phenazocine has been researched along with dizocilpine maleate in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (26.00) | 18.7374 |
| 1990's | 29 (58.00) | 18.2507 |
| 2000's | 8 (16.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maneckjee, R; Minna, JD | 1 |
| Lemaire, S; Rogers, C | 1 |
| Hudzik, TJ | 1 |
| Beaton, JA; Monaghan, DT; Stemsrud, K | 1 |
| Hudzik, TJ; Slifer, BL | 1 |
| McCann, DJ; Su, TP | 1 |
| Feuerstein, G; Gagnon, RC; Gu, JL; Lysko, PG; Yue, TL | 1 |
| Mitchell, KN; Tam, SW | 1 |
| Boyce, S; Cook, G; Iversen, SD; Rupniak, NM; Steventon, MJ | 1 |
| deCosta, BR; Hardwick, WC; McMillan, DE; Rice, KC | 1 |
| Carter, AJ; Müller, RE | 1 |
| Brent, PJ | 1 |
| Duckles, SP; Massamiri, T | 1 |
| Kesingland, AC; Singh, L; Tricklebank, MD; Wong, EH | 1 |
| Bauerle, LM; DeNoble, VJ; Jones, KW | 1 |
| Beinfeld, MC; Brog, JS | 1 |
| DeLander, GE; Wahl, JJ | 1 |
| Ahier, RG; Middlemiss, DN; Price, GW; Singh, L; Tricklebank, MD; Wong, EH | 1 |
| France, CP; Snyder, AM; Woods, JH | 1 |
| Wann, KT; Wardley-Smith, B | 1 |
| Iversen, SD; Oles, RJ; Preston, C; Singh, L; Tricklebank, MD | 1 |
| Balster, RL; Willetts, J | 1 |
| Gussio, RP; Marquis, KL; Moreton, JE; Paquette, NC | 1 |
| Jackson, A; Sanger, DJ | 2 |
| Foster, AC; Gill, R; Iversen, LL; Kemp, JA; Wong, EH; Woodruff, GN | 1 |
| Knight, AR; Wong, EH; Woodruff, GN | 1 |
| Beart, PM; Manallack, DT | 1 |
| Iversen, LL; Kemp, JA; Knight, AR; Priestley, T; Wong, EH; Woodruff, GN | 1 |
| Ohno, M; Watanabe, S | 1 |
| Bao, WL; Sun, FY; Zhang, AZ; Zhen, FC | 1 |
| Hasegawa, T; Hiramatsu, M; Itoh, J; Kameyama, T; Maurice, T; Nabeshima, T | 1 |
| Lysko, PG; Sauermelch, CF; Willette, RN | 1 |
| McCann, DJ; Su, TP; Weissman, AD | 1 |
| Brent, PJ; Chahl, LA | 1 |
| Shi, GG; Xu, SF | 1 |
| Masaki, H; Mishina, M; Mori, H; Shimoji, K; Yamakura, T | 1 |
| Kamei, H; Kameyama, T; Nabeshima, T | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Noda, Y | 1 |
| Nabeshima, T; Yamada, K; Zou, LB | 1 |
| Ahmed, MS; Enna, SJ; Mather, A | 1 |
| Maurice, T; Phan, VL; Privat, A; Su, TP | 1 |
| Furukawa, H; Ichihara, K; Kamei, H; Mamiya, T; Nabeshima, T; Nagai, T; Noda, A; Noda, Y; Sugiura, S | 1 |
| Maurice, T; Phan, VL; Privat, A | 1 |
| Guillemain, I; Maurice, T; Phan, VL; Urani, A | 1 |
| Dikranian, K; Farber, NB; Heinkel, C; Jiang, XP; Kim, SH | 1 |
| Horikomi, K; Karasawa, J; Sagi, N; Sora, I; Yamamoto, H; Yamamoto, T | 1 |
| Akaike, A; Hashino, A; Kaneko, S; Katsuki, H; Kume, T; Minami, M; Nishikawa, H; Satoh, M; Taguchi, R | 1 |
| Sun, W; Wessinger, WD | 1 |
| Tanabe, M | 1 |
1 review(s) available for phenazocine and dizocilpine maleate
| Article | Year |
|---|---|
The interaction between MK-801 and receptors for N-methyl-D-aspartate: functional consequences.
