phenazocine has been researched along with 1,3-ditolylguanidine in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.76) | 18.7374 |
| 1990's | 37 (88.10) | 18.2507 |
| 2000's | 1 (2.38) | 29.6817 |
| 2010's | 2 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hudzik, TJ | 1 |
| Hitosugi, H; Iwamoto, Y; Kamei, J; Kasuya, Y; Kawashima, N; Misawa, M | 1 |
| Ross, SB | 1 |
| Dumont, M; Lemaire, S | 1 |
| Karbon, EW; Naper, K; Pontecorvo, MJ | 1 |
| Burke, M; Earley, B; Gouret, CJ; Junien, JL; Leonard, BE | 1 |
| Balestra, B; Candura, SM; Coccini, T; Costa, LG; Iapadre, N; Manzo, L; Tonini, M | 1 |
| Gillard, J; Knight, AR; Middlemiss, DN; Wong, EH | 1 |
| Brent, PJ | 1 |
| Cristante, D; Itzhak, Y; Kassim, CO; Stein, I; Zhang, SH | 1 |
| Connick, JH; Fox, PK; France, L; Hanlon, GM; Nicholson, CD | 1 |
| Kesingland, AC; Singh, L; Tricklebank, MD; Wong, EH | 1 |
| Bueno, L; Fioramonti, J; Gue, M; Junien, JL; Pascaud, X | 1 |
| Defaux, JP; Junien, JL; Pascaud, X; Rozé, C | 1 |
| Campbell, BG; Galligan, JJ; Kavanaugh, MP; North, RA; Weber, E | 1 |
| Beart, PM; Manallack, DT; O'Shea, RD | 1 |
| Bastianetto, S; Perrault, G; Sanger, DJ | 1 |
| Brent, PJ; Dunkley, PR; Haynes, H; Jarvie, PE; Mudge, L; Sim, AT | 1 |
| Appleyard, SM; Chavkin, C; Connor, M; Patterson, TA | 1 |
| Chariot, J; Nagain, C; Rozé, C | 1 |
| DeCoster, MA; Klette, KL; Knight, ES; Tortella, FC | 1 |
| Matsunaga, KH; Matsuno, K; Mita, S | 1 |
| Hasegawa, T; Hiramatsu, M; Itoh, J; Kameyama, T; Maurice, T; Nabeshima, T | 1 |
| Kamei, H; Kameyama, T; Nabeshima, T | 1 |
| McCann, DJ; Su, TP; Weissman, AD | 1 |
| Matsunaga, K; Matsuno, K; Mita, S; Senda, T | 1 |
| Hara, H; Harada, Y; Sukamoto, T | 1 |
| Brent, PJ; Bunn, SJ; O'Malley, SR | 1 |
| Junien, JL; Pascaud, X; Porreca, F; Rao, RK; Riviere, PJ | 1 |
| Cuomo, V; d'Istria, M; Maj, M; Monteleone, P; Serino, I; Steardo, L | 1 |
| Kobayashi, T; Matsuno, K; Mita, S | 2 |
| Bowen, WD; Torrence-Campbell, C | 1 |
| Ha, BK; Saini, P; Whitlock, BB; Wolfe, SA | 1 |
| Furukawa, H; Hasegawa, T; Kitaichi, K; Nabeshima, T; Noda, Y | 1 |
| Kobayashi, T; Matsuno, K; Mita, S; Senda, T | 1 |
| Bucolo, C; Cacciaguerra, S; Campana, G; Di Toro, R; Spampinato, S | 1 |
| Kamei, J | 1 |
| Ishihara, K; Sasa, M | 1 |
| Furukawa, S; Hiramatsu, M; Kameyama, T; Karasawa, K; Mamiya, T; Nabeshima, T; Noda, A; Noda, Y; Yamada, K | 1 |
| Fontanilla, D; Jackson, MB; Johannessen, M; Mavlyutov, T; Ruoho, AE | 1 |
| Gao, XF; He, YL; Hu, C; Mei, YA; Yao, JJ | 1 |
2 review(s) available for phenazocine and 1,3-ditolylguanidine
| Article | Year |
|---|---|
[Possible role of sigma-receptors in the regulation of cough reflex, gastrointestinal and retinal function].
