phenobarbital has been researched along with aflatoxin b1 in 54 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (50.00) | 18.7374 |
| 1990's | 21 (38.89) | 18.2507 |
| 2000's | 5 (9.26) | 29.6817 |
| 2010's | 1 (1.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, DX | 1 |
| Buhler, DR; McCrary, JA; Novak, RF; Primiano, T; Springer, DL; Zangar, RC | 1 |
| Cha, YN; Choi, CY; Park, EH; Park, SH | 1 |
| Chen, ZY; Eaton, DL | 2 |
| Gerbracht, U; Huber, W; Kraupp-Grasl, B; Putz, B; Schulte-Hermann, R | 1 |
| Lamartiniere, CA | 1 |
| Bauer-Hofmann, R; Buchmann, A; Schwarz, M; Wright, AS | 1 |
| Büsser, MT; Lutz, WK | 1 |
| Bohm, LS; Gopalan, P; Ho, LL; Jhee, EC; Lotlikar, PD; Raj, HG; Tsuji, K | 1 |
| Faletto, MB; Gurtoo, HL | 1 |
| Gelboin, HV; Jeffrey, AM; Li, MH; Lu, SJ; Park, SS | 1 |
| Fukushima, S; Imaida, K; Ito, N; King, CM; Lee, MS; Ohshima, M; Shirai, T | 1 |
| Ali, II; Couri, D; Milks, MM; Wilt, SR | 1 |
| Bloom, SE; Hamilton, JW | 2 |
| Fukuhara, M; Mizokami, K; Nohmi, T; Omori, Y; Takanaka, A | 1 |
| Bellamy, GM; Eaton, DL; Holeski, CJ; Monroe, DH | 1 |
| Bansal, SK; Gurtoo, HL; Love, JH | 1 |
| Kamataki, T; Kato, R; Kawano, S; Maeda, K; Mizoguchi, I; Nakao, T | 1 |
| Hsieh, DP; Marshall, MR; Wei, CI | 1 |
| Campbell, TC; Chen, J; Combs, GF; Goetchius, MP | 1 |
| Byard, JL; Hsieh, DP; Loury, DJ | 1 |
| Fujii-Kuriyama, Y; Mizukami, Y; Muramatsu, M; Taniguchi, T | 1 |
| Campbell, TC; Faris, RA | 1 |
| Yu, FL | 1 |
| Metcalfe, SA; Neal, GE | 1 |
| Dalvi, RR; McGowan, C | 1 |
| Colley, PJ; Metcalfe, SA; Neal, GE | 1 |
| Campbell, TC; Mainigi, KD | 1 |
| Hsieh, DP; Rice, DW; Wei, CI; Wong, ZA | 1 |
| Kamataki, T; Kato, R; Uchimaru, R; Ueno, Y; Yoshizawa, H | 1 |
| Clark, JD; Hatch, RC; Jain, AV; Mahaffey, EA; Weiss, R | 1 |
| Clark, JD; Hatch, RC; Jain, AV; Weiss, R | 1 |
| DiRenzo, AB; Gandolfi, AJ; McDougal, JN; Sipes, IG | 1 |
| Astashkin, EI; Prikhodko, AZ | 1 |
| Antignac, E; Fukuhara, M; Fukusen, N; Kato, K; Kimura, M | 1 |
| Bartsch, H; Kirby, GM; Lang, MA; Pelkonen, P; Wild, CP | 1 |
| Davies, R; Hayes, JD; Judah, DJ; McLellan, LI; Neal, GE | 1 |
| Hayes, JD; Judah, DJ; McLellan, LI; Neal, GE | 1 |
| Grasl-Kraupp, B; Huber, W; Schulte-Hermann, R; Waldhör, T | 1 |
| Coles, B; Gilmore, KS; Guengerich, FP; Harris, J; Harris, TM; Kensler, TW; Ketterer, B; Meyer, DJ; Raney, K | 1 |
| Gopalan, P; Kimura, M; Lehmann, K; Lotlikar, PD; Sato, K; Shinozuka, H; Tsuji, K | 1 |
| Galloway, SM; Johnson, TE; Umbenhauer, DR | 1 |
| Berges, R; Chaumontet, C; Heberden, C; Honikman-Leban, E; Krutovskikh, VA; Le Bon, AM; Martel, P; Shahin, MM; Suschetet, M; Yamasaki, H | 1 |
| Gopalan-Kriczky, P; Hiruma, S; Kimura, M; Lehmann, K; Lotlikar, PD; Qin, GZ; Sato, K; Shinozuka, H | 1 |
| Ha, TG; Jang, JJ; Kim, ND; Kim, SG | 1 |
| Adav, SS; Govindwar, SP | 1 |
| Ball, HW; Manson, MM; McLellan, LI; Shepherd, AG | 1 |
| Canivenc-Lavier, MC; Le Bon, AM; Siess, MH; Suschetet, M | 1 |
| Alvarez, ML; Carnovale, CE; Carrillo, MC; Favre, C; Lugano, MC; Monti, JA; Pisani, GB; Scapini, C | 1 |
| Jiang, Y; Lee, CS; Locascio, LE; Wang, PC | 1 |
| Berenbaum, MR; Niu, G; Schuler, MA; Wen, Z; Zeng, RS | 1 |
| Aubrecht, J; Buick, JK; Fornace, AJ; Hyduke, DR; Li, HH; Moffat, I; Recio, L; Swartz, CD; Williams, A; Yauk, CL | 1 |
54 other study(ies) available for phenobarbital and aflatoxin b1
| Article | Year |
|---|---|
[Effects of harman and norharman on aflatoxin B1 and aminopyrine metabolism by phenobarbital and 3-methylcholanthrene-induced rat liver microsomes].
