phenobarbital has been researched along with aminopyrine in 261 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 243 (93.10) | 18.7374 |
| 1990's | 11 (4.21) | 18.2507 |
| 2000's | 5 (1.92) | 29.6817 |
| 2010's | 2 (0.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caron, G; Ermondi, G | 1 |
| Baert, B; Beetens, J; Bodé, S; De Spiegeleer, B; Deconinck, E; Lambert, J; Slegers, G; Slodicka, M; Stoppie, P; Van Gele, M; Vander Heyden, Y | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Hildebrandt, AG; Kewitz, H; Roots, I; Saalfrank, K; Speck, M | 1 |
| Chance, B; Oshino, N | 1 |
| Klinger, W; Muller, D | 1 |
| Bartoli, GM; Dani, A; Galeotti, T; Russo, M; Terranova, T | 1 |
| Chance, B; Jamieson, D; Oshino, N | 1 |
| Marazzo, DP; Thurman, RG | 1 |
| Jansson, I; Schenkman, JB | 1 |
| Hildebrandt, AG; Roots, I; Saalfrank, K | 1 |
| Caygill, CP; Diplock, AT; Giasuddin, AS; Jeffery, EH | 1 |
| Budevsky, O; Chakarova, P | 1 |
| Engel, P | 1 |
| Gourlay, GK; Savage, JK; Stock, BH | 1 |
| Benes, I; Blum, AL; Haemmerli, UP; Herz, R; Koelz, HR | 1 |
| Chodkowska, A; Czarnecki, J; Gieroba, J; Pokora, J; Radwan, P | 1 |
| Hart, FE; Hew, JT; Willson, RA | 1 |
| Hammer, CT; Wills, ED | 1 |
| Sies, H; Stokstad, EL; Waydhas, C | 1 |
| Hepner, GW; Piken, E | 1 |
| Schwab, H; Sies, H | 1 |
| Bartoli, GM; Burk, RF; Sies, H; Waydhas, C | 1 |
| Brändle, E; Lutz, WK; Zbinden, G | 1 |
| Fawade, MM; Pawar, SS | 1 |
| Agosin, M; Capdevila, J; Naquira, C; Paulin, J | 1 |
| Bock, KW; Remmer, H; Rexer, B | 1 |
| Gram, TE; Guarino, AM; Litterst, CL; Mimnaugh, EG; Simon, RC | 1 |
| Galdhar, NR; Pawar, SS | 1 |
| Holscher, MA; Hunter, AL; Neal, RA | 1 |
| Piasecka, H; Zakrzewski, Z | 1 |
| Hepner, GW | 1 |
| Chistiakov, VV; Lavretskaia, EF; Libinzon, RE; Mal'dov, DG; Ratnikov, LA | 1 |
| Kuga, T; Moroi, K; Satoh, T; Ushiyama, S | 1 |
| Berte, F; De Bernardi, M; Manzo, L | 1 |
| Lieber, CS; Pirola, RC | 1 |
| Gangolli, SD; Heading, CE; Lake, BG; Lloyd, AG; Phillips, JC | 1 |
| Bircher, J; Lauterburg, BH | 1 |
| Beck, G; Chasserot-Golaz, S | 1 |
| Adrianov, NV; Archakov, AI; Dovgiĭ, AI; Kuong, DD; Varenitsa, AI | 1 |
| Gong, HL; Wang, GF; Wu, YT | 1 |
| Branch, RA; Wensing, G | 1 |
| Abounassif, MA; Gad-Kariem, EA; Wahbi, AM | 1 |
| Premereur, N; Roels, F; Van den Branden, C | 1 |
| Gelboin, HV; Park, SS; Slusher, LB; Vesell, ES | 1 |
| Fedchenko, LG; Neĭmark, EZ; Stegniĭ, AS | 1 |
| Heubel, F; Netter, KJ; Vesell, ES | 1 |
| Adrianov, NV; Dovgiĭ, AI | 1 |
| Adrianov, NV; Dovgiĭ, AI; Khaĭlov, PM | 1 |
| Hoshi, K; Igarashi, T; Kitagawa, H; Satoh, T; Senda, N; Ueno, K | 1 |
| Ballatori, N; Truong, AT | 1 |
| Hanzlik, RP; Traiger, GJ; Vyas, KP | 1 |
| Gascon-Barré, M; Huet, PM; Vallières, S | 1 |
| Sommer, L; Zysset, T | 1 |
| Anzenbacher, P; Burkhard, J; Hodek, P; Janků, J; Janscák, P; Vodicka, L | 1 |
| Wu, Q; Yang, JY | 1 |
| Fermus, R; Figurski, R; Hański, W | 1 |
| Funae, Y; Imaoka, S; Inoue, K | 1 |
| Firsova, VI; Komov, VP; Vennikas, OR | 1 |
| Dobkina, EE; Kon', IIa; Martinchik, AN | 1 |
| Hayes, EP; Scala, P; Witz, G | 1 |
| Black, KA; Coffman, BL; Dannan, GA; Green, MD; Guengerich, FP; Tephly, TR | 1 |
| Brandt, I; Klasson-Wehler, E; Lund, BO | 1 |
| Breimer, DD; de Bree, H; Heij, P; van der Graaff, M; Vermeulen, NP | 1 |
| Antoni, F; Bánhegyi, G; Garzó, T; Mandl, J | 1 |
| Li, YD; Luo, GA; Wang, YM | 1 |
| Bien, E; Witt, M | 1 |
| Bien, E; Gebert, I; Skorka, G | 1 |
| Andrianov, NV; Archakov, AI; Dovgiĭ, AI | 1 |
| Dolgov, AV; Grek, OR; Sharapov, VI; Shkurupiĭ, VA; Sokirchenko, IA | 1 |
| Osin'kovskaia, ND; Rubenchik, BL | 1 |
| Adam, SE; Ford, EJ; Gopinath, C | 1 |
| Berggren, M; Ericsson, JL; Rane, A; Yaffe, S | 1 |
| Jondorf, WR; Miller, HH | 1 |
| Fujita, T; Mannering, GJ | 1 |
| Hildebrandt, AG; Roots, I; Speck, M | 1 |
| Hansen, W; Scholz, R; Thurman, RG | 1 |
| Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; McCay, PB; Poyer, JL | 1 |
| Patel, JM; Pawar, SS | 2 |
| Albrecht, R; Manchon, P; Pélissier, MA; Rospars, JP | 1 |
| Martin, YC | 1 |
| Onoe, T | 1 |
| Kleine-Natrop, HE | 1 |
| Bickel, MH; Gigon, PL | 1 |
| Castro, JA; Gomez, MI | 1 |
| Hildebrandt, AG; Roots, I | 2 |
| Hildebrandt, AG; Roots, I; Saalfrank, K; Speck, M | 1 |
| Kotake, T; Sakamoto, Y; Shimakawa, H; Takasugi, M; Wada, F | 1 |
| Cockrill, BL; Platt, DS | 1 |
| Wilson, JT | 3 |
| Heni, N; Remmer, H | 1 |
| Drake, R; McDaniel, O; Nelson, BD | 1 |
| Bompiani, R; D'Amico, E; Galotti, T; Marchese, E; Russo, M; Terranova, T | 1 |
| Beyrich, T; Schleuder, M | 1 |
| Ericsson, JL; Ernster, L; Orrenius, S | 1 |
| Imai, Y; Sato, R | 1 |
| Kato, R | 3 |
| Fouts, JR; Gram, TE; Wilson, JT | 1 |
| Das, ML; Ernster, L; Orrenius, S | 1 |
| Kato, R; Onoda, K; Takahashi, A; Takanaka, A | 1 |
| Fouts, JR; Peters, MA | 2 |
| Ahmad, N; Brindley, WA | 1 |
| Coon, MJ; Lu, AY; Strobel, HW | 1 |
| Scholz, R; Thurman, RG | 2 |
| Leibman, KC | 1 |
| Donahue, JD; Johnson, RK; Jondorf, WR; Miller, HH | 1 |
| Scholz, R; Thurman, G | 1 |
| Jakobsson, S; Orrenius, S; Thor, H | 1 |
| Topham, JC | 1 |
| Masters, BS; Ziegler, DM | 1 |
| Gnosspelius, Y; Orrenius, S; Thor, H | 1 |
| Glazer, RI; Sartorelli, AC; Schenkman, JB | 1 |
| Flynn, EJ; Lynch, M; Zannoni, VG | 1 |
| Kupfer, D; Levin, E | 1 |
| McIntosh, DA; Topham, JC | 1 |
| Becking, GC | 1 |
| Allen, LM; Creaven, PJ | 1 |
| Röttger, HJ; Windorfer, A | 1 |
| Carpenter, MP; Howard, CN | 1 |
| Hepner, GW; Vesell, ES | 1 |
| Diplock, AT | 1 |
| Franke, H; Günther, M; Hoffmann, H; Traeger, A | 1 |
| Jori, A; Pugliatti, C; Santini, V | 1 |
| Drummond, AH; Jondorf, WR; McCall, JM | 1 |
| Agosin, M; Capdevila, J; Morello, A; Perry, AS | 1 |
| Bradley, SG; Munson, AE; Rose, WC | 1 |
| Century, B | 1 |
| Schwarz, CM; Schwarz, KG | 1 |
| Filippich, LJ; Seawright, AA; Steele, DP | 1 |
| Bojanek, J; Wańkowicz, B | 1 |
| Momose, S; Takagaki, E; Tanayama, S | 1 |
| Couch, DB; Friedman, MA | 1 |
| Dean, ME; Stock, BH | 1 |
| Götz, HG | 1 |
| Fouts, JR | 2 |
| Klinger, V | 2 |
| Neal, RA; Roth, JA | 1 |
| Hassinen, IE; Ylikahri, RH | 1 |
| Neal, RA; Schulert, AR; Siami, G | 1 |
| Bishop, R; Mudie, AW; Seawright, AA; Steele, DP | 1 |
| Windorfer, A | 1 |
| Remmer, H | 1 |
| Aust, SD; Stevens, JB | 1 |
| Feuer, G; Lumb, G; Moddel, G; Sosa-Lucero, JC | 1 |
| Lechner, MC; Pousada, CR | 1 |
| Kálmán, J; Küttel, D; Tóth, K | 1 |
| Marchand, P; Witschi, HP | 1 |
| Pasechnikov, FG | 1 |
| Klinger, W; Reinicke, C | 1 |
| Marshall, WJ | 1 |
| Filipescu, A; Spirescu, J | 1 |
| Kato, R; Oshima, T; Takayanagi, M | 1 |
| Kato, R; Omori, Y; Onoda, K; Takanaka, A | 1 |
| Fujimoto, M; Kitahara, A; Miyao, K; Ogo, T | 1 |
| Dehn, F; LeValley, SE; Lombrozo, L; Mitoma, C | 1 |
| Marshall, WJ; McLean, AE | 2 |
| Benzi, G; Berte', F; De Bernardi, M; Manzo, L | 1 |
| Fuller, GC; Louis-Ferdinand, RT | 1 |
| Schnell, U | 1 |
| Degkwitz, E; Leber, HW; Staudinger, H | 2 |
| Leibman, KC; Sunderman, FW | 1 |
| Holsti, LR; Mattila, MJ; Takki, S; Venho, VM | 1 |
| Kato, R; Takanaka, A; Takayanaghi, M | 1 |
| Beuthin, PK; Bousquet, WF | 1 |
| Aust, SD; Pederson, TC | 1 |
| Henderson, PT; Kersten, KJ | 1 |
| Oppelt, WW; Remmer, H; Ross, WE; Zange, M | 1 |
| Cygler, J; Maciejowska, E; Moskalewska, K; Plonka, T | 1 |
| Argyris, TS | 2 |
| Potrepka, RF; Spratt, JL | 1 |
| Douglas, JF; Edelson, J | 1 |
| Calderoni, FJ; Mitoma, C; Neubauer, SE; Tagg, JS; Tanabe, M; Yasuda, D | 1 |
| Huidobro, F; Huidobro, JP; Larraín, G | 1 |
| Cieszyński, T | 1 |
| Ibrahim, I; Sulman, FG; Weller, CP | 1 |
| Einarsson, K; Johansson, G | 1 |
| Bertè, F; De Bernardi, M; Hokari, S; Manzo, L | 1 |
| Maki, Y | 1 |
| Fuller, GC; Lal, H; Olshan, AM | 1 |
| Hirata, K; Sakamoto, Y; Wada, F | 1 |
| Guarino, AM; Hart, LG; Schanker, LS | 1 |
| Culp, HW; Gibson, WR; Marshall, FJ; McMahon, RE; Miller, WM; Mills, J | 1 |
| Ichii, S; Yago, N | 1 |
| Dubois, KP; Tardiff, RG | 1 |
| Donahue, JD; Johnson, RK; Jondorf, WR | 1 |
| Creighton, JM; Marks, GS | 1 |
| Fouts, JR; Gram, TE | 1 |
| Fouts, JR; Wilson, JT | 1 |
| Haraszti, A; Urbán, G | 1 |
| Büch, H; Forth, W; Karachristianidis, G; Pfleger, K; Wörner, D | 1 |
| Fouts, JR; Gram, TE; Rogers, LA | 1 |
| Houston, JB; Lockwood, GF | 1 |
| Leonenko, OB | 1 |
| Fujimori, K; Inoue, K; Kasuya, Y; Mizokami, K; Omori, Y; Sunouchi, M; Takanaka, A | 1 |
| Mishin, VM; Mishina, DV | 1 |
| Butler, KW; Deslauriers, R; Geoffrion, Y; Pass, MA; Smith, IC | 1 |
| Helge, H; Jäger-Roman, E; Kuhnz, W; Nau, H; Rating, D | 1 |
| Majlát, P | 1 |
| Buchet, JP; Geubel, A; Lauwerys, R; Mahieu, P; Pauwels, S | 1 |
| Boĭm, TM; Rubenchik, BL; Tsapenko, VF | 1 |
| Døssing, M; Pilsgaard, H; Poulsen, HE; Rasmussen, B | 1 |
| Aristov, VN; Gichev, IuP; Red'kin, IuV; Taskaev, II | 1 |
| Bien, E | 1 |
| Goto, S; Iguchi, S; Matsuyama, K; Noda, A; Tanaka, T | 1 |
| Buchet, JP; de Hoffmann, E; Lauwerys, R; Scailteur, V | 1 |
| Isa, Y; Kanzaki, T; Kurokawa, N; Nomura, T; Sakamoto, Y; Tada, E; Tanaka, H | 1 |
| Guliamov, MG | 1 |
| Gramatzki, S; Heinemeyer, G; Hildebrandt, AG; Nigam, S; Roots, I | 1 |
| Bieri, HU; Bircher, J | 1 |
| Kosior, A; Nerlo, H | 1 |
| Larson, RE; Moldowan, MJ; Wilson, VL | 1 |
| Isa, Y; Nomura, T | 1 |
| Bornschein, M; Grohmann, A; Voigt, R | 1 |
| Iyanagi, T; Kobayashi, S; Suzaki, T | 1 |
| Häuser, I; Helge, H; Jäger, E; Koch, S; Nau, H; Rating, D | 1 |
| Czok, G; Finke, A | 1 |
| Bandou, R; Goromaru, T; Kiwada, H; Maeda, H; Matsuki, Y | 1 |
| Branch, RA; Sabra, R; Wensing, G | 1 |
| Grevel, J; Kahan, BD; Napoli, KL; Serino, F; Strobel, HW | 1 |
| Brazier, JL; Géloën, A; Minaire, Y; Mion, F; Rousseau, M | 1 |
| Konishi, H; Morita, K; Yamaji, A | 1 |
| Géloën, A; Gemayel, J; Mion, F | 1 |
| HIGUCHI, T; KURAMOTO, R | 1 |
| LUSTIG, B | 1 |
| STOLL, P | 1 |
| WOLF, N | 1 |
| CHIESARA, E; KATO, R; VASSANELLI, P | 1 |
| NEUHAUS, G; REMMER, H; SIEGERT, M | 1 |
| SERVERDUPUY, JM | 1 |
| GEORGESCU, C; GOCIU, M; MARCUS, N; PAUN, R; POPESCU, IG | 1 |
| DIXON, RL; FOUTS, JR; HART, LG; ROGERS, LA | 1 |
| COLLINS, RJ; MACGREGOR, DW; WEEKS, JR | 1 |
| KRAUS, L; VEPROVSKA, E | 1 |
| BRESNICK, E; YANG, HY | 1 |
| BURNS, JJ; CONNEY, AH | 2 |
| HAHN, G; PATT, P; UEBEL, H; VOGEL, G | 1 |
| ZAKHARIIA, EA; ZAPADNIUK, VI | 1 |
| REMMER, H; SIEGERT, M | 1 |
| CRAM, RL; FOUTS, JR; JUCHAU, MR | 1 |
| ADAMSON, RH; FOUTS, JR; HART, LG; MORRIS, HP | 1 |
| Laczay, P; Monostory, K; Szucs, G; Tamási, V | 1 |
| Kicha, LP; Strickhart, FS; Yang, CS | 1 |
| Hu, K; Li, D; Lin, M; Yang, XL; Yu, WJ; Zhang, SJ | 1 |
| TANAY, I | 1 |
6 review(s) available for phenobarbital and aminopyrine
| Article | Year |
|---|---|
Mixed function oxidation and intermediary metabolism: metabolic interdependencies in the liver.
