phenobarbital and baclofen

phenobarbital has been researched along with baclofen in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199015 (46.88)18.7374
1990's10 (31.25)18.2507
2000's3 (9.38)29.6817
2010's4 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Baker, JK; Wall, GM1
Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Haefely, W; Polc, P1
Costa, E; Guidotti, A; Naik, SR1
Beubler, E; Lembeck, F1
Fukusako, T; Morimatsu, M; Nogaki, H; Yamamoto, K1
Amabeoku, GJ; Chikuni, O2
Kikuchi, A; Kim, YS; Takai, Y1
King, JA; Nowack, WJ1
Amabeoku, G1
Fredow, G; Löscher, W1
Mehta, AK; Ticku, MK1
Inoue, M; Matsuo, T; Ogata, N1
Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV1
Armstrong, DR; Ault, B; Gruenthal, M; Nadler, JV; Okazaki, MM1
Czuczwar, SJ; Kleinrok, Z; Kozicka, M1
Chattha, AS; Fromm, GH; Glass, JD; Terrence, CF1
Chmielewska, B; Czuczwar, SJ; Kleinrok, Z; Turski, WA1
Tarika, JS; Winger, G1
Gerard, D; Potashner, SJ1
Bernard, PS; Liebman, JM; Pastor, G; Saelens, JK1
Moshé, SL; Ortíz, J; Ptachewich, Y; Shinnar, S; Velísek, L; Velísková, J1
Stringer, JL1
George, B; Kulkarni, SK1
Klitgaard, H; Margineanu, DG1
Bulloch, MN; Burry, L; Chan, C; Devabhakthuni, S; Dixit, D; Endicott, J; Ramos, L; Tobia, A; Yeung, SY1
Greene, S; Kailainathan, R; Koutsogiannis, Z; Wong, A1

Reviews

2 review(s) available for phenobarbital and baclofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Management of Acute Alcohol Withdrawal Syndrome in Critically Ill Patients.
    Pharmacotherapy, 2016, Volume: 36, Issue:7

    Topics: Baclofen; Benzodiazepines; Critical Illness; Dexmedetomidine; Ethanol; Humans; Length of Stay; Phenobarbital; Substance Withdrawal Syndrome

2016

Other Studies

30 other study(ies) available for phenobarbital and baclofen

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Metabolism of 3-(p-chlorophenyl)pyrrolidine. Structural effects in conversion of a prototype gamma-aminobutyric acid prodrug to lactam and gamma-aminobutyric acid type metabolites.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:6

    Topics: Amino Acids; Animals; Baclofen; Brain; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; gamma-Aminobutyric Acid; Isoniazid; Lactams; Liver; Male; Microsomes; Microsomes, Liver; Mitochondria; Mitochondria, Liver; Molecular Structure; Monoamine Oxidase; Oxidation-Reduction; Prodrugs; Pyrrolidines; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship

1989
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
    Bioorganic & medicinal chemistry, 2007, Nov-15, Volume: 15, Issue:22

    Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption

2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of two benzodiazepines, phenobarbitone, and baclofen on synaptic transmission in the cat cuneate nucleus.
    Naunyn-Schmiedeberg's archives of pharmacology, 1976, Volume: 294, Issue:2

    Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Anti-Anxiety Agents; Baclofen; Bicuculline; Cats; Diazepam; Drug Interactions; Evoked Potentials; Flunitrazepam; Glutamate Decarboxylase; Medulla Oblongata; Neural Inhibition; Phenobarbital; Picrotoxin; Propionates; Semicarbazides; Synapses; Synaptic Transmission

1976
Central GABA receptor agonists: comparison of muscimol and baclofen.
    Neuropharmacology, 1976, Volume: 15, Issue:8

    Topics: Aminobutyrates; Animals; Anticonvulsants; Baclofen; Cerebellum; Cyclic GMP; Diazepam; gamma-Aminobutyric Acid; Harmaline; Isoniazid; Male; Motor Activity; Muscle Tonus; Mycotoxins; Oxazoles; Phenobarbital; Quaternary Ammonium Compounds; Rats; Receptors, Drug; Strychnine; Substance P

1976
Convulsions induced by hyperbaric oxygen: inhibition by phenobarbital, diazepam and baclofen.
    Naunyn-Schmiedeberg's archives of pharmacology, 1977, Volume: 297, Issue:1

    Topics: Aminobutyrates; Animals; Baclofen; Diazepam; Female; gamma-Aminobutyric Acid; Glycine; Hyperbaric Oxygenation; Isoniazid; Male; Mice; Phenobarbital; Rats; Seizures; Strychnine

1977
[Multiple system atrophy with macro square wave jerks and pendular nystagmus].
    Rinsho shinkeigaku = Clinical neurology, 1992, Volume: 32, Issue:11

