phenanthridone and phenanthrenes

phenanthridone has been researched along with phenanthrenes in 41 studies

Research

Studies (41)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.88)18.7374
1990's6 (14.63)18.2507
2000's15 (36.59)29.6817
2010's17 (41.46)24.3611
2020's1 (2.44)2.80

Authors

AuthorsStudies
Mangold, BL; Mangold, JB; Spina, A1
Mitchell, CE1
Aupeix, K; Bischoff, P; Dufour, P; Marchal, J; Oth, D; Picard, V; Varin, M; Weltin, D1
Bischoff, P; Dufour, P; Marchal, J; Oth, D; Potworowski, E; Weltin, D1
Polya, GM; Ternai, B; Wang, BH1
Bischoff, P; Dufour, P; Holl, V; Hyun, JW; Marchal, J; Weltin, D1
Cookson, MR; Ince, PG; Shaw, PJ1
Allen, PD; Kelsey, SM; Newland, AC; Richardson, DS1
Gras, S; Hill, BT; Perrin, D; van Hille, B1
Barthmaier, P; Couto, J; Francesco, M; Jain, A; Jarnagin, K; Melese, T; Morgans, D; Nguyen, A; Nguyen, H; Perkins, E; Sun, D; Tavana, H; Thode, S; Tugendreich, S; Tulac, S; Yeh, E1
Chiarugi, A; Cozzi, A; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Peruginelli, F; Picca, R; Romagnoli, P1
Baloglu, E; Gallyas, F; Haskó, G; Hoyt, DG; Jagtap, P; Liaudet, L; Lorigados, CB; Mabley, J; Marton, A; Salzman, AL; Soriano, FG; Southan, GJ; Sümegi, B; Szabó, C; Szabó, E; VanDuzer, J; Virág, L1
Balakrishnan, M; Murugan, A; Pandey, G1
Chiarugi, A1
Blömback, M; Söderström, T; Ungerstedt, JS1
Baronti, R; Calvani, M; Camaioni, E; Chiarugi, A; Costantino, G; Marinozzi, M; Meli, E; Moroni, F; Pellegrini-Giampietro, DE; Pellicciari, R; Picca, R1
Adamson, AW; Beardsley, DI; Brown, KD; Kim, WJ1
Padwa, A; Zhang, H1
Banasik, M; Harbison, RD; Muro-Cacho, C; Stedeford, T; Su, PH; Tanaka, S; Ueda, K1
Fooladi, E; Naseri, A; Rashidi, MR; Sorouraddin, MH1
Collins, J; Drouin, M; Hudlicky, T; Rinner, U; Sun, X1
Admiraal, W; Kraak, MH; Paumen, ML; Stol, P; Ter Laak, TL; Van Gestel, CA1
Cho, WJ; Kwon, Y; Lee, KT; Lee, SH; Van, HT; Yang, SH1
Bindra, RS; Crosby, ME; Glazer, PM; Hegan, DC; Lu, Y; Stachelek, GC1
Li, DD; Wang, GW; Yuan, TT1
Kuzhandaivel, A; Mladinic, M; Nasrabady, SE; Nistri, A1
Aldinucci, A; Ballerini, C; Biagioli, T; Cavone, L; Chiarugi, A; Moroni, F1
Banasik, M; Stedeford, T; Strosznajder, RP; Takehashi, M; Tanaka, S; Ueda, K1
Hwang, S; Jang, W; Kim, S; Lee, S; Lee, YM; Yu, S1
Ahmad, S; Farrugia, LJ; Senn, HM; Sutherland, A; Swift, MD1
El Sayed, KA; Ibrahim, SR; Mohamed, GA; Shaala, LA; Youssef, DT1
Nair, JJ; van Staden, J1
Hashimoto, Y; Ishikawa, M; Makishima, M; Misawa, T; Nakagomi, M; Nakamura, M; Nishiyama, Y1
Jeganmohan, M; Pimparkar, S1
Caligo, MA; Cervelli, T; Galli, A; La Ferla, M; Lodovichi, S; Mercatanti, A; Pignata, L; Rocchi, G1
Feng, M; Jiang, X; Tang, B; Wang, N; Xu, HX1
Baba, M; Hashimoto, Y; Ikeda, M; Ito, W; Okamoto, M; Toyama, M; Wakita, T; Watashi, K1
Kumar, M; Kumar, N; Nayal, OS; Sharma, S; Sharma, U; Singh, B1
Deshmukh, P; Marimuthu, P; Mathur, S; Padmanabhan, B; Tripathi, S1
Chen, ZJ; Feng, Q; Gao, TT; Hu, QF; Lei, Q; Liu, ZH; Shi, YJ; Yu, LT1
Chen, D; Fan, S; Liang, S; Liu, G; Wang, Y; Zhang, S; Zhang, Y1