Topics: Animals; Anti-Ulcer Agents; Antitussive Agents; Carbazoles; Guanidines; Haloperidol; Humans; Ligands; Pentazocine; Phenazocine; Receptors, N-Methyl-D-Aspartate; Receptors, sigma; Retinal Diseases | 1999 |
[The function of sigma receptors--electrophysiological approach].
Topics: Animals; Electrophysiology; Guanidines; Hippocampus; Ligands; Phenazocine; Pyrimidines; Receptors, N-Methyl-D-Aspartate; Receptors, sigma | 1999 |
40 other study(ies) available for phenazocine and 1,3-ditolylguanidine
| Article | Year |
|---|---|
Sigma ligand-induced emesis in the pigeon.
Topics: Animals; Apomorphine; Columbidae; Dextromethorphan; Dizocilpine Maleate; Dopamine Agents; Guanidines; Haloperidol; Male; Pentobarbital; Phenazocine; Piperidines; Propranolol; Psychotropic Drugs; Pyrimidines; Receptors, Opioid; Receptors, sigma; Vomiting | 1992 |
Involvement of haloperidol-sensitive sigma-sites in antitussive effects.
Topics: Animals; Antitussive Agents; Capsaicin; Cough; Dose-Response Relationship, Drug; Drug Interactions; Guanidines; Haloperidol; Injections, Intraperitoneal; Male; Phenazocine; Rats; Rats, Sprague-Dawley; Receptors, sigma; Stereoisomerism | 1992 |
Heterogeneous binding of sigma radioligands in the rat brain and liver: possible relationship to subforms of cytochrome P-450.
Topics: Animals; Brain; Cytochrome P-450 Enzyme System; Guanidines; Haloperidol; Kinetics; Ligands; Liver; Male; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Subcellular Fractions | 1991 |
Interaction of 1,3-di(2-[5-3H]tolyl) guanidine with sigma 2 binding sites in rat heart membrane preparations.
Topics: Animals; Guanidines; Heart; In Vitro Techniques; Kinetics; Ligands; Male; Membranes; Myocardium; Phenazocine; Rats; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Phencyclidine; Receptors, sigma | 1991 |
[3H]DTG and [3H](+)-3-PPP label pharmacologically distinct sigma binding sites in guinea pig brain membranes.
Topics: Animals; Binding, Competitive; Brain; Dextromethorphan; Dopamine Agents; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Kinetics; Membranes; Phenazocine; Phenytoin; Piperidines; Receptors, Opioid; Receptors, sigma | 1991 |
Evidence for an anti-amnesic effect of JO 1784 in the rat: a potent and selective ligand for the sigma receptor.
Topics: Amnesia; Animals; Antipsychotic Agents; Avoidance Learning; Behavior, Animal; Carbazoles; Cinnamates; Cyclopropanes; Dopamine Agents; Dose-Response Relationship, Drug; Guanidines; Ligands; Male; Phenazocine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Scopolamine | 1991 |
Two subtypes of enteric non-opioid sigma receptors in guinea-pig cholinergic motor neurons.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Carbazoles; Dextromethorphan; Electric Stimulation; Guanidines; Guinea Pigs; Haloperidol; In Vitro Techniques; Male; Motor Neurons; Myenteric Plexus; Parasympathetic Nervous System; Phenazocine; Pyrimidines; Receptors, Opioid; Receptors, sigma | 1991 |
The human sigma site, which resembles that in NCB20 cells, may correspond to a low-affinity site in guinea pig brain.
Topics: Animals; Brain Chemistry; Cells, Cultured; Cerebral Cortex; Cricetinae; Cricetulus; Dopamine Agents; Guanidines; Guinea Pigs; Humans; Kinetics; Male; Mice; Neuroblastoma; Pentazocine; Phenazocine; Piperidines; Radioligand Assay; Receptors, Opioid; Receptors, sigma; Stereoisomerism; Tumor Cells, Cultured | 1991 |
Similar behavioural effects of sigma agonists and PCP-like non-competitive NMDA antagonists in guinea-pigs.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzamides; Dizocilpine Maleate; Dopamine Agents; Dopamine Antagonists; Ergolines; Female; Guanidines; Guinea Pigs; Haloperidol; Ketamine; Male; Motor Activity; N-Methylaspartate; Pentazocine; Phenazocine; Phencyclidine; Quinpirole; Receptors, Dopamine D2; Receptors, Opioid; Receptors, sigma; Remoxipride | 1991 |
Binding of sigma-ligands to C57BL/6 mouse brain membranes: effects of monoamine oxidase inhibitors and subcellular distribution studies suggest the existence of sigma-receptor subtypes.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Binding Sites; Brain; Guanidines; In Vitro Techniques; Ligands; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase Inhibitors; Phenazocine; Piperidines; Receptors, Opioid; Receptors, sigma | 1991 |
The lack of utility of the rat vas deferens as a functional bioassay for sigma ligands.
