phenobarbital and androstenedione

phenobarbital has been researched along with androstenedione in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199019 (61.29)18.7374
1990's10 (32.26)18.2507
2000's2 (6.45)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Hansson, A; Ingelman-Sundberg, M; Johansson, I1
Ernster, L; Gustafsson, JA; Hrycay, EG; Ingelman-Sundberg, M1
Gulyaeva, LF; Khatsenko, OG; Lyakhovich, VV; Mishin, VM1
Cantrill, E; Farrell, GC; Martini, R; Murray, M1
Holsztynska, EJ; Iscan, M; Lester, R; Radominska, A; Waxman, DJ; Zimniak, P1
Marks, GS; McGilvray, I; Riddick, DS1
Murray, M; Reidy, GF1
Guliaeva, LF; Khatsenko, OG; Liakhovich, VV; Mishin, VM1
Horst, D; Nakamura, Y; Saville, L; Terranova, PF; Uilenbroek, JT1
Gutkina, NI; Khatsenko, OG; Lyakhovich, VV; Mishin, VM; Obraztsov, VV; Shekhtman, DG1
Cantrill, E; Farrell, GC; Murray, M1
Andersson, T; Förlin, L; Goksøyr, A; Hansson, T; Klungsøyr, J; Zhang, Y1
Garza, F; Na, JY; Terranova, PF1
O'Brien, PJ; Rahimtula, AD1
Alvares, VP; Bickers, DR; Bradlow, HL; Fukushima, DK; Hellman, L; Kappas, A; Zumoff, B1
Garza, F; Terranova, PF1
Gustafsson, JA; Hansson, T; Rafter, J1
Ingelman-Sundberg, M; Johansson, I1
Terranova, PF1
DePierre, JW; Meijer, J2
Martin, NC; Terranova, PF1
Ascanio, LE; Terranova, PF1
Gustafsson, JA; Ingelman-Sundberg, M; Nilsen, OG; Toftgård, R1
Nakamura, Y; Ueda, S1
Bertrand, J; Forest, MG; Lecoq, A; Salle, B1
Costelli, P; Fonzi, S; Galimberti, CA; Manni, R; Murialdo, G; Parodi, C; Polleri, A; Solinas, GP; Tartara, A; Torre, F1
Grimm, SW; Halpert, JR; Kedzie, KM; Philpot, RM; Ryan, R1
Halpert, JR; Klekotka, PA1
Baader, M; Fraser, D; Halpert, JR; Meyer, UA; Ourlin, JC1

Other Studies

31 other study(ies) available for phenobarbital and androstenedione

ArticleYear
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Catalytic properties of the liver microsomal hydroxylase system in reconstituted phospholipid vesicles.
    Acta biologica et medica Germanica, 1979, Volume: 38, Issue:2-3

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Liposomes; Male; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Phenobarbital; Phosphatidylcholines; Rabbits; Steroid Hydroxylases

1979
Sodium periodate, sodium chloride, organic hydroperoxides, and H2O2 as hydroxylating agents in steroid hydroxylation reactions catalyzed by partially purified cytochrome P-450.
    Biochemical and biophysical research communications, 1975, Sep-02, Volume: 66, Issue:1

    Topics: Androstenedione; Animals; Chlorine; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Kinetics; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Periodic Acid; Peroxides; Phenobarbital; Rats; Steroid Hydroxylases

1975
Dynamics of androstenedione metabolite formation in rat liver microsomes during temporal phenobarbital induction.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1991, Volume: 99, Issue:3

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hydroxylation; Isoenzymes; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains

1991
Increased expression of cytochrome P450 IIIA2 in male rat liver after dietary vitamin A supplementation.
    Archives of biochemistry and biophysics, 1991, May-01, Volume: 286, Issue:2

    Topics: Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Diet; Diterpenes; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Progesterone; Rats; Rats, Inbred Strains; Reference Values; Retinyl Esters; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Vitamin A

1991
Distinct forms of cytochrome P-450 are responsible for 6 beta-hydroxylation of bile acids and of neutral steroids.
    The Biochemical journal, 1991, Apr-01, Volume: 275 ( Pt 1)

    Topics: Androstenedione; Animals; Bile Acids and Salts; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Hydroxylation; Lithocholic Acid; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344; Rats, Inbred Strains; Steroid Hydroxylases; Steroids

1991
Inactivation of rat liver microsomal steroid hydroxylations by 4-alkyl analogues of 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-trimethylpyridine: evidence for selectivity among steroid-inducible cytochrome P450IIIA forms.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:12

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Enzyme Induction; Female; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Steroids

1990
Evidence for complexation of P-450 IIC6 by an orphenadrine metabolite.
    Biochemical and biophysical research communications, 1990, Jan-30, Volume: 166, Issue:2

    Topics: Androstenedione; Animals; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ferricyanides; Kinetics; Microsomes, Liver; Orphenadrine; Oxidoreductases; Phenobarbital; Progesterone; Rats; Steroid Hydroxylases

