phenobarbital and 1-aminobenzotriazole

phenobarbital has been researched along with 1-aminobenzotriazole in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's6 (60.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bend, JR; Knickle, LC2
Bend, JR; Woodcroft, KJ1
Catto, L; Jones, RB; Leonard, T; Poole, A; Pritchard, D1
Costa, AK; Ortiz de Montellano, PR1
Bend, JR; Grimm, SW; Halpert, JR1
Bend, JR; Knickle, LC; Philpot, RM1
Carlile, DJ; Hakooz, N; Houston, JB1
Abbott, FS; Chang, TK; Chen, J; Tong, V1
Abbott, FS; Chang, TK; Surendradoss, J1

Other Studies

10 other study(ies) available for phenobarbital and 1-aminobenzotriazole

ArticleYear
Dose-dependent, mechanism-based inactivation of cytochrome P450 monooxygenases in vivo by 1-aminobenzotriazole in liver, lung, and kidney of untreated, phenobarbital-treated, and beta-naphthoflavone-treated guinea pigs.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:12

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Guinea Pigs; Isoenzymes; Kidney; Liver; Lung; Male; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Triazoles

1992
N-aralkylated derivatives of 1-aminobenzotriazole as isozyme-selective, mechanism-based inhibitors of guinea pig hepatic cytochrome P-450 dependent monooxygenase activity.
    Canadian journal of physiology and pharmacology, 1990, Volume: 68, Issue:9

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Isoenzymes; Kinetics; Liver; Male; Microsomes, Liver; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Triazoles

1990
In vitro accumulation of thyroid hormones by cultured rat hepatocytes and the biliary excretion of iodothyronines in rats treated with a novel histamine H2-receptor antagonist.
    Toxicology, 1989, Volume: 59, Issue:1

    Topics: Animals; Bile; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Histamine H2 Antagonists; Liver; Male; Phenobarbital; Pyrimidinones; Rats; Rats, Inbred Strains; Temperature; Thyroid Hormones; Thyroxine; Triazoles; Triiodothyronine

1989
Dissociation of cytochrome P-450 inactivation and induction.
    Archives of biochemistry and biophysics, 1986, Volume: 251, Issue:2

    Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Protein Biosynthesis; Rats; Rats, Inbred Strains; RNA, Messenger; Triazoles

1986
Selectivity and kinetics of inactivation of rabbit hepatic cytochromes P450 2B4 and 2B5 by N-aralkylated derivatives of 1-aminobenzotriazole.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:5

    Topics: Alkylation; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Cytochrome P-450 Enzyme System; Enzyme Activation; Humans; Isoenzymes; Kidney; Kinetics; Liver; Mice; Microsomes, Liver; Phenobarbital; Rabbits; Recombinant Proteins; Steroid Hydroxylases; Triazoles

1995
Bioactivation of arachidonic acid by the cytochrome P450 monooxygenases of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for formation of epoxyeicosatrienoic acids.
    Molecular pharmacology, 1994, Volume: 45, Issue:6

    Topics: 8,11,14-Eicosatrienoic Acid; Animals; Arachidonic Acid; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Guinea Pigs; Lung; Male; Metyrapone; Microsomes; Microsomes, Liver; NADP; Phenobarbital; Proadifen; Triazoles

1994
N-aralkylated derivatives of 1-aminobenzotriazole are potent isozyme- and lung-selective mechanism-based inhibitors of guinea pig cytochrome P-450 in vivo.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Guinea Pigs; Isoenzymes; Liver; Lung; Male; Phenobarbital; Sensitivity and Specificity; Triazoles

1994
Kinetics of drug metabolism in rat liver slices: IV. Comparison of ethoxycoumarin clearance by liver slices, isolated hepatocytes, and hepatic microsomes from rats pretreated with known modifiers of cytochrome P-450 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 1999, Volume: 27, Issue:4

    Topics: Animals; beta-Naphthoflavone; Cell Separation; Coumarins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Kinetics; Liver; Male; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles

1999
The effect of valproic acid on hepatic and plasma levels of 15-F2t-isoprostane in rats.
    Free radical biology & medicine, 2003, Jun-01, Volume: 34, Issue:11

    Topics: Animals; Anticonvulsants; Biotransformation; Cytochrome P-450 Enzyme System; Dinoprost; Enzyme Inhibitors; F2-Isoprostanes; Gas Chromatography-Mass Spectrometry; Lipid Peroxides; Liver; Male; Oxidative Stress; Phenobarbital; Proadifen; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Triazoles; Valproic Acid

2003
Assessment of the role of in situ generated (E)-2,4-diene-valproic acid in the toxicity of valproic acid and (E)-2-ene-valproic acid in sandwich-cultured rat hepatocytes.
    Toxicology and applied pharmacology, 2012, Nov-01, Volume: 264, Issue:3

    Topics: Animals; Cell Culture Techniques; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Hepatocytes; Male; Molecular Structure; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles; Valproic Acid

2012