phenelzine and hydralazine

phenelzine has been researched along with hydralazine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199017 (62.96)18.7374
1990's4 (14.81)18.2507
2000's1 (3.70)29.6817
2010's5 (18.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Drayer, DE; Reidenberg, MM1
Rumsby, PC; Shepherd, DM1
Gershbein, LL; Rao, KC1
Clark, DW1
Hovding, G1
Motulsky, AG1
Medzihradsky, F; Nandhasri, PS1
Dal Piaz, V; La Porta, E; Pinzauti, S1
Holmes, J; Sapeika, N; Zwarenstein, H1
Evans, DA4
Mattila, MJ1
Erwin, VG; Hellerman, L1
Callingham, BA; Lyles, GA1
Curran, NM; Lovering, EG; Matsui, F; Robertson, DL; Sears, RW1
Boucek, RJ; Simpson, CF1
Novak, RF; Runge-Morris, M; Wu, N1
Novak, RF; Runge-Morris, M1
Feng, Y; Novak, RF; Runge-Morris, M; Zangar, RC1
Acosta, G; Butler, B; Cao, P; Chen, Z; McCain, R; Ouyang, Z; Park, J; Shi, R; Tang, J; Vega-Alvarez, S; Zhang, W; Zheng, L1

Reviews

3 review(s) available for phenelzine and hydralazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Genetically determined variability in acetylation and oxidation. Therapeutic implications.
    Drugs, 1985, Volume: 29, Issue:4

    Topics: Acetylation; Anticonvulsants; Antidepressive Agents, Tricyclic; Debrisoquin; Disease; Drug Interactions; Genetic Variation; Humans; Hydralazine; Isoniazid; Oxidation-Reduction; Pharmaceutical Preparations; Phenelzine; Phenotype; Procainamide; Racial Groups; Sparteine; Sulfasalazine

1985
Genetic factors in drug therapy.
    The Scientific basis of medicine annual reviews, 1969

    Topics: Adolescent; Aged; Alcohol Oxidoreductases; Animals; Anticoagulants; Child; Female; Glaucoma; Humans; Hydralazine; Isoniazid; Liver; Male; Myocardial Infarction; Pharmaceutical Preparations; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenytoin; Polymorphism, Genetic; Polyneuropathies; Streptomycin; Sulfamethazine; Tuberculosis, Pulmonary

1969

Other Studies

24 other study(ies) available for phenelzine and hydralazine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Clinical consequences of polymorphic acetylation of basic drugs.
    Clinical pharmacology and therapeutics, 1977, Volume: 22, Issue:3

    Topics: Acetylation; Antibodies, Antinuclear; Biotransformation; Chemical and Drug Induced Liver Injury; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Pharmaceutical Preparations; Phenelzine; Phenotype; Polymorphism, Genetic; Procainamide; Sulfasalazine

1977
Effect of penicillamine, hydrallazine and phenelzine on the function of pyridoxal-5'-phosphate [proceedings].
    British journal of pharmacology, 1979, Volume: 67, Issue:3

    Topics: Animals; Hydralazine; Penicillamine; Phenelzine; Pyridoxal Phosphate; Rats

1979
Action of hydrazine drugs in tumor-free and 1,2-dimethylhydrazine-treated male rats.
    Oncology research, 1992, Volume: 4, Issue:3

    Topics: 1,2-Dimethylhydrazine; Adenocarcinoma; Administration, Oral; Animals; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Hydralazine; Injections, Subcutaneous; Isoniazid; Male; Phenelzine; Rats; Rats, Inbred Strains

1992
Occupational dermatitis from hydrazine hydrate used in boiler protection. Cross sensitization to apresoline, isoniazid and phenelzine.
    Acta dermato-venereologica, 1967, Volume: 47, Issue:5

    Topics: Adult; Dermatitis, Contact; Dermatitis, Occupational; Environmental Exposure; Humans; Hydralazine; Hydrazines; Isoniazid; Male; Phenelzine; Skin Tests

1967
Drugs and genes.
    Annals of internal medicine, 1969, Volume: 70, Issue:6

    Topics: Anemia, Hemolytic; Antipyrine; Dicumarol; Genes; Genetics, Medical; Humans; Hydralazine; Metabolism, Inborn Errors; Pharmaceutical Preparations; Pharmacogenetics; Pharmacology; Phenelzine; Phenylbutazone; Sulfamethazine

1969
Effects of some analgesics and antidepressants on the (Na + + K + )-adenosine triphosphatase from cortices of brain and kidney.
    Biochemical pharmacology, 1972, Aug-01, Volume: 21, Issue:15

    Topics: Adenosine Triphosphatases; Amitriptyline; Analgesics; Animals; Antidepressive Agents; Cattle; Cerebral Cortex; Chlorpromazine; Cyclazocine; Desipramine; Dose-Response Relationship, Drug; Hydralazine; Imipramine; In Vitro Techniques; Kidney; Kidney Cortex; Pentazocine; Phenazocine; Phenelzine; Potassium; Sodium; Tranylcypromine

1972
Chloramine-T as titrimetric reagent in potentiometric determination of isoniazid, phenelzine, and dihydralazine.
    Journal of pharmaceutical sciences, 1974, Volume: 63, Issue:9

    Topics: Chloramines; Chromatography, Thin Layer; Hydralazine; Indicators and Reagents; Isoniazid; Oxidation-Reduction; Phenelzine; Potentiometry; Temperature

1974
Inhibitory effect of some quinoline, phthalazine, and coumarin derivatives on glucose-6-phosphate dehydrogenase in vitro.
    Research communications in chemical pathology and pharmacology, 1973, Volume: 6, Issue:2

