Page last updated: 2024-08-17

phencyclidine and memantine

phencyclidine has been researched along with memantine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (35.29)18.2507
2000's2 (11.76)29.6817
2010's7 (41.18)24.3611
2020's2 (11.76)2.80

Authors

AuthorsStudies
Hecht, P; Kornhuber, J; Koutsilieri, E; Kroemer, RT; Liedl, KR; Riederer, P1
Bergander, K; Fabian, J; Köhler, J; Schepmann, D; Wünsch, B1
Berger, ML; Rebernik, P1
Dos Santos, DJVA; Espadinha, M; Gonçalves, L; Herrera-Arozamena, C; Lopes, RMRM; Molins, E; Ríos, CL; Rodríguez-Franco, MI; Santos, MMM; Viejo, L1
Egunlusi, AO; Ekpo, OE; Joubert, J; Malan, SF; Omoruyi, SI; Palchykov, VA1
Gruner, R; Lodge, D; Millar, J; Parsons, CG; Rozental, J1
Colombo, G; Grant, J; Grant, KA; Rogawski, MA1
Hashimoto, K; Minabe, Y; Narita, N; Tamura, A; Tomitaka, SI1
Deutsch, SI; Mastropaolo, J; Riggs, RL; Rosse, RB1
Balster, RL; Jones, HE; Nicholson, KL1
Mintzer, JE1
Kato, T1
Circelli, C; Dix, SL; Fletcher, AC; Talpos, JC; Tricklebank, MD1
Chaki, S; Hiyoshi, T; Kambe, D; Karasawa, J1
Adel, D; Alonso, M; Belhadj-Tahar, H; Fonta, C; Fontan, C; Payoux, P; Pestourie, C; Salabert, AS; Tafani, M1
Daniliuc, C; Ehrhardt, C; Frehland, B; Lehmkuhl, K; Schepmann, D; Torres-Gómez, H; Wünsch, B1
Culley, G; Dósa, Z; Fröjd, V; Hanse, E; Radi, S; Riebe, I; Seth, H; Strand, K1

Reviews

2 review(s) available for phencyclidine and memantine

ArticleYear
The search for better noncholinergic treatment options for Alzheimer's disease.
    The Journal of clinical psychiatry, 2003, Volume: 64 Suppl 9

    Topics: Alzheimer Disease; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Humans; Memantine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Selective Serotonin Reuptake Inhibitors

2003
[Role of magnesium ions on the regulation of NMDA receptor--a pharmacopathology of memantine].
    Clinical calcium, 2004, Volume: 14, Issue:8

    Topics: Alzheimer Disease; Binding Sites; Brain Ischemia; Dizocilpine Maleate; Humans; Magnesium; Memantine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Schizophrenia

2004

Other Studies

15 other study(ies) available for phencyclidine and memantine

ArticleYear
Quantitative analysis of the structural requirements for blockade of the N-methyl-D-aspartate receptor at the phencyclidine binding site.
    Journal of medicinal chemistry, 1998, Jan-29, Volume: 41, Issue:3

    Topics: Binding Sites; Excitatory Amino Acid Antagonists; Humans; Molecular Structure; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1998
Enantiomerically pure 1,3-dioxanes as highly selective NMDA and σ₁ receptor ligands.
    Journal of medicinal chemistry, 2012, Oct-25, Volume: 55, Issue:20

    Topics: Animals; Benzylamines; Binding Sites; Binding, Competitive; Cerebral Cortex; Dioxanes; Ethylamines; Guinea Pigs; Ligands; Phencyclidine; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Stereoisomerism; Swine

2012
Differential influence of 7 cations on 16 non-competitive NMDA receptor blockers.
    Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

    Topics: Animals; Brain; Cations; Diamines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Molecular Structure; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2015
Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders.
    European journal of medicinal chemistry, 2020, May-15, Volume: 194

    Topics: Blood-Brain Barrier; Cells, Cultured; Dose-Response Relationship, Drug; HEK293 Cells; Hep G2 Cells; Humans; Lactams; Molecular Docking Simulation; Molecular Structure; Nervous System Diseases; Neuroprotective Agents; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2020
Open and rearranged norbornane derived polycyclic cage molecules as potential neuroprotective agents through attenuation of MPP
    European journal of medicinal chemistry, 2020, Oct-15, Volume: 204