1990
[Evaluation of catalytic activity of multiple forms of cytochrome P-450 in liver microsomes of Wistar rats by androstenedione metabolism].
    Biokhimiia (Moscow, Russia), 1990, Volume: 55, Issue:2

    Topics: Androstenedione; Animals; Catalysis; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hydroxylation; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains

1990
Serotonin enhances oestradiol production by hamster preovulatory follicles in vitro: effects of experimentally induced atresia.
    The Journal of endocrinology, 1990, Volume: 125, Issue:3

    Topics: Androstenedione; Animals; Cells, Cultured; Cricetinae; Estradiol; Female; Follicular Atresia; Follicular Phase; Granulosa Cells; Ketanserin; Mesocricetus; Mianserin; Organ Culture Techniques; Ovarian Follicle; Phenobarbital; Serotonin

1990
The phenobarbital-type induction of rat liver microsomal monooxygenases by perfluorodecalin.
    Chemico-biological interactions, 1989, Volume: 72, Issue:1-2

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Fluorocarbons; Immunodiffusion; Immunoelectrophoresis; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Inbred Strains

1989
Hepatic microsomal metabolism of androst-4-ene-3,17-dione: relative importance of ring hydroxylation and aromatization in control and induced rat liver.
    Journal of steroid biochemistry, 1988, Volume: 29, Issue:2

    Topics: Androstenedione; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Estradiol; Estrone; Hydroxylation; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Reference Values

1988
Species characteristics of the hepatic xenobiotic and steroid biotransformation systems of two teleost fish, Atlantic cod (Gadus morhua) and rainbow trout (Salmo gairdneri).
    Toxicology and applied pharmacology, 1987, Volume: 89, Issue:3

    Topics: 7-Alkoxycoumarin O-Dealkylase; Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Biotransformation; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethylmorphine-N-Demethylase; Female; Fishes; Liver; Male; Microsomes, Liver; Oxidoreductases; Oxygenases; Phenobarbital; Salmonidae; Species Specificity; Steroids; Trout

1987
Alterations in follicular fluid steroids and follicular hCG and FSH binding during atresia in hamster.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 179, Issue:1

    Topics: Androstenedione; Animals; Body Fluids; Chorionic Gonadotropin; Cricetinae; Estradiol; Estrus; Female; Follicle Stimulating Hormone; Follicular Atresia; Gonadal Steroid Hormones; Ovarian Follicle; Ovulation; Phenobarbital; Pregnancy; Proestrus; Progesterone; Radioimmunoassay; Time Factors

1985
Hydroperoxide catalyzed liver microsomal aromatic hydroxylation reactions involving cytochrome P-450.
    Biochemical and biophysical research communications, 1974, Sep-09, Volume: 60, Issue:1

    Topics: Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Coumarins; Cyanides; Cytochrome P-450 Enzyme System; Edetic Acid; Hydrogen-Ion Concentration; Kinetics; Magnesium; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Phenobarbital; Phenols; Phenylenediamines; Proadifen; Rabbits; Rats; Sodium Dodecyl Sulfate; Species Specificity; Superoxide Dismutase; Time Factors

1974
Drug-induced alterations of steroid hormone metabolism in man.
    Annals of the New York Academy of Sciences, 1973, Volume: 212

    Topics: Adult; Androgens; Androstenedione; Androsterone; Child; Dichlorodiphenyldichloroethane; Humans; Hydrocortisone; Hydroxylation; Lead Poisoning; Phenobarbital; Testosterone

1973
Relationship between the preovulatory luteinizing hormone (LH) surge and androstenedione synthesis of preantral follicles in the cyclic hamster: detection by in vitro responses to LH.
    Biology of reproduction, 1983, Volume: 29, Issue:3

    Topics: Androstenedione; Animals; Cricetinae; Estradiol; Estrus; Female; Follicle Stimulating Hormone; In Vitro Techniques; Luteinizing Hormone; Ovarian Follicle; Ovulation; Phenobarbital; Pregnancy; Progesterone

1983
Effects of some common inducers on the hepatic microsomal metabolism of androstenedione in rainbow trout with special reference to cytochrome P-450-dependent enzymes.
    Biochemical pharmacology, 1980, Feb-15, Volume: 29, Issue:4

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Pregnenolone Carbonitrile; Salmonidae; Trout

1980
Catalytic properties of purified forms of rabbit liver microsomal cytochrome P-450 in reconstituted phospholipid vesicles.
    Biochemistry, 1980, Aug-19, Volume: 19, Issue:17

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Kinetics; Liposomes; Microsomes, Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Phospholipids; Rabbits; Substrate Specificity

1980
Effects of phenobarbital-induced ovulatory delay on the follicular population and serum levels of steroids and gonadotropins in the hamster: A model for atresia.
    Biology of reproduction, 1980, Volume: 23, Issue:1

