JEC; Barbas, LAL; da Silva, ALM; Hamoy, AO; Hamoy, M; Lopes, DCF; Lopez, MEC; Mello, VJ; Nascimento, CP; Pereira, RG; Rodrigues, SF; Vieira, LR | 1 |
Anilanmert, B; Caglar-Andac, S; Narin, I | 1 |
5 review(s) available for phenobarbital and caffeine
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug metabolism in the human neonate.
Topics: Adult; Animals; Barbiturates; Caffeine; Epoxy Compounds; Female; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Maternal-Fetal Exchange; Meperidine; Milk; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Placenta; Pregnancy; Time Factors | 1975 |
Theophylline reassessed.
Topics: Acidosis; Aging; Allopurinol; Animals; Anti-Bacterial Agents; Breast Feeding; Bronchodilator Agents; Caffeine; Contraceptives, Oral; Cooking; Cystic Fibrosis; Drug Interactions; Erythromycin; Female; Heart Diseases; Histamine H2 Antagonists; Humans; Hypoxia; Infections; Kinetics; Liver Diseases; Lung Diseases, Obstructive; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Respiration Disorders; Sleep; Smoking; Theophylline | 1984 |
Glucose transporter type1 (GLUT-1) deficiency.
Topics: Anticonvulsants; Antioxidants; Ascorbic Acid; Blood-Brain Barrier; Caffeine; Central Nervous System Stimulants; Chromosomes, Human, Pair 1; Glucose; Glucose Transporter Type 1; Humans; Ketosis; Learning Disabilities; Monosaccharide Transport Proteins; Mutation; Phenobarbital; Seizures; Thioctic Acid | 2003 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
6 trial(s) available for phenobarbital and caffeine
Article | Year |
---|---|
[Effectiveness of fenalgin SPOFA in lumboischiadic syndrome (author's transl)].
Topics: Acetaminophen; Adult; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; Middle Aged; Phenobarbital; Sciatica; Syndrome | 1979 |
[Analgetic effects on the stimulus threshold of the human tooth].
Topics: Administration, Oral; Amides; Analgesics; Analysis of Variance; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Differential Threshold; Drug Evaluation; Electric Stimulation; Fumarates; Humans; Pain; Phenacetin; Phenobarbital; Piperidines; Placebos; Propionates; Pyridines; Toothache | 1974 |
[Electroencephalographic determination of vigilance following DL-propiramfumarate].
Topics: Amides; Analgesics; Aspirin; Attention; Caffeine; Clinical Trials as Topic; Codeine; Drug Synergism; Electroencephalography; Electrooculography; Ethanol; Eye Movements; Female; Fumarates; Humans; Male; Phenacetin; Phenobarbital; Piperidines; Placebos; Promethazine; Propionates; Pyridines | 1974 |
Effect of four centrally acting drugs on handwriting.
Topics: Caffeine; Chlorpromazine; Female; Handwriting; Humans; Male; Methamphetamine; Phenobarbital; Placebos | 1969 |
[DP-Neuralgen. Clinical trials in patients with the radicular syndrome].
Topics: Adult; Analgesics; Aspirin; Back Pain; Caffeine; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female; Humans; Intervertebral Disc Displacement; Male; Middle Aged; Phenacetin; Phenobarbital | 1983 |
[Clinical evaluation of analgesics].
Topics: Adult; Aged; Analgesics; Antipyrine; Aspirin; Caffeine; Clinical Trials as Topic; Codeine; Drug Combinations; Female; Humans; Male; Middle Aged; Osteoarthritis; Pain; Phenobarbital | 1984 |
176 other study(ies) available for phenobarbital and caffeine
Article | Year |
---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Prediction of drug solubility from Monte Carlo simulations.
Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility | 2000 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability.
Topics: 1-Octanol; Diffusion; Dimethylpolysiloxanes; Humans; In Vitro Techniques; Membranes, Artificial; Myristates; Permeability; Skin; Skin Absorption; Water | 2006 |
In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities.
Topics: Humans; Membranes, Artificial; Models, Biological; Models, Molecular; Octanols; Permeability; Pharmaceutical Preparations; Skin Absorption; Water | 2007 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Estimation of the lipophilicity of purine-2,6-dione-based TRPA1 antagonists and PDE4/7 inhibitors with analgesic activity.
Topics: Analgesics; Benzeneacetamides; Cyclic Nucleotide Phosphodiesterases, Type 7; Hydrophobic and Hydrophilic Interactions; Molecular Structure; Phenylbutyrates; Phosphodiesterase 4 Inhibitors; Principal Component Analysis; Quantitative Structure-Activity Relationship; TRPA1 Cation Channel; Xanthines | 2021 |
Mass spectrometry of medicines. Quantitative determination by direct probe inlet system mass chromatography.
Topics: Aspirin; Barbital; Barbiturates; Caffeine; Mass Spectrometry; Pharmaceutical Preparations; Phenacetin; Phenobarbital; Phenytoin | 1978 |
A test of anxiety that distinguishes between the actions of benzodiazepines and those of other minor tranquilisers and of stimulants.
Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anxiety; Caffeine; Central Nervous System Stimulants; Flurazepam; Humans; Interpersonal Relations; Meprobamate; Motor Activity; Phenobarbital; Rats; Social Behavior | 1979 |
Nicotine self-administration in rats.
Topics: Amphetamine; Animals; Caffeine; Chlordiazepoxide; Chlorpromazine; Drug Interactions; Drug Tolerance; Ethanol; Humans; Male; Mecamylamine; Nicotine; Pentolinium Tartrate; Phenobarbital; Phenytoin; Rats; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 1979 |
Drugs causing fixed eruptions.
Topics: Antipyrine; Caffeine; Cross Reactions; Drug Combinations; Drug Eruptions; Humans; Penicillin G; Phenacetin; Phenobarbital; Pyridones; Sulfadiazine; Sulfanilamides; Tetracycline | 1979 |
Use of saliva in therapeutic drug monitoring.
Topics: Antipyrine; Caffeine; Ethosuximide; Gas Chromatography-Mass Spectrometry; Humans; Immunoenzyme Techniques; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Primidone; Saliva; Theophylline | 1977 |
Effect of Aroclor 1254, phenobarbital, and polycyclic aromatic hydrocarbons on the plasma clearance of caffeine in the rat.
Topics: Animals; Aroclors; Caffeine; Chromatography, Thin Layer; Drug Interactions; Enzyme Induction; Liver; Male; Metabolic Clearance Rate; Phenobarbital; Polychlorinated Biphenyls; Polycyclic Compounds; Rats | 1977 |
[Accelerated microsomal DNA synthesis under the influence of xenobiotics and chemical carcinogens].
Topics: Animals; Benzopyrenes; Caffeine; Cell Nucleus; Cycloheximide; DNA; DNA, Mitochondrial; DNA, Neoplasm; Hydroxyurea; Liver Neoplasms, Experimental; Male; Methylnitrosourea; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital; Puromycin; Stimulation, Chemical | 1979 |
Interference of theophylline and caffeine in the gas-chromatographic estimation of phenobarbital.
Topics: Caffeine; Chromatography, Gas; Humans; Phenobarbital; Theophylline | 1979 |
Changes in the activities of protein kinase modulators in the cerebellum of mice due to ethanol, caffeine, or phenobarbital administration.
Topics: Animals; Ascorbic Acid; Caffeine; Cerebellum; Enzyme Activation; Ethanol; Kinetics; Mice; Nerve Tissue Proteins; Phenobarbital; Protein Kinases | 1979 |
Motor estimation of short time intervals under the effect of some psychotropic drugs.
