Compounds > phenobarbital

phenobarbital and 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde o-(3,4-dichlorobenzyl)oxime

phenobarbital has been researched along with 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde o-(3,4-dichlorobenzyl)oxime in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's9 (81.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eddington, ND; Hassan, HE; Lee, IJ; Mason, CW; Myers, AL; Sinz, MW; Wang, D; Wang, H1
Diethelm-Varela, B; Li, L; Liang, D; Lynch, C; Wang, H; Xia, M; Xue, F1
Friis, C; Gillberg, M; Skaanild, MT1
Boursier-Neyret, C; Cloarec, O; Croixmarie, V; Moreau, A; Pascussi, JM; Umbdenstock, T; Walther, B1
Breuker, C; Lakhal, L; Lumbroso, S; Maurel, P; Meyer, U; Moreau, A; Parmentier, Y; Pascussi, JM; Tamasi, V; Vilarem, MJ1
Hiramatsu, Y; Masuyama, H; Nakatsukasa, H1
Boursier-Neyret, C; Cloarec, O; Croixmarie, V; Moreau, A; Parmentier, Y; Pascussi, JM; Umbdenstock, T; Walther, B1
Garzel, B; Heyward, S; Moeller, T; Shapiro, P; Wang, H; Yang, H1
Brayman, TG; Huang, SM; Li, D; Mackowiak, B; Mitchell, M; Wang, H; Zhang, L1
Andersen, ME; Cowie, DE; Deisenroth, C; LeCluyse, E; Peffer, RC; Soldatow, V; Trask, OJ1
Briolotti, P; Daujat-Chavanieu, M; de Boussac, H; Duret, C; Fabre, JM; Gerbal-Chaloin, S; Gondeau, C; Herrero, A; Maurel, P; Ramos, J; Römer, M; Templin, M; Treindl, F1

Other Studies

11 other study(ies) available for phenobarbital and 6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde o-(3,4-dichlorobenzyl)oxime

ArticleYear
Induction of xenobiotic receptors, transporters, and drug metabolizing enzymes by oxycodone.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Animals; Cell Line, Tumor; Gene Expression; Humans; Liver; Male; Oxycodone; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, Drug; Transcriptional Activation; Xenobiotics

2013
DL5050, a Selective Agonist for the Human Constitutive Androstane Receptor.
    ACS medicinal chemistry letters, 2019, Jul-11, Volume: 10, Issue:7

    Topics:

2019
Regulation of gender-dependent CYP2A expression in pigs: involvement of androgens and CAR.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:5

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Constitutive Androstane Receptor; Coumarins; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Liver; Male; Orchiectomy; Oximes; Phenobarbital; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; RNA, Messenger; Sex Factors; Steroid Hydroxylases; Swine; Swine, Miniature; Thiazoles; Transcription Factors

2006
Integrated comparison of drug-related and drug-induced ultra performance liquid chromatography/mass spectrometry metabonomic profiles using human hepatocyte cultures.
    Analytical chemistry, 2009, Aug-01, Volume: 81, Issue:15

    Topics: Biomarkers; Chromatography, Liquid; Constitutive Androstane Receptor; Excitatory Amino Acid Antagonists; Hepatocytes; Humans; Mass Spectrometry; Metabolomics; Nucleic Acid Synthesis Inhibitors; Oximes; Phenobarbital; Rifampin; Thiazoles

2009
Hepatic expression of thyroid hormone-responsive spot 14 protein is regulated by constitutive androstane receptor (NR1I3).
    Endocrinology, 2010, Volume: 151, Issue:4

    Topics: Adult; Aged; Analysis of Variance; Animals; Blotting, Western; Cells, Cultured; Constitutive Androstane Receptor; Electrophoretic Mobility Shift Assay; Female; Gene Expression Regulation; Humans; Liver; Male; Mice; Middle Aged; Nuclear Proteins; Oximes; Phenobarbital; Promoter Regions, Genetic; Pyridines; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thiazoles; Transcription Factors; Transcriptional Activation; Transfection

2010
Effect of oncostatin M on uridine diphosphate-5'-glucuronosyltransferase 1A1 through cross talk with constitutive androstane receptor.
    Molecular endocrinology (Baltimore, Md.), 2010, Volume: 24, Issue:4

    Topics: Animals; Animals, Newborn; Blotting, Western; Constitutive Androstane Receptor; Cytochrome P-450 CYP3A; Flavonoids; Glucuronosyltransferase; Hep G2 Cells; Humans; Infant, Newborn; Jaundice, Neonatal; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinases; Oncostatin M; Oximes; Phenobarbital; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Thiazoles

2010
Metabonomic studies on human hepatocyte in primary culture.
    Methods in molecular biology (Clifton, N.J.), 2010, Volume: 640

    Topics: Cells, Cultured; Constitutive Androstane Receptor; Hepatocytes; Humans; Mass Spectrometry; Metabolomics; Models, Biological; Oximes; Phenobarbital; Pregnane X Receptor; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Rifampin; Thiazoles

2010
Metformin represses drug-induced expression of CYP2B6 by modulating the constitutive androstane receptor signaling.
    Molecular pharmacology, 2014, Volume: 85, Issue:2

    Topics: Active Transport, Cell Nucleus; AMP-Activated Protein Kinases; Aryl Hydrocarbon Hydroxylases; Constitutive Androstane Receptor; Cytochrome P-450 CYP2B6; Dose-Response Relationship, Drug; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Hypoglycemic Agents; Metformin; Oximes; p38 Mitogen-Activated Protein Kinases; Phenobarbital; Phosphorylation; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thiazoles

2014
Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells.
    Biochemical pharmacology, 2015, Nov-01, Volume: 98, Issue:1

    Topics: Constitutive Androstane Receptor; Excitatory Amino Acid Antagonists; Gene Deletion; Gene Expression Regulation; Genome-Wide Association Study; Humans; Oximes; Phenobarbital; Receptors, Cytoplasmic and Nuclear; Thiazoles; Transcriptome

2015
Development of an in vitro high content imaging assay for quantitative assessment of CAR-dependent mouse, rat, and human primary hepatocyte proliferation.
    Toxicology in vitro : an international journal published in association with BIBRA, 2016, Volume: 36

    Topics: Acetaminophen; Animals; Aryl Hydrocarbon Hydroxylases; Biological Assay; Cell Proliferation; Cell Survival; Cells, Cultured; Constitutive Androstane Receptor; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; DNA; Epidermal Growth Factor; Hepatocytes; Humans; Male; Membrane Proteins; Mice; Microscopy, Fluorescence; Oximes; Phenobarbital; Pyridines; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Species Specificity; Steroid Hydroxylases; Thiazoles

2016
Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:3

    Topics: Adult; Aged; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Female; Gene Expression Regulation; Hepatocytes; Humans; Male; Middle Aged; Oximes; Peroxisome-Targeting Signal 1 Receptor; Phenobarbital; Recoverin; Signal Transduction; Thiazoles; Transcription, Genetic

2018