Reviews

1 review(s) available for phenanthridone and phenanthrenes

ArticleYear
Pharmacological and toxicological insights to the South African Amaryllidaceae.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 62

    Topics: Alkaloids; Amaryllidaceae Alkaloids; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antifungal Agents; Antiparasitic Agents; Ethnopharmacology; Hallucinogens; Humans; Isoquinolines; Liliaceae; Medicine, African Traditional; Mental Disorders; Neoplasms; Phenanthrenes; Plants, Medicinal; Plants, Toxic; South Africa

2013

Other Studies

40 other study(ies) available for phenanthridone and phenanthrenes

ArticleYear
Rat liver aryl sulfotransferase-catalyzed sulfation and rearrangement of 9-fluorenone oxime.
    Biochimica et biophysica acta, 1986, Nov-07, Volume: 874, Issue:1

    Topics: Animals; Arylsulfotransferase; Fluorenes; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Phenanthrenes; Rats; Rats, Inbred Strains; Sulfuric Acids; Sulfurtransferases

1986
Effect of aryl hydrocarbon hydroxylase induction on the in vivo covalent binding of 1-nitropyrene, benzo[a]pyrene, 2-aminoanthracene, and phenanthridone to mouse lung deoxyribonucleic acid.
    Biochemical pharmacology, 1985, Feb-15, Volume: 34, Issue:4

    Topics: Animals; Anthracenes; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Binding Sites; Chlorodiphenyl (54% Chlorine); Coal; Cytochrome P-450 Enzyme System; DNA; Dose-Response Relationship, Drug; Enzyme Induction; Lung; Male; Mice; Oxygenases; Phenanthrenes; Polycyclic Compounds; Pyrenes

1985
Immunosuppressive activities of 6(5H)-phenanthridinone, a new poly(ADP-ribose)polymerase inhibitor.
    International journal of immunopharmacology, 1995, Volume: 17, Issue:4

    Topics: Acridines; Acridones; Animals; Benzamides; Cells, Cultured; Concanavalin A; Female; Gamma Rays; Immunosuppressive Agents; Interleukin-2; Isoquinolines; Killer Cells, Lymphokine-Activated; Lymphocyte Activation; Lymphocyte Culture Test, Mixed; Lymphocytes; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Recombinant Proteins; Spleen; T-Lymphocytes, Cytotoxic

1995
Effect of 6(5H)-phenanthridinone, an inhibitor of poly(ADP-ribose) polymerase, on cultured tumor cells.
    Oncology research, 1994, Volume: 6, Issue:9

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Cell Survival; Drug Screening Assays, Antitumor; Drug Synergism; Lymphoma; Mechlorethamine; Mice; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured

1994
Specific inhibition of cyclic AMP-dependent protein kinase by the antimalarial halofantrine and by related phenanthrenes.
    Biological chemistry Hoppe-Seyler, 1994, Volume: 375, Issue:8

    Topics: Amino Acid Sequence; Animals; Antimalarials; Cattle; Cyclic AMP-Dependent Protein Kinases; Heart; Liver; Molecular Sequence Data; Myocardium; Myosin-Light-Chain Kinase; Phenanthrenes; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Structure-Activity Relationship