Topics: Adult; Amphetamine; Caffeine; Chlorpromazine; Diazepam; Humans; Phenobarbital; Psychotropic Drugs; Reaction Time; Task Performance and Analysis; Time Perception | 1979 |
[Disorders of cerebral hemodynamics and their correction in epilepsy].
Topics: Brain Ischemia; Caffeine; Cerebrovascular Circulation; Epilepsy; Humans; Papaverine; Phenobarbital | 1979 |
Memory: modification of anisomycin-induced amnesia by stimulants and depressants.
Topics: Animals; Anisomycin; Avoidance Learning; Brain; Caffeine; Chloral Hydrate; Drug Interactions; Male; Memory; Mice; Nerve Tissue Proteins; Nicotine; Phenobarbital; Pyrrolidines | 1978 |
Therapeutic usefulness of ergotamine tartrate for narcolepsy.
Topics: Adult; Caffeine; Drug Combinations; Ergotamine; Humans; Male; Narcolepsy; Phenobarbital | 1978 |
Factors affecting the induction of micronuclei at low doses of X-rays, MMS and dimethylnitrosamine in mouse erythroblasts.
Topics: Animals; Caffeine; Cell Cycle; Cell Nucleus; Chromosome Aberrations; Dimethylnitrosamine; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Erythroblasts; Erythrocytes; Male; Methyl Methanesulfonate; Mice; Mice, Inbred CBA; Mutagens; Phenobarbital; X-Rays | 1978 |
Immunosuppression of rosette-forming cells.
Topics: Amphetamine; Animals; Body Weight; Caffeine; Erythrocytes; Humans; Immunity; Immunologic Techniques; Immunosuppression Therapy; Leukocytes; Male; Methadone; Mice; Morphine; Organ Size; Pentobarbital; Phenobarbital; Sheep; Spleen; Substance-Related Disorders | 1976 |
A fatal ingestion of caffeine.
Topics: Adult; Autopsy; Caffeine; Female; Humans; Phenobarbital | 1977 |
[Problems in treatment of autonomic disorders accompanying hypertensive disease].
Topics: Adult; Autonomic Nervous System; Benzimidazoles; Caffeine; Calcium; Female; Gluconates; Humans; Hypertension; Male; Nervous System Diseases; Papaverine; Phenobarbital | 1977 |
Stimulation of caffeine metabolism in the rat by 3-methylcholanthrene.
Topics: Animals; Caffeine; Kinetics; Male; Methylcholanthrene; Phenobarbital; Rats; Stimulation, Chemical; Time Factors | 1977 |
[An analysis of 22 years' experience with the medicinal treatment of epilepsy].
Topics: Adult; Anticonvulsants; Bromides; Caffeine; Codeine; Drug Therapy, Combination; Epilepsy; Female; History, 20th Century; Humans; Influenza, Human; Male; Middle Aged; Papaverine; Phenobarbital; Phytotherapy; Plants, Medicinal; Sodium; Tranquilizing Agents; Urea; USSR | 1975 |
The effect of caffeine on barbiturate sleeping time and brain level.
Topics: Aminopyrine N-Demethylase; Analysis of Variance; Animals; Barbiturates; Brain Chemistry; Caffeine; Drug Interactions; Hexobarbital; Liver; Male; Morphine Derivatives; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sleep; Time Factors | 1975 |
[The effect of psychotropic substances on the mental and physical work capacity of rats].
Topics: Amphetamine; Animals; Benactyzine; Caffeine; Chlordiazepoxide; Cocaine; Diazepam; Disability Evaluation; Electric Stimulation; Learning; Male; Meprobamate; Morphine; Phenobarbital; Psychotropic Drugs; Rats; Reinforcement, Psychology; Self Stimulation; Stimulation, Chemical; Work Capacity Evaluation | 1975 |
Clinical applications of gas chromatograph/mass spectrometer/computer systems.
Topics: Autoanalysis; Caffeine; Chromatography, Gas; Computers; Diazepam; Evaluation Studies as Topic; Female; Humans; Imides; Indicators and Reagents; Mass Spectrometry; Methods; Milk, Human; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Theobromine; Time Factors | 1975 |
Influence of methylxanthines on aniline disappearance and metabolism in rats.
Topics: Aniline Compounds; Aniline Hydroxylase; Animals; Caffeine; Coffee; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Proadifen; Rats; Tea; Theobromine; Xanthines | 1975 |
On the interaction between caffeine and barbiturates with respect to locomotor activity and brain catecholamines.
Topics: Animals; Brain; Caffeine; Clonidine; Dopamine; Drug Interactions; Female; Mice; Motor Activity; Norepinephrine; Pentobarbital; Phenobarbital; Piribedil; Reserpine | 1975 |
Identification and quantification of drugs in human amniotic fluid.
Topics: Amniotic Fluid; Caffeine; Chromatography, Gas; Computers; Female; Fetal Blood; Humans; Mass Spectrometry; Maternal-Fetal Exchange; Pharmaceutical Preparations; Phenobarbital; Pregnancy; Pregnancy Trimester, Third; Secobarbital; Theobromine | 1975 |
Effects of certain abused drug s on hemolysin forming cells.
Topics: Amphetamines; Animals; Antibody Formation; Antibody-Producing Cells; Ascorbic Acid; Aspirin; Caffeine; Hemolysin Proteins; Mice; Morphine; Nalorphine; Phenobarbital; Spleen | 1975 |
Gas-chromatographic micro-scale procedure for theophylline, with use of a nitrogen-sensitive detector.
Topics: Caffeine; Chromatography, Gas; Humans; Microchemistry; Nitrogen; Phenobarbital; Saliva; Theobromine; Theophylline; Xanthines | 1976 |
Perinatal pharmacology and cerebral blood flow.
Topics: Arteries; Blood Flow Velocity; Caffeine; Carbon Dioxide; Cerebrovascular Circulation; Drug Combinations; Fatty Alcohols; Humans; Indomethacin; Infant, Newborn; Partial Pressure; Phenobarbital; Phosphorylcholine; Polyethylene Glycols; Pulmonary Surfactants | 1992 |
A simplified approach for evaluation of hepatic drug-oxidizing activity with a simultaneous determination of caffeine and trimethadione and their demethylated metabolites in rats with a selective cytochrome P-450 inducer.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Humans; Liver; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Trimethadione | 1992 |
On-line measurements of 13C enrichments in rat breath. Non-invasive method for in vivo study of drug enzymatic induction.
Topics: Animals; Breath Tests; Caffeine; Carbon Dioxide; Carbon Isotopes; Cytochrome P-450 Enzyme System; Enzyme Induction; Gas Chromatography-Mass Spectrometry; Kinetics; Male; Methylcholanthrene; Phenobarbital; Rats | 1991 |
[Changes in cerebral blood circulation and their correction in the interparoxysmal period of epilepsy].
Topics: Adolescent; Adult; Brain Ischemia; Caffeine; Cerebrovascular Circulation; Drug Therapy, Combination; Epilepsy; Humans; Middle Aged; Papaverine; Phenobarbital; Regional Blood Flow | 1990 |
Determination of anticonvulsant drugs and methyl xanthine derivatives in serum by liquid chromatography with direct injection: column-switching method using a new internal-surface reversed-phase silica support as a precolumn.
Topics: Anticonvulsants; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Phenobarbital; Phenytoin; Primidone; Silicon Dioxide; Spectrophotometry, Ultraviolet; Theobromine; Theophylline; Xanthines | 1990 |
Depressive effects of lipid peroxides mediated via a purine receptor. Effect of lipid peroxide on the cortical synaptosomal GTPase activity.