Topics: Anesthetics; Animals; Autoradiography; Cerebral Cortex; Choline O-Acetyltransferase; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electrophysiology; Phenazocine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, sigma | 1987 |
49 other study(ies) available for phenazocine and dizocilpine maleate
| Article | Year |
|---|---|
Biologically active MK-801 and SKF-10,047 binding sites distinct from those in rat brain are expressed on human lung cancer cells.
Topics: Animals; Binding, Competitive; Brain; Dizocilpine Maleate; Humans; Lung Neoplasms; Phenazocine; Radioligand Assay; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Stereoisomerism; Tumor Cells, Cultured | 1992 |
Characterization of [3H]desmethylimipramine binding in bovine adrenal medulla: interactions with sigma- and (or) phencyclidine-receptor ligands.
Topics: Adrenal Medulla; Animals; Binding Sites; Cattle; Desipramine; Dextromethorphan; Dizocilpine Maleate; Phenazocine; Phencyclidine; Piperidines; Potassium Chloride; Receptors, Opioid, delta; Receptors, Phencyclidine; Tranquilizing Agents | 1992 |
Sigma ligand-induced emesis in the pigeon.
Topics: Animals; Apomorphine; Columbidae; Dextromethorphan; Dizocilpine Maleate; Dopamine Agents; Guanidines; Haloperidol; Male; Pentobarbital; Phenazocine; Piperidines; Propranolol; Psychotropic Drugs; Pyrimidines; Receptors, Opioid; Receptors, sigma; Vomiting | 1992 |
Identification of a novel N-methyl-D-aspartate receptor population in the rat medial thalamus.
Topics: Animals; Autoradiography; Cerebellum; Dizocilpine Maleate; Glutamates; Phenazocine; Piperazines; Prosencephalon; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Thalamus | 1992 |
Interaction of sigma and PCP-like drugs on operant behaviors in the rat.
Topics: Animals; Conditioning, Operant; Dextroamphetamine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; Pentazocine; Phenazocine; Phencyclidine; Psychotropic Drugs; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Reinforcement Schedule | 1992 |
Tris inhibits (+)-[3H]SKF-10,047 binding to sigma receptors.
Topics: Animals; Dizocilpine Maleate; Haloperidol; Liver; Male; Phenazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stereoisomerism; Tritium; Tromethamine | 1992 |
Neuroprotective effects of SKF 10,047 in cultured rat cerebellar neurons and in gerbil global brain ischemia.
Topics: Animals; Body Temperature; Brain Ischemia; Cells, Cultured; Cerebellum; Cyclazocine; Dizocilpine Maleate; Gerbillinae; Pentazocine; Phenazocine; Rats; Rats, Inbred Strains; Reference Values; Stereoisomerism | 1992 |
Neuropeptide Y and peptide YY do not bind to brain sigma and phencyclidine binding sites.
Topics: Animals; Brain; Dizocilpine Maleate; Guinea Pigs; In Vitro Techniques; Neuropeptide Y; Peptide YY; Peptides; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Temperature | 1991 |
Psychomotor activity and cognitive disruption attributable to NMDA, but not sigma, interactions in primates.
Topics: Animals; Ataxia; Cognition; Dizocilpine Maleate; Macaca mulatta; Male; Pentazocine; Phenazocine; Phencyclidine; Psychomotor Performance; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid; Receptors, sigma; Saimiri; Space Perception | 1991 |
Effects of drugs that bind to PCP and sigma receptors on punished responding.
Topics: Animals; Buspirone; Dizocilpine Maleate; Haloperidol; Learning; Male; Pentobarbital; Phenazocine; Phencyclidine; Punishment; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1991 |
Activation of excitatory amino acid receptors cannot alone account for anoxia-induced impairment of protein synthesis in rat hippocampal slices.
Topics: Animals; Aspartic Acid; Carbon Radioisotopes; Dizocilpine Maleate; Glutamates; Glutamic Acid; Hippocampus; Hypoxia; Kainic Acid; Lysine; Male; N-Methylaspartate; Nerve Tissue Proteins; Phenazocine; Phencyclidine; Quisqualic Acid; Rats; Receptors, Amino Acid; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate | 1991 |
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Guanidines; Guinea Pigs; Haloperidol; Ketamine; Male; Motor Activity; N-Methylaspartate; Pentazocine; Phenazocine; Phencyclidine; Quinpirole; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride | 1991 |
Interactions of sigma and phencyclidine receptor ligands with the norepinephrine uptake carrier in both rat brain and rat tail artery.
