phenobarbital has been researched along with azathioprine in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (68.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (9.09) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kaplowitz, N | 1 |
| Hobara, N; Nagashima, H; Watanabe, A | 1 |
| Balthazar, A; Rosman, PM; Sacerdote, A; Wallace, EZ | 1 |
| Hirayama, C; Ikawa, S; Yamanishi, Y | 1 |
| Brunner, G | 1 |
| Kovalev, IE; Rubtsova, ER; Shaĭdrov, VV | 1 |
| Lynn James, GW; Parker, FL; Pickering, RW | 1 |
| Chibowski, D; Pawłowska-Wakowicz, B; Siezieniewska, Z; Tryksza, J | 2 |
| Mörl, M | 1 |
| Celiński, K; Chibowski, D; Chodkowska, A; Czarnecki, J; Pokora, J; Radwan, P; Siezieniewska, Z | 2 |
| Brunner, G; Grünewälder, H; Perings, E; Vido, I | 1 |
| Gips, CH | 1 |
| Rodríguez-San Román, JL; Rull, S; Velilla, JP | 1 |
2 review(s) available for phenobarbital and azathioprine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Current aspects of primary biliary cirrhosis (2)].
Topics: Azathioprine; Biliary Tract Diseases; Cholestyramine Resin; Cyclosporins; Diagnosis, Differential; Humans; Liver Cirrhosis, Biliary; Liver Diseases; Minerals; Penicillamine; Phenobarbital; Plasmapheresis; Prognosis; Vitamins | 1983 |
20 other study(ies) available for phenobarbital and azathioprine
| Article | Year |
|---|---|
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Enzymatic thiolysis of azathioprine in vitro.
Topics: Animals; Azathioprine; Enzyme Induction; Glutathione; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Mercaptopurine; Phenobarbital; Rats | 1976 |
[Biochemical and morphological study on hepato-toxicity of azathioprine in rat (author's transl)].
Topics: Alkaline Phosphatase; Animals; Azathioprine; Chemical and Drug Induced Liver Injury; gamma-Glutamyltransferase; Liver; Liver Diseases; Phenobarbital; Rats | 1979 |
Adrenocortical carcinoma in a patient with systemic lupus erythematosus treated with azathioprine.
Topics: Adrenal Cortex Neoplasms; Azathioprine; Humans; Lupus Erythematosus, Systemic; Male; Middle Aged; Neoplasm Metastasis; Phenobarbital; Phenytoin; Prednisone | 1979 |
Serum squalene levels in hepatobiliary diseases.
Topics: Acute Disease; Adult; Azathioprine; Biliary Tract Diseases; Cholestasis; Cholesterol; Cholestyramine Resin; Chronic Disease; Female; Hepatitis; Humans; Liver Cirrhosis; Liver Cirrhosis, Biliary; Liver Diseases; Male; Phenobarbital; Squalene | 1978 |
[Therapy of the chronic destructive, non-purulent cholangitis (primary biliary cirrhosis)].
Topics: Azathioprine; Calcium; Cholangitis; Cholestyramine Resin; Clofibrate; Humans; Hypercholesterolemia; Liver Cirrhosis, Biliary; Osteoporosis; Phenobarbital; Pruritus; Vitamin D | 1976 |
[Influence of phenobarbital on the immunodepressive action of antitumor substances].
Topics: Animals; Antibody Formation; Azathioprine; Cyclophosphamide; Drug Interactions; Immune Adherence Reaction; Mercaptopurine; Mice; Phenobarbital; Spleen | 1976 |
Inhibition, by drugs, of galactosamine induced hepatitis in the rat.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Azathioprine; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Galactosamine; Liver; Male; Orotic Acid; Phenobarbital; Prednisolone; Rats | 1975 |
[Morphological and histochemical observations in rat liver after toxic damage with imuran. I].
Topics: Animals; Azathioprine; Drug Interactions; Liver; Male; Phenobarbital; Rats; Rats, Wistar | 1988 |
[Ultrastructural observations of rat liver, previously induced by phenobarbital after toxic damage with imuran. II].
Topics: Animals; Azathioprine; Drug Interactions; Endoplasmic Reticulum; Liver; Male; Mitochondria, Liver; Phenobarbital; Rats; Rats, Wistar | 1988 |
[Are there new aspects in the therapy of primary biliary cirrhosis?].
Topics: Azathioprine; Bile Acids and Salts; Bilirubin; Cyclosporins; Humans; Liver Cirrhosis, Biliary; Liver Transplantation; Penicillamine; Phenobarbital; Plasmapheresis | 1986 |
[Experimental examination of the influence of Imuran (azathioprine) on the content of hydroxyproline in perfusion fluid of isolated liver in healthy rats and after chronic CCl4 poisoning].
Topics: Animals; Azathioprine; Carbon Tetrachloride Poisoning; Drug Interactions; Hydroxyproline; In Vitro Techniques; Liver; Male; Perfusion; Phenobarbital; Prednisone; Rats; Rats, Inbred Strains | 1985 |
[Experimental examination of the interaction and inducing influence of Imuran (azathioprine) on healthy and injured parenchymatous cells of rat liver].
Topics: Animals; Azathioprine; Carbon Tetrachloride Poisoning; Drug Interactions; Enzyme Induction; Liver; Perfusion; Phenobarbital; Prednisone; Rats; Rats, Inbred Strains | 1985 |
[Studies on the effects of azathioprine, choline orotate and phenobarbital on enzymes of the endoplasmatic reticulum and mitochondria of rat liver].
Topics: Acyltransferases; Animals; Aspartate Aminotransferases; Azathioprine; Choline; Cytochrome c Group; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Glucuronates; Liver; Male; Microsomes, Liver; Mitochondria, Liver; NADP; Orotic Acid; Oxidoreductases; Phenobarbital; Rats; Succinate Dehydrogenase | 1972 |
Reflections on the treatment of itch in primary biliary cirrhosis.
Topics: Adult; Azathioprine; Child, Preschool; Cholangitis; Cholestyramine Resin; Female; Humans; Phenobarbital; Pruritus | 1973 |