Topics: Adenosine; Animals; Caffeine; Cerebral Cortex; Circadian Rhythm; Down-Regulation; GTP Phosphohydrolases; Lipid Peroxides; Locomotion; Mice; Phenobarbital; Rats; Receptors, Purinergic; Synaptosomes | 1990 |
[Application of convolution curve method for simultaneous determination of four components in somidon].
Topics: Aminopyrine; Analgesics; Caffeine; Drug Combinations; Methods; Phenacetin; Phenobarbital; Tablets | 1990 |
Methylcholanthrene but not phenobarbital enhances caffeine and theophylline metabolism in cultured adult human hepatocytes.
Topics: Adult; Biotransformation; Caffeine; Cells, Cultured; Humans; Kinetics; Liver; Methylcholanthrene; Phenobarbital; Theophylline | 1990 |
Effect of methylxanthines on acetaminophen hepatotoxicity in various induction states.
Topics: Acetaminophen; Alanine Transaminase; Animals; Benzoquinones; Body Temperature; Caffeine; Glutathione; Imines; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains; Theobromine; Theophylline | 1990 |
[Granulomatous processes in the lungs].
Topics: Acrylonitrile; Adult; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Granuloma; Humans; Lung Diseases; Male; Middle Aged; Occupational Diseases; Phenobarbital; Substance Abuse, Intravenous; Textile Industry | 1990 |
[Plasma determination of 7 common drugs by high performance liquid chromatography].
Topics: Anticonvulsants; Bronchodilator Agents; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Ethosuximide; Phenobarbital; Phenytoin; Theophylline; Valproic Acid | 1989 |
Presence and properties of cAMP phosphodiesterase from promastigote forms of Leishmania tropica and Leishmania donovani.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Calcium; Hydrogen-Ion Concentration; Kinetics; Leishmania donovani; Leishmania tropica; Magnesium; Phenobarbital; Substrate Specificity; Temperature; Theophylline; Trifluoperazine | 1989 |
[A quick DC method for simultaneous quantitative determination of paracetamol, caffeine, phenobarbital and propyphenazone in plasma].
Topics: Acetaminophen; Antipyrine; Caffeine; Humans; Phenobarbital | 1989 |
An evaluation of the results of a drug sample analysis.
Topics: Amphetamines; Caffeine; Cocaine; Drug Contamination; Heroin; Humans; Illicit Drugs; Lidocaine; Methaqualone; Phenobarbital; Procaine; Spain; Substance-Related Disorders | 1989 |
Abuse of a commonly prescribed analgesic preparation.
Topics: Adult; Analgesics, Opioid; Aspirin; Barbiturates; Caffeine; Codeine; Drug Combinations; Female; Humans; Inactivation, Metabolic; Male; Phenacetin; Phenobarbital; Substance-Related Disorders | 1985 |
[Possibilities of modelling of an undesirable phenomenon-- non-alcoholic substance abuse in society].
Topics: Adolescent; Adult; Alcohol Drinking; Aspirin; Caffeine; Child; Codeine; Czechoslovakia; Drug Combinations; Humans; Models, Theoretical; Phenobarbital; Socioeconomic Factors; Substance-Related Disorders | 1988 |
[Application of dynamic programming for quantitative analysis of qutong tablet and keganmin tablet].
Topics: Aminopyrine; Caffeine; Drug Combinations; Mathematics; Methods; Phenacetin; Phenobarbital; Tablets | 1988 |
Study of deutero-isotopomer-induced inhibition of caffeine and phenobarbitone binding to human serum albumin.
Topics: Binding Sites; Caffeine; Deuterium; Humans; Phenobarbital; Protein Binding; Serum Albumin | 1988 |
Effect of caffeine on the hepatic microsomal mixed function oxidase system during phenobarbital and benzo[a]pyrene treatment in rats.
Topics: Aminopyrine N-Demethylase; Animals; Benzo(a)pyrene; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1988 |
[Significance of the interaction between analgesic-antipyretics and ethanol in forensic medicine investigations].
Topics: Accidents, Traffic; Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Caffeine; Codeine; Drug Combinations; Drug Interactions; Ethanol; Forensic Medicine; Guaifenesin; Humans; Male; Middle Aged; Phenobarbital; Psychomotor Performance | 1987 |
Simultaneous administration of caffeine and phenobarbitone in infants with apnea.
Topics: Apnea; Caffeine; Drug Therapy, Combination; Half-Life; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Phenobarbital | 1987 |
Metabolism of caffeine to 6-amino-5-[N-methylformylamino]-1,3-dimethyluracil in the isolated, perfused liver from control or phenobarbital-, beta-naphthoflavone- and 3-methylcholanthrene-pretreated rats.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Caffeine; Chromatography, High Pressure Liquid; Drug Interactions; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Uracil | 1987 |
[The effect of intrahepatic cholestasis in pregnancy on various forms of cytochrome P-450-dependent biotransformation reactions].
Topics: Biotransformation; Caffeine; Cholestasis, Intrahepatic; Cytochrome P-450 Enzyme System; Female; Humans; Isoenzymes; Kinetics; Phenobarbital; Pregnancy; Pregnancy Complications | 1987 |
[Peculiarities of drug therapy in childhood].
Topics: Apnea; Biological Availability; Biotransformation; Caffeine; Child; Child, Preschool; Dexamethasone; Drug Therapy; Ductus Arteriosus, Patent; Half-Life; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature, Diseases; Metabolic Clearance Rate; Pharmaceutical Preparations; Phenobarbital; Receptors, Drug; Theophylline; Tissue Distribution | 1986 |
High performance liquid chromatographic procedure for the simultaneous determination of theophylline, caffeine, and phenobarbital in neonates.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Infant, Newborn; Phenobarbital; Spectrophotometry, Ultraviolet; Theophylline | 1985 |
[Post-mortem toxicological analysis and comparison of concentrations of drugs in organs and bones].
Topics: Amobarbital; Autopsy; Bone and Bones; Caffeine; Gas Chromatography-Mass Spectrometry; Glutethimide; Humans; Phenacetin; Phenobarbital; Tissue Distribution | 1985 |
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium | 1973 |
On the pharmacology of cortical evoked potentials.
Topics: Acetamides; Animals; Caffeine; Cats; Cerebral Cortex; Chlordiazepoxide; Chlorpromazine; Corpus Callosum; Dextroamphetamine; Electric Stimulation; Evoked Potentials; Phenobarbital; Pyrrolidinones; Reflex, Monosynaptic; Sciatic Nerve; Stereotaxic Techniques; Synaptic Transmission; Thiopental | 1972 |
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine | 1974 |
[Germination and growth inhibitory effect of thalidomide and different analeptics on embryos of Lepidium sativum].
Topics: Aminobutyrates; Caffeine; Camphor; Carbonates; Central Nervous System Stimulants; Depression, Chemical; Ephedrine; Ethanolamines; Nikethamide; Nitrates; Pentylenetetrazole; Phenobarbital; Seeds; Sodium; Strychnine; Sympathomimetics; Thalidomide | 1969 |
Effects of drugs acting alone and in combination on the motor activity of intact mice.
