Page last updated: 2024-08-17

phencyclidine and dextromethorphan

phencyclidine has been researched along with dextromethorphan in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19903 (9.09)18.7374
1990's16 (48.48)18.2507
2000's10 (30.30)29.6817
2010's2 (6.06)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Hecht, P; Kornhuber, J; Koutsilieri, E; Kroemer, RT; Liedl, KR; Riederer, P1
Almonte, A; Balster, R; Barber, J; Dravid, SM; Erreger, K; French, A; Le, P; Lyuboslavsky, P; Mosely, C; Murray, E; Murray, TF; Nicholson, K; Traynelis, SF; Yuan, H1
Berger, ML; Hammerschmidt, F; Rebernik, P; Schweifer, A1
Berger, ML; Rebernik, P1
Franklin, PH; Murray, TF; Roth, JE; Zhang, G1
Lemaire, S; Rogers, C1
Bao, WL; Sun, FY; Zhang, AZ; Zheng, FC1
Jaffe, JH; Sharpe, LG; Székely, JI2
Loo, PS; Sills, MA1
Domino, EF; Krutak-Krol, H; Lal, J1
Leid, ME; Murray, TF1
Diana, G; Pezzola, A; Popoli, P; Sagratella, S; Scotti de Carolis, A1
Holtzman, SG1
De Sarro, A; De Sarro, GB1
Shi, GG; Xu, SF1
Kamei, H; Kameyama, T; Nabeshima, T1
Larsen, H; Monaghan, DT1
Colombo, G; Grant, J; Grant, KA; Rogawski, MA1
Camarasa, J; Camins, A; Canudas, AM; Escubedo, E; Pallas, M; Pubill, D; Sureda, FX1
Liu, BJ; Shi, GG; Wei, DS; Xu, SF1
Balster, RL; Hayes, BA; Nicholson, KL1
Schier, J1
Aoki, K; Narita, M; Nomura, M; Suzuki, T; Yoshizawa, K1
Budai, B; Iskandar, H1
Gasior, M; Geter-Douglass, B; Newman, AH; Tortella, FC; Witkin, JM; Zapata, A1
Sun, W; Wessinger, WD1
Jozwiak, K; Moaddel, R; Wainer, IW; Whittington, K1
García-Algar, O; Marchei, E; Martín, I; Pellegrini, M; Pichini, S; Vall, O1
Li, M; McMillan, DE; Wessinger, WD1
Mullins, ME; Rengarajan, A1
Bates, MLS; Trujillo, KA1
Daniels, RN; McClure, EW1

Reviews

2 review(s) available for phencyclidine and dextromethorphan

ArticleYear
Use and abuse of dissociative and psychedelic drugs in adolescence.
    Pharmacology, biochemistry, and behavior, 2021, Volume: 203

    Topics: Adolescent; Adult; Age Factors; Animals; Dextromethorphan; Female; Hallucinogens; Humans; Ketamine; Lysergic Acid Diethylamide; Male; N-Methyl-3,4-methylenedioxyamphetamine; Phencyclidine; Psilocybin; Risk-Taking; Substance-Related Disorders

2021
Classics in Chemical Neuroscience: Dextromethorphan (DXM).
    ACS chemical neuroscience, 2023, 06-21, Volume: 14, Issue:12

    Topics: Antitussive Agents; Dextromethorphan; Hallucinogens; Humans; Ketamine; Phencyclidine; Receptors, N-Methyl-D-Aspartate

2023

Other Studies

31 other study(ies) available for phencyclidine and dextromethorphan

ArticleYear
Quantitative analysis of the structural requirements for blockade of the N-methyl-D-aspartate receptor at the phencyclidine binding site.
    Journal of medicinal chemistry, 1998, Jan-29, Volume: 41, Issue:3

    Topics: Binding Sites; Excitatory Amino Acid Antagonists; Humans; Molecular Structure; Phencyclidine; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

1998
Subunit-specific mechanisms and proton sensitivity of NMDA receptor channel block.
    The Journal of physiology, 2007, May-15, Volume: 581, Issue:Pt 1