    Topics: 1-Methyl-4-phenylpyridinium; Calcium; Cell Line, Tumor; Humans; Ion Transport; Molecular Docking Simulation; Neuroblastoma; Neuroprotective Agents; Norbornanes; Polycyclic Compounds; Receptors, N-Methyl-D-Aspartate; Spectrum Analysis; Structure-Activity Relationship

2020
Patch clamp studies on the kinetics and selectivity of N-methyl-D-aspartate receptor antagonism by memantine (1-amino-3,5-dimethyladamantan).
    Neuropharmacology, 1993, Volume: 32, Issue:12

    Topics: Animals; Cells, Cultured; Dextrorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Embryo, Mammalian; gamma-Aminobutyric Acid; Glycine; Hippocampus; Ketamine; Kinetics; Magnesium; Memantine; Membrane Potentials; N-Methylaspartate; Neurons; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Superior Colliculi

1993
Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists.
    Neuropharmacology, 1996, Volume: 35, Issue:12

    Topics: Acetamides; Analysis of Variance; Anesthetics, Dissociative; Animals; Conditioning, Operant; Dextromethorphan; Dioxolanes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Memantine; Phencyclidine; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate

1996
Regionally different effects of scopolamine on NMDA antagonist-induced heat shock protein HSP70.
    Brain research, 1997, Jul-25, Volume: 763, Issue:2

    Topics: Animals; Antibody Specificity; Cerebral Cortex; Excitatory Amino Acid Antagonists; HSP70 Heat-Shock Proteins; Male; Memantine; Muscarinic Antagonists; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Scopolamine

1997
The antiseizure efficacies of MK-801, phencyclidine, ketamine, and memantine are altered selectively by stress.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:3

    Topics: Animals; Anticonvulsants; Cold Temperature; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Memantine; Mice; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Stress, Psychological

1997
Evaluation of the reinforcing and discriminative stimulus properties of the low-affinity N-methyl-D-aspartate channel blocker memantine.
    Behavioural pharmacology, 1998, Volume: 9, Issue:3

    Topics: Amantadine; Animals; Discrimination, Psychological; Dopamine Agents; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Female; Macaca mulatta; Male; Memantine; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Self Administration

1998
The pharmacological sensitivity of a touchscreen-based visual discrimination task in the rat using simple and perceptually challenging stimuli.
    Psychopharmacology, 2012, Volume: 221, Issue:3

    Topics: Animals; Behavior, Animal; Cognition; Computers; Conditioning, Operant; Dextroamphetamine; Discrimination Learning; Dizocilpine Maleate; Male; Memantine; Phencyclidine; Psychotropic Drugs; Rats; Scopolamine

2012
Differential effects of NMDA receptor antagonists at lower and higher doses on basal gamma band oscillation power in rat cortical electroencephalograms.
    Neuropharmacology, 2014, Volume: 85

    Topics: Amphetamines; Animals; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrodes, Implanted; Electroencephalography; Excitatory Amino Acid Antagonists; Gamma Rhythm; Ketamine; Male; Memantine; Methamphetamine; Phencyclidine; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

2014
Radiolabeling of [18F]-fluoroethylnormemantine and initial in vivo evaluation of this innovative PET tracer for imaging the PCP sites of NMDA receptors.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:8

    Topics: Animals; Autoradiography; Brain; Fluorine Radioisotopes; Isotope Labeling; Kinetics; Male; Memantine; Metabolic Clearance Rate; Phencyclidine; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tissue Distribution

2015
Stereoselective synthesis and pharmacological evaluation of [4.3.3]propellan-8-amines as analogs of adamantanamines.
    Bioorganic & medicinal chemistry, 2015, Aug-01, Volume: 23, Issue:15

    Topics: Amantadine; Animals; Antiviral Agents; Binding Sites; Cell Line; Chemistry Techniques, Synthetic; Crystallography, X-Ray; Dogs; Drug Evaluation, Preclinical; Humans; Influenza A virus; Madin Darby Canine Kidney Cells; Memantine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Static Electricity; Stereoisomerism

2015
Tonically active NMDA receptors--a signalling mechanism critical for interneuronal excitability in the CA1 stratum radiatum.
    The European journal of neuroscience, 2016, Volume: 43, Issue:2

    Topics: Animals; CA1 Region, Hippocampal; Cerebrospinal Fluid; Culture Media; Excitatory Postsynaptic Potentials; Female; GABAergic Neurons; Humans; Inhibitory Postsynaptic Potentials; Interneurons; Male; Memantine; Neural Inhibition; Phencyclidine; Pyramidal Cells; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Potentials

2016