Topics: Adjuvants, Anesthesia; Aminobutyrates; Animals; Bemegride; Caffeine; Central Nervous System; Central Nervous System Stimulants; Chlorpromazine; Diazepam; Diphenhydramine; Female; Glutamates; Hydroxybutyrates; Lactones; Meperidine; Meprobamate; Mice; Motor Activity; Nikethamide; Phenobarbital; Picrotoxin; Promethazine; Reflex; Scopolamine; Seizures; Strychnine; Tranquilizing Agents | 1970 |
Effect of caffeine on hepatic microsomal cytochrome P-450.
Topics: Acetanilides; Adrenalectomy; Animals; Anisoles; Caffeine; Cytochromes; Enzyme Induction; Hydrogen-Ion Concentration; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitriles; Nitrophenols; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry; Sulfites; Time Factors | 1970 |
Effect on pseudoconditioning of drugs with known central nervous activity.
Topics: Amobarbital; Animals; Avoidance Learning; Behavior, Animal; Caffeine; Cannabis; Chlorpromazine; Conditioning, Psychological; Depression, Chemical; Diazepam; Dibenzylchlorethamine; Female; Meprobamate; Pentylenetetrazole; Phenobarbital; Phenytoin; Picrotoxin; Rats; Stimulation, Chemical; Strychnine; Trimethadione | 1974 |
[Drug permeation through synthetic lipid membranes. Permeability of lecithin-collodium membranes for drugs and metabolites].
Topics: Buffers; Caffeine; Diffusion; Hexobarbital; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Models, Chemical; Papaverine; Phenobarbital; Phenytoin; Phosphatidylcholines; Quinine; Salicylates; Solutions; Time Factors | 1974 |
Factors affecting the metabolism of phenacetin. II. Effect of aspirin, caffeine, codeine, ethanol and phenobarbital on the metabolism of (acetyl-14C)-phenacetin in the rat.
Topics: Acetates; Administration, Oral; Animals; Aspirin; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Chromatography, Thin Layer; Codeine; Ethanol; Feces; Female; Phenacetin; Phenobarbital; Rats; Respiration; Time Factors | 1974 |
[Effect in vitro of some drugs on albumin-bilirubin binding].
Topics: Anti-Bacterial Agents; Benzoates; Bilirubin; Caffeine; Digitalis Glycosides; In Vitro Techniques; Phenobarbital; Protein Binding; Serum Albumin; Sulfadimethoxine | 1972 |
[Comparative study of Lyell's and Stevens-Johnson syndromes: etiologic role of drugs].
Topics: Adolescent; Adult; Aged; Aspirin; Caffeine; Child; Child, Preschool; Codeine; Female; Humans; Hydantoins; Infant; Infant, Newborn; Male; Middle Aged; Penicillins; Phenacetin; Phenobarbital; Phenolphthaleins; Phenylbutazone; Promethazine; Stevens-Johnson Syndrome; Sulfamethoxypyridazine; Vaccines | 1972 |
The effect of daily ingestion of caffeine on the microsomal enzymes of rat liver.
Topics: Acetanilides; Administration, Oral; Aminopyrine N-Demethylase; Animals; Caffeine; Cytochrome P-450 Enzyme System; Cytochromes; Drug Synergism; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical; Time Factors | 1973 |
Use of stable isotopes in measuring low concentrations of drugs and drug metabolites by GC-MS-COM procedures.
Topics: Amniotic Fluid; Barbiturates; Caffeine; Carbon Isotopes; Child; Chromatography, Gas; Colostrum; Computers; Fatty Acids; Female; Humans; Hypnotics and Sedatives; Infant, Newborn; Male; Mass Spectrometry; Maternal-Fetal Exchange; Methods; Microchemistry; Milk, Human; Phenobarbital; Phenytoin; Pregnancy | 1973 |
Application of quantitative thin-layer chromatography in drug assay and stability testing. Determination of codeine phosphate, noscapine, diphenhydramine hydrochloride, phenylephrine hydrochloride, caffeine, etofyllin, phenobarbital and thiamine hydrochlo
Topics: Autoanalysis; Caffeine; Chromatography, Thin Layer; Codeine; Diphenhydramine; Drug Combinations; Drug Stability; Methods; Noscapine; Pharmaceutical Preparations; Phenobarbital; Phenylephrine; Spectrum Analysis; Theophylline; Thiamine | 1973 |
The use of gass chromatography-mass spectrometry methods in perinatal pharmacology.
Topics: Barbiturates; Caffeine; Chromatography, Gas; Female; Fetus; Humans; Infant, Newborn; Mass Spectrometry; Maternal-Fetal Exchange; Meperidine; Phenobarbital; Pregnancy; Secobarbital | 1973 |
[Treatment of extrapyramidal hyperkinesis].
Topics: Adolescent; Adult; Ambulatory Care; Basal Ganglia Diseases; Benzimidazoles; Benzyl Compounds; Bromine; Caffeine; Chronic Disease; Drug Combinations; Humans; Hyperkinesis; Male; Middle Aged; Papaverine; Parasympatholytics; Phenobarbital; Powders; Urea; Valerates | 1973 |
Proceedings: Accentuation of chlorambucil effect by various additives on rat tumour cells in culture.
Topics: Animals; Caffeine; Cells, Cultured; Chlorambucil; Drug Synergism; Neoplasms, Experimental; Phenobarbital; Rats; Vitamin A | 1974 |
Body consciousness in states of pharmacological depression and arousal.
Topics: Arousal; Barbiturates; Caffeine; Consciousness; Female; Humans; Male; Perception; Phenobarbital; Projective Techniques; Psychopharmacology | 1970 |
[Effects of various drugs on metabolism of the skeletal muscle. 2. Effects of procaine, pentobarbital and phenobarbital on the stimulated respiration of the skeletal muscle].
Topics: Animals; Anura; Caffeine; Depression, Chemical; Dinitrophenols; Edetic Acid; In Vitro Techniques; Muscles; Ouabain; Oxygen Consumption; Pentobarbital; Phenobarbital; Potassium; Procaine; Ranidae; Stimulation, Chemical; Sucrose | 1971 |
A rapid procedure for the isolation of drugs and drug metabolites from plasma.
Topics: 1-Propanol; Animals; Caffeine; Carbon Isotopes; Carbonates; Chromatography, Gas; Chromatography, Thin Layer; Fatty Acids; Humans; Mass Spectrometry; Methods; Methylation; Phenobarbital; Potassium; Rats; Silicon | 1972 |
[Studies on solubilizing agents. IV. Dielectric constant correlations with drug solubility in the mixtures of glycols and their derivatives with water].
Topics: Caffeine; Glycols; Pharmaceutic Aids; Phenobarbital; Salicylates; Solubility; Solvents; Water | 1972 |
Neuropharmacological studies of imidazole-4-acetic acid actions in the mouse and rat.
Topics: Acetates; Animals; Ataxia; Behavior; Caffeine; Catalepsy; Central Nervous System; Drug Interactions; Drug Synergism; Electroencephalography; Humans; Hydroxybutyrates; Imidazoles; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Motor Activity; Pentylenetetrazole; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Sleep; Stimulation, Chemical; Strychnine; Time Factors | 1971 |
[Pretesting of drugs using lower and higher plants. II. Effect of phenazetin and various substances frequently combined with it, on the shape and growth of Micrasterias americana].
Topics: Antineoplastic Agents; Biological Assay; Caffeine; Cell Division; Cell Transformation, Neoplastic; Drug Synergism; Eukaryota; Phenacetin; Phenobarbital; Quinine | 1971 |
Influence of hydrophobic character on the relative rate of oxidation of drugs by rat liver microsomes.