    Topics: Animals; Cell Line; Dizocilpine Maleate; Electrophysiology; Excitatory Amino Acid Antagonists; Humans; Hydrogen-Ion Concentration; Ion Channel Gating; Ion Channels; Male; Mice; Mice, Inbred C57BL; Patch-Clamp Techniques; Protons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Stereoisomerism; Xenopus laevis

2007
NMDA receptor affinities of 1,2-diphenylethylamine and 1-(1,2-diphenylethyl)piperidine enantiomers and of related compounds.
    Bioorganic & medicinal chemistry, 2009, May-01, Volume: 17, Issue:9

    Topics: Animals; Brain; Dizocilpine Maleate; Kinetics; Membranes; Phenethylamines; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Stereoisomerism

2009
Differential influence of 7 cations on 16 non-competitive NMDA receptor blockers.
    Bioorganic & medicinal chemistry letters, 2015, Oct-01, Volume: 25, Issue:19

    Topics: Animals; Brain; Cations; Diamines; Dizocilpine Maleate; Dose-Response Relationship, Drug; Molecular Structure; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship

2015
Dextrorotatory opioids and phencyclidine exert anticonvulsant action in prepiriform cortex.
    European journal of pharmacology, 1992, May-14, Volume: 215, Issue:2-3

    Topics: Animals; Anticonvulsants; Bicuculline; Cerebral Cortex; Dextromethorphan; Dextrorphan; Dizocilpine Maleate; Male; Microinjections; Narcotics; Pentazocine; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Stereoisomerism

1992
Characterization of [3H]desmethylimipramine binding in bovine adrenal medulla: interactions with sigma- and (or) phencyclidine-receptor ligands.
    Canadian journal of physiology and pharmacology, 1992, Volume: 70, Issue:11

    Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Desipramine; Dextromethorphan; Dizocilpine Maleate; Phenazocine; Phencyclidine; Piperidines; Potassium Chloride; Receptors, Opioid, delta; Receptors, Phencyclidine; Tranquilizing Agents

1992
[Antagonistic effects of dextromethorphan on vasoconstriction of phencyclidine in vitro].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:3

    Topics: Animals; Biological Assay; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; Norepinephrine; Phencyclidine; Rabbits; Vasoconstriction

1991
Induction of phencyclidine-like behavior in rats by dextrorphan but not dextromethorphan.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:2

    Topics: Animals; Ataxia; Behavior, Animal; Dextromethorphan; Dextrorphan; Dose-Response Relationship, Drug; Male; Motor Activity; Phencyclidine; Rats; Rats, Inbred Strains; Stereotyped Behavior

1991
Dextromethorphan inhibits but dextrorphan potentiates behavior induced by PCP and ketamine in rats.
    NIDA research monograph, 1990, Volume: 105

    Topics: Animals; Behavior, Animal; Dextromethorphan; Dextrorphan; Ketamine; Motor Activity; Phencyclidine; Rats

1990
Tricyclic antidepressants and dextromethorphan bind with higher affinity to the phencyclidine receptor in the absence of magnesium and L-glutamate.
    Molecular pharmacology, 1989, Volume: 36, Issue:1

    Topics: Animals; Antidepressive Agents, Tricyclic; Dextromethorphan; Glutamates; Glutamic Acid; In Vitro Techniques; Levorphanol; Magnesium; Male; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine

1989
Comparative antitussive effects of dextrorphan, dextromethorphan and phencyclidine.
    Arzneimittel-Forschung, 1986, Volume: 36, Issue:7

    Topics: Animals; Antitussive Agents; Cats; Cough; Decerebrate State; Dextromethorphan; Dextrorphan; Female; Levorphanol; Morphinans; Phencyclidine

1986
Interaction of dextrorotatory opioids with phencyclidine recognition sites in rat brain membranes.
    Life sciences, 1984, May-14, Volume: 34, Issue:20

    Topics: Animals; Brain; Dextromethorphan; Dextrorphan; In Vitro Techniques; Narcotics; Phencyclidine; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Stereoisomerism; Tritium

