phenobarbital has been researched along with aminolevulinic acid in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (65.71) | 18.7374 |
| 1990's | 6 (17.14) | 18.2507 |
| 2000's | 4 (11.43) | 29.6817 |
| 2010's | 2 (5.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atsmon, A; Epstein, O; Schoenfeld, N | 1 |
| de Matteis, F; Unseld, A | 1 |
| Percy, VA; Shanley, BC | 2 |
| Bhat, KS; Padmanaban, G; Sardana, MK | 1 |
| Maxwell, JD; Meyer, UA | 1 |
| Burk, RF; Correia, MA | 1 |
| Degkwitz, E; Dubberstein, M; Walsch, S; Winter, J | 1 |
| Degkwitz, E | 1 |
| Atsmon, A; Mamet, R; Mevasser, R; Schoenfeld, N | 1 |
| Koole-Lesuis, H; van den Berg, JW; Visser, O; Voortman, G; Wilson, JH | 1 |
| Berk, PD; Blaschke, TF; Jones, MJ; Kiang, CL; Okuda, H; Sardana, MK; Sassa, S; Shrager, RI; Tavoloni, N; Waggoner, JG | 1 |
| Atsmon, A; Bomstein, Y; Mamet, R; Mevasser, R; Schoenfeld, N | 1 |
| Bonkovsky, HL | 1 |
| Bement, WJ; Elder, GH; Gorman, N; Lambrecht, RW; Roberts, AG; Sinclair, JA; Sinclair, PR; Urquhart, AJ | 1 |
| Omura, T; Sadano, H | 1 |
| Piper, WN; Tephly, TR | 1 |
| Becker, DM; Kramer, S; Viljoen, JD | 1 |
| Goldenberg, GJ | 1 |
| Levin, W; Lu, AY | 1 |
| Edwards, AM; Glistak, ML; Lucas, CM; Wilson, PA | 1 |
| Johnson, JD; Martinez, CW; Ostrander, CR; Wetmore, DL | 1 |
| Bruinvels, J; Pepplinkhuizen, L; Schouten, MJ; Wilson, JH | 1 |
| Althaus, FR; Giger, U; Hirsiger, H; Meier, PJ; Meyer, UA | 1 |
| Fischer, VW; Hjelle, JJ; Poklis, A | 1 |
| Adzharov, D; Chernev, K; Ivanov, E | 1 |
| Fuchs, T; Ippen, H; Seubert, A; Seubert, S | 1 |
| Aguzzi, A; Brandner, S; Bürki, K; Grandchamp, B; Ledermann, B; Lindberg, RL; Meyer, UA; Porcher, C | 1 |
| Buzaleh, AM; del Carmen Batlle, AM; Nuñez, G; Vazquez, ES | 1 |
| Bement, WJ; Dalton, TP; Gorman, N; Nebert, DW; Sinclair, JF; Sinclair, PR; Smith, AG; Walton, HS | 1 |
| Hoffmann, F; Lindberg, RL; Meyer, UA; Schuurmans, MM | 1 |
| Blomberg, P; Harper, P; Johansson, A; Möller, C; Nowak, G | 1 |
| Correia, MA; Han, XM; Hefner, C; Lee, G; Maher, JJ | 1 |
| Berger, S; Chen, B; Desnick, RJ; Edelmann, W; Gama-Sosa, MA; Gan, L; Phillips, JD; Pollak, DD; Yasuda, M; Yu, C; Zhang, J | 1 |
| Fontanellas, A; Jericó, D; Parra-Guillén, ZP; Sampedro, A; Serrano-Mendioroz, I; Trocóniz, IF; Vera-Yunca, D | 1 |
1 review(s) available for phenobarbital and aminolevulinic acid
| Article | Year |
|---|---|
The resolution and reconstitution of the liver microsomal hydroxylation system.
Topics: Aminolevulinic Acid; Animals; Benzopyrenes; Carbon Radioisotopes; Choline; Chromatography, DEAE-Cellulose; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Detergents; Electron Transport; Glycerol; Isotope Labeling; Macromolecular Substances; Male; Methods; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Peptide Hydrolases; Phenobarbital; Phosphatidylcholines; Precipitin Tests; Rats; Solubility; Structure-Activity Relationship; Testosterone; Time Factors; Tritium; Trypsin; Ultracentrifugation | 1974 |
34 other study(ies) available for phenobarbital and aminolevulinic acid
| Article | Year |
|---|---|
The effect of beta-adrenergic blocking agents on experimental porphyria induced by 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) in vivo and in vitro.