    Topics: Atrophy; Baclofen; Brain Diseases; Diazepam; Electrooculography; Eye Movements; Female; Humans; Middle Aged; Nystagmus, Pathologic; Phenobarbital; Saccades; Valproic Acid

1992
Effects of some GABAergic agents on quinine-induced seizures in mice.
    Experientia, 1992, Jul-15, Volume: 48, Issue:7

    Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Diazepam; Male; Mice; Mice, Inbred Strains; Muscimol; Phenobarbital; Phenytoin; Quinine; Receptors, GABA-A; Seizures

1992
Effect of chlorpromazine on the smg GDS action.
    Biochemical and biophysical research communications, 1992, Feb-14, Volume: 182, Issue:3

    Topics: Amitriptyline; Baclofen; Blood Platelets; Cell Membrane; Chlorpromazine; Dibucaine; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Humans; Kinetics; Phenobarbital; Phosphatidic Acids; Phospholipids; Propranolol; rap GTP-Binding Proteins

1992
Triphasic waves and spike wave stupor.
    Clinical EEG (electroencephalography), 1992, Volume: 23, Issue:2

    Topics: Aged; Baclofen; Cerebral Cortex; Consciousness Disorders; Electroencephalography; Evoked Potentials; Female; Humans; Muscle Cramp; Neurologic Examination; Phenobarbital

1992
Involvement of GABAergic mechanisms in chloroquine-induced seizures in mice.
    General pharmacology, 1992, Volume: 23, Issue:2

    Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Chloroquine; Diazepam; gamma-Aminobutyric Acid; Male; Mice; Muscimol; Phenobarbital; Seizures

1992
Effects of pharmacological manipulation of GABAergic neurotransmission in a new mutant hamster model of paroxysmal dystonia.
    European journal of pharmacology, 1991, Jan-10, Volume: 192, Issue:2

    Topics: Animals; Baclofen; Carbamazepine; Cricetinae; Diazepam; Disease Models, Animal; Dystonia; gamma-Aminobutyric Acid; Mesocricetus; Mutation; Pentylenetetrazole; Phenobarbital; Phenytoin; Synaptic Transmission; Valproic Acid

1991
Interactions of pentobarbital and phenobarbital with GABAergic drugs against chemoconvulsants in rats.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:4

    Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Diazepam; Drug Interactions; Isoxazoles; Male; Pentobarbital; Phenobarbital; Picrotoxin; Rats; Rats, Inbred Strains; Receptors, GABA-A; Seizures; Strychnine

1988
Potent depressant action of baclofen on hippocampal epileptiform activity in vitro: possible use in the treatment of epilepsy.
    Brain research, 1986, Jul-09, Volume: 377, Issue:2

    Topics: Animals; Anticonvulsants; Baclofen; Carbamazepine; Diazepam; Epilepsy; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Phenobarbital; Synaptic Transmission

1986
Efficacy of baclofen and phenobarbital against the kainic acid limbic seizure-brain damage syndrome.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:2

    Topics: Animals; Baclofen; Behavior, Animal; Brain; Electroencephalography; Injections, Intraventricular; Kainic Acid; Limbic System; Male; Phenobarbital; Rats; Rats, Inbred Strains; Seizures; Time Factors

1986
Kainic acid seizures and neuronal cell death: insights from studies of selective lesions and drugs.
    Advances in experimental medicine and biology, 1986, Volume: 203

    Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Convulsants; Hippocampus; Kainic Acid; Limbic System; Male; Nerve Degeneration; Neural Inhibition; Neural Pathways; Phenobarbital; Rats; Seizures; Time Factors

1986
Effect of dopaminergic and GABA-ergic drugs given alone or in combination on the anticonvulsant action of phenobarbital and diphenylhydantoin in the electroshock test in mice.
    Epilepsia, 1980, Volume: 21, Issue:5

    Topics: Amantadine; Aminooxyacetic Acid; Amphetamine; Animals; Apomorphine; Baclofen; Dopamine; Electroshock; Female; Fluphenazine; gamma-Aminobutyric Acid; Haloperidol; Hydroxybutyrates; Levodopa; Male; Mice; Phenobarbital; Phenytoin; Receptors, Neurotransmitter; Seizures

1980
Role of inhibitory mechanisms in trigeminal neuralgia.
    Neurology, 1981, Volume: 31, Issue:6

    Topics: Animals; Baclofen; Carbamazepine; Cats; Electric Stimulation; Maxillary Nerve; Neural Inhibition; Phenobarbital; Phenytoin; Synaptic Transmission; Trigeminal Neuralgia; Trigeminal Nuclei

1981
Differential effects of baclofen, gamma-hydroxybutyric acid and muscimol on the protective action of phenobarbital and diphenylhydantoin against maximal electroshock-induced seizures in mice.
    Neuropharmacology, 1984, Volume: 23, Issue:2A