Topics: Aflatoxin B1; Aminopyrine N-Demethylase; Animals; Carbolines; Harmine; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar | 1992 |
Changes in adult metabolism of aflatoxin B1 in rats neonatally exposed to diethylstilbestrol. Alterations in alpha-class glutathione S-transferases.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Animals; Biotransformation; Blotting, Western; Diethylstilbestrol; DNA; Enzyme Induction; Female; Glutathione Transferase; Liver; Male; Phenobarbital; Pregnancy; Pregnenolone Carbonitrile; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley | 1992 |
Alteration of aflatoxin B1 metabolic profiles and reduction of aflatoxin B1 mutagenicity by hepatic microsomes of rats fed butylated hydroxyanisole.
Topics: Aflatoxin B1; Animals; Butylated Hydroxyanisole; Chromatography, High Pressure Liquid; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Phenobarbital; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1991 |
Differential regulation of cytochrome(s) P450 2B1/2 by phenobarbital in hepatic hyperplastic nodules induced by aflatoxin B1 or diethylnitrosamine plus 2-acetylaminofluorene in male F344 rats.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Alkylation; Animals; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Enzyme Induction; Hepatectomy; Hyperplasia; Liver; Male; Oxazines; Phenobarbital; Rats; Rats, Inbred F344; Stimulation, Chemical | 1991 |
Tumor promotion by the peroxisome proliferator nafenopin involving a specific subtype of altered foci in rat liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; Body Weight; Carcinoma; Female; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Nafenopin; Phenobarbital; Propionates; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Neonatal diethylstilbestrol treatment alters aflatoxin B1-DNA adduct concentrations in adult rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Animals, Newborn; Body Weight; Carcinogens; Chromatography, High Pressure Liquid; Diethylstilbestrol; DNA; Female; Liver; Male; Methylcholanthrene; Organ Size; Phenobarbital; Pyrimidines; Rats; Rats, Inbred Strains; Testis; Time Factors | 1990 |
Mutations in the Ha-ras proto-oncogene in spontaneous and chemically induced liver tumours of the CF1 mouse.
Topics: Aflatoxin B1; Aflatoxins; Animals; Base Sequence; Carcinogens; Dieldrin; DNA, Neoplasm; Genes, ras; Liver Neoplasms; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Phenobarbital; Polymerase Chain Reaction | 1990 |
Stimulation of DNA synthesis in rat and mouse liver by various tumor promoters.
Topics: Adipates; Aflatoxin B1; Aflatoxins; Aldrin; Animals; Benzidines; Biological Availability; Carbon Tetrachloride; Carcinogens; Cell Division; Circadian Rhythm; DDT; Diethylhexyl Phthalate; DNA; DNA Replication; Female; Hexachlorocyclohexane; Isomerism; Liver; Liver Neoplasms; Male; Mice; Phenobarbital; Polychlorinated Dibenzodioxins; Rats; Thioacetamide | 1987 |
A mechanism of inhibition of aflatoxin B1-DNA binding in the liver by phenobarbital pretreatment of rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cytosol; DNA; Glutathione; Glutathione Transferase; Kinetics; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Subcellular Fractions | 1989 |
The effect of inducers of mixed-function oxidases on hepatic microsome-mediated aflatoxin B1 transformation in C3H/10T1/2 cells.