Topics: 5-Aminolevulinate Synthetase; Adrenergic beta-Antagonists; Aminolevulinic Acid; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Liver; Male; Phenobarbital; Porphobilinogen; Porphyrias; Porphyrins; Propranolol; Pyridines; Rats | 1976 |
Destruction of endogenous and exogenous haem by 2-allyl-2-isopropylacetamide: role of the liver cytochrome P-450 which is inducible by phenobarbitone.
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Paralysis; Phenobarbital; Rats; Sleep; Zoxazolamine | 1978 |
Lack of effect of phenobarbitone treatment on metabolism and brain uptake of delta-aminolaevulinic acid in rats.
Topics: Aminolevulinic Acid; Animals; Brain; Cytochrome P-450 Enzyme System; Female; Levulinic Acids; Liver; Phenobarbital; Porphobilinogen; Rats | 1977 |
Role of haem in the synthesis and assembly of cytochrome P-450.
Topics: Aminolevulinic Acid; Animals; Apoenzymes; Binding Sites; Cytochrome P-450 Enzyme System; Heme; Hemin; Male; Microsomes, Liver; Phenobarbital; Rats; Triazoles | 1977 |
Effect of lead on hepatic delta-aminolaevulinic acid synthetase activity in the rat: a model for drug sensitivity in intermittent acute porphyria.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; Drug Hypersensitivity; Enzyme Induction; Lead; Liver; Male; Phenobarbital; Porphyrias; Rats | 1976 |
Hepatic heme metabolism in selenium-deficient rats: effect of phenobarbital.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; Heme; Liver; Male; Microsomes; Microsomes, Liver; Oxygenases; Phenobarbital; Rats; Selenium; Spleen | 1976 |
Ascorbic acid and cytochromes.
Topics: Adrenal Glands; Aminolevulinic Acid; Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Collagen; Cycloheximide; Cytochrome P-450 Enzyme System; Cytochromes; Dactinomycin; Guinea Pigs; Iron; Kidney Cortex; Liver; Phenobarbital; Spleen | 1975 |
[Proceedings: Vitamin C and cytochrome].
Topics: Aminolevulinic Acid; Animals; Ascorbic Acid Deficiency; Cytochrome P-450 Enzyme System; Cytochromes; Gluconates; Guinea Pigs; Microsomes, Liver; Phenobarbital | 1975 |
Experimental latent and acute porphyria in the non-fasted rat; preventive effect of propranolol.
Topics: Acute Disease; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Coproporphyrins; Dicarbethoxydihydrocollidine; Feces; Male; Phenobarbital; Porphobilinogen; Porphyrias; Propranolol; Protoporphyrins; Rats; Rats, Inbred Strains | 1991 |
Porphyrin synthesis by human hepatocytes and HepG2 cells--effects of enzyme inducers and delta-aminolevulinic acid.
Topics: Aminolevulinic Acid; Carcinoma, Hepatocellular; Cells, Cultured; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Enzyme Induction; Hexachlorobenzene; Humans; Hydroxymethylbilane Synthase; Liver; Liver Neoplasms; Methylcholanthrene; Phenobarbital; Porphyrins; Tumor Cells, Cultured; Uroporphyrinogen Decarboxylase | 1991 |
Phenobarbital does not increase early labeling of bilirubin from 4-[14C]-delta-aminolevulinic acid in man and rat.
Topics: Aminolevulinic Acid; Animals; Bile; Bilirubin; Carbon Radioisotopes; Glycine; Humans; Liver; Male; Organ Size; Phenobarbital; Rats; Rats, Inbred Strains | 1991 |
L-Alanine: 4,5-dioxovalerate transaminase does not regulate heme synthesis in rat liver.
Topics: Alanine; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Chick Embryo; Dicarbethoxydihydrocollidine; Enzyme Induction; Heme; Hemin; Liver; Male; Phenobarbital; Porphyrins; Rats; Rats, Inbred Strains; Transaminases; Valerates | 1990 |
Mechanism of iron potentiation of hepatic uroporphyria: studies in cultured chick embryo liver cells.