    Topics: Animals; Anticonvulsants; Baclofen; Drug Interactions; Electroshock; gamma-Aminobutyric Acid; Hydroxybutyrates; Injections, Intraventricular; Male; Mice; Muscimol; Oxazoles; Phenobarbital; Phenytoin; Sodium Oxybate

1984
The effects of ethanol, phenobarbital, and baclofen on ethanol withdrawal in the rhesus monkey.
    Psychopharmacology, 1980, Volume: 70, Issue:2

    Topics: Alcoholism; Animals; Ataxia; Baclofen; Behavior, Animal; Drug Interactions; Ethanol; Humans; Macaca mulatta; Male; Phenobarbital; Substance Withdrawal Syndrome; Tremor

1980
Kainate-enhanced release of D-[3H]aspartate from cerebral cortex and striatum: reversal by baclofen and pentobarbital.
    Journal of neurochemistry, 1983, Volume: 40, Issue:6

    Topics: Animals; Aspartic Acid; Baclofen; Biological Transport; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glucose; Guinea Pigs; Kainic Acid; Kinetics; Phenobarbital; Pyrrolidines; Sodium; Tritium

1983
Antagonism of intrastriatal and intravenous kainic acid by 1-nuciferine: comparison with various anticonvulsants and GABAmimetics.
    Life sciences, 1980, Nov-24, Volume: 27, Issue:21

    Topics: Animals; Aporphines; Baclofen; Behavior, Animal; Choline O-Acetyltransferase; Corpus Striatum; Diazepam; Excitatory Amino Acid Antagonists; Haloperidol; Injections; Kainic Acid; Male; Phenobarbital; Pyrrolidines; Rats; Seizures

1980
Age-dependent effects of gamma-aminobutyric acid agents on flurothyl seizures.
    Epilepsia, 1995, Volume: 36, Issue:7

    Topics: Age Factors; Animals; Anticonvulsants; Baclofen; Convulsants; Flurothyl; GABA Agents; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Male; Organophosphorus Compounds; Phenobarbital; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, GABA-B; Seizures; Vigabatrin

1995
Alterations in both excitation and inhibition occur before the onset of seizure activity in the hippocampus.
    Epilepsy research, 1993, Volume: 16, Issue:2

    Topics: Animals; Baclofen; Bicuculline; Diazepam; Electric Stimulation; Evoked Potentials; Hippocampus; Ketamine; Kindling, Neurologic; Limbic System; Male; Neurons; Phenobarbital; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Seizures; Stereotaxic Techniques; Synapses

1993
Cimetidine-induced seizures in mice. Antagonism by some GABAergic agents.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Aminobutyrates; Aminooxyacetic Acid; Animals; Baclofen; Bicuculline; Cimetidine; Diazepam; Female; Mice; Muscimol; Phenobarbital; Phenytoin; Picrotoxin; Receptors, GABA; Seizures; Strychnine

1993
Protective effects of GABAergic drugs and other anticonvulsants in lithium-pilocarpine-induced status epilepticus.
    Methods and findings in experimental and clinical pharmacology, 1996, Volume: 18, Issue:5

    Topics: Animals; Anticonvulsants; Baclofen; Clonazepam; Diazepam; Dizocilpine Maleate; Ethanol; GABA Agents; gamma-Aminobutyric Acid; Lithium Chloride; Male; Neuroprotective Agents; Pentobarbital; Phenobarbital; Phenytoin; Pilocarpine; Rats; Rats, Wistar; Status Epilepticus; Valproic Acid

1996
Levetiracetam has no significant gamma-aminobutyric acid-related effect on paired-pulse interaction in the dentate gyrus of rats.
    European journal of pharmacology, 2003, Apr-18, Volume: 466, Issue:3

    Topics: Animals; Anticonvulsants; Baclofen; Bicuculline; Clonazepam; Convulsants; Dentate Gyrus; Diazepam; Electric Stimulation; GABA Agonists; GABA Antagonists; gamma-Aminobutyric Acid; Levetiracetam; Male; Phenobarbital; Piracetam; Rats; Rats, Sprague-Dawley; Receptors, GABA; Synaptic Transmission; Time Factors

2003
Recognition of gamma-hydroxybutyric acid withdrawal: Rapid progression and prolonged symptomatology.
    Emergency medicine Australasia : EMA, 2017, Volume: 29, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Australia; Baclofen; Benzodiazepines; Diazepam; Humans; Hydroxybutyrates; Male; Penicillanic Acid; Phenobarbital; Piperacillin; Pneumonia; Psychomotor Agitation; Substance Withdrawal Syndrome; Sweating; Tazobactam; Tremor

2017