Page last updated: 2024-08-17

phenidone and bw-755c

phenidone has been researched along with bw-755c in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199024 (75.00)18.7374
1990's7 (21.88)18.2507
2000's1 (3.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bruneau, P; Delvare, C; Edwards, MP; McMillan, RM1
Casey, FB; Ferguson, EW; Gangell, SJ; Gordon, RJ; Heimann, MR; Hlasta, DJ; Jaeger, EP; Kullnig, RK1
Brooks, DW; Carter, GW; Dyer, RD; Holms, JH; Kerdesky, FA; Schmidt, SP1
Bermudez, J; Buckle, DR; Foster, KA; Markwell, RE; Smith, SA; Taylor, JF; Tedder, JM; Thody, VE; Webster, RA1
Carter, GW; Dyer, RD; Holms, JH; Mazdiyasni, H; Ratajczyk, JD; Summers, JB1
Battioni, JP; Cucurou, C; Mansuy, D; Nam, NH; Thang, DC1
Calixto, JB; Cruz, AB; Medeiros, YS; Yunes, RA; Zanini JĂșnior, JC1
Ardaillou, R; Bens, M; Guidet, B; Lacave, R; Nagamine, Y; Rondeau, E; Sraer, J; Sraer, JD1
Linssen, MJ; Lipponer, L; Seilnacht, W; Wilhelms, OH1
Conroy, MC; Kennedy, JA; Thueson, DO1
Goossens, JG; van Wauwe, JP1
Nadler, JL; Natarajan, R; Stern, N1
Boctor, AM; Burke, C; Hovinga, ME1
Kato, R; Nakadate, T; Uzumaki, H; Yamamoto, S1
Aked, D; Foster, SJ; Howarth, A; McCormick, ME1
Gryglewski, RJ; Moncada, S; Palmer, RM1
Hand, JM; Lewis, AJ; Schwalm, SF2
Kishore, NP; Rao, GH; White, JG1
Edwards, RH; Jackson, MJ; Wagenmakers, AJ1
Beckman, BS; Fisher, JW; King, L; Mason-Garcia, M; Nystuen, L1
Antonipillai, I; Horton, R; Nadler, J1
Battioni, JP; Biatry, B; Cucurou, C; Mansuy, D1
Beckman, B; Nystuen, L1
Carlson, RP; Chang, J; Lewis, AJ; O'Neill-Davis, L1
Chang, J; Cherney, ML; Lewis, AJ; Skowronek, MD1
Adams, T; Manley, G; Steiner, S1
Fung, LW; Marnett, LJ; Siedlik, PH1
Mitchell, HW1
Ishii, M; Kato, R; Nakadate, T; Yamamoto, S1
Chaudhuri, AK; Ghosh, TK; Sen, T1
Bhattacharjee, S; Dhara, AK; Nag Chaudhuri, AK; Pal, S; Sen, T1

Other Studies

32 other study(ies) available for phenidone and bw-755c

ArticleYear
Indazolinones, a new series of redox-active 5-lipoxygenase inhibitors with built-in selectivity and oral activity.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:3

    Topics: Administration, Oral; Animals; Chemical Phenomena; Chemistry; Dinoprostone; Dogs; Humans; Indazoles; Leukotriene B4; Lipoxygenase Inhibitors; Male; Methemoglobinemia; Methylation; Molecular Structure; Oxidation-Reduction; Rats; Rats, Inbred Strains; Stereoisomerism; Structure-Activity Relationship; Thromboxane B2

1991
5-Lipoxygenase inhibitors: the synthesis and structure-activity relationships of a series of 1-phenyl-3-pyrazolidinones.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Enzyme Inhibitors; Guinea Pigs; Lipoxygenase Inhibitors; Pyrazoles; Rats; Structure-Activity Relationship

1991
Synthesis and 5-lipoxygenase inhibitory activity of 5-hydroperoxy-6,8,11,14-eicosatetraenoic acid analogues.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:7

    Topics: Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Leukotrienes; Lipoxygenase Inhibitors; Rats; Structure-Activity Relationship