1994
Effect of 6(5H)-phenanthridinone, a poly (ADP-ribose)polymerase inhibitor, and ionizing radiation on the growth of cultured lymphoma cells.
    International journal of radiation biology, 1997, Volume: 72, Issue:6

    Topics: Animals; Apoptosis; Cell Cycle; DNA Damage; Enzyme Inhibitors; Lymphoma; Mice; Mice, Inbred AKR; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured

1997
Peroxynitrite and hydrogen peroxide induced cell death in the NSC34 neuroblastoma x spinal cord cell line: role of poly (ADP-ribose) polymerase.
    Journal of neurochemistry, 1998, Volume: 70, Issue:2

    Topics: Animals; Benzamides; Cell Death; Cell Survival; Dactinomycin; DNA Damage; Enzyme Inhibitors; Hybrid Cells; Hydrogen Peroxide; Kinetics; Neuroblastoma; Niacinamide; Nitrates; Oxidants; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Spinal Cord

1998
Effects of PARP inhibition on drug and Fas-induced apoptosis in leukaemic cells.
    Advances in experimental medicine and biology, 1999, Volume: 457

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Drug Resistance, Multiple; Enzyme Inhibitors; Etoposide; fas Receptor; Genes, MDR; HL-60 Cells; Humans; Idarubicin; Leukemia-Lymphoma, Adult T-Cell; Microtubules; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Tumor Cells, Cultured; Vidarabine; Vinblastine

1999
Expression in yeast and purification of functional recombinant human poly(ADP-ribose)polymerase (PARP). Comparative pharmacological profile with that of the rat enzyme.
    Journal of enzyme inhibition, 2000, Volume: 15, Issue:5

    Topics: 1-Naphthylamine; Animals; Benzamides; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Gene Expression; Humans; Kinetics; Male; Naphthalimides; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Quinazolines; Quinolones; Rats; Recombinant Proteins; Saccharomyces; Sensitivity and Specificity; Testis

2000
Novel inhibitors of poly(ADP-ribose) polymerase/PARP1 and PARP2 identified using a cell-based screen in yeast.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: ATP-Binding Cassette Transporters; Binding Sites; Drug Evaluation, Preclinical; Enzyme Inhibitors; Gene Expression; Humans; Isoenzymes; Membrane Proteins; Mutation; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2001
Poly(ADP-ribose) polymerase inhibitors attenuate necrotic but not apoptotic neuronal death in experimental models of cerebral ischemia.
    Cell death and differentiation, 2001, Volume: 8, Issue:9

    Topics: Animals; Apoptosis; Benzamides; Brain Ischemia; Caspase 3; Caspases; Cell Death; Cell Line; Cerebral Cortex; Enzyme Inhibitors; Gerbillinae; In Vitro Techniques; Isoquinolines; Microscopy, Electron; Microscopy, Fluorescence; Necrosis; Neurons; Neuroprotective Agents; Phenanthrenes; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyramidal Cells; Rats; Rats, Wistar

2001
Novel phenanthridinone inhibitors of poly (adenosine 5'-diphosphate-ribose) synthetase: potent cytoprotective and antishock agents.
    Critical care medicine, 2002, Volume: 30, Issue:5

    Topics: Animals; Bleomycin; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Interleukin-1; Kidney; Lipopolysaccharides; Lung; Malondialdehyde; Mice; Mice, Inbred BALB C; Nitrates; Nitrites; Peroxidase; Peroxynitrous Acid; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Shock; Tumor Necrosis Factor-alpha

2002
A new strategy towards the total synthesis of phenanthridone alkaloids: synthesis of (+)-2,7-dideoxypancratistatin as a model study.
    Chemical communications (Cambridge, England), 2002, Mar-21, Issue:6

    Topics: Amaryllidaceae Alkaloids; Antineoplastic Agents; Antiviral Agents; Isoquinolines; Phenanthrenes; Quinic Acid

2002
Inhibitors of poly(ADP-ribose) polymerase-1 suppress transcriptional activation in lymphocytes and ameliorate autoimmune encephalomyelitis in rats.
    British journal of pharmacology, 2002, Volume: 137, Issue:6