    Topics: Androstenedione; Animals; Cricetinae; Estradiol; Female; Follicle Stimulating Hormone; Luteinizing Hormone; Ovarian Follicle; Ovulation; Phenobarbital; Progesterone

1980
Comparison of trans-stilbene oxide, phenobarbital and 3-methylcholanthrene as inducers of steroid metabolism by the rat liver microsomal cytochrome P-450 system.
    Journal of steroid biochemistry, 1983, Volume: 18, Issue:4

    Topics: Androstenedione; Animals; Benzoflavones; Cytochrome P-450 Enzyme System; Hydroxylation; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Stilbenes; Testosterone

1983
Effects of delayed ovulation on pregnancy in the PMSG-treated immature rat.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 169, Issue:2

    Topics: Androstenedione; Animals; Blastocyst; Embryo Implantation; Estradiol; Female; Gonadotropins, Equine; Ovulation; Phenobarbital; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Sexual Maturation

1982
Alterations of ovarian steroidogenesis induced by ovulatory delay in immature rats treated with pregnant mare serum gonadotropin.
    Biology of reproduction, 1982, Volume: 26, Issue:1

    Topics: Aging; Androstenedione; Animals; Estradiol; Female; Gonadotropins, Equine; Kinetics; Luteinizing Hormone; Ovary; Ovulation; Phenobarbital; Pregnancy; Proestrus; Progesterone; Rats; Rats, Inbred Strains

1982
Changes in the matabolism of steroid hormones by the rat liver cytochrome P-450 system after induction with trans-stilbene oxide.
    Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1981, Volume: 35, Issue:2

    Topics: Androstenedione; Animals; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Stilbenes; Testosterone

1981
Correlation between changes in enzymatic activities and induction of different forms of rat liver microsomal cytochrome P-450 after phenobarbital-, 3-methylcholanthrene- and 16 alpha-cyanopregnenolone treatment.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:5

    Topics: Androstane-3,17-diol; Androstenedione; Animals; Benzopyrenes; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Organ Size; Phenobarbital; Pregnenolone; Rats

1980
16 beta-hydroxylation of 4-androstene-3,17-dione in phenobarbital-pretreated rat liver microsomes.
    FEBS letters, 1980, May-05, Volume: 113, Issue:2

    Topics: Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Enzyme Induction; Hydroxylation; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rats; Steroid Hydroxylases

1980
Does neonatal phenobarbital treatment affect testicular and adrenal functions and steroid binding in plasma in infancy?
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 52, Issue:1

    Topics: Adrenal Glands; Androstenedione; Humans; Hydrocortisone; Hydroxyprogesterones; Infant, Newborn; Infant, Premature, Diseases; Jaundice, Neonatal; Longitudinal Studies; Male; Phenobarbital; Receptors, Steroid; Testis; Testosterone

1981
Sex hormones, gonadotropins and prolactin in male epileptic subjects in remission: role of the epileptic syndrome and of antiepileptic drugs.
    Neuropsychobiology, 1994, Volume: 30, Issue:1

    Topics: Adult; Androstenedione; Anticonvulsants; Carbamazepine; Dihydrotestosterone; Epilepsies, Partial; Epilepsy, Generalized; Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Male; Middle Aged; Phenobarbital; Phenytoin; Prolactin; Sex Hormone-Binding Globulin; Testosterone; Thyrotropin-Releasing Hormone

1994
Cloning, sequencing, and functional studies of phenobarbital-inducible forms of cytochrome P450 2B and 4B expressed in rabbit kidney.
    Archives of biochemistry and biophysics, 1993, Aug-01, Volume: 304, Issue:2

    Topics: Amino Acid Sequence; Androstenedione; Animals; Base Sequence; Cloning, Molecular; Coumarins; Cytochrome P-450 Enzyme System; DNA Probes; Enzyme Induction; Kidney; Molecular Sequence Data; Phenobarbital; Rabbits; Recombinant Proteins; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Species Specificity; Steroid Hydroxylases; Tissue Distribution

1993
Benzyloxyresorufin as a specific substrate for the major phenobarbital-inducible dog liver cytochrome P450 (P4502B11).
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:12

    Topics: Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Dogs; Enzyme Induction; In Vitro Techniques; Kinetics; Microsomes, Liver; Oxazines; Phenobarbital; Steroid Hydroxylases; Substrate Specificity

1995
Cloning and functional expression of a first inducible avian cytochrome P450 of the CYP3A subfamily (CYP3A37).
    Archives of biochemistry and biophysics, 2000, Jan-15, Volume: 373, Issue:2

    Topics: Amino Acid Sequence; Androstenedione; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Cells, Cultured; Chick Embryo; Chickens; Cloning, Molecular; COS Cells; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Molecular Sequence Data; Oxidoreductases, N-Demethylating; Phenobarbital; Phylogeny; Progesterone; RNA, Messenger; Sequence Alignment; Substrate Specificity; Testosterone

2000