1987
Novel 1H-benzimidazol-4-ols with potent 5-lipoxygenase inhibitory activity.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:12

    Topics: Animals; Arachidonate Lipoxygenases; Benzimidazoles; Female; Lipoxygenase Inhibitors; Rats; Rats, Inbred Strains; SRS-A; Structure-Activity Relationship

1987
Hydroxamic acid inhibitors of 5-lipoxygenase.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:3

    Topics: Arachidonate Lipoxygenases; Cell Line; Hydroxamic Acids; Kinetics; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Molecular Conformation; Protein Binding; Structure-Activity Relationship

1987
Mechanisms of inactivation of lipoxygenases by phenidone and BW755C.
    Biochemistry, 1991, Sep-17, Volume: 30, Issue:37

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Arachidonate 5-Lipoxygenase; Ascorbic Acid; Catalase; Electron Spin Resonance Spectroscopy; Enzyme Activation; Ferric Compounds; Glycine max; Humans; Leukocytes; Lipoxygenase; Lipoxygenase Inhibitors; Oxidation-Reduction; Oxygen; Pyrazoles; Solanum tuberosum; Sulfhydryl Compounds; Superoxide Dismutase

1991
Extract and compounds obtained from Mandevilla velutina inhibit arachidonic acid-induced ear oedema in mice, but not rat stomach contraction.
    Prostaglandins, 1991, Volume: 41, Issue:5

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Dinoprostone; Edema; Female; In Vitro Techniques; Indomethacin; Isometric Contraction; Lipoxygenase Inhibitors; Male; Masoprocol; Mice; Muscle, Smooth; Plant Extracts; Pyrazoles; Rats; Stomach

1991
Nordihydroguaiaretic acid inhibits urokinase synthesis by phorbol myristate acetate-stimulated LLC-PK1 cells.
    Biochimica et biophysica acta, 1990, Nov-12, Volume: 1055, Issue:2

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Cell Line; Enzyme Precursors; Fatty Acids, Unsaturated; Isoquinolines; Kinetics; Masoprocol; Piperazines; Plasminogen Activators; Plasminogen Inactivators; Protein Kinase C; Pyrazoles; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator

1990
Nimesulide, indomethacin, BW 755 C, phenidon, mepacrin and nedocromil inhibit the activation of human and rat leucocytes.
    International journal of tissue reactions, 1990, Volume: 12, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Humans; In Vitro Techniques; Indomethacin; Leukocytes; Lipoxygenase Inhibitors; Luminescent Measurements; Nedocromil; Phospholipases A; Pyrazoles; Quinacrine; Quinolones; Rats; Sulfonamides

1990
Differential inhibition of histamine release from human basophils induced by antigen, anti-IgE or N-formyl-L-methionyl-L-leucyl-L-phenylalanine.
    International archives of allergy and applied immunology, 1985, Volume: 77, Issue:1-2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Antibodies, Anti-Idiotypic; Antigens; Basophils; Catechols; Cells, Cultured; Chromones; Histamine Release; Humans; Immunoglobulin E; Indoles; Indomethacin; Masoprocol; Meclofenamic Acid; N-Formylmethionine Leucyl-Phenylalanine; Oxazoles; Pyrazoles; Receptors, Fc; Receptors, Formyl Peptide; Receptors, IgE; Receptors, Immunologic; Tetrazoles

1985
Arabinogalactan- and dextran-induced ear inflammation in mice: differential inhibition by H1-antihistamines, 5-HT-serotonin antagonists and lipoxygenase blockers.
    Agents and actions, 1989, Volume: 28, Issue:1-2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Aprotinin; Astemizole; Benzimidazoles; Benzoquinones; Cinanserin; Cyproheptadine; Dextrans; Galactans; Histamine H1 Antagonists; Kinetics; Lipoxygenase Inhibitors; Male; Metergoline; Mice; Otitis; Piperidines; Pyrazoles; Quinones; Ritanserin; Serotonin Antagonists