Topics: Aminopyrine; Animals; Biotransformation; Dihydroxyacetone; Gluconeogenesis; Glucose; Lactates; Lipids; Liver; NADP; Nitroanisole O-Demethylase; Oxidation-Reduction; Oxygen Consumption; Phenobarbital; Rats; Tritium; Water | 1975 |
[Ultramicroscopic pathology of the liver].
Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Bile; Cytoplasm; Glucose; Humans; Hypoxia; Lipoproteins; Liver; Liver Diseases; Methylcholanthrene; Microscopy, Electron; Oxidative Phosphorylation; Phenobarbital; Proteins; Rats; Water | 1968 |
Current trends in hepatic response tests.
Topics: Aminopyrine; Animals; Ascorbic Acid; Circadian Rhythm; Cold Temperature; Cytochromes; DDT; Dietary Carbohydrates; Dietary Proteins; Dogs; Enzyme Induction; Guinea Pigs; Hepatomegaly; Hexobarbital; Humans; Hydrocarbons; Liver; Mice; Microsomes, Liver; NADP; Organ Size; Phenobarbital; Rabbits; Rats | 1969 |
The nutritional and metabollic roles of selenium and vitamin E.
Topics: Aminopyrine; Animals; Antioxidants; Endoplasmic Reticulum; Glutathione; Iron; Membranes; Metalloproteins; Microsomes, Liver; Mitochondria; Oxidation-Reduction; Peroxidases; Peroxides; Phenobarbital; Selenium; Species Specificity; Vitamin E; Vitamin E Deficiency | 1974 |
[Anti-dysmenorrhea drugs. 17].
Topics: Aminopyrine; Amphetamine; Analgesics; Aspirin; Atropa belladonna; Codeine; Dysmenorrhea; Ergot Alkaloids; Ergotamine; Esters; Ethinyl Estradiol; Female; Glycine; Hormones; Humans; Hypnotics and Sedatives; Methyltestosterone; Muscles; Papaverine; Phenacetin; Phenobarbital; Phytotherapy; Plants, Medicinal; Plants, Toxic; Quinine; Salicylamides | 1967 |
THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM.
Topics: Aminopyrine; Chloramphenicol; Coumarins; Dicumarol; Humans; Metabolism; Pharmaceutical Preparations; Pharmacology; Phenacetin; Phenobarbital; Phenylbutazone | 1964 |
3 trial(s) available for phenobarbital and aminopyrine
| Article | Year |
|---|---|
Evaluation of in vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo.
Topics: 17-Hydroxycorticosteroids; Adult; Aminopyrine; Clinical Trials as Topic; Drug Evaluation; Enzyme Induction; gamma-Glutamyltransferase; Glucaric Acid; Half-Life; Humans; Hydrocortisone; Kinetics; Male; Phenobarbital; Placebos | 1975 |
[Comparison of the effects of phenylbutazone and a combination preparation (Exrheudon) in rheumatic diseases].
Topics: Aminopyrine; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Dipyrone; Drug Combinations; Drug Evaluation; Female; Humans; Male; Middle Aged; Phenobarbital; Phenylbutazone; Rheumatic Diseases | 1977 |
[Experience with the use of new Bulgarian psychotropic drugs].
Topics: Adolescent; Adult; Aminopyrine; Aminoquinolines; Child; Clinical Trials as Topic; Depression; Dipyrone; Drug Combinations; Epilepsy; Female; Humans; Male; Mental Disorders; Middle Aged; Phenobarbital; Piperidines; Piperidones; Procyclidine; Psychotropic Drugs; Pyrrolidines; Substance Withdrawal Syndrome; Syndrome | 1982 |
252 other study(ies) available for phenobarbital and aminopyrine
| Article | Year |
|---|---|
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds.
Topics: Anti-Inflammatory Agents; Cell Membrane Permeability; Cluster Analysis; Drug Evaluation, Preclinical; Humans; Models, Biological; Predictive Value of Tests; Quantitative Structure-Activity Relationship; Regression Analysis; Skin; Skin Absorption | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Properties of glutathione release observed during reduction of organic hydroperoxide, demethylation of aminopyrine and oxidation of some substances in perfused rat liver, and their implications for the physiological function of catalase.
Topics: Aminopyrine; Animals; Benzylamines; Catalase; Cell Separation; Glutathione; Glutathione Peroxidase; Glycolates; Liver; Male; Mitochondria, Liver; NADP; Nucleotides; Oxidation-Reduction; Perfusion; Peroxides; Phenobarbital; Rats; Triazoles; Uric Acid | 1977 |
Developmental aspects of xenobiotic transformation.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Ethylmorphine; Female; Glucosephosphates; Hexobarbital; Hydrogen-Ion Concentration; Metyrapone; Microsomes, Liver; NAD; NADP; Niacinamide; Oxidoreductases, N-Demethylating; Oxidoreductases, O-Demethylating; Phenobarbital; Pregnancy; Rats; Semicarbazides | 1976 |
Respiratory activity of Ehrlich ascites tumour cell nuclei.
Topics: Aminopyrine; Animals; Antimycin A; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytochrome Reductases; Cytochromes; Electron Transport; Endoplasmic Reticulum; Enzyme Induction; Mice; Microsomes; Mitochondria; NAD; Oxygen Consumption; Phenobarbital; Rotenone | 1975 |
The properties of hydrogen peroxide production under hyperoxic and hypoxic conditions of perfused rat liver.
Topics: Aminopyrine; Animals; Body Weight; Catalase; Cytochrome c Group; Ethanol; Glycolates; Hydrogen Peroxide; Hyperbaric Oxygenation; Hypoxia; Lactates; Liver; Male; Microsomes, Liver; Oxidation-Reduction; Oxygen; Perfusion; Phenobarbital; Pyruvates; Rats; Starvation; Urate Oxidase | 1975 |
Interaction between microsomal electron transfer pathways.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Cytochrome Reductases; Cytochromes; Electron Transport; Ethylmorphine-N-Demethylase; Fatty Acids; Hexobarbital; Lipid Metabolism; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Peroxidases; Phenobarbital; Rats; Spectrum Analysis; Stearoyl-CoA Desaturase | 1975 |
Comparison of methods to study enzyme induction in man.
Topics: 17-Hydroxycorticosteroids; Acetates; Adipates; Adult; Amines; Aminopyrine; Antipyrine; Biotransformation; Clemastine; Enzyme Induction; gamma-Glutamyltransferase; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Phenobarbital; Sugar Acids | 1975 |
The dependence on vitamin E and selenium of drug demethylation in rat liver microsomal fractions.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Antioxidants; Castration; Dietary Proteins; Electron Transport; Haplorhini; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Selenium; Time Factors; Vitamin E; Vitamin E Deficiency | 1975 |
Application of Gran's potentiometric method in pharmaceutical analysis.
Topics: Acid-Base Equilibrium; Aminopyrine; Chemistry, Pharmaceutical; Codeine; Hydrogen-Ion Concentration; Morphine Derivatives; Phenobarbital; Potentiometry | 1975 |
Hepatic drug metabolism in normal and vitamin E-deficient female Merino sheep.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Body Weight; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Enzyme Induction; Female; In Vitro Techniques; Liver; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Nitrobenzoates; Organ Size; Pharmaceutical Preparations; Phenobarbital; Rats; Sheep; Species Specificity; Vitamin E Deficiency | 1977 |
Inhibition of hepatic demethylation of aminopyrine by oral contraceptive steroids in humans.
Topics: Adult; Aminopyrine; Breath Tests; Contraceptives, Oral; Contraceptives, Oral, Hormonal; Dimethylamines; Female; Half-Life; Humans; Liver; Male; Phenobarbital | 1978 |
[Amidopyrene (aminophenazone) elimination curve as an indicator of enzymatic induction of the endoplasmic reticulum in perfused rat liver].
Topics: Aminopyrine; Animals; Drug Interactions; Endoplasmic Reticulum; Enzyme Induction; Liver; Male; Phenobarbital; Prednisone; Rats | 1979 |
Breath analysis of 14CO2 production from aminopyrine in the normal rat.
Topics: Aminopyrine; Animals; Breath Tests; Carbon Dioxide; Disulfiram; Fasting; Male; Phenobarbital; Proadifen; Rats; Time Factors; Tissue Distribution | 1979 |
The effect of dietary fats on the composition of the liver endoplasmic reticulum and oxidative drug metabolsim.
Topics: Aminopyrine; Animals; Dietary Fats; Endoplasmic Reticulum; Fatty Acids; Linoleic Acids; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Vitamin E | 1979 |
Methionine and thyroid hormone effects on 14CO2 exhalation from [dimethylamino-14C]aminopyrine in intact phenobarbital-pretreated rats.
Topics: Aminopyrine; Animals; Carbon Dioxide; Carbon Radioisotopes; Male; Methionine; Phenobarbital; Rats; Respiration; Thyroidectomy; Thyroxine | 1979 |
Decreased hepatic microsomal reserve in patients with cirrhosis. Studies using aminopyrine as model drug.
Topics: Adult; Aminopyrine; Antipyrine; Female; Humans; Liver Cirrhosis, Alcoholic; Male; Microsomes, Liver; Middle Aged; Phenobarbital; Spironolactone | 1979 |
A new organ spectrophotometer for sensitive dual-wavelength absorbance measurement and spectral scanning of intact perfused organs.
Topics: Aminopyrine; Animals; Cyanides; Liver; Perfusion; Phenobarbital; Rats; Spectrometry, Fluorescence; Spectrophotometry | 1978 |
Glutathione efflux from perfused rat liver after phenobarbital treatment, during drug oxidations, and in selenium deficiency.
Topics: Aminopyrine; Animals; Dose-Response Relationship, Drug; Ethylmorphine; Glutathione; Hexobarbital; L-Lactate Dehydrogenase; Liver; Male; Oxidation-Reduction; Perfusion; Phenobarbital; Rats; Selenium | 1978 |
Effect of gum Arabic on aminopyrine demethylation in rats.
Topics: Acacia; Aminopyrine; Animals; Dealkylation; Excipients; Female; Pharmaceutical Vehicles; Phenobarbital; Polysaccharides; Rats | 1978 |
Alterations in the toxicity of thiodemeton due to the pretreatment of inducers, substrates and inhibitors of mixed function oxidase system.