Topics: Aflatoxin B1; Aflatoxins; Animals; Aroclors; Biotransformation; Cell Survival; Chlorodiphenyl (54% Chlorine); DNA; In Vitro Techniques; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains | 1989 |
Metabolism of fusarin C by rat liver microsomes. Role of esterase and cytochrome P-450 enzymes with respect to the mutagenicity of fusarin C in Salmonella typhimurium.
Topics: Aflatoxin B1; Aflatoxins; Animals; Antibodies, Monoclonal; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Esterases; Isoflurophate; Microsomes, Liver; Mutagenicity Tests; Phenobarbital; Polyenes; Rats; Salmonella typhimurium | 1989 |
Different responses to phenobarbital promotion in the development of gamma-glutamyltranspeptidase-positive foci in the liver of rats initiated with diethylnitrosamine, N-hydroxy-2-acetyl-aminofluorene and aflatoxin B1.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; gamma-Glutamyltransferase; Hydroxyacetylaminofluorene; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred F344 | 1985 |
The effects of selenium on the emergence of aflatoxin B1-induced enzyme-altered foci in rat liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Rats; Rats, Inbred Strains; Selenium | 1985 |
Correlation between induction of xenobiotic metabolism and DNA damage from chemical carcinogens in the chick embryo in vivo.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Chick Embryo; DNA; Dose-Response Relationship, Drug; Enzyme Induction; Erythrocytes; Liver; Lung; Methyl Methanesulfonate; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls; Time Factors | 1986 |
Purification and characterization of a form of cytochrome P-450 with high specificity for aflatoxin B1 from 3-methylcholanthrene-treated hamster liver.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cricetinae; Cytochrome P-450 Enzyme System; Isoenzymes; Liver; Male; Mesocricetus; Methylcholanthrene; Molecular Weight; Mutagenicity Tests; Phenobarbital; Salmonella typhimurium | 1986 |
Effects of phenobarbital on the biliary excretion of aflatoxin P1-glucuronide and aflatoxin B1-S-glutathione in the rat.
Topics: Aflatoxin B1; Aflatoxins; Animals; Bile; Biotransformation; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; DNA; Glucuronates; Glutathione; Liver; Male; Mass Spectrometry; Phenobarbital; Rats; Rats, Inbred Strains | 1987 |
Resolution by high-pressure liquid chromatography and partial characterization of multiple forms of cytochrome P-450 from hepatic microsomes of phenobarbital-treated rats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Catalysis; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Cytochrome P-450 Enzyme System; DNA; Electrophoresis, Polyacrylamide Gel; Enzyme Induction; Male; Microsomes, Liver; Oxidation-Reduction; Peptide Fragments; Phenobarbital; Rats; Rats, Inbred Strains; Spectrum Analysis | 1985 |
Activation and inactivation of a variety of mutagenic compounds by the reconstituted system containing highly purified preparations of cytochrome P-450 from rat liver.
Topics: Aflatoxin B1; Aflatoxins; Amino Acids; Animals; Azo Compounds; Benzoflavones; beta-Naphthoflavone; Biotransformation; Carcinogens; Cytochrome P-450 Enzyme System; In Vitro Techniques; Inactivation, Metabolic; Liver; Male; Mutagens; NADPH-Ferrihemoprotein Reductase; Nitro Compounds; Phenobarbital; Polycyclic Compounds; Rats; Rats, Inbred Strains | 1985 |
Characterization of water-soluble glucuronide and sulphate conjugates of aflatoxin B1. 1. Urinary excretion in monkey, rat and mouse.
Topics: Aflatoxin B1; Aflatoxins; Animals; Autoradiography; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Glucuronates; Infusions, Parenteral; Injections, Intraperitoneal; Macaca mulatta; Male; Mice; Mutagenicity Tests; Phenobarbital; Rats; Rats, Inbred Strains; Salmonella typhimurium; Species Specificity; Sulfates | 1985 |
Effects of dietary selenium and vitamin E on covalent binding of aflatoxin to chick liver cell macromolecules.