    Topics: Binding, Competitive; Chloroquine; Coumarins; Glucosephosphate Dehydrogenase; Heterocyclic Compounds; Hydralazine; Isoniazid; Novobiocin; Phenazines; Phenelzine; Phenylhydrazines; Probenecid; Pyridines; Quinacrine; Quinidine; Quinine; Quinolines; Sulfanilamides; Warfarin; Yeasts

1973
Phenelzine, hydralazine and diphenylhydantoin.
    Humangenetik, 1970, Volume: 9, Issue:3

    Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Biotransformation; Humans; Hydralazine; Mice; Phenelzine; Phenytoin; Polymorphism, Genetic; Rabbits; White People

1970
Pharmacogenetics.
    Transactions of the Medical Society of London, 1970, Volume: 86

    Topics: Aged; Cortisone; Enzyme Induction; Female; Glaucoma; Humans; Hydralazine; Intraocular Pressure; Isoniazid; Male; Nortriptyline; Pharmacogenetics; Phenacetin; Phenelzine; Phenotype; Phenylbutazone; Polymorphism, Genetic; Pregnancy; Sulfamethazine; Twins

1970
Mitochondrial monoamine oxidase. II. Action of various inhibitors for the bovine kidney enzyme. Catalytic mechanism.
    The Journal of biological chemistry, 1968, Oct-25, Volume: 243, Issue:20

    Topics: Amines; Animals; Carbon Isotopes; Cattle; Hydralazine; Kidney; Kinetics; Mitochondria; Models, Chemical; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pargyline; Phenelzine; Spectrophotometry; Stereoisomerism; Sulfhydryl Compounds; Tranylcypromine

1968
Hydralazine is an irreversible inhibitor of the semicarbazide-sensitive, clorgyline-resistant amine oxidase in rat aorta homogenates.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:2

    Topics: Amine Oxidase (Copper-Containing); Animals; Aorta; Blood Vessels; Clorgyline; Hydralazine; In Vitro Techniques; Kinetics; Male; Oxidoreductases Acting on CH-NH Group Donors; Phenelzine; Rats; Rats, Inbred Strains; Semicarbazides

1982
Hydrazine levels in formulations of hydralazine, isoniazid, and phenelzine over a 2-year period.
    Journal of pharmaceutical sciences, 1983, Volume: 72, Issue:8

    Topics: Drug Contamination; Drug Storage; Hydralazine; Hydrazines; Isoniazid; Phenelzine; Solutions; Tablets; Time Factors

1983
The B-aminopropionitrile-fed turkey: a model for detecting potential drug action on arterial tissue.
    Cardiovascular research, 1983, Volume: 17, Issue:1

    Topics: Aminopropionitrile; Animals; Aorta, Abdominal; Aortic Aneurysm; Aortic Diseases; Disease Models, Animal; Hemodynamics; Hydralazine; Male; Phenelzine; Practolol; Propranolol; Reserpine; Sotalol; Tensile Strength; Turkeys

1983
Hydrazine-mediated DNA damage: role of hemoprotein, electron transport, and organic free radicals.
    Toxicology and applied pharmacology, 1994, Volume: 125, Issue:1

    Topics: DNA Damage; DNA, Superhelical; Electron Transport; Erythrocytes; Free Radicals; Hemoglobins; Humans; Hydralazine; Hydrazines; Monomethylhydrazine; Phenelzine; Phenylhydrazines

1994
Effects of phenelzine and hydralazine on hydrogen peroxide production and proteolysis in human red blood cells.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Blood Proteins; Blotting, Western; Calpain; Cells, Cultured; Chromatography, High Pressure Liquid; Egtazic Acid; Erythrocytes; Free Radical Scavengers; Humans; Hydralazine; Hydrogen Peroxide; Phenelzine; Reactive Oxygen Species; Stimulation, Chemical

1993
Effects of hydrazine, phenelzine, and hydralazine treatment on rat hepatic and renal drug-metabolizing enzyme expression.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:7

    Topics: Animals; Blotting, Northern; Cytochrome P-450 CYP2E1; Glutathione Transferase; Hydralazine; Hydrazines; Kidney; Liver; Male; Phenelzine; Rats; Rats, Sprague-Dawley; RNA, Messenger

1996
ENZYMES AND DRUG SENSITIVITY. ACETYLATION POLYMORPHISMS.
    Proceedings of the Royal Society of Medicine, 1964, Volume: 57

    Topics: Acetylation; Aminosalicylic Acid; Aminosalicylic Acids; Biomedical Research; Genetics, Medical; Hydralazine; Isoniazid; Liver; Metabolism; Monoamine Oxidase Inhibitors; Phenelzine; Toxicology

1964
CONJOINT CLINIC ON DRUGS AND GENES.
    Journal of chronic diseases, 1965, Volume: 18

    Topics: Acetates; Aminosalicylic Acid; Aminosalicylic Acids; Coenzyme A; Diabetes Mellitus; Genetics, Medical; Glucosephosphate Dehydrogenase Deficiency; Glucosephosphates; Hydralazine; Insulin; Isoniazid; Kidney; Liver; Metabolism; Neuritis; Pharmacology; Phenelzine; Sulfamethazine; Toxicology

1965
Mitigation of sensory and motor deficits by acrolein scavenger phenelzine in a rat model of spinal cord contusive injury.
    Journal of neurochemistry, 2016, Volume: 138, Issue:2

    Topics: Animals; Behavior, Animal; Contusions; Disease Models, Animal; Hydralazine; Hyperalgesia; Male; Neuralgia; Phenelzine; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries

2016