Topics: Acetanilides; Aminopyrine; Animals; Cobalt; Cycloheximide; Disulfoton; Enzyme Induction; Ethylmorphine; Female; Insecticides; Male; Methylcholanthrene; Mixed Function Oxygenases; Nickel; Oxidoreductases; Phenobarbital; Rats | 1978 |
Cytochrome P-450 and drug metabolism in Trypanosoma cruzi: effects of phenobarbital.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Cytochrome P-450 Enzyme System; Metyrapone; Microsomes; Mixed Function Oxygenases; Oxidoreductases, O-Demethylating; Phenobarbital; Proadifen; Ribosomes; Trypanosoma cruzi | 1976 |
Relationship between microsomal hydroxylase and glucuronyltransferase.
Topics: Aminopyrine; Animals; Bilirubin; Biotransformation; Chloramphenicol; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Female; Glucuronosyltransferase; Hexosyltransferases; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Naphthols; Nitrophenols; Phenobarbital; Polyethylene Glycols; Rats; Sex Factors; Sonication | 1975 |
Acute toxicity of substrates of the mixed function oxidase system in normal and phenobarbital-pretreated mice.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Aniline Hydroxylase; Animals; Antipyrine; Cytochrome P-450 Enzyme System; Ethylmorphine-N-Demethylase; Glucuronosyltransferase; Lethal Dose 50; Liver; Male; Mice; Mice, Inbred Strains; Mixed Function Oxygenases; Morphine Derivatives; NADPH-Ferrihemoprotein Reductase; Nitrophenols; Oxidoreductases; Phenobarbital | 1975 |
Hepatic drug metabolism and lipid peroxidation in thiamine deficient rats.
Topics: Acetanilides; Aminopyrine; Aniline Compounds; Animals; Biotransformation; Body Weight; Cytochromes; Electron Transport; Female; Heme; Inactivation, Metabolic; Lipid Metabolism; Liver; Male; Microsomes, Liver; Morphine Derivatives; NADPH-Ferrihemoprotein Reductase; Organ Size; Oxidation-Reduction; Phenobarbital; Rats; Thiamine Deficiency | 1976 |
Thioacetamide-induced hepatic necrosis. I. Involvement of the mixed-function oxidase enzyme system.
Topics: Acetamides; Aminopyrine; Aniline Compounds; Animals; Chemical and Drug Induced Liver Injury; Drug Interactions; Liver; Liver Diseases; Male; Mixed Function Oxygenases; Necrosis; Oxidoreductases; Phenobarbital; Rats; Sulfonium Compounds; Thioacetamide; Time Factors | 1977 |
Studies on aminophenazone and phenobarbital release from suppositories prepared on different bases.
Topics: Aminopyrine; Diffusion; Excipients; Membranes, Artificial; Phenobarbital; Suppositories; Time Factors | 1976 |
The effect of phenobarbital on biliary lipid metabolism and hepatic microsomal drug metabolism in patients with cholesterol cholelithiasis.
Topics: Adult; Aged; Aminopyrine; Bile; Bile Acids and Salts; Cholelithiasis; Cholesterol; Female; Humans; Kinetics; Lipid Metabolism; Male; Microsomes, Liver; Middle Aged; Phenobarbital | 1976 |
[Interaction of psychotropic and anticonvulsive drugs].
Topics: Aminopyrine; Animals; Chlordiazepoxide; Chlorpromazine; Cytochrome P-450 Enzyme System; DNA; Hexobarbital; Imipramine; Liver; Male; Microsomes, Liver; Phenobarbital; Proteins; Rats; RNA | 1976 |
Enzyme induction by repeated adminstration of tetrachlorvinphos in rats.
Topics: Aminopyrine; Animals; Cholinesterases; Dealkylation; Enzyme Induction; In Vitro Techniques; Inactivation, Metabolic; Insecticides; Male; Microsomes, Liver; Phenobarbital; Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester; Proadifen; Rats; Tetrachlorvinphos; Time Factors | 1976 |
Drug metabolism in the rabbit lung during pregnancy and in the perinatal period.
Topics: Aminopyrine; Animals; Female; Liver; Lung; Oxazepam; Phenobarbital; Pregnancy; Pregnancy, Animal; Rabbits | 1975 |
Energy wastage in rats given drugs that induce microsomal enzymes.
Topics: Aminopyrine; Animals; Barbiturates; Body Weight; Energy Metabolism; Enzyme Induction; Ethanol; Female; Hexobarbital; Male; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Rats | 1975 |
Studies on the metabolism of dimethylnitrosamine in the rat. II. The effects of phenobarbitone and 20-methylcholanthrene on the in vitro and in vivo metabolism and acute toxicity of dimethylnitrosamine in young and mature rats.
Topics: Age Factors; Aminopyrine; Aniline Hydroxylase; Animals; Carbon Dioxide; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ethylmorphine-N-Demethylase; Female; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Rats; Sex Factors | 1975 |
Expiratory measurement of maximal amino-pyrine demethylation in vivo: effect of phenobarbital, partial hepatectomy, protacaval shunt and bile duct ligation in the rat.
Topics: Aminopyrine; Animals; Bile Ducts; Body Weight; Carbon Dioxide; Hepatectomy; Kinetics; Liver; Male; Organ Size; Phenobarbital; Portacaval Shunt, Surgical; Rats; Time Factors | 1976 |
How the potency of the steroid RU486 is related to P450 activities induced by dexamethasone and phenobarbital in rat hepatoma cells.
Topics: Aminopyrine; Animals; Biotransformation; Cell Line; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Kinetics; Liver Neoplasms, Experimental; Male; Microsomes, Liver; Mifepristone; Phenobarbital; Rats; Rats, Inbred Strains | 1992 |
[Induction of cytochrome P-450 by triterpensaponins in Vietnamese ginseng].
Topics: Aminopyrine; Animals; Benzo(a)pyrene; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Saponins; Triterpenes | 1991 |
[Application of convolution curve method for simultaneous determination of four components in somidon].
Topics: Aminopyrine; Analgesics; Caffeine; Drug Combinations; Methods; Phenacetin; Phenobarbital; Tablets | 1990 |
Phenobarbital influences the development of sodium retention in liver disease induced by bile duct ligation in the rat.
Topics: Aminopyrine; Animals; Bile Ducts; Breath Tests; Creatinine; Ligation; Liver Cirrhosis, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Sodium | 1990 |
High performance liquid chromatographic determinations of khellin, phenobarbitone and dipyrone combination in tablets.
Topics: Aminopyrine; Chromatography, High Pressure Liquid; Dipyrone; Drug Combinations; Indicators and Reagents; Khellin; Phenobarbital; Spectrophotometry, Ultraviolet; Tablets | 1990 |
Demonstration of H2O2 production in vivo during aminopyrine metabolism and phenobarbital induction.
Topics: Aminopyrine; Amitrole; Animals; Antipyrine; Catalase; Cytochrome P-450 Enzyme System; Guinea Pigs; Hydrogen Peroxide; Male; Methanol; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Studies on the metabolism of aminopyrine, antipyrine and theophylline using monoclonal antibodies to cytochrome P-450 isozymes purified from rat liver.
Topics: Aminopyrine; Animals; Antibodies, Monoclonal; Antibody Specificity; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Activation; Epitopes; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Theophylline | 1987 |
[Treatment of vertebrogenic lumbosacral radiculitis and lumbar ischialgia by transcutaneous-cavitary electrophoresis of drugs].
Topics: Administration, Rectal; Adult; Aminopyrine; Back Pain; Colon, Sigmoid; Dexamethasone; Diphenhydramine; Dipyrone; Drug Therapy, Combination; Female; Humans; Indomethacin; Iontophoresis; Lumbosacral Region; Male; Middle Aged; Phenobarbital; Prednisolone; Procaine; Radiculopathy | 1989 |
Brief maternal deprivation of rats reduces hepatic mixed function oxidase activities.
Topics: Aminopyrine; Animals; Benzphetamine; Biotransformation; Body Weight; Coumarins; Enzyme Induction; Female; Handling, Psychological; Male; Maternal Deprivation; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Phenobarbital; Rats; Rats, Inbred Strains | 1989 |
[Rate of microsomal protein metabolism in the mouse liver].
Topics: Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Half-Life; Kinetics; Mice; Mice, Inbred C57BL; Microsomes, Liver; Phenobarbital; Proteins | 1989 |
[The effect of phenobarbital and amidopyrine on the rate of decomposition of isoforms of cytochrome P-450 in mouse liver microsomes].
Topics: Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Half-Life; Isoenzymes; Mice; Microsomes, Liver; Phenobarbital | 1989 |
Effect of repeated administration of monomethyl-aminoantipyrine on the activities of gamma-glutamyltranspeptidase and microsomal drug metabolizing enzymes in rat liver.
Topics: Aminopyrine; Animals; Body Weight; Cytochrome P-450 Enzyme System; Dipyrone; gamma-Glutamyltransferase; In Vitro Techniques; Kidney; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Proteins; Pyrazolones; Rats; Rats, Inbred Strains | 1985 |
Relation between biliary glutathione excretion and bile acid-independent bile flow.
Topics: Aminopyrine; Animals; Arsenic; Arsenites; Benzylamines; Bile; Bile Acids and Salts; Buthionine Sulfoximine; Cefamandole; Furosemide; Glutathione; Glycocholic Acid; Kinetics; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Nitrofurantoin; Phenobarbital; Rats; Rats, Inbred Strains; Sodium Compounds; Taurocholic Acid | 1989 |
Effect of inhibitors of alpha-naphthylisothiocyanate-induced hepatotoxicity on the in vitro metabolism of alpha-naphthylisothiocyanate.
Topics: 1-Naphthylisothiocyanate; Administration, Oral; Aminopyrine; Animals; Bilirubin; Biotransformation; Chromatography, Gas; Ditiocarb; Ethionamide; Hyperbilirubinemia; Imidazoles; Kinetics; Male; Methimazole; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Thiocyanates | 1985 |
Influence of phenobarbital on the hepatic handling of [3H]vitamin D3 in the dog.
Topics: Aminopyrine; Animals; Breath Tests; Calcifediol; Carbon Dioxide; Cholecalciferol; Cytochrome P-450 Enzyme System; Dogs; Enzyme Induction; Female; Kinetics; Liver; Phenobarbital | 1986 |
Diabetes alters drug metabolism--in vivo studies in a streptozotozin-diabetic rat model.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Diabetes Mellitus, Experimental; Female; Kinetics; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors | 1986 |
Metabolism of diamantane by rat liver microsomal cytochromes P-450.
Topics: Adamantane; Aminopyrine; Animals; Chromatography, Gas; Cytochrome P-450 Enzyme System; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1988 |
[Application of dynamic programming for quantitative analysis of qutong tablet and keganmin tablet].
Topics: Aminopyrine; Caffeine; Drug Combinations; Mathematics; Methods; Phenacetin; Phenobarbital; Tablets | 1988 |
Granulomatous lung disease in children by aspiration of medications.
Topics: Administration, Oral; Aminopyrine; Child; Cholestyramine Resin; Female; Foreign-Body Reaction; Granuloma; Humans; Hydroxybenzoates; Infant; Infant, Newborn; Lung; Male; Nitrofurans; Phenobarbital; Phenytoin; Pneumonia, Aspiration | 1987 |
Aminopyrine metabolism by multiple forms of cytochrome P-450 from rat liver microsomes: simultaneous quantitation of four aminopyrine metabolites by high-performance liquid chromatography.
Topics: Aminopyrine; Ampyrone; Animals; Antipyrine; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dipyrone; Female; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Phenobarbital; Pyrazolones; Rats; Rats, Inbred Strains | 1988 |
[Metabolic characteristics of xenobiotics in the liver of tumor-bearing rats].
Topics: Aminopyrine; Aniline Compounds; Aniline Hydroxylase; Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzyme Induction; Hydroxylation; Liver Neoplasms, Experimental; Lymphoma, Non-Hodgkin; Male; Microsomes, Liver; Neoplasm Transplantation; Phenobarbital; Rats; Time Factors | 1987 |
[Liver cytochrome P-450 induction in rats by drug preparations and the body vitamin A allowance].
Topics: Aminopyrine; Animals; Body Weight; Cytochrome P-450 Enzyme System; Drug Combinations; Enzyme Induction; Liver; Male; Organ Size; Phenobarbital; Phenylbutazone; Rats; Vitamin A | 1987 |
Lipid composition of liver microsomes from rats treated with acetone.
Topics: Acetone; Acetonitriles; Administration, Oral; Aminopyrine; Animals; Cholesterol; Cytochrome P-450 Enzyme System; Female; Microsomes, Liver; Phenobarbital; Phospholipids; Rats; Rats, Inbred Strains | 1986 |
Effect of suicide substrate on the metabolism of steroids and xenobiotics and on cytochrome P-450 apoproteins.
Topics: Aminopyrine; Animals; Apoproteins; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dicarbethoxydihydrocollidine; Formaldehyde; Formates; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphine; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains; Testosterone | 1986 |
o,p'-DDD in the mouse lung: selective uptake, covalent binding and effect on drug metabolism.
Topics: Adipose Tissue; Adrenal Glands; Aminopyrine; Animals; Autoradiography; Benzoflavones; beta-Naphthoflavone; DDT; Dose-Response Relationship, Drug; Isomerism; Liver; Lung; Maleates; Metyrapone; Mice; Mice, Inbred C57BL; Mitotane; Phenobarbital; Pulmonary Alveoli | 1986 |
Correlation between the metabolism of hexobarbital and aminopyrine in vivo in rats.
Topics: Administration, Oral; Aminopyrine; Animals; Aroclors; Carbon Tetrachloride; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Hexobarbital; Isoenzymes; Liver; Male; Metabolic Clearance Rate; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred Strains | 1986 |
Interrelationship between aminopyrine oxidation and gluconeogenesis in hepatocytes prepared from fructose-pretreated mice.
Topics: Aminopyrine; Animals; Cells, Cultured; Cytochrome P-450 Enzyme System; Formaldehyde; Fructose; Gluconeogenesis; Hexobarbital; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Oxidation-Reduction; Phenobarbital | 1987 |
[Linear titration of weakly alkaline drugs].