Topics: Aflatoxin B1; Aflatoxins; Animals; Chickens; DNA; Eating; Female; Glutathione; Glutathione Peroxidase; Liver; Male; Phenobarbital; RNA; Selenium; Sex Factors; Vitamin E | 1982 |
The effect of phenobarbital pretreatment on the metabolism, covalent binding, and cytotoxicity of aflatoxin B1 in primary cultures of rat hepatocytes.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carbon Radioisotopes; Cells, Cultured; DNA; Drug Interactions; Glutathione Transferase; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; RNA | 1984 |
Molecular cloning and coding nucleotide sequence of complementary DNA of cytochrome P-450 involved in metabolic activation of carcinogenic substances.
Topics: Aflatoxin B1; Aflatoxins; Amino Acid Sequence; Animals; Base Sequence; Biotransformation; Carcinogens; Cloning, Molecular; Cytochrome P-450 Enzyme System; DNA; DNA Restriction Enzymes; Microsomes, Liver; Molecular Weight; Nucleic Acid Hybridization; Phenobarbital; Protein Biosynthesis; Rats | 1982 |
Long-term effects of neonatal phenobarbital exposure on aflatoxin b1 disposition in adult rats.
Topics: Aflatoxin B1; Aflatoxins; Age Factors; Animals; Animals, Newborn; Body Weight; DNA; Female; Liver; Male; Microsomes, Liver; Organ Size; Phenobarbital; Rats; Sex Factors | 1983 |
Preferential binding of aflatoxin B1 to the transcriptionally active regions of rat liver nucleolar chromatin in vivo and in vitro.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; Carcinogens; Cell Nucleolus; Chemical Phenomena; Chemistry; Chromatin; DNA-Directed RNA Polymerases; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred Strains; RNA Polymerase I; Transcription, Genetic | 1983 |
The metabolism of aflatoxin B1 by hepatocytes isolated from rats following the in vivo administration of some xenobiotics.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carbon Radioisotopes; Carcinogens; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred F344 | 1983 |
Correlation between mixed-function oxidase enzyme induction and aflatoxin B1-induced unscheduled DNA synthesis in the chick embryo, in vivo.
Topics: Aflatoxin B1; Aflatoxins; Animals; Chick Embryo; DNA; Enzyme Induction; Mixed Function Oxygenases; Phenobarbital; Polychlorinated Biphenyls | 1984 |
Experimental induction of chronic aflatoxicosis in chickens by purified aflatoxin B1 and its reversal by activated charcoal, phenobarbital, and reduced glutathione.
Topics: Aflatoxin B1; Aflatoxins; Animals; Aspartate Aminotransferases; Body Weight; Charcoal; Chickens; Chronic Disease; Cytochrome P-450 Enzyme System; Eating; Female; Foodborne Diseases; Glutathione; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Phenobarbital; Poultry Diseases | 1984 |
A comparison of the effects of pretreatment with phenobarbitone and 3-methylcholanthrene on the metabolism of aflatoxin B1 by rat liver microsomes and isolated hepatocytes in vitro.
Topics: Aflatoxin B1; Aflatoxins; Animals; Cytochrome P-450 Enzyme System; DNA; Liver; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Rats, Inbred F344 | 1981 |
Effect of sex differences on subcellular distribution of aflatoxin in F-344 rats treated with various risk-modifying factors.
Topics: Aflatoxin B1; Aflatoxins; Animals; Carcinogens; Dietary Proteins; Female; Liver; Male; Phenobarbital; Rats; Rats, Inbred F344; Sex Factors; Subcellular Fractions | 1981 |
Effects of phenobarbital pretreatment on the metabolism and toxicokinetics of aflatoxin B1 in the rhesus monkey.
Topics: Aflatoxin B1; Aflatoxins; Animals; Biotransformation; In Vitro Techniques; Kinetics; Liver; Macaca mulatta; Male; Mutagens; Phenobarbital; Protein Binding; Salmonella typhimurium | 1981 |
Metabolism and activation of aflatoxin B1 by reconstituted cytochrome P-450 system of rat liver.
Topics: Aflatoxin B1; Aflatoxin M1; Aflatoxins; Animals; Biotransformation; Cell Nucleus; Cytochrome P-450 Enzyme System; DNA; Hydrogen-Ion Concentration; Kinetics; Liver; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Polychlorinated Biphenyls; Rats | 1982 |
Effect of some enzyme inducers, fluids, and methionine-thiosulfate on induced acute aflatoxicosis in goats.