Topics: 5-Aminolevulinate Synthetase; Acetates; Alcohols; Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Chromatography, High Pressure Liquid; Drug Synergism; Ferric Compounds; Glutethimide; Heme Oxygenase (Decyclizing); Isomerism; Liver; Metals; Nitrilotriacetic Acid; Oxidation-Reduction; Phenobarbital; Polycyclic Compounds; Porphyrins; Uroporphyrins | 1989 |
Uroporphyria produced in mice by 20-methylcholanthrene and 5-aminolaevulinic acid.
Topics: Aminolevulinic Acid; Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Hexachlorobenzene; Levulinic Acids; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Oxidoreductases; Phenobarbital; Porphyrias; Porphyrins; Uroporphyrinogen Decarboxylase; Uroporphyrinogens | 1988 |
Incorporation of heme to microsomal cytochrome P-450 in the absence of protein biosynthesis.
Topics: Aminolevulinic Acid; Animals; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Cytosol; Heme; In Vitro Techniques; Leucine; Male; Microsomes, Liver; Phenobarbital; Precipitin Tests; Rats; Rats, Inbred Strains | 1985 |
The reversal of experimental porphyria and the prevention of induction of hepatic mixed-function oxidase by acetate.
Topics: 5-Aminolevulinate Synthetase; Acetates; Aminolevulinic Acid; Animals; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dicarboxylic Acids; Enzyme Induction; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Porphobilinogen; Porphyrias; Porphyrins; Pyridines; Rats; Spectrophotometry; Sulfanilamides | 1974 |
Delta-aminolevulinic acid uptake by rabbit brain cerebral cortex.
Topics: Allosteric Regulation; Amino Acids; Aminolevulinic Acid; Animals; Biological Transport, Active; Calcium; Carbon Radioisotopes; Cerebral Cortex; Cyanides; Dinitrophenols; In Vitro Techniques; Inulin; Ketoglutaric Acids; Kinetics; Levulinic Acids; Male; Osmolar Concentration; Ouabain; Phenobarbital; Porphobilinogen; Potassium; Rabbits; Sodium; Temperature; Time Factors | 1974 |
Drug-induced stimulation of nitrogen mustard and choline transport and other systems in L5178Y lymphoblasts in vitro.
Topics: Amino Acids; Aminoisobutyric Acids; Aminolevulinic Acid; Animals; Atropine; Biological Transport; Cell Line; Cells, Cultured; Choline; Cocaine; Cyclopentanes; Diazepam; Glucose; Leucine; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocytes; Mechlorethamine; Mice; Morphine; Phenobarbital; Stimulation, Chemical | 1974 |
7-Ethoxycoumarin deethylase activity as a convenient measure of liver drug metabolizing enzymes: regulation in cultured rat hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Aminolevulinic Acid; Animals; Bucladesine; Cells, Cultured; Dexamethasone; Enzyme Induction; Glucagon; Heme; Insulin; Liver; Methylcholanthrene; Niacinamide; Oxygenases; Phenobarbital; Pyridines; Rats; Rats, Inbred Strains | 1984 |
Developmental changes in bilirubin production in the rat.
Topics: Age Factors; Aminolevulinic Acid; Animals; Bilirubin; Carbon Dioxide; Carbon Monoxide; Glycine; Heme Oxygenase (Decyclizing); Intestinal Mucosa; Liver; Phenobarbital; Rats; Rats, Inbred Strains; Respiration | 1983 |
Serine and glycine-induced catalepsy in porphyric rats: an animal model for psychosis?
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Catalepsy; Disease Models, Animal; Glycine; Humans; Male; Phenobarbital; Porphobilinogen; Porphyrias; Psychotic Disorders; Rats; Rats, Inbred Strains; Serine | 1983 |
Factors affecting haem degradation in rat brain.
Topics: Allylisopropylacetamide; Aminolevulinic Acid; Animals; Biotransformation; Brain; Female; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Lead; Liver; Phenobarbital; Rats | 1980 |
Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects.
Topics: Aminolevulinic Acid; Animals; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Heme; Hemeproteins; Liver; Male; Microsomes, Liver; Mitochondria; Mixed Function Oxygenases; Phenobarbital; Rats | 1980 |
The effect of inorganic lead on heptic biochemical and ultrastructural changes produced by phenobarbital.