1989
Specific action of the lipoxygenase pathway in mediating angiotensin II-induced aldosterone synthesis in isolated adrenal glomerulosa cells.
    The Journal of clinical investigation, 1987, Volume: 80, Issue:6

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Epoprostenol; Flavanones; Flavonoids; Lipoxygenase; Lipoxygenase Inhibitors; Male; Potassium; Pyrazoles; Rats; Stimulation, Chemical

1987
Arachidonic acid-induced pleurisy (ARIP): an in vivo model for testing 5-lipoxygenase inhibition.
    Methods and findings in experimental and clinical pharmacology, 1987, Volume: 9, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acids; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Pleurisy; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors

1987
Lipoxygenase inhibitors and cyclic AMP-mediated insulin secretion caused by forskolin, theophylline and dibutyryl cyclic AMP.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 233, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Bucladesine; Catechols; Colforsin; Cyclic AMP; Diterpenes; Indomethacin; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Lipoxygenase Inhibitors; Male; Masoprocol; Pyrazoles; Rats; Secretory Rate; Theophylline

1985
Leukocyte recruitment in the subcutaneous sponge implant model of acute inflammation in the rat is not mediated by leukotriene B1.
    Biochemical pharmacology, 1986, May-15, Volume: 35, Issue:10

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Acute Disease; Animals; Blood Proteins; Calcimycin; Chemotaxis, Leukocyte; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Flurbiprofen; Indomethacin; Inflammation; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Male; Prostaglandins E; Pyrazoles; Pyrazolones; Rats; Rats, Inbred Strains; Skin

1986
Mechanism of action of some inhibitors of endothelium-derived relaxing factor.
    Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:23

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cytochrome c Group; Dithiothreitol; Endothelium; Hydroquinones; In Vitro Techniques; Muscle, Smooth, Vascular; Nitric Oxide; Oxidation-Reduction; Pyrazoles; Pyrogallol; Superoxide Dismutase; Swine; Vasodilator Agents

1986
Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors.
    International archives of allergy and applied immunology, 1986, Volume: 79, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Catechols; Chlorpheniramine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrazoles; SRS-A; Trachea

1986
Differential effects of putative inhibitors on cytosolic and membrane associated platelet lipoxygenase.
    Prostaglandins, leukotrienes, and medicine, 1987, Volume: 26, Issue:3

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonate Lipoxygenases; Blood Platelets; Cell Membrane; Cytosol; Humans; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Prostaglandin Antagonists; Pyrazoles; Quercetin; Substrate Specificity; Umbelliferones

1987
Inhibition of leukotriene-induced contraction of guinea pig trachea by 5-lipoxygenase inhibitors.
    Prostaglandins, 1987, Volume: 33, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Guinea Pigs; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrazoles; SRS-A; Trachea

1987
Effect of inhibitors of arachidonic acid metabolism on efflux of intracellular enzymes from skeletal muscle following experimental damage.
    The Biochemical journal, 1987, Jan-15, Volume: 241, Issue:2

    Topics: 2,4-Dinitrophenol; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Creatine Kinase; Cyclooxygenase Inhibitors; Dinitrophenols; Female; In Vitro Techniques; Masoprocol; Muscles; Muscular Diseases; Phenylacetates; Prostaglandins; Pyrazoles; Rats; Rats, Inbred Strains

1987
The action of erythropoietin is mediated by lipoxygenase metabolites in murine fetal liver cells.
    Biochemical and biophysical research communications, 1987, Aug-31, Volume: 147, Issue:1

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxyanisole; Erythropoiesis; Erythropoietin; Hydroxyeicosatetraenoic Acids; Liver; Masoprocol; Meclofenamic Acid; Mice; Phosphatidylinositols; Pyrazoles

1987
Angiotensin feedback inhibition on renin is expressed via the lipoxygenase pathway.
    Endocrinology, 1988, Volume: 122, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Angiotensin II; Animals; Arachidonate 12-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acids; Cyclooxygenase Inhibitors; Epoprostenol; Flavanones; Flavonoids; Hydroxyeicosatetraenoic Acids; Kidney Cortex; Leukotrienes; Lipoxygenase Inhibitors; Male; Meclofenamic Acid; Potassium; Pyrazoles; Rats; Rats, Inbred Strains; Renin