Topics: Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; beta-Naphthoflavone; Goats; Kidney; Liver; Male; Mortality; Phenobarbital; Phenylbutazone; Water | 1982 |
Effect of enzyme inducers and inhibitors and glutathione precursor and depleter on induced acute aflatoxicosis in rabbits.
Topics: Acute Disease; Aflatoxin B1; Aflatoxins; Animals; Benzoflavones; Carcinogens; Chlorides; Cobalt; Cysteine; Enzyme Induction; Enzyme Inhibitors; Glutathione; Goats; Liver; Male; Maleates; Microsomes, Liver; Phenobarbital; Phenylbutazone; Piperonyl Butoxide; Rabbits; Rats; Stanozolol | 1982 |
Effect of senescence on the bioactivation of aliphatic halides.
Topics: Aflatoxin B1; Aflatoxins; Aging; Animals; Biotransformation; Enzyme Induction; Hydrocarbons, Halogenated; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Inbred F344 | 1982 |
[Effect of aflatoxin B1 on monooxygenase activity in liver microsomes exposed to cytochrome P-450].
Topics: 7-Alkoxycoumarin O-Dealkylase; Aflatoxin B1; Aminopyrine N-Demethylase; Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Rats, Wistar | 1994 |
Characterization of cytochrome P450-monooxygenases of Chinese hamsters with respect to aflatoxin B1 activation.
Topics: Aflatoxin B1; Animals; Biotransformation; Cricetinae; Cricetulus; Cytochrome P-450 Enzyme System; Female; Isoenzymes; Male; Mesocricetus; Phenobarbital; Species Specificity | 1994 |
Association between responsiveness to phenobarbital induction of CYP2B1/2 and 3A1 in rat hepatic hyperplastic nodules and their zonal origin.
Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Hyperplasia; Liver; Liver Neoplasms, Experimental; Male; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344 | 1993 |
Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes.
Topics: Aflatoxin B1; Animals; Blotting, Western; Coumarins; Cricetinae; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phenobarbital; Pyrazoles; Steroid Hydroxylases | 1994 |
The primary and secondary metabolism of aflatoxin B1 by rat hepatocytes cultured on matrigel.
Topics: Aflatoxin B1; Animals; Biocompatible Materials; Biotransformation; Blotting, Western; Cells, Cultured; Collagen; Culture Media; Cytochrome P-450 Enzyme System; Drug Combinations; Glutathione Transferase; Laminin; Liver; Male; Microsomes, Liver; Phenobarbital; Proteoglycans; Rats; Rats, Inbred F344 | 1994 |
Regulation of aflatoxin B1-metabolizing aldehyde reductase and glutathione S-transferase by chemoprotectors.
Topics: Aflatoxin B1; Aldehyde Reductase; Animals; Anticarcinogenic Agents; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Clofibrate; Enzyme Induction; Ethoxyquin; Glutathione Transferase; Isoenzymes; Liver; Male; Methylcholanthrene; Phenobarbital; Rats; Rats, Inbred F344; Tissue Distribution; Xenobiotics | 1994 |
Glutathione S-transferase isoenzyme patterns in different subtypes of enzyme-altered rat liver foci treated with the peroxisome proliferator nafenopin or with phenobarbital.
Topics: Adenoma; Aflatoxin B1; Animals; Carcinogens; Female; Glutathione Transferase; Isoenzymes; Liver; Liver Neoplasms, Experimental; Macromolecular Substances; Male; Microbodies; Nafenopin; Phenobarbital; Rats; Rats, Wistar | 1993 |
Induction of rat liver GSH transferases by 1,2-dithiole-3-thione illustrates both anticarcinogenic and tumor-promoting properties.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Chromatography, Affinity; Chromatography, High Pressure Liquid; Cytosol; Enzyme Induction; Glutathione Transferase; Inactivation, Metabolic; Liver; Macromolecular Substances; Phenobarbital; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes | 1993 |
Modulation of aflatoxin B1-induced glutathione S-transferase placental form positive hepatic foci by pretreatment of rats with phenobarbital and buthionine sulfoximine.