Topics: Animals; Biological Transport; Brain; Desipramine; Dizocilpine Maleate; Male; Norepinephrine; Phenazocine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma; Tail; Vasoconstriction | 1991 |
Evidence against an involvement of the haloperidol-sensitive sigma recognition site in the discriminative stimulus properties of (+)-N-allylnormetazocine ((+)-SKF 10,047).
Topics: Animals; Aspartic Acid; Binding, Competitive; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Guanidines; Haloperidol; Male; Mice; N-Methylaspartate; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1990 |
Differential effects of sigma and phencyclidine receptor ligands on learning.
Topics: Animals; Avoidance Learning; Dibenzocycloheptenes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Ligands; Male; Memory; Pentazocine; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Phencyclidine; Retention, Psychology | 1990 |
Inhibition of carbachol-induced inositol phosphate accumulation by phencyclidine, phencyclidine-like ligands and sigma agonists involves blockade of the muscarinic cholinergic receptor: a novel dioxadrol-preferring interaction.
Topics: Animals; Brain; Carbachol; Culture Techniques; Dibenzocycloheptenes; Dioxolanes; Dizocilpine Maleate; Inositol Phosphates; Male; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sigma Factor; Transcription Factors | 1990 |
In vivo characterization of phencyclidine/sigma agonist-mediated inhibition of nociception.
Topics: Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Binding, Competitive; Dibenzocycloheptenes; Dizocilpine Maleate; Male; Mice; N-Methylaspartate; Nociceptors; Phenazocine; Phencyclidine; Receptors, Opioid; Receptors, Opioid, delta; Substance P | 1989 |
In vivo labelling of the NMDA receptor channel complex by [3H]MK-801.
Topics: Affinity Labels; Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Binding, Competitive; Dibenzocycloheptenes; Dioxolanes; Dizocilpine Maleate; Ion Channels; Male; Mice; N-Methylaspartate; Phenazocine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1988 |
Analgesic effects of phencyclidine-like drugs in rhesus monkeys.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Alfentanil; Analgesia; Analgesics; Anesthetics; Animals; Anticonvulsants; Dextrorphan; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Dose-Response Relationship, Drug; Fentanyl; Ketamine; Macaca mulatta; Phenazocine; Phencyclidine; Pyrrolidines | 1989 |
The effects of non-competitive NMDA receptor antagonists on rats exposed to hyperbaric pressure.
Topics: Animals; Binding, Competitive; Dibenzocycloheptenes; Dizocilpine Maleate; Hyperbaric Oxygenation; Ketamine; Male; Myoclonus; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures; Tremor | 1989 |
The behavioural effects of MK-801: a comparison with antagonists acting non-competitively and competitively at the NMDA receptor.
Topics: Animals; Anticonvulsants; Aspartic Acid; Behavior, Animal; Binding, Competitive; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Ketamine; Male; Motor Activity; N-Methylaspartate; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Seizures | 1989 |
Effects of competitive and noncompetitive N-methyl-D-aspartate (NMDA) antagonists in rats trained to discriminate NMDA from saline.
Topics: Amino Acids; Animals; Aspartic Acid; Dibenzocycloheptenes; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Male; N-Methylaspartate; Phenazocine; Piperazines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1989 |
Comparative electroencephalographic and behavioral effects of phencyclidine, (+)-SKF-10,047 and MK-801 in rats.
Topics: Animals; Anticonvulsants; Dibenzocycloheptenes; Dizocilpine Maleate; Electroencephalography; Female; Motor Activity; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, sigma; Stereotyped Behavior | 1989 |
Effects of phencyclidine and other N-methyl-D-aspartate antagonists on the schedule-controlled behavior of rats.
Topics: Animals; Aspartic Acid; Conditioning, Psychological; Dibenzocycloheptenes; Dizocilpine Maleate; Male; N-Methylaspartate; Phenazocine; Phencyclidine; Piperazines; Piperidines; Punishment; Rats; Rats, Inbred Strains; Reinforcement Schedule; Stereoisomerism | 1989 |
[3H]MK-801 labels a site on the N-methyl-D-aspartate receptor channel complex in rat brain membranes.
Topics: Animals; Anticonvulsants; Brain; Cations, Divalent; Cell Membrane; Cerebral Cortex; Dibenzocycloheptenes; Dizocilpine Maleate; Kinetics; Male; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Tissue Distribution; Tritium | 1988 |
Quantitative conformational analyses predict distinct receptor sites for PCP-like and sigma drugs.