Topics: Animals; Binding Sites; Biological Assay; Electric Stimulation; Guanidines; Guinea Pigs; Haloperidol; Male; Muscle Contraction; Pentazocine; Phenazocine; Phencyclidine; Rats; Rats, Inbred Strains; Vas Deferens | 1991 |
Evidence against an involvement of the haloperidol-sensitive sigma recognition site in the discriminative stimulus properties of (+)-N-allylnormetazocine ((+)-SKF 10,047).
Topics: Animals; Aspartic Acid; Binding, Competitive; Dibenzocycloheptenes; Discrimination, Psychological; Dizocilpine Maleate; Guanidines; Haloperidol; Male; Mice; N-Methylaspartate; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, delta; Seizures | 1990 |
Selective stimulation of colonic motor response to a meal by sigma ligands in dogs.
Topics: Animals; Cinnamates; Colon; Cyclopropanes; Dogs; Drug Antagonism; Eating; Gastrointestinal Motility; Guanidines; Injections, Intravenous; Injections, Intraventricular; Phenazocine; Phencyclidine; Receptors, Opioid; Receptors, sigma; Stereoisomerism | 1990 |
Effect of selective sigma ligands on duodenal alkaline secretion in the rat.
Topics: Animals; Atropine; Bicarbonates; Dose-Response Relationship, Drug; Duodenum; Guanidines; Haloperidol; Injections, Intravenous; Intestinal Mucosa; Intestinal Secretions; Male; Naloxone; Phenazocine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma; Yohimbine | 1990 |
1,3-Di(2-tolyl)guanidine blocks nicotinic response in guinea pig myenteric neurons.
Topics: Animals; Ganglionic Stimulants; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Membrane Potentials; Myenteric Plexus; Neurons; Phenazocine; Receptors, Opioid; Receptors, sigma | 1989 |
Regulation of sigma-receptors: high- and low-affinity agonist states, GTP shifts, and up-regulation by rimcazole and 1,3-Di(2-tolyl)guanidine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Brain; Carbazoles; Cyclazocine; Dopamine; Dopamine Agents; GTP-Binding Proteins; Guanidines; Guanosine Triphosphate; Magnesium; Male; Phenazocine; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, sigma | 1989 |
Pharmacological evidence for the involvement of sigma sites in DTG-induced contralateral circling in rats.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbazoles; Dose-Response Relationship, Drug; Guanidines; Haloperidol; Injections, Spinal; Male; Motor Activity; Phenazocine; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, sigma; Salicylamides | 1995 |
Phosphorylation of synapsin I and dynamin in rat forebrain synaptosomes: modulation by sigma (sigma) ligands.
Topics: Animals; Anticonvulsants; Dynamins; GTP Phosphohydrolases; Guanidines; Haloperidol; In Vitro Techniques; Microtubules; Pentazocine; Phenazocine; Phosphorylation; Prosencephalon; Rats; Receptors, sigma; Synapsins; Synaptosomes | 1995 |
Oocytes from Xenopus laevis contain an intrinsic sigma 2-like binding site.
Topics: Animals; Binding Sites; Binding, Competitive; Carbazoles; Dextromethorphan; Female; Guanidines; Haloperidol; Liver; Mazindol; Oocytes; Pentazocine; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, sigma; Xenopus laevis; Zinc | 1994 |
Differential effects of peptide YY, neuropeptide Y, and sigma ligands on neurally stimulated external pancreatic secretion in the rat.
Topics: Animals; Fistula; Guanidines; Male; Neuropeptide Y; Pancreas; Peptide YY; Peptides; Phenazocine; Rats; Rats, Wistar | 1995 |
Sigma receptor-mediated neuroprotection against glutamate toxicity in primary rat neuronal cultures.
