phenobarbital and alprazolam

phenobarbital has been researched along with alprazolam in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's7 (43.75)18.2507
2000's6 (37.50)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Abraham, MH; Acree, WE; Ibrahim, A1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
McNichol, RW; Vogtsberger, KN; Zule, WA1
Commissaris, RL; Ellis, DM; Fontana, DJ; McCloskey, TC1
Burke, WM; Dhopesh, V; Maany, I; Ravi, NV; Woody, GE1
Earley, B; Leonard, BE; O'Connor, WT1
Campbell, M; Cueva, JE1
Born, JD; Brichant, JF; Hans, P; Lamy, M; Pieron, F; Pieyns, P1
Charpentier, KP; Greenblatt, DJ; Harmatz, JS; Poku, JW; Shader, RI; von Moltke, LL1
Commissaris, RL; Fontana, DJ; McMiller, LV1
Groenink, L; Maes, RA; Olivier, B; Oosting, RS; Pattij, T; van der Gugten, J1

Reviews

2 review(s) available for phenobarbital and alprazolam

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10

    Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents

1995

Other Studies

14 other study(ies) available for phenobarbital and alprazolam

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Phenobarbital as an adjunct for alprazolam withdrawal.
    The American journal of psychiatry, 1990, Volume: 147, Issue:12

    Topics: Adult; Alprazolam; Back Pain; Female; Headache; Humans; Middle Aged; Phenobarbital; Substance Withdrawal Syndrome

1990
Chronic anxiolytic treatment effects on conflict behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:1

    Topics: Alprazolam; Animals; Behavior, Animal; Chlordiazepoxide; Conflict, Psychological; Dose-Response Relationship, Drug; Female; Flumazenil; Panic; Phenobarbital; Prohibitins; Rats; Rats, Inbred Strains

1990
Detoxification with phenobarbital of alprazolam-dependent polysubstance abusers.
    Journal of substance abuse treatment, 1990, Volume: 7, Issue:1

    Topics: Adult; Alprazolam; Combined Modality Therapy; Follow-Up Studies; Humans; Illicit Drugs; Male; Methadone; Opioid-Related Disorders; Phenobarbital; Substance-Related Disorders

1990
Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolam: studies on the olfactory bulbectomized rat model of depression.
    British journal of clinical pharmacology, 1985, Volume: 19 Suppl 1

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Biogenic Amines; Body Weight; Brain Chemistry; Choice Behavior; Depressive Disorder; Diazepam; Feeding Behavior; Humans; Male; Neurotransmitter Agents; Olfactory Bulb; Phenobarbital; Rats; Rats, Inbred Strains

1985
Elevated plasma alpha 1-acid glycoprotein levels: lack of connection to resistance to vecuronium blockade induced by anticonvulsant therapy.
    Journal of neurosurgical anesthesiology, 1997, Volume: 9, Issue:1

    Topics: Adult; Alprazolam; Anticonvulsants; Atropine; Biomarkers; Carbamazepine; Drug Interactions; Drug Resistance; Humans; Hydroxyzine; Hypnotics and Sedatives; Middle Aged; Neuromuscular Nondepolarizing Agents; Neurosurgery; Orosomucoid; Phenobarbital; Phenytoin; Vecuronium Bromide

1997
Alprazolam hydroxylation by mouse liver microsomes in vitro: the effect of age and phenobarbital induction.
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:2

    Topics: Aging; Alprazolam; Animals; Anti-Anxiety Agents; Biotransformation; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydroxylation; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Phenobarbital

1997
Depletion of brain norepinephrine: differential influence on anxiolyic treatment effects.
    Psychopharmacology, 1999, Volume: 143, Issue:2

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzylamines; Biogenic Monoamines; Brain Chemistry; Conflict, Psychological; Desipramine; Dose-Response Relationship, Drug; Female; Hypnotics and Sedatives; Monoamine Oxidase Inhibitors; Norepinephrine; Phenelzine; Phenobarbital; Rats; Rats, Sprague-Dawley; Sympathomimetics

1999
GABA(A)-benzodiazepine receptor complex sensitivity in 5-HT(1A) receptor knockout mice on a 129/Sv background.
    European journal of pharmacology, 2002, Jun-28, Volume: 447, Issue:1

    Topics: Alprazolam; Animals; Anti-Anxiety Agents; Diazepam; Ethanol; Fever; Flumazenil; GABA Antagonists; Hypnotics and Sedatives; Male; Maze Learning; Mice; Mice, Knockout; Pentylenetetrazole; Phenobarbital; Receptors, GABA-A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex; Species Specificity; Stress, Physiological

2002