Topics: Animals; Binding Sites; Brain; Computer Graphics; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Isoquinolines; Male; Molecular Conformation; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1987 |
Is the discriminative stimulus produced by phencyclidine due to an interaction with N-methyl-D-aspartate receptors?
Topics: Adrenergic beta-Antagonists; Animals; Anticonvulsants; Chlordiazepoxide; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Drug Interactions; Generalization, Stimulus; Male; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter | 1988 |
The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.
Topics: Animals; Anticonvulsants; Aspartic Acid; Binding Sites; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Ketamine; Male; N-Methylaspartate; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains | 1986 |
Intrahippocampal administration of (+)-SKF 10,047, a sigma ligand, reverses MK-801-induced impairment of working memory in rats.
Topics: Animals; Binding Sites; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; Male; Memory; Phenazocine; Rats; Rats, Wistar | 1995 |
Effects of sigma and phencyclidine receptor ligands on electric field-stimulated rabbit ear artery constriction in vitro.
Topics: Animals; Arteries; Dizocilpine Maleate; Ear; Electric Stimulation; Female; In Vitro Techniques; Ligands; Male; Pentazocine; Phenazocine; Phencyclidine; Rabbits; Receptors, Phencyclidine; Receptors, sigma; Vasoconstriction | 1994 |
Low dose of 1,3-di(2-tolyl)guanidine (DTG) attenuates MK-801-induced spatial working memory impairment in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Guanidines; Male; Memory; Mice; Mice, Inbred Strains; Motor Activity; Pentazocine; Phenazocine; Pyrimidines; Receptors, sigma; Space Perception | 1994 |
A comparison of (+)SK&F 10047 and MK-801 on cortical spreading depression.
Topics: Animals; Cerebrovascular Circulation; Cortical Spreading Depression; Dizocilpine Maleate; Dose-Response Relationship, Drug; Electroencephalography; Hyperemia; Injections, Intravenous; Male; Microinjections; N-Methylaspartate; Phenazocine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques | 1994 |
Sigma-1 and sigma-2 sites in rat brain: comparison of regional, ontogenetic, and subcellular patterns.
Topics: Animals; Anticonvulsants; Brain; Brain Chemistry; Dizocilpine Maleate; Female; Guanidines; In Vitro Techniques; Male; Membranes; Phenazocine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, sigma; Subcellular Fractions | 1994 |
Enhancement of the opiate withdrawal response by antipsychotic drugs in guinea-pigs is not mediated by sigma binding sites.
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Atropine; Behavior, Animal; Clozapine; Dizocilpine Maleate; Female; Guinea Pigs; Ketamine; Kinetics; Male; Morphine; Motor Activity; Naloxone; Phenazocine; Raclopride; Radioligand Assay; Receptors, sigma; Remoxipride; Salicylamides; Substance Withdrawal Syndrome | 1993 |
Effect of phencyclidine on contraction of porcine coronary vessel strips.
Topics: Animals; Biological Assay; Coronary Vessels; Dextromethorphan; Dizocilpine Maleate; Haloperidol; In Vitro Techniques; Muscle, Smooth, Vascular; Myocardial Contraction; Phenazocine; Phencyclidine; Receptors, Phencyclidine; Receptors, sigma; Swine | 1993 |
Different sensitivities of NMDA receptor channel subtypes to non-competitive antagonists.
Topics: Amino Acid Sequence; Animals; Dizocilpine Maleate; Ketamine; Magnesium; Molecular Sequence Data; Mutagenesis; Oocytes; Phenazocine; Phencyclidine; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Xenopus | 1993 |
(+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress through the activation of phenytoin-regulated sigma 1 sites.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Dextromethorphan; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Male; Mice; Motor Activity; Phenazocine; Phencyclidine; Phenytoin; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Stress, Physiological | 1996 |
In vivo functional interaction between phencyclidine binding sites and sigma receptors to produce head-weaving behavior in rats.
Topics: Animals; Anisoles; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Guanidines; Male; Phenazocine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, sigma | 1996 |
Sigma receptor ligands (+)-SKF10,047 and SA4503 improve dizocilpine-induced spatial memory deficits in rats.
Topics: Animals; Ataxia; Dizocilpine Maleate; Dose-Response Relationship, Drug; Eating; Excitatory Amino Acid Antagonists; Male; Maze Learning; Memory Disorders; Nootropic Agents; Phenazocine; Piperazines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1998 |
Binding of [3H]desglycinyl remacemide to rat brain membranes: association with the benzomorphan attachment site of the N-methyl-D-aspartic acid receptor channel.