Topics: Aniline Compounds; Animals; Barbiturates; Caffeine; Chemical Phenomena; Chemistry, Physical; Chlorine; Codeine; Ephedrine; Fatty Alcohols; Hexobarbital; Kinetics; Male; Mathematics; Microsomes, Liver; Mixed Function Oxygenases; Naphthalenes; Oxidoreductases; Phenobarbital; Physostigmine; Rats; Solubility; Structure-Activity Relationship | 1971 |
[The pain syndrome of the edentulous alveolar crest and its treatment].
Topics: Administration, Topical; Alveolar Process; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Caffeine; Chlorpromazine; Codeine; Humans; Hyaluronoglucosaminidase; Hydrocortisone; Mouth, Edentulous; Pain; Phenobarbital; Procaine; Promethazine | 1969 |
[Treatment of epilepsy with a combination of Gardenal and caffeine. Presentation of 84 cases].
Topics: Adolescent; Adult; Caffeine; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital | 1968 |
[Treatment of epilepsy using a combination of Gardenal and caffeine. Report of 84 cases].
Topics: Adolescent; Adult; Caffeine; Child; Epilepsy; Female; Humans; Male; Middle Aged; Phenobarbital | 1968 |
Nicotine injections as the conditioned stimulus in discrimination learning.
Topics: Amphetamine; Animals; Apomorphine; Caffeine; Chlordiazepoxide; Chlorisondamine; Conditioning, Operant; Discrimination Learning; Electroshock; Epinephrine; Gallamine Triethiodide; Male; Mecamylamine; Nicotine; Noise; Phenobarbital; Physostigmine; Rats; Water | 1969 |
Nature of the effect of caffeine on the drug-metabolizing enzymes.
Topics: 17-Hydroxycorticosteroids; Acetanilides; Amino Acids; Aminopyrine; Aniline Compounds; Animals; Caffeine; Cytochromes; Dactinomycin; Drug Antagonism; Enzyme Induction; Female; Humans; Male; Methylation; Microsomes, Liver; Oxidoreductases; Phenobarbital; Pregnanes; Pyridones; Rats; Stimulation, Chemical; Time Factors; Zoxazolamine | 1969 |
[Direct quantitative evaluation of thin layer chromatogramms by remission- and fluorescence measurement. 2. Determination of drugs in 2 combination preparations by remission measurements].
Topics: Amitriptyline; Aspirin; Caffeine; Capsules; Chlordiazepoxide; Chromatography, Thin Layer; Codeine; Phenacetin; Phenobarbital; Phosphates; Spectrophotometry; Tablets | 1969 |
[Quantitative determination of salicylamide, phenacetin, caffeine, diphenhydramine chlorhydrate, luminal combinations].
Topics: Caffeine; Diphenhydramine; Drug Combinations; Phenacetin; Phenobarbital; Salicylamides | 1969 |
Estimation of mean potency and content uniformity of tablets: a new approach.
Topics: Atropine; Caffeine; Chemistry, Pharmaceutical; Computers; Diethylstilbestrol; Drug Compounding; Drug Tolerance; Isoniazid; Mestranol; Methyltestosterone; Models, Theoretical; Paramethasone; Pharmaceutical Preparations; Phenobarbital; Sulfates; Tablets | 1970 |
[Therapy of epilepsy].
Topics: Amphetamine; Anticonvulsants; Caffeine; Child; Drug Synergism; Epilepsy; Humans; Hydantoins; Phenobarbital | 1967 |
[Further studies on the growth inhibitory effect of hypnotics in embryos of Sinapis alba].
Topics: Caffeine; Chloral Hydrate; Chlorophyll; Depression, Chemical; Embryo, Mammalian; Embryo, Nonmammalian; Female; Glutethimide; Mustard Plant; Phenobarbital; Plants, Medicinal; Pregnancy; Procaine; Thalidomide | 1967 |
[The influence of centrally acting drugs on directional hearing of normal subjects in a free acoustic field].
Topics: Aged; Audiometry; Auditory Perception; Benactyzine; Caffeine; Chlorpromazine; Female; Humans; Male; Meprobamate; Middle Aged; Phenobarbital; Strychnine | 1968 |
Influence of several drugs on the in vivo and in vitro activity of mammalian hepatic azo-reductase.
Topics: Animals; Caffeine; Guanethidine; Guinea Pigs; In Vitro Techniques; Iproniazid; Isoniazid; Liver; Nitrofurantoin; Oxidoreductases; Pentylenetetrazole; Phenobarbital; Phenylbutazone; Phenytoin; Rabbits; Rats; Sulfinpyrazone; Sulfonic Acids; Trimethadione | 1968 |
The hypnotic properties of 8-ethylthio-6-thiotheophylline sodium.
Topics: Amphetamine; Animals; Caffeine; Chloral Hydrate; Chlorpromazine; Dogs; Drug Synergism; Hexobarbital; Hypnotics and Sedatives; Male; Meprobamate; Methylphenidate; Mice; Morphine; Nalorphine; Nikethamide; Pentobarbital; Pentylenetetrazole; Phenobarbital; Rabbits; Rats; Reserpine; Sleep; Theophylline; Thiopental | 1968 |
Paroxysmal dystonic choreoathetosis. A family study and review of the literature.
Topics: Adult; Aged; Amobarbital; Athetosis; Atropine; Benzoates; Caffeine; Child, Preschool; Chorea; Coffee; Consciousness; Electroencephalography; Fatigue; Female; Functional Laterality; Humans; Male; Middle Aged; Motion Pictures; Muscles; Muscular Diseases; Neostigmine; Pedigree; Phenobarbital; Phenytoin; Phytotherapy; Stress, Physiological; Suggestion | 1968 |
Interactions between pharmaceutical compounds by thermal methods.
Topics: Acetaminophen; Aspirin; Atropine; Bile Acids and Salts; Caffeine; Drug Compounding; Drug Incompatibility; Drug Stability; Methods; Phenacetin; Phenobarbital; Phenytoin; Quinine; Temperature; Theophylline; Thermodynamics; Time Factors; Vitamin K | 1969 |
[The influence of centrally active drugs on sound perception in normally hearing subjects using a binaural speech test].
Topics: Benactyzine; Caffeine; Chlorpromazine; Hearing; Hearing Tests; Humans; Meprobamate; Phenobarbital; Psychopharmacology; Strychnine | 1965 |
Possible role of Ca ions in the resting metabolism of frog sartorius muscle during potassium depolarization.
Topics: Animals; Anura; Caffeine; Calcium; Calcium Chloride; Cell Membrane Permeability; Electrophysiology; In Vitro Techniques; Isotonic Solutions; Muscles; Oxygen Consumption; Phenobarbital; Physostigmine; Potassium; Procaine | 1966 |
Influence exerted on auditory fatigue by some calmatives and stimulants of the central nervous system.
Topics: Adolescent; Adult; Audiometry; Caffeine; Fatigue; Female; Hearing; Humans; Lobeline; Male; Meprobamate; Middle Aged; Phenobarbital; Reticular Formation; Strychnine; Tranquilizing Agents | 1966 |
[New drugs. Premenstrin. (Tablets)].
Topics: Caffeine; Ergotamine; Female; Guaifenesin; Phenobarbital; Premenstrual Syndrome; Tablets | 1966 |
Determination of acetylsalicylic acid and barbiturate combinations in dosage forms.
Topics: Amobarbital; Aspirin; Atropa belladonna; Barbiturates; Caffeine; Dextroamphetamine; Dosage Forms; Phenacetin; Phenobarbital; Plants, Medicinal; Plants, Toxic; Potentiometry | 1967 |
[EEG studies of cases with epileptic and intricate somatic manifestations].