1988
Soybean lipoxygenase-catalyzed oxidations by linoleic acid hydroperoxide: different reducing substrates and dehydrogenation of phenidone and BW 755C.
    Biochemical and biophysical research communications, 1988, Feb-29, Volume: 151, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Catalysis; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Glycine max; Linoleic Acids; Lipid Peroxides; Lipoxygenase; Oxidation-Reduction; Pyrazoles; Spectrophotometry, Ultraviolet; Substrate Specificity

1988
Comparative effects of inhibitors of arachidonic acid metabolism on erythropoiesis.
    Prostaglandins, leukotrienes, and essential fatty acids, 1988, Volume: 31, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Butylated Hydroxyanisole; Cyclooxygenase Inhibitors; Erythropoiesis; Hematopoietic Stem Cells; Lipoxygenase Inhibitors; Masoprocol; Meclofenamic Acid; Mice; Pyrazoles

1988
Modulation of mouse ear edema by cyclooxygenase and lipoxygenase inhibitors and other pharmacologic agents.
    Agents and actions, 1985, Volume: 17, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Administration, Oral; Administration, Topical; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Edema; Female; Lipoxygenase Inhibitors; Methylprednisolone; Mice; Mice, Inbred Strains; Otitis Externa; Pyrazoles; Tetradecanoylphorbol Acetate

1985
Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations.
    Inflammation, 1984, Volume: 8, Issue:2

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Neutrophils; Pyrazoles; Quercetin; Rats

1984
Effect of inhibitors of the lipoxygenase pathway on mouse myoblast fusion.
    Experimental cell research, 1984, Volume: 155, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Cell Fusion; Cells, Cultured; Cyclooxygenase Inhibitors; Indomethacin; Lipoxygenase Inhibitors; Mice; Muscles; Pyrazoles; Umbelliferones

1984
Oxidation of phenidone and BW755C by prostaglandin endoperoxide synthetase.
    The Journal of biological chemistry, 1982, Jun-25, Volume: 257, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Kinetics; Male; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Seminal Vesicles; Sheep; Spectrophotometry; Substrate Specificity

1982
The effect of mixed inhibitors of cyclo-oxygenase and lipoxygenase on the indomethacin-induced hyper-reactivity in the isolated trachea of the pig.
    British journal of pharmacology, 1982, Volume: 77, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Airway Resistance; Animals; Cyclooxygenase Inhibitors; Histamine; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Muscle Contraction; Muscle, Smooth; Pyrazoles; Swine; Trachea

1982
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced epidermal ornithine decarboxylase activity by lipoxygenase inhibitors: possible role of product(s) of lipoxygenase pathway.
    Carcinogenesis, 1982, Volume: 3, Issue:12

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Carboxy-Lyases; Dinoprostone; Female; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Mice; Ornithine Decarboxylase Inhibitors; Phorbols; Prostaglandins E; Pyrazoles; Skin; Tetradecanoylphorbol Acetate

1982
Glucose oxidase-induced lysis of erythrocytes.
    Indian journal of experimental biology, 1995, Volume: 33, Issue:1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Glucose Oxidase; Hemolysis; Hydrogen Peroxide; Lipoxygenase Inhibitors; Pyrazoles; Rats

1995
Antioxidant activity of the methanol fraction of Pluchea indica root extract.
    Phytotherapy research : PTR, 2002, Volume: 16, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Anti-Inflammatory Agents; Antioxidants; Arachidonic Acid; Asteraceae; Carbon Tetrachloride; Edema; Free Radical Scavengers; Glucose Oxidase; Hydrogen Peroxide; Hydroxyl Radical; Inflammation; Lipid Peroxidation; Lipoxygenase; Methanol; Mice; Phytotherapy; Plant Extracts; Plant Roots; Pyrazoles; Superoxides; Vitamin E

2002