    Topics: Adenosine Triphosphate; Animals; Benzamides; Benzoic Acid; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Interferon-gamma; Interleukin-2; Lymph Nodes; Lymphocytes; NAD; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred Lew; RNA, Messenger; Spinal Cord; Time Factors; Transcriptional Activation; Tumor Necrosis Factor-alpha

2002
Nicotinamide is a potent inhibitor of proinflammatory cytokines.
    Clinical and experimental immunology, 2003, Volume: 131, Issue:1

    Topics: Adjuvants, Immunologic; Cells, Cultured; Cytokines; Depression, Chemical; Dose-Response Relationship, Drug; Endotoxemia; Enzyme Inhibitors; Humans; Interleukin-1; Interleukin-6; Interleukin-8; Niacinamide; Phenanthrenes; Poly Adenosine Diphosphate Ribose; Tumor Necrosis Factor-alpha

2003
Novel isoquinolinone-derived inhibitors of poly(ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:3

    Topics: Animals; Brain Ischemia; Cells, Cultured; Disease Models, Animal; Isoquinolines; Mice; Neuroprotective Agents; Phenanthrenes; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Thiophenes

2003
The monofunctional alkylating agent N-methyl-N'-nitro-N-nitrosoguanidine triggers apoptosis through p53-dependent and -independent pathways.
    Toxicology and applied pharmacology, 2005, Jan-01, Volume: 202, Issue:1

    Topics: Apoptosis; Benzamides; Caspase 3; Caspase 9; Caspases; Cell Line; Checkpoint Kinase 2; Humans; Methylnitronitrosoguanidine; Mitochondria; Phenanthrenes; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Tumor Suppressor Protein p53

2005
Synthesis of some members of the hydroxylated phenanthridone subclass of the Amaryllidaceae alkaloid family.
    The Journal of organic chemistry, 2007, Mar-30, Volume: 72, Issue:7

    Topics: Acids; Amaryllidaceae Alkaloids; Catalysis; Hydroxylation; Ions; Isomerism; Liliaceae; Models, Chemical; Molecular Structure; Oxidation-Reduction; Phenanthrenes; Phenanthridines

2007
Hepatoprotective effects of 6(5H)-phenanthridinone from chemical-induced centrilobular necrosis.
    Research communications in molecular pathology and pharmacology, 2004, Volume: 115-116

    Topics: Alanine Transaminase; Animals; Apoptosis; Aspartate Aminotransferases; Carbon Tetrachloride Poisoning; Histocytochemistry; Male; Mice; Mice, Inbred ICR; Necrosis; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Protective Agents

2004
A novel spectrophotometric method for determination of kinetic constants of aldehyde oxidase using multivariate calibration method.
    Journal of biochemical and biophysical methods, 2008, Apr-24, Volume: 70, Issue:6

    Topics: Aldehyde Oxidase; Animals; Calibration; Hydrogen-Ion Concentration; Kinetics; Male; Molecular Structure; Oxidation-Reduction; Phenanthrenes; Phenanthridines; Rats; Rats, Sprague-Dawley; Spectrophotometry

2008
Total synthesis of 7-deoxypancratistatin-1-carboxaldehyde and carboxylic acid via solvent-free intramolecular aziridine opening: phenanthrene to phenanthridone cyclization strategy.
    Organic letters, 2008, Feb-07, Volume: 10, Issue:3

    Topics: Amaryllidaceae Alkaloids; Aziridines; Carboxylic Acids; Catalysis; Cyclization; Isoquinolines; Molecular Structure; Phenanthrenes

2008
Chronic exposure of the oligochaete Lumbriculus variegatus to polycyclic aromatic compounds (PACs): bioavailability and effects on reproduction.
    Environmental science & technology, 2008, May-01, Volume: 42, Issue:9

    Topics: Acridines; Acridones; Animals; Anthracenes; Biological Availability; Dose-Response Relationship, Drug; Environmental Monitoring; Kinetics; Narcotics; Oligochaeta; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Risk Assessment; Water; Water Pollutants, Chemical