Topics: Adult; Asthma; Atropa belladonna; Caffeine; Child; Drug Tolerance; Eczema; Electroencephalography; Epilepsy; Humans; Hypersensitivity; Male; Migraine Disorders; Phenobarbital; Phytotherapy; Plants, Medicinal; Plants, Toxic | 1967 |
Interaction of anticonvulsant drugs with adenosine receptors in the central nervous system.
Topics: Adenosine; Animals; Anticonvulsants; Brain; Caffeine; Carbamazepine; Cerebellum; Cerebral Cortex; Cyclic AMP; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic; Theophylline | 1984 |
Programming of rat hepatic arylhydrocarbon hydroxylase activity during late neonatal period.
Topics: Animals; Animals, Newborn; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzopyrenes; Caffeine; DNA; Female; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains | 1982 |
[Relationship between the placental-fetal index (PFI) and the toxic and teratogenic effect in the fetuses of mothers treated with sedalgin during pregnancy].
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Caffeine; Codeine; Drug Combinations; Female; Fetus; Phenacetin; Phenobarbital; Placenta; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Time Factors | 1983 |
Unique influences of ten drugs upon post-shock biting attack and pre-shock manual responding.
Topics: Aggression; Animals; Bites and Stings; Caffeine; Chlordiazepoxide; Chlorpromazine; Cocaine; Conditioning, Operant; Dextroamphetamine; Diazepam; Electroshock; Ethanol; Female; Humans; Male; Morphine; Nicotine; Phenobarbital; Saimiri | 1983 |
Interactions of caffeine and phenobarbital on sister chromatid exchanges in rat liver epithelial cell lines treated with 2-acetyl-aminofluorene and N-acetoxy-2-acetylaminofluorene.
Topics: 2-Acetylaminofluorene; Acetoxyacetylaminofluorene; Animals; Caffeine; Cell Line; Cells, Cultured; Crossing Over, Genetic; Epithelial Cells; Epithelium; Liver; Metaphase; Phenobarbital; Rats; Sister Chromatid Exchange | 1984 |
Assessment of the cytochrome P-448 dependent liver enzyme system by a caffeine breath test.
Topics: Adult; Animals; Breath Tests; Caffeine; Carbon Dioxide; Carbon Radioisotopes; Cytochrome P-450 CYP1A2; Cytochromes; Dealkylation; Enzyme Induction; Humans; Liver; Liver Cirrhosis; Male; Methylcholanthrene; Middle Aged; Phenobarbital; Rats; Rats, Inbred Strains; Tobacco Use Disorder | 1981 |
Sleep spindles: pharmacological effects in humans.
Topics: Atropine; Azepines; Caffeine; Cerebral Cortex; Computers; Dose-Response Relationship, Drug; Double-Blind Method; Electroencephalography; Evoked Potentials; Flurazepam; Haloperidol; Humans; N-Methylscopolamine; Phenobarbital; Scopolamine; Scopolamine Derivatives; Sleep Stages; Thalidomide; Tryptophan | 1982 |
Effects of chlorpromazine and other drugs acting on the central nervous system on human sperm motility.
Topics: Caffeine; Central Nervous System; Chlorpromazine; Diazepam; Humans; In Vitro Techniques; Male; Phenobarbital; Phenytoin; Sperm Motility | 1982 |
[A comparative pharmacokinetic study for tablet and suppository formulations of a combination product of caffeine, ethaverine, propyphenazone, paracetamol and phenobarbital (author's transl)].
Topics: Acetaminophen; Adult; Analgesics; Antipyrine; Caffeine; Drug Combinations; Humans; Kinetics; Male; Papaverine; Phenobarbital; Rectum; Suppositories; Tablets | 1981 |
Caffeine antagonizes several central effects of diazepam.
Topics: Aggression; Animals; Caffeine; Cats; Central Nervous System; Conflict, Psychological; Diazepam; Humans; Hypothalamus; Muscle Tonus; Pentylenetetrazole; Phenobarbital; Spinal Cord | 1981 |
In vivo N7 methylation of theophylline to caffeine in premature infants. Studies with use of stable isotopes.
Topics: Caffeine; Carbon Isotopes; Humans; Infant, Newborn; Infant, Premature; Methylation; Nitrogen Isotopes; Phenobarbital; Theophylline; Time Factors | 1981 |
[Modification of the caffeine metabolism in mouse liver slices by previous treatment of the experimental animals with ethanol, aminophenazone and phenobarbital].
Topics: Aminopyrine; Animals; Caffeine; Dose-Response Relationship, Drug; Ethanol; In Vitro Techniques; Liver; Male; Mice; Phenobarbital; Rats; Species Specificity | 1980 |
[Reciprocal action between caffeine, other stimulants and drugs].
Topics: Analgesics; Animals; Barbiturates; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Humans; Methylcholanthrene; Nicotinic Acids; Phenobarbital; Smoking; Theobromine; Xanthines | 1980 |
Induction of liver microsomal cytochrome P450 in cynomolgus monkeys.
Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Blotting, Western; Caffeine; Coumarins; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochromes b5; Dexamethasone; Enzyme Induction; Female; Hydroxylation; Isoenzymes; Macaca fascicularis; Male; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxazines; Oxidation-Reduction; Phenobarbital; Sex Factors; Species Specificity; Testosterone | 1995 |
Modulation of diethylnitrosamine carcinogenesis in rat liver and oesophagus.
Topics: Animals; Antineoplastic Agents; Antioxidants; Ascorbic Acid; Caffeine; Diethylnitrosamine; Disease Models, Animal; Esophageal Neoplasms; Female; Liver Neoplasms, Experimental; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred Strains; Survival; Theophylline; Tretinoin | 1994 |
Impurities, adulterants and diluents of illicit heroin. Changes during a 12-year period.
Topics: Acetaminophen; Caffeine; Carbohydrates; Denmark; Drug Contamination; Heroin; Hydrogen-Ion Concentration; Illicit Drugs; Lactose; Morphine; Noscapine; Papaverine; Phenobarbital; Procaine | 1994 |
Interaction of caffeine with acetaminophen. 1. Correlation of the effect of caffeine on acetaminophen hepatotoxicity and acetaminophen bioactivation following treatment of mice with various cytochrome P450 inducing agents.
Topics: Acetaminophen; Acetone; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Benzoquinones; beta-Naphthoflavone; Biotransformation; Caffeine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Activation; Female; Imines; Isoenzymes; Kinetics; Liver Diseases; Mice; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital | 1993 |
Anticonvulsant activity of phenobarbital and valproate against maximal electroshock in mice during chronic treatment with caffeine and caffeine discontinuation.
Topics: Animals; Anticonvulsants; Caffeine; Electroshock; Male; Mice; Phenobarbital; Seizures; Valproic Acid | 1996 |
In vitro and in vivo oxidative biotransformation in the West-African dwarf goat (Caprus hircus aegagrus): substrate activities and effects of inducers.
Topics: Animals; Antipyrine; beta-Naphthoflavone; Biotransformation; Blotting, Western; Caffeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Goats; Isoniazid; Microsomes, Liver; Phenobarbital; Sulfamethazine; Troleandomycin | 1996 |
[Spasmophilia in children and the anticonvulsant properties of a new Ukrainian preparation containing a pyrimidine derivative].
