phenobarbital has been researched along with 6 beta-hydroxycortisol in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (72.22) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hildebrandt, AG; Kewitz, H; Roots, I; Saalfrank, K; Speck, M | 1 |
| Breckenridge, AM; Kitteringham, NR; Park, BK; Pirmohamed, M | 1 |
| Yakata, M | 1 |
| Breckenridge, AM; Ohnhaus, EE; Park, BK | 1 |
| Feely, MP; Hay, A; Mehta, A; Park, BK; Price, DE | 1 |
| Eichelbaum, M; Mineshita, S; Ohnhaus, EE; Zekorn, C | 1 |
| Saenger, P | 1 |
| Kaatz, G; Ohnhaus, EE; Park, BK; Wilson, AC | 1 |
| Challiner, MR; Newby, S; Park, BK | 1 |
| Gerber-Taras, E; Ohnhaus, EE; Park, BK | 2 |
| Challiner, MR; Odum, J; Orton, TC; Park, BK; Parker, GL | 1 |
| Forster, E; Kream, J; Saenger, P | 1 |
| Charles, B; Harada, T; Inokuma, M; Inoue, S; Ishida, J; Shibutani, Y; Yamaguchi, M; Yoshitake, T | 1 |
| Boucher, JL; de Lauture, D; Delaforge, M; Joseph, X; Kahan, A; Lejus, C; Pinquier, JL; Strauch, G | 1 |
| Deutsch, PJ; Goldberg, MR; Lo, MW; McCrea, JB; McWilliams, EJ; Wilson, SE | 1 |
| BURSTEIN, S; KLAIBER, EL | 1 |
| Lang, LM; Linnet, K | 1 |
2 trial(s) available for phenobarbital and 6 beta-hydroxycortisol
| Article | Year |
|---|---|
Evaluation of in vivo parameters of drug metabolizing enzyme activity in man after administration of clemastine, phenobarbital or placebo.
Topics: 17-Hydroxycorticosteroids; Adult; Aminopyrine; Clinical Trials as Topic; Drug Evaluation; Enzyme Induction; gamma-Glutamyltransferase; Glucaric Acid; Half-Life; Humans; Hydrocortisone; Kinetics; Male; Phenobarbital; Placebos | 1975 |
Phenobarbital minimally alters plasma concentrations of losartan and its active metabolite E-3174.
Topics: Adult; Anticonvulsants; Antihypertensive Agents; Biphenyl Compounds; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Hydrocortisone; Hypnotics and Sedatives; Imidazoles; Losartan; Male; Mixed Function Oxygenases; Phenobarbital; Reference Values; Single-Blind Method; Tetrazoles | 1996 |
16 other study(ies) available for phenobarbital and 6 beta-hydroxycortisol
| Article | Year |
|---|---|
The effect of enzyme induction on the cytochrome P450-mediated bioactivation of carbamazepine by mouse liver microsomes.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Biotransformation; Carbamazepine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Hydrocortisone; Immunoblotting; Male; Mice; Mice, Inbred CBA; Microsomes, Liver; Norpregnenes; Phenobarbital | 1992 |
[Clinical significance of urinary 6 beta-hydroxycortisol analysis in endocrine tests of the adrenal cortex].
Topics: Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Cushing Syndrome; Female; Humans; Hydrocortisone; Infant; Infant, Newborn; Male; Middle Aged; Phenobarbital; Reference Values; Sex Factors; Specimen Handling | 1989 |
Urinary excretion of 6 beta-hydroxycortisol and the time course measurement of enzyme induction in man.
Topics: Adult; Antipyrine; Enzyme Induction; Female; Humans; Hydrocortisone; Kinetics; Liver; Male; Mixed Function Oxygenases; Phenobarbital; Rifampin; Time Factors | 1989 |
The effect of low-dose phenobarbitone on three indices of hepatic microsomal enzyme induction.
Topics: Adult; Antipyrine; Dose-Response Relationship, Drug; Enzyme Induction; Female; Glucaric Acid; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Microsomes, Liver; Phenobarbital | 1986 |
The influence of enzyme induction on polymorphic sparteine oxidation.