1984
Non-opioid antitussives potentiate some behavioural and EEG effects of N-methyl-D-aspartate channel blockers.
    Life sciences, 1993, Volume: 52, Issue:19

    Topics: Animals; Antitussive Agents; Behavior, Animal; Cyclopentanes; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Synergism; Electroencephalography; Ion Channels; Male; Mice; Phencyclidine; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate

1993
Discriminative stimulus effects of dextromethorphan in the rat.
    Psychopharmacology, 1994, Volume: 116, Issue:3

    Topics: Animals; Antitussive Agents; Dextromethorphan; Discrimination, Psychological; Generalization, Stimulus; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Receptors, Phencyclidine; Receptors, sigma

1994
Anticonvulsant properties of non-competitive antagonists of the N-methyl-D-aspartate receptor in genetically epilepsy-prone rats: comparison with CPPene.
    Neuropharmacology, 1993, Volume: 32, Issue:1

    Topics: Acoustic Stimulation; Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Dextromethorphan; Dizocilpine Maleate; Epilepsy; Injections, Intraperitoneal; Ketamine; Male; Movement; Phencyclidine; Piperazines; Piperidines; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1993
Effect of phencyclidine on contraction of porcine coronary vessel strips.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1993, Volume: 14, Issue:3

    Topics: Animals; Biological Assay; Coronary Vessels; Dextromethorphan; Dizocilpine Maleate; Haloperidol; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardial Contraction; Phenazocine; Phencyclidine; Receptors, Phencyclidine; Receptors, sigma; Swine

1993
(+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress through the activation of phenytoin-regulated sigma 1 sites.
    European journal of pharmacology, 1996, Mar-28, Volume: 299, Issue:1-3

    Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Phenazocine; Phencyclidine; Phenytoin; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Stress, Physiological

1996
NR1 and NR2 subunit contributions to N-methyl-D-aspartate receptor channel blocker pharmacology.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 280, Issue:2

    Topics: Acetamides; Alternative Splicing; Animals; Dextromethorphan; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Glycine; Illicit Drugs; Ion Channels; Kinetics; Membrane Potentials; Oocytes; Phencyclidine; Protein Biosynthesis; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Transcription, Genetic; Xenopus laevis

1997
Dizocilpine-like discriminative stimulus effects of low-affinity uncompetitive NMDA antagonists.
    Neuropharmacology, 1996, Volume: 35, Issue:12

    Topics: Acetamides; Analysis of Variance; Anesthetics, Dissociative; Animals; Conditioning, Operant; Dextromethorphan; Dioxolanes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Male; Memantine; Phencyclidine; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate

1996
Effect of PCP and sigma ligands on both noradrenaline- and electrically-induced contractions and on [3H]-noradrenaline uptake in rat vas deferens.
    Journal of autonomic pharmacology, 1998, Volume: 18, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Dextromethorphan; Dizocilpine Maleate; Dopamine Agonists; Electric Stimulation; Excitatory Amino Acid Antagonists; Ligands; Male; Muscle Contraction; Neuroprotective Agents; Norepinephrine; Phencyclidine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Phencyclidine; Receptors, sigma; Tritium; Vas Deferens

1998
Effect of phencyclidine on dog coronary artery.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:3

    Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Vessels; Dextromethorphan; Dogs; Excitatory Amino Acid Antagonists; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phencyclidine; Receptors, Phencyclidine

1996
Evaluation of the reinforcing properties and phencyclidine-like discriminative stimulus effects of dextromethorphan and dextrorphan in rats and rhesus monkeys.
    Psychopharmacology, 1999, Sep-01, Volume: 146, Issue:1

    Topics: Animals; Antitussive Agents; Dextromethorphan; Discrimination Learning; Dose-Response Relationship, Drug; Macaca mulatta; Male; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Reinforcement, Psychology; Self Administration

1999
Avoid unfavorable consequences: dextromethorpan can bring about a false-positive phencyclidine urine drug screen.
    The Journal of emergency medicine, 2000, Volume: 18, Issue:3