Topics: Aminolevulinic Acid; Animals; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Heme; Lead; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1982 |
[Changes in liver microsomal enzymes and the synthesis of delta-aminolevulinic acid in short-term exposure of rabbits to allylisopropylacetamide, hexachlorobenzene and phenobarbital].
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chlorobenzenes; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexachlorobenzene; Levulinic Acids; Microsomes, Liver; Phenobarbital; Rabbits; Time Factors | 1982 |
Anticonvulsant-induced unclassified porphyria.
Topics: Adult; Aminolevulinic Acid; Anticonvulsants; Diagnosis, Differential; Epilepsy; Humans; Male; Phenobarbital; Phenytoin; Porphobilinogen; Porphyrias; Porphyrins | 1980 |
Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria.
Topics: Aminolevulinic Acid; Animals; Atrophy; Axons; Base Sequence; Chimera; Disease Models, Animal; Female; Gene Targeting; Humans; Hydroxymethylbilane Synthase; Kidney; Liver; Male; Mice; Molecular Sequence Data; Motor Activity; Muscle, Skeletal; Nervous System Diseases; Phenobarbital; Porphyria, Acute Intermittent; RNA, Messenger | 1996 |
Effect of chronic anesthesia on the drug-metabolizing enzyme system and heme pathway regulation.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Anesthetics, Inhalation; Animals; Cytochrome P-450 Enzyme System; Enflurane; Heme; Hypnotics and Sedatives; Isoflurane; Liver; Male; Mice; Phenobarbital; Porphobilinogen; Porphyrins | 1997 |
CYP1A2 is essential in murine uroporphyria caused by hexachlorobenzene and iron.
Topics: Aminolevulinic Acid; Animals; Antibodies; Blotting, Western; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Imidazoles; Iron; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred C57BL; Microsomes, Liver; Oxazines; Oxidation-Reduction; Phenobarbital; Time Factors; Uroporphyrinogens; Uroporphyrins | 2000 |
Zinc mesoporphyrin represses induced hepatic 5-aminolevulinic acid synthase and reduces heme oxygenase activity in a mouse model of acute hepatic porphyria.
Topics: 5-Aminolevulinate Synthetase; Acute Disease; Aminolevulinic Acid; Animals; Arginine; Cytosol; Drug Combinations; Female; Heme; Heme Oxygenase (Decyclizing); Injections, Intraperitoneal; Liver; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Phenobarbital; Porphyria, Acute Intermittent; Porphyrias, Hepatic; Reference Values; RNA, Messenger | 2001 |
Adenoviral-mediated expression of porphobilinogen deaminase in liver restores the metabolic defect in a mouse model of acute intermittent porphyria.
Topics: Adenoviridae; Aminolevulinic Acid; Animals; Disease Models, Animal; Gene Expression; Genetic Therapy; Hydroxymethylbilane Synthase; Liver; Luciferases; Mice; Mice, Mutant Strains; Phenobarbital; Porphyria, Acute Intermittent; Tissue Distribution | 2004 |
Heme-reversible impairment of CYP2B1/2 induction in heme-depleted rat hepatocytes in primary culture: translational control by a hepatic alpha-subunit of the eukaryotic initiation factor kinase?
Topics: Aminolevulinic Acid; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 CYP2B1; eIF-2 Kinase; Enzyme Induction; Heat-Shock Proteins; Heme; Hepatocytes; Molecular Chaperones; Peptide Elongation Factor 2; Phenobarbital; Phosphorylation; Proteins; Protoporphyrins; Pyrimethamine; Rats; Steroid Hydroxylases; Transcriptional Activation | 2005 |
Homozygous hydroxymethylbilane synthase knock-in mice provide pathogenic insights into the severe neurological impairments present in human homozygous dominant acute intermittent porphyria.
Topics: Aminolevulinic Acid; Animals; Central Nervous System; Gene Knock-In Techniques; Genes, Dominant; Homozygote; Humans; Hydroxymethylbilane Synthase; Liver; Mice; Mutation, Missense; Myelin Sheath; Nervous System Diseases; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Psychomotor Disorders | 2019 |
Computational disease model of phenobarbital-induced acute attacks in an acute intermittent porphyria mouse model.
Topics: Aminolevulinic Acid; Animals; Computer Simulation; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Phenobarbital; Porphobilinogen; Porphyria, Acute Intermittent; Porphyrins | 2019 |