Topics: Animals; Calcium; Cells, Cultured; Cyclazocine; Cyclopentanes; Dextromethorphan; Glutamic Acid; Guanidines; Haloperidol; L-Lactate Dehydrogenase; Neurons; Neuroprotective Agents; Pentazocine; Phenazocine; Piperidines; Rats; Receptors, sigma | 1995 |
Acute effects of sigma ligands on the extracellular DOPAC level in rat frontal cortex and striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anticonvulsants; Antipsychotic Agents; Carbazoles; Corpus Striatum; Extracellular Space; Frontal Lobe; Guanidines; Kinetics; Ligands; Male; Microdialysis; Pentazocine; Phenazocine; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Time Factors | 1995 |
Low dose of 1,3-di(2-tolyl)guanidine (DTG) attenuates MK-801-induced spatial working memory impairment in mice.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Dizocilpine Maleate; Dose-Response Relationship, Drug; Guanidines; Male; Memory; Mice; Mice, Inbred Strains; Motor Activity; Pentazocine; Phenazocine; Pyrimidines; Receptors, sigma; Space Perception | 1994 |
SKF-10,047 reverses stress-induced motor suppression: interaction with dopaminergic system.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anticonvulsants; Apomorphine; Dopamine; Electroshock; Guanidines; Male; Methamphetamine; Mice; Mice, Inbred Strains; Motor Activity; Oxidopamine; Pentazocine; Phenazocine; Pimozide; Pyrimidines; Receptors, sigma; Stress, Psychological | 1994 |
Sigma-1 and sigma-2 sites in rat brain: comparison of regional, ontogenetic, and subcellular patterns.
Topics: Animals; Anticonvulsants; Brain; Brain Chemistry; Dizocilpine Maleate; Female; Guanidines; In Vitro Techniques; Male; Membranes; Phenazocine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, sigma; Subcellular Fractions | 1994 |
Ameliorating effects of sigma receptor ligands on the impairment of passive avoidance tasks in mice: involvement in the central acetylcholinergic system.
Topics: Acetylcholine; Amnesia; Animals; Anticonvulsants; Avoidance Learning; Brain; Cholinesterase Inhibitors; Dopamine Agonists; Electroshock; Guanidines; Ligands; Male; Memory; Mice; Mice, Inbred Strains; p-Chloroamphetamine; Phenazocine; Piperidines; Receptors, sigma; Serotonin Antagonists | 1994 |
Characterization of specific (+)-[3H]N-allylnormetazocine and [3H]1,3-di(2-tolyl)guanidine binding sites in porcine gastric fundic mucosa.
Topics: Animals; Binding Sites; Gastric Fundus; Gastric Mucosa; Guanidines; Haloperidol; Phenazocine; Receptors, sigma; Swine | 1994 |
The sigma compounds 1,3-di-o-tolylguanidine and N-allylnormetazocine inhibit agonist-stimulated inositol phospholipid metabolism in bovine adrenal medullary cells.
Topics: Adrenal Medulla; Angiotensin II; Animals; Anticonvulsants; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Guanidines; Histamine; Inositol; Inositol Phosphates; Kinetics; Muscarine; Phenazocine; Phosphatidylinositols; Tritium | 1994 |
Effects of neuropeptide Y, peptide YY and sigma ligands on ion transport in mouse jejunum.
Topics: Animals; Cinnamates; Cyclopropanes; Guanidines; In Vitro Techniques; Ion Transport; Jejunum; Male; Mice; Mice, Inbred ICR; Neuropeptide Y; Peptide YY; Peptides; Phenazocine; Receptors, sigma | 1993 |
Sigma receptor modulation of noradrenergic-stimulated pineal melatonin biosynthesis in rats.
Topics: Animals; Anticonvulsants; Antipsychotic Agents; Arylamine N-Acetyltransferase; Circadian Rhythm; Darkness; Guanidines; Isoproterenol; Male; Melatonin; Norepinephrine; Phenazocine; Pineal Gland; Rats; Rats, Wistar; Receptors, sigma; Sympathomimetics | 1996 |
Involvement of sigma-receptors in the increase in contraction of mouse vas deferens induced by exogenous ATP.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Anticonvulsants; Antipsychotic Agents; Carbazoles; Dopamine Agonists; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Haloperidol; Ligands; Male; Mice; Muscle Contraction; Muscle, Smooth; Pentazocine; Phenazocine; Piperidines; Receptors, sigma; Regression Analysis; Structure-Activity Relationship; Vas Deferens | 1996 |
Differential solubilization of rat liver sigma 1 and sigma 2 receptors: retention of sigma 2 sites in particulate fractions.
