phenobarbital has been researched along with 7-ethoxycoumarin in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (55.00) | 18.7374 |
| 1990's | 8 (40.00) | 18.2507 |
| 2000's | 1 (5.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gann, KL; Jauregui, HO; Ng, SF; Waxman, DJ | 1 |
| Fujino, T; Gelboin, HV; Park, SS; West, D | 1 |
| Heubel, F; Netter, KJ; Vesell, ES | 1 |
| Legrum, W; Meyer, S | 1 |
| Karge, E; Klinger, W | 1 |
| Graf, H; Jung, B; Ullrich, V | 1 |
| Adams, DJ; Dawson, JR; Wolf, CR | 1 |
| Greiling, H; Greiling, K; Klinger, W; Müller, D | 1 |
| Adams, DJ; Amelizad, Z; Oesch, F; Seilman, S; Wolf, CR | 1 |
| Fry, JR; Horner, SA; Paterson, P | 1 |
| Betnér, I; Halpert, J; Näslund, B | 1 |
| Crisp, DN; Orton, TC; Sorman, AE; Sturdee, AP | 1 |
| Hines, RN; Nelson, RE; Prough, RA; Sieg, MS; Wiebkin, P | 1 |
| Clement, B; Mladek, C | 1 |
| Bunch, AW; Fernandez-Salguero, P; Gutierrez-Merino, C | 1 |
| Grimm, SW; Halpert, JR; Kedzie, KM; Philpot, RM; Ryan, R | 1 |
| Jansson, I; Schenkman, JB | 1 |
| Chikaoka, Y; Tamura, M | 1 |
| Carlile, DJ; Hakooz, N; Houston, JB | 1 |
| Etzrodt, J; Glöckner, R; Lupp, A; Müller, D | 1 |
20 other study(ies) available for phenobarbital and 7-ethoxycoumarin
| Article | Year |
|---|---|
Xenobiotic induction of P-450 PB-4 (IIB1) and P-450c (IA1) and associated monooxygenase activities in primary cultures of adult rat hepatocytes.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Blotting, Western; Cells, Cultured; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Diazepam; Enzyme Induction; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Xenobiotics | 1991 |
Studies on the mechanism of monoclonal antibody inhibition of enzyme activity of phenobarbital-induced cytochrome P-450.
Topics: Animals; Antibodies, Monoclonal; Benzphetamine; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethylmorphine; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats; Rats, Inbred Strains | 1990 |
Brief maternal deprivation of rats reduces hepatic mixed function oxidase activities.
Topics: Aminopyrine; Animals; Benzphetamine; Biotransformation; Body Weight; Coumarins; Enzyme Induction; Female; Handling, Psychological; Male; Maternal Deprivation; Microsomes, Liver; Mixed Function Oxygenases; Oxazines; Phenobarbital; Rats; Rats, Inbred Strains | 1989 |
The combinations of inducers of the coumarin hydroxylase-locus help investigate their mode of action.
Topics: Amitrole; Animals; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Induction; Liver; Male; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Phenobarbital; Pyrazines; Pyrazoles | 1989 |
Interaction of induction, ontogenetic development and liver regeneration on the monooxygenase level.
Topics: Age Factors; Aging; Animals; Benzoflavones; beta-Naphthoflavone; Body Weight; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethylmorphine; Hepatectomy; Liver; Liver Regeneration; Male; Phenobarbital; Rats; Rats, Inbred Strains | 1987 |
A new monooxygenase product from 7-ethoxycoumarin and its relation to the O-dealkylation reaction.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Coumarins; Cytochrome b Group; Cytochromes b5; Enzyme Induction; Hydroxylation; Isoenzymes; Mice; Microsomes, Liver; Mixed Function Oxygenases; NAD; NADP; Oxygenases; Phenobarbital; Rabbits; Rats; Rats, Inbred Strains; Species Specificity; Substrate Specificity; Swine; Time Factors | 1985 |
Induction of drug metabolizing enzymes in human liver cell line Hep G2.
Topics: Cell Line; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronosyltransferase; Humans; Isoenzymes; Liver; Methylcholanthrene; Pharmaceutical Preparations; Phenobarbital; Sulfurtransferases | 1985 |
The influence of triiodothyronine (T3) and inducers on hepatic drug metabolism in rats of different ages.