Topics: Animals; Anticonvulsants; Aspirin; Caffeine; Child; Convulsants; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation, Preclinical; Humans; Mice; Pentylenetetrazole; Phenobarbital; Tablets; Tetany | 1998 |
Strain differences in CYP3A-mediated C-8 hydroxylation (1,3,7-trimethyluric acid formation) of caffeine in Wistar and Dark Agouti rats. Rapid metabolism of caffeine in debrisoquine poor metabolizer model rats.
Topics: Aging; Animals; Aryl Hydrocarbon Hydroxylases; Caffeine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Debrisoquin; Dexamethasone; Female; Humans; Hydroxylation; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Sex Characteristics; Species Specificity; Troleandomycin; Uric Acid | 1998 |
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro.
Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics | 1999 |
Influence of caffeine on allyl alcohol-induced hepatotoxicity in rats. I. In vivo study.
Topics: Acrolein; Alanine Transaminase; Alcohol Dehydrogenase; Animals; Caffeine; Chemical and Drug Induced Liver Injury; Drug Interactions; Enzyme Inhibitors; Fomepizole; Glutathione; Hepatocytes; Liver; Male; Phenobarbital; Propanols; Pyrazoles; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 2001 |
Glucose transporter type 1 deficiency syndrome (Glut1DS): methylxanthines potentiate GLUT1 haploinsufficiency in vitro.
Topics: 3-O-Methylglucose; Adolescent; Caffeine; Case-Control Studies; Child; Erythrocytes; Female; Humans; In Vitro Techniques; Kinetics; Male; Monosaccharide Transport Proteins; Mutation; Phenobarbital; Syndrome; Theophylline | 2001 |
Effect of orally administered guanosine on seizures and death induced by glutamatergic agents.
Topics: Animals; Brain; Caffeine; Death; Dizocilpine Maleate; Dose-Response Relationship, Drug; Elapid Venoms; Epilepsy; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Guanosine; Kainic Acid; Male; Mice; Neuroprotective Agents; Phenobarbital; Phosphodiesterase Inhibitors; Quinolinic Acid; Receptors, Purinergic P1 | 2001 |
HPLC assay of acetylsalicylic acid, paracetamol, caffeine and phenobarbital in tablets.
Topics: Acetaminophen; Analgesics; Aspirin; Caffeine; Chromatography, High Pressure Liquid; Drug Combinations; Pharmaceutical Preparations; Phenobarbital; Reproducibility of Results; Tablets | 2002 |
[Simultaneous determination of four components in the compound child phenobarbital tablet using ultraviolet spectrophotometry].
Topics: Aspirin; Caffeine; Child; Child, Preschool; Drug Compounding; Humans; Infant; Phenacetin; Phenobarbital; Spectrophotometry, Ultraviolet; Tablets | 2002 |
Investigation of some complexes formed in solution by caffeine. IV. Interactions between caffeine and sulfathiazole, sulfadiazine, p-aminobenzoic acid, benzocaine, phenobarbital, and barbital.
Topics: 4-Aminobenzoic Acid; Aminobenzoates; Barbital; Barbiturates; Benzocaine; Caffeine; Pharmaceutical Solutions; Phenobarbital; Solutions; Sulfadiazine; Sulfathiazole; Sulfathiazoles | 1954 |
[Epilepsy therapy with the combination preparation centronal compositum].
Topics: Aminopyrine; Caffeine; Epilepsy; Humans; Hydantoins; Phenobarbital; Porphyrins | 1957 |
The action exercised by the thymus and several neurotropic substances in experimental cancer.
Topics: Animals; Benzoates; Caffeine; Humans; Neoplasms; Neoplasms, Experimental; Phenobarbital; Thymus Extracts | 1957 |
[Hypoglycemic coma induced by small doses of insulin in the treatment of psychiatric diseases; combination of insulin with luminal and caffeine. I].
Topics: Caffeine; Coma; Convulsive Therapy; Humans; Hypoglycemia; Hypoglycemic Agents; Insulin; Mental Disorders; Phenobarbital | 1957 |
[Studies on the effect of neurotropic substances caffeine-sodium benzoate, luminal sodium, acetylcholine and atropine on anti-anemic intrinsic factor].
Topics: Acetylcholine; Atropine; Benzoates; Caffeine; Drug Combinations; Gastric Juice; Humans; Intrinsic Factor; Phenobarbital; Sodium; Sodium Benzoate | 1960 |
[The modification of flicker fusion frequency in man by phenylpyrrolidinopentane, Katovit, caffeine and phenylethylbarbituric acid].
Topics: Ascorbic Acid; Caffeine; Flicker Fusion; Folic Acid; Humans; Male; Phenobarbital; Pyrrolidines; Sympathomimetics; Vitamin B Complex; Vitamins | 1961 |
[Some possibilities for the use of thin-layer chromatography without binding agents in drug analysis. 3. Qualitative detection of purines and barbiturates used in prescriptions].
Topics: Aminophylline; Barbiturates; Caffeine; Chromatography, Thin Layer; Phenobarbital; Purines; Substance Abuse Detection; Theobromine; Theophylline | 1963 |
[THE CUFF METHOD FOR THE ANTALGIC EVALUATION OF DIFFERENT DRUGS].
Topics: Aminopyrine; Arthritis; Arthritis, Rheumatoid; Aspirin; Caffeine; Gout; Osteoarthritis; Phenobarbital; Phenylbutazone; Prednisolone; Procaine; Sciatica; Tendinopathy | 1963 |
[GENESIS, CLASSIFICATION AND THERAPY OF LOSS OF CONSCIOUSNESS].
Topics: Caffeine; Child; Classification; Electroencephalography; Epilepsy; Epilepsy, Absence; Humans; Oxyphenbutazone; Phenobarbital; Phenytoin; Physiology; Pyrrolidinones; Unconsciousness | 1963 |
[ANALYSIS OF THE POSSIBLE RELATION OF FETAL DAMAGE AND DRUGS. V. PRELIMINARY STUDY ON THE INFLUENCE OF 4 ANTIEMETICS ON FETAL DEVELOPMENT].
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Abortion, Spontaneous; Antiemetics; Birth Weight; Caffeine; Ephedrine; Female; Fetal Death; Fetal Development; Humans; Infant; Infant, Newborn; Infant, Premature; Meclizine; Pharmacology; Phenobarbital; Pregnancy; Prochlorperazine; Promethazine | 1964 |
THE STUDY OF CHANGES IN THE SO-CALLED SUCCESSIVE CONTRAST IN NEUROLOGY.
Topics: Afterimage; Amphetamine; Arteriosclerosis; Brain Concussion; Brain Injuries; Brain Neoplasms; Bromides; Caffeine; Cerebrovascular Disorders; Goiter; Graves Disease; Humans; Lymph Nodes; Multiple Sclerosis; Neurasthenia; Neurology; Neurotic Disorders; Occupational Diseases; Optic Atrophy; Phenobarbital; Tetany; Tuberculosis; Tuberculosis, Lymph Node | 1964 |
[SPASMO-DOLVIRAN "BAYER" IN GENERAL PRACTICE].
Topics: Aspirin; Caffeine; Codeine; Colic; Family Practice; General Practice; Humans; Migraine Disorders; Phenacetin; Phenobarbital; Spasm | 1964 |
[TREATMENT OF PATIENTS WITH EPILEPSY WITH FREQUENT PETIT MAL SEIZURES].
Topics: Anticonvulsants; Caffeine; Drug Therapy; Epilepsy; Epilepsy, Absence; Humans; Phenobarbital; Seizures | 1964 |
DRUGS FOR HEADACHE OF MIGRAINOUS, VASCULAR OR MUSCULAR ORIGIN.