Topics: Aflatoxin B1; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; DNA; Drug Interactions; Enzyme Induction; Glutathione Transferase; Liver; Male; Methionine Sulfoximine; Phenobarbital; Rats; Rats, Inbred F344 | 1993 |
Human liver S-9 metabolic activation: proficiency in cytogenetic assays and comparison with phenobarbital/beta-naphthoflavone or aroclor 1254 induced rat S-9.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; beta-Naphthoflavone; Biotransformation; Chlorodiphenyl (54% Chlorine); CHO Cells; Cricetinae; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Enzyme Induction; Humans; Liver; Mutagenicity Tests; Mutagens; Phenobarbital; Rats | 1996 |
Lack of tumor-promoting effects of flavonoids: studies on rat liver preneoplastic foci and on in vivo and in vitro gap junctional intercellular communication.
Topics: 2-Acetylaminofluorene; Aflatoxin B1; Animals; Carcinogens; Cell Line; Cricetinae; Flavanones; Flavones; Flavonoids; Gap Junctions; Glutathione Transferase; Hepatectomy; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Quercetin; Rats; Rats, Wistar | 1996 |
Potentiation of aflatoxin B1-induced hepatocarcinogenesis in the rat by pretreatment with buthionine sulfoximine.
Topics: Aflatoxin B1; Animals; Buthionine Sulfoximine; Carcinogens; Drug Synergism; Enzyme Inhibitors; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms; Male; Neoplasms, Experimental; Phenobarbital; Rats; Rats, Inbred F344; Time Factors | 1997 |
2-(Allylthio)pyrazine inhibition of aflatoxin B1-induced hepatocarcinogenesis in rats.
Topics: Aflatoxin B1; Animals; Carcinogenicity Tests; DNA Adducts; DNA, Neoplasm; Enzyme Inhibitors; Glutathione Transferase; Hepatectomy; Immunoenzyme Techniques; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Pyrazines; Rats; Rats, Sprague-Dawley; RNA | 1999 |
Effects of aflatoxin B1 on the hepatic microsomal mixed function oxidase system during phenobarbital and benzo(a)pyrene treatment in chickens.
Topics: Aflatoxin B1; Animals; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Carcinogens; Chickens; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Drug Interactions; Enzyme Induction; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Steroid Hydroxylases | 1999 |
Regulation of rat glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) subunits by chemopreventive agents and in aflatoxin B(1)-induced preneoplasia.
Topics: 4-Butyrolactone; Aflatoxin B1; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Catalytic Domain; Coumarins; Diet; Ellagic Acid; Enzyme Induction; Ethoxyquin; Glutamate-Cysteine Ligase; Glutathione; Inactivation, Metabolic; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Wistar | 2000 |
Mechanisms involved in the chemoprevention of flavonoids.
Topics: Aflatoxin B1; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Cytosol; Diet; DNA; Flavanones; Flavones; Flavonoids; Glutathione; Liver; Liver Neoplasms, Experimental; Male; Phenobarbital; Quercetin; Rats; Rats, Wistar | 2000 |
Involvement of mu class glutathione S-transferase subunit M2 (rGST M2) levels in the initiation and promotion of hepatocellular carcinogenesis in old rats.
Topics: Aflatoxin B1; Aging; Animals; Carcinogens; Glutathione Transferase; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Phenobarbital; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Protein Subunits; Rats; Rats, Wistar | 2001 |
Integrated plastic microfluidic devices with ESI-MS for drug screening and residue analysis.
Topics: Aflatoxin B1; Aflatoxins; Antibodies, Monoclonal; Barbiturates; Drug Evaluation, Preclinical; Drug Residues; Filtration; Food Contamination; Membranes, Artificial; Phenobarbital; Polyesters; Siloxanes; Spectrometry, Mass, Electrospray Ionization; Vinyl Compounds | 2001 |
Toxicity of aflatoxin B1 to Helicoverpa zea and bioactivation by cytochrome P450 monooxygenases.
Topics: Aflatoxin B1; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; Inactivation, Metabolic; Insecticide Resistance; Larva; Lepidoptera; Pesticide Synergists; Phenobarbital; Piperonyl Butoxide; Toxicity Tests | 2006 |
Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK6 cells.
Topics: Activation, Metabolic; Aflatoxin B1; Animals; Apoptosis; Benzo(a)pyrene; Cell Line; Cell Survival; Cisplatin; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Profiling; Genetic Markers; Humans; Micronucleus Tests; Mutagens; Phenobarbital; Rats; Reproducibility of Results; Toxicogenetics | 2015 |