Topics: Animals; Antipsychotic Agents; Benzomorphans; Binding Sites; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Haloperidol; Male; Membrane Proteins; Neurons; Phenazocine; Phencyclidine; Phenethylamines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Subcellular Fractions; Tritium | 1999 |
Modulation of steroidal levels by adrenalectomy/castration and inhibition of neurosteroid synthesis enzymes affect sigma1 receptor-mediated behaviour in mice.
Topics: Adrenalectomy; Animals; Behavior, Animal; Brain; Cerebral Cortex; Dizocilpine Maleate; Enzyme Inhibitors; Finasteride; Hippocampus; Male; Mice; Morpholines; Orchiectomy; Phenazocine; Receptors, sigma; Spatial Behavior; Steroids | 1999 |
Phencyclidine impairs latent learning in mice: interaction between glutamatergic systems and sigma(1) receptors.
Topics: Animals; Antipsychotic Agents; Appetitive Behavior; Behavior, Animal; Cycloserine; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Exploratory Behavior; Glutamic Acid; Learning; Male; Mice; Mice, Inbred Strains; Narcotic Antagonists; Pentazocine; Phenazocine; Phencyclidine; Piperazines; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Stereoisomerism | 2001 |
The anti-amnesic effects of sigma1 (sigma1) receptor agonists confirmed by in vivo antisense strategy in the mouse.
Topics: Amnesia; Animals; Brain; Dizocilpine Maleate; Excitatory Amino Acid Agonists; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Mice; Morpholines; Nootropic Agents; Oligonucleotides, Antisense; Phenazocine; Piperazines; Receptors, sigma | 2001 |
Differential involvement of the sigma(1) (sigma(1)) receptor in the anti-amnesic effect of neuroactive steroids, as demonstrated using an in vivo antisense strategy in the mouse.
Topics: Amnesia; Animals; Avoidance Learning; Behavior, Animal; Binding Sites; Blotting, Western; Brain; Cerebral Cortex; Dehydroepiandrosterone; Dizocilpine Maleate; Dose-Response Relationship, Drug; Hippocampus; In Vitro Techniques; Learning Disabilities; Male; Maze Learning; Memory; Mice; Morpholines; Oligonucleotides, Antisense; Phenazocine; Pregnenolone; Receptors, sigma; Sigma-1 Receptor | 2001 |
Receptor mechanisms and circuitry underlying NMDA antagonist neurotoxicity.
Topics: Adrenergic alpha-Agonists; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Carbazoles; Cerebral Cortex; Clonidine; Dizocilpine Maleate; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Kainic Acid; Models, Neurological; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Phenazocine; Prosencephalon; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Scopolamine | 2002 |
MS-377, a selective sigma receptor ligand, indirectly blocks the action of PCP in the N-methyl-D-aspartate receptor ion-channel complex in primary cultured rat neuronal cells.
Topics: Animals; Antipsychotic Agents; Calcium; Cells, Cultured; Dizocilpine Maleate; Female; Ion Channels; Neurons; Phenazocine; Phencyclidine; Piperazines; Pregnancy; Pyrrolidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sigma-1 Receptor; Tartrates; Tritium | 2002 |
Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro.
Topics: 2-Amino-5-phosphonovalerate; Animals; Calcium; Cell Hypoxia; Cell Survival; Cells, Cultured; Cerebral Cortex; Cyclopentanes; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glucose; Glutamates; Haloperidol; Neurons; Phenazocine; Piperidines; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Sodium Azide | 2002 |
Characterization of the non-competitive antagonist binding site of the NMDA receptor in dark Agouti rats.
Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dioxolanes; Dizocilpine Maleate; Dose-Response Relationship, Drug; Female; Ketamine; N-Methylaspartate; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Mutant Strains; Receptors, N-Methyl-D-Aspartate; Scintillation Counting; Tritium | 2004 |
Inhibition of hyperpolarization-activated cation currents by phencyclidine and some sigma ligands in rat hippocampal CA1 pyramidal neurons in vitro.
Topics: Animals; Animals, Newborn; Cesium; Dizocilpine Maleate; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Ion Channels; Membrane Potentials; Neural Inhibition; Patch-Clamp Techniques; Phenazocine; Phencyclidine; Pyramidal Cells; Pyrimidines; Rats; Rats, Wistar; Receptors, sigma | 2007 |