Topics: Aspirin; Caffeine; Cardiovascular Agents; Ergot Alkaloids; Ergotamine; Headache; Humans; Meprobamate; Methysergide; Migraine Disorders; Oxytocics; Pharmacology; Phenacetin; Phenobarbital; Scopolamine; Toxicology | 1964 |
[ON A NEW METHOD OF RECORDING MOVEMENT IN THE LABORATORY ANIMAL MAINTAINED IN ITS REARING ENVIRONMENT--ITS APPLICATION TO THE STUDY OF SOME BEHAVIOR-MODIFYING AGENTS].
Topics: Amphetamine; Amphetamines; Animals; Animals, Laboratory; Barbiturates; Behavior, Animal; Caffeine; Chlorpromazine; Cinnamates; Cyanides; Heterocyclic Compounds; Hypnotics and Sedatives; Injections, Intraperitoneal; Mice; Morphine; Movement; Pharmacology; Phenobarbital; Research; Reserpine | 1964 |
[EXPERIMENTAL STUDIES ON THE EFFECT OF SOME PHARMACOLOGICAL PREPARATIONS ON THE ANESTHETIC ACTIVITY OF COCAINE].
Topics: Adjuvants, Anesthesia; Anesthetics; Anura; Caffeine; Chlorpromazine; Cocaine; Ephedrine; Epinephrine; Guinea Pigs; Humans; Nitrates; Pentylenetetrazole; Pharmacology; Phenobarbital; Rabbits; Research; Reserpine | 1964 |
[SPASMO-DOLVIRAN OF THE "BAYER" LEVERKUSEN FIRM. TEST IN PRACTICE].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Caffeine; Codeine; Drug Therapy; Gallbladder Diseases; Gastrointestinal Diseases; Hemorrhage; Muscle Relaxants, Central; Phenobarbital; Urologic Diseases | 1964 |
TIME-SERIES, FREQUENCY ANALYSIS, AND ELECTROGENESIS OF THE EEGS OF NORMALS AND PSYCHOTICS BEFORE AND AFTER DRUGS.
Topics: Amphetamine; Antidepressive Agents; Barbiturates; Biomedical Research; Caffeine; Central Nervous System Stimulants; Chlordiazepoxide; Chlorpromazine; Deanol; Drug Therapy; Electroencephalography; Lysergic Acid Diethylamide; Meprobamate; Orphenadrine; Pentobarbital; Perphenazine; Pharmacology; Phenobarbital; Placebos; Schizophrenia; Statistics as Topic; Tranquilizing Agents | 1965 |
An anxiolytic-like effect of Ginkgo biloba extract and its constituent, ginkgolide-A, in mice.
Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Benzodiazepines; Caffeine; Cyclopentanes; Diazepam; Diterpenes; Dose-Response Relationship, Drug; Furans; Ginkgo biloba; Ginkgolides; Lactones; Male; Maze Learning; Mice; Mice, Inbred Strains; Molecular Structure; Motor Activity; Phenobarbital; Plant Extracts; Plants, Medicinal; Sleep | 2003 |
[Migraine therapy with migraine kranit].
Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants, Central; Papaverine; Phenobarbital | 1951 |
Porcine ear skin as a model for the assessment of transdermal drug delivery to premature neonates.
Topics: Administration, Cutaneous; Age Factors; Animals; Caffeine; Diffusion; Ear; Humans; In Vitro Techniques; Infant, Newborn; Infant, Premature; Iontophoresis; Lidocaine; Models, Animal; Permeability; Phenobarbital; Skin; Swine | 2004 |
A comparison of Drosophila melanogaster detoxification gene induction responses for six insecticides, caffeine and phenobarbital.
Topics: Animals; Caffeine; Cytochrome P-450 Enzyme System; Drosophila melanogaster; Drosophila Proteins; Enzyme Induction; Esterases; Gene Expression Profiling; Glutathione Transferase; Inactivation, Metabolic; Insecticides; Phenobarbital | 2006 |
Functional analysis of the cis-acting elements responsible for the induction of the Cyp6a8 and Cyp6g1 genes of Drosophila melanogaster by DDT, phenobarbital and caffeine.
Topics: Animals; Caffeine; Cell Line; Cytochrome P-450 Enzyme System; DDT; Drosophila melanogaster; Drosophila Proteins; Drug Synergism; Gene Expression Regulation; Insecticide Resistance; Luciferases; Phenobarbital; Regulatory Elements, Transcriptional; Sequence Analysis, DNA; Xenobiotics | 2010 |
Striking differences in proconvulsant-induced alterations of seizure threshold in two rat models.
Topics: Animals; Anticonvulsants; Caffeine; Central Nervous System Stimulants; Chlorpromazine; Convulsants; Dextroamphetamine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Electroshock; Male; Pentylenetetrazole; Phenobarbital; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Reaction Time; Seizures; Theophylline; Time Factors; Tramadol | 2012 |
Cardiac ryanodine receptor: Selectivity for alkaline earth metal cations points to the EF-hand nature of luminal binding sites.
Topics: Amino Acid Sequence; Animals; Anticonvulsants; Barium; Binding Sites; Caffeine; Calcium; Cations, Divalent; Central Nervous System Stimulants; EF Hand Motifs; Humans; Magnesium; Metals, Alkaline Earth; Molecular Sequence Data; Myocardium; Phenobarbital; Ryanodine Receptor Calcium Release Channel; Sequence Alignment; Strontium | 2016 |
Caffeine Protects Against Anticonvulsant-Induced Neurotoxicity in the Developing Rat Brain.
Topics: Animals; Animals, Newborn; Anticonvulsants; Apoptosis; Brain; Caffeine; Cytokines; gamma-Aminobutyric Acid; Gene Expression; Nerve Degeneration; Neuroprotective Agents; Phenobarbital; Random Allocation; Rats, Wistar; Receptors, Purinergic P1; Time Factors | 2017 |
Caffeine Protects Against Anticonvulsant-Induced Impaired Neurogenesis in the Developing Rat Brain.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anticonvulsants; Brain; Brain-Derived Neurotrophic Factor; Caffeine; Cell Proliferation; DNA-Binding Proteins; Doublecortin Protein; Female; Gene Expression Regulation, Developmental; Hypoxanthine Phosphoribosyltransferase; Male; Nerve Growth Factor; Nerve Tissue Proteins; Neurogenesis; Neurons; Neuroprotective Agents; Neurotrophin 3; PAX6 Transcription Factor; Phenobarbital; Rats; Rats, Wistar; RNA, Messenger; Time Factors | 2018 |
Fabrication and Validation of Gyro-Dot-Optomotor Response Device using Gold Fish to Study Drugs Affecting Visual Perception.
Topics: Animals; Caffeine; Color Perception; Drug Evaluation, Preclinical; Equipment Design; Ethambutol; Eye; Female; Goldfish; Image Processing, Computer-Assisted; Locomotion; Male; Phenobarbital; Photic Stimulation; Reproducibility of Results; Toxicity Tests; Visual Perception | 2016 |
Caffeine intoxication: Behavioral and electrocorticographic patterns in Wistar rats.
Topics: Animals; Anticonvulsants; Caffeine; Diazepam; Pentylenetetrazole; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Seizures | 2022 |
Urgent first-step screening method for ketamine, phenobarbital, zopiclone, zolpidem, phenytoin and thiopental in adulterated soft drink.
Topics: Caffeine; Carbonated Beverages; Female; Humans; Ketamine; Phenobarbital; Phenytoin; Reproducibility of Results; Thiopental; Zolpidem | 2023 |