Topics: Adult; Antipyrine; Enzyme Induction; Female; Half-Life; Humans; Hydrocortisone; Male; Metabolic Clearance Rate; Middle Aged; Oxidation-Reduction; Phenobarbital; Rifampin; Sparteine | 1986 |
6 beta-hydroxycortisol in random urine samples as an indicator of enzyme induction.
Topics: Child; Child, Preschool; Circadian Rhythm; Enzyme Induction; Female; Humans; Hydrocortisone; Male; Mixed Function Oxygenases; Phenobarbital | 1983 |
Enzyme induction by phenobarbitone and vitamin K1 disposition in man.
Topics: Antipyrine; Enzyme Induction; Female; Half-Life; Humans; Hydrocortisone; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Vitamin K 1 | 1984 |
The effects of phenobarbitone on urinary 6 beta-hydroxycortisol excretion and hepatic enzyme activity in the guinea-pig.
Topics: Adrenal Cortex Hormones; Animals; Body Weight; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Guinea Pigs; Hydrocortisone; Liver; Male; Microsomes, Liver; NADH Dehydrogenase; Organ Size; Phenobarbital | 1983 |
Enzyme-inducing drug combinations and their effects on liver microsomal enzyme activity in man.
Topics: Adult; Antipyrine; Drug Combinations; Enzyme Induction; Female; Humans; Hydrocortisone; Male; Microsomes, Liver; Phenobarbital; Rifampin | 1983 |
The effects of phenobarbitone on urinary 6 beta-hydroxycortisol excretion and hepatic enzyme activity in the marmoset monkey (Callithrix jacchus).
Topics: 17-Hydroxycorticosteroids; 7-Alkoxycoumarin O-Dealkylase; Animals; Callithrix; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydrocortisone; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Oxygenases; Phenobarbital | 1980 |
The estimation of 6 beta-hydroxycortisol in urine -- a comparison of two methods: high performance liquid chromatography and radioimmunoassay.
Topics: Antipyrine; Chromatography, High Pressure Liquid; Humans; Hydrocortisone; Phenobarbital; Radioimmunoassay; Rifampin | 1981 |
6 beta-Hydroxycortisol: a noninvasive indicator of enzyme induction.
Topics: 17-Hydroxycorticosteroids; Child; Child, Preschool; Enzyme Induction; Female; Humans; Hydrocortisone; Male; Phenobarbital; Phenytoin; Radioimmunoassay | 1981 |
Simultaneous high-performance liquid chromatographic determination of 6 beta-hydroxycortisol and cortisol in urine with fluorescence detection and its application for estimating hepatic drug-metabolizing enzyme induction.
Topics: Administration, Oral; Animals; Calibration; Chromatography, High Pressure Liquid; Enzyme Induction; Female; Fluorescence; Humans; Hydrocortisone; Macaca mulatta; Male; Microsomes, Liver; Phenobarbital; Reproducibility of Results | 1994 |
Lack of effect of phenobarbital on ex vivo leukocyte oxidative metabolism in healthy volunteers.
Topics: 17-Hydroxycorticosteroids; Adult; Biomarkers; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Hydrocortisone; Leukotriene B4; Male; Neutrophils; Oxidation-Reduction; Phenobarbital | 1993 |
PHENOBARBITAL-INDUCED INCREASE IN 6-BETA-HYDROXYCORTISOL EXCRETION: CLUE TO ITS SIGNIFICANCE IN HUMAN URINE.
Topics: Adrenal Cortex Hormones; Biomedical Research; Hydrocortisone; Pharmacology; Phenobarbital; Spectrum Analysis; Urine | 1965 |
The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers; Carbamazepine; Child; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Female; Forensic Toxicology; Humans; Hydrocortisone; Liver Cirrhosis; Male; Middle Aged; Oxcarbazepine; Phenobarbital; Phenytoin; Young Adult | 2014 |