Topics: Age Factors; Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Coumarins; Cytochrome P-450 Enzyme System; Ethylmorphine; Liver; Male; Phenobarbital; Rats; Rats, Inbred Strains; Triiodothyronine | 1985 |
Identification of human cytochromes P-450 analogous to forms induced by phenobarbital and 3-methylcholanthrene in the rat.
Topics: Animals; Antibodies; Coumarins; Cytochrome P-450 Enzyme System; Humans; Isoenzymes; Methylcholanthrene; Microsomes, Liver; Oxazines; Phenobarbital; Rats; Rats, Inbred Strains; Species Specificity | 1985 |
Influence of cytochrome P-450 type on the pattern of conjugation of 7-hydroxycoumarin generated from 7-alkoxycoumarins.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Coumarins; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Induction; Ethanol; In Vitro Techniques; Kinetics; Male; Metyrapone; Microsomes, Liver; Oxazoles; Phenobarbital; Rats; Rats, Inbred Strains; Substrate Specificity; Umbelliferones | 1984 |
Suicide inactivation of rat liver cytochrome P-450 by chloramphenicol in vivo and in vitro.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Benzene Derivatives; Chloramphenicol; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Iodobenzoates; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH Oxidases; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
Dynamics of xenobiotic metabolism by isolated rat hepatocytes using a multichannel perifusion system.
Topics: Aldrin; Animals; Biochemistry; Biotransformation; Coumarins; Equipment Design; In Vitro Techniques; Liver; Male; Metyrapone; Mixed Function Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains | 1983 |
Inhibition of metabolism-mediated cytotoxicity by 1,1-disubstituted hydrazines in mouse mastocytoma (line P815) cells.
Topics: Animals; Biotransformation; Cell Survival; Cells, Cultured; Coumarins; Cyclophosphamide; Hydrazines; Liver; Male; Mast-Cell Sarcoma; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Sarcoma, Experimental | 1982 |
[Biotransformation processes in fertile hen's eggs. 1. Metabolic transformation of 7-ethoxycoumarin].
Topics: Animals; Biotransformation; Chick Embryo; Chromatography, High Pressure Liquid; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucuronates; Methylcholanthrene; Ovalbumin; Phenobarbital; Sulfates | 1995 |
Effect of immobilization on the activity of rat hepatic microsomal cytochrome P450 enzymes.
Topics: Animals; Biotransformation; Coumarins; Cytochrome P-450 Enzyme System; Cytochromes b5; Enzymes, Immobilized; Male; Membranes, Artificial; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats; Rats, Inbred Strains; Rats, Wistar; Umbelliferones | 1993 |
Cloning, sequencing, and functional studies of phenobarbital-inducible forms of cytochrome P450 2B and 4B expressed in rabbit kidney.
Topics: Amino Acid Sequence; Androstenedione; Animals; Base Sequence; Cloning, Molecular; Coumarins; Cytochrome P-450 Enzyme System; DNA Probes; Enzyme Induction; Kidney; Molecular Sequence Data; Phenobarbital; Rabbits; Recombinant Proteins; RNA, Messenger; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Species Specificity; Steroid Hydroxylases; Tissue Distribution | 1993 |
Substrate influence on interaction between cytochrome P450 and cytochrome b5 in microsomes.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; beta-Naphthoflavone; Coumarins; Cross-Linking Reagents; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Cytochromes b5; Ethyldimethylaminopropyl Carbodiimide; In Vitro Techniques; Microsomes, Liver; Oxidoreductases; Phenobarbital; Rabbits; Steroid Hydroxylases; Substrate Specificity | 1996 |
7-ethoxycoumarin deethylation activity in perfused isolated rat brain.
Topics: Animals; beta-Naphthoflavone; Brain; Coumarins; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Male; Perfusion; Phenobarbital; Rats; Rats, Wistar | 1999 |
Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity.
Topics: Animals; beta-Naphthoflavone; Cell Separation; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles | 1999 |
Precision-cut liver slices from rats of different ages: basal cytochrome P450-dependent monooxygenase activities and inducibility.
Topics: Aging; Animals; Anti-Inflammatory Agents; beta-Naphthoflavone; Coumarins; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Dexamethasone; Dimethyl Sulfoxide; Enzyme Induction; Enzyme Inhibitors; Hydroxylation; Liver; Male; Mixed Function Oxygenases; Organ Culture Techniques; Oxazines; Phenobarbital; Pregnenolone Carbonitrile; Rats; Rats, Wistar; Testosterone; Time Factors | 2008 |