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phenformin and phenacetin

phenformin has been researched along with phenacetin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Park, BK1
Eichelbaum, M2
Venning, GR1

Reviews

1 review(s) available for phenformin and phenacetin

ArticleYear
[Genetic polymorphism of oxidative drug metabolism. Therapeutic and toxicologic implications].
    Der Internist, 1983, Volume: 24, Issue:3

    Topics: Adrenergic beta-Antagonists; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Hydroxylation; Mephenytoin; Oxidation-Reduction; Perhexiline; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenotype; Phenytoin; Polymorphism, Genetic; Receptors, Drug; Sparteine

1983

Other Studies

9 other study(ies) available for phenformin and phenacetin

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Metabolic basis of adverse drug reactions.
    Journal of the Royal College of Physicians of London, 1986, Volume: 20, Issue:3

    Topics: Acetaminophen; Acetylation; Adrenergic beta-Antagonists; Adult; Age Factors; Child; Debrisoquin; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Enzyme Inhibitors; Humans; Perhexiline; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenotype; Polymorphism, Genetic; Succinylcholine

1986
Identification of adverse reactions to new drugs. II--How were 18 important adverse reactions discovered and with what delays?
    British medical journal (Clinical research ed.), 1983, Jan-22, Volume: 286, Issue:6361

    Topics: Chloramphenicol; Clioquinol; Contraceptives, Oral; Diethylstilbestrol; Drug and Narcotic Control; Drug-Related Side Effects and Adverse Reactions; Halothane; Humans; Methysergide; Phenacetin; Phenformin; Practolol; Sympathomimetics; Time Factors; United Kingdom

1983
Polymorphic drug oxidation in humans.
    Federation proceedings, 1984, May-15, Volume: 43, Issue:8

    Topics: Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Debrisoquin; Humans; Mephenytoin; Microsomes, Liver; Oxidation-Reduction; Pharmaceutical Preparations; Phenacetin; Phenformin; Phenytoin; Polymorphism, Genetic; Sparteine; Tolbutamide

1984