Topics: Alkalies; Aminopyrine; Amobarbital; Benzoates; Benzoic Acid; Hydrogen-Ion Concentration; Mathematics; Microcomputers; Phenobarbital; Solubility; Water | 1985 |
Influence of pyrazolones on hepatic glutathione in rats.
Topics: 1-Propanol; Acetaminophen; Aminopyrine; Animals; Antipyrine; Carbon Tetrachloride; Cobalt; Female; Glutathione; Liver; Phenobarbital; Propanols; Pyrazoles; Rats; Rats, Inbred Strains; Thioacetamide | 1985 |
Biphasic effect of pyrazolone derivatives on drug-metabolizing enzyme in rat liver.
Topics: Aminopyrine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Biotransformation; Cytochrome P-450 Enzyme System; Dealkylation; Female; Hexobarbital; Liver; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors | 1985 |
[Effect of amidopyrine on the rate of cytochrome P-450 isoform breakdown].
Topics: Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Half-Life; Isomerism; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxygenases; Phenobarbital; Proteins; Substrate Specificity; Time Factors | 1986 |
[Structural-functional aspects of the postischemic recovery of the hepatocyte endoplasmic network in rats].
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Endoplasmic Reticulum; Ischemia; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors | 1986 |
[Transplacental effect of sodium nitrite on rat lung cells with their subsequent culture in the medium with precursors of N-nitrosodimethylamine].
Topics: Aminopyrine; Animals; Ascorbic Acid; Cell Survival; Culture Media; Dimethylnitrosamine; Drug Synergism; Female; Fetus; In Vitro Techniques; Lung; Maternal-Fetal Exchange; Mitosis; Nitrites; Phenobarbital; Pregnancy; Pregnancy, Animal; Rats; Sodium Nitrite; Vitamin E | 1985 |
Hepatic amidopyrine N-demethylase activity in the calf.
Topics: Aminopyrine; Animals; Arginase; Aspartate Aminotransferases; Bilirubin; Carbon Tetrachloride; Cattle; Centrifugation; Deoxyribonucleases; Female; Halothane; Liver; Naphthalenes; Oxidoreductases; Phenobarbital; Staining and Labeling; Time Factors | 1972 |
Oxidative drug metabolism in the perinatal rabbit liver and placenta. A biochemical and morphologic study.
Topics: Aminopyrine; Animals; Animals, Newborn; Benzopyrenes; Cytochrome Reductases; Electron Transport; Endoplasmic Reticulum; Female; Gestational Age; Hydroxylation; Liver; Methylation; Microscopy, Electron; Microsomes; Microsomes, Liver; NAD; NADP; Phenobarbital; Placenta; Pregnancy; Rabbits; Species Specificity | 1973 |
Glutarimide antibiotics and drug metabolism in the rat.
Topics: Aminopyrine; Animals; Anti-Bacterial Agents; Azo Compounds; Cyclohexanes; Cycloheximide; Dealkylation; Female; In Vitro Techniques; Microsomes, Liver; Naphthalenes; Oxidation-Reduction; Phenobarbital; Piperidones; Protein Biosynthesis; Rats; Sulfonamides; Sulfonic Acids | 1973 |
Electron transport components of hepatic microsomes. Solubilization, resolution, and recombination to reconstitute aniline hydroxylase activity.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Chloromercuribenzoates; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Phenobarbital; Rats; Solubility; Structure-Activity Relationship; Vitamin K | 1973 |
Possible control of hydrogen peroxide production and degradation in microsomes during mixed function oxidation reaction.
Topics: Aminopyrine; Animals; Azides; Catalase; Cytochrome P-450 Enzyme System; Hemeproteins; Hydrogen Peroxide; Hydroxylation; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Pregnenolone Carbonitrile; Rats; Time Factors | 1973 |
Interaction of mixed-function oxidation with biosynthetic processes. 1. Inhibition of gluconeogenesis by aminopyrine in perfused rat liver.
Topics: Acetone; Aminopyrine; Animals; Depression, Chemical; Flavins; Fluorometry; Gluconeogenesis; In Vitro Techniques; Kinetics; Lactates; Liver; Male; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Perfusion; Phenobarbital; Rats | 1973 |
Lipid peroxidation and the degradation of cytochrome P-450 heme.
Topics: Aminopyrine; Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Levulinic Acids; Lipid Metabolism; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Pentobarbital; Peroxidases; Phenobarbital; Protein Binding; Rats; Secobarbital; Spectrophotometry; Time Factors; Tritium | 1973 |
Riboflavin and drug metabolism in adult male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Biotransformation; Body Weight; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Diet; Electron Transport; Female; In Vitro Techniques; Liver; Male; Microsomes, Liver; Morphinans; NADP; Organ Size; Phenobarbital; Proteins; Rats; Riboflavin Deficiency; Sex Factors; Time Factors | 1974 |
[Obtaining microsomes by coprecipitation with Ca2+ and demonstration of enzyme induction using phenobarbital].
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Butylated Hydroxytoluene; Cytological Techniques; Enzyme Induction; Glucosephosphates; Liver; Male; Microsomes; NADP; Oxidoreductases; Phenobarbital; Rats | 1973 |
The effect of ethchlorvynol on the drug-metabolizing enzymes of rats and dogs.
Topics: Aminopyrine; Animals; Dicumarol; Dogs; Ethchlorvynol; Glutethimide; Hypnotics and Sedatives; Liver; Microsomes; NADP; Phenobarbital; Rats | 1967 |
[Pathomechanic variants of allergic drug induced skin injuries].
Topics: Allergens; Aminopyrine; Dermatitis, Contact; Drug Eruptions; Drug Hypersensitivity; Exanthema; Female; Humans; Hypnotics and Sedatives; Iodine; Male; Penicillins; Phenobarbital; Quinine; Skin; Sulfamethoxypyridazine; Urticaria | 1969 |
Drug metabolism by hepatic microsomes from phenobarbital-treated or starved male and female rats in the presence of inhibitors.
Topics: Aminopyrine; Aniline Compounds; Animals; Cytochromes; Female; Hexobarbital; Liver; Male; Methylation; Microsomes, Liver; Morphinans; Niacinamide; Organ Size; Phenobarbital; Proadifen; Rats; Starvation | 1971 |
Studies on the irreversible binding of 14 C-CCl 4 to microsomal lipids in rats under varying experimental conditions.
Topics: Adrenal Glands; Adrenalectomy; Aminopyrine; Animals; Carbon Isotopes; Carbon Tetrachloride; Castration; Centrifugation, Density Gradient; Edetic Acid; Ethylamines; Gonads; Hydroxylation; Lipid Metabolism; Liver; Male; Malonates; Microsomes, Liver; Niacinamide; Phenobarbital; Phenols; Proadifen; Rats; Sleep; Sucrose | 1972 |
Active centers of microsomal cytochrome P-450 determined with metyrapone by mutural depletion system kinetics.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Catalysis; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Morphinans; Morphine; Oxidoreductases, N-Demethylating; Phenobarbital; Protein Binding; Rats | 1973 |
Proceedings: Evaluation of induction of drug metabolizing enzyme activities in man by different in vivo tests.
Topics: 17-Hydroxycorticosteroids; Adult; Aminopyrine; Enzyme Induction; Enzymes; Humans; Hydrocortisone; Male; Pharmaceutical Preparations; Phenobarbital | 1974 |
Effects of steroid hormones on drug-metabolizing enzyme systems in liver microsomes.
Topics: Adenosine Triphosphatases; Aminopyrine; Aniline Compounds; Animals; Dihydrolipoamide Dehydrogenase; Esterases; Glucose-6-Phosphatase; Hydrocortisone; Liver; Mice; Microsomes; Mixed Function Oxygenases; Phenobarbital; Prednisolone; Rats; Spectrophotometry | 1968 |
Biochemical changes in rat liver in response to treatment with drugs and other agents. I. Effects of anticonvulsant, anti-inflammatory, hypocholesterolaemic and adrenergic beta-blocking agents.
Topics: Acetanilides; Aminopyrine; Animals; Anti-Inflammatory Agents; Anticholesteremic Agents; Anticonvulsants; Barbiturates; Body Weight; Butyrates; Cytochromes; Cytoplasm; Electron Transport; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Glutamate Dehydrogenase; Indomethacin; L-Lactate Dehydrogenase; Liver; Male; Microsomes; Organ Size; Oxidoreductases; Phenobarbital; Phenylbutazone; Phenytoin; Phosphogluconate Dehydrogenase; Propranolol; Proteins; Rats; Sympatholytics | 1969 |
Further observations on hepatic drug metabolism in rats treated with a mixture of somatotropin, corticotropin and prolactin.
Topics: Adrenocorticotropic Hormone; Aminopyrine; Animals; Growth Hormone; Hexobarbital; Liver; Male; Microsomes, Liver; Morphinans; Neoplasm Transplantation; Phenobarbital; Pituitary Neoplasms; Prolactin; Rats | 1969 |
[Effect of carbon tetrachloride on endoplasmic enzymes in rat liver].
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cholinesterases; Cytochromes; Endoplasmic Reticulum; Formaldehyde; Glucose-6-Phosphatase; Hexobarbital; Male; Membranes; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Protein Binding; Rabbits; Rats; Spectrophotometry | 1971 |
Effects in vitro and in vivo of methylenedioxyphenyl compounds on oxidative phosphorylation in rat liver mitochondria.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; Aldehydes; Allyl Compounds; Aminopyrine; Aniline Compounds; Animals; Cytochromes; Dealkylation; Dinitrophenols; Dioxoles; Electron Transport; Enzyme Activation; Ethers; Ethers, Cyclic; Glutamates; Hydroxybutyrates; Magnesium; Male; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NAD; Oxidative Phosphorylation; Oxidoreductases; Oxygen Consumption; Phenobarbital; Polarography; Rats; Succinate Dehydrogenase; Succinates; Uncoupling Agents | 1971 |
Non-competitive and competitive inhibition of mixed function oxidase in rat liver microsomes by metyrapone.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Binding Sites; Cytochrome P-450 Enzyme System; Electron Transport Complex IV; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Morphine; Oxidoreductases, N-Demethylating; Phenobarbital; Protein Binding; Rats | 1973 |
Energy coupling and extramitochondrial electron transport in slices of Morris hepatoma 3924 A.
Topics: Aminopyrine; Animals; Antimycin A; Biological Transport; Carcinoma, Hepatocellular; Cyanides; Dinitrophenols; Electrons; Liver Neoplasms; Mitochondria, Liver; Neoplasms, Experimental; Oligomycins; Ouabain; Oxygen Consumption; Phenobarbital; Rats; Rotenone; Succinates | 1974 |
[Comparative study on quantitative determination of mixtures of analgesics. 1. Studies on selectivity of volumetric analysis procedures].
Topics: Acetaminophen; Aminopyrine; Analgesics; Ascorbic Acid; Aspirin; Barbiturates; Caffeine; Chlorpromazine; Codeine; Conductometry; Electrochemistry; Meprobamate; Mesylates; Methods; Papaverine; Phenacetin; Phenobarbital; Phenylbutazone; Potentiometry; Quinine; Salicylamides; Salicylates; Theobromine | 1974 |
Phenobarbital-induced synthesis of the microsomal drug-metabolizing enzyme system and its relationship to the proliferation of endoplasmic membranes. A morphological and biochemical study.
Topics: Aminopyrine; Animals; Carbon Monoxide; Codeine; Dactinomycin; Endoplasmic Reticulum; In Vitro Techniques; Liver; Microscopy, Electron; Microsomes; NADP; Nitrosamines; Oxidoreductases; Phenobarbital; Pigments, Biological; Puromycin; Rats; Thyroidectomy; Triiodothyronine | 1965 |
Substrate interaction with hydroxylase system in liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Cyanides; Cytochromes; Guinea Pigs; In Vitro Techniques; Liver; Microsomes; Mixed Function Oxygenases; NADP; Phenacetin; Phenobarbital; Rabbits; Rats; Spectrophotometry | 1966 |
Possible role of P-450 in the oxidation of drugs in liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Carisoprodol; Chlorpromazine; Cytochromes; Glutethimide; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Oxidoreductases; Pentobarbital; Phenobarbital; Piperazines; Rats | 1966 |
Effect of phenobarbital treatment on the activities of NADPH-dependent enzymes of liver microsomes in fasting or sucrose-fed rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Isotopes; Female; Liver; Male; Microsomes; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Phenylalanine; Rats; Starvation; Sucrose | 1967 |
Some characteristics of hepatic microsomal systems which metabolize aminopyrine in the rat and rabbit.
Topics: Aminopyrine; Animals; Antipyrine; Chromatography, Thin Layer; Formaldehyde; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Microsomes; NADP; Oxygen; Phenobarbital; Rabbits; Rats | 1968 |
On the fatty acid and hydrocarbon hydroxylation in rat liver microsomes.
Topics: Alkanes; Aminopyrine; Animals; Carbon Monoxide; Cytochromes; Depression, Chemical; Fatty Acids; Fluorometry; Liver; Male; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Pigments, Biological; Rats; Stimulation, Chemical; Testosterone | 1968 |
Drug metabolism in tumor-bearing rats. I. Activities of NADPH-linked electron transport and drug-metabolizing enzyme systems in liver microsomes of tumor-bearing rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Barbiturates; Body Weight; Carcinoma 256, Walker; Carisoprodol; Cyclophosphamide; Electron Transport; Electron Transport Complex IV; Female; Liver; Male; Microsomes; Mixed Function Oxygenases; NADP; Organ Size; Oxidoreductases; Phenobarbital; Rats | 1968 |
The inhibitory effect of aureomycin (chlortetracycline) pretreatment on some rat liver microsomal enzyme activities.
Topics: Albumins; Aminopyrine; Animals; Body Weight; Chlortetracycline; Cytochromes; Depression, Chemical; Hexobarbital; Injections, Intraperitoneal; Liver; Magnesium; Male; Microsomes; NADP; Organ Size; Phenobarbital; Proteins; Rats; Sleep | 1969 |
Modification of parathion toxicity to wax moth larvae by chlorcyclizine, aminopyrine or phenobarbital.