Topics: Animals; Binding, Competitive; Cell Fractionation; Cell Membrane; Cholic Acids; Detergents; Guanidines; Haloperidol; In Vitro Techniques; Liver; Male; Pentazocine; Phenazocine; Protein Binding; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, sigma; Solubility; Subcellular Fractions | 1996 |
Regional differences of the effect of sigma receptor ligands on the acetylcholine release in the rat brain.
Topics: Acetylcholine; Animals; Anticonvulsants; Antipsychotic Agents; Brain Chemistry; Extracellular Space; Guanidines; Hippocampus; Ligands; Male; Neostriatum; Neurotransmitter Agents; Phenazocine; Rats; Rats, Wistar; Receptors, sigma | 1996 |
Differential localization of three distinct binding sites for sigma receptor ligands in rat spleen.
Topics: Analgesics, Opioid; Animals; Anticonvulsants; Antipsychotic Agents; Autoradiography; Binding Sites; Dopamine Agonists; Dopamine Antagonists; Female; Guanidines; Haloperidol; Image Processing, Computer-Assisted; Ligands; Male; Naltrexone; Narcotic Antagonists; Pentazocine; Phenazocine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, sigma; Spleen; Tritium | 1997 |
In vivo functional interaction between phencyclidine binding sites and sigma receptors to produce head-weaving behavior in rats.
Topics: Animals; Anisoles; Behavior, Animal; Binding Sites; Dizocilpine Maleate; Guanidines; Male; Phenazocine; Piperidines; Propylamines; Pyrimidines; Rats; Rats, Wistar; Receptors, Phencyclidine; Receptors, sigma | 1996 |
Reduction of the scopolamine-induced impairment of passive-avoidance performance by sigma receptor agonist in mice.
Topics: Acetylcholinesterase; Animals; Antipsychotic Agents; Avoidance Learning; Brain; Dose-Response Relationship, Drug; Guanidines; Male; Mental Recall; Mice; Mice, Inbred Strains; Phenazocine; Piperidines; Receptors, sigma; Scopolamine | 1997 |
Sigma1 recognition sites in rabbit iris-ciliary body: topical sigma1-site agonists lower intraocular pressure.
Topics: Animals; Anisoles; Antipsychotic Agents; Binding, Competitive; Cell Membrane; Ciliary Body; Functional Laterality; Guanidines; Intraocular Pressure; Iris; Kinetics; Lens, Crystalline; Male; Pentazocine; Phenazocine; Propylamines; Rabbits; Receptors, sigma; Retina; Tritium | 1999 |
Effects of sigma receptor agonists on the impairment of spontaneous alternation behavior and decrease of cyclic GMP level induced by nitric oxide synthase inhibitors in mice.
Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Antipsychotic Agents; Behavior, Animal; Brain Chemistry; Cyclic GMP; Enzyme Inhibitors; Guanidines; Indazoles; Male; Methylene Blue; Mice; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pentazocine; Phenazocine; Pyrimidines; Receptors, sigma | 2000 |
Antagonist action of progesterone at σ-receptors in the modulation of voltage-gated sodium channels.
Topics: Animals; Cells, Cultured; Guanidines; HEK293 Cells; Humans; Liver; N,N-Dimethyltryptamine; NAV1.5 Voltage-Gated Sodium Channel; Phenazocine; Piperazines; Progesterone; Rats; Receptors, sigma; RNA, Small Interfering; Sigma-1 Receptor; Sodium Channels | 2011 |
Sigma-1 receptor agonists directly inhibit Nav1.2/1.4 channels.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cyclic AMP-Dependent Protein Kinases; Dextromethorphan; GTP-Binding Proteins; Guanidines; HEK293 Cells; Humans; Ion Channel Gating; Lidocaine; Muscle Proteins; Mutagenesis, Site-Directed; Mutant Proteins; Mutation; NAV1.2 Voltage-Gated Sodium Channel; Neurons; Phenazocine; Protein Kinase C; Protein Kinase Inhibitors; Rats; Receptors, sigma; Sigma-1 Receptor; Signal Transduction; Sodium Channels; Transfection | 2012 |