2008
Molecular design, synthesis and docking study of benz[b]oxepines and 12-oxobenzo[c]phenanthridinones as topoisomerase 1 inhibitors.
    Bioorganic & medicinal chemistry letters, 2009, May-01, Volume: 19, Issue:9

    Topics: Antineoplastic Agents; Benzoxepins; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; DNA Topoisomerases, Type I; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; HeLa Cells; Humans; Models, Chemical; Molecular Conformation; Phenanthrenes; Protein Binding; Topoisomerase I Inhibitors

2009
Inhibition of poly(ADP-ribose) polymerase down-regulates BRCA1 and RAD51 in a pathway mediated by E2F4 and p130.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-02, Volume: 107, Issue:5

    Topics: Cell Line, Tumor; Colonic Neoplasms; Crk-Associated Substrate Protein; DNA Repair; Down-Regulation; E2F4 Transcription Factor; Enzyme Inhibitors; Genes, BRCA1; Humans; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Promoter Regions, Genetic; Rad51 Recombinase; Radiation-Sensitizing Agents; RNA, Small Interfering

2010
One-pot formation of C-C and C-N bonds through palladium-catalyzed dual C-H activation: synthesis of phenanthridinones.
    Angewandte Chemie (International ed. in English), 2011, Feb-07, Volume: 50, Issue:6

    Topics: Benzamides; Carbon; Catalysis; Crystallography, X-Ray; Hydrogen; Molecular Conformation; Nitrogen; Palladium; Phenanthrenes

2011
Effects of 6(5H)-phenanthridinone, an inhibitor of poly(ADP-ribose)polymerase-1 activity (PARP-1), on locomotor networks of the rat isolated spinal cord.
    Cellular and molecular neurobiology, 2011, Volume: 31, Issue:4

    Topics: Animals; Electrophysiological Phenomena; Enzyme Inhibitors; In Vitro Techniques; Kainic Acid; Locomotion; Motor Neurons; Neurotoxins; Phenanthrenes; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Spinal Cord

2011
PARP-1 inhibition prevents CNS migration of dendritic cells during EAE, suppressing the encephalitogenic response and relapse severity.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2011, Volume: 17, Issue:7

    Topics: Analysis of Variance; Animals; Antigen Presentation; Autoimmunity; Cell Movement; Cells, Cultured; Central Nervous System; Cytokines; Dendritic Cells; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Ovalbumin; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Recurrence; Severity of Illness Index; Th17 Cells; Time Factors

2011
Inhibition of poly(ADP-ribose) polymerase-1 attenuates the toxicity of carbon tetrachloride.
    Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:6

    Topics: Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Enzyme Inhibitors; Injections, Intraperitoneal; Liver; Male; Mice; Mice, Inbred ICR; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Structure-Activity Relationship

2011
Synthesis and evaluation of C-ring aromatized analogues of phenanthridone alkaloids.
    Archives of pharmacal research, 2011, Volume: 34, Issue:7

    Topics: Alkaloids; Amaryllidaceae Alkaloids; Antineoplastic Agents; Cell Line, Tumor; Drug Design; Drug Discovery; Drug Screening Assays, Antitumor; Electrophysiological Phenomena; Humans; Inhibitory Concentration 50; Models, Chemical; Phenanthrenes; Stereoisomerism; Structure-Activity Relationship

2011
Stereoselective synthesis of functionalised carbocyclic amides: construction of the syn-(4aS,10bS)-phenanthridone skeleton.
    Organic & biomolecular chemistry, 2012, May-21, Volume: 10, Issue:19

    Topics: Amides; Epoxy Compounds; Models, Molecular; Molecular Structure; Phenanthrenes; Stereoisomerism

2012
New alkaloids from Pancratium maritimum.
    Planta medica, 2013, Volume: 79, Issue:15

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Dioxoles; Flowers; Humans; Liliaceae; Male; Molecular Structure; Phenanthrenes; Phenanthridines; Phytotherapy; Plant Extracts; Plant Roots; Prostatic Neoplasms