Topics: Aminopyrine; Animals; Drug Tolerance; Histamine H1 Antagonists; Insecta; Parathion; Phenobarbital; Piperazines | 1969 |
Hydroxylation of benzphetamine and other drugs by a solubilized form of cytochrome P-450 from liver microsomes: lipid requirement for drug demethylation.
Topics: Aminopyrine; Animals; Appetite Depressants; Benzphetamine; Cytochromes; Depression, Chemical; Ethers; Fatty Acids; Formaldehyde; Hexobarbital; Lipid Metabolism; Liver; Microsomes; Mixed Function Oxygenases; Morphinans; NADP; Oxidoreductases; Phenethylamines; Phenobarbital; Propylamines; Rabbits; Spectrophotometry | 1969 |
Mixed function oxidation in perfused rat liver. The effect of aminopyrine on oxygen uptake.
Topics: Aminopyrine; Animals; Antimycin A; Cyanides; Depression, Chemical; Drug Synergism; Fasting; Fluorometry; Hemoglobins; In Vitro Techniques; Liver; Male; Microsomes, Liver; Mitochondria, Liver; Models, Biological; NADP; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Rats; Stimulation, Chemical; Time Factors | 1969 |
Effects of metyrapone on liver microsomal drug oxidations.
Topics: Acetanilides; Aminopyrine; Animals; Depression, Chemical; Hexobarbital; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Morphine; NADP; Phenobarbital; Rats; Sleep; Stimulation, Chemical; Trichloroethylene; Tyramine | 1969 |
Hepatic drug-metabolizing enzyme activity in rats pretreated with (-)-emetine or (plus or minus)-2,3-dehydroemetine.
Topics: Aminopyrine; Animals; Depression, Chemical; Drug Synergism; Emetine; Female; Glucosephosphate Dehydrogenase; Hexobarbital; Liver; Microsomes, Liver; NADP; Phenobarbital; Rats; Sulfonamides | 1970 |
Interaction of gluconeogenesis and mixed function oxidation.
Topics: Acetone; Aminopyrine; Animals; Gluconeogenesis; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; In Vitro Techniques; Lactates; Liver; Microsomes, Liver; NADP; Perfusion; Phenobarbital; Rats; Trioses | 1970 |
The influence of magnesium and some other divalent cations on hepatic microsomal drug metabolism in vitro.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Calcium; Chlorides; Cobalt; Copper; Cytochromes; Edetic Acid; Hexobarbital; In Vitro Techniques; Iron; Magnesium; Male; Manganese; Microsomes, Liver; NADP; Nitrophenols; Phenobarbital; Potassium; Rats; Strontium; Sulfates; Zinc; Zoxazolamine | 1970 |
Fatty acid inducible cy tochrome P-454 of rat kidney cortex microsomes.
Topics: Aminopyrine; Animals; Carbon Monoxide; Cytochromes; Dietary Fats; Electron Transport; Fatty Acids, Nonesterified; Kidney; Male; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry; Sulfites; Testosterone | 1970 |
Relationship between difference spectra and metabolism. Barbiturates, drug interaction and species difference.
Topics: Acetanilides; Acetates; Amino Alcohols; Aminopyrine; Aniline Compounds; Animals; Barbiturates; Binding Sites; Chemical Phenomena; Chemistry; Chlorpromazine; Cytochromes; Drug Antagonism; Drug Synergism; Ethanolamines; Hexobarbital; Macaca; Male; Mice; Microsomes, Liver; Pentobarbital; Phenobarbital; Proadifen; Propranolol; Protein Binding; Rats; Sleep; Species Specificity; Spectrophotometry; Thiazoles; Tremorine | 1970 |
The distinct nature and function of NADPH-cytochrome c reductase and the NADPH-dependent mixed-function amine oxidase of porcine liver microsomes.
Topics: Aminopyrine; Ammonium Sulfate; Aniline Compounds; Animals; Chemical Precipitation; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cross Reactions; Cytochromes; Electrophoresis; Electrophoresis, Disc; Female; Flavin-Adenine Dinucleotide; Flavoproteins; Immune Sera; Immunodiffusion; Lipase; Lipoprotein Lipase; Methylamines; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; Molecular Weight; Monoamine Oxidase; NADP; Oxidoreductases; Pancreas; Phenobarbital; Swine; Ultracentrifugation | 1971 |
A comparative study on the effects of phenobarbital and 3,4-benzpyrene on the hydroxylating enzyme system of rat-liver microsomes.
Topics: Aminopyrine; Animals; Benzopyrenes; Carbon Monoxide; Cytochromes; Enzyme Activation; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry | 1969 |
Immunochemical studies on the role of reduced nicotinamide adenine dinucleotide phosphate-cytochrome c (P-450) reductase in drug oxidation.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Cytochromes; Dealkylation; Immune Sera; Immunodiffusion; Immunoglobulins; Liver; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidative Phosphorylation; Oxidoreductases; Phenobarbital; Rabbits; Rats | 1971 |
Ascorbic acid and drug metabolism.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Ascorbic Acid; Ascorbic Acid Deficiency; Cytochromes; Fasting; Guinea Pigs; Kinetics; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitro Compounds; Oxidoreductases; Pharmaceutical Preparations; Phenobarbital; Spectrophotometry; Subcellular Fractions | 1972 |
Monooxygenase drug metabolizing activity in CaCl 2 -aggregated hepatic microsomes from rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Calcium Chloride; Carbon Monoxide; Chlorine; Dronabinol; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats | 1972 |
A comparison of mouse and rat liver enzymes and their response to treatment with various compounds.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Chlorpromazine; Clofibrate; Cytochromes; DDT; Germ-Free Life; Glucose-6-Phosphatase; Glucosephosphate Dehydrogenase; Griseofulvin; L-Lactate Dehydrogenase; Liver; Mice; NAD; NADP; Organ Size; Oxidoreductases; Phenobarbital; Phosphogluconate Dehydrogenase; Rats; Species Specificity | 1972 |
Influence of dietary iron levels on hepatic drug metabolism in vivo and in vitro in the rat.
Topics: Aminopyrine; Anemia, Hypochromic; Aniline Compounds; Animals; Body Weight; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Diet; Half-Life; Hematocrit; Hemoglobins; In Vitro Techniques; Iron; Liver; Male; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Proteins; Rats | 1972 |
In vitro activation of isophosphamide (NSC-109724), a new oxazaphosphorine, by rat liver microsomes.
Topics: Alkylating Agents; Alkylation; Aminopyrine; Aniline Compounds; Animals; Cyclic P-Oxides; Cyclophosphamide; Dealkylation; DNA; Enzyme Activation; Ethylamines; Kinetics; Liver; Male; Microsomes, Liver; Morphinans; NADP; Oxazines; Oxidoreductases; Phenobarbital; Phosphoranes; Proadifen; Proteins; Rats; RNA | 1972 |
[Micro-method for the quantitative determination of sedatives and antipyretics (aminophenazone, diphenylhydantoin, paracetamol, phenobarbital, primidone) using thermo-gas chromatography].
Topics: Acetaminophen; Aminopyrine; Analgesics; Chromatography, Gas; Hypnotics and Sedatives; Methods; Microchemistry; Phenobarbital; Phenytoin; Primidone; Temperature | 1974 |
Vitamin E, steroids, and liver microsomal hydroxylations.
Topics: Adrenal Glands; Adrenalectomy; Age Factors; Aminopyrine; Aniline Compounds; Animals; Castration; Codeine; Corticosterone; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Hemeproteins; Hydrocortisone; Hydroxycorticosteroids; Hydroxylation; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rabbits; Rats; Sex Factors; Species Specificity; Testis; Testosterone; Vitamin E; Vitamin E Deficiency | 1974 |
Assessment of aminopyrine metabolism in man by breath analysis after oral administration of 14C-aminopyrine. Effects of phenobarbital, disulfiram and portal cirrhosis.
Topics: Administration, Oral; Adult; Aged; Alcoholism; Aminopyrine; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Disulfiram; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Phenobarbital; Serum Albumin; Syndrome | 1974 |
[Influence of phenobarbital on drug metabolizing enzymes in the human placenta, on the fine structure of the chorionic villi and on the serum bilirubin concentration in the newborn infants].
Topics: Aminopyrine; Bilirubin; Codeine; Enzyme Induction; Extraembryonic Membranes; Female; Humans; Infant, Newborn; Microscopy, Electron; Mixed Function Oxygenases; Phenobarbital; Placenta; Pregnancy | 1972 |
Differences in microsomal enzyme induction between Sprague-Dawley and Long-Evans rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Antipyrine; Brain Chemistry; DDT; Enzyme Induction; Eucalyptus; Female; Liver; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenols; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Sleep | 1972 |
Some factors affecting liver microsomal drug metabolism in the chicken.
Topics: Aminopyrine; Animals; Chick Embryo; Chickens; Emetine; Enzyme Induction; Liver; Microsomes, Liver; Naphthalenes; Phenobarbital | 1972 |
Effect of phenobarbital and naphthalene on some of the components of the electron transport system and the hydroxylating activity of house fly microsomes.
Topics: Aminopyrine; Animals; Binding Sites; Binding, Competitive; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Enzyme Induction; Female; Houseflies; Hydroxylation; Male; Microsomes; Naphthalenes; Phenobarbital; Propoxur; Species Specificity; Spectrophotometry | 1973 |
Acute lethality for mice following administration of cyclophosphamide with barbiturates.
Topics: Aminopyrine; Animals; Cyclophosphamide; Drug Synergism; Hexobarbital; Lethal Dose 50; Liver; Mice; Mice, Inbred BALB C; Microsomes, Liver; Mortality; Pentobarbital; Phenobarbital | 1973 |
A role of the dietary lipid in the ability of phenobarbital to stimulate drug detoxification.
Topics: Aminopyrine; Animals; Biotransformation; Chlorpromazine; Dietary Fats; Fatty Acids; Female; Glucosephosphate Dehydrogenase; Hexobarbital; In Vitro Techniques; Lipids; Liver; Mice; Mice, Inbred ICR; Microsomes, Liver; Phenobarbital; Rats; Sleep; Time Factors; Zoxazolamine | 1973 |
Interaction of mixed-function oxidation with biosynthetic processes. 2. Inhibition of lipogenesis by aminopyrine in perfused rat liver.
Topics: Acetoacetates; Adenine Nucleotides; Aminopyrine; Animals; Carbon Radioisotopes; Depression, Chemical; Glucose; Hydroxybutyrates; In Vitro Techniques; Kinetics; Lipids; Liver; Male; Oxidation-Reduction; Perfusion; Phenobarbital; Pyruvates; Rats; Tritium; Water | 1973 |
[Treatment of asthmatic attacks and asthmatic conditions in general practice].
Topics: Adolescent; Adult; Aged; Aminopyrine; Asthma; Child; Drug Combinations; Ephedrine; Family Practice; Female; Humans; Male; Middle Aged; Papaverine; Phenobarbital; Theophylline | 1973 |
Effect of sex and age on hepatic N-demethylation and hydroxylation reactions in phenobarbital induced rats.
Topics: Acetanilides; Age Factors; Aminopyrine; Aniline Compounds; Animals; Enzyme Induction; Female; Liver; Male; Methyltransferases; Mixed Function Oxygenases; Morphinans; Morphine; Phenobarbital; Rats; Sex Factors | 1973 |
The effect of carbon disulphide used in combination with carbon tetrachloride on the toxicity of the latter drug for sheep.
Topics: Aminopyrine; Animals; Biopsy; Carbon Disulfide; Carbon Radioisotopes; Carbon Tetrachloride; DDT; Diet; Drug Combinations; Fasciola hepatica; Liver; Male; Microsomes, Liver; Phenobarbital; Proadifen; Sheep | 1973 |
[Studies on the metabolism of aminopyrine in animals during development (author's transl)].
Topics: Age Factors; Aminopyrine; Aminopyrine N-Demethylase; Animals; Animals, Newborn; Depression, Chemical; Female; Male; Microsomes, Liver; Phenobarbital; Rabbits; Spectrophotometry; Time Factors | 1973 |
Metabolism of 8-chloro-6-phenyl-4H-s-triazole(4,3-a)(1,4)benzodiazepine (D-40TA), a new central depressant. 3. Metabolism and tolerance studies in rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzazepines; Brain; Carbon Radioisotopes; Chlordiazepoxide; Drug Tolerance; Heart; Intestine, Small; Kidney; Lung; Male; Muscle Relaxants, Central; Myocardium; Nitrazepam; Phenobarbital; Rats; Spinal Cord; Time Factors; Triazoles; Zoxazolamine | 1974 |
Inhibition by piperonyl butoxide of phenobarbital mediated induction of mouse liver microsomal enzyme activity.
Topics: Aminopyrine; Analysis of Variance; Aniline Compounds; Animals; Enzyme Induction; Male; Methyltransferases; Mice; Mice, Inbred ICR; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Piperonyl Butoxide; Time Factors | 1974 |
Propylene glycol as a drug solvent in the study of hepatic microsomal enzyme metabolism in the rat.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Benzoates; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dealkylation; Dose-Response Relationship, Drug; Hexobarbital; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; Nitro Compounds; Pharmaceutical Preparations; Phenobarbital; Propylene Glycols; Rats; Sleep; Solvents; Time Factors | 1974 |
Some in vitro assay conditions that affect detection and quantitation of phenobarbital-induced increases in hepatic microsomal drug-metabolizing enzyme activity.
Topics: Air; Aminopyrine; Aniline Compounds; Animals; Buffers; Enzyme Induction; Glass; Hexobarbital; Histological Techniques; In Vitro Techniques; Male; Medical Laboratory Science; Microsomes, Liver; Oxygen; Phenobarbital; Phosphates; Proteins; Rats; Sleep; Time Factors | 1970 |
[Kinetics of N-demethylation of amidopyrine with the supernatant portion of the centrifugate of new-born and adult rat liver in the presence of barbital, phenobarbital and phenylbutazone].