    Topics: Antitussive Agents; Dextromethorphan; Diagnosis, Differential; Drug Evaluation, Preclinical; Dystonia; Emergency Service, Hospital; False Positive Reactions; Female; Humans; Infant; Phencyclidine; Poisoning; Risk Assessment; Unconsciousness; Urine

2000
Role of the NMDA receptor subunit in the expression of the discriminative stimulus effect induced by ketamine.
    European journal of pharmacology, 2001, Jun-29, Volume: 423, Issue:1

    Topics: Animals; Dextromethorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Guanidines; Ketamine; Ligands; Male; Phencyclidine; Piperazines; Piperidines; Protein Subunits; Rats; Rats, Inbred F344; Receptors, N-Methyl-D-Aspartate; Receptors, sigma

2001
Dextromethorphan can produce false positive phencyclidine testing with HPLC.
    The American journal of emergency medicine, 2002, Volume: 20, Issue:1

    Topics: Adolescent; Antitussive Agents; Chromatography, High Pressure Liquid; Dextromethorphan; Drug Interactions; False Positive Reactions; Hallucinogens; Humans; Male; Phencyclidine; Phencyclidine Abuse; Substance Abuse Detection

2002
Attenuation of the stimulant and convulsant effects of cocaine by 17-substituted-3-hydroxy and 3-alkoxy derivatives of dextromethorphan.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:2

    Topics: Animals; Anticonvulsants; Behavior, Animal; Central Nervous System Stimulants; Cocaine; Convulsants; Dextromethorphan; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Phencyclidine; Receptors, sigma

2003
Characterization of the non-competitive antagonist binding site of the NMDA receptor in dark Agouti rats.
    Life sciences, 2004, Aug-06, Volume: 75, Issue:12

    Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dioxolanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; N-Methylaspartate; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Scintillation Counting; Tritium

2004
Conformational mobility of immobilized alpha3beta2, alpha3beta4, alpha4beta2, and alpha4beta4 nicotinic acetylcholine receptors.
    Analytical chemistry, 2005, Feb-01, Volume: 77, Issue:3

    Topics: Alkaloids; Azocines; Binding, Competitive; Biomarkers; Bridged Bicyclo Compounds, Heterocyclic; Cell Line; Chromatography, Affinity; Chromatography, Liquid; Dextromethorphan; Mecamylamine; Membranes, Artificial; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phencyclidine; Protein Conformation; Pyridines; Quinolizines; Receptors, Nicotinic

2005
Are false-positive phencyclidine immunoassay instant-view multi-test results caused by overdose concentrations of Ibuprofen, metamizol, and dextromethorphan?
    Therapeutic drug monitoring, 2007, Volume: 29, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Child, Preschool; Dextromethorphan; Diagnosis, Differential; Dipyrone; Drug Overdose; False Positive Reactions; Female; Humans; Ibuprofen; Immunoassay; Infant, Newborn; Male; Phencyclidine; Seizures

2007
Effects of drugs and drug combinations in pigeons trained to discriminate among pentobarbital, dizocilpine, a combination of these drugs, and saline.
    Journal of the experimental analysis of behavior, 2009, Volume: 92, Issue:3

    Topics: Animals; Central Nervous System Depressants; Central Nervous System Stimulants; Choice Behavior; Dextromethorphan; Dextrorphan; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Ethanol; Excitatory Amino Acid Antagonists; GABA Modulators; Male; Pentobarbital; Phencyclidine; Reaction Time; Receptors, GABA-A

2009
How often do false-positive phencyclidine urine screens occur with use of common medications?
    Clinical toxicology (Philadelphia, Pa.), 2013, Volume: 51, Issue:6

    Topics: Alprazolam; Carbazoles; Carvedilol; Clonazepam; Dextromethorphan; Diphenhydramine; Drug Interactions; False Positive Reactions; Gas Chromatography-Mass Spectrometry; Humans; Phencyclidine; Propanolamines; Retrospective Studies; Substance-Related Disorders; Tramadol

2013