2013
Structure-activity relationship-guided development of retinoic acid receptor-related orphan receptor gamma (RORγ)-selective inverse agonists with a phenanthridin-6(5H)-one skeleton from a liver X receptor ligand.
    Bioorganic & medicinal chemistry, 2014, May-01, Volume: 22, Issue:9

    Topics: Drug Inverse Agonism; HEK293 Cells; Humans; Ligands; Liver X Receptors; Orphan Nuclear Receptors; Phenanthrenes; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Receptors, Retinoic Acid; Retinoic Acid Receptor gamma

2014
Palladium-catalyzed cyclization of benzamides with arynes: application to the synthesis of phenaglydon and N-methylcrinasiadine.
    Chemical communications (Cambridge, England), 2014, Oct-18, Volume: 50, Issue:81

    Topics: Acetonitriles; Benzamides; Benzene Derivatives; Catalysis; Cyclization; Heterocyclic Compounds, 4 or More Rings; Palladium; Phenanthrenes; Stereoisomerism

2014
Expression of human poly (ADP-ribose) polymerase 1 in Saccharomyces cerevisiae: Effect on survival, homologous recombination and identification of genes involved in intracellular localization.
    Mutation research, 2015, Volume: 774

    Topics: Blotting, Western; Cell Nucleus; Endopeptidases; Gene Expression Regulation; Genome, Fungal; Green Fluorescent Proteins; Histones; Homologous Recombination; Humans; Membrane Glycoproteins; Microscopy, Fluorescence; Mutation; Nuclear Pore; Phenanthrenes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Transcription Factors; Transgenes; Ultraviolet Rays

2015
Ligand Controlled Regiodivergent C1 Insertion on Arynes for Construction of Phenanthridinone and Acridone Alkaloids.
    Angewandte Chemie (International ed. in English), 2015, Dec-01, Volume: 54, Issue:49

    Topics: Acridones; Alkaloids; Alkynes; Catalysis; Ligands; Molecular Structure; Palladium; Phenanthrenes; Stereoisomerism

2015
Isolation and characterization of hepatitis C virus resistant to a novel phenanthridinone derivative.
    Antiviral chemistry & chemotherapy, 2015, Volume: 24, Issue:5-6

    Topics: Antiviral Agents; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Viral; Hepacivirus; Humans; Microbial Sensitivity Tests; Molecular Structure; Phenanthrenes; Structure-Activity Relationship; Virus Replication

2015
Microwave assisted synthesis of phenanthridinones and dihydrophenanthridines by vasicine/KOtBu promoted intramolecular C-H arylation.
    Organic & biomolecular chemistry, 2016, Sep-28, Volume: 14, Issue:36

    Topics: Alkaloids; Butanols; Microwaves; Molecular Structure; Phenanthrenes; Phenanthridines; Quinazolines

2016
Insights into the crystal structure of BRD2-BD2 - phenanthridinone complex and theoretical studies on phenanthridinone analogs.
    Journal of biomolecular structure & dynamics, 2018, Volume: 36, Issue:9

    Topics: Crystallography, X-Ray; Humans; Macromolecular Substances; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Phenanthrenes; Protein Binding; Protein Interaction Domains and Motifs; Protein Serine-Threonine Kinases; Structure-Activity Relationship; Transcription Factors

2018
Design, synthesis and biological evaluation of novel 1-phenyl phenanthridin-6(5H)-one derivatives as anti-tumor agents targeting TOPK.
    European journal of medicinal chemistry, 2019, Jan-15, Volume: 162

    Topics: Animals; Antineoplastic Agents; Apoptosis; Colorectal Neoplasms; Heterografts; Humans; Mice; Mitogen-Activated Protein Kinase Kinases; Phenanthrenes; Phenanthridines; Quinolones; Xenograft Model Antitumor Assays

2019
Discovery of novel phenanthridone derivatives with anti-streptococcal activity.
    Archives of microbiology, 2023, Nov-06, Volume: 205, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Mammals; Phenanthrenes; Phenanthridines; Streptococcus suis

2023