Topics: Age Factors; Aminopyrine; Animals; Barbiturates; Female; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Phenylbutazone; Rats; Rats, Inbred Strains | 1972 |
Spectral studies of the binding of O,O-diethyl p-nitrophenylphosphorothionate (parathion) to cytochrome P-450.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Binding Sites; Cytochromes; Hexobarbital; Male; Microsomes, Liver; Morphinans; Parathion; Phenobarbital; Protein Binding; Rabbits; Spectrophotometry | 1972 |
Mixed function oxidase and ethanol metabolism in perfused rat liver.
Topics: Aminopyrine; Animals; Carbon Monoxide; Cytochromes; Ethanol; In Vitro Techniques; Male; Microsomes, Liver; Oxidation-Reduction; Oxygen Consumption; Perfusion; Phenobarbital; Pigments, Biological; Rats | 1972 |
A possible role for the mixed function oxidase enzyme system in the requirement for selenium in the rat.
Topics: Aminopyrine; Animals; Body Weight; Castration; Deficiency Diseases; Estradiol; Female; Feminization; Hexobarbital; Male; Microsomes, Liver; Nutritional Requirements; Oxidoreductases; Phenobarbital; Rats; Selenium; Sex Factors; Testosterone | 1972 |
The effect of diet and drugs on hepatic microsomal aminopyrine N-demethylase activity in vitro and susceptibility to carbon tetrachloride in sheep.
Topics: Aminopyrine; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; DDT; Diet; Dietary Proteins; Food Deprivation; Freezing; Liver; Male; Microsomes, Liver; Oxidoreductases; Phenobarbital; Sheep; Sheep Diseases; Water Deprivation | 1972 |
[Dangers and potential uses of enzyme stimulating medication on newborns and infants].
Topics: Aminopyrine; Chloramphenicol; Drug Synergism; Enzyme Induction; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Jaundice, Neonatal; Liver; Phenobarbital; Pregnancy; Stimulation, Chemical | 1972 |
[Changes of drug effects caused by their metabolism in the liver].
Topics: Aminopyrine; Animals; Cytochromes; Dogs; Drug Stability; Endoplasmic Reticulum; Female; Fetus; Hexobarbital; Humans; Liver; Male; Metabolism; Mice; Pentobarbital; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Pregnancy; Rabbits; Rats; Thiopental | 1971 |
Aminopyrine demethylase--multiplicity shown by dieldrin and DDT inhibition.
Topics: Aminopyrine; Animals; DDT; Dealkylation; Dieldrin; Enzyme Induction; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical | 1971 |
Failure of various drugs to induce drug-metabolizing enzymes in extrahepatic tissues of the rat.
Topics: Adrenal Glands; Aminopyrine; Aniline Compounds; Animals; Brain; Chlorpromazine; Coumarins; Enzyme Induction; Female; Hexobarbital; Hydrochlorothiazide; Intestines; Kidney; Liver; Male; Methylcholanthrene; Metyrapone; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors | 1971 |
A possible role of liver microsomal alkaline ribonuclease in the stimulation of oxidative drug metabolism by phenobarbital, chlordane and chlorophenothane (DDT).
Topics: Aminopyrine; Aniline Compounds; Animals; Chlordan; Cytochromes; DDT; Male; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidoreductases; Oxygen Consumption; Phenobarbital; Rats; Rats, Inbred Strains; Ribonucleases | 1971 |
[Determination of the alkaloid haloids using ionoselective membrane electrodes].
Topics: Alkaloids; Aminopyrine; Halogens; Phenobarbital; Potentiometry | 1971 |
Interference of Beryllium with enzyme induction in rat liver.
Topics: Acetanilides; Aminopyrine; Animals; Beryllium; DNA; DNA Replication; Enzyme Induction; Hydrocortisone; Lethal Dose 50; Liver; Liver Regeneration; Male; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Time Factors; Tryptophan; Tryptophan Oxygenase | 1971 |
[Effect of anticonvulsants on the blood coagulation process in amidopyrine convulsions].
Topics: Aminopyrine; Animals; Anticonvulsants; Blood Coagulation; Dogs; Phenobarbital; Seizures | 1971 |
Effects of non-steroid antirheumatic agents on microsomal drug-metabolizing enzymes of rat liver.
Topics: Aminopyrine; Analgesics; Animals; Anti-Inflammatory Agents; Ascorbic Acid; Aspirin; Benzyl Compounds; Enzyme Induction; Flufenamic Acid; Hexobarbital; In Vitro Techniques; Indazoles; Indomethacin; Liver; Male; Mefenamic Acid; Methylamines; Methyltransferases; Microsomes, Liver; Organ Size; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Salicylamides; Salicylates; Sleep; Sodium Salicylate | 1971 |
Role of steroid hormones in hepatic microsomal enzyme induction.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Aminopyrine; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Castration; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Steroids; Testis | 1971 |
[The pain syndrome of the edentulous alveolar crest and its treatment].
Topics: Administration, Topical; Alveolar Process; Aminopyrine; Anti-Inflammatory Agents; Aspirin; Caffeine; Chlorpromazine; Codeine; Humans; Hyaluronoglucosaminidase; Hydrocortisone; Mouth, Edentulous; Pain; Phenobarbital; Procaine; Promethazine | 1969 |
Effect of administration of 3-aminotriazole on the activity of microsomal drug-metabolizing enzyme systems of rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Blood Proteins; Brain; Brain Chemistry; Cytochromes; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Nitrobenzenes; Pentobarbital; Phenobarbital; Pigments, Biological; Rats; Spectrophotometry; Triazoles; Zoxazolamine | 1967 |
Differences in the oxidative metabolism of drugs by liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Female; Hexobarbital; Liver; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Oxidoreductases; Pentobarbital; Phenobarbital; Proadifen; Rats; Sex Factors; Starvation; Thyroxine; Zoxazolamine | 1969 |
Lack of inhibitory action of aflatoxin on the induction of drug-metabolizing activities of liver microsomes by phenobarbital.
Topics: Aflatoxins; Aminopyrine; Anesthesia; Animals; Injections, Intraperitoneal; Male; Microsomes, Liver; Oxidation-Reduction; Pentobarbital; Phenobarbital; Rats | 1969 |
[Analgesic effect of 2-methylaminoethyl 2,3-dihydrobenzofuran (EPS-4032); mode of action in mice].
Topics: 5-Hydroxytryptophan; Aminopyrine; Analgesics; Animals; Benzofurans; Dihydroxyphenylalanine; Drug Antagonism; Drug Synergism; Drug Tolerance; Lethal Dose 50; Levallorphan; Male; Mice; Morphine; Nialamide; Pargyline; Phenobarbital; Proadifen; Reserpine; Tetrabenazine; Time Factors | 1971 |
Nature of the effect of caffeine on the drug-metabolizing enzymes.
Topics: 17-Hydroxycorticosteroids; Acetanilides; Amino Acids; Aminopyrine; Aniline Compounds; Animals; Caffeine; Cytochromes; Dactinomycin; Drug Antagonism; Enzyme Induction; Female; Humans; Male; Methylation; Microsomes, Liver; Oxidoreductases; Phenobarbital; Pregnanes; Pyridones; Rats; Stimulation, Chemical; Time Factors; Zoxazolamine | 1969 |
The effect of nutrition and hormonal status on cytochrome P-450 and its induction.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Amino Acids; Aminopyrine; Animals; Castration; Cytochromes; Enzyme Induction; Female; Gonadal Steroid Hormones; Liver; Male; Nutritional Physiological Phenomena; Phenobarbital; Protein Deficiency; Rats | 1969 |
The effect of cirrhosis of the liver on microsomal detoxications and cytochrome P-450.
Topics: Aminopyrine; Animals; Carbon Tetrachloride Poisoning; Cytochromes; Liver; Liver Cirrhosis, Experimental; Male; Microsomes, Liver; Phenobarbital; Rats; Water | 1969 |
Ability of the placenta to metabolize oxazepam and aminopyrine before and after drug stimulation.
Topics: Aminopyrine; Animals; Female; Glucuronates; In Vitro Techniques; Oxazepam; Phenobarbital; Placenta; Pregnancy; Rabbits | 1969 |
Alteration of normal development of drug metabolism by injection of growth hormone.
Topics: Aging; Aminopyrine; Animals; Growth Hormone; Injections; Liver; Morphine; Phenobarbital; Rats | 1970 |
Suppression of hepatic ribonuclease during phenobarbital stimulation of drug metabolism.
Topics: Aminopyrine; Animals; Depression, Chemical; Enzyme Induction; Glucuronidase; Liver; Male; Microsomes, Liver; Perfusion; Phenobarbital; Protein Biosynthesis; Rats; Ribonucleases; Stimulation, Chemical; Sucrose; Time Factors; Transferases | 1970 |
[Dolo-Eupaco as an analgesic in gynecology].
Topics: Adult; Aminopyrine; Analgesics; Benzilates; Codeine; Esters; Female; Genital Diseases, Female; Genital Neoplasms, Female; Humans; Middle Aged; Pain; Papaverine; Parasympatholytics; Phenobarbital; Tropanes | 1970 |
[Influence of ascorbic acid on the induction of monooxygenase in liver microsomes].
Topics: Aminopyrine; Animals; Ascorbic Acid; Biotransformation; Cytochromes; Enzyme Induction; Female; Guinea Pigs; Male; Methylcholanthrene; Microsomes, Liver; Oxygenases; Phenobarbital; Scurvy; Stimulation, Chemical | 1970 |
Nickel carbonyl inhibition of induction of aminopyrine demethylase activity in liver and lung.
Topics: Aminopyrine; Animals; Carbon Monoxide; Cell Membrane; Cell Nucleus; Endoplasmic Reticulum; Enzyme Induction; Liver; Lung; Male; Microsomes, Liver; Nickel; Oxidoreductases; Phenobarbital; Phenothiazines; Rats; RNA Nucleotidyltransferases; RNA, Messenger; Time Factors; Tryptophan Oxygenase | 1970 |
Absorption of drugs in vitro from the rat intestine damaged by triparanol or irradiation.
Topics: Aminopyrine; Analgesics; Animals; Aspirin; Depression, Chemical; Ethionamide; Female; Intestinal Absorption; Intestine, Small; Mecamylamine; Morphine; Phenobarbital; Radiation Effects; Radiation Injuries, Experimental; Rats; Scopolamine; Stimulation, Chemical; Triparanol | 1970 |
Substrate-induced spectral change of liver microsomes in phenobarbital and methylcholanthrene-treated male and female rats.
Topics: Aminopyrine; Aniline Compounds; Animals; Chemical Phenomena; Chemistry; Female; Hexobarbital; Male; Meperidine; Methylcholanthrene; Microsomes, Liver; Organ Size; Oxidation-Reduction; Phenobarbital; Proteins; Rats; Spectrophotometry; Spectrum Analysis; Zoxazolamine | 1970 |
Long-term variation in basal and phenobarbital-stimulated oxidative drug metabolism in the rat.
Topics: Aminopyrine; Animals; Basal Metabolism; Hexobarbital; In Vitro Techniques; Liver; Male; Nitrophenols; Oxidation-Reduction; Pharmaceutical Preparations; Phenobarbital; Rats; Sleep; Time Factors | 1970 |
Aminopyrine demethylase. Kinetic evidence for multiple microsomal activities.
Topics: Aminopyrine; Animals; Carbon Monoxide; Chromatography, Thin Layer; Cytochromes; Dealkylation; Enzyme Induction; Ethionine; Goats; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Proadifen; Rats; Spectrophotometry; Stimulation, Chemical; Sulfites | 1970 |
Metabolism of drugs during rat liver regeneration.
Topics: Aminopyrine; Aniline Compounds; Animals; Dealkylation; DNA; Glucuronates; Hepatectomy; Hexosyltransferases; Hydroxylation; Laparotomy; Liver; Liver Regeneration; Male; Methylation; Microsomes, Liver; Mitosis; Mixed Function Oxygenases; Nitrophenols; Nucleoside Diphosphate Sugars; Organ Size; Oxidoreductases; Phenobarbital; Rats; Stimulation, Chemical; Time Factors; Uracil Nucleotides | 1970 |
Comparison of microsomal drug hydroxylation in lung and liver of various species.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Chlorpromazine; Cytochromes; Dealkylation; Enzyme Induction; Female; Guinea Pigs; Hydroxylation; Liver; Lung; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains | 1970 |
Investigations on modern methods of detection of drug allergy.
Topics: Aminopyrine; Basophils; Drug Hypersensitivity; Humans; In Vitro Techniques; Lymphocyte Activation; Lymphocytes; Methods; Penicillins; Phenobarbital; Skin Tests; Sodium Salicylate; Streptomycin; Sulfathiazoles | 1971 |
Additive effects of phenobarbital and high protein diet on liver growth in immature male rats.
Topics: Aminopyrine; Animals; Dietary Proteins; Drug Synergism; Enzyme Induction; Liver; Male; Mitosis; Organ Size; Ornithine Carbamoyltransferase; Oxidoreductases; Phenobarbital; Proteins; Rats | 1971 |
[Age dependent enzyme induction by drugs].
Topics: Age Factors; Aminopyrine; Animals; Animals, Newborn; Biotransformation; Cytochromes; Embryo, Mammalian; Enzyme Induction; Female; Liver; Male; Microsomes; Oxidation-Reduction; Phenobarbital; Pregnancy; Rats; Stimulation, Chemical | 1971 |
Effect of phenobarbital and 3-methylcholanthrene pretreatment on guinea pig hepatic microsomal bilirubin glucuronyltransferase activity.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzphetamine; Bilirubin; Cats; Colorimetry; Enzyme Activation; Glucuronates; Guinea Pigs; Kinetics; Male; Mathematics; Methylcholanthrene; Mice; Microsomes, Liver; Nucleoside Diphosphate Sugars; Phenobarbital; Rabbits; Rats; Species Specificity; Statistics as Topic; Time Factors; Transferases; Uracil Nucleotides | 1971 |
In vitro metabolism of mebutamate.
Topics: Aminopyrine; Animals; Carbamates; In Vitro Techniques; Liver; Male; Microsomes; Phenobarbital; Rabbits; Rats | 1968 |
Effects of various chemical agents on drug metabolism and cholesterol biosynthesis.
Topics: Acetanilides; Acetates; Aminopyrine; Animals; Anticholesteremic Agents; Benzopyrenes; Carbon Isotopes; Chloramphenicol; Cholesterol; Depression, Chemical; Drug Synergism; Ethers; Ethylamines; Hexobarbital; Insecticides; Iproniazid; Liver; Male; Mevalonic Acid; Microsomes; Nitrophenols; Phenobarbital; Proadifen; Rabbits; Rats; Sleep; Time Factors | 1968 |
Tolerance to morphine in the white mice.
Topics: Aminopyrine; Animals; Behavior, Animal; Body Temperature; Body Weight; Drug Tolerance; Mice; Morphine; Phenobarbital; Proadifen; Sodium Salicylate | 1968 |
Hepatic drug metabolism after phenobarbital or 3-methylcholanthrene pretreatment of rats bearing a pituitary tumor.
Topics: Aminopyrine; Animals; Benzopyrenes; Hexobarbital; Liver; Male; Methylcholanthrene; Phenobarbital; Pituitary Neoplasms; Rats; Zoxazolamine | 1968 |
[Separation of vegantine from pyramidon, dial and luminal in vegantalgin and vegantophen by means of thin-layer chromatography].
Topics: Aminopyrine; Barbiturates; Chromatography, Thin Layer; Methods; Phenobarbital | 1968 |
Liver growth associated with the induction of aminopyrine demethylase activity after phenobarbital treatment in adult male rats.
Topics: Aminopyrine; Animals; Body Weight; Injections, Intraperitoneal; Liver; Male; Mitosis; Organ Size; Phenobarbital; Rats | 1968 |
Analgesic profile of tranquillizers in multiple screening tests in mice.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Chlorpromazine; Codeine; Diazepam; Diphenhydramine; Electric Stimulation; Haloperidol; Hot Temperature; Hydroxyzine; Imipramine; Isocarboxazid; Male; Meprobamate; Mice; Morphine; Perphenazine; Phenobarbital; Phenothiazines; Promazine; Promethazine; Reserpine; Tetrabenazine; Thiopental; Time Factors; Tranquilizing Agents | 1968 |
Effect of phenobarbital on the conversion of cholesterol to taurocholic acid. Bile acids and steroids 204.
Topics: 17-Hydroxycorticosteroids; Aminopyrine; Androstanes; Animals; Bile Acids and Salts; Carbon Isotopes; Cholesterol; Chromatography, Paper; Chromatography, Thin Layer; Liver; Male; Phenobarbital; Rats; Sterols; Tritium | 1968 |
[Effects of luminal and oxazepam on drug-metabolizing processes of the rabbit placenta in various periods of pregnancy].
Topics: Aminopyrine; Animals; Female; Oxazepam; Phenobarbital; Placenta; Pregnancy; Pregnancy, Animal; Rabbits | 1968 |
Mephenoxalone hydroxylation in rat liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Catechols; Chlorzoxazone; Liver; Microsomes; Oxazoles; Phenobarbital; Rats; Tranquilizing Agents | 1968 |
The stimulatory effect of phenobarbital on the N-demethylation of P-chloro-N-methylaniline.
Topics: Aminopyrine; Aniline Compounds; Animals; Enzyme Induction; Female; Formaldehyde; Liver; Male; Methods; Methylation; Microsomes; Phenobarbital; Rats | 1969 |
Possible participation of cytochrome P-450 in cholesterol synthesis.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Dioxide; Carbon Isotopes; Cholesterol; Cytochromes; Depression, Chemical; Liver; Male; Methylcholanthrene; Microsomes; Oxygen; Phenobarbital; Rats; Stimulation, Chemical | 1969 |
Gastric dialysis as a possible antidotal procedure for removal of absorbed drugs.
Topics: Aminopyrine; Aniline Compounds; Animals; Aspirin; Chlordiazepoxide; Gastric Lavage; Levorphanol; Mecamylamine; Phenobarbital; Poisoning; Quinine; Rats; Renal Dialysis; Salicylates; Sulfadiazine; Sulfanilamides | 1969 |
Demethylation studies. VI. The inhibition of hepatic microsomal oxygenation by 2,4-dichloro(6-phenylphenoxy)ethylamine and related compounds.
Topics: Aminopyrine; Amitriptyline; Animals; Butylamines; Carbamates; Carbon Isotopes; Dextropropoxyphene; Dogs; Ethylamines; Hexobarbital; Imipramine; In Vitro Techniques; Liver; Male; Mice; Microsomes; Morphinans; Naphthalenes; Nitriles; Phenethylamines; Phenobarbital; Propylamines; Rats | 1969 |
[Studies on the effect of ascorbic acid on the activity and biosynthesis of mixed function oxygenases, as well as the concentration of hemoproteins in the microsome fraction of guinea pig liver].
Topics: Acetanilides; Aminopyrine; Animals; Ascorbic Acid; Cytochromes; Ethionine; Guinea Pigs; Liver; Methylcholanthrene; Microsomes; Oxygenases; Phenobarbital; Scurvy; Stimulation, Chemical | 1969 |
Hormonal regulation of aminopyrine N-demethylase system in rat liver.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Aminopyrine; Androgens; Animals; Castration; Cytochromes; Enzymes; Hydrocortisone; Liver; Male; Microsomes; Oxidoreductases; Phenobarbital; Rats; Testis; Testosterone; Time Factors | 1969 |
Inhibition of hepatic microsomal enzymes by alkylating agents.
Topics: Aging; Aminopyrine; Animals; Cyclophosphamide; Drug Synergism; Enzyme Induction; Enzymes; Liver; Male; Mechlorethamine; Microsomes; Nitrophenols; Organophosphonates; Oxidoreductases; Phenobarbital; Pipobroman; Rats; Time Factors | 1969 |
Studies on drug-metabolizing activity in rats pretreated with phenobarbitone and compounds related to emetine.
Topics: Aminopyrine; Animals; Emetine; Liver; Microsomes; Phenobarbital; Rats; Sulfonamides | 1969 |
Drug-induced porphytin biosynthesis. I. The effect of porphyria-inducing drugs on N-demethylase activity of chick embryo liver.
Topics: Amides; Aminopyrine; Animals; Chemical Phenomena; Chemistry; Chick Embryo; Formaldehyde; In Vitro Techniques; Liver; Microsomes; Oxidoreductases; Phenobarbital; Porphyrias; Porphyrins; Pyridines | 1969 |
Time course differences in the metabolism of drugs by hepatic microsomes from rats, rabbits and mice.
Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Codeine; Hexobarbital; In Vitro Techniques; Liver; Mice; Microsomes; Phenobarbital; Rabbits; Rats; Species Specificity; Sulfonamides; Time; Zoxazolamine | 1966 |
The effect of actinomycin D on post-phenobarbital activity of hepatic microsomal drug-metabolizing enzymes in the rat.
Topics: Aminopyrine; Animals; Dactinomycin; Hexobarbital; In Vitro Techniques; Liver; Microsomes; Phenobarbital; Rats | 1966 |
[Fatal Lyell syndrome caused by Meristin].
Topics: Adolescent; Aminopyrine; Female; Humans; Phenobarbital; Stevens-Johnson Syndrome | 1966 |
[A method for reasonably routine estimation of drugs, especially barbiturates, in narcotic poisoning].
Topics: Aged; Aminopyrine; Barbiturates; Chemistry, Clinical; Chromatography, Thin Layer; Forensic Medicine; Humans; Hypnotics and Sedatives; Male; Methods; Phenacetin; Phenobarbital; Secobarbital; Spectrophotometry; Sulfonamides; Thiopental; Ultraviolet Rays | 1966 |
Effect of pretreatment of rabbits with phenobarbital or 3-methylcholanthrene on the distribution of drug-metabolizing enzyme activity in subfractions of hepatic microsomes.
Topics: Aminopyrine; Amphetamine; Animals; Benzopyrenes; Codeine; Hexobarbital; Liver; Male; Methylcholanthrene; Microscopy, Electron; Microsomes; Mixed Function Oxygenases; Phenobarbital; Pigments, Biological; Rabbits; Zoxazolamine | 1967 |
Influence of phenobarbitone pretreatment on disposition of amidopyrine and its metabolites in rat.
Topics: Aminopyrine; Animals; Bile; Biotransformation; Breath Tests; Drug Interactions; Kinetics; Male; Phenobarbital; Rats | 1980 |
[Methodological approaches to the study of the state of the monooxygenase hydroxylating system of the liver].
Topics: Aminopyrine; Animals; Enzyme Activation; Female; Hexachlorocyclohexane; Hydrolysis; Liver; Male; Methods; Oxygenases; Phenobarbital; Rats; Time Factors | 1983 |
Comparison of hepatic drug-metabolizing enzymes induced by 3-methylcholanthrene and phenobarbital between pre- and postnatal rats.
Topics: Aminopyrine; Animals; Animals, Newborn; Benzo(a)pyrene; Benzopyrenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Fetus; Gestational Age; Hexobarbital; Maternal-Fetal Exchange; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Pregnancy; Rats; Rats, Inbred Strains | 1984 |
[Isolation and characterization of the basic forms of cytochrome P-450 from liver microsomes of C57BL mice after phenobarbital and 3-methylcholanthrene induction].
Topics: Aminopyrine; Animals; Benzo(a)pyrene; Benzopyrenes; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Molecular Weight; Phenobarbital; Substrate Specificity | 1984 |
Use of 13C nuclear magnetic resonance spectroscopy for the evaluation of hepatic drug-metabolizing enzyme activity in perfused mouse livers.
Topics: Aminopyrine; Animals; Enzyme Activation; Inactivation, Metabolic; Liver; Magnetic Resonance Spectroscopy; Malaria; Male; Mice; Phenobarbital; Plasmodium berghei | 1984 |
Enzyme induction in neonates after fetal exposure to antiepileptic drugs.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Anticonvulsants; Breath Tests; Carbamazepine; Carbon Radioisotopes; Enzyme Induction; Female; Humans; Infant, Newborn; Liver; Male; Maternal-Fetal Exchange; Phenobarbital; Phenytoin; Pregnancy; Primidone; Valproic Acid | 1983 |
[Gas chromatography determination of atropine, theophylline, phenobarbital and aminophenazone in tablets].
Topics: Aminopyrine; Atropine; Chromatography, Gas; Phenobarbital; Tablets; Theophylline | 1984 |
The influence of liver disease on the methylation of arsenite in humans.
Topics: Adult; Aminopyrine; Arsenic; Arsenicals; Arsenites; Female; Humans; Liver Diseases; Liver Function Tests; Male; Methylation; Middle Aged; Phenobarbital | 1984 |
[Possibility of N-dimethylnitrosamine formation after parenteral administration of amidopyrine and nitrite to rats].
Topics: Aminopyrine; Animals; Ascorbic Acid; Dimethylnitrosamine; Injections, Intraperitoneal; Injections, Intravenous; Liver; Male; Necrosis; Nitrites; Phenobarbital; Rats | 1984 |
Time course of phenobarbital and cimetidine mediated changes in hepatic drug metabolism.
Topics: Adult; Aminopyrine; Antipyrine; Biotransformation; Breath Tests; Cimetidine; Female; Half-Life; Humans; Liver; Male; Phenobarbital | 1983 |
[Study of the protective effects of phenobarbital and aminopyrine in a toxicologic experiment].
Topics: 1-Propanol; Aminopyrine; Animals; Biotransformation; Liver; Male; Phenobarbital; Rats; Sulfur Dioxide; Toluene | 1983 |
[Effect of pyrazolone derivatives on the level of reduced glutathione in rat liver].
Topics: Aminopyrine; Animals; Antipyrine; Cobalt; Female; Glutathione; Liver; Male; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1983 |
Influence of phenobarbital and 3-methylcholanthrene on the metabolism of aminopyrine in isolated hepatocyte system.
Topics: Aminopyrine; Animals; Chromatography, High Pressure Liquid; Dipyrone; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Liver; Male; Methylcholanthrene; Phenobarbital; Pyrazolones; Rats; Rats, Inbred Strains | 1983 |
Study on in vivo and in vitro metabolism of dimethylformamide in male and female rats.
Topics: Aminopyrine; Animals; Biotransformation; Cobalt; Dimethylformamide; Drug Interactions; Female; Formamides; Injections, Intraperitoneal; Liver; Male; Microsomes; Phenobarbital; Rats; Rats, Inbred Strains; Sex Factors | 1984 |
Enhancement effects of barbital on the teratogenicity of aminopyrine.
Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Barbital; Barbiturates; Cleft Palate; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Female; Fetal Death; Hernia, Umbilical; Humans; Mice; Mice, Inbred ICR; Phenobarbital; Pregnancy; Teratogens | 1984 |
Hybrid information provided by the 14C-aminopyrine breath test. Studies with 14C-monomethylaminoantipyrine in the guinea pig.
Topics: Aminopyrine; Animals; Breath Tests; Carbon Dioxide; Dipyrone; Guinea Pigs; Half-Life; Male; Phenobarbital; Pyrazolones | 1980 |
L-methionine ordinarily does not interfere with the aminopyrine breath test: studies in dogs and rats.
Topics: Aminopyrine; Animals; Breath Tests; Carbon Dioxide; Carbon Radioisotopes; Dogs; Female; Liver; Male; Methionine; Phenobarbital; Rats | 1981 |
[Stability of aminophenazone and phenobarbital in anal suppositories prepared with cocoa oil].
Topics: Aminopyrine; Cacao; Drug Stability; Humans; Oils; Pharmaceutic Aids; Phenobarbital; Rectum; Suppositories | 1982 |
A non-invasive method for the study of hepatic drug metabolism in rodents: antineoplastic drug effects on antipyrine metabolism in mice.
Topics: Aminopyrine; Animals; Antineoplastic Agents; Antipyrine; Carmustine; Half-Life; Liver; Male; Mice; Pharmaceutical Preparations; Phenobarbital; Rats; Rats, Inbred Strains; Saliva | 1982 |
[Enhancement effects of barbital and phenobarbital on aminopyrine-initiated teratogenesis in mice].
Topics: Abnormalities, Drug-Induced; Aminopyrine; Animals; Barbital; Barbiturates; Drug Synergism; Female; Fetus; Mice; Mice, Inbred ICR; Phenobarbital; Pregnancy | 1981 |
[Characterization of storage-induced release reductions in suppositories (author's transl)].
Topics: Aminopyrine; Codeine; Drug Storage; Phenobarbital; Suppositories; Temperature; Trapidil | 1981 |
Oxidation-reduction states of pyridine nucleotide and cytochrome P-450 during mixed-function oxidation in perfused rat liver.
Topics: Aminopyrine; Animals; Cytochrome P-450 Enzyme System; Hexobarbital; Kinetics; Liver; Male; Mixed Function Oxygenases; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Perfusion; Phenobarbital; Rats; Rats, Inbred Strains | 1981 |
Placental transfer and pharmacokinetics of primidone and its metabolites phenobarbital, PEMA and hydroxyphenobarbital in neonates and infants of epileptic mothers.
Topics: Adult; Aminopyrine; Cytochrome P-450 Enzyme System; Epilepsy; Female; Half-Life; Humans; Hydroxylation; Infant; Infant, Newborn; Kinetics; Liver; Male; Malonates; Maternal-Fetal Exchange; Phenobarbital; Phenylethylmalonamide; Pregnancy; Pregnancy Complications; Primidone | 1980 |
[Modification of the caffeine metabolism in mouse liver slices by previous treatment of the experimental animals with ethanol, aminophenazone and phenobarbital].
Topics: Aminopyrine; Animals; Caffeine; Dose-Response Relationship, Drug; Ethanol; In Vitro Techniques; Liver; Male; Mice; Phenobarbital; Rats; Species Specificity | 1980 |
[Case history--red urine].
Topics: Adult; Aminopyrine; Drug Combinations; Female; Humans; Phenobarbital; Porphyria, Acute Intermittent | 1995 |
Effects of ascorbic acid on iproniazid-induced hepatitis in phenobarbital-treated rats.
Topics: Alanine Transaminase; Aminopyrine; Animals; Ascorbic Acid; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Hydrazines; Iproniazid; Kinetics; Liver; Liver Function Tests; Male; Phenobarbital; Rats; Rats, Wistar | 1994 |
Relationship between oxidative hepatic metabolism, urinary sodium excretion and sympathetic nerve activity in experimental cirrhosis in the rat.
Topics: Aminopyrine; Animals; Blood Pressure; Breath Tests; Carbon Tetrachloride; Glomerular Filtration Rate; Liver; Liver Cirrhosis, Experimental; Male; Natriuresis; Norepinephrine; Oxidation-Reduction; Phenobarbital; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Water-Electrolyte Balance | 1995 |
Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity.
Topics: Aminopyrine; Animals; Chloramphenicol; Cyclosporine; Cytochrome P-450 Enzyme System; Enzyme Induction; Free Radical Scavengers; Ketoconazole; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley | 1994 |
Mechanism of carbon tetrachloride autoprotection: an in vivo study based on 13C-aminopyrine and 13C-galactose breath tests.
Topics: Alanine Transaminase; Aminopyrine; Animals; Aspartate Aminotransferases; Carbon Isotopes; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochrome P-450 Enzyme Inhibitors; Galactose; Liver; Liver Function Tests; Male; Phenobarbital; Rats; Rats, Sprague-Dawley; Respiration; Time Factors | 1994 |
Involvement of CYP2E in 8-hydroxylation of theophylline in mouse hepatic microsomes-difference from its N-demethylations.
Topics: Acetone; Aminoacetonitrile; Aminopyrine; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Fomepizole; Hydroxylation; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Nitrophenols; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Pyrazoles; Theophylline | 1996 |
Propofol-induced cytochrome P450 inhibition: an in vitro and in vivo study in rats.
Topics: Aminopyrine; Anesthetics, Intravenous; Animals; Carbon Dioxide; Carbon Isotopes; Cell Survival; Cytochrome P-450 Enzyme Inhibitors; Hepatocytes; In Vitro Techniques; Infusions, Intravenous; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Propofol; Rats; Rats, Sprague-Dawley | 2001 |
Study of possible complex formation between macromolecules and certain pharmaceuticals. II. Polyvinylpyrrolidone with p-aminobenzoic acid, aminopyrine, benzoic acid, salicylic acid, p-hydroxybenzoic acid, m-hydroxybenzoic acid, citric acid, and phenobarbi
Topics: 4-Aminobenzoic Acid; Aminopyrine; Benzoates; Benzoic Acid; Citric Acid; Hydroxybenzoates; Macromolecular Substances; Phenobarbital; Povidone; Salicylates; Salicylic Acid | 1954 |
[Epilepsy therapy with the combination preparation centronal compositum].
Topics: Aminopyrine; Caffeine; Epilepsy; Humans; Hydantoins; Phenobarbital; Porphyrins | 1957 |
[The treatment of painful conditions in the true pelvis of the female with ichthobellol compositum].
Topics: Aminopyrine; Belladonna Alkaloids; Disease; Female; Humans; Lesser Pelvis; Pain; Papaverine; Pelvis; Phenobarbital; Quaternary Ammonium Compounds | 1957 |
[Combined aminophenazone therapy].
Topics: Aminopyrine; Blood Vessels; Electroconvulsive Therapy; Humans; Muscles; Phenobarbital; Psychotherapy; Psychotic Disorders | 1957 |
Inhibition of pentobarbital and meprobamate metabolism by some 'inducers' of drug-metabolizing enzymes.
Topics: Aminopyrine; Chlorobium; Chlorpromazine; Cyclizine; Glutethimide; Meprobamate; Muscle Relaxants, Central; Nikethamide; Pentobarbital; Phenobarbital; Phenylbutazone; Tranquilizing Agents; Zoxazolamine | 1962 |
[THE ELIMINATION OF GLUTETHIMIDE AND OF LONG-ACTING BARBITURATES AFTER TOXICALLY AND THERAPEUTICALLY EFFECTIVE DOSES].
Topics: Aminopyrine; Dogs; Glutethimide; Phenobarbital; Rats; Research; Toxicology; Urine | 1963 |
[THE CUFF METHOD FOR THE ANTALGIC EVALUATION OF DIFFERENT DRUGS].
Topics: Aminopyrine; Arthritis; Arthritis, Rheumatoid; Aspirin; Caffeine; Gout; Osteoarthritis; Phenobarbital; Phenylbutazone; Prednisolone; Procaine; Sciatica; Tendinopathy | 1963 |
[CONTRIBUTION TO THE CLINICAL MANIFESTATIONS OF DRUG ALLERGY].
Topics: Aminopyrine; Aspirin; Atropa belladonna; Drug Hypersensitivity; Liver Extracts; Parasympatholytics; Phenobarbital; Toxicology | 1963 |
THE METABOLISM OF DRUGS BY LIVER MICROSOMES FROM ALLOXAN-DIABETIC RATS: LONG TERM DIABETES.
Topics: Alloxan; Aminopyrine; Aniline Compounds; Animals; Codeine; Diabetes Mellitus, Experimental; Hexobarbital; Insulin; Liver; Liver Glycogen; Metabolism; Microsomes, Liver; Pharmacology; Phenobarbital; Rats; Research | 1963 |
AN ATTEMPT TO DEMONSTRATE CEILING EFFICACY OF ANALGESICS IN RATS.
Topics: Aminopyrine; Amphetamine; Amphetamines; Analgesics; Aspirin; Barbiturates; Chlordiazepoxide; Chlorpromazine; Codeine; Dextropropoxyphene; Diphenhydramine; Meperidine; Meprobamate; Methadone; Morphine; Pharmacology; Phenobarbital; Rats; Rectum; Research; Toxicology | 1964 |
[USE OF THIN LAYER CHROMATOGRAPHY IN THE ANALYSIS OF DISPENSED SUPPOSITORIES].
Topics: Aminopyrine; Chemistry, Pharmaceutical; Chromatography; Chromatography, Thin Layer; Pharmacy; Phenobarbital; Quinine; Research; Suppositories | 1963 |
THE INFLUENCE OF PHENOBARBITAL ADMINISTRATION UPON THE "SOLUBLE" NADP-REQUIRING ENZYMES IN LIVER.
Topics: Aminopyrine; Benzopyrenes; Citrates; Diphenhydramine; Ethionine; Fluorouracil; Gluconates; Hexosephosphates; Isocitrate Dehydrogenase; Liver; Mercaptopurine; Methylcholanthrene; NADP; Oxidoreductases; Pharmacology; Phenobarbital; Phenylalanine; Rats; Research; Uracil | 1964 |
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS.
Topics: Aminopyrine; Androgens; Benzopyrenes; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Ethionine; Liver; Liver Neoplasms; Methionine; Methylcholanthrene; Microsomes; Microsomes, Liver; Orphenadrine; Pharmacology; Phenobarbital; Phenylbutazone; Polycyclic Compounds; Rats; Research; Zoxazolamine | 1963 |
FACTORS AFFECTING HEPATIC MICROSOMAL ENZYME SYSTEMS INVOLVED IN DRUG METABOLISM.
Topics: Alloxan; Aminopyrine; Carcinoma, Hepatocellular; Chlordan; Chlorpromazine; Codeine; Hexobarbital; Jaundice; Jaundice, Obstructive; Liver; Liver Glycogen; Liver Neoplasms; Liver Regeneration; Microsomes; Phenobarbital; Portal System; Research; Starvation | 1963 |
[THE PYROGENIC PRINCIPLE IN THE ROOT OF BRYONIAE ALBAE L].
Topics: Aminopyrine; Blood Cell Count; Bryonia; Chlorpromazine; Guinea Pigs; Mice; Pharmacology; Phenobarbital; Plants, Medicinal; Polysaccharides; Pyrogens; Rabbits; Rats; Research; Species Specificity; Toxicology; Urethane | 1963 |
[THE REPRODUCTION OF AUDIOGENIC CONVULSIONS AFTER THE PRELIMINARY ADMINISTRATION OF PYRAMIDONE TO ANIMALS].
Topics: Acetazolamide; Aminopyrine; Anticonvulsants; Antipyrine; Epilepsy, Reflex; Mice; Pharmacology; Phenobarbital; Phenytoin; Primidone; Rats; Research; Seizures; Sound; Toxicology | 1964 |
[ACCELERATED DRUG DEGRADATION BY ENZYME INDUCTION IN DOGS AFTER TREATMENT WITH PHENOBARBITAL].
Topics: Aminopyrine; Dogs; Enzyme Induction; Hexobarbital; Liver; Metabolism; Microsomes; Phenobarbital; Research; Toxicology | 1964 |
DIFFERENCES IN HEPATIC DRUG METABOLISM IN VARIOUS RABBIT STRAINS BEFORE AND AFTER PRETREATMENT WITH PHENOBARBITAL.
Topics: Aminopyrine; Amphetamine; Amphetamines; Aniline Compounds; Animals; Benzoates; Benzopyrenes; Chlorpromazine; Codeine; Hexobarbital; Liver; Metabolism; Phenobarbital; Rabbits; Research; Species Specificity; Transferases; Zoxazolamine | 1965 |
THE STIMULATION OF DRUG METABOLISM IN VARIOUS RAT HEPATOMAS.
Topics: Aminopyrine; Aniline Compounds; Benzoates; Blood; Carcinoma, Hepatocellular; Chlordan; Hexobarbital; Liver; Liver Neoplasms; Metabolism; Neoplasms; Neoplasms, Experimental; p-Dimethylaminoazobenzene; Pathology; Pharmacology; Phenobarbital; Rats; Research; Sulfanilamide; Sulfanilamides; Sulfonamides; Toxicology | 1965 |
Biochemical background of toxic interaction between tiamulin and monensin.
Topics: Administration, Oral; Aminopyrine; Animals; Anti-Bacterial Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP3A; Dexamethasone; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Ethylmorphine; Female; Ionophores; Male; Microsomes, Liver; Monensin; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Troleandomycin | 2004 |
The effect of temperature on monoxygenase reactions in the microsomal membrane.
Topics: Aminopyrine; Animals; Anisoles; Benzphetamine; Catalysis; Cell Membrane; Ethylmorphine; Ethylmorphine-N-Demethylase; Glycerol; Kinetics; Male; Methylation; Microsomes; NADP; NADPH-Ferrihemoprotein Reductase; Oxidoreductases, N-Demethylating; Phenobarbital; Rats; Rats, Long-Evans; Substrate Specificity; Temperature; Time Factors | 1977 |
Effects of mammalian CYP3A inducers on CYP3A-related enzyme activities in grass carp (Ctenopharyngodon idellus): Possible implications for the establishment of a fish CYP3A induction model.
Topics: Aminopyrine; Aminopyrine N-Demethylase; Animals; Aryl Hydrocarbon Hydroxylases; Bass; Carps; Cell Culture Techniques; Cell Line; Cytochrome P-450 CYP3A; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Erythromycin; Fish Proteins; Hepatocytes; Kidney; Kinetics; Liver; Microsomes, Liver; Models, Animal; Phenobarbital; Rifampin; Steroid Hydroxylases; Substrate Specificity; Testosterone | 2008 |
[Solutions of alkaloid salts, amidazophen and phenobarbital sodium in medicinal syrups].
Topics: Alkaloids; Aminopyrine; Barbiturates; Pharmaceutical Solutions; Phenobarbital; Salts